hayakawa yoshihiro 早川芳弘

… Alternative Names

HAYAKAWA Yoshihiro 早川芳弘

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Researcher Number	10541956
Other IDs
Affiliation (Current)	2025: 富山大学, 学術研究部薬学・和漢系, 教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 富山大学, 学術研究部薬学・和漢系, 教授 2017 – 2019: 富山大学, 和漢医薬学総合研究所, 教授 2012 – 2016: 富山大学, 和漢医薬学総合研究所, 准教授 2014: 富山大学, 和漢医薬学総合研究所・病態生化学分野, 准教授 2011: 東京大学, 薬学研究科(研究院), 准教授 2010: The University of Tokyo, 大学院・薬学系研究科, 准教授 2009: The University of Tokyo, 大学院・薬学系研究科, 講師
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Biological pharmacy / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Tumor therapeutics / Tumor immunology Except Principal Investigator Metabolomics / Medium-sized Section 27:Chemical engineering and related fields / Basic Section 52030:Psychiatry-related / Basic Section 50010:Tumor biology-related / Basic Section 55040:Respiratory surgery-related / Basic Section 53010:Gastroenterology-related / Complex systems / Clinical oncology
Keywords	Principal Investigator NK細胞 / がん / 自然免疫 / 炎症 / がん転移 / 転移 / 腫瘍免疫応答 / がん免疫監視 / 抗腫瘍免疫応答 / 薬物治療 … More / 和漢薬 / 天然物 / 免疫 / 免疫監視 / 糖たんぱく質 / ERK / EGFR / MMP-9 / アシアロ糖蛋白質レセプター / シグナル伝達 / 糖鎖 / レクチン … More Except Principal Investigator HIF-1a / マクロファージ / 糖尿病 / 肥満 / 肝がん / smFISH法 / 光応答性材料 / がん免疫 / 細胞間相互作用 / 1細胞解析 / 脳内報酬系 / 頚部リンパ節 / 末梢リンパ球 / 薬物依存 / ドパミン神経伝達 / 不均一性 / SOX10 / 悪性黒色腫 / 癌性胸膜炎 / 胸膜播種 / VEGF / 胸腔内ガス環境 / ナノバブル / マイクロバブル / 悪性腫瘍 / 大腸 / 腸上皮幹細胞 / 腫瘍 / 大腸癌 / 小胞体 / 亜鉛トランスポーター / 腸上皮細胞 / 微量元素 / 大腸がん / 亜鉛 / Eomes / T-bet / IL-6 / 天然物 / 細胞老化 / がん予防 / NK細胞 / ケミカルバイオロジー / スクリーニング / SASP / 3　マクロファージ / 2　肥満 / 1　肝がん / 肥満症 / マウス / 腫瘍関連マクロファージ / 肝細胞がん / HIF-1 / 低酸素 / アポトーシス / 抗癌剤 / Mcl-1 / 抗癌剤耐性 / 上皮間葉転換 Less

Elucidation of the exhaustion process of NK cells in tumorPrincipal Investigator
- Principal Investigator
  
  早川芳弘
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Toyama
老化線維芽細胞制御によるがん休眠細胞の封じ込めによる骨転移治療法の開発Principal Investigator
- Principal Investigator
  
  早川芳弘
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Toyama
SOX10 regulates melanoma heterogeneity
- Principal Investigator
  
  横山悟
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  University of Toyama
Development of a Process for Integrative Single-Cell Analysis of Genes Related to Cancer Immunity
- Principal Investigator
  
  山口哲志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  Osaka University
頚部リンパ節から脳内浸潤する末梢T細胞のドパミン神経伝達に対する制御機構
- Principal Investigator
  
  泉尾直孝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  The University of Tokyo
帯電性ナノバブルによる胸膜播種抑制効果の研究
- Principal Investigator
  
  本間崇浩
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  St. Marianna University School of Medicine
  University of Toyama
Role of tissue-resident NK cells in tumor immune surveillance and their functional regulationPrincipal Investigator
- Principal Investigator
  
  早川芳弘
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Toyama
Therapeutic strategies based on the zinc transporter-mediated molecular pathology of colorectal cancer.
- Principal Investigator
  
  Ohashi Wakana
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  University of Shizuoka
  Keio University
Research of molecular-targeting prevention against inflammatory diseases using chemical biology.
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto Prefectural University of Medicine
the effects of CD206-positive macrophages on obesity-associated liver tumors
- Principal Investigator
  
  USUI ISAO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Dokkyo Medical University
  University of Toyama
Exploration of tumor-promoting inflammatory immune responses and its application for cancer treatmentPrincipal Investigator
- Principal Investigator
  
  Hayakawa Yoshihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  University of Toyama
がん悪性化に関わる炎症を制御する生理活性物質の探索Principal Investigator
- Principal Investigator
  
  早川芳弘
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Toyama
Effect of obesity and diabetes on liver cancer and tumor-associated macrophage polarization
- Principal Investigator
  
  USUI Isao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  University of Toyama
Epithelial-to-Mesenchymal Transition and Acquisition of Chemoresistance
- Principal Investigator
  
  TOGE Masayoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical oncology
- Research Institution
  University of Toyama
Investigation for NK cell subset homeostasis and function in tumor mocroenvironmentPrincipal Investigator
- Principal Investigator
  
  HAYAKAWA Yoshihiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor immunology
- Research Institution
  University of Toyama
  The University of Tokyo
Role of Asialoglycoprotein receptor in tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  HAYAKAWA Yoshihiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

[Book] 臨床免疫・アレルギー科2014
- Author(s)
  早川芳弘
- Total Pages
  4
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-26430158
[Journal Article] ネットワークにおける自然免疫の役割2022
- Author(s)
  早川芳弘
- Journal Title
  
  医学のあゆみ
  
  Volume: 281 Pages: 388-394
- Data Source
  KAKENHI-PROJECT-23K21388
[Journal Article] 自然免疫制御を介したがん免疫療法の進展　2)NK細胞昨日の制御機構とがん免疫療法への応用2022
- Author(s)
  山前結、早川芳弘
- Journal Title
  
  腫瘍内科
  
  Volume: 31 Pages: 307-312
- Data Source
  KAKENHI-PROJECT-23K21388
[Journal Article] Synthetic E-guggulsterone derivative GSD-1 inhibits NF-κB signaling and suppresses the metastatic potential of breast cancer cells2021
- Author(s)
  Abdellatef AA, Zhou Y, Yamada A, Elmekkawy SA, Kohyama A, Yokoyama S, Meselhy MR, Matsuya Y, Sakurai H, Hayakawa Y
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 140 Pages: 111737-111737
- DOI
  10.1016/j.biopha.2021.111737
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] NKG2D defines tumor‐reacting effector CD8+ T cells within tumor microenvironment2021
- Author(s)
  Mojic M, Shitaoka K, Ohshima C, Ucche S, Lyu F, Hamana H, Tahara H, Kishi H, Hayakawa Y
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 9 Pages: 3484-3490
- DOI
  10.1111/cas.15050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-21K18261
[Journal Article] Crucial contribution of GPR56/ADGRG1, expressed by breast cancer cells, to bone metastasis formation2021
- Author(s)
  Sasaki S, Zhang D, Iwabuchi S, Tanabe Y, Hashimoto S, Yamauchi A, Hayashi K, Tsuchiya H, Hayakawa Y, Baba T, Mukaida N
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 12 Pages: 4883-4893
- DOI
  10.1111/cas.15150
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-20K07567
[Journal Article] Identification of <i>Ophiocordyceps gracilioides</i> by Its Anti-tumor Effects through Targeting the NFκB-STAT3-IL-6 Inflammatory Pathway2021
- Author(s)
  Shin MK, Sasaki F, Ki DW, Win NN, Morita H, Hayakawa Y
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 5 Pages: 686-690
- DOI
  10.1248/bpb.b20-01032
- NAID
  130008033230
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-05-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus2021
- Author(s)
  Abdellatef AA, Fathy M, Mohammed AEI, Bakr MSA, Ahmed AH, Abbass HS, El-Desoky AH, Morita H, Nikaido T, Hayakawa Y
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 75 Issue: 4 Pages: 840-853
- DOI
  10.1007/s11418-021-01526-w
- NAID
  40022680983
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Anti-metastatic effects of ergosterol peroxide from the entomopathogenic fungus Ophiocordyceps gracilioides on 4T1 breast cancer cells2021
- Author(s)
  Shin MK, Sasaki F, Ki DW, Win NN, Morita H, Hayakawa Y
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 75 Issue: 4 Pages: 824-832
- DOI
  10.1007/s11418-021-01520-2
- NAID
  40022680493
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Establishment of bioluminescent imaging model using murine T cell lymphoma susceptive to NK cell-dependent immune-surveillance.2021
- Author(s)
  Fujiwara T, Miyazato K, Takahashi K, Hayakawa Y.
- Journal Title
  
  J Immunol Methods.
  
  Volume: 491 Pages: 112993-112993
- DOI
  10.1016/j.jim.2021.112993
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398
[Journal Article] SOX10 regulates melanoma immunogenicity through an IRF4-IRF1 axis2021
- Author(s)
  Yokoyama S, Takahashi A, Kikuchi R, Nishibu S, Lo JA, Hejna M, Moon WM, Kato S, Zhou Y, Hodi FS, Song JS, Sakurai H, Fisher DE, Hayakawa Y
- Journal Title
  
  Cancer Research
  
  Volume: 81 Issue: 24 Pages: 6131-6141
- DOI
  10.1158/0008-5472.can-21-2078
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Design and synthesis of 2-substituted-4-benzyl-5-methylimidazoles as new potential anti-breast cancer agents to inhibit oncogenic STAT3 functions2021
- Author(s)
  Beshay BY, Abdellatef AA, Loksha YM, Fahmy SM, Habib NS, Bekhit AEA, Georghiou PE, Hayakawa Y, Bekhit AA
- Journal Title
  
  Bioorganic Chemistry
  
  Volume: 113 Pages: 105033-105033
- DOI
  10.1016/j.bioorg.2021.105033
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Flavanols and flavanes from Crinum asiaticum and their effects on LPS signaling pathway through the inhibition of NF-κB activation2021
- Author(s)
  Do KM, Shin MK, Kodama T, Win NN, Prema P, Nguyen HM, Hayakawa Y, Morita H
- Journal Title
  
  Planta Medica
  
  Volume: - Issue: 11 Pages: 913-920
- DOI
  10.1055/a-1585-5877
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Anti-inflammatory effects of Morus alba Linne bark on the activation of toll-like receptors and imiquimod-induced ear edema in mice2021
- Author(s)
  Umeyama L, Hardianti B, Kasahara S, Dibwe DF, Awale S, Yokoyama S, Hayakawa Y
- Journal Title
  
  BMC Complementary Medicine and Therapies
  
  Volume: 21 Issue: 1
- DOI
  10.1186/s12906-021-03291-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Anti‑inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway.2020
- Author(s)
  Hardianti B, Umeyama L, Li F, Yokoyama S, Hayakawa Y.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 22 Issue: 6 Pages: 5385-5391
- DOI
  10.3892/mmr.2020.11615
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-18K07227
[Journal Article] Anti-Metastatic Effects of Curcumin Analogues in a Mouse Breast Cancer Model2020
- Author(s)
  Ucche S, Murwanti R, Ritmaleni, Hayakawa Y.
- Journal Title
  
  BPB Reports
  
  Volume: 3 Issue: 2 Pages: 76-79
- DOI
  10.1248/bpbreports.3.2_76
- NAID
  130007944871
- ISSN
  2434-432X
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398
[Journal Article] Pharmacological targeting of natural killer cells for cancer immunotherapy.2020
- Author(s)
  Miyazato K, Hayakawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 6 Pages: 1869-1875
- DOI
  10.1111/cas.14418
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398
[Journal Article] Antimetastatic effects of thalidomide by inducing the functional maturation of peripheral natural killer cells2020
- Author(s)
  Miyazato K, Tahara H, Hayakawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 8 Pages: 2770-2778
- DOI
  10.1111/cas.14538
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398
[Journal Article] Anti-metastatic Effects of Baicalein by Targeting STAT3 Activity in Breast Cancer Cells2020
- Author(s)
  Susmitha Gorrepotu D, Miyazato K, Ogura K, Yokoyama S, Hayakawa Y.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 12 Pages: 1899-1905
- DOI
  10.1248/bpb.b20-00571
- NAID
  130007948716
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-12-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-18K07227
[Journal Article] Anti-inflammatory activities of isopimara-8(9),15-diene diterpenoids and mode of action of kaempulchraols B-D from Kaempferia pulchra rhizomes2020
- Author(s)
  N.N. Win, B. Hardianti, H. Ngwe, Y. Hayakawa, H. Morita
- Journal Title
  
  J Nat Med
  
  Volume: 74 Issue: 2 Pages: 487-494
- DOI
  10.1007/s11418-020-01389-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23794, KAKENHI-PLANNED-17H06398, KAKENHI-PUBLICLY-19H04649
[Journal Article] Anti-inflammatory effect of fermented brown rice and rice bran with Aspergillus oryzae on mice.2020
- Author(s)
  Umeyama L, Kasahara S, Sugawara M, Yokoyama S, Saiki I, Hayakawa Y.
- Journal Title
  
  Traditional & Kampo Medicine.
  
  Volume: 8 Issue: 1 Pages: 60-65
- DOI
  10.1002/tkm2.1270
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398
[Journal Article] Anti-inflammatory activities of isopimara-8(14),-15-diene diterpenoids and mode of action of kaempulchraols P and Q from Kaempferia pulchra rhizomes2020
- Author(s)
  Nwet WN, Hardianti B, Kasahara S, Ngwe H, Hayakawa Y, Morita H.
- Journal Title
  
  Bioorg Med Chem.
  
  Volume: 30 Issue: 2 Pages: 126841-126841
- DOI
  10.1016/j.bmcl.2019.126841
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PUBLICLY-19H04649
[Journal Article] Molecular mechanisms of natural compounds in cell death induction and sensitization to chemotherapeutic drugs in lung cancer.2019
- Author(s)
  Wattanathamsan O, Hayakawa Y, Pongrakhananon V.
- Journal Title
  
  Phytother Res.
  
  Volume: 33 Issue: 10 Pages: 2531-2547
- DOI
  10.1002/ptr.6422
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Rational Combination Therapy for Melanoma with Dinaciclib by Targeting BAK-Dependent Cell Death2019
- Author(s)
  Xu Xiaoou、Eshima Shizuka、Kato Shinichiro、Fisher David E.、Sakurai Hiroaki、Hayakawa Yoshihiro、Yokoyama Satoru
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 19 Issue: 2 Pages: 627-636
- DOI
  10.1158/1535-7163.mct-19-0451
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07227, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H03368
[Journal Article] Macrophage‐specific hypoxia‐inducible factor‐1α deletion suppresses the development of liver tumors in high‐fat diet‐fed obese and diabetic mice2019
- Author(s)
  Takikawa Akiko、Usui Isao、Fujisaka Shiho、Tsuneyama Koichi、Okabe Keisuke、Nakagawa Takashi、Nawaz Allah、Kado Tomonobu、Jojima Teruo、Aso Yoshimasa、Hayakawa Yoshihiro、Yagi Kunikimi、Tobe Kazuyuki
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press Issue: 6 Pages: 1-8
- DOI
  10.1111/jdi.13047
- NAID
  120006980551
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-18K16193, KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-17K16143, KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204, KAKENHI-PLANNED-17H06398
[Journal Article] NK Cells Control Tumor-Promoting Function of Neutrophils in Mice2018
- Author(s)
  Ogura K, Sato-Matsushita M, Yamamoto S, Hori T, Sasahara M, Iwakura Y, Saiki I, Tahara H, Hayakawa Y
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 印刷中 Issue: 3 Pages: 348-357
- DOI
  10.1158/2326-6066.cir-17-0204
- NAID
  120006402039
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-15K08902, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045
[Journal Article] Lung-resident natural killer cells control pulmonary tumor growth in mice2018
- Author(s)
  Yamamoto Yutaka、Miyazato Kiho、Takahashi Kei、Yoshimura Naoki、Tahara Hideaki、Hayakawa Yoshihiro
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 9 Pages: 2670-2676
- DOI
  10.1111/cas.13703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398
[Journal Article] The Dark Side of IFN-g: Its Role in Promoting Cancer Immunoevasion.2017
- Author(s)
  Mojic M, Takeda K, Hayakawa Y.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 28 Issue: 1 Pages: 1-13
- DOI
  10.3390/ijms19010089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398
[Journal Article] IL-17A-producing CD30(+) Vδ1 T cells drive inflammation-induced cancer progression.2016
- Author(s)
  Kimura Y, Nagai N, Tsunekawa N, Sato-Matsushita M, Yoshimoto T, Cua DJ, Iwakura Y, Yagita H, Okada F, Tahara H, Saiki I, Irimura T, Hayakawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 9 Pages: 1206-14
- DOI
  10.1111/cas.13005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15J11569, KAKENHI-PROJECT-25293011, KAKENHI-PROJECT-26290059, KAKENHI-PROJECT-26430158, KAKENHI-PROJECT-26460472, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-15K08902, KAKENHI-PROJECT-26670023
[Journal Article] Functional roles of tumor necrosis factor-related apoptosis-inducing ligand-DR5 interaction in B16F10 cells by activating the nuclear factor-KB pathway to induce metastatic potential2013
- Author(s)
  Kei Takahashi, Kazuyoshi Takeda, Ikuo Saiki, Tatsuro Irimura and Yoshihiro Hayakawa
- Journal Title
  
  Cancer Science
  
  Volume: 104 Issue: 5 Pages: 558-562
- DOI
  10.1111/cas.12112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10991, KAKENHI-PROJECT-21390018, KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-23701073, KAKENHI-PROJECT-24659029, KAKENHI-PROJECT-24659348, KAKENHI-PROJECT-25293011
[Journal Article] Identification of plant extracts sensitizing breast cancer cells to TRAIL.2013
- Author(s)
  Abdelhamed S, Yokoyama S, Hafiyani L, Kalauni SK, Hayakawa Y, Awale S, Saiki I.
- Journal Title
  
  Oncology Reports
  
  Volume: 29 Issue: 5 Pages: 1991-1998
- DOI
  10.3892/or.2013.2293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701073, KAKENHI-PROJECT-24659348, KAKENHI-PROJECT-24700971
[Journal Article] Targeting NKG2D in tumor surveillance.2012
- Author(s)
  Hayakawa Y.
- Journal Title
  
  Expert Opinon on Therapeutic Targets
  
  Volume: 16 Issue: 6 Pages: 587-599
- DOI
  10.1517/14728222.2012.681378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701073
[Journal Article] Early activation and interferon-Y production of tumor-infiltrating mature CD27 high natural killer cells2011
- Author(s)
  Y.Hayakawa
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 11 Pages: 1967-1971
- DOI
  10.1111/j.1349-7006.2011.02042.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-22659016, KAKENHI-PUBLICLY-23112519, KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-23701073
[Journal Article] IFN-γ production by lung NK cells is sritical for the natural resistance to pulumonary metastasis of B16 melanoma in mice2011
- Author(s)
  Takeda, K., Nakayama, M., et al
- Journal Title
  
  J.Leukoc.Biol.
  
  Volume: 90 Issue: 4 Pages: 777-785
- DOI
  10.1189/jlb.0411208
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112519, KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23701073
[Journal Article] Asialoglycoprotein Receptor Promotes Cancer Metastasis by Activating the EGFR-ERK Pathway.2011
- Author(s)
  Ueno S, Mojic M, Ohashi Y, Higashi N , Hayakawa Y*, Irimura T*.
- Journal Title
  
  Cancer Res
  
  Volume: 71(20) Issue: 20 Pages: 6419-27
- DOI
  10.1158/0008-5472.can-11-1773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701073
[Journal Article] The Interactions of Multiple Cytokines Control NK Cell Maturation.2010
- Author(s)
  Brady J, Carotta S, Thong RR, Chan CJ, Hayakawa Y, Smyth MJ, Nutt SL.
- Journal Title
  
  The Journai of Immunology
  
  Volume: 185 Pages: 6679-6688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules.2010
- Author(s)
  Takeda K, Kojima Y, Uno T, Hayakawa Y, Teng MW, Yoshizawa H, Yagita H, Gejyo F, Okumura K, Smyth MJ
- Journal Title
  
  The Journal of Immunology 184
  
  Pages: 5439-5501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] The Interactions of Multiple Cytokines Control NK Cell Maturation.2010
- Author(s)
  Brady J, Carotta S, Thong RP, Chan CJ, Hayakawa Y, Smyth MJ, Nutt SL
- Journal Title
  
  The Journal of Immunology 185
  
  Pages: 6679-6688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] Subset analysis of human and mouse mature NK cells.2010
- Author(s)
  Hayakawa Y, Andrews DM, Smyth MJ.
- Journal Title
  
  Methods Mol Biol. 612
  
  Pages: 27-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] In vivo imaging of obesity-induced inflammation in adipose tissue.2010
- Author(s)
  Fushiki H, Hayakawa Y, Gomori A, Seo T, Tewari S, Ozaki S, Yoshimoto R.
- Journal Title
  
  Biochem Biophys Res Commun. 391
  
  Pages: 674-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] Subset analysis of human and mouse mature NK cells.2010
- Author(s)
  Hayakawa Y, Andrews DM, Smyth MJ
- Journal Title
  
  Methods Mol.Biol. 612
  
  Pages: 27-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules.2010
- Author(s)
  Takeda K, Kojima Y, Uno T, Hayakawa Y, Teng MW, Yoshizawa H, Yagita H, Gejyo F. Okumura K, Smyth MJ.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 184 Pages: 5439-5501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] In vivo imaging of obesity-induced inflammation in adipose tissue.2009
- Author(s)
  Fushiki H, Hayakawa Y, Gomori A, Seo T, Tewari S, Ozaki S, Yoshimoto R
- Journal Title
  
  Biochem Biophys Res Commun. 391
  
  Pages: 674-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] Quantification of mouse pulmonary cancer models by microcomputed to mography imaging.2009
- Author(s)
  Fushiki H, Kanoh-Azuma T, Katoh M, Kawabata K, Jiang J, Tsuchiya N, Satow A, Tamai Y, Hayakawa Y.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1544-1559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] Quantification of mouse pulmonary cancer models by microcomputed tomography imaging.2009
- Author(s)
  Fushiki H, Kanoh-Azuma T, Katoh M, Kawabata K, Jiang J, Tsuchiya N, Satow A, Tamai Y, Hayakawa Y
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1544-1559
- NAID
  10027193794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] Reduction of autofluorescence of in vivo fluorescence imaging by using purified diet.2009
- Author(s)
  Fushiki H, Hayakawa Y
- Journal Title
  
  Nippon Yakurigaku Zasshi 134
  
  Pages: 13-16
- NAID
  10025741057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Journal Article] Reduction of autofluorescence of in vivo fluorescence imaging by using purified diet.2009
- Author(s)
  Fushiki H, Hayakawa Y.
- Journal Title
  
  Nippon Yakurigaku Zasshi. 134
  
  Pages: 13-16
- NAID
  10025741057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Identification of the origin of Amomi semen species with NK cell immunomodulatory activities2024
- Author(s)
  Yoshimasa Yamamoto, Yoshihiro Hayakawa
- Organizer
  The 1st International Symposium on Cancer Immunology and Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] NK細胞の抗腫瘍エフェクター機能の制御メカニズム2023
- Author(s)
  早川芳弘
- Organizer
  第20回日本免疫治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Therapeutic targeting of NK cell anti-tumor effector function through the blockade of homeostatic self-MHC-I recognition2023
- Author(s)
  He Ka, Yui Yamamae, So-Ichiro Sasaki, Yoshihiro Hayakawa
- Organizer
  2nd JCA-AACR Precision Cancer Medicine Internatonal Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] PP2A negatively regulates NK cell T-bet expression and effector function2023
- Author(s)
  Yui Yamamae, Daisuke Hara, Manabu Kawada, Yoshihiro Hayakawa
- Organizer
  The 20th Meeting of the Society for Natural Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] PP2AはmTOR-T-bet経路を介してNK細胞の抗転移エフェクター機能を制御する2023
- Author(s)
  山前結，原大輔，川田学，早川芳弘
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Role of homeostatic MHC Class I recognition in regulating anti-tumor effector function of mature NK cell2023
- Author(s)
  Ka He, Yui Yamamae, Soichiro Sasaki, Yoshihiro Hayakawa
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] NK細胞の抗転移エフェクター機能における恒常的MHC-I認識の役割2023
- Author(s)
  He Ka, 山前結，佐々木宗一郎，早川芳弘
- Organizer
  第32回日本がん転移学会学術総会・総会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] NK細胞によるがん転移の組織別制御機構2023
- Author(s)
  原大輔，山本奨也，山前結，佐々木宗一郎，早川芳弘
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] PP2AはNK細胞の抗腫瘍エフェクター機能を抑制的に制御するNK細胞によるがん転移の組織別制御機構2023
- Author(s)
  山前結，原大輔，川田学，早川芳弘
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Protein phosphatase 2A regulates NK cell effector function through mTOR pathway2022
- Author(s)
  山前結，早川芳弘
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Role of homeostatic MHC classⅠrecognition in regulating the function of mature tissue-resident NK cells2022
- Author(s)
  Ka He, 山前結，佐々木宗一郎，田原秀晃，早川芳弘
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] 和漢薬による抗腫瘍免疫応答の調節2022
- Author(s)
  早川芳弘
- Organizer
  第39回和漢医薬学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Role of homeostatic MHC classⅠrecognition in regulating anti-tumor effector function of NK cells2022
- Author(s)
  Ka He, 山前結，佐々木宗一郎，田原秀晃，早川芳弘
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Understanding host defense system and its application to drug discovery2022
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  International Conference and Exhibition Pharmaceutical Sciences and Technology 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] NK細胞の抗腫瘍エフェクター機能の制御メカニズム解明2022
- Author(s)
  早川芳弘
- Organizer
  第26回日本がん免疫学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Identification of PP2A as an intrinsic checkpoint of T-bet and anti-tumor effector function of NK cells2022
- Author(s)
  山前結，川田学，早川芳弘
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] MHCクラスⅠ阻害はNK細胞による転移抑制作用を増強する2022
- Author(s)
  Ka He, 早川芳弘
- Organizer
  第31回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Regulatory role of Protein phosphatase 2A on T-bet expression and effector function of NK cell2021
- Author(s)
  山前結，早川芳弘
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] タンパク質脱リン酸化酵素PP2AによるNK細胞のエフェクター機能抑制の解析2021
- Author(s)
  山前結，原大輔，新宮領勇輝，宮里紀穂，川田学，早川芳弘
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Immuno-regulatory role of PP2A on anti-tumor effector function of NK cells2021
- Author(s)
  山前結，川田学，早川芳弘
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Paradoxical roles of host immunity in controlling tumor progression and metastasis2021
- Author(s)
  早川芳弘, 竹田和由
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Role of MHC class I recognition in regulating anti-tumor effector function of lung-tissue resident mature NK cell2021
- Author(s)
  Ka He, Yui Yamamae, Hideaki Tahara, Yoshihiro Hayakawa
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Immuno-regulatory role of PP2A on anti-tumor effector function of NK cells2021
- Author(s)
  山前結，川田学，早川芳弘
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Acquired resistance mechanism of cancer cells to anti-tumor immunity2021
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  The 27th International Symposium on Molecular Cell Biology of Macrophages
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Protein Phosphatase 2A によるNK 細胞の抗腫瘍エフェクター機能制御2021
- Author(s)
  山前結，原大輔，新宮領勇輝，宮里紀穂，川田学，早川芳弘
- Organizer
  第30 回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-23K21388
[Presentation] Role of MHC class I recognition in regulating anti-tumor effector function of lung-tissue resident mature NK cell2021
- Author(s)
  Ka He, Yui Yamamae, Hideaki Tahara, Yoshihiro Hayakawa.
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] がん細胞の免疫適応機構に関わる分子探索研究2021
- Author(s)
  早川芳弘
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 健康長寿社会の実現に向けた生体防御システムの理解と和漢薬の可能性2021
- Author(s)
  早川芳弘
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Role of NK cells in controlling cancer growth and metastasis2019
- Author(s)
  早川芳弘
- Organizer
  The 6th ICPAPS and The 3rd ASEAN PharmNET 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] NK細胞の多様性とがん免疫応答における役割2019
- Author(s)
  早川芳弘
- Organizer
  第105回日本消化器病学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Pre-clinical animal models for studying cancer immunology2019
- Author(s)
  早川芳弘
- Organizer
  1st Preclinical Toxicity and Efficacy Assessment of Medicines and Chemicals Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Role of NK cells in controlling cancer growth and metastasis2019
- Author(s)
  早川芳弘
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Targeting natural killer cells to regulate cancer-associated inflammation2018
- Author(s)
  Hayakawa Y
- Organizer
  1st International Seminar on Pharmaceutical 2018; Manado, Indonesia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Targeting inflammatory tumor microenvironment for developing new cancer treatment2018
- Author(s)
  Hayakawa Y
- Organizer
  The Third International Symposium on Toyama-Asia-Africa Pharmaceutical Network; Toyama
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Anti-metastatic effect of immunomodulatory drugs (IMiDs) through the regulation of NK cell homeostasis2017
- Author(s)
  Miyazato K, Tahara H, Hayakawa Y
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society (ICIS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] NK cells control tumor-promoting function of neutrophils2017
- Author(s)
  Ogura K, Sato-Matsushita M, Hori T, Iwakura Y, Tahara H, Saiki I, Hayakawa Y
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society (ICIS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Targeting innate lymphocytes to regulate cancer-associated inflammation2016
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26430158
[Presentation] 自然リンパ球をターゲットとしたがん関連炎症の制御2016
- Author(s)
  早川芳弘
- Organizer
  第25回日本がん転移学会学術集会・総会
- Place of Presentation
  米子コンベンションセンター
- Year and Date
  2016-07-21
- Invited
- Data Source
  KAKENHI-PROJECT-26430158
[Presentation] Vd1 T細胞を起点とする炎症によるがん悪性化メカニズムの理解と治療への応用2015
- Author(s)
  早川　芳弘
- Organizer
  がん分子標的学会
- Place of Presentation
  松山
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26430158
[Presentation] がん悪性化進展を促す炎症性免疫応答の維持機構におけるIL-17の重要2015
- Author(s)
  早川　芳弘、済木　育夫、入村　達郎
- Organizer
  日本がん転移学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26430158
[Presentation] がん治療標的としての宿主免疫応答2014
- Author(s)
  早川芳弘
- Organizer
  フォーラム富山創薬　第39回研究会
- Place of Presentation
  富山
- Year and Date
  2014-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-26430158
[Presentation] Cancer immuneescalation process and the role of inflammatory tumor microenvironment for promoting metastasis2013
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  Ninth AACR-JCR Joint Conference
- Place of Presentation
  Maui, HI, USA
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] IL-17-producing NK1.1+CD27- γδT cells promote tumor malignant progression by inducing inflammatory microenvironment2012
- Author(s)
  早川　芳弘、佐藤（松下）　まりも、田原　秀晃、済木　育夫、入村　達郎
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] ナチュラルキラー細胞の多様性とがん免疫応答における役割2012
- Author(s)
  早川　芳弘
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  広島
- Invited
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] 生物発光イメージングによるマウス4T1細胞の転移性微小環境における炎症性シグナル活性化の時空間的解析2012
- Author(s)
  高橋　恵生、入村　達郎、早川　芳弘
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] Cancer immune-escalation process and the role of inflammatory tumor microenvironment for promoting metastasis2012
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  The 14th International Biennial Congress of the Metastasis Research Society
- Place of Presentation
  Brisbane
- Invited
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] Cancer immuneescalation process and the role of inflammatory tumor microenvironment for promoting metastasis2012
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  The 14th International Biennial Congress of the Metastasis Research Society
- Place of Presentation
  Brisbane Convention & Exhibition Centre, Brisbane, Australia
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] がん免疫悪性化プロセスにおける炎症性サイトカインの役割2012
- Author(s)
  早川芳弘
- Organizer
  平成23年度個体レベルでのがん研究支援活動ワークショップ
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] IL-17-producing NK1.1+ CD27- γδT cells promote tumor malignant progression by inducing inflammatory microenvironment2012
- Author(s)
  Yoshihiro Hayakawa, Yoshitaka Kimura, Naoki Tsunekawa, Marimo Sato-Matsushita, Hideaki Tahara, Ikuo Saiki, Tatsuro Irimura
- Organizer
  第16回日本がん免疫学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] ナチュラルキラー細胞の多様性とがん免疫応答における役割2012
- Author(s)
  早川芳弘
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  オリエンタルホテル広島、広島
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] Evidences for cancer immune-escalation process and the role of inflammatory cytokines2011
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  The 16th Korea-Japan Cancer Research Workshop(招待講演)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] sialoglycoprotein receptor promotes cancer metastasis by activating EGFR-ERK pathway2011
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] Tatsuro Irimura Evidences for cancer immune-escalation process and the role of inflammatory cytokines.2011
- Author(s)
  早川芳弘
- Organizer
  Keystone Symposia "Cancer Control by Tumor Suppressors and Immune Effectors"
- Place of Presentation
  anta Fe Community Convention Center (Santa Fe, USA)
- Year and Date
  2011-02-14
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Cancer progression driven by microenvironment: role of cytokines revealed by novel in vivo model2011
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  The Joint International Meeting of the 76th Conference of Japanese Society of Interferon and Cytokine Research and the 19th International Symposium of Macrophage Molecular and Cell Biology 2011
- Place of Presentation
  大阪
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] がん免疫悪性化プロセスにおける炎症性サイトカインの役割2011
- Author(s)
  早川芳弘
- Organizer
  日本免疫学会総会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] Evidences for cancer immune-escalation process and the role of inflammatory cytokines2011
- Author(s)
  Yoshihiro Hayakawa, Tatsuro Irimura
- Organizer
  Keystone Symposia "Cancer Control by Tumor Suppressors and Immune Effectors"
- Place of Presentation
  Santa Fe Community Convention Center (Santa Fe, USA)
- Year and Date
  2011-02-14
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] 腫瘍微小環境へのNK細胞集積におけるIFN-γの重要性2011
- Author(s)
  早川芳弘
- Organizer
  「がん研究分野の特性等を踏まえた支援活動」平成23年度　がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] Evidences for cancer immune-escalation process andthe role of inflammatory cytokines2011
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  The 16th Korea-Japan Cancer Research Workshop
- Place of Presentation
  札幌
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] がん免疫悪性化プロセスにおける炎症性サイトカインの役割2011
- Author(s)
  早川芳弘
- Organizer
  日本がん転移学会総会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] Cancer progression driven by microenvironment: role of cytokines revealed by novel in vivo model2011
- Author(s)
  Yoshihiro Hayakawa
- Organizer
  The Joint International Meeting of the 76th Conference of Japanese Society of Interferon and Cytokine Research and the 19th International Symposium of Macrophage Molecular and Cell Biology 2011(招待講演)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23701073
[Presentation] 腫瘍微小環境へのNK細胞集積におけるIFN-γの重要性2010
- Author(s)
  早川芳弘、入村達郎
- Organizer
  第19回日本がん転移学会総会
- Place of Presentation
  金沢市文化ホール(石川)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] 腫瘍微小環境へのNK細胞集積におけるIFN-γの重要性2010
- Author(s)
  早川芳弘、佐藤まりも、田原秀晃、入村達郎
- Organizer
  第14回日本がん免疫学会
- Place of Presentation
  KKRホテル熊本(熊本)
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] 入村達郎腫瘍微小環境へのNK細胞集積におけるIFN-γの重要性2010
- Author(s)
  早川芳弘、佐藤まりも、田原秀晃
- Organizer
  第14回日本がん免疫学会
- Place of Presentation
  KKRホテル熊本(熊本)
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Requirement of endogenous IFN-gamma for effective recruitment of effector NK cells into tumor microenvironment.2010
- Author(s)
  早川芳弘、佐藤まりも、田原秀晃、入村達郎
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Phenotypic and functional diversity of mouse NK cells.2010
- Author(s)
  早川芳弘
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸国際会議場(兵庫)
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] マウスNK細胞サブッセットでの抑制性レセプターレパトア形成におけるMHC class Iの重要性と抗腫瘍免疫応答におけるその意義2009
- Author(s)
  早川芳弘
- Organizer
  第13回日本がん免疫学会総会
- Place of Presentation
  北九州国際会議場(北九州)
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] マウスNK細胞サブッセットでの抑制性レセプターレパトア形成におけるMHC class Iの重要性と抗腫瘍免疫応答におけるその意義2009
- Author(s)
  早川芳弘
- Organizer
  第18回日本がん転移学会学術集会・総会
- Place of Presentation
  旭川グランドホテル
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] マウスNK細胞サブッセットでの抑制性レセプターレパトア形成におけるMHC class Iの重要性と抗腫瘍免疫応答におけるその意義2009
- Author(s)
  早川芳弘
- Organizer
  第13回日本がん免疫学会総会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Distinct receptor repertoire formation in mouse NK cell subsets regulated by MHC class I expression and its implication in anti-tumor immune response.2009
- Author(s)
  早川芳弘
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Distinct receptor repertoire formation in mouse NK cell subsets regulated by MHC class I expression and its implication in anti-tumor immune response2009
- Author(s)
  早川芳弘
- Organizer
  39^<th> Annual Scientific Meeting, Australasian Society for Immunology
- Place of Presentation
  Cornard Jupiters (Gold Coast, Australia)
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] マウスNK細胞サブッセットでの抑制性レセプターレパトア形成におけるMHC class Iの重要性と抗腫瘍免疫応答におけるその意義2009
- Author(s)
  早川芳弘
- Organizer
  第18回日本がん転移学会学術集会・総会
- Place of Presentation
  旭川グランドホテル(旭川)
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Distinct receptor repertoire formation in mouse NK cell subsets regulated by MHC class I expression, and its implication in anti-tumor immune response2009
- Author(s)
  早川芳弘
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Distinct receptor repertoire formation in mouse NK cell subsets regulated by MHC class I expression and its implication in anti-tumor immune response2009
- Author(s)
  早川芳弘
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Distinct receptor repertoire formation in mouse NK cell subsets regulated by MHC class I expression, and its implication in anti-tumor immune response.2009
- Author(s)
  早川芳弘
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Distinct receptor repertoire formation in mouse NK cell subsets regulated by MHC class I expression and its implication in anti-tumor immune response.2009
- Author(s)
  早川芳弘
- Organizer
  39th Annual Scientific Meeting, Australasian Society for Immunology
- Place of Presentation
  Cornard Jupiters (Gold Coast, Australia)
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PROJECT-21890044
[Presentation] Vδ1 T細胞を起点とする自然炎症はがん悪性化を促進する
- Author(s)
  早川芳弘, 済木育夫, 入村達郎
- Organizer
  第23回日本がん転移学会
- Place of Presentation
  金沢
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26430158
[Presentation] Vδ1 T細胞を起点とする自然炎症はがん悪性化を促進する
- Author(s)
  早川芳弘, 木村好孝, 永井　直, 松下まりも, 田原秀晃, 善本隆之, 済木育夫, 入村達郎
- Organizer
  第18回日本がん免疫学会
- Place of Presentation
  松山
- Year and Date
  2014-07-31 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26430158

1. YOKOYAMA Satoru (90613498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. USUI Isao (50377272)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 薄田健史 (50880689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 山口哲志 (80398106)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TOGE Masayoshi (90456385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAIKI Ikuo (80133776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TSUNEYAMA Koichi (10293341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. Sakai Toshiyuki (20186993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Ohashi Wakana (50381596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 安田周祐 (10643398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 堀中真野 (80512037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 飯泉陽介 (20533178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 井村穣二 (80316554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 本間崇浩 (50436797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大平猛 (00275695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐々木宗一郎 (50583473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 林龍二 (60345585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 田井中一貴 (80506113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 泉尾直孝 (50722261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAGAWA takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. BANBURY Linda

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 竹田和由

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 岩倉洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. WIN NWET

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

hayakawa yoshihiro 早川 芳弘

HAYAKAWA Yoshihiro 早川 芳弘

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Elucidation of the exhaustion process of NK cells in tumorPrincipal Investigator

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老化線維芽細胞制御によるがん休眠細胞の封じ込めによる骨転移治療法の開発Principal Investigator

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Role of tissue-resident NK cells in tumor immune surveillance and their functional regulationPrincipal Investigator

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Exploration of tumor-promoting inflammatory immune responses and its application for cancer treatmentPrincipal Investigator

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がん悪性化に関わる炎症を制御する生理活性物質の探索Principal Investigator

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hayakawa yoshihiro 早川芳弘

HAYAKAWA Yoshihiro 早川芳弘

[Journal Article] 自然免疫制御を介したがん免疫療法の進展　2)NK細胞昨日の制御機構とがん免疫療法への応用2022