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Tsuneyama Koichi  常山 幸一

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TSUNEYAMA Koichi  常山 幸一

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Researcher Number 10293341
Other IDs
External Links
Affiliation (Current) 2022: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
Affiliation (based on the past Project Information) *help 2017 – 2022: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
2015 – 2016: 徳島大学, 大学院医歯薬学研究部(医学系), 教授
2015: 徳島大学, 大学院医歯薬学研究部, 教授
2014: 徳島大学, ヘルスバイオサイエンス研究部, 教授
2012 – 2013: 富山大学, 大学院医学薬学研究部(医学), 准教授 … More
2008 – 2013: 富山大学, 医学薬学研究部(医学), 准教授
2009 – 2012: University of Toyama, 大学院・医学薬学研究部(医学), 准教授
2007: University of Toyama, Graduate School of Medical and Pharmaceutical Science, Associate Professor
2006: Toyama University, Diagnostic Pathology, associate professor, 大学院医学薬学研究部, 准教授
2006: 富山大学, 大学院医学薬学研究部, 助教授
2005: 富山大学, 医学部, 助教授
2004: Toyama Medical and Pharmaceutical Univ., Dept.of Medicine, A.Professor, 医学部・第一病理学講座, 助教授
2003 – 2004: 富山医科薬科大学, 医学部, 助教授
2001 – 2002: 金沢大学, 大学院・医学系研究科, 助手
2001: 金沢大学, 大学院・医学研究科, 助手
1998 – 2000: 金沢大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Human pathology / Human pathology / Experimental pathology / Basic Section 49030:Experimental pathology-related / General internal medicine (including Psychosomatic medicine)
Except Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related / General internal medicine (including Psychosomatic medicine) / Human pathology / Design and evaluation of sustainable and environmental conscious system / Human pathology … More / Metabolomics / Applied health science / Basic Section 53020:Cardiology-related / Basic Section 56020:Orthopedics-related / Basic Section 49030:Experimental pathology-related Less
Keywords
Principal Investigator
NASH / 動物モデル / 肝内結石症 / 肝線維化 / c-kit / 原発性胆汁性肝硬変 / 酸化ストレス / 漢方薬 / 質量分析 / 短鎖脂肪酸 … More / 肥満細胞 / Stem Cell Factor (SCF) / 原発性硬化性胆管炎 / b-FGF / TNF-α / stem cell factor(SCF) / 原発性硬化性肝管炎 / stem cell factor / 多分化能 / 肝臓 / 幹細胞 / 胆管 / 胆道アレルギー / ケモカイン / サイトカイン / 胆管上皮細胞 / 細菌菌体成分 / ケイモカイン / 糖尿病 / ミトコンドリア / 高コレステロール食 / Galectin-3 / 脂質過酸化 / 80OHdG / 80HdG / 疾患モデル動物 / NASH, PBC,酸化ストレス / PBC / メタボリックシンドローム / 質量顕微鏡 / 重金属 / カドミウム / X線マイクロアナライザー / イタイイタイ病 / 病理標本 / 糖化反応 / AGE / RAGE / ガレクチン3 / animal model / oxidative stress / glycation / herval medicine / 自己免疫疾患 / 化学物質 / イメージング / ナノ粒子 / 原発性胆汁性胆管炎 / 非アルコール性脂肪肝炎 / 胆汁酸 / ラマン顕微鏡 / 肝細胞癌 / 非アルコール性脂肪性肝炎 / イメージング質量分析 / BDNF / 非アルコール性脂肪性肝疾患 / うつ病 … More
Except Principal Investigator
漢方薬 / 動物モデル / α-tubulin / EBV / p53 / 肥満 / 糖尿病 / マクロファージ / 肝細胞癌 / 腫瘍微小環境 / 肝星細胞 / 認知症モデル / メディエータ / 脳虚血 / 加齢 / dementia model / Kampo medicine / vascular endothelial growth factor / neuroplasticity / aging / platelet derived growth factor / ischemia / mediator(s) / anti-dementia drug / emotional disoders / Senescence-accelerated mouse / 胆汁酸 / トリグリセリド / 一価不飽和脂肪酸 / ステアリン酸CoA不飽和化酵素1 / ステアリン酸CoA不飽和化酵素1 / コレステロールエステル / トランスアミナーゼ / コール酸 / 肝傷害 / エイコサペンタエン酸 / リポプロテインリパーゼ / 隔離飼育 / 注意欠陥多動性障害モデル / 注意様行動 / 社会性 / 恐怖条件付け記憶 / 発症因子 / 初期増殖応答蛋白1 / 隔離飼育ストレス / ADHD動物モデル / 不注意様行動 / 恐怖記憶 / 神経シグナリング系 / 初期増殖応答蛋白1 / 長期記憶 / 初期増殖応答蛋白質1 / 初期増殖応答タンパク質1 / 潜在学習 / 注意力 / 攻撃性 / 海藻分解菌 / 廃棄海藻 / バイオマス利活用 / 人体病理学 / 肝臓病理 / 分子生物学 / 先天性肝線維症 / カロリ病 / PCKラット / サイトケラチン20 / 上皮成長因子 / 細胞内シグナル伝達 / 細胞増殖 / 肝内胆管 / 体染色体性劣性遺伝 / アポトーシス / cDNAマイクロアレイ / TGF-βファミリー / Human Pathology / Pathology of Liver / Molecular Biology / Congenital Hepatic Fibrosis / Caroli's Disease / Animal Model / PCK Rat / 悪性腫瘍 / 予後因子 / 予後 / Malignant tumor / Prognosis / 胃癌 / 遺伝子多型 / gastric cancer / polymorphism / 肝がん / HIF-1a / 低酸素 / HIF-1 / 肝細胞がん / 腫瘍関連マクロファージ / 肝移植 / 再発 / グラフト内再発 / 非アルコール性肝障害 / 細胞モデル / ヒト試験 / 酸化ストレスマーカー / 一重項酸素 / 早期診断 / バイオマーカー / 機能性因子 / 発症メカニズム解析 / 酸化ストレス / 動物試験 / 細胞試験 / 生活習慣病 / 合併症 / 眼疾患 / 脂肪肝炎 / 肝再生 / 肝微小環境 / 脂肪組織 / 腸肝関連 / 肝不全 / NASH / NAFLD / 腸管関連 / 電気的ストーム / 心筋代謝リモデリング / 神経型Naチャネル / トルサードドポアント / 遅延ナトリウム電流 / 神経型ナトリウムチャネル / メタボリックシンドローム / ロコモティブシンドローム / サルコペニア / 2型糖尿病 / オルガノイド / 脂肪由来幹細胞 / 超高機能肝細胞様細胞 / 肝細胞様細胞 / HLC / 非アルコール性脂肪性肝炎 / 腸内細菌叢 / 線維化 / 薬剤耐性肝癌 / 癌関連線維芽細胞 / 薬剤耐性 / 転移抑制 Less
  • Research Projects

    (27 results)
  • Research Products

    (332 results)
  • Co-Researchers

    (130 People)
  •  オルガノイドを用いた脂肪由来幹細胞からの超高機能肝細胞様細胞の確立

    • Principal Investigator
      島田 光生
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      The University of Tokushima
  •  肝臓マクロファージサブセット解析から迫る新規線維化亢進NASHマウスの病態解明

    • Principal Investigator
      長井 良憲
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Toyama Prefectural University
  •  Elucidation of the pathogenesis and new therapeutic strategies for brain- and gut-related steatohepatitis based on brain-derived neurotrophic factorPrincipal Investigator

    • Principal Investigator
      常山 幸一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      The University of Tokushima
  •  肝星細胞制御による薬剤耐性肝癌の肝内転移抑制機構の解明

    • Principal Investigator
      居村 暁
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      The University of Tokushima
  •  神経型ナトリウムチャネルを標的とする新しい抗不整脈薬開発のための基盤研究

    • Principal Investigator
      辻 幸臣
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Nagasaki University
  •  メタボリックシンドロームが運動器機能に及ぼす影響と運動療法による改善機序の解明

    • Principal Investigator
      西良 浩一
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      The University of Tokushima
  •  Elucidation of the role of bile acids and short-chain fatty acids in the onset and progression of non-alcoholic steatohepatitisPrincipal Investigator

    • Principal Investigator
      TSUNEYAMA Koichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      The University of Tokushima
  •  Mechanism of suppressive effect for intrahepatic recurrence of hepatocellular carcinoma by hepatic stellate cell regulation after liver transplantation

    • Principal Investigator
      IMURA Satoru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      The University of Tokushima
  •  Development of integrated treatment for impaired liver regeneration on non-alcoholic steatohepatitis

    • Principal Investigator
      SHIMADA Mitsuo
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      The University of Tokushima
  •  非アルコール性肝障害の発症機序解明および早期診断法の確立と予防法の提案

    • Principal Investigator
      吉田 康一
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied health science
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Establishment of new analytical method for visualizing chemical agents and xenobiotics on pathology specimentsPrincipal Investigator

    • Principal Investigator
      TSUNEYAMA Koichi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokushima
  •  Development of methods for reducing volume and reutilization of waste seaweeds with a novel species bacterium Myt-1 capable of degrading seaweeds.

    • Principal Investigator
      Nakamura Shogo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Design and evaluation of sustainable and environmental conscious system
    • Research Institution
      University of Toyama
  •  Pathological analysis of cadmium and its microenvironment in patients with itai-itai diseasePrincipal Investigator

    • Principal Investigator
      TSUNEYAMA Koichi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokushima
      University of Toyama
  •  Effect of obesity and diabetes on liver cancer and tumor-associated macrophage polarization

    • Principal Investigator
      USUI Isao
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      University of Toyama
  •  New analytical technology in the field of pathology clarified effectiveness of Kampo formulaPrincipal Investigator

    • Principal Investigator
      TSUNEYAMA Koichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      The University of Tokushima
      University of Toyama
  •  Kampo medicine pharmacology-based clarification and identification of etiologic factors and their function responsible for ADHD

    • Principal Investigator
      MATSUMOTO KINZO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama
  •  Detection of novel actions of kampo medicines for lipid metabolism by lipidomic analysis

    • Principal Investigator
      SHIRO Watanabe
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama
  •  Sharing pathogenic mechanism between non-alcoholic steatohepatitis and primary biliary cirrhosisPrincipal Investigator

    • Principal Investigator
      TSUNEYAMA Koichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Toyama
  •  Studies on endogenous neuronal mediator with responsibility for anti-dementia effect of Kampo medicine

    • Principal Investigator
      MATSUMOTO Kinzo
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama
  •  Molecular pathological analysis of pathogenesis of non-alcoholic steatohepatitis: Propose of new treatment approachPrincipal Investigator

    • Principal Investigator
      TSUNEYAMA Koichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      University of Toyama
  •  Role of p 53 codon 72 polymorphism in EBV-related gastric cancer

    • Principal Investigator
      MURAI Yoshihiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Toyama University
  •  非アルコール性脂肪性肝炎発症・進展に関する脂質過酸化、及び糖化反応の役割Principal Investigator

    • Principal Investigator
      常山 幸一
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Toyama
      Toyama Medical and Pharmaceutical University
  •  Study on the role of mutated α-tubulin in the progression of malignant tumors

    • Principal Investigator
      TAKANO Yasuo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
  •  胆道系におけるアレルギー機序の解明Principal Investigator

    • Principal Investigator
      常山 幸一
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      Toyama Medical and Pharmaceutical University
      Kanazawa University
  •  ヒト肝臓の幹細胞の研究:c-kit 受容体-stem cell factor系の発現を中心にPrincipal Investigator

    • Principal Investigator
      常山 幸一
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human pathology
    • Research Institution
      Kanazawa University
  •  Pathological and biological analysis of congenital hepatic fibrosis and Caroli's disease -A comparative study using an animal model for the disease

    • Principal Investigator
      NAKANUMA Yasuni
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Kanazawa University
  •  慢性胆管炎・特に肝内結石症での胆管硬化と肥満細胞との関連性・胆管上皮でのStem Cell Factorの発現を中心にしてPrincipal Investigator

    • Principal Investigator
      常山 幸一
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human pathology
    • Research Institution
      Kanazawa University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Rotors anchored by refractory islands drive torsades de pointes in an experimental model of electrical storm2022

    • Author(s)
      Yamazaki M, Makita N, Tsuji Y, et al.
    • Journal Title

      Heart Rhythm

      Volume: 19 Pages: 318-329

    • DOI

      10.1016/j.hrthm.2021.10.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0245, KAKENHI-PROJECT-19H04443, KAKENHI-PROJECT-21H02920, KAKENHI-PROJECT-20K08450, KAKENHI-PROJECT-21K19913, KAKENHI-PROJECT-21K18036
  • [Journal Article] The survival and proliferation of osteosarcoma cells are dependent on the mitochondrial BIG3-PHB2 complex formation2021

    • Author(s)
      Toki Shunichi、Yoshimaru Tetsuro、Matsushita Yosuke、Aihara Hitoshi、Ono Masaya、Tsuneyama Koichi、Sairyo Koichi、Katagiri Toyomasa
    • Journal Title

      Cancer Sci.

      Volume: 112 Pages: 4208-4219

    • DOI

      10.1111/cas.15099

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07643, KAKENHI-PROJECT-20H00543, KAKENHI-PROJECT-20K08958, KAKENHI-PROJECT-20K09435
  • [Journal Article] Development of a novel mouse model of diet-induced nonalcoholic steatohepatitis?related progressive bridging fibrosis2021

    • Author(s)
      Ichimura-Shimizu Mayuko、Omagari Katsuhisa、Yamashita Michiko、Tsuneyama Koichi
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: 85 Pages: 941-947

    • DOI

      10.1093/bbb/zbaa107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K19676, KAKENHI-PROJECT-18K07069
  • [Journal Article] Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanism2020

    • Author(s)
      Matsumoto Minoru、Tsuneyama Koichi、Morimoto Junko、Hosomichi Kazuyoshi、Matsumoto Mitsuru、Nishijima Hitoshi
    • Journal Title

      International Immunology

      Volume: 32 Pages: 117-131

    • DOI

      10.1093/intimm/dxz066

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19K07626, KAKENHI-PROJECT-19K16613, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06502, KAKENHI-PUBLICLY-19H05344, KAKENHI-PROJECT-19H03699, KAKENHI-PROJECT-17K08885, KAKENHI-PROJECT-18K19564, KAKENHI-PLANNED-16H06496
  • [Journal Article] Comprehensive analysis of liver and blood miRNA in precancerous conditions.2020

    • Author(s)
      Umezu Tomohiro、Tsuneyama Koichi、Kanekura Kohsuke、Hayakawa Michiyo、Tanahashi Toshihito、Kawano Mitsuoki、Taguchi Y-h、Toyoda Hidenori、Tamori Akihiro、Kuroda Masahiko、Murakami Yoshiki
    • Journal Title

      Sci Rep.

      Volume: 10 Pages: 1-11

    • DOI

      10.1038/s41598-020-78500-1

    • NAID

      120007193757

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K12067, KAKENHI-PROJECT-20H03593, KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-18K07244, KAKENHI-PUBLICLY-19H05270, KAKENHI-PUBLICLY-20H04848
  • [Journal Article] Smad Phospho-Isoforms for Hepatocellular Carcinoma Risk Assessment in Patients with Nonalcoholic Steatohepatitis2020

    • Author(s)
      Suwa Kanehiko、Yamaguchi Takashi、Yoshida Katsunori、Murata Miki、Ichimura Mayuko、Tsuneyama Koichi、Seki Toshihito、Okazaki Kazuichi
    • Journal Title

      Cancers

      Volume: 12 Pages: 286-286

    • DOI

      10.3390/cancers12020286

    • NAID

      120006894613

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17415, KAKENHI-PROJECT-18K07069
  • [Journal Article] Pharmacological Characterization of a Novel Mouse Model of Cholestatic Pruritus2020

    • Author(s)
      Andoh Tsugunobu、Suzuki Kazunari、Konno Mitsuhiro、Tsuneyama Koichi、Kuraishi Yasushi
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 43 Issue: 7 Pages: 1111-1117

    • DOI

      10.1248/bpb.b20-00097

    • NAID

      130007867928

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Exacerbation of gefitinib-induced liver injury by glutathione reduction in mice2020

    • Author(s)
      Oda Shingo、Miyazaki Nanaka、Tsuneyama Koichi、Yokoi Tsuyoshi
    • Journal Title

      J. Toxicol. Sci.

      Volume: 45 Issue: 8 Pages: 493-502

    • DOI

      10.2131/jts.45.493

    • NAID

      130007884274

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19K07099
  • [Journal Article] Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis2020

    • Author(s)
      Takai Atsuko、Kikuchi Kentaro、Ichimura Mayuko、Tsuneyama Koichi、Moritoki Yuki、Matsumoto Kotaro、Tsunashima Hiromichi、Onda Takeshi、Kuniyoshi Noriyuki、Nariyama Tomoyuki、Ohyatsu Sho、Kubota Juri、Nagumo Kozue、Sato Shinpei、Hara Masumi、Miyakawa Hiroshi
    • Journal Title

      BMC Gastroenterology

      Volume: 20

    • DOI

      10.1186/s12876-020-01194-2

    • NAID

      120006842035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Molecular imaging analysis of microvesicular and macrovesicular lipid droplets in non-alcoholic fatty liver disease by Raman microscopy2020

    • Author(s)
      Minamikawa T, Ichimura-Shimizu M, Takanari H, Morimoto Y, Shiomi R, Tanioka H, Hase E, Yasui T, Tsuneyama K.
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 18548-18548

    • DOI

      10.1038/s41598-020-75604-6

    • NAID

      120006959724

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H04443, KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19K22969
  • [Journal Article] Modulation of sphingosine 1‐phosphate by hepatobiliary cholesterol handling2020

    • Author(s)
      Kurano Makoto、Tsukamoto Kazuhisa、Hara Masumi、Tsuneyama Koichi、Nishikawa Takako、Ikeda Hitoshi、Yatomi Yutaka
    • Journal Title

      The FASEB Journal

      Volume: 34 Pages: 14655-14670

    • DOI

      10.1096/fj.202001397r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03573, KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19K16972
  • [Journal Article] Analysis of amino acid profiles of blood over time and biomarkers associated with non-alcoholic steatohepatitis in STAM mice2019

    • Author(s)
      Iida Ayaka、Kuranuki Sachi、Yamamoto Ryoko、Uchida Masaya、Ohta Masanori、Ichimura Mayuko、Tsuneyama Koichi、Masaki Takayuki、Seike Masataka、Nakamura Tsuyoshi
    • Journal Title

      Experimental Animals

      Volume: 68 Issue: 4 Pages: 417-428

    • DOI

      10.1538/expanim.18-0152

    • NAID

      130007742195

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19K02352, KAKENHI-PROJECT-17H00881, KAKENHI-PROJECT-17K00930
  • [Journal Article] Development of a novel aortic dissection mouse model and evaluation of drug efficacy using in-vivo assays and database analyses.2019

    • Author(s)
      Izawa-Ishizawa Yuki、Imanishi Masaki、Zamami Yoshito、Toya Hiroki、Nagao Tomoko、Morishita Marin、Tsuneyama Koichi、Horinouchi Yuya、Kihira Yoshitaka、Takechi Kenshi、Ikeda Yasumasa、Tsuchiya Koichiro、Yoshizumi Masanori、Tamaki Toshiaki、Ishizawa Keisuke
    • Journal Title

      J Hypertens.

      Volume: 37 Pages: 1-1

    • DOI

      10.1097/hjh.0000000000001898

    • NAID

      120006627861

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06686, KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983, KAKENHI-PROJECT-16K08272, KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-18K14920
  • [Journal Article] Age-Related Alterations of Nonalcoholic Steatohepatitis in Sprague-Dawley Rats Fed a High-Fat and High-Cholesterol Diet2019

    • Author(s)
      OMAGARI Katsuhisa、ASAKAWA Eri、SASAO Marin、NARITA Sumire、HISANO Mei、FUKUDA Ayumi、SURUGA Kazuhito、ICHIMURA Mayuko、TSUNEYAMA Koichi
    • Journal Title

      J Nutr Sci Vitaminol

      Volume: 65 Issue: 4 Pages: 349-356

    • DOI

      10.3177/jnsv.65.349

    • NAID

      130007697552

    • ISSN
      0301-4800, 1881-7742
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19K11721
  • [Journal Article] Two cases of non-mucinous cystadenomas of the pancreas with pancreatobiliary phenotype and ovarian-like stroma2019

    • Author(s)
      Yamashita Shoko、Ikemoto Tetsuya、Morine Yuji、Imura Satoru、Iwahashi Shuichi、Saito Yu、Yamada Shinichiro、Yoshimoto Toshiaki、Tsuneyama Koichi、Shimada Mitsuo
    • Journal Title

      Surgical Case Reports

      Volume: 5 Pages: 117-117

    • DOI

      10.1186/s40792-019-0673-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Dietary fat, cholesterol, and cholic acid affect the histopathologic severity of nonalcoholic steatohepatitis in Sprague-Dawley rats2019

    • Author(s)
      Fukuda Ayumi、Sasao Marin、Asakawa Eri、Narita Sumire、Hisano Mei、Suruga Kazuhito、Ichimura Mayuko、Tsuneyama Koichi、Tanaka Kazunari、Omagari Katsuhisa
    • Journal Title

      Pathology - Research and Practice

      Volume: 215 Pages: 152599-152599

    • DOI

      10.1016/j.prp.2019.152599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Macrophage-specific hypoxia-inducible factor-1α deletion suppresses the development of liver tumors in high-fat diet-fed obese and diabetic mice2019

    • Author(s)
      Takikawa Akiko、Usui Isao、Fujisaka Shiho、Tsuneyama Koichi、Okabe Keisuke、Nakagawa Takashi、Nawaz Allah、Kado Tomonobu、Jojima Teruo、Aso Yoshimasa、Hayakawa Yoshihiro、Yagi Kunikimi、Tobe Kazuyuki
    • Journal Title

      J Diabetes Investig.

      Volume: in press Pages: 1411-1418

    • DOI

      10.1111/jdi.13047

    • NAID

      120006980551

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-18K16193, KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-17K16143, KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204, KAKENHI-PLANNED-17H06398
  • [Journal Article] Hepatic Campylobacter jejuni infection in patients with Castleman‐Kojima disease (idiopathic multicentric Castleman disease with thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome)2019

    • Author(s)
      Kageyama Chihiro、Igawa Takuro、Gion Yuka、Iwaki Noriko、Tabata Tetsuya、Tanaka Takehiro、Kondo Eisei、Sakai Hajime、Tsuneyama Koichi、Nomoto Kazuhiro、Noguchi Hiroko、Yoshino Tadashi、Yokota Kenji、Sato Yasuharu
    • Journal Title

      Pathology International

      Volume: 69 Pages: 572-579

    • DOI

      10.1111/pin.12856

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Experimental Evidence of Liver Injury by BSEP-Inhibiting Drugs With a Bile Salt Supplementation in Rats2019

    • Author(s)
      Yang Fuhua、Takeuchi Taiki、Tsuneyama Koichi、Yokoi Tsuyoshi、Oda Shingo
    • Journal Title

      Toxicological Sciences

      Volume: in press

    • DOI

      10.1093/toxsci/kfz088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Apolipoprotein M suppresses the phenotypes of IgA nephropathy in hyper-IgA mice2019

    • Author(s)
      Kurano Makoto、Tsuneyama Koichi、Morimoto Yuki、Nishikawa Masako、Yatomi Yutaka
    • Journal Title

      The FASEB Journal

      Volume: 33 Pages: 5181-5195

    • DOI

      10.1096/fj.201801748r

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-16H06236
  • [Journal Article] Inhibition of EP2/EP4 prostanoid receptor-mediated signaling suppresses IGF-1-induced proliferation of pancreatic cancer BxPC-3?cells via upregulating γ-glutamyl cyclotransferase expression2019

    • Author(s)
      Takahashi Tetsuyuki、Ichikawa Hirona、Morimoto Yuuki、Tsuneyama Koichi、Hijikata Takao
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 516 Pages: 388-396

    • DOI

      10.1016/j.bbrc.2019.06.054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Establishment of a novel mouse model of troglitazone-induced liver injury and analysis of its hepatotoxic mechanism.2019

    • Author(s)
      Jia Ru、Oda Shingo、Tsuneyama Koichi、Urano Yuya、Yokoi Tsuyoshi
    • Journal Title

      Journal of Applied Toxicology

      Volume: 39 Pages: 1541-1556

    • DOI

      10.1002/jat.3838

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19H03388
  • [Journal Article] A fermented mixed tea made with camellia (Camellia japonica) and third-crop green tea leaves prevents nonalcoholic steatohepatitis in Sprague-Dawley rats fed a high-fat and high-cholesterol diet2018

    • Author(s)
      Katsuhisa Omagari, Kazuhito Suruga, Akira Kyogoku, Satomi Nakamura, Ai Sakamoto, Shinta Nishioka, Mayuko Ichimura, Yuji Miyata, Koichi Tajima, Koichi Tsuneyama, Kazunari Tanaka
    • Journal Title

      HepatoBiliary Surgery and Nutrition

      Volume: - Pages: 175-184

    • DOI

      10.21037/hbsn.2017.08.03

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K00835, KAKENHI-PROJECT-18K07069
  • [Journal Article] Gut microbiota translocation promotes autoimmune cholangitis2018

    • Author(s)
      Ma Hong-Di、Zhao Zhi-Bin、Ma Wen-Tao、Liu Qing-Zhi、Gao Cai-Yue、Li Liang、Wang Jinjun、Tsuneyama Koichi、Liu Bin、Zhang Weici、Zhou Yongjian、Gershwin M. Eric、Lian Zhe-Xiong
    • Journal Title

      Journal of Autoimmunity

      Volume: 95 Pages: 47-57

    • DOI

      10.1016/j.jaut.2018.09.010

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Neutrophils induce smooth muscle hyperplasia via neutrophil elastase‐induced FGF‐2 in a mouse model of asthma with mixed inflammation2018

    • Author(s)
      Ogawa Hirohisa、Azuma Masahiko、Tsunematsu Takaaki、Morimoto Yuuki、Kondo Mayo、Tezuka Toshifumi、Nishioka Yasuhiko、Tsuneyama Koichi
    • Journal Title

      Clinical & Experimental Allergy

      Volume: 48 Pages: 1715-1725

    • DOI

      10.1111/cea.13263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Application of 2-Picolylamine Derivatized Ultra-high Performance Liquid Chromatography Tandem Mass Spectrometry for the Determination of Short-chain Fatty Acids in Feces Samples2018

    • Author(s)
      NAGATOMO Ryosuke、OKADA Yasuki、ICHIMURA Mayuko、TSUNEYAMA Koichi、INOUE Koichi
    • Journal Title

      Analytical Sciences

      Volume: 34 Issue: 9 Pages: 1031-1036

    • DOI

      10.2116/analsci.18scp10

      10.2116/analsci.18SCP10

    • NAID

      130007474699

    • ISSN
      0910-6340, 1348-2246
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Effect of coffee or coffee components on gut microbiome and short-chain fatty acids in a mouse model of metabolic syndrome2018

    • Author(s)
      Nishitsuji Kazuchika、Watanabe Syunsuke、Xiao Jinzhong、Nagatomo Ryosuke、Ogawa Hirohisa、Tsunematsu Takaaki、Umemoto Hitomi、Morimoto Yuki、Akatsu Hiroyasu、Inoue Koichi、Tsuneyama Koichi
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 16173-16173

    • DOI

      10.1038/s41598-018-34571-9

    • NAID

      120006842036

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-17K16123
  • [Journal Article] Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin2018

    • Author(s)
      Akiko Matsubara, Shingo Oda, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi
    • Journal Title

      Toxicology Letters

      Volume: 291 Pages: 184-193

    • DOI

      10.1016/j.toxlet.2018.04.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15503, KAKENHI-PROJECT-18K07069
  • [Journal Article] Aire Controls in Trans the Production of Medullary Thymic Epithelial Cells Expressing Ly-6C/Ly- 6G2018

    • Author(s)
      Morimoto Junko、Nishikawa Yumiko、Kakimoto Takumi、Furutani Kohei、Kihara Naoki、Matsumoto Minoru、Tsuneyama Koichi、Kozono Yuko、Kozono Haruo、Hozumi Katsuto、Hosomichi Kazuyoshi、Nishijima Hitoshi、Matsumoto Mitsuru
    • Journal Title

      Journal of immunology

      Volume: 201 Pages: 3244-3257

    • DOI

      10.4049/jimmunol.1800950

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08885, KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-18K19564, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06496, KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-16H05342, KAKENHI-PROJECT-17K19804
  • [Journal Article] Tissue-Resident Memory CD8+ T Cells Acting as Mediators of Salivary Gland Damage in a Murine Model of Sjogren's Syndrome2018

    • Author(s)
      Gao Cai-Yue、Yao Yuan、Li Liang、Yang Shu-Han、Chu Hui、Tsuneyama Koichi、Li Xiao-Mei、Gershwin M. Eric、Lian Zhe-Xiong
    • Journal Title

      Arthritis & Rheumatology

      Volume: 71 Pages: 121-132

    • DOI

      10.1002/art.40676

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Journal Article] Anti-drug Antibodies Against a Novel Humanized Anti-CD20 Antibody Impair Its Therapeutic Effect on Primary Biliary Cholangitis in Human CD20- and FcγR-Expressing Mice2018

    • Author(s)
      Moritoki Y, Tsuneyama K, Nakamura Y, Kikuchi K, Shiota A, Ohsugi Y, Lian ZX, Zhang W, Yang GX, Ueki S, Takeda M, Omokawa A, Saga T, Saga A, Watanabe D, Miura M, Ueno Y, Leung PSC, Tanaka A, Gershwin ME, Hirokawa M.
    • Journal Title

      Frontiers in Immunology

      Volume: 9 Pages: 2534-2534

    • DOI

      10.3389/fimmu.2018.02534

    • NAID

      120006937682

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08926, KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-15KK0329, KAKENHI-PROJECT-15K08982
  • [Journal Article] Comprehensive analysis of serum microRNAs in hapatic sinusoidal obstruction syndrome (SOS) in rats: implication as early-phase biomarkers for SOS.2018

    • Author(s)
      Takeuchi Masaki、Oda Shingo、Tsuneyama Koichi、Yokoi Tsuyoshi
    • Journal Title

      Arch. Toxicol.

      Volume: 92 Pages: 2947-2962

    • DOI

      10.1007/s00204-018-2269-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-16H02616
  • [Journal Article] Comprehensive hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice.2018

    • Author(s)
      Urano Yuya、Oda Shingo、Tsuneyama Koichi、Yokoi Tsuyoshi
    • Journal Title

      Chem. Biol. Interact.

      Volume: 296 Pages: 185-197

    • DOI

      10.1016/j.cbi.2018.09.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-16H02616
  • [Journal Article] Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury2018

    • Author(s)
      Kurano M, Tsuneyama K, Morimoto Y, Shimizu T, Jona M, Kassai H, Nakao K, Aiba A, Yatomi Y
    • Journal Title

      Thrombosis and Haemostasis

      Volume: 印刷中 Pages: 1021-1035

    • DOI

      10.1055/s-0038-1641750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K06701, KAKENHI-PROJECT-18K07069, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-16H06236
  • [Journal Article] Human β-Defensin 2 in Primary Sclerosing Cholangitis.2017

    • Author(s)
      Chang C, Lleo A, Kananurak A, Grizzi F, Tsuneyama K, Invernizzi P, Bevins CL, Bowlus CL.
    • Journal Title

      Clin Transl Gastroenterol.

      Volume: 8(3)

    • DOI

      10.1038/ctg.2017.8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Chemokine receptor CXCR3 deficiency exacerbates murine autoimmune cholangitis by promoting pathogenic CD8(+) T cell activation.2017

    • Author(s)
      Ma HD, Ma WT, Liu QZ, Zhao ZB, Liu MZ, Tsuneyama K, Gao JM, Ridgway WM, Ansari AA, Gershwin ME, Fei YY, Lian ZX.
    • Journal Title

      J Autoimmun.

      Volume: 78 Pages: 19-28

    • DOI

      10.1016/j.jaut.2016.12.012

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Prolonged activation of IL-5-producing ILC2 causes pulmonary arterial hypertrophy2017

    • Author(s)
      Ikutani M, Tsuneyama K, Kawaguchi M, Fukuoka J, Kudo F, Nakae S, Arita M, Nagai Y, Takaki S, Takatsu K.
    • Journal Title

      JCI Insight

      Volume: 2

    • DOI

      10.1172/jci.insight.90721

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-17K15739, KAKENHI-PROJECT-15K09036
  • [Journal Article] Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice.2017

    • Author(s)
      Watanabe S, Takahashi T, Ogawa H, Uehara H, Tsunematsu T, Baba H, Morimoto Y, Tsuneyama K.
    • Journal Title

      Metab. Syndr. Relat. Disord.

      Volume: 15(4) Pages: 170-177

    • DOI

      10.1089/met.2016.0114

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K15740, KAKENHI-PROJECT-15K06873
  • [Journal Article] Establishment of a mouse model of enalapril-induced liver injury and investigation of the pathogenesis2017

    • Author(s)
      Shirai Y, Oda S, Makino S, Tsuneyama K, Yokoi T.
    • Journal Title

      Lab. Invest.

      Volume: in press Pages: 545-553

    • DOI

      10.1038/labinvest.2017.22

    • NAID

      130006582043

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-16H02616
  • [Journal Article] Primary Biliary Cholangitis: Its Pathological Characteristics and Immunopathological Mechanisms2017

    • Author(s)
      Tsuneyama K, Baba H, Morimoto Y, Tsunematsu T, Ogawa H.
    • Journal Title

      The Journal of Medical Investigation

      Volume: 64 Issue: 1.2 Pages: 7-13

    • DOI

      10.2152/jmi.64.7

    • NAID

      130005501980

    • ISSN
      1343-1420, 1349-6867
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K15740
  • [Journal Article] Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice2017

    • Author(s)
      Oda S, Shirai Y, Akai S, Nakajima A, Tsuneyama K, Yokoi T.
    • Journal Title

      J. Appl. Toxicol.

      Volume: 37 Pages: 545-553

    • DOI

      10.1002/jat.3388

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-16H02616
  • [Journal Article] Kupffer cell-mediated exacerbation of methimazole-induced acute liver injury in rats.2016

    • Author(s)
      Akai S, Uematsu Y, Tsuneyama K, Oda S, Yokoi T.
    • Journal Title

      J. Appl. Toxicol

      Volume: 36 Pages: 702-705

    • DOI

      10.1002/jat.3202

    • NAID

      130005483633

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-25293037, KAKENHI-PROJECT-15K15001
  • [Journal Article] ORAL ADMINISTRATION OF a-LIPOIC ACID INCREASES SERUM LEVELS OF ASCORBIC ACID AND TOCOPHEROL: A PILOT HEMATOLOGICAL STUDY2016

    • Author(s)
      Takahashi T, Baba H, Hatta H, Ogawa H, Uehara H, Nishida Y, Kataguchi I, Tsuneyama K
    • Journal Title

      CURRENT TOPICS IN NUTRACEUTICAL RESEARCH

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.2016

    • Author(s)
      Takikawa A, Mahmood A, Nawaz A, Kado T, Okabe K, Yamamoto S, Aminuddin A, Senda S, Tsuneyama K, Ikutani M, Watanabe Y, Igarashi Y, Nagai Y, Takatsu K, Koizumi K, Imura J, Goda N, Sasahara M, Matsumoto M, Saeki K, Nakagawa T, Fujisaka S, Usui I, Tobe K.
    • Journal Title

      Diabetes

      Volume: 65 Pages: 3649-3659

    • NAID

      40021380120

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Liver disease risk of xenobiotics due to percutaneous absorption revealed by nano-PALDI imaging mass spectrometry.2016

    • Author(s)
      Taira S, Yamaguchi N, Morimoto S, Tatsuta Y, Katano H, Ichiyanagi Y, tsuneyama K, Kikuchi K.
    • Journal Title

      International Journal of recent Scientific Research

      Volume: 7(7) Pages: 12589-12592

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Deletion of SIRT1 in myeloid cells impairs glucose metabolism with enhancing inflammatory response to adipose tissue hypoxia.2016

    • Author(s)
      Akiko Takikawa, Isao Usui , Shiho Fujisaka, Masashi Ikutani, Satoko Senda, Shinpei Hattori, Koichi Tsuneyama, Yukiko Koshimizu, Ran Inoue, Ayumi Tanaka-Hayashi, Takashi Nakagawa, Yoshinori Nagai, Kiyoshi Takatsu, Toshiyasu Sasaoka, Hisashi Mori, Kazuyuki Tobe
    • Journal Title

      Diabetol Int.

      Volume: 7 Pages: 59-68

    • DOI

      10.1007/s13340-015-0213-3

    • NAID

      40020774323

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-25461333, KAKENHI-PROJECT-24689019, KAKENHI-PROJECT-26461327
  • [Journal Article] Chronic expression of interferon-gamma leads to murine autoimmune cholangitis with a female predominance.2016

    • Author(s)
      Bae HR, Leung PS, Tsuneyama K, Valencia JC, Hodge DL, Kim S, Back T, Karwan M, Merchant AS, Baba N, Feng D, Park O, Gao B, Yang GX, Gershwin ME, Young HA.
    • Journal Title

      Hepatology

      Volume: 64 Pages: 1189-201

    • DOI

      10.1002/hep.28641

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Zomepirac acyl glucuronide is responsible for zomepirac-induced acute kidney injury in mice2016

    • Author(s)
      Iwamura A, Watanabe K, Akai S, Nishinosono T, Tsuneyama K, Oda S, Kume T, Yokoi T.
    • Journal Title

      Drug Metab. Dispos.

      Volume: 44 Pages: 888-896

    • DOI

      10.1124/dmd.116.069575

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-15K15001
  • [Journal Article] Aberrant iron metabolism might have an impact on progression of diseases in Tsumura Suzuki obese diabetes mice, a model of spontaneous metabolic syndrome.2016

    • Author(s)
      Nishida T, Tsuneyama K, Fujimoto M, Nomoto K, Hayashi S, Miwa S, Nakajima T, Nakanishi Y, Hatta H, Imura J.
    • Journal Title

      Pathol Int.

      Volume: 66(11) Pages: 622-628

    • DOI

      10.1111/pin.12466

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggests malignant progression.2016

    • Author(s)
      Kawaguchi M, Hara N, Bilim V, Koike H, Suzuki M, Kim TS, Gao N, Dong Y, Zhang S, Fujinawa Y, Yamamoto O, Ito H, Tomita Y, Naruse Y, Sakamaki A, Ishii Y, Tsuneyama K, Inoue M, Itoh J, Yasuda M, Sakata N, Jung CG, Kanazawa S, Akatsu H, Minato H, Nojima T, Asai K, Miura Y.
    • Journal Title

      BMC Cancer.

      Volume: 16(1) Pages: 805-805

    • NAID

      120006814095

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Pathogenetic analyses of carbamazepine-induced liver injury in F344 rats focused on immune- and inflammation-related factors.2016

    • Author(s)
      Eita Sasaki, Azumi Iida, Shingo Oda, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakaima, and Tsuyoshi Yokoi
    • Journal Title

      Exp Toxicol Pathol.

      Volume: 68 Pages: 27-38

    • DOI

      10.1016/j.etp.2015.09.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15001, KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-25293037
  • [Journal Article] Histopaythologival characteristics of glutamine syntheses-positive hepatic tumor lesions in a mouse model of spontaneous metabolic syndrome (TSOD mouse)2016

    • Author(s)
      Takahashi T, Nishida T, Baba H, Hatta H, Imura J, Sutoh M, Toyohara S, Hokao R, Watanabe S, Ogawa H, Uehara H, Tsuneyama K
    • Journal Title

      Molecular and Clinical Oncology

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Endogenous interleukin-22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice.2016

    • Author(s)
      Yang GX, Sun Y, Tsuneyama K, Zhang W, Leung PS, He XS, Ansari AA, Bowlus C, Ridgway WM, Gershwin ME.
    • Journal Title

      Clin Exp Immunol.

      Volume: 185 Pages: 154-64

    • DOI

      10.1111/cei.12806

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism.2016

    • Author(s)
      Shohei Takai, Shingo Oda, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi.
    • Journal Title

      J Appl Toxicol.

      Volume: 36 Pages: 35-37

    • DOI

      10.1002/jat.3141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15001, KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-25293037
  • [Journal Article] Emerging of IL-33 in inflammation and immune regulation.2015

    • Author(s)
      Ikutani M, tsuneyama K, Nakae S, Takatsu K.
    • Journal Title

      Inflammation and Regeneration

      Volume: 35 Pages: 69-77

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Mammary tissue microenvironment determines T cell-dependent breast cancer-associated inflammation2015

    • Author(s)
      Takahashi K, Nagai N, Ogura K, Tsuneyama K, Saiki I, Irimura T, Hayakawa Y.
    • Journal Title

      Cancer Science

      Volume: 106 Pages: 867-874

    • DOI

      10.1111/cas.12685

    • NAID

      120006389612

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08902, KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-26670023, KAKENHI-PROJECT-15J11569, KAKENHI-PROJECT-25293011
  • [Journal Article] Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats.2015

    • Author(s)
      Iida A, Sasaki E, Yano A, Tsuneyama K, Fukami T, Nakajima M, Yokoi T.
    • Journal Title

      Drug Metab Dispos.

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Gastrointestinal Immune Response to the Shrimp Allergen Tropomyosin: Histological and Immunological Analysis in an Animal Model of Shrimp Tropomyosin Hypersensitivity.2015

    • Author(s)
      Lam YF, Tong KK, Kwan KM, Tsuneyama K, Shu SA, Leung PS, Chu KH.
    • Journal Title

      Int Arch Allergy Immunol.

      Volume: 167 Pages: 29-40

    • DOI

      10.1159/000431228

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Accumulated myeloid-derived suppressor cells demonstrate distinct phenotypes and functions in two non-alcoholic steatohepatitis mouse models.2015

    • Author(s)
      Tsunashima H, Tsuneyama K, Moritoki Y, Hara M, Kikuchi K.
    • Journal Title

      Hepatobiliary Surg Nutr.

      Volume: 4 Pages: 313-319

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] Effect of keishibukuryogan on genetic and dietary obesity models.2015

    • Author(s)
      Gao F, Yokoyama S, Fujimoto M, Tsuneyama K, Saiki I, Shimada Y, Hayakawa Y.
    • Journal Title

      Evid Based Complement Alternat Med.

      Volume: in press Pages: 801291-801291

    • DOI

      10.1155/2015/801291

    • NAID

      120006389608

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25670175, KAKENHI-PROJECT-15K08902
  • [Journal Article] Role of P450-mediated metabolism and identification of novel thiol-conjugated metabolites in mice with phenytoin-induced liver injury.2015

    • Author(s)
      Sasaki E, Iwamura A, Tsuneyama K, Fukami T, Nakajima M, Kume T, Yokoi T.
    • Journal Title

      Toxicol. Lett.

      Volume: 232 Pages: 79-88

    • DOI

      10.1016/j.toxlet.2014.10.012

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25293037, KAKENHI-PROJECT-25670175, KAKENHI-PROJECT-15K15001
  • [Journal Article] Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy.2015

    • Author(s)
      Yang JB, Wang YH, Yang W, Lu FT, Ma HD, Zhao ZB, Jia YJ, Tang W, Tsuneyama K, Ridgway WM, Gershwin ME, Lian ZX.
    • Journal Title

      J Autoimmun.

      Volume: 66 Pages: 108-117

    • DOI

      10.1016/j.jaut.2015.09.002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Journal Article] An SHR/NDmcr-cp Rat Model of Non-alcoholic steatohepatitis with advanced fibrosis induced by a High-fat, High-cholesterol Diet.2015

    • Author(s)
      Ichimura M, Hatanaka M, Tsuneyama K, Kato S, Omagari K.
    • Journal Title

      J Obes Weight Loss There

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-α-induced apoptosis by tumor-associated macrophages2015

    • Author(s)
      Kee JY, Ito A, Hojo S, Hashimoto I, Igarashi Y, Tsuneyama K, Tsukada K, Irimura T, Shibahara N, Takasaki I, Inujima A, Nakayama T, Yoshie O, Sakurai H, Saiki I, Koizumi K.
    • Journal Title

      BMC Cancer

      Volume: 14 Pages: 1471-1472

    • DOI

      10.1186/1471-2407-14-949

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24659029, KAKENHI-PROJECT-24659348, KAKENHI-PROJECT-25293011, KAKENHI-PROJECT-25670022, KAKENHI-PROJECT-25670175, KAKENHI-PROJECT-26461437
  • [Journal Article] Insight into the molecular mechanism of heme oxygenase-1 induction by docosahexaenoic acid in U937 cells.2015

    • Author(s)
      Cui ZG, Ogawa R, Tsuneyama K, Yan G, Tao L, Shimomura A, Inadera H.
    • Journal Title

      Chemico-Biological Interactions

      Volume: 238 Pages: 180-188

    • DOI

      10.1016/j.cbi.2015.07.005

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08769, KAKENHI-PROJECT-26460793, KAKENHI-PROJECT-15K15098
  • [Journal Article] igh-fat and high-cholesterol diet rapidly induces non-alcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats.2015

    • Author(s)
      Ichimura M, Kawase M, Masuzumi M, Sakaki, Nagata Y, Tanaka K, Suruga K, Tamaru S, Kato S, Tsuneyama K, Omagari K
    • Journal Title

      Hepatology Research

      Volume: 45 Pages: 458-469

    • DOI

      10.1111/hepr.12358

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J12556, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24500990, KAKENHI-PROJECT-24614011
  • [Journal Article] Immunologic potential of CTLA-4 Ig in murine autoimmune cholangitis.2015

    • Author(s)
      Tanaka H, Yang GX, Tomiyama T, Tsuneyama K, Zhang W, Leung PS, Coppel RL, Joh T, Nadler SG, Ansari AA, Bowlus C, Gershwin ME.
    • Journal Title

      Clin Exp Immunol.

      Volume: in press

    • DOI

      10.1111/cei.12581

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25670175
  • [Journal Article] Involvement of immune- and inflammatory-related factors in flucloxacillin-induced liver injury in mice.2015

    • Author(s)
      Takai S, Higuchi S, Yano A, Tsuneyama K, Fukami T, Nakajima M, Yokoi T.
    • Journal Title

      J. Appl. Toxicol.

      Volume: 35 Pages: 142-151

    • DOI

      10.1002/jat.3002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25293037, KAKENHI-PROJECT-15K15001
  • [Journal Article] A simple and rapid decalcification procedure of skeletal tissues for pathology using an ultrasonic cleaner with D-mannitol and formic acid.2014

    • Author(s)
      Hatta H, Tsuneyama K, Nomoto K, Hayashi S, Miwa S, Nakajima T, Nishida T, Nakanishi Y, Imura J.
    • Journal Title

      Acta Histochem

      Volume: in press Pages: 20-28

    • DOI

      10.1016/j.acthis.2014.01.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25460413
  • [Journal Article] Introduction and utility of liquid-based cytology on aspiration biopsy of peripheral nodular lesions of the lung.2014

    • Author(s)
      Imura J, Abe K, Uchida Y, Shibata M, Tsunematsu K, Sathoh M, Miwa S, Nakajima T, Nomoto K, Hayashi S, Tsuneyama K.
    • Journal Title

      Oncol Lett.

      Volume: 7(3) Pages: 669-673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Histopathological analysis for osteomalacia and tubulopathy in itai-itai disease.2014

    • Author(s)
      Baba H, Tsuneyama K, Kumada T, Aoshima K, Imura J.
    • Journal Title

      J Toxicol Sci.

      Volume: 39(1) Pages: 91-6

    • NAID

      130004447119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670175
  • [Journal Article] Clinicopathological analysis of CD8-positive lymphocytes in the tumor parenchyma and stroma of hepatocellular carcinoma.2014

    • Author(s)
      An JL, Ji QH, An JJ, Masuda S, Tsuneyama K.
    • Journal Title

      Oncol Lett.

      Volume: 8 Pages: 2284-2290

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Malignant transformation of hyperplastic gastric polyps: An immunohistochemical and pathological study of the changes of neoplastic phenotype.2014

    • Author(s)
      Imura J, Hayashi S, Ichikawa K, Miwa S, Nakajima T, Nomoto K, Tsuneyama K, Nogami T, Saitoh H, Fujimori T.
    • Journal Title

      Oncol Lett.

      Volume: 7 Pages: 1459-1463

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Escherichia coli infection induces autoimmune cholangitis and anti-mitochondrial antibodies in non-obese diabetic (NOD).B6 (Idd10/Idd18) mice.2014

    • Author(s)
      Wang JJ, Yang GX, Zhang WC, Lu L, Tsuneyama K, Kronenberg M, Véla JL, Lopez-Hoyos M, He XS, Ridgway WM, Leung PS, Gershwin ME
    • Journal Title

      Clin Exp Immunol.

      Volume: 175(2) Pages: 192-201

    • DOI

      10.1111/cei.12224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] A Dietary Restriction Influences the Progression But Not the Initiation of MSG-Induced Nonalcoholic Steatohepatitis.2014

    • Author(s)
      ujimoto M, Tsuneyama K, Nakanishi Y, Salunga TL, Nomoto K, Sasaki Y, Iizuka S, Nagata M, Suzuki W, Shimada T, Aburada M, Shimada Y, Gershwin ME, Selmi C.
    • Journal Title

      J Med Food.

      Volume: 17(3) Pages: 374-83

    • DOI

      10.1089/jmf.2012.0029

    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Induction of insulin secretion by apolipoprotein M, a carrier for sphingosine 1-phosphate2014

    • Author(s)
      Kurano M, Hara M, Tsuneyama K, Sakoda H, Shimizu T, Tsukamoto K, Ikeda H, Yatomi Y.
    • Journal Title

      Biochim Biophys Acta. 2

      Volume: 1841 Pages: 1217-1226

    • DOI

      10.1016/j.bbalip.2014.05.002

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25253040, KAKENHI-PROJECT-25670175, KAKENHI-PROJECT-25860740
  • [Journal Article] Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation2014

    • Author(s)
      Honda H., Nagai Y., Matsunaga T., Okamoto N., Watanabe Y., Tsuneyama K., Hayashi H., Fujii I., Ikutani M., Hirai Y., Muraguchi A., Takatsu K.
    • Journal Title

      J Leukoc Biol.

      Volume: 96 Pages: 1087-1100

    • DOI

      10.1189/jlb.3a0114-005rr

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25670175, KAKENHI-PROJECT-25870257
  • [Journal Article] Retinoid X receptor α in human liver is regulated by miR-34a.2014

    • Author(s)
      Yuki Oda, Miki Nakajima, Koichi Tsuneyama, Masataka Takamiya, Yasuhiro Aoki, Tatsuki Fukami, and Tsuyoshi Yokoi.
    • Journal Title

      Biochem Pharmacol.

      Volume: 90 Pages: 179-187

    • DOI

      10.1016/j.bcp.2014.05.002

    • NAID

      120005596359

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390039, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24659074
  • [Journal Article] Molecular mechanisms of hyperthermia-induced apoptosis enhanced by docosahexaenoic acid: implication for cancer therapy.2014

    • Author(s)
      Cui ZG, Piao JL, Kondo T, Ogawa R, Tsuneyama K, Zhao QL, Feril LB Jr, Inadera H.
    • Journal Title

      Chem Biol Interact.

      Volume: 215 Pages: 46-53

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Neonatal MSG Treatment Causes Obesity, Diabetes, and Macrovesicular Steatohepatitis with Liver Nodules in DIAR Mice.2014

    • Author(s)
      Tsuneyama K, Nishida T, Baba H, Taira S, Fujimoto M, Nomoto K, Hayashi S, Miwa S, Nakajima T, Sutoh M, Oda E, Hokao R, Imura J.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 29 Pages: 1736-1743

    • DOI

      10.1111/jgh.12610

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25460413, KAKENHI-PROJECT-25670175
  • [Journal Article] Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2Rα(-/-) mice.2014

    • Author(s)
      Yao Y, Yang W, Yang YQ, Ma HD, Lu FT, Li L, Tao YY, Tsuneyama K, Zhang W, Friedman S, Gershwin ME, Lian ZX.
    • Journal Title

      J Autoimmun.

      Volume: 51 Pages: 99-108

    • DOI

      10.1016/j.jaut.2014.02.009

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells.2014

    • Author(s)
      anaka H, Zhang W, Yang GX, Ando Y, Tomiyama T, Tsuneyama K, Leung P, Coppel RL, Ansari AA, Lian ZX, Ridgway WM, Joh T, Gershwin ME.
    • Journal Title

      Clin Exp Immunol.

      Volume: 178 Pages: 253-261

    • DOI

      10.1111/cei.12415

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Histopathological analysis for osteomalacia and tubulopathy in itai-itai disease.2014

    • Author(s)
      Baba H, Tsuneyama K, Kumada T, Aoshima K, Imura J.
    • Journal Title

      J Toxicol Sci

      Volume: 39(1) Pages: 91-6

    • NAID

      130004447119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Neonatal streptozotocin treatment causes type 1 diabetes and subsequent hepatocellular carcinoma in DIAR mice fed a normal diet.2014

    • Author(s)
      Baba H, Tsuneyama K, Nishida T, Hatta H, Nakajima T, Nomoto K, Hayashi S, Miwa S, Nakanishi Y, Hokao R, Imura J.
    • Journal Title

      Hepatology International

      Volume: 8 Pages: 415-424

    • DOI

      10.1007/s12072-014-9541-9

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Molecular mechanisms of hyperthermia-induced apoptosis enhanced by docosahexaenoic acid: implication for cancer therapy.2014

    • Author(s)
      Cui ZG, Piao JL, Kondo T, Ogawa R, Tsuneyama K, Zhao QL, Feril LB Jr, Inadera H.
    • Journal Title

      Chemico-Biological Interaction

      Volume: in press Pages: 46-53

    • DOI

      10.1016/j.cbi.2014.03.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24590743, KAKENHI-PUBLICLY-25108503, KAKENHI-PROJECT-25670175, KAKENHI-PROJECT-26460793, KAKENHI-PROJECT-26670551
  • [Journal Article] Social Isolation Stress-Induced Fear Memory Deficit is Mediated by Down-Regulated Neuro-Signaling System and Egr-1 Expression in the Brain.2014

    • Author(s)
      Okada R, Matsumoto K, Tsushima R, Fujiwara H, Tsuneyama K.
    • Journal Title

      Neurochem Res.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Animal models of primary biliary cirrhosis.2014

    • Author(s)
      Wang J, Yang GX, Tsuneyama K, Gershwin ME, Ridgway WM, Leung PS. Animal models of primary biliary cirrhosis.
    • Journal Title

      Semin Liver Dis.

      Volume: 34 Pages: 285-296

    • DOI

      10.1055/s-0034-1383728

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Splenic lymph follicles generate immunoglobulin M-producing B cells in primary biliary cirrhosis2014

    • Author(s)
      Kikuchi K, Tsuneyama K, Yamada H, Kajiyama Y, Matsumoto K, Tsunashima H, Yamashita R, Takai A, Negishi M, Hara M, Moritoki Y, Miyakawa H.
    • Journal Title

      Hepatology Research

      Volume: in press

    • DOI

      10.1111/hepr.12231

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24590952
  • [Journal Article] Differential modulation by IL-17A of Cholangitis versus Colitis in IL-2Rα deleted mice.2014

    • Author(s)
      Yang W, Yao Y, Yang YQ, Lu FT, Li L, Wang YH, Nakajima T, Tsuneyama K, Ridgway WM, Gershwin ME, Lian ZX.
    • Journal Title

      PLoS One.

      Volume: 9

    • DOI

      10.1371/journal.pone.0105351

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Changes in the expression of miRNAs at the pericentral and periportal regions of the rat liver in response to hepatocellular injury: comparison with the changes in the expression of plasma miRNAs.2014

    • Author(s)
      Yu Yamaura, Miki Nakajima, Naoyuki Tatsumi, Shingo Takagi, Tatsuki Fukami, Koichi Tsuneyama, and Tsuyoshi Yokoi.
    • Journal Title

      Toxicology.

      Volume: 322 Pages: 89-98

    • DOI

      10.1016/j.tox.2014.05.008

    • NAID

      120005596361

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390039, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24659074
  • [Journal Article] Neonatal MSG Treatment Causes Obesity, Diabetes, and Macrovesicular Steatohepatitis with Liver Nodules in DIAR Mice2014

    • Author(s)
      Tsuneyama K, Nishida T, baba H, Taira S, Fujimoto m, Nomoto K, Hayashi S, Miwa S, Nakajima T, Sutoh M, Oda M, Hokao R, Imura J.
    • Journal Title

      Journal of Gastroenterol Hepatol

      Volume: in press

    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: Implications for therapy.2014

    • Author(s)
      Yang CY, Ma X, Tsuneyama K, Huang S, Takahashi T, Chalasani NP, Bowlus CL, Yang GX, Leung PS, Ansari AA, Wu L, Coppel RL, Gershwin ME.
    • Journal Title

      Hepatology

      Volume: in press

    • DOI

      10.1002/hep.26979

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Involvement of oxidative stress and immune- and inframmation-related factors in azathioprine-induced liver injury.2014

    • Author(s)
      Matsuo K, Sasaki E, Higuchi S, Takai S, Tsuneyama K, Fukami T, Nakajima M, Yokoi T.
    • Journal Title

      Txicol. Lett

      Volume: 224(2) Pages: 215-224

    • DOI

      10.1016/j.toxlet.2013.10.025

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25293037
  • [Journal Article] Reversible phospho-Smad3 signaling between tumor-suppression and fibro-carcinogenesis in chronic hepatitis B infection2014

    • Author(s)
      10: Deng YR, Yoshida K, Jin QL, Murata M, Yamaguchi T, Tsuneyama K, Moritoki Y, Niu JQ, Matsuzaki K, Lian ZX.
    • Journal Title

      Clinical and Experimental Immunology.

      Volume: 176(1) Pages: 102-11

    • DOI

      10.1111/cei.12259

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24790724
  • [Journal Article] Social isolation-induced fear memory deficits is mediated by down-regulated neuro-signaling systems Egr-1 expression in the brain.2014

    • Author(s)
      Okada R, Matsumoto K, Tsushima R, Fujiwara H, Tsuneyama K.
    • Journal Title

      Neurochem Res

      Volume: 39 Pages: 875-882

    • DOI

      10.1007/s11064-014-1283-5

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24659347
  • [Journal Article] Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis.2013

    • Author(s)
      Kawata K, Tsuda M, Yang GX, Zhang W, Tanaka H, Tsuneyama K, Leung P, He XS, Knechtle S, Ansari AA, Coppel RL, Gershwin ME.
    • Journal Title

      PLoS One.

      Volume: 8(9)

    • DOI

      10.1371/journal.pone.0074225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Phycocyanin prevents hypertension and low serum adiponectin level in a rat model of metabolic syndrome.2013

    • Author(s)
      Ichimura M, Kato S, Tsuneyama K, et al.
    • Journal Title

      Nutrition Research

      Volume: (In press) Pages: 397-405

    • DOI

      10.1016/j.nutres.2013.03.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24614011
  • [Journal Article] Adipose tissue hypoxia induces inflammatory Ml polarity of macrophages in an HIF-la-dependent and HIF-la-independent manner in obese mice.2013

    • Author(s)
      Fujisaka S, Usui I, Ikutani M, Aminuddin A, Takikawa A, Tsuneyama K, Mahmood A, Goda N, Nagai Y, Takatsu K, Tobe K.
    • Journal Title

      Diabetologia.

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis.2013

    • Author(s)
      Dhirapong A, Yang GX, Nadler S, Zhang W, Tsuneyama K, et al.
    • Journal Title

      Hepatology.

      Volume: 57(2) Pages: 708-15

    • DOI

      10.1002/hep.26067

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Overexpression of enhancer of zeste homolog 2 and MUCl may be related to malignant behaviour in intraductal papillary neoplasm of the bile duct.2013

    • Author(s)
      Sasaki M, Matsubara T, Yoneda N, Nomoto K, Tsuneyama K, et al.
    • Journal Title

      Histopathology.

      Volume: 62(3) Pages: 446-57

    • DOI

      10.1111/his.12016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Autoimmune features in metabolic liver disease: a single-center experience and review of the literature.2013

    • Author(s)
      Tsuneyama K, Baba H, Kikuchi K, Nishida T, Nomoto K, Hayashi S, Miwa S, Nakajima T, Nakanishi Y, Masuda S, Terada M, Imura J, Selmi C.
    • Journal Title

      Clin Rev Allergy Immunol

      Volume: 45(1) Pages: 143-148

    • DOI

      10.1007/s12016-013-8383-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25460413
  • [Journal Article] Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet.2013

    • Author(s)
      Watanabe S, Tsuneyama K.
    • Journal Title

      J Toxicol Sci

      Volume: 38(3) Pages: 379-90

    • NAID

      10031158904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] A novel mouse model for phenytoin-induced liver injury: involvement of immune-related factors and P450-mediated metabolism.2013

    • Author(s)
      Sasaki E, Matsuo K, Iida A, Tsuneyama K, Fukami T, Nakajima M, Yokoi T.
    • Journal Title

      Toxicol Sci.

      Volume: 136(1) Pages: 250-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Situs inversus and cystic kidney disease: Two adult patients with this Heterogeneous syndrome.2013

    • Author(s)
      Onoe T, Konoshita T et al.
    • Journal Title

      Am J Case Rep.

      Volume: 14 Pages: 20-25

    • DOI

      10.12659/ajcr.883751

    • NAID

      120006319210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590909, KAKENHI-PROJECT-23790936, KAKENHI-PROJECT-24390181
  • [Journal Article] Induction of receptor for advanced glycation end products by insufficient leptin action triggers pancreatic β-cell failure in type 2 diabetes.2013

    • Author(s)
      Han D, Yamamoto Y, Munesue S, Motoyoshi S, Saito H, Win MT, Watanabe T, Tsuneyama K, Yamamoto H.
    • Journal Title

      Genes Cells

      Volume: 18(4) Pages: 302-14

    • DOI

      10.1111/gtc.12036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-25461335
  • [Journal Article] Spontaneous onset of nonalcoholic steatohepatitis and hepatocellular carcinoma in a mouse model of metabolic syndrome.2013

    • Author(s)
      Nishida T, Tsuneyama K, et a1.
    • Journal Title

      Lab Invest

      Volume: 93(2) Pages: 230-241

    • DOI

      10.1038/labinvest.2012.155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25460413
  • [Journal Article] Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice.2013

    • Author(s)
      Tsuda M, Zhang W, Yang GX, Tsuneyama K, e tal.
    • Journal Title

      Hepatology.

      Volume: 57(2) Pages: 806-16

    • DOI

      10.1002/hep.25829

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Endogenous acetylcholine rescues NMDA-induced long-lasting hippocampal cell damage via stimulation of muscarinic M(l) receptors : elucidation using organic hippocampal slice cultures.2013

    • Author(s)
      Inada C, Thi Le X, Tsuneyama K, et al.
    • Journal Title

      Eur J Pharmacol.

      Volume: 699(1-3) Pages: 150-9

    • DOI

      10.1016/j.ejphar.2012.11.061

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib.2013

    • Author(s)
      Deng YR, Ma HD, Tsuneyama K, Yang W, Wang YH, Lu FT, Liu CH, Liu P, He XS, Diehl AM, Gershwin ME, Lian ZX.
    • Journal Title

      J Autoimmun.

      Volume: 46 Pages: 25-34

    • DOI

      10.1016/j.jaut.2013.07.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] IFN-γ deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet.2013

    • Author(s)
      Luo XY, Takahara T, Kawai K, Fujino M, Sugiyama T, Tsuneyama K, Tsukada K, Nakae S, Zhong L, Li XK
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

      Volume: 305(12)

    • DOI

      10.1152/ajpgi.00193.2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590966, KAKENHI-PROJECT-24390181
  • [Journal Article] Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in HIF-1a-dependent and independent manners in obese mice2013

    • Author(s)
      Fujisaka S, Usui I, Ikutani M, Aminuddin A, Takikawa A, Tsuneyama K, Mahmood A, Goda N, Nagai Y, Takatsu K, Tobe K..
    • Journal Title

      Diabetologia

      Volume: 56(6) Pages: 1403-12

    • DOI

      10.1007/s00125-013-2885-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590370, KAKENHI-PUBLICLY-24117708, KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25461333
  • [Journal Article] Phosphorylated Smad2 and Smad3 signaling: Shifting between tumor suppression and fibro-carcinogenesis in chronic hepatitis C2013

    • Author(s)
      Yamaguchi T, Matsuzaki K, Inokuchi R, Kawamura R, Yoshida K, Murata M, Fujisawa J, Fukushima N, Sata M, Kage M, Nakashima O, Tamori A, Kawada N, Tsuneyama K, et al.
    • Journal Title

      Hepatology Res [Epub ahead of print]

      Volume: (In press) Pages: 1327-1342

    • DOI

      10.1111/hepr.12082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24790724, KAKENHI-PROJECT-22390153
  • [Journal Article] Studies of efficacy and liver toxicity related to adeno-associated virus-mediated RNA interference.2013

    • Author(s)
      Sun CP, Wu TH, Chen CC, Wu PY, Shih YM, Tsuneyama K, Tao MH.
    • Journal Title

      Hum Gene Ther

      Volume: 24(8) Pages: 739-50

    • DOI

      10.1089/hum.2012.239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis.2013

    • Author(s)
      Tanaka H, Yang GX, Iwakoshi N, Knechtle SJ, Kawata K, Tsuneyama K, Leung P, Coppel RL, Ansari AA, Joh T, Bowlus C, Gershwin ME.
    • Journal Title

      Clin Exp Immunol

      Volume: 174(3) Pages: 364-71

    • DOI

      10.1111/cei.12193

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet2013

    • Author(s)
      Watanabe S., Tsuneyama K.
    • Journal Title

      J. Toxicol. Sci.

      Volume: 38 Pages: 379-390

    • NAID

      10031158904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590873
  • [Journal Article] Clonality, activated antigen-specific CD8(+) T cells, and development of autoimmune cholangitis in dnTGFβRII mice.2013

    • Author(s)
      Kawata K, Yang GX, Ando Y, Tanaka H, Zhang W, Kobayashi Y, Tsuneyama K, et al.
    • Journal Title

      Hepatology

      Volume: (In press) Pages: 1094-104

    • DOI

      10.1002/hep.26418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet2013

    • Author(s)
      Watanabe S., Tsuneyama K
    • Journal Title

      J. Toxicol. Sci.

      Volume: 38 Issue: 3 Pages: 379-390

    • DOI

      10.2131/jts.38.379

    • NAID

      10031158904

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590873
  • [Journal Article] The liver in itai-itai disease (chronic cadmium poisoning): pathological features and metallothionein expression.2013

    • Author(s)
      Baba H, Tsuneyama K, et al.
    • Journal Title

      Mod Pathol.

      Volume: (In press) Pages: 1228-1234

    • DOI

      10.1038/modpathol.2013.62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-25460413, KAKENHI-PROJECT-25670175
  • [Journal Article] Pathological features of new animal models for primary biliary cirrhosis2012

    • Author(s)
      Tsuneyama K, et al.
    • Journal Title

      Int J Hepatol

      Volume: 2012 Pages: 403954-403954

    • NAID

      120004186279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Plasma cells and the chronic nonsuppurative destructive cholangitis of primary biliary cirrhosis.2012

    • Author(s)
      Takahashi T.
    • Journal Title

      Hepatology.

      Volume: 55(3) Pages: 846-55

    • DOI

      10.1002/hep.24757

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433, KAKENHI-PROJECT-24390181
  • [Journal Article] The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis.2012

    • Author(s)
      Shimoda S, Tsuneyama K, et al.
    • Journal Title

      Clin Exp Immunol

      Volume: 168(3) Pages: 279-284

    • DOI

      10.1111/j.1365-2249.2012.04581.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24591450
  • [Journal Article] Mechanism of exacebrative effect of progesterone on drug-induced liver injury2012

    • Author(s)
      Yasuyuki Toyoda, Shinya Endo, Koichi Tsuneyama, Taishi Miyashita, Azusa Yano, Tatsuki Fukami, Miki Nakajima, and Tsuyoshi Yokoi
    • Journal Title

      Toxcol. Sci.

      Volume: 126 Pages: 16-27

    • DOI

      10.1093/toxsci/kfr326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390174, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24659073
  • [Journal Article] Cattle bile but not bear bile or pig bile induces lipid profile changes and fatty liver injury in mice: mediation by cholic acid.2012

    • Author(s)
      Watanabe S., Tsuneyama K.
    • Journal Title

      J. Toxicol. Sci.

      Volume: 37 Pages: 105-121

    • NAID

      10030037499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590873
  • [Journal Article] Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis.2012

    • Author(s)
      Yu Yamaura, Miki Nakajima, Shingo Takagi, Tatsuki Fukami, Koichi Tsuneyama, and Tsuyoshi Yokoi
    • Journal Title

      PLoS One

      Volume: 7

    • DOI

      10.1371/journal.pone.0030250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390174, KAKENHI-PROJECT-24390181
  • [Journal Article] Comparative analysis of portal cell infiltrates in AMAy-positive versus AMA-negative PBC2012

    • Author(s)
      Jin Q, Moritoki Y, Lleo A, Tsuneyama K, et al.
    • Journal Title

      Hepatology

      Volume: 55(5) Pages: 1495-506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Mechanisms of the hepatoprotective effects of tamoxifen against drug-induced and chemical-induced acute liver injuries2012

    • Author(s)
      Yoshikawa Y, Miyashita T, Higuchi S, Tsuneyama K, et al.
    • Journal Title

      Toxcol. Appl. Pharmacol.

      Volume: 264(1) Pages: 42-50

    • DOI

      10.1016/j.taap.2012.06.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24659073
  • [Journal Article] Modulation of lipid metabolism with the over-expression of NPC1L1 in mice liver2012

    • Author(s)
      Kurano M. Hara M. Tsuneyama K. Okamoto K. Iso-O N. Matsushima T. Koike K. Tsukamoto K.
    • Journal Title

      J Lipid Res.

      Volume: 53 Pages: 2275-2285

    • DOI

      10.1194/jlr.m026575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591333, KAKENHI-PROJECT-24390181
  • [Journal Article] Serum soluble MD-1 levels increase with disease progression in autoimmune prone MRL/lpr-lpr mice2012

    • Author(s)
      Sasaki S.
    • Journal Title

      Mol Immunol.

      Volume: 49(4) Pages: 611-20

    • DOI

      10.1016/j.molimm.2011.10.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433, KAKENHI-PROJECT-21790463, KAKENHI-PROJECT-23659247, KAKENHI-PROJECT-24390181
  • [Journal Article] Mechanism of exacerbative effect of progesterone on drug-induced liver injury2012

    • Author(s)
      Toyoda Y, Endo S, Tsuneyama K, et al.
    • Journal Title

      Toxicol Sci

      Volume: 126(1) Pages: 16-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increases in situ expression of the apoptosis marker M30 and stem cell marker CD44.2012

    • Author(s)
      HIDEHIRO TAJIMA
    • Journal Title

      Oncol Lett.

      Volume: 3 Pages: 1186-1190

    • DOI

      10.3892/ol.2012.657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591981, KAKENHI-PROJECT-24390181
  • [Journal Article] The role of natural killer(NK) and NK T cells in the loss of tolerance in murine PBC2012

    • Author(s)
      Shimoda S, Tsuneyama K, et al.
    • Journal Title

      Clin Exp Immunol

      Volume: 168(3) Pages: 279-284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Comparative analysis of portal cell infiltrates in AMA positive versus AMA negative PBC2012

    • Author(s)
      Jin Q, Moritoki Y, Lleo A, Tsuneyama K, Invernizzi P, Moritoki H, Kikuchi K, Lian ZX, Hirschfield GM, Ansari AA, Coppel RL, Gershwin ME, Niu J
    • Journal Title

      Hepatology.

      Volume: 55 Pages: 1495-506

    • DOI

      10.1002/hep.25511

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22890024, KAKENHI-PROJECT-24390181
  • [Journal Article] Cattle bile but not bear bile or pig bile induces lipid profile changes and fatty liver injury in mice: mediation by cholic acid2012

    • Author(s)
      Watanabe S.
    • Journal Title

      J. Toxicol. Sci.

      Volume: 37(1) Issue: 1 Pages: 105-121

    • DOI

      10.2131/jts.37.105

    • NAID

      10030037499

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433, KAKENHI-PROJECT-24390181
  • [Journal Article] Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury.2012

    • Author(s)
      Satonori Higuchi, et al
    • Journal Title

      J. Appl. Toxicol.

      Volume: (in press) Pages: 815-822

    • DOI

      10.1002/jat.1706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390174, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24659073
  • [Journal Article] Pathological features of new animal models for primary biliary cirrhosis.2012

    • Author(s)
      Tsuneyama K.
    • Journal Title

      Int J Hepatol.

      Volume: 2012 Pages: 403954-403954

    • DOI

      10.1155/2012/403954

    • NAID

      120004186279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433, KAKENHI-PROJECT-24390181
  • [Journal Article] The immunobiology of colitis and cholangitis in interleukin-23pl9 and interleukin-17A deleted dominant negative form of transforming growth factor beta receptor type II mice.2012

    • Author(s)
      Ando Y, Yang GX, Tsuda M, Kawata K, Zhang W, Nakajima T, Tsuneyama K, et al.
    • Journal Title

      Hepatology.

      Volume: 56(4) Pages: 1418-26

    • DOI

      10.1002/hep.25803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Metabolic activation and inflammation reactions involved in carbamazepine-induced liver injury2012

    • Author(s)
      Higuchi S, Yano A, Takai S, Tsuneyama K, et al.
    • Journal Title

      Toxicol. Sci

      Volume: 130(1) Pages: 4-16

    • DOI

      10.1093/toxsci/kfs222

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24659073
  • [Journal Article] Study of the effects of monacolin k and other constituents of red yeast rice on obesity, insulin-resistance, hyperlipidemia, and nonalcoholic steat ohepatitis using a mouse model of metabolic syndrome.2012

    • Author(s)
      Fujimoto M, Tsuneyama K, et al.
    • Journal Title

      Evid Based Complement Alternat Med.

      Volume: 2012 Pages: 892697-892697

    • DOI

      10.1155/2012/892697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] The radioprotective 105/MD-l complex contributes to diet-induced obesity and adipose tissue inflammation.2012

    • Author(s)
      Watanabe Y, Nakamura T, Ishikawa S, Fujisaka S, Usui I, Tsuneyama K, et al.
    • Journal Title

      Diabetes.

      Volume: 61(5) Pages: 1199-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Spirulina improves non-alcoholic steatohepatitis, visceral fat macrophage aggregation, and serum leptin in a mouse model of metabolic syndrome2012

    • Author(s)
      Fujimoto M, Tsuneyama K, et al.
    • Journal Title

      Dig Liver Dis

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Immunohistochemical characteristics and malignant progression of hepatic cystic neoplasms in comparison with pancreatic counterparts.2012

    • Author(s)
      Matsubara T, Sato Y, Sasaki M, Harada K, Nomoto K, Tsuneyama K, et al.
    • Journal Title

      Hum Pathol.

      Volume: 43(12) Pages: 2177-2186

    • DOI

      10.1016/j.humpath.2012.03.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PD GF mechanisms in the brain.2012

    • Author(s)
      Zhao Q, Niu Y, Matsumoto K, Tsuneyama K, et al.
    • Journal Title

      BMC Complement Altern Med.

      Volume: 12 Pages: 188-188

    • DOI

      10.1186/1472-6882-12-188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Cattle bile but not bear bile or pig bile induces lipid profile changes and fatty liver injury in mice : mediation by cholic acid2012

    • Author(s)
      Watanabe S., Tsuneyama K.
    • Journal Title

      J. Toxicol. Sci.

      Volume: 37 Pages: 105-121

    • NAID

      10030037499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590873
  • [Journal Article] Animal models of primary biliary cirrhosis: materials and methods.2012

    • Author(s)
      Leung PS, Yang GX, Dhirapong A, Tsuneyama K, et al.
    • Journal Title

      Methods Mol Biol.

      Volume: 900 Pages: 291-316

    • DOI

      10.1007/978-1-60761-720-4_14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Deficiency in galectin-3 promotes hepatic injury in CDAA diet-induced nonalcoholic fatty liver disease.2012

    • Author(s)
      Nomoto K, Nishida T, Nakanishi Y, Fujimoto M, Takasaki I, Tabuchi Y, Tsuneyama K.
    • Journal Title

      ScientificWorldJournal.

      Volume: 2012 Pages: 22593713-22593713

    • DOI

      10.1100/2012/959824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Mass Spectrometry Imaging of the Capsaicin Localization in the Capsicum Fruits.2012

    • Author(s)
      Taira S, Shimma S, Osaka I, Kaneko D, Ichiyanagi Y, Ikeda R, Konishi-Kawamura Y, Zhu S, Tsuneyama K, Komatsu K.
    • Journal Title

      Int J Biotechnology for Wellness Industries

      Volume: (In press)

    • DOI

      10.6000/1927-3037.2012.01.01.04

    • NAID

      120004247365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Identification of innate IL-5-producing cells and their role in lung eosin ophil regulation and antitumor immunity.2012

    • Author(s)
      Ikutani M, Yanagibashi T, Ogasawara M, Tsuneyama K, et al.
    • Journal Title

      J Immunol

      Volume: 188(2) Pages: 703-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Lymphoma-like T cell infiltration in liver is associated with increased copy number of dominant negative form of TGFβreceptor II.2012

    • Author(s)
      Zhang W, Tsuda M, Yang GX, Tsuneyama K, et al.
    • Journal Title

      PLoS One.

      Volume: 7(11)

    • DOI

      10.1371/journal.pone.0049413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models2012

    • Author(s)
      Miyashita T, Toyoda Y, Tsuneyama K, et al.
    • Journal Title

      J. Toxicol. Sci.

      Volume: 37(5) Issue: 5 Pages: 931-42

    • DOI

      10.2131/jts.37.931

    • NAID

      130004447006

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Spirulina improves non-alcoholic steatohepatitis, visceral fat macrophage aggregation, and serum leptin in a mouse model of metabolic syndrome.2012

    • Author(s)
      Fujimoto M, Tsuneyama K, et al.
    • Journal Title

      Dig Liver Dis.

      Volume: 44(9) Pages: 767-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Journal Article] Estradiol and progesterone modulate halothane-induced liver injury in mice2011

    • Author(s)
      Toyoda Y, Miyashita T, Endo S, Tsuneyama K, et al.
    • Journal Title

      Toxicol Lett

      Volume: 204(1) Pages: 17-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Advantages and disadvantages of hyperbaric oxygen treatment in mice with obesity hyperlipidemia and steatohepatitis2011

    • Author(s)
      Tsuneyama K, et al.
    • Journal Title

      ScientificWorldJournal

      Volume: 11 Pages: 2124-35

    • NAID

      120005464896

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD.c3c4 model of autoimmune cholangitis.2011

    • Author(s)
      Moritoki Y, Tsuda M, Tsuneyama K, et al.
    • Journal Title

      Cell Immunol.

      Volume: 268(1) Pages: 16-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Advantages and disadvantages of hyperbaric oxygen treatment in mice with obesity hyperlipidemia and steatohepatitis.2011

    • Author(s)
      Tsuneyama K.
    • Journal Title

      Scientific WorldJournal.

      Volume: 11 Pages: 2124-2135

    • DOI

      10.1100/2011/380236

    • NAID

      120005464896

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433, KAKENHI-PROJECT-24390181
  • [Journal Article] Innate immunity and primary biliary cirrhosis : Activated invariant natural killer T cells exacerbate murine autoimmune cholangitiS and fibrosis2011

    • Author(s)
      Wu SJ, Yang YH, Tsuneyama K, et al.
    • Journal Title

      Hepatology.

      Volume: 53(3) Pages: 915-925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] B cell depletion therapy exacerbates murine PBC2011

    • Author(s)
      Dhirapong A, Lleo A, Yang GX, Tsuneyama K, et al.
    • Journal Title

      Hepatology

      Volume: 53(2) Pages: 527-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Innate immunity and primary biliary cirrhosis : activated invariantnatural killer T cells exacerbate murine autoimmune cholangitis and fibrosis2011

    • Author(s)
      Wu SJ, Yang YH, Tsuneyama K, et al.
    • Journal Title

      Hepatology

      Volume: 53(3) Pages: 915-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Septic shock is associated with receptor for advanced glycation end products ligation of LPS.2011

    • Author(s)
      Yamamoto Y, Harashima A, Saito H, Tsuneyama K, et al.
    • Journal Title

      J Immunol.

      Volume: 186(5) Pages: 3248-3257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD. c3c4 model of autoimmune cholangitis2011

    • Author(s)
      Moritoki Y, Tsuda M, Tsuneyama K, et al.
    • Journal Title

      Cell Immunol

      Volume: 268(1) Pages: 16-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] IL-4 mediates dicloxacillin-induced liver injury in mice.2011

    • Author(s)
      Higuchi S, Kobayashi M, Yoshikawa Y, Tsuneyama K, et al.
    • Journal Title

      Toxicol Lett.

      Volume: 200(3) Pages: 139-145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Application of a new histological staging and grading system for primary biliary cirrhosis to liver biopsy specimens : Interobserver agreement.2010

    • Author(s)
      Nakanuma Y, Zen Y, Harada K, Sasaki M, Nonomura A, Uehara T, Sano K, Kondo F, Fukusato T, Tsuneyama K, et al
    • Journal Title

      Pathol Int. 60(3)

      Pages: 167-174

    • NAID

      10029330966

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis2010

    • Author(s)
      Zhang W, Tsuda M, Yang GX, Tsuneyama K, et al.
    • Journal Title

      Hepatology

      Volume: 52(1) Pages: 215-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] The traditional Japanese formula keishibukuryogan reduces liver injury and inflammation in patients with nonalcoholic fatty liver disease2010

    • Author(s)
      Fujimoto M, Tsuneyama K, et al.
    • Journal Title

      Ann. N Y. Acad Sci

      Volume: 1190 Pages: 151-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] The traditional Japanese formula keishibukuryogan reduces liver injury and inflammation in patients with nonalcoholic fatty liver disease.2010

    • Author(s)
      Fujimoto M, Tsuneyama K, et al.
    • Journal Title

      Ann N Y Acad Sci. 1190(1)

      Pages: 151-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Olive leaf extract prevents spontaneous occurrence of non-alcoholic steat ohepatitis in SHR/NDmcr-cp rats.2010

    • Author(s)
      Omagari K, Kato S, Tsuneyama K, et al.
    • Journal Title

      Pathology. 42(1)

      Pages: 66-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Development of an ultrasound-emitting device for performing rapid immunostaining procedures.2010

    • Author(s)
      Hatta H, Tsuneyama K, Kondo T, Takano Y.
    • Journal Title

      J Histochem Cytochem.

      Volume: 58(5) Pages: 421-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Nutrition, geoepidemiology, and autoimmunity.2010

    • Author(s)
      Selmi C, Tsuneyama K.
    • Journal Title

      Autoimmun Rev. 9(5)

      Pages: 267-270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Usefulness of Positron Emission Tomography for management of ocular sebaceous carcinoma.2010

    • Author(s)
      Yasumura S, Shojaku H, Wada R, Watanabe Y, Shojaku H, Seto H, Kawano M, Tsuneyama K.
    • Journal Title

      Clin Nucl Med. 35(2)

      Pages: 98-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Interleukin-17 is involved in alpha-naphthylisothiocyanate-induced liver injury in mice.2010

    • Author(s)
      Kobayashi M, Higuchi S, Mizuno K, Tsuneyama K, et al.
    • Journal Title

      Toxicology.

      Volume: 10,275(1-3): Pages: 50-57

    • NAID

      130007003175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Nutrition, geoepidemiology, and autoimmunity2010

    • Author(s)
      Selmi C, Tsuneyama K.
    • Journal Title

      Autoimmun Rev

      Volume: 9(5)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Endometrioid adenocarcinoma of the vagina with a microglandular pattern arising from endometriosis after hysterectomy.2010

    • Author(s)
      Nomoto K, Hori T, Kiya C, Fukuoka J, Nakashima A, Hidaka T, Saito S, Mikami Y, Tsuneyama K, Takano Y.
    • Journal Title

      Pathol Int.

      Volume: 60(9) Pages: 636-641

    • NAID

      10031123389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] B cell depletion therapy exacerbates murine primary biliary cirrhosis.2010

    • Author(s)
      Dhirapong A, Lleo A, Yang GX, Tsuneyama K, et al.
    • Journal Title

      Hepatology.

      Volume: 53(2) Pages: 527-535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Kangen-karyu improves memory deficit caused by aging through normalization of neuro-plasticity-related signaling system and VEGF system in the brain.2010

    • Author(s)
      Zhao Q, Yokozawa T, Yamabe N, Tsuneyama K, et al.
    • Journal Title

      J Ethnopharmacol.

      Volume: 15;131(2) Pages: 377-385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Kangen-karyu improves memory deficit caused by aging through normalization of neuroplasticity-related signaling system and VEGF system in the brain2010

    • Author(s)
      Zhao Q,, Yokozawa T, Yamabe N, Tsuneyama K, Li X, Matsumoto K.
    • Journal Title

      J Ethnopharmacol. 131

      Pages: 377-385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Journal Article] Identification of candidate genes involved in endogenous protection mechanisms against acute pancreatitis in mice.2010

    • Author(s)
      Nakada S, Tsuneyama K, et al.
    • Journal Title

      Biochem Biophys Res Commun. 391(3)

      Pages: 1342-1347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Treatment of hepatocellular carcinoma with adeno-associated virus encoding interleukin-15 superagonist.2010

    • Author(s)
      Chang CM, Lo CH, Shih YM, Chen Y, Wu PY, Tsuneyama K, et al
    • Journal Title

      Hum Gene Ther. 21(5)

      Pages: 611-621

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Autoimmune Liver injury and Non-alcoholic fatty liver disease.2010

    • Author(s)
      Li J, Wang J, Tsuneyama K, Liu Y.
    • Journal Title

      Chinese J.Gastroenterol.

      Volume: 15(9) Pages: 525-527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Role of CX3CL1/fractalkine in osteoclast differentiation and bone resorption.2009

    • Author(s)
      Koizumi K, Saitoh Y, Minami T, Takeno N, Tsuneyama K, et al.
    • Journal Title

      J Immunol. 183(12)

      Pages: 7825-7831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Dose dependent development of diabetes mellitus and non-alcoholic stea tohepatitis in monosodium glutamate-induced obese mice.2009

    • Author(s)
      Sasaki Y, Suzuki W, Shimada T, Iizuka S, Nakamura S, Nagata M, Fujimoto M, Tsuneyama K, et al.
    • Journal Title

      Life Sci. 85(13-14)

      Pages: 490-498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Role of liver-infiltrating CD3+CD56+ natural killer T cells in the patho genesis of nonalcoholic fatty liver disease.2009

    • Author(s)
      Tajiri K, Shimizu Y, Tsuneyama K, et al.
    • Journal Title

      Eur J Gastroenterol Hepatol. 21(6)

      Pages: 673-680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Drug-induced hepatotoxicity test using gamma-glutamylcysteine synthetase knockdown rat.2009

    • Author(s)
      Morita M, Akai S, Hosomi H, Tsuneyama K, et al.
    • Journal Title

      Toxicol Lett. 189(2)

      Pages: 159-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Peribiliary cyst of common bile duct : possible cause of refractory jaundice.2009

    • Author(s)
      Takahashi H, Miwa S, Nomoto K, Hayashi S, Tsuneyama K, Takano Y.
    • Journal Title

      Pathol Int. 59(9)

      Pages: 692-693

    • NAID

      10027381753

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Treatment of hepatocellular carcinoma with adeno-associated virus encoding interleukin-15 superagonist.2009

    • Author(s)
      Chang CM, Lo CH, Shih YM, Chen Y, Wu PY, Tsuneyama K, et al.
    • Journal Title

      Hum Gene Ther.

      Volume: 21(5) Pages: 611-621

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] B-cell depletion with anti-CD20 ameliorates autimmune cholangitis but exacerbates colitis in transforming growth factor-beta receptor II dominant negative mice.2009

    • Author(s)
      Moritoki Y, Lian' ZX, Lindor K, Tuscano J, Tsuneyama K, et al.
    • Journal Title

      Hepatology. 50(6)

      Pages: 1893-1903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Beta-glucosylceramide ameliorates liver inflammation in murine autoimmune cholangitis2009

    • Author(s)
      Zhang W, Moritoki Y, Tsuneyama K, et al.
    • Journal Title

      Clin Exp Immunol

      Volume: 157(3) Pages: 359-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Regulatory mechanisms for adipose tissue M1 and M2 macrophges in diet-induced obese mice.2009

    • Author(s)
      Fujisaka S, Usui I, Bukhari A, Ikutani M, Oya T, Kanatani Y, Tsuneyama K, et al.
    • Journal Title

      Diabetes 58(11)

      Pages: 2574-2582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Knockdown of superoxide dismutase 2 enhances acetaminophen-induced hepatotoxicity in rat.2009

    • Author(s)
      Yoshikawa Y, Morita M, Hosomi H, Tsuneyama K, et al.
    • Journal Title

      Toxicology. 264(1-2)

      Pages: 89-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] A role for IL-17 in induction of an inflammation at the fetomaternal interface in preterm labour.2009

    • Author(s)
      Ito M, Nakashima A, Hidaka T, Okabe M, Bac ND, Ina S, Yoneda S, Shiozaki A, Sumi S, Tsuneyama K, et al.
    • Journal Title

      J Reprod Immunol. 84(1)

      Pages: 75-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] CX3CL1 (fractalkine) : a signpost for biliary in flammation in primary biliary cirrhosis.2009

    • Author(s)
      Shimoda S, Harada K, Niiro H, Taketomi A, Maehara Y, Tsuneyama K, et al.
    • Journal Title

      Hepatology. 51(2)

      Pages: 567-575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Beta-glucosylceramide ameliorates liver inflammation in murine autoim munecholangitis.2009

    • Author(s)
      Zhang W, Moritoki Y, Tsuneyama K, et al.
    • Journal Title

      Clin Exp Immunol. 157(3)

      Pages: 359-364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor beta receptor type II mice2009

    • Author(s)
      Yoshida K, Yang GX, Zhang W, Tsuda M, Tsuneyama K, et al.
    • Journal Title

      Hepatology

      Volume: 50(5) Pages: 1494-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] B-cell depletion with anti-CD20 ameliorates autoimmune cholangitis but exacerbates colitis in transforming growth factor-beta receptor II dominant negative mice2009

    • Author(s)
      Moritoki Y, Lian ZX, Lindor K, Tuscano J, Tsuneyama K, et al.
    • Journal Title

      Hepatology

      Volume: 50(6) Pages: 1893-903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Journal Article] Evidence-based efficacy of Kampo formulas in a model of non alcoholic fatty liver2008

    • Author(s)
      Fujimoto, M., Tsuneyama, K., Kainuma, M., Sekiya, N., Goto, H., Takano, Y., Terasawa, K., Selmi, C., Gershwin, ME., Shimada, Y
    • Journal Title

      Exp Biol Med(Maywood) 233(3)

      Pages: 328-37

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Journal Article] Nonalcoholic steatohepatitis and hepatocellular carcinoma in galectin-3 knockout mice2008

    • Author(s)
      Nakanishi, Y., Tsuneyama, K., Nomoto, K., Fujimoto, M., Salunga, TL., Nakajima, T., Miwa, S., Murai, Y., Hayashi, S., Kato, I., Hiraga, K., Hsu, DK., Liu, FT., Takano, Y
    • Journal Title

      Hepatol Res (In press)

    • NAID

      10023920841

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Journal Article] A possible rat model for non-alcoholic steatohepatitis: Histological findings in SHR/NDmcr-cp rats2008

    • Author(s)
      Kato, S., Omagari, K., Tsuneyama, K., Fukazawa, E., Tsukuda, H., Inohara, C., Kuroda, Y., Shiraishi, K., Mune, M
    • Journal Title

      Hepatol Res 38(7)

      Pages: 743-4

    • NAID

      10021945559

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Journal Article] Effects of a Long-Term High-Fat Diet and Switching from a High-Fat to Low-Fat, Standard Diet on Hepatic Fat Accumulation in Sprague-Dawley Rats2008

    • Author(s)
      Omagari, K., Kato, S., Tsuneyama, K., Inohara, C., Kuroda, Y., Tsukuda, H., Fukazawa, E., Shiraishi, K., Mune, M
    • Journal Title

      Dig Dis Sci

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Journal Article] Monosodium glutamate(MSG): a villain and promoter of liver inflammation and dysplasia2008

    • Author(s)
      Nakanishi, Y., Tsuneyama, K., Fujimoto, M., Salunga, TL., Nomoto, K., An, JL., Takano, Y., Iizuka, S., Nagata, M., Suzuki, W., Shimada, T., Aburada, M., Nakano, M., Selmi, C., Gershwin, ME
    • Journal Title

      J Autoimmun 30(1-2)

      Pages: 42-50

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Journal Article] Cytoplasmic fine granular expression of 8-hydroxydeoxy guanosine reflects early mitochondrial oxidative DNA damage in nonalcoholic fatty liver disease2008

    • Author(s)
      Nomoto, K., Tsuneyama, K., Takahashi, H., Murai, Y., Takano, Y
    • Journal Title

      Appl Immunohi stochem Mol Morphol 16(1)

      Pages: 71-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Journal Article] Intrahepatic cholangiocarcinoma arising in cirrhotic liver frequently expressed p63-positive basal/stem-cell phenotype2006

    • Author(s)
      Nomoto K., Tsuneyama K., et al.
    • Journal Title

      Pathol.Res.Pract. 202(2)

      Pages: 71-76

    • Data Source
      KAKENHI-PROJECT-16790223
  • [Journal Article] Cholesterol-fed rabbit as a unique model of nonalcoholic, nonobese, non-insulin-resistant fatty liver disease with characteristic fibrosis2006

    • Author(s)
      Kainuma, M., Fujimoto, M., Sekiya, N., Tsuneyama, K., Cheng, C., Takano, Y., Terasawa, K., Shimada, Y
    • Journal Title

      J Gastroenterol 41(10)

      Pages: 971-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Journal Article] Liver-Targeted and Peripheral Blood Alterations of Regulatory T cells in Primary Biliary Cirrhosis2006

    • Author(s)
      Lan RY., Tsuneyama K., et al.
    • Journal Title

      Hepatology (In press)(kakre)

    • Data Source
      KAKENHI-PROJECT-16790223
  • [Journal Article] Disrupted galectin-3 causes non-alcoholic fatty liver disease in male mice2006

    • Author(s)
      Nomoto, K., Tsuneyama, K., Abdel, Aziz, H0., Takahashi, H., Murai, Y., Cui, ZG., Fujimoto, M., Kato, I., Hiraga, K., Hsu, DK., Liu, FT., Takano, Y
    • Journal Title

      J Pathol 210(4)

      Pages: 469-77

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Journal Article] Aberrant expression of serine/threonine kinase Pim-3 in hepatocellular carcinoma development and its role in the proliferation of human hepatoma cell lines2005

    • Author(s)
      Fujii C., Tsuneyama K., et al.
    • Journal Title

      Int.J.Cancer 20;114(2)

      Pages: 209-218

    • NAID

      120000809434

    • Data Source
      KAKENHI-PROJECT-16790223
  • [Journal Article] Increased levels of chemokine receptor CXCR3 and chemokines IP-10 and MIG in atients with primary biliary cirrhosis and their first degree relatives.2005

    • Author(s)
      Chuang YH., Tsuneyama K., et al.
    • Journal Title

      J.Autoimmun. 25(2)

      Pages: 126-132

    • Data Source
      KAKENHI-PROJECT-16790223
  • [Journal Article] Expression profiling of endogenous secretory receptor for advanced glycation end products in human organs2005

    • Author(s)
      Cheng C., Tsuneyama K., et al.
    • Journal Title

      Mod.Pathol. 18(10)

      Pages: 1385-1396

    • Data Source
      KAKENHI-PROJECT-16790223
  • [Journal Article] Improved 1-h rapid immunostaining method using intermittent microwave irradiation.2004

    • Author(s)
      Kumada T., Tsuneyama K., Hatta H., Ishizawa S., Takano
    • Journal Title

      Mod.Pathol. 17

      Pages: 1141-1149

    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Improved 1-h rapid immunostaining method using intermittent microwave irradiation.2004

    • Author(s)
      Kumada T., Tsuneyama K., Hatta H., Ishizawa S, Takano Y.
    • Journal Title

      Mod.Pathol. 17

      Pages: 1141-1149

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Nuclear Galectin-3 Overexpression Inversely Correlates with Lymph Node Metastasis in Lung Adenocacinomas.2004

    • Author(s)
      Hekmat O.A.A, Hori R.Hayashi, Cheng C, Murai Y, Tsuneyama K, Matsui K, Takano Y
    • Journal Title

      Kitasato Med 33

      Pages: 299-309

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Nuclear Galectin-3 overexpression inversely correlates with lymph node metastasis in lung adenocacinomas.2004

    • Author(s)
      Hekmat O.A.A., Hori R, Hayashi S, Cheng C., Ishizawa S, Murai Y, Tsuneyama K, Matsui K, Takano Y
    • Journal Title

      Kitasato Med 33

      Pages: 299-309

    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Nuclear Galectin-3 Overexpression Inversely Correlates with Lymph Node Metastasis in Lung Adenocacinomas.2004

    • Author(s)
      Hekmat- O.A.A.Hori R, Hayashi S, Cheng C., Ishizawa S, Murai Y, Tsuneyama K, Matsui K, Takano Y.
    • Journal Title

      Kitasato Med 33

      Pages: 299-309

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Improved 1-h rapid immunostaining method using intermittent microwave irradiation.2004

    • Author(s)
      Kumada T., Tsuneyama K., Hatta H., Ishizawa S.Takano Y
    • Journal Title

      Mod.Pathol. 17

      Pages: 1141-1149

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Cytoplasmic expression of c-erbB2 in non-small lung cancers.

    • Author(s)
      Cheng C, Tsuneyama K, Matsui K, Takahashi H, Ishizawa S, Takano Y
    • Journal Title

      Virchow Arch (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] a-Tubulin nuclear overexpression is an indicator of a poor prognosis in non-Hodgkin's lymphoma patients.

    • Author(s)
      Hayashi S, Mikami T, Murai Y, Cheng C, Nakajima N, Tsuneyama K, Takano Y
    • Journal Title

      Kitasato Med (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Detection of JC virus DNA sequences in colorectal cancers in Japan.

    • Author(s)
      Hori R, Murai Y, Tsuneyama K, Hekmat OA, Nomoto K, Takahashi H, Cheng C, Kuchina T, Brian VH, Takano Y
    • Journal Title

      Virchow Arch (in press)

    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Cytoplasmic expression of c-erbB2 in non-small lung cancers.

    • Author(s)
      Cheng C, Tsuneyama K, Matsui K, Takahashi H, Ishizawa S, Takano Y
    • Journal Title

      Virchow Arch (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Correlation between DNA alteration and p53 and p16 protein expression in cancer cell lines.

    • Author(s)
      Murai Y, Hayashi S, Takahashi H, Tsuneyama K, Takano Y
    • Journal Title

      Pathol Res Prac (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Cytoplasmic expression of c-erbB2 in non-small lung cancers.

    • Author(s)
      Cheng C, Tsuneyama K, Matsui K, Takahashi H, Ishizawa S, Takano Y
    • Journal Title

      Virchow Arch (in press)

    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] α-Tubulin nuclear overexpression is an indicator of a poor prognosis in non-Hodgkin's lymphoma patients.

    • Author(s)
      Hayashi S, Mikami T, Murai Y, Cheng C, Nakajima N, Tsuneyama K, Takano Y
    • Journal Title

      Kitasato Med (in press)

    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Correlation between DNA alteration and p53 and p16 protein expression in cancer cell lines.

    • Author(s)
      Murai Y, Hayashi S, Takahashi H, Tsuneyama K, Takano Y
    • Journal Title

      Pathol Res Prac (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] α-Tubulin nuclear overexpression is an indicator of a poor prognosis in non-Hodgkin's lymphoma patients.

    • Author(s)
      Hayashi S, Mikami T, Murai Y, Cheng C, Nakajima N, Tsuneyama K, Takano Y
    • Journal Title

      Kitasato Med (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Detection of JC virus DNA sequences in colorectal cancers in Japan.

    • Author(s)
      Hori R, Murai Y, Tsuneyama K, Hekmat OA, Nomoto K, Takahashi H, Cheng C, Kuchina T, Brian VH, Takano Y
    • Journal Title

      Virchow Arch (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Correlation between DNA alteration and p53 and p16 protein expression in cancer cell lines.

    • Author(s)
      Murai Y, Hayashi S, Takahashi H, Tsuneyama K, Takano Y
    • Journal Title

      Pathol Ras Prac (in press)

    • Data Source
      KAKENHI-PROJECT-15590296
  • [Journal Article] Detection of JC virus DNA sequences in colorectal cancers in Japan.

    • Author(s)
      Hori R, Murai Y, Tsuneyama K, Hekmat OA, Nomoto K, Takahashi H, Cheng C, Kuchina T, Brian VH, Takano Y
    • Journal Title

      Virchow Arch (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590296
  • [Presentation] Torsadogenic action of late sodium current in experimental electrical storm.2021

    • Author(s)
      Tsuji Yukiomi, Tomii Naoki, Tsuneyama Koichi, Takanari Hiroki, Arafune Tatsuhiko, Niwa Ryoko, Honjo Haruo, Kodama Itsuo, Makita Naomasa, Sakuma Ichiro, Dobrev Dobromir, Nattel Stanley, Yamazaki Masatoshi.
    • Organizer
      第67回日本不整脈心電学会学術大会WEB開催
    • Data Source
      KAKENHI-PROJECT-20K08450
  • [Presentation] NASH線維化の定量的評価のための基礎的研究2020

    • Author(s)
      清水 真祐子, 富永 俊弼, 常山 幸一
    • Organizer
      日本肝臓学会大会
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 探針エレクトロスプレーイオン化質量分析(PESI-MS)の病理診断・細胞診への応用2020

    • Author(s)
      常山幸一
    • Organizer
      日本画像医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] NASH線維化肝におけるpathogen lipidsの同定2020

    • Author(s)
      市村 真祐子, 松本 穣, 尾矢 剛志, 小川 博久, 常山 幸一, 平 修
    • Organizer
      徳島医学会総会
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] Mechanisms of electrical storm: rotors anchored by enhanced NaV1.8 dependent late sodium current as a driver of Torsades de Pointes2020

    • Author(s)
      Tsuji Y, Tomii N, Tsuneyama K, Takanari H, Arafune T, Honjo H, Kodama I, Makita N, Sakuma I, Dobrev D, Nattel S, Yamazaki Mi.
    • Organizer
      Heart Rhythm Scientific Sessions 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08450
  • [Presentation] 実験的モデル動物作成に用いられる高脂肪・コレステロール食に含まれるコール酸のNASH病態形成への影響2020

    • Author(s)
      市村 真祐子, 大曲 勝久, 常山 幸一
    • Organizer
      日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] AIと光を駆使したがん細胞診断2020

    • Author(s)
      常山幸一
    • Organizer
      未来へのバイオ技術勉強会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] AIと分子病理学の新展開2020

    • Author(s)
      常山幸一
    • Organizer
      徳島医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 非アルコール性脂肪肝炎患者のリン酸化Smadによる肝発癌のリスク評価2020

    • Author(s)
      諏訪 兼彦, 山口 隆志, 吉田 勝紀, 村田 美樹, 清水 真祐子, 常山 幸一, 関 寿人, 岡崎 和一
    • Organizer
      日本肝臓学会大会
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] シェーグレン症候群と原発性胆汁性胆管炎の病理学的類似性2019

    • Author(s)
      常山幸一
    • Organizer
      第28回日本シェーグレン症候群学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 線維化組織の詳細な評価を可能にする新たなモダリティSHG2019

    • Author(s)
      常山幸一
    • Organizer
      日本法医病理学会学術全国集会
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] Pathological features of new animal models for primary biliary cholangitis2019

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      Prof.M.Eric Gershwin Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 質量分析イメージングと形態学の接点2019

    • Author(s)
      常山幸一
    • Organizer
      臨床細胞学会秋期大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 自然発症メタボリックシンドローム-NASH-HCCモデルマウスにおけるプレバイオティクスによる腸内細菌叢への介入効果の検討2019

    • Author(s)
      常山幸一
    • Organizer
      第30回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] Novel animal models for analyzing metabolic syndrome-associated liver disease2019

    • Author(s)
      常山幸一
    • Organizer
      2019 SCUT INTERNATIONAL SYMPOSIUM OF LIVER IMMUNOLOGY
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] ヒトに近い病態を示す新規NASHモデル動物の開発と応用2019

    • Author(s)
      常山幸一
    • Organizer
      日本薬学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] Development of a new diagnostic method for steatohepatitis by analysis of serum composition using atmospheric pressure mass spectrometry2019

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      PESI 研究会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] NASH周辺・関連疾患の病理2019

    • Author(s)
      常山幸一
    • Organizer
      日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 免疫チェックポイント阻害薬による肝障害を来した4例の病理学的特徴2019

    • Author(s)
      常山幸一
    • Organizer
      日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 免疫チェックポイント阻害薬による薬物性肝障害の病理2019

    • Author(s)
      常山幸一
    • Organizer
      基臨の会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 肝臓病理所見のとり方とその解釈 ~疾患モデル動物が教えてくれること~2018

    • Author(s)
      常山幸一
    • Organizer
      法医病理学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 肝腫瘍の病理学的特徴と鑑別診断:興味深い症例を中心に2018

    • Author(s)
      常山幸一
    • Organizer
      和歌山腫瘍研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] PBC animal model2018

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      The Lugano meeting
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 病理学的なものの見方・考え方のススメ ~病理・形態学をハブとした研究者ネットワークの構築とその先に~2018

    • Author(s)
      常山幸一
    • Organizer
      関東リトリート(金沢)
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] NAFLDの病理診断の動向2018

    • Author(s)
      常山幸一
    • Organizer
      日本超音波医学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07069
  • [Presentation] 新生児期ストレプトゾトシン投与4CS系マウスは通常食飼育によって持続高血糖なし に肝腫瘍を発症する2016

    • Author(s)
      常山幸一、小川博久、常松貴明、上原久典
    • Organizer
      日本病理学会総会
    • Place of Presentation
      仙台国際センター「宮城県・仙台市」
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Presentation] 異なるメカニズムに起因する新しい肝細胞癌発症モデル動物の開発と病態解析、及び治療法解明への応用2016

    • Author(s)
      常山幸一
    • Organizer
      日本病理学会秋季特別総会
    • Place of Presentation
      金沢市文化ホール「石川県・金沢市」
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Presentation] New animal models of metabolic syndrome-associated liver cancer2016

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      Kanazawa Univ. Chozen Project
    • Place of Presentation
      金沢大学角間キャンパス(石川県金沢市)
    • Year and Date
      2016-02-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Presentation] メタボリックシンドローム関連肝疾患に出現するautoimmune featuresの臨床病理学的特徴2016

    • Author(s)
      常山幸一
    • Organizer
      日本肝臓学会総会
    • Place of Presentation
      ホテルニューオータニ幕張「千葉県・千葉市」
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Presentation] TSODマウスの有する新たな可能性を探る2015

    • Author(s)
      常山幸一、渡邊俊介、高橋徹行、小川博久、上原久典、西田健志、八田秀樹、馬場逸人、井村穣二
    • Organizer
      第10回TSODマウス研究会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Year and Date
      2015-03-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] メタボリックシンドローム関連肝疾患モデル動物の開発と応用2015

    • Author(s)
      常山幸一
    • Organizer
      徳島医学会総会
    • Place of Presentation
      徳島大学医学部(徳島県徳島市)
    • Year and Date
      2015-08-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Presentation] 見えないものを“見る”技術~メタボリックシンドロームからイタイイタイ病まで~2015

    • Author(s)
      常山幸一
    • Organizer
      徳島臨床細胞学会
    • Place of Presentation
      とくしま未来健康づくり機構(徳島県徳島市)
    • Year and Date
      2015-03-05
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] 見えないものを“見る”技術~メタボリックシンドロームからイタイイタイ病まで~2015

    • Author(s)
      常山幸一
    • Organizer
      徳島臨床細胞学会
    • Place of Presentation
      とくしま未来健康づくり機構(徳島県・徳島市)
    • Year and Date
      2015-03-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670175
  • [Presentation] Nano-PALDI MSイメージングを用いた 経皮吸収の薬物動態解析2015

    • Author(s)
      山口菜月、菊池健太郎、常山幸一、森本翔大、一柳優子、片野肇、平修
    • Organizer
      第81回北陸質量分析談話会
    • Place of Presentation
      福井県立大学(福井県吉田郡永平寺町)
    • Year and Date
      2015-06-06
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Presentation] Mass spectrometric imaging of mouse livers using functional γ-Fe2O3 nanoparticles2015

    • Author(s)
      Morimoto S, Ishikawa T, Hyodo K, Yamazaki T, Taira S, Tsuneyama K, ichiyanagi Y.
    • Organizer
      Atomic Level Characterizations'2015
    • Place of Presentation
      Kunibiki Messe, Matsue, Shimane, JAPAN
    • Year and Date
      2015-10-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Presentation] Hyperinsulinemia, not hyperglycemia accelerates the progression of hepatocellular carcinoma in neonatal STZ induced mouse model2015

    • Author(s)
      Ryosuke Bessho, Masahiro Miki, Hayato Baba, Koichi Tsuneyama
    • Organizer
      American Association for the study of Liver Diseases, Annual Meeting
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2015-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Presentation] 機能化した磁性ナノ微粒子を用いたマウス肝臓質量分析イメージング2015

    • Author(s)
      森本翔大、兵藤公美典、山崎貴大、石川智也、平修、常山幸一、一柳優子
    • Organizer
      ナノ学会第13回大会
    • Place of Presentation
      東北大学片平キャンパス/片平さくらホール(宮城県仙台市)
    • Year and Date
      2015-05-11
    • Data Source
      KAKENHI-PROJECT-15K15098
  • [Presentation] マクロファージ特異的HIF-1α欠損による食餌性肥満マウスの糖代謝・脂肪組織への影響2015

    • Author(s)
      4.瀧川章子,Arshad Mahmood,Allah Nawaz,角朝信,山本誠士,常山幸一,岡部圭介,仙田聡子,中川崇,薄井勲,合田亘人,戸辺一之
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      下関市
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25461333
  • [Presentation] DIAR-MSGマウス:標準食飼育で肥満・糖尿病を経て大滴性脂肪性肝炎~肝細胞癌に至る新規モデル動物の開発2014

    • Author(s)
      常山幸一、西田健志、野本一博、林伸一、三輪重治、中島隆彦、中西ゆう子、八田秀樹、井村穣二
    • Organizer
      第1回肝臓と糖尿病代謝研究会
    • Place of Presentation
      伊藤国際学術研究センター(東京都)
    • Year and Date
      2014-07-04
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] :Frequent occurrence of both HCC and HCA in TSOD mice, which is a unique model of metabolic syndrome and non-alcoholic steatohepatitis.2014

    • Author(s)
      Koichi Tsuneyama, Takeshi Nishida, Hayato Baba, Hideki Hatta, Kazuhiro Nomoto, Takahiko Nakajima, Shinichi Hayashi, Shigeharu Miwa, Ryoji Hokao, Johji Imura
    • Organizer
      Asian Pacific Association for The Study of the Liver
    • Place of Presentation
      Brisbane、Australia
    • Data Source
      KAKENHI-PROJECT-25340121
  • [Presentation] 新生児期MSG処置DIARマウスは標準食で肥満,糖尿病,及び大滴性脂肪滴を伴うNASHを発症する2013

    • Author(s)
      18) 常山幸一,西田健志,野本一博,林伸一,三輪重治,中嶋隆彦,中西ゆう子,八田秀樹,井村穣二.
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Adipose Tissue Hypoxia Induces Inflammatory M1 Polarity of Macrophages in HIF-1a -Dependent and HIF-1a Independent Manners in Obese Mice.2013

    • Author(s)
      Fujisaka S, Usui I, Ikutani M, Aminuddin A, Takikawa A, Tsuneyama K, Mahmood A, Goda N, Nagai Y, Takatsu K, and Tobe K
    • Organizer
      The American Diabetes Association's 73rd Scientific Sessions
    • Place of Presentation
      Chicago
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461333
  • [Presentation] 新生児期STZ処置DIARマウスは標準食で1型糖尿病,肝線維化,肝細胞癌を発症する.2013

    • Author(s)
      19) 常山幸一,西田健志,野本一博,林伸一,三輪重治,中嶋隆彦,中西 ゆう子,八田 秀樹,井村穣二.
    • Organizer
      第102回日本病理 学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Neonatal MSG treatment in DIAR mice causes macrovesicular steatosis with lobular inflammation in the liver2013

    • Author(s)
      Nishida T, Tsuneyama K, et al.
    • Organizer
      2013 annual meeting, United States and Canadian Academy of Pathology
    • Place of Presentation
      Baltimore, USA
    • Year and Date
      2013-03-06
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Specific hemosiderin deposition in the spleen of TSOD mice. A unique spontaneous model showing obesity, diabetes, hyperlipidemia and steatohepatitis.2013

    • Author(s)
      Nishida T, Tsuneyama K, et al.
    • Organizer
      2013 annual meeting, United States and Canadian Academy of Pathology
    • Place of Presentation
      Baltimore, USA
    • Year and Date
      2013-03-06
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Autoimmune Features with Biliary Damages Frequently Overlapped in Old-aged Female Patients of Non-alcoholic Steatohepatitis.2013

    • Author(s)
      5) Tsuneyama K, Baba H, Nomoto K, Nishida T, Hayashi S, Miwa S, Nakajima T, Nakanishi Y, Imura J.
    • Organizer
      23rd conference of the Asia Pacific Association for the Study of the Liver (APASL)
    • Place of Presentation
      Singapole
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Myeloid cell-specific deletion of SIRT1 enhanced inflammatory response to hypoxia with glucose intolerance2013

    • Author(s)
      Akiko Takikawa, Isao Usui, Satoko Senda, Shiho Fujisaka, Yukiko Koshimizu, Koichi Tsuneyama, Amiuddin, Arshad Mahmood, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu, Hisashi Mori, Kazuyuki Tobe
    • Organizer
      The American Diabetes Association's 73rd Scientific Sessions
    • Place of Presentation
      Chicago
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461333
  • [Presentation] DIAR Mice with Neonatal MSG Treatment Showed Macrovesicular Steatosis with Lobular Inflammation and Atypical Nodules in the Liver2013

    • Author(s)
      7) Tsuneyama K, Nishida T, Nomotro K, Hayashi S, Miwa S, Nakajima T, Nakanishi Y, Sasaki Y, Nakamura S, Hokao R, Imura J.
    • Organizer
      23rd conference of the Asia Pacific Association for the Study of the Liver (APASL)
    • Place of Presentation
      Singapole
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Neonatal streptozotocin treatment in DIAR mice causes insulin-dependent diabetes mellitus and hepatocellular carcinoma by normal diet.2013

    • Author(s)
      6) Tsuneyama K, Nishida T, Fujimoto M, Hayashi S, Nomoto K, Miwa S, Nakajima T, Nakanishi Y, Sasaki Y, Nakamura S, Hokao R, Imura J.
    • Organizer
      23rd conference of the Asia Pacific Association for the Study of the Liver (APASL)
    • Place of Presentation
      Singapole
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] PBCモデルマウスと日本人留学生2012

    • Author(s)
      常山幸一
    • Organizer
      第133回肝胆膵疾患研究会
    • Place of Presentation
      神奈川(招待講演)
    • Year and Date
      2012-11-15
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] TSOD MICE: A new model of spontaneous non-alcoholic steatohepatitis and hepatocellular carcinoma based on obesity, type-2 diabetes and Hyperlipidemia.2012

    • Author(s)
      Nishida T, Fujimoto M, Tsuneyama K.
    • Organizer
      47th annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Barcelona, Spain.
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Pathological characteristics of the Iidney and bone of patients with itai-itai disease (chronic cadmium toxicity)2012

    • Author(s)
      Tsuneyama K.
    • Organizer
      101^<st> annual meeting, United States and Canadian Academy of Pathology
    • Place of Presentation
      Vancouver (Canada)
    • Year and Date
      2012-03-21
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] 牛胆は一価不飽和脂肪酸含有コレステロールエステルの優位な蓄積を伴う脂肪肝を誘導する2011

    • Author(s)
      渡辺志朗,常山幸一
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-23590873
  • [Presentation] 自然発症肥満・糖尿病・NASHモデル(TSOD)マウス脾臓における異常鉄沈着の病理組織学的検討2011

    • Author(s)
      常山幸一, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] 肝疾患モデル動物2011

    • Author(s)
      常山幸一
    • Organizer
      第4回ATBF1研究会
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] エイコサペンタエン酸がコール酸添加高脂肪食により誘導される脂肪性肝炎様症状に及ぼす影響2011

    • Author(s)
      渡辺志朗、吉田康彦、湖間戸俊輔、浜田雄大、常山幸一
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590873
  • [Presentation] Kangenkaryu, a herbal Chinese prescription, ameliorates dysfunction of central cholinergic systems in db/db mice2011

    • Author(s)
      Zhao Q., Yokozawa T., Park C.H., Tsuneyama K., Miyata T., Matsumoto K.
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] 深層水の医療分野への応用について2011

    • Author(s)
      常山幸一
    • Organizer
      環日本海機能水バイオ研究会
    • Place of Presentation
      富山(招待講演)
    • Year and Date
      2011-11-26
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] 2型糖尿病モデルマウスの認知・情動行動障害に対する漢方薬釣藤散の改善効果2010

    • Author(s)
      趙〓, 横澤隆子, 宮田健, 常山幸一, 松本欣三
    • Organizer
      第61回日本薬理学会北部会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] 自然発症肥満・糖尿病モデル(TSOD)マウスに発症ずるNASH肝腫瘍の経時的変化:病理学的解析2010

    • Author(s)
      常山幸一、藤本誠
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      山形
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] Autoimmune biliary damages and NASH2010

    • Author(s)
      Tsuneyama K
    • Organizer
      2010 Immune-Mediated Digestive Diseases Forum(招待講演)
    • Place of Presentation
      Beijing, China
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] Spirulina and its constituent phycocyanin improve visceral fat macrophage aggregation, serum adiponectin level, and stea tohepatitis in a mouse model of NAFLD associated with metabolic syndrome2010

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      第20回アジア太平洋肝臓会議
    • Place of Presentation
      北京(中国)
    • Year and Date
      2010-03-25
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] 自然発症肥満・糖尿病モデル(TSOD)マウスに発症するNASH様肝病変の発症機序の解明2010

    • Author(s)
      常山幸一, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-29
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] Pathological characterization of new animal models of Primary Biliary Cirrhosis2010

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      2010 International Seminar on Digestive Diseases
    • Place of Presentation
      北京大学人民医院
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] TSODマウスにおける異常鉄沈着の病理組織学的検討2010

    • Author(s)
      常山幸一、西田健志、藤本誠
    • Organizer
      第6回TSODマウス研究会情報交換会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-05
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] 老化促進モデルマウスSAMP8の学習記憶障害及び脳内VEGF/PDGF系障害に対する釣藤散の改善作用2010

    • Author(s)
      趙〓, 横澤隆子, 宮田健, 常山幸一, 松本欣三
    • Organizer
      第27回和漢医薬学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] Evidence-based efficacy of Chinese herbal medicine and functional foods in animal models of metabolic syndrome associated liver diseases.2010

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      The 5th Symposium of TCM Pharmaceutics of WFCMS
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] Kangen-karyu, a traditional Chinese prescription : experimental insight into its utility as an anti-dementia drug2010

    • Author(s)
      松本欣三, 趙〓, 横澤隆子, 常山幸一
    • Organizer
      The 2nd China, Japan and Korea International Conference for TCM & The 7th Sino-Russia Biomedical Forum
    • Place of Presentation
      Harbin, China(Invited)
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] Autoimmune biliary damages and NASH.2010

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      2010 Immune-Mediated Digestive Diseases Forum
    • Place of Presentation
      Bejing, China
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] メタボリック症候群関連肝疾患モデル動物を用いた和漢薬・機能性食品の効果解析と臨床への展開2010

    • Author(s)
      常山幸一
    • Organizer
      フォーラム富山「創薬」第31回研究会
    • Place of Presentation
      富山
    • Year and Date
      2010-05-18
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] Pathological characterization of new animal models of Primary Biliary Cirrhosis2010

    • Author(s)
      Tsuneyama K.
    • Organizer
      2010 International Seminar on Digestive Diseases
    • Place of Presentation
      北京(中国)
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] TSOD mouse : a new spontaneous model of nonalcoholic steatohepatitis and hepatocellular carcinoma associated with obesity, type 2 diabetes, and hyperlipidemia2010

    • Author(s)
      Tsuneyama K, et al.
    • Organizer
      第20回アジア太平洋肝臓会議
    • Place of Presentation
      北京(中国)
    • Year and Date
      2010-03-25
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] Evidence-based efficacy of Chinese herbal medicine and functional foods in animal models of metabolic syndrome associated liver diseases2010

    • Author(s)
      Tsuneyama K
    • Organizer
      The 5th Symposium of TCM Pharmaceutics of WFCMS(招待講演)
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] 自然発症肥満・糖尿病モデル(TSOD)マウスの肝病変NAFLD/NASHモデルとしての有用性2009

    • Author(s)
      常山幸一
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Year and Date
      2009-05-02
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] New Animal model of Non-alcoholic Fatty Liver Disease(NAFLD) based on Metabolic Syndrome : MSG mice & TSOD mice2009

    • Author(s)
      Tsuneyama K
    • Organizer
      Changchun international digestive disease and liver disease peak forum(招待講演)
    • Place of Presentation
      長春(中国)
    • Year and Date
      2009-05-02
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] New animal models for Non-alcoholic steatohepatitis(NASH) based on metabolic syndrome2009

    • Author(s)
      Tsuneyama K
    • Organizer
      中国消化器病学会(招待講演)
    • Place of Presentation
      広州(中国)
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] Kangenkaryu improves aging-related memory deficit by normalizing NMDA receptor-mediated signaling in the brain2009

    • Author(s)
      Matsumoto K., Zhao Q., Yokozawa T., Tsuneyama T., Tanaka K.
    • Organizer
      第1回アジア神経精神薬理学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] メタボリック症候群関連脂肪性肝炎モデルマウス(MSGマウス)におけるスピルリナの疾患予防効果2009

    • Author(s)
      常山幸一
    • Organizer
      第63回日本栄養食糧学会
    • Place of Presentation
      長崎
    • Year and Date
      2009-05-02
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] 自然発症肥満・糖尿病モデル(TSOD)マウスの肝病NAFLD/NASHモデルとしての有用性2009

    • Author(s)
      常山幸一, 他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Year and Date
      2009-05-02
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] New animal models for Non-alcoholic steatohepatitis (NASH) based on metabolic syndrome2009

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      中国消化器病学会
    • Place of Presentation
      広州(中国)
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] 慢性脳虚血マウスの空間認知障害に対する環境刺激の改善効果:VEGF及びBDNFの関与2009

    • Author(s)
      趙〓, 松本欣三, 林田未希, 常山幸一
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390197
  • [Presentation] 富山湾海洋深層水か調整した等張液による創傷治癒促進効果 in vitro study2009

    • Author(s)
      常山幸一
    • Organizer
      第11回日本褥瘡学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-09-04
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] New Animal model of Non-alcoholic Fatty Liver Disease (NAFLD) based on Metabolic Syndrome : MSG mice & TSOD mice.2009

    • Author(s)
      Koichi Tsuneyama
    • Organizer
      Changchun international digestive disease and liver disease peak forum
    • Place of Presentation
      長春(中国)
    • Year and Date
      2009-08-08
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] メタボリック症候群関連脂肪性肝炎モデルマウス(MSGマウス)を用いたカロリー制限の効果2009

    • Author(s)
      常山幸一
    • Organizer
      第45回日本肝臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] 自然発症NASH(非アルコール性脂肪性肝炎)-HCC(肝細胞癌)モデルマウスとしてのTSODマウスの有用性2009

    • Author(s)
      常山幸一
    • Organizer
      第5回TSOD(肥満・糖尿病)マウス研究会情報交換会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-06
    • Data Source
      KAKENHI-PROJECT-21590433
  • [Presentation] Monosodium glutamate injection induces a new comprehensive model of lifestyle-related non alcoholic fatty liver disease with neoplastic nodules2008

    • Author(s)
      Nakanishi, Y., Tsuneyama, K., Fujimoto, M., Salunga, TL., Nomoto, K., An, JL., Gershwin, ME
    • Organizer
      43rd Annual Meeting of the European Association for the Study of the Liver(EASL)
    • Place of Presentation
      Milan, Italy
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] 病理医からみたメタボリックシンドローム2007

    • Author(s)
      常山幸一
    • Organizer
      富山大学公開講座、「知っ得?納得!メタボリックシンドローム」
    • Place of Presentation
      富山
    • Year and Date
      2007-08-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] メタボリックシンドロームモデル動物に出現する非アルコール性脂肪性肝障害(NAFLD)の病理学的特徴2007

    • Author(s)
      常山幸一
    • Organizer
      第3回TSOD(肥満・糖尿病)マウス研究会情報交換会
    • Place of Presentation
      東京
    • Year and Date
      2007-08-10
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] 非アルコール性脂肪性肝障害(NAFLD)の病態解析と漢方方剤の効果・新規モデル動物を用いた検討.2007

    • Author(s)
      常山幸一
    • Organizer
      富山大学21世紀COEプログラムシンポジウム「東洋の知に立脚した個の医療の創生」
    • Place of Presentation
      富山
    • Year and Date
      2007-11-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] The Traditional Japanese Kampo Formula keishibukuryogan Ameliorates Steatosis, Reduces Oxidative Stress and Inflammation and Ultimately Prevents Liver Fibrosis in a Rabbit Model of Non Alcoholic Steatohepatitis2007

    • Author(s)
      Fujimoto, M., Tsuneyama, K., Kainuma, M., Sekiya, N., Goto, H., Takano, Y., Terasawa, K., Selmi, C., Gershwin, ME., Shimada, Y
    • Organizer
      The 58th Annual Meeting of The American Association for The Study of Liver Diseases
    • Place of Presentation
      Boston, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] Strategy of future food science and food business.2007

    • Author(s)
      Tsuneyama K.
    • Organizer
      21st COE seminar "Integrate of New lnsights between Western and Eastern Medicines"
    • Place of Presentation
      Davis, USA
    • Year and Date
      2007-08-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] メタボリツクシンドロームモデル動物に出現する非アルコール性脂肪性肝障害(NAFLD)の病理学的特徴2007

    • Author(s)
      常山 幸一
    • Organizer
      第3回TSOD(肥満・糖尿病)マウス研究会情報交換会
    • Place of Presentation
      東京
    • Year and Date
      2007-08-10
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] Disrupted galectin-3 causes nonalcoholic fatty liver disease in mice2006

    • Author(s)
      Tsuneyama, K., Nomoto, K., Kato, I., Hiraga, K., Takano, Y
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] Disrupted galectin-3 causes nonalcoholic fatty liver disease in mice.2006

    • Author(s)
      Tsuneyama K, et. al.
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] 非アルコール性脂肪性肝障害モデルの病態解析と漢方方剤の効果-コレステロール負荷ウサギを用いた検討-2006

    • Author(s)
      常山幸一
    • Organizer
      北里大学21世紀COEプログラム・富山大学21世紀COEプログラム「天然資源からの抗感染症薬と病態制御へのアプローチ-東洋の知と生命科学の融合-」
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590324
  • [Presentation] 隔離飼育マウス行動障害に対する酸棗仁湯の改善効果の検討

    • Author(s)
      岡田亮,藤原博典,津島遼平,李峰,常山幸一,松本欣三
    • Organizer
      第65回日本薬理学会北部会
    • Place of Presentation
      コラッセふくしま (福島)
    • Year and Date
      2014-09-26 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24659347
  • [Presentation] Daily moderate coffee intake inhibits pancreatic beta-cell damage and nonalcoholic steatohepatitis without improving obesity in a mouse model of spontaneous metabolic syndrome.

    • Author(s)
      Tsuneyama K, Baba H,Nishida T, Imura J.
    • Organizer
      24th Conference of the Asian Pacific Associaton for the Study of the Liver (APASL).
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2015-03-12 – 2015-03-15
    • Data Source
      KAKENHI-PROJECT-25340121
  • [Presentation] Nano-PALDIイメージング質量分析を用いた低分子Xenobiotics(2オクチン酸)検出法の開発

    • Author(s)
      常山幸一、菊池健太郎、守時由起、井村穣二、平修
    • Organizer
      JDDW 2014
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2014-10-23 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Nano-PALDIイメージング質量分析を用いた低分子Xenobiotics(2オクチン酸)検出法の開発

    • Author(s)
      常山幸一、菊池健太郎、守時由起、井村穣二、平修
    • Organizer
      JDDW 2014 神戸
    • Place of Presentation
      神戸国際展示場(兵庫県・神戸市)
    • Year and Date
      2014-10-23 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-25670175
  • [Presentation] Establishment of repeated liver biopsy technique in experimental mice

    • Author(s)
      Tsuneyama K, Baba H, Nakajima T, Nishida T, Imura J.
    • Organizer
      65th Annual meeting of the AASLDT,2014/11/7-11
    • Place of Presentation
      Boston (USA)
    • Year and Date
      2014-11-07 – 2014-11-11
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Establishment of repeated liver biopsy technique in experimental mice

    • Author(s)
      Tsuneyama K, Baba H, Nakajima T, Nishida T, Imura J.
    • Organizer
      65th Annual meeting of the AASLD
    • Place of Presentation
      Boston( USA)
    • Year and Date
      2014-11-07 – 2014-11-11
    • Data Source
      KAKENHI-PROJECT-25670175
  • [Presentation] Daily moderate coffee intake inhibits pancreatic beta-cell damage and nonalcoholic steatohepatitis without improving obesity in a mouse model of spontaneous metabolic syndrome

    • Author(s)
      Koichi Tsuneyama, Hayato Baba, Takeshi Nishida, Hideki Hatta, Johji Imura
    • Organizer
      The 24th Conference of the APASL
    • Place of Presentation
      Istanbul (Turkey)
    • Year and Date
      2015-03-12 – 2015-03-15
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] イタイイタイ病では骨軟化症とともに骨粗鬆症も高度に生じている

    • Author(s)
      皆川千尋、常山幸一、井村穣二
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25670175
  • [Presentation] イメージングMSの病理診断学への応用と展開

    • Author(s)
      常山 幸一、井村 穣二
    • Organizer
      第41回BMSコンファレンス
    • Place of Presentation
      能登ロイヤルホテル(石川県羽咋郡)
    • Year and Date
      2014-07-07 – 2014-07-09
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] Daily moderate coffee intake inhibits pancreatic beta-cell damage and nonalcoholic steatohepatitis without improving obesity in a mouse model of spontaneous metabolic syndrome

    • Author(s)
      Koichi Tsuneyama, Hayato Baba, Takeshi Nishida, Hideki Hatta, Johji Imura
    • Organizer
      The 24th Conference of the APASL
    • Place of Presentation
      Istanbul (Turkey)
    • Year and Date
      2015-03-12 – 2015-03-15
    • Data Source
      KAKENHI-PROJECT-25670175
  • [Presentation] イメージングMSの病理診断学への応用と展開

    • Author(s)
      常山 幸一、井村 穣二
    • Organizer
      第41回BMSコンファレンス
    • Place of Presentation
      能登ロイヤルホテル(石川県・羽咋郡)
    • Year and Date
      2014-07-07 – 2014-07-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670175
  • [Presentation] イタイイタイ病における腎病変の新たな病理学的検討

    • Author(s)
      数見友里恵、常山幸一、井村穣二
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25670175
  • [Presentation] 自然発症メタボリックシンドローム-発癌モデル(TSODマウス)の肝腫瘍の特徴

    • Author(s)
      常山 幸一、西田 健志、野本一博、林伸一、三輪重治、中嶋隆彦、八田秀樹、井村穣二
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-24390181
  • [Presentation] 隔離飼育ストレスで誘発される恐怖条件付け記憶の障害とその発症機序

    • Author(s)
      岡田亮,藤原博典,津島遼平,李峰,常山幸一,松本欣三
    • Organizer
      第64回日本薬理学会北部会
    • Place of Presentation
      旭川市大雪クリスタルホール
    • Data Source
      KAKENHI-PROJECT-24659347
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    # of Collaborated Products: 2 results
  • 124.  松崎 恒一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 125.  植木 重治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 126.  安井 武史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 127.  南川 丈夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 128.  有田 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 129.  西川 尚子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 130.  葛西 秀俊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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