Hoshino Yuma 星野勇馬

… Alternative Names

HOSHINO Yuma 星野勇馬

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Researcher Number	00378746
Affiliation (Current)	2025: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2011 – 2013: 京都大学, 医学(系)研究科(研究院), 助教 2011 – 2012: 京都大学, 医学研究科, 特任講師 2010 – 2011: Kyoto University, 医学研究科, 助教 2010: 京都大学, 医学研究科呼吸器内科, 助教 2008 – 2009: Kyoto University, 医学研究科, 産学官連携研究員 2008 – 2009: 京都大学, 医学研究科, 産学連携研究員 2008: 京都大学, 産学官連携研究員
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / General physiology / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 慢性閉塞性肺疾患 / 獲得免疫 / 慢性肺疾患 / 喫煙 / Th17炎症 / 自己免疫 / COPD / 動物モデル / 閉塞性肺疾患 Except Principal Investigator 慢性閉塞性肺疾患 … More / 間欠的低酸素 / 持続的低酸素 / 低酸素 / II型肺胞上皮細胞 / 遺伝子多型 / 細胞・組織 / 再生医学 / sleepiness. / lipid metabolism, / hypertension, / hypoxemia, / BEAD-2B cell, / pluripotent stem cell, / sustained hypoxia, / intermittent hypoxia, / 呼気一酸化炭素 / 酸化ストレス / heme oxygenase-1 / 睡眠時無呼吸 / 閉塞型睡眠時無呼吸 / 低酸素誘導性因子 / 酸素代謝 / 低酸素誘導性因子1 / 麻酔科学 / 周術期 / HIF-1 / 分子生物学 / 細胞生物学 / 低酸素応答 / 麻酔薬 / 薬理学 / Birt-Hogg-Dube症候群 / 分化誘導 / I型肺胞上皮細胞 / 疾患特異的iPS / リンパ脈管筋腫症 / 若年性肺気腫 / 特発性間質性肺炎 / 肺胞上皮細胞 / 疾患特異iPS / 嚢胞性線維症 / Hermansky-Pudlak 症候群 / ３次元培養 / carboxypeptidase M / surfactant protein C / ES細胞 / iPS細胞 / MAPK / 歯周病 / 気道炎症 / 感染 / 宿主免疫 / 慢性感染 / COPD増悪 / 末梢気道 / 気道上皮細胞 / 気管支喘息 / COPD / 上皮間葉移行 / サーファクタントプロテインC / 肺障害 / 細胞培養 / 動物モデル / phenotyping / リモデリング / 骨そしょう症 / 胃食道逆流 / 体重減少 / 炎症 / 画像診断 Less

The development of methods to make changes in the property of induced pluripotent stem cells by the intermittent or sustained hypoxia.
- Principal Investigator
  
  CHIN Kazuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Kyoto University
Researches using iPS cells on intractable respiratory diseases to elucidate their pathogenesis and develop novel therapy.
- Principal Investigator
  
  MISHIMA MICHIAKI
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Investigation of molecular machamism of periopearetive oxygen metabolism regulation by hypoxia-inducible factors
- Principal Investigator
  
  HIROTA Kiichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyoto University
Gene polymorphisms in patients with sleep apnea and cell responses to hypoxia
- Principal Investigator
  
  TSUBOI Tomomasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Chronic infection and immune response in COPD patients
- Principal Investigator
  
  MURO Shigeo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Role of Th17 for persistent lung inflammation in COPDPrincipal Investigator
- Principal Investigator
  
  HOSHINO Yuma
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Mechanisms in epithelial-mesenchymal transition in chronic obstructive pulmonary disease
- Principal Investigator
  
  ITO Isao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Comprehensive study on the phenotyping of COPD
- Principal Investigator
  
  MISHIMA Michiaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University

All 2014 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 疾患の病因と病態COPD P38MAPK inhibitor.Annual Review呼吸器2010
- Author(s)
  室繁郎, 星野勇馬, 三嶋理晃
- Data Source
  KAKENHI-PROJECT-20590895
[Book] COPD Frontier, March Vol. 8 No. 1 20092009
- Author(s)
  星野勇馬, 室繁郎, 三嶋理晃
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-20590895
[Book] 【薬物療法の新展開】薬物療法の未来COPDの新規治療薬.COPD FRONTIER;8(1)
- Author(s)
  星野勇馬, 室繁郎, 三嶋理晃
- Data Source
  KAKENHI-PROJECT-20590895
[Book] 【COPD新ガイドラインで期待される予防と治療】慢性安定期の診療慢性安定期の治療.治療学;43(9)
- Author(s)
  室繁郎, 小川恵美子, 星野勇馬, 三嶋理晃
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice.2014
- Author(s)
  Marumo S, Hoshino Y, Kiyokawa H, Tanabe N, Sato A, Ogawa E, Muro S, Hirai T, Mishima M
- Journal Title
  
  BMC Pulm Med
  
  Volume: 14 Issue: 1
- DOI
  10.1186/1471-2466-14-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031
[Journal Article] Computed tomography assessment of pharmacological lung volume reduction induced by bronchodilators in COPD2012
- Author(s)
  Tanabe N, Muro S, Oguma T, Sato S, Kiyokawa H, Takahashi T, Kudo M, Kinose D, Kubo T, Hoshino Y, Ogawa E, Hirai T, Mishima M. COPD
- Journal Title
  
  COPD
  
  Volume: 9 Issue: 4 Pages: 1-8
- DOI
  10.3109/15412555.2012.674986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964, KAKENHI-PROJECT-22249031
[Journal Article] A NOD2 gene polymorphism is associated with the prevalence and severity of chronic obstructive pulmonary disease in a Japanese population2012
- Author(s)
  Kinose D, Ogawa E, Hirota T, Ito I, Kudo M, Haruna A, Marumo S, Hoshino Y, Muro S, Hirai T, Sakai H, Date H, Tamari M, Mishima M
- Journal Title
  
  Respirology
  
  Volume: 17(1) Issue: 1 Pages: 164-71
- DOI
  10.1111/j.1440-1843.2011.02069.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964, KAKENHI-PROJECT-23791204
[Journal Article] Emphysema distribution and annual changes in pulmonary function in male patients with chronic obstructive pulmonary disease2012
- Author(s)
  Tanabe N, Muro S, Tanaka S, Sato S, Oguma T, Kiyokawa H, Takahashi T, Kinose D, Hoshino Y, Kubo T, Ogawa E, Hirai T, Mishima M. Respir Res
- Journal Title
  
  Epub ahead of print
  
  Volume: 13(1) Issue: 1 Pages: 31-31
- DOI
  10.1186/1465-9921-13-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Impact of COPD Exacerbations on Osteoporosis Assessed by Chest CT Scan2012
- Author(s)
  Kiyokawa H, Muro S, Oguma T, Sato S, Tanabe N, Takahashi T, Kudo M, Kinose D, Kondoh H, Kubo T, Hoshino Y, Ogawa E, Hirai T, Mishima M
- Journal Title
  
  Epub
  
  Volume: 9(3) Issue: 3 Pages: 235-42
- DOI
  10.3109/15412555.2011.650243
- NAID
  120004873856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964, KAKENHI-PROJECT-21591559, KAKENHI-PROJECT-22590861
[Journal Article] Oxidative stress induced Interleukin-32 mRNA expression in human bronchial epithelial cells2012
- Author(s)
  Kudo M, Ogawa E, Kinose D, Haruna A, Takahashi T, Tanabe N, Marumo S, Hoshino Y, Hirai T, Sakai H, Muro S, Date H, Mishima M
- Journal Title
  
  Respir Res
  
  Volume: 13 Issue: 1 Pages: 19-19
- DOI
  10.1186/1465-9921-13-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Impact of exacerbations on emphysema progression in chronic obstructive pulmonary disease2011
- Author(s)
  Tanabe N, Muro S, Hirai T, Oguma T, Terada K, Marumo S, Kinose D, Ogawa E, Hoshino Y, Mishima M
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: 183(12) Issue: 12 Pages: 1653-9
- DOI
  10.1164/rccm.201009-1535oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Impact of Exacerbations on Emphysema Progression in Chronic Obstructive Pulmonary Disease.2011
- Author(s)
  Tanabe N, Muro S, Hirai T, Oguma T, Terada K, Marumo S, Kinose D, Ogawa E, Hoshino Y, Mishima M.
- Journal Title
  
  Am J Respir Crit Care Med
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Relationship between peripheralairway function and patient-reported outcomes in COPD : a cross-sectional study.2010
- Author(s)
  Haruna A, Oga T, Muro S, Ohara T, Sato S, Marumo S, Kinose D, Terada K, Nishioka M, Ogawa E, Hoshino Y, Hirai T, Chin K, Mishima M.
- Journal Title
  
  BMC Pulm Med 10
  
  Pages: 10-10
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Abnormal swallowing reflex and COPD exacerbations.2010
- Author(s)
  Terada K, Muro S, Ohara T, Kudo M, Ogawa E, Hoshino Y, Hirai T, Niimi A, Chin K, Mishima M.
- Journal Title
  
  Chest 137(2)
  
  Pages: 326-32
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Lipopolysaccharide induced connective tissue growth factor gene expression in human bronchial epithelial cells.2010
- Author(s)
  Nishioka M, Ogawa E, Kinose D, Haruna A, Ohara T, Ito I, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Hirai T, Muro S, Mishima M.
- Journal Title
  
  Respirology 15
  
  Pages: 669-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Relationship between peripheral airway function and patient-reported outcomes in COPD : a cross-sectional study2010
- Author(s)
  Haruna A, Oga T, Muro S, Ohara T, Sato S, Marumo S, Kinose D, Terada K, Nishioka M, Ogawa E, Hoshino Y, Hirai T, Chin K, Mishima M
- Journal Title
  
  BMC Pulm Med
  
  Volume: 10 Issue: 1 Pages: 10-10
- DOI
  10.1186/1471-2466-10-10
- NAID
  120004754366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Lipopolysaccharide induced connective tissue growth factor gene expression in human bronchial epithelial cells.2010
- Author(s)
  Nishioka M, Ogawa E, Kinose D, Haruna A, Ohara T, Ito I, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Hirai T, Muro S, Mishima M.
- Journal Title
  
  Respirology 15(4)
  
  Pages: 669-76
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Lipopolysaccharide induced connective tissue growth factor gene expression in human bronchial epithelial cells2010
- Author(s)
  Nishioka M, Ogawa E, Kinose D, Haruna A, Ohara T, Ito I, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Hirai T, Muro S, Mishima M
- Journal Title
  
  Respirology
  
  Volume: 15(4) Pages: 669-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] CT scan findings of emphysema predict mortality in COPD.2010
- Author(s)
  Haruna A, Muro S, Nakano Y, Ohara T, Hoshino Y, Ogawa E, Hirai T, Niimi A, Nishimura K, Chin K, Mishima M.
- Journal Title
  
  Chest 138(3)
  
  Pages: 635-40
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Abnormal swallowing reflex and COPD exacerbations2010
- Author(s)
  Terada K, Muro S, Ohara T, Kudo M, Ogawa E, Hoshino Y, Hirai T, Niimi A, Chin K, Mishima M
- Journal Title
  
  Chest
  
  Volume: 137(2) Issue: 2 Pages: 326-32
- DOI
  10.1378/chest.09-0482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] CT scan findings of emphysema predict mortality in COPD2010
- Author(s)
  Haruna A, Muro S, Nakano Y, Ohara T, Hoshino Y, Ogawa E, Hirai T, Niimi A, Nishimura K, Chin K, Mishima M
- Journal Title
  
  Chest
  
  Volume: 138(3) Issue: 3 Pages: 635-40
- DOI
  10.1378/chest.09-2836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Cough-reflex sensitivity to inhaled capsaicin in COPD associated with increased exacerbation frequency.2009
- Author(s)
  Ahsan MK, Okuyama H, Hoshino Y, Oka S, Masutani H, Yodoi J, Nakamura H.
- Journal Title
  
  Antioxid Redox Signal 11(10)
  
  Pages: 2573-2584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Thioredoxin 1 delivery as new therapeutics.2009
- Author(s)
  Nakamura H, Hoshino Y, Okuyama H, Matsuo Y, Yodoi J.
- Journal Title
  
  Adv Drug Deliv Rev 61(4)
  
  Pages: 303-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Cough-reflex sensitivity to inhaled capsaicin in COPD associated with increased exacerbation frequency.2009
- Author(s)
  Terada K, Muro S, Ohara T, Haruna A, Marumo S, Kudo M, Ogawa E, Hoshino Y, Hirai T, Niimi A, Mishima M.
- Journal Title
  
  Respirology 14(8)
  
  Pages: 1151-5
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Cough-reflex sensitivity to inhaled capsaicin in COPD associated with increased exacerbation frequency2009
- Author(s)
  Terada K, Muro S, Ohara T, Haruna A, Marumo S, Kudo M, Ogawa E, Hoshino Y, Hirai T, Niimi A, Mishima M
- Journal Title
  
  Respirology
  
  Volume: 14(8) Issue: 8 Pages: 1151-5
- DOI
  10.1111/j.1440-1843.2009.01620.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Protective effect of thioredoxin perfusion but not inhalation in warm ischemic-reperfused rat lungs.2009
- Author(s)
  Zhang J, Chen F, Nakamura T, Fujinaga T, Aoyama A, Hamakawa H, Sakai H, Hoshino Y, Yodoi J, Wada H, Bando T, Nakamura H.
- Journal Title
  
  Redox Rep 14(2)
  
  Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography.2008
- Author(s)
  Ohara T, Hirai T, Sato S, Terada K, Kinose D, Haruna A, Marumo S, Nishioka M, Ogawa E, Nakano Y, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Muro S, Mishima M.
- Journal Title
  
  Respirology 13(3)
  
  Pages: 372-8
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Impact of gastro-oesophageal reflux disease symptoms on COPD exacerbation.2008
- Author(s)
  Terada K, Muro S, Sato S, Ohara T, Haruna A, Marumo S, Kinose D, Ogawa E, Hoshino Y, Niimi A, Terada T, Mishima M.
- Journal Title
  
  Thorax 63(11)
  
  Pages: 951-5
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice2008
- Author(s)
  Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J.
- Journal Title
  
  J Pharmacol Exp Ther. 325(2)
  
  Pages: 380-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography2008
- Author(s)
  Ohara T, Hirai T, Sato S, Terada K, Kinose D, Haruna A, Marumo S, Nishioka M, Ogawa E,Nakano Y, Hoshino Y, Ito Y, Matsumoto H,Niimi A, Mio T, Chin K, Muro S, Mishima M.
- Journal Title
  
  Respirology 13(3)
  
  Pages: 372-8
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Redox-based therapeutics for lung diseases.2008
- Author(s)
  Hoshino Y, Mishima M.
- Journal Title
  
  Antioxid Redox Signal. 10(4)
  
  Pages: 701-4
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice2008
- Author(s)
  Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J
- Journal Title
  
  J Pharmacol Exp Ther 325(2)
  
  Pages: 380-8
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography.2008
- Author(s)
  Ohara T, Hirai T, Sato S, Terada K, Kinose D, Haruna A, Marumo S, Nishioka M, Ogawa E, Nakano Y, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Muro S, Mishima M.
- Journal Title
  
  Respirology. 13(3)
  
  Pages: 372-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Impact of gastro-oesophageal reflux disease symptoms on COPD exacerbation.2008
- Author(s)
  Terada K, Muro S, Sato S, Ohara T, Haruna A, Marumo S, Kinose D, Ogawa E, Hoshino Y, Niimi A, Terada T, Mishima M.
- Journal Title
  
  Thorax 63(11)
  
  Pages: 951-5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Redox-based therapeutics for lung diseases.2008
- Author(s)
  Hoshino Y, Mishima M.
- Journal Title
  
  Antioxid Redox Signal 10(4)
  
  Pages: 701-4
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Relationship between pulmonary emphysema and osteoporosis assessed by CT in patients with COPD.2008
- Author(s)
  Ohara T, Hirai T, Muro S, Haruna A, Terada K, Kinose D, Marumo S, Ogawa E, Hoshino Y, Niimi A, Chin K, Mishima M.
- Journal Title
  
  Chest 134(6)
  
  Pages: 1244-9
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Impact ofgastro-oesophageal reflux disease symptoms onCOPD exacerbation2008
- Author(s)
  Terada K, Muro S, Sato S, Ohara T, Haruna A,Marumo S, Kinose D, Ogawa E, Hoshino Y,Niimi A, Terada T, Mishima M
- Journal Title
  
  Thorax 63(11)
  
  Pages: 951-5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysemain mice2008
- Author(s)
  Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J.
- Journal Title
  
  J Pharmacol Exp Ther. 325(2)
  
  Pages: 380-8
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Relationship between pulmonary empliysema and osteoporosis assessed by CT in patients with COPD.2008
- Author(s)
  Ohara T, Hirai T, Muro S, Haruna A, Terada K, Kinose D, Marumo S, Ogawa E, Hoshino Y, Niimi A, Chin K, Mishima M.
- Journal Title
  
  Chest 134(6)
  
  Pages: 1244-9
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice.2008
- Author(s)
  Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J.
- Journal Title
  
  J Pharmacol Exp Ther 325(2)
  
  Pages: 380-8
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Redox-basedtherapeutics for lung diseases2008
- Author(s)
  Hoshino Y, Mishima M
- Journal Title
  
  Antioxid Redox Signal 10(4)
  
  Pages: 701-4
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Suppression of choroidal neovascularization by thioredoxin-1 via interaction with complement factor H.2008
- Author(s)
  Inomata Y, Tanihara H, Tanito M, Okuyama H, Hoshino Y, Kinumi T, Kawaji T, Kondo N, Yodoi J, Nakamura H.
- Journal Title
  
  Invest Ophthalmol Vis Sci 49(11)
  
  Pages: 5118-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590895
[Journal Article] Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography.2008
- Author(s)
  Ohara T, Hirai T, Sato S, Terada K, Kinose D, Haruna A, Marumo S, Nishioka M, Ogawa E, Nakano Y, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Muro S, Mishima M.
- Journal Title
  
  Respirology 13(3)
  
  Pages: 372-8
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Relationship between pulmonary emphysema and osteoporosis assessed by CT in patients with COPD2008
- Author(s)
  Ohara T, Hirai T, Muro S, Haruna A, Terada K,Kinose D, Marumo S, Ogawa E, Hoshino Y,Niimi A, Chin K, Mishima M.
- Journal Title
  
  Chest 134(6)
  
  Pages: 1244-9
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Neurotropin demonstrates cytoprotective effects in lung cells through the induction of thioredoxin-1.2007
- Author(s)
  Hoshino Y, Nakamura T, Sato A, Mishima M, Yodoi J, Nakamura H.
- Journal Title
  
  Am J Respir Cell Mol Biol. 37(4)
  
  Pages: 438-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Elevation of serum thioredoxin in patients with gefitinib-induced interstitial lung disease.2007
- Author(s)
  Sakuma K, Nakamura H, Nakamura T, Hoshino Y, Ueda S, Ichikawa M, Tabata C, Fujita S, Masago K, Yodoi J, Mishima M, Mio T.
- Journal Title
  
  Intern Med. 46(23)
  
  Pages: 1905-9
- NAID
  130000078603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Neurotropin demonstrates cytoprotective effects in lung cells through the induction of thioredoxin-12007
- Author(s)
  Hoshino Y, Nakamura T, Sato A, Mishima M,Yodoi J, Nakamura H
- Journal Title
  
  Am J Respir Cell MolBiol 37(4)
  
  Pages: 438-46
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-1 suppresses systemic inflammatory responses against cigarette smoking2006
- Author(s)
  Sato A, Hara T, Nakamura H, Kato N, Hoshino Y, Kondo N, Mishima M, Yodoi J.
- Journal Title
  
  Antioxid Redox Signal 8(9-10)
  
  Pages: 1891-6
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-l suppresses systemic inflammatory responses against cigarette smoking.2006
- Author(s)
  Sato A, Hara T, Nakamura H, Kato N, Hoshino Y, Kondo N, Mishima M
- Journal Title
  
  Antioxid Redox Signal 8 (9-10)
  
  Pages: 1891-1896
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Impact of gastro-oesophageal reflux disease symptoms on chronic obstructive pulmonary disease exacerbation.
- Author(s)
  Kunihiko Terada, Shigeo Muro, Susumu Sato, Tadashi Ohara, Akane Haruna, Satoshi Marumo, Daisuke Kinose, Emiko Ogawa, Yuma Hoshino, Akio Niimi, Michiaki Mishima.
- Journal Title
  
  Thorax (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Cough-ReflexSensitivity to Inhaled Capsaicin in ChronicObstructive Pulmonary Disease : the Impact onExacerbation Frequency
- Author(s)
  Kunihiko Terada, M.D., Shigeo Muro, M.D.,Ph. D., Tadashi Ohara, M.D., Ph. D., AkaneHaruna, M.D., Satoshi Marumo, M.D., MegumiKudo, M.D., Emiko Ogawa, M.D., Ph. D.,Yuma Hoshino, M.D., Ph. D., Toyohiro Hirai,M.D., Ph. D., Akio Niimi, M.D., Ph. D.,Michiaki Mishima, M.D., Ph. D.
- Journal Title
  
  Respirology (in press)
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Impact of COPD Exacerbations On Osteoporosis Assessed By Chest CT Scan2012
- Author(s)
  H. Kiyokawa, S. Muro, T. Oguma, S. Sato, N. Tanabe, T. Takahashi, M. Kudo, D. Kinose, Y. Hoshino, E. Ogawa, T. Hirai, M. Mishima
- Organizer
  American Thoracic Society Poster Discussion Session
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2012-05-22
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Correlation of Vascular Endothelial Growth Factor Receptor 2 With Pulmonary Function And Emphysematous Change In Early Chronic Obstructive Pulmonary Disease2012
- Author(s)
  T. Takahashi, E. Ogawa, A. Haruna, M. Kudo, H. Kiyokawa, N. Tanabe, D. Kinose, S. Sato, Y. Hoshino, T. Hirai, H. Sakai, Y. Nakano, S. Muro, M. Mishima
- Organizer
  American Thoracic Society Poster Session
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2012-05-22
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Animal Model Of Cigarette Smoke Induced Airway Disease Without Emphysema In Mice And Effect Of Dexamethasone On It.2011
- Author(s)
  Kiyokawa H, Hoshino Y, Tanabe N, Marumo S, Ogawa E, Muro S, Hirai T, Mishima M.
- Organizer
  2011 International Conference of American Thoracic Society.
- Place of Presentation
  Denver
- Year and Date
  2011-05-16
- Data Source
  KAKENHI-PROJECT-20590895
[Presentation] Oxidative stress augmented IL-32 gene upregulation in airway epithelial cells2010
- Author(s)
  M. Kudo, MD, E. Ogawa, MD, PhD, A. Haruna, MD, D. Kinose, MD., Y. Hoshino, MD, PhD, S. Muro, MD. PhD., T. Hirai, MD, PhD, M. Mishima, MD, PhD
- Organizer
  American Thoracic Society
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] The effect of telling smokers their "lung age" on smoking quit rate at annual health checkup2010
- Author(s)
  S. Marumo, MD1, S. Muro, MD. PhD. 1, A. Haruna, MD1, A. Sato, M. D., Ph. D. 2, E. Ogawa, MD, PhD1, Y. Hoshino, MD, PhD1, T. Hirai, MD, PhD1, M. Mishima, MD, PhD1, A. Sato, MD. PhD1
- Organizer
  American Thoracic Society Thematic Poster Session
- Year and Date
  2010-05-17
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] A single nucleotide polymorphism in NOD2 gene was associated with pathogenesis and severity of COPD2010
- Author(s)
  D. Kinose, E. Ogawa, T. Hirota, I. Ito, S. Muro, Y. Hoshino, T. Hirai, H. Sakai, M. Tamari, M. Mishima
- Organizer
  European Respiratory Society Barcelona
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] 全身性疾患としての睡眠時無呼吸症候群2010
- Author(s)
  谷澤公伸、陳和夫、星野勇馬、小賀徹
- Organizer
  第50回日本呼吸器学会学術講演会間欠的低酸素とSASシンポジウム12
- Place of Presentation
  京都国際会館(京都市)
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PROJECT-22590860
[Presentation] NOD2 SNPs associated with Crohn's disease were not found in Japanese COPD patients2010
- Author(s)
  E. Ogawa, MD, PhD, M. Nishioka, MD., Y. Hoshino, MD, PhD, T. Hirai, MD, PhD, S. Muro, MD. PhD
- Organizer
  American Thoracic Society Thematic Poster Session
- Year and Date
  2010-05-17
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Distinct responses against polyinosine-polycytidylic acid in smoke-exposed mouse strains with different susceptibility to emphysema2010
- Author(s)
  N. Tanabe, MD, Y. Hoshino, MD, PhD, H. Kiyokawa, MD, S. Marumo, MD, E. Ogawa, MD, PhD, S. Muro, MD, PhD, T. Hirai, MD, PhD, M. Mishima, MD, PhD
- Organizer
  American Thoracic Society
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] 全身性疾患としての睡眠時無呼吸症候群2010
- Author(s)
  谷澤公伸、陳和夫、星野勇馬、小賀徹
- Organizer
  第50回日本呼吸器学会学術集会シンポジウム 12 間欠的低酸素と SAS
- Place of Presentation
  京都市
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PROJECT-22590860
[Presentation] Effects of thioredoxin-1 on accelerated emphysema progression in cigarette smoke-exposed mice challenged with polyinosine-polycytidylic acid2010
- Author(s)
  N. Tanabe, Y. Hoshino, H. Kiyokawa, S. Marumo, E. Ogawa, S. Muro, T. Hirai, J. Yodoi, M. Mishima
- Organizer
  European Respiratory Society
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Distinct Responses Against Polyinosine-Polycytidylic Acid In Smoke-Exposed Mouse Strains With Different Susceptibility To Emphysema.2010
- Author(s)
  Tanabe N, Hoshino Y, Kiyokawa H, Marumo S, Ogawa E, Muro S, Hirai T, Mishima M.
- Organizer
  2010 International Conference of American Thoracic Society.
- Place of Presentation
  New Orleans.
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-20590895
[Presentation] Systemic immune activation by polyinosine-polycytidylic acid evokes lung inflammation similar to COPD exacerbation in smoke-exposed mice.2009
- Author(s)
  Tanabe N, Hoshino Y, Marumo S, Ito I, Ogawa E, Muro S, Hirai T, Mishima M.
- Organizer
  2009 International Conference of American Thoracic Society
- Place of Presentation
  San Diego.
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-20590895
[Presentation] Systemic Immune Activation by Polyinosine-Polycytidylic Acid Evokes Lung Inflammation Similar to COPD Exacerbation in Cigarette Smoke-Exposed Mice.2009
- Author(s)
  N.Tanabe, Y.Hoshino, S.Marumo, I.Ito, E.Ogawa, S.Muro, T.Hirai, M.Mishima.
- Organizer
  2009 International Conference of American Thoracic Society/American Lung Association
- Place of Presentation
  San Diego, USA
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-20590895
[Presentation] p38 MAPK is a major regulator of cigarette smoke-induced lung inflammation in mice2009
- Author(s)
  Marumo S, Hoshino Y, et al.
- Organizer
  American Thoracic Society
- Place of Presentation
  Toronto
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-20590895
[Presentation] Systemic Immune Activation by Polyinosine-Polycytidylic Acid Evokes Lung Inflammation Similar to COPD Exacerbation in Cigarette Smoke-Exposed Mice2009
- Author(s)
  N. Tanabe, MD, Y. Hoshino, MD, Ph, S. Marumo, MD, I. Ito, MD, Ph, E. Ogawa, MD, Ph, S. Muro, MD, Ph, T. Hirai, MD, Ph, M. Mishima, MD, Ph
- Organizer
  Thematic Poster Session
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] COPD Patients' Unmet Needs : The Japanese Experience.2009
- Author(s)
  Hoshino Y, Mishima M.
- Organizer
  First World Conference of COPD Patients. A Global Mandate for COPD Care.
- Place of Presentation
  Rome
- Year and Date
  2009-06-14
- Data Source
  KAKENHI-PROJECT-20590895
[Presentation] Pathophysiology of cigarette smoke induced emphysema after smoking cessation in a murine model.2009
- Author(s)
  Marumo S, Hoshino Y, Tanabe N, Sato A, Ito I, Ogawa E, Muro S, Hirai T, Mishima M.
- Organizer
  2009 International Conference of American Thoracic Society
- Place of Presentation
  San Diego.
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-20590895
[Presentation] Pathophysiology of Cigarette Smoke Induced Emphysema after Smoking Cessation in a Murine Model.2009
- Author(s)
  S.Marumo, Y.Hoshino, N.Tanabe, A.Sato, I.Ito, E.Ogawa, S.Muro, T.Hirai, M.Mishima.
- Organizer
  2009 International Conference of American Thoracic Society/American Lung Association
- Place of Presentation
  San Diego, USA
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-20590895
[Presentation] COPD Patients' Unmet Needs : The Japanese Experience.2009
- Author(s)
  Y.Hoshino, M.Mishima
- Organizer
  The First World Conference of COPD Patients
- Place of Presentation
  Rome, Italy
- Year and Date
  2009-06-14
- Data Source
  KAKENHI-PROJECT-20590895
[Presentation] Relation between smallairways and patient reported outcomes in chronic obstructive pulmonary disease2008
- Author(s)
  Akane Haruna, Toru Oga, Shigeo Muro, Tadashi Ohara, Kunihiko Terada, Daisuke Kinose, Satoshi Marumo, Yuma Hoshino, Toyohiro Hirai, Emiko Ogawa, Kazuo Chin, Michiaki Mishima
- Organizer
  2008 International Conference of American ThoracicSociety
- Place of Presentation
  Metro Toronto Convention Centre, Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Impaired swallowing reflex predisposes to COPD exacerbations2008
- Author(s)
  Kunihiko Terada, Shigeo Muro, TadashiOhara, Megumi Kudo, Emiko Ogawa, YumaHoshino, Toyohiro Hirai, Akio Niimi, MichiakiMishima
- Organizer
  18th Annual Conference of European Respiratory Society
- Place of Presentation
  Messe Sud, Berlin, Germany
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Arterial Hypoxia Correlated with the Inflammatory Profile in Induced Sputum from COPD Patients2007
- Author(s)
  Sato, S. Muro, S. Sato, M. Nishioka, Y. Hoshino, E. Ogawa, T. Hirai, H. Nakamura, J. Yodoi, M. Mishima
- Organizer
  2007 International Conference of American Thoracic Society
- Place of Presentation
  Moscone Convention Center, San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Impacts of gastro-oesophageal reflux symptoms on exacerbations of COPD2007
- Author(s)
  K. Terada, S. Muro, A. Niimi, E. Ogawa, Y. Hoshino, S. Sato, T. Ohara, D. Kinose, A. Haruna, S. Marumo, M. Mishima
- Organizer
  17th Annual Conference of European Respiratory Society
- Place of Presentation
  Stockholm International Fair and Congress Center, Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Thioredoxin Suppressed Cigarette Smoke Induced Emphysema in Mice2007
- Author(s)
  Sato, Y. Hoshino, M. Takenaka, S. Muro, H. Nakamura, J. Yodoi, M. Mishima
- Organizer
  2007 International Conference of American Thoracic Society
- Place of Presentation
  Moscone Convention Center, San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Corticosteroid Suppressed LPS Induced NOD2 Gene Expression in Airway Epithelial Cells/D2007
- Author(s)
  Kinose, E. Ogawa, M. Nishioka, Y. Hoshino, T. Hirai, S. Muro, M. Mishima
- Organizer
  2007 International Conference of American Thoracic Society
- Place of Presentation
  Moscone Convention Center, San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Thioredoxin Prevents Cigarette Smoke Induced Oxidative Stress and Apoptosis2006
- Author(s)
  A. Sato, Y. Hoshino, H. Nakamura, M.Narita, S. Muro, M. Mishima, J. Yodoi
- Organizer
  2006 International Conference of American Thoracic Society
- Place of Presentation
  San Diego Convention Center, San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-18209029

1. MURO Shigeo (60344454)

# of Collaborated Projects: 5 results

# of Collaborated Products: 61 results
2. MISHIMA Michiaki (60190625)

# of Collaborated Projects: 4 results

# of Collaborated Products: 47 results
3. ITO Isao (40447975)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
4. NIIMI Akio (30252513)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
5. OGAWA Emiko (00378671)

# of Collaborated Projects: 3 results

# of Collaborated Products: 35 results
6. CHIN Kazuo (90197640)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
7. HIRAI Toyohiro (20359805)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
8. OGA Toru (90378670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
9. NAKAMURA Hajime (70303914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. ITO Isao (40447959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NARUISHI Koji (00346446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SATO Susumu (40378691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
13. TAKASHIBA Shogo (50226768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SEYAMA Kuniaki (10226681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HANDA Tomohiro (10432395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MATSUMOTO Hisako (60359809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HEIKE Toshio (90190173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HIROTA Kiichi (00283606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KONDOH Shinae (40314182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TSUBOI Tomomasa (00536724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. HORIUCHI Hisanori (90291426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TOGUCHIDA Junya (40273502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 中野恭幸 (00362377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. 黄瀬大輔 (50572418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
25. 佐藤幸保 (00508236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 谷澤公伸 (20639140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hoshino Yuma 星野 勇馬

HOSHINO Yuma 星野 勇馬

Research Projects

Research Products

Co-Researchers

The development of methods to make changes in the property of induced pluripotent stem cells by the intermittent or sustained hypoxia.

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Researches using iPS cells on intractable respiratory diseases to elucidate their pathogenesis and develop novel therapy.

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Investigation of molecular machamism of periopearetive oxygen metabolism regulation by hypoxia-inducible factors

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Gene polymorphisms in patients with sleep apnea and cell responses to hypoxia

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Chronic infection and immune response in COPD patients

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Role of Th17 for persistent lung inflammation in COPDPrincipal Investigator

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Mechanisms in epithelial-mesenchymal transition in chronic obstructive pulmonary disease

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Comprehensive study on the phenotyping of COPD

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[Book] 疾患の病因と病態COPD P38MAPK inhibitor.Annual Review呼吸器2010

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[Book] COPD Frontier, March Vol. 8 No. 1 20092009

Author(s)

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Data Source

[Book] 【薬物療法の新展開】薬物療法の未来COPDの新規治療薬.COPD FRONTIER;8(1)

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Data Source

[Book] 【COPD新ガイドラインで期待される予防と治療】慢性安定期の診療慢性安定期の治療.治療学;43(9)

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[Journal Article] p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice.2014

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[Journal Article] Computed tomography assessment of pharmacological lung volume reduction induced by bronchodilators in COPD2012

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[Journal Article] A NOD2 gene polymorphism is associated with the prevalence and severity of chronic obstructive pulmonary disease in a Japanese population2012

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DOI

Hoshino Yuma 星野勇馬

HOSHINO Yuma 星野勇馬