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Takahashi Tetsuyuki  高橋 徹行

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TAKAHASHI TETSUYUKI  高橋 徹行

TAKAHASHI Tetsuyuki  高橋 徹行

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Researcher Number 00403692
Other IDs
Affiliation (Current) 2025: 武蔵野大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help 2025: 武蔵野大学, 薬学部, 講師
2021 – 2023: 武蔵野大学, 薬学部, 講師
2018: 武蔵野大学, 薬学部, 講師
2015 – 2017: 武蔵野大学, 付置研究所, 講師
2015 – 2017: 武蔵野大学, 薬学研究所, 講師 … More
2012 – 2013: 徳島大学, ヘルスバイオサイエンス研究部, 助教
2010 – 2011: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教
2007: The University of Tokushima, Institute of Health Biosciences, Graduate School, 助教
2006: 徳島大学, 大学院ヘルスバイオサイエンス研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Clinical oncology / Tumor therapeutics
Except Principal Investigator
Experimental pathology / Biological pharmacy
Keywords
Principal Investigator
がん細胞 / hnRNP A1 / boxB/lambdaNシステム / CCND1 mRNA / circRNA / lncRNA / miRNA / λN/boxBシステム / ノンコーディングRNA / 栄養飢餓状態 … More / hnRNP A1 / シグナルクロストーク / GGCT / グルタミン酸代謝 / メタボローム / がん / PGE2受容体 / 分子標的治療 / アラキドン酸代謝経路 / 癌 / エイコサノイド受容体 / エイコサノイド … More
Except Principal Investigator
prostate cancer / 骨転移 / 前立腺癌 / シード配列 / SV40 / マイクロRNA / VP1 / T抗原 / SV40ウイルス / miR-S1 / DNA複製 / 炎症性サイトカイン / SV40 / マイクロRNA / LSR / FABP4 / 肥満 / bone metastasis / bone marrow-derived stromal cells / 骨髄間質細胞 Less
  • Research Projects

    (8 results)
  • Research Products

    (40 results)
  • Co-Researchers

    (4 People)
  •  栄養飢餓状態下で特異的に惹起される新規小胞輸送制御機構の解明Principal Investigator

    • Principal Investigator
      高橋 徹行
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Musashino University
  •  Alteration of cancer cell traits by hnRNP A1 loss and subsequent ncRNA release during starvation.Principal Investigator

    • Principal Investigator
      Takahashi Tetsuyuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Musashino University
  •  A novel signaling crosstalk between prostaglandin E2 receptors and IGF-1 receptor as a possible molecular target for antitumor therapyPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Tetsuyuki
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Musashino University
  •  Role of fatty acid binding protein 4 (FABP4) as an exogenous ligand, on growth of prostate cancer cells

    • Principal Investigator
      UEHARA Hisanori
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokushima
  •  Functional roles of SV40 microRNA in host antiviral immunity.

    • Principal Investigator
      Hijikata Takao
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Musashino University
  •  Utility of arachidonic acid metabolism-related molecules as a novel target to anti-tumor strategyPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Tetsuyuki
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Clinical oncology
    • Research Institution
      The University of Tokushima
  •  Novel antitumor strategies by targeting to eicosanoid receptor-mediated cellular signalingPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Tetsuyuki
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Clinical oncology
    • Research Institution
      The University of Tokushima
  •  Trial of inhibition of prostate cancer cell growth in the bone using bone marrow-derived stem cells

    • Principal Investigator
      UEHARA Hisanori
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokushima

All 2024 2023 2022 2018 2017 2016 2015 2013 2012 2011 2007

All Journal Article Presentation

  • [Journal Article] Serum/glucose starvation strikingly reduce heterogeneous nuclear ribonucleoprotein A1 protein and its target, cyclin D12023

    • Author(s)
      Tetsuyuki Takahashi, Yuri Ando, Hirona Ichikawa, Koichi Tsuneyama, Takao Hijikata
    • Journal Title

      The FEBS Journal

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06538
  • [Journal Article] Serum/glucose starvation strikingly reduces heterogeneous nuclear ribonucleoprotein A1 protein and its target, cyclin D12023

    • Author(s)
      Takahashi Tetsuyuki、Ando Yuri、Ichikawa Hirona、Tsuneyama Koichi、Hijikata Takao
    • Journal Title

      The FEBS Journal

      Volume: 290 Issue: 16 Pages: 4126-4144

    • DOI

      10.1111/febs.16802

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07024, KAKENHI-PROJECT-21K06538
  • [Journal Article] SV40 miR-S1 and Cellular miR-1266 Sequester Each Other from Their Targets, Enhancing Telomerase Activity and Viral Replication2022

    • Author(s)
      Tetsuyuki Takahashi, Hirona Ichikawa, Yukiko Okayama, Manami Seki, Takao Hijikata
    • Journal Title

      Non-Coding RNA

      Volume: 8 Issue: 4 Pages: 57-57

    • DOI

      10.3390/ncrna8040057

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06538
  • [Journal Article] Tsumura-Suzuki obese diabetic mice-derived hepatic tumors closely resemble human hepatocellular carcinomas in metabolism-related genes expression and bile acid accumulation.2018

    • Author(s)
      Takahashi T, Deuschle U, Taira S, Nishida T, Fujimoto M, Hijikata T, Tsuneyama K
    • Journal Title

      Hepatol Int.

      Volume: in press Issue: 3 Pages: 254-261

    • DOI

      10.1007/s12072-018-9860-3

    • NAID

      120006632776

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Journal Article] Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice.2017

    • Author(s)
      Watanabe S, Takahashi T, Ogawa H, Uehara H, Tsunematsu T, Baba H, Morimoto Y, Tsuneyama K.
    • Journal Title

      Metab Syndr Relat Disord.

      Volume: 15(4) Issue: 4 Pages: 170-177

    • DOI

      10.1089/met.2016.0114

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K15740, KAKENHI-PROJECT-15K06873
  • [Journal Article] Histopathological characteristics of glutamine synthetase-positive hepatic tumor lesion in a mouse model of spontaneous metabolic syndrome (TSOD mouse).2016

    • Author(s)
      Tetsuyuki Takahashi, Takeshi Nishida, Hayato Baba, Hideki Hatta, Johji Imura, Mitsuko Sutoh, Syunji Toyohara, Ryoji Hokao, Syunsuke Watanabe, Hirohisa Ogawa, Hisanori Uehara, Koichi Tsuneyama.
    • Journal Title

      Mol. Clin. Oncol.

      Volume: 5 Pages: 267-270

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Journal Article] Inhibitory effect of soluble EP2 receptor on ovarian tumor growth in mice and utility of TMPRSS4 as a combinatorial molecular target.2013

    • Author(s)
      Tetsuyuki Takahashi, Hisanori Uehara, Keisuke Izumi
    • Journal Title

      International Journal of Oncology

      Volume: 43 Pages: 416-424

    • DOI

      10.3892/ijo.2013.1957

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24701026
  • [Journal Article] Inhibitory effect of soluble EP2 receptor on ovarian tumor growth in nude mice and utility of TMPRSS4 as a combinatorial molecular target2013

    • Author(s)
      Tetsuyuki Takahashi et al
    • Journal Title

      International Journal of Oncology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24701026
  • [Journal Article] The soluble EP2 receptor FuEP2/ Ex2 suppresses endometrial cancer cell growth in an orthotopic xenograft model in nude mice2011

    • Author(s)
      Tetsuyuki Takahashi, Hirohisa Ogawa, Keisuke Izumi, Hisanori Uehara
    • Journal Title

      Cancer Letters

      Volume: 306 Issue: 1 Pages: 67-75

    • DOI

      10.1016/j.canlet.2011.02.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700920
  • [Presentation] miR-4745-5pとmiR-6798-5pはhnRNP A1 mRNAを標的とする「飢餓特異的」miRNAである2024

    • Author(s)
      高橋徹行、船村麻衣、若井駿、市川裕菜、土方貴雄
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-21K06538
  • [Presentation] STAT1遺伝子のIFN依存性ポジティブ・フィードバック制御機構の解明2024

    • Author(s)
      湯浅勝敏、増渕愛美、新谷美穂、猪俣由以、庄司沙夜子、木田ほのか、岡田知、市川裕菜、高橋徹行、三原潔、土方貴雄
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-21K06538
  • [Presentation] 同種ウイルス粒子を用いたポリオーマウイルス関連疾患の新規治療戦略2024

    • Author(s)
      市川裕菜、石原大武、高橋徹行、土方貴雄
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-21K06538
  • [Presentation] 飢餓誘導性hnRNP A1タンパク消失機構に関与するmiRNAの解析2023

    • Author(s)
      高橋徹行、若井駿、船村麻衣、市川裕菜、土方貴雄
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-21K06538
  • [Presentation] ポリオーマウイルスのsmall t抗原によるIL-17F発現誘導機構の解明2023

    • Author(s)
      坂口陽花、市川裕菜、高橋徹行、土方貴雄
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-21K06538
  • [Presentation] 同種ウイルス粒子を用いたポリオーマウイルス関連疾患の新規治療戦略の検討2023

    • Author(s)
      市川裕菜、関愛美、高橋徹行、土方貴雄
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-21K06538
  • [Presentation] 飢餓状態下で起こるhnRNP A1タンパク消失に連動するCCND1レベルの低下2022

    • Author(s)
      安藤悠莉、高橋徹行、市川裕菜、土方貴雄
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-21K06538
  • [Presentation] 乳癌におけるがん免疫の応答性2018

    • Author(s)
      72)木田ほのか、青木寧々、高橋徹行、土方貴雄
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Presentation] ESR1発現欠損による乳がん悪性化の分子機序の解析2018

    • Author(s)
      青木寧々、青木夏美、木田ほのか、上原久典、高橋徹行、土方貴雄
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Presentation] 乳癌におけるがん免疫の応答性2018

    • Author(s)
      木田ほのか、青木寧々、高橋徹行、土方貴雄
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Presentation] ESR1発現欠損による乳がん悪性化の分子機序の解析2018

    • Author(s)
      71)青木寧々、青木夏美、木田ほのか、上原久典、高橋徹行、土方貴雄
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Presentation] 長期飼育によって発症するTSODマウス肝腫瘍の代謝プロファイル解析2017

    • Author(s)
      高橋徹行、常山幸一
    • Organizer
      第11回TSOD(肥満・糖尿病)マウス研究会情報交換会
    • Place of Presentation
      つくば研究支援センター
    • Year and Date
      2017-01-28
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Presentation] SV40ウイルスタンパク質による感染細胞の自然免疫応答の調節2017

    • Author(s)
      土方貴雄、高橋徹行
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-25460075
  • [Presentation] SV40-miR-S1の内因性テロメラーゼ発現に対する影響2017

    • Author(s)
      高橋徹行、岡山由紀子、土方貴雄
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2017-03-25
    • Data Source
      KAKENHI-PROJECT-25460075
  • [Presentation] Hyperinsulinemia, not hyperglycemia accelerates the progression of hepatocellular carcinoma in neonatal streptozotocin induced mouse model.2017

    • Author(s)
      Koichi Tsuneyama, Ryosuke Bessho, Masahiro Miki, Hayato Baba, Tetsuyuki Takahashi, Hirohisa Ogawa, Hisanori Uehara
    • Organizer
      The 68th Annual Meeting of American Association for the Study of Liver Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Presentation] SV40ウイルスタンパク質による感染細胞の自然免疫応答の調節2017

    • Author(s)
      土方貴雄、高橋徹行
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Presentation] SV40-miR-S1の内因性テロメラーゼ発現に対する影響2017

    • Author(s)
      高橋徹行、岡山由紀子、土方貴雄
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2017-03-25
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Presentation] プロスタグランジンE2受容体シグナリング阻害は膵臓がんにおけるIGF-1受容体シグナリングを介した増殖刺激を消失させる2016

    • Author(s)
      高橋徹行、上原久典、常山幸一、土方貴雄
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-15K06873
  • [Presentation] SV40-miR-S1の機能解析2016

    • Author(s)
      土方 貴雄、岡山 由紀子、高橋 徹行
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県 横浜市)
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-25460075
  • [Presentation] 脂肪細胞由来の FABP4 による前立腺癌細胞の骨内増殖促進2015

    • Author(s)
      上原 久典、高橋 徹行
    • Organizer
      第24回日本がん転移学会学術集会・総会
    • Place of Presentation
      シティプラザ大阪(大阪府大阪市中央区)
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-15K08403
  • [Presentation] Inhibitory effect of soluble EP2 receptor on ovarian tumor growth in nude mice and usefullness of TMPRSS4 as molecular target for synergistic efficacy.2013

    • Author(s)
      Tetsuyuki Takahashi, Hisanori Uehara, Keisuke Izumi
    • Organizer
      AACR 104st Annual Meeting
    • Place of Presentation
      Walter E. Washington Convention Center (Washington DC, USA)
    • Data Source
      KAKENHI-PROJECT-24701026
  • [Presentation] Inhibition of EP-mediated signaling influences growth stimulation by HB-EGF and IGF in pancreas cancer cells2013

    • Author(s)
      高橋徹行, 他
    • Organizer
      日本癌学会第72回総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-24701026
  • [Presentation] Inhibitory effect of soluble EP2 receptor on ovarian tumor growth in nude mice and usefullness of TMPRSS4 as molecular target for synergistic efficacy2013

    • Author(s)
      Tetsuyuki Takahashi et al.
    • Organizer
      AACR 104st Annual Meeting
    • Place of Presentation
      Walter E. Washington Convention Center(Washington DC, USA)
    • Data Source
      KAKENHI-PROJECT-24701026
  • [Presentation] 卵巣癌腹膜播種モデルにおける可溶性EP2受容体の腫瘍増殖抑制作用とそれに伴う発現変動遺伝子の解析2012

    • Author(s)
      高橋徹行, 他
    • Organizer
      第21回日本がん転移学会学術集会・総会
    • Place of Presentation
      オリエンタルホテル広島(広島県)
    • Data Source
      KAKENHI-PROJECT-24701026
  • [Presentation] Tumor suppressive effect of soluble EP2 receptor in the peritoneal dissemination model of ovarian cancer2012

    • Author(s)
      高橋徹行, 他
    • Organizer
      日本癌学会第71回総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-24701026
  • [Presentation] Tumor suppressive effect of soluble EP2 receptor in the peritoneal dissemination model of ovarian cancer2012

    • Author(s)
      高橋徹行 他
    • Organizer
      日本癌学会第71回総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-24701026
  • [Presentation] 卵巣癌腹膜播種モデルにおける可溶性EP2受容体の腫瘍増殖抑制作用とそれに伴う発現変動遺伝子の解析2012

    • Author(s)
      高橋徹行 他
    • Organizer
      第21回日本がん転移学会学術集会・総会
    • Place of Presentation
      オリエンタルホテル広島(広島県)
    • Data Source
      KAKENHI-PROJECT-24701026
  • [Presentation] 15-PGDH influences cell growth and susceptibility to apoptotic induction in pancreas cancer cells2011

    • Author(s)
      高橋徹行
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-22700920
  • [Presentation] 15-PGDH influences cell growth and susceptibility to apoptotic induction in pancreas cancer cells2011

    • Author(s)
      高橋徹行
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-22700920
  • [Presentation] 「研究成果報告書概要(和文)」より2007

    • Author(s)
      高橋 徹行
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-18590373
  • [Presentation] Utilization of EP2 receptor fragment which inhibits PGE2 binding to its receptor2007

    • Author(s)
      TAKAHASHI, Tetsuyuki
    • Organizer
      66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590373
  • 1.  UEHARA Hisanori (30263809)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 2.  Hijikata Takao (70189786)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  常山 幸一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 4.  井之上 浩一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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