Sasaki Soichiro 佐々木宗一郎

… Alternative Names

Researcher Number	50583473
Other IDs
External Links
Affiliation (Current)	2021: 富山大学, 学術研究部薬学・和漢系, 助教
Affiliation (based on the past Project Information) *help	2015 – 2020: 金沢大学, がん進展制御研究所, 助教 2012 – 2013: 金沢大学, がん進展制御研究所, 博士研究員
Review Section/Research Field	Principal Investigator Tumor biology / Tumor biology / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator 大腸がん / 骨転移 / ケモカイン / 線維化 / HB-EGF / CCR5 / マラビロック / 線維芽細胞 / 乳がん / Bone metastasis / 腫瘍学 / 浸潤・転移 / がん

骨転移した乳がん細胞選択的に発現亢進するレセプター分子の病態生理学的役割の解析Principal Investigator
- Principal Investigator
  
  佐々木宗一郎
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Identification of novel target molecules involved in spontaneous bone metastasis of mouse breast cancer cell line.Principal Investigator
- Principal Investigator
  
  Sasaki Soichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
A possible novel anti-cancer treatment targeting CCL3-CCR5 interactionPrincipal Investigator
- Principal Investigator
  
  Sasaki Soichiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Elucidation of the adjustment mechanism with chemokines to fibrosis in tumor development and progression.Principal Investigator
- Principal Investigator
  
  SASAKI Soichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University

All 2019 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation Book

[Book] Tumor immunotherapy by utilizing a double-edged sword chemokines. Int Cancer Targeted Drug Deliverty; an Elusive Dream2013
- Author(s)
  Mukaida N., Sasaki S., Baba T.
- Publisher
  Springer Science + Business Media New York
- Data Source
  KAKENHI-PROJECT-24700973
[Book] Int. Cancer Targeted Drug Delivery; an Elusive Dream2013
- Author(s)
  Mukaida N, Sasaki S, Baba T
- Total Pages
  711
- Publisher
  Springer Verlag
- Data Source
  KAKENHI-PROJECT-24700973
[Book] A novel function of neutrophils via opioid peptides : maintenance of estrous cycle and regulation of pain, 生化学, (84(10))2012
- Author(s)
  小林芳郎、佐々木宗一郎
- Data Source
  KAKENHI-PROJECT-24700973
[Journal Article] Involvement of Prokineticin 2?expressing Neutrophil Infiltration in 5-Fluorouracil?induced Aggravation of Breast Cancer Metastasis to Lung2018
- Author(s)
  Sasaki Soichiro, Baba Tomohisa, Muranaka Hayato, Tanabe Yamato, Takahashi Chiaki, Matsugo Seiichi, Mukaida Naofumi.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: ahead of print Pages: 1515-1525
- DOI
  10.1158/1535-7163.mct-17-0845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07159, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17J06054, KAKENHI-PROJECT-16K08733, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K19681, KAKENHI-PROJECT-18K15237
[Journal Article] Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancer-associated fibroblast accumulation.2016
- Author(s)
  Tanabe Y, Sasaki S, Mukaida N, Baba T.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Pages: 48335-345
- DOI
  10.18632/oncotarget.10227
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18406, KAKENHI-PROJECT-16K08733
[Journal Article] Fibroblasts, an inconspicuous but essential player in colon cancer development and progression.2016
- Author(s)
  Mukaida N, Sasaki S.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 22 Pages: 5301-16
- DOI
  10.3748/wjg.v22.i23.5301
- NAID
  120005851382
- Open Access
- Data Source
  KAKENHI-PROJECT-15K18406
[Journal Article] Essential roles of the interaction between cancer cell-derived chemokine, CCL4, and intra-bone CCR5-expressing fibroblasts in breast cancer bone metastasis.2016
- Author(s)
  Sasaki S, Baba T, Nishimura T, Hayakawa Y, Hashimoto S, Gotoh N, Mukaida N.
- Journal Title
  
  Cancer Lett
  
  Volume: 378 Pages: 23-32
- DOI
  10.1016/j.canlet.2016.05.005
- NAID
  120005764205
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18406, KAKENHI-PROJECT-16K08733
[Journal Article] High-dose cyclophosphamide induces specific tumor immunity with conccomitant recruitment of LAMP1/CD107a-expressing CD4-positive T cells into tumor sites2015
- Author(s)
  Naito, T., Baba, T., Takeda, K., Sasaki, S., Nakamoto, Y. and Mukaida, N.
- Journal Title
  
  Cancer Lett
  
  Volume: 366 Pages: 93-99
- DOI
  10.1016/j.canlet.2015.06.009
- NAID
  120005663501
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14410, KAKENHI-PROJECT-26670379, KAKENHI-PROJECT-15K18406, KAKENHI-PROJECT-25460492, KAKENHI-PROJECT-25293171
[Journal Article] Gemcitabine-induced CXCL8 expression conteracts its action by inducing tumor neovascularization2015
- Author(s)
  Song Y, Baba T, Li YY, Furukawa K, Tanabe Y, Matsugo S, Sasaki S, Mukaida N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 458 Pages: 341-346
- DOI
  10.1016/j.bbrc.2015.01.112
- NAID
  120005593940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460492, KAKENHI-PROJECT-15K18406
[Journal Article] Ag and IL-2 immune complexes efficiently expand Ag-specific Treg cells that migrate in response to chemokines and reduce localized immune responses2014
- Author(s)
  Hamano R, Baba T, Sasaki S, Tomaru U, Ishizu A, Kawano M, Yamagishi M, Mukaida N
- Journal Title
  
  Ｅｕｒｏｐｅａｎ　Ｊｏｕｒｎａｌ　Ｏｆ　Ｉｍｍｕｎｏｌｏｇｙ
  
  Volume: 44 Pages: 1005-1015
- DOI
  10.1002/eji.201343434
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659171, KAKENHI-PROJECT-24700973, KAKENHI-PROJECT-25460489, KAKENHI-PROJECT-25460492, KAKENHI-PROJECT-25461181, KAKENHI-PROJECT-26860748
[Journal Article] Crucial Involvement of the CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice2014
- Author(s)
  Sasaki S, Baba T, Shinagawa K, Matsushima K, Mukaida N.
- Journal Title
  
  Int J Cancer
  
  Volume: In press
- DOI
  10.1002/ijc.28779
- NAID
  120005463351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700973, KAKENHI-PROJECT-25460492
[Journal Article] Effects of regular exercise on neutrophil functions, oxidative stress parameters and antibody responses against 4-hydroxy-2-nonenal adducts in middle aged humans.2013
- Author(s)
  Sasaki S, Matsuura T, Takahashi R, Iwasa T, Watanabe H, Shirai K, Nakamoto H, Goto S, Akita S, Kobayashi Y.
- Journal Title
  
  Exerc Immunol Rev.
  
  Volume: 19 Pages: 60-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700973
[Journal Article] Specific detection of intramitochondrial superoxide produced by either cell activation or apoptosis by employing a newly developed cell-permeative lucigenin derivative, 10,10'-dimethyl-9,9'-biacridinium b s(monomethyl terephthalate)2013
- Author(s)
  Sasaki S, Yamada S, Iwamura M, Kobayashi Y.
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 65 Pages: 1005-1011
- DOI
  10.1016/j.freeradbiomed.2013.08.175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700973
[Journal Article] A novel function of neutrophils via opioid peptides: maintenance of estrous cycle and regulation of pain2012
- Author(s)
  Kobayashi Yoshiro, Sasaki Soichiro
- Journal Title
  
  Seikagaku
  
  Volume: 84 Pages: 866-870
- NAID
  10031122396
- Data Source
  KAKENHI-PROJECT-24700973
[Presentation] 骨微小環境特異的にマウス乳がん細胞株で発現が亢進する転写因子を介した骨転移制御機構の解析2019
- Author(s)
  佐々木宗一郎、向田直史
- Organizer
  第28回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17K07159
[Presentation] 骨転移巣特異的に乳がん細胞で発現が亢進する転写因子の解析2019
- Author(s)
  佐々木宗一郎、向田直史
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07159
[Presentation] The role of transcription factors, Lmo2, Nfe2, Myb, in the regulation of bone metastasis in murine breast cancer model2019
- Author(s)
  Zhang D, Sasaki S, Baba T, and Mukaida N
- Organizer
  第77回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07159
[Presentation] Identification of novel target molecules involved in spontaneous bone metastasis of mouse breast cancer.2018
- Author(s)
  Sasaki S, Zhang D, Baba T,and Mukaida N
- Organizer
  第７７回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07159
[Presentation] ケモカインレセプターCCR5阻害剤による乳がん骨転移制御の可能性の検証2018
- Author(s)
  佐々木宗一郎、向田直史
- Organizer
  第２２回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07159
[Presentation] マウス乳がん細胞株による肺と骨への同時転移過程におけるMint3の役割の解明2018
- Author(s)
  佐々木宗一郎、坂本毅治, Di Zhang、馬場智久、向田直史
- Organizer
  第２７回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07159
[Presentation] Possibility of post-surgiccal adjuvant therapy with 5-fluorouracil to augment breast cancer metastasis to lungs2017
- Author(s)
  Sasaki S, Baba T, Mukaida N
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07159
[Presentation] 5-fluorouracil-induced neutrophilic chemokine expression in tumor cells is associated with accelerated lung metastasis of breast cancer2017
- Author(s)
  Sasaki S, Baba T, Mukaida N
- Organizer
  5th Annual Meeging of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07159
[Presentation] フルオロウラシル投与によるマウス乳がん肺転移の促進機構の解明2017
- Author(s)
  佐々木宗一郎、馬場智久、向田直史
- Organizer
  第26回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07159
[Presentation] 乳がんの骨転移過程におけるケモカインCCL4と線維芽細胞の関与2016
- Author(s)
  佐々木宗一郎、馬場智久、向田直史
- Organizer
  第25回日本がん転移学会学術集会・総会
- Place of Presentation
  米子コンベンションセンター、鳥取
- Year and Date
  2016-07-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K18406
[Presentation] Breast cancer cells derived inflammatory chemokine, CCL4, drive the bone metastasis in paracrine manner2016
- Author(s)
  Sasaki S, Baba T, and Mukaida N.
- Organizer
  第75回日本癌学会学術集会・総会
- Place of Presentation
  パシフィコ横浜、神奈川
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K18406
[Presentation] Blockade of a chemokine receptor, CCR5, reduces colon cancer growth by inhibiting cancer-associated fibroblast.2016
- Author(s)
  Tanabe Y, Sasaki S, Baba T, and Mukaida N.
- Organizer
  第75回日本癌学会学術集会・総会
- Place of Presentation
  パシフィコ横浜、神奈川
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K18406
[Presentation] 乳癌骨転移における腫瘍由来CCL4と骨内CCR5発現線維芽細胞の相互作用2016
- Author(s)
  佐々木宗一郎、馬場智久、向田直史
- Organizer
  第19回癌と骨病変研究会
- Place of Presentation
  千代田放送会館、東京
- Invited
- Data Source
  KAKENHI-PROJECT-15K18406
[Presentation] CCL4-CCR5 interacitons have pivotal roles in survival of a murine breast cancer cell line in osseous envirionment2015
- Author(s)
  Sasaki S, Baba T and Mukaida N
- Organizer
  12th World Congress on Inflammation
- Place of Presentation
  Seaport Hotel and World Trade Center (Boston)
- Year and Date
  2015-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18406
[Presentation] Tumor-derived CCL4 enhanced migration ability of mammary tumor cell lines to bone marrow in a paracrine manner2015
- Author(s)
  Sasaki S, Baba T and Mukaida N.
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K18406
[Presentation] 炎症性ケモカインCCL4は傍分泌型にマウス乳がん細胞株の骨転移を促進する2015
- Author(s)
  佐々木宗一郎、馬場智久、向田直史
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K18406
[Presentation] 慢性炎症大腸炎モデルではCCL3/CCR5を介して線維化、癌化が進行する2013
- Author(s)
  佐々木宗一郎、馬場智久、向田直史
- Organizer
  第72回日本免疫学会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-24700973
[Presentation] 慢性炎症大腸炎モデルではCCL3/CCR5を介して線維化、癌化が進行する2013
- Author(s)
  佐々木宗一郎、馬場智久、向田直史
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24700973
[Presentation] CCL3-CCR5 axis regulates progression of fibrosis occurring as a result of chronic colitis in mice2013
- Author(s)
  Soichiro Sasaki, Tomohisa Baba, Naofumi Mukaida
- Organizer
  3rd International Symposium on Carcinogenic Spiral and International Symposium on Tumor Biology in Kanazawa
- Place of Presentation
  金沢エクセルホテル東急(石川）
- Data Source
  KAKENHI-PROJECT-24700973
[Presentation] Crucial involvement of CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice2013
- Author(s)
  佐々木宗一郎、馬場智久、向田直史
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2013-12-11
- Data Source
  KAKENHI-PROJECT-24700973
[Presentation] Crucial involvement of CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice2013
- Author(s)
  Sasaki S, Baba T, and Mukaida N
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24700973
[Presentation] CCL3-CCR5 axis regulates progression of fibrosis/carcinogenesis occurring as a result of chronic colitis in mice2013
- Author(s)
  佐々木宗一郎、馬場智久、向田直史
- Organizer
  第8回研究所ネットワーク国際シンポジウム
- Place of Presentation
  京都
- Year and Date
  2013-06-27
- Data Source
  KAKENHI-PROJECT-24700973
[Presentation] Crucial contribution of CCL3-CCR5 axis, to murine chronic colitis-associated fibrosis/carcinogenesis2012
- Author(s)
  SASAKI Soichiro, BABA Tomohisa, MUKAIDA Naofumi
- Organizer
  第41回日本免疫学会総会
- Place of Presentation
  神戸国際会議場(兵庫）
- Data Source
  KAKENHI-PROJECT-24700973
[Presentation] Crucial involvement of the CCL3-CCR5 axis in mouse chronic colitis-associated carcinogenesis through regulating fibrosis2012
- Author(s)
  Soichiro Sasaki, Tomohisa Baba, Xiufeng Yang, Naofumi Mukaida
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道）
- Data Source
  KAKENHI-PROJECT-24700973

1. 向田直史 (30182067)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. BABA Tomohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
3. 石津明洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 外丸詩野

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 濱野良子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 竹田和由

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中本安成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 高橋智聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sasaki Soichiro 佐々木 宗一郎

SASAKI Soichiro 佐々木 宗一郎

Research Projects

Research Products

Co-Researchers

骨転移した乳がん細胞選択的に発現亢進するレセプター分子の病態生理学的役割の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel target molecules involved in spontaneous bone metastasis of mouse breast cancer cell line.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A possible novel anti-cancer treatment targeting CCL3-CCR5 interactionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the adjustment mechanism with chemokines to fibrosis in tumor development and progression.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Tumor immunotherapy by utilizing a double-edged sword chemokines. Int Cancer Targeted Drug Deliverty; an Elusive Dream2013

Author(s)

Publisher

Data Source

[Book] Int. Cancer Targeted Drug Delivery; an Elusive Dream2013

Author(s)

Total Pages

Publisher

Data Source

[Book] A novel function of neutrophils via opioid peptides : maintenance of estrous cycle and regulation of pain, 生化学, (84(10))2012

Author(s)

Data Source

[Journal Article] Involvement of Prokineticin 2?expressing Neutrophil Infiltration in 5-Fluorouracil?induced Aggravation of Breast Cancer Metastasis to Lung2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancer-associated fibroblast accumulation.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibroblasts, an inconspicuous but essential player in colon cancer development and progression.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Essential roles of the interaction between cancer cell-derived chemokine, CCL4, and intra-bone CCR5-expressing fibroblasts in breast cancer bone metastasis.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] High-dose cyclophosphamide induces specific tumor immunity with conccomitant recruitment of LAMP1/CD107a-expressing CD4-positive T cells into tumor sites2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Gemcitabine-induced CXCL8 expression conteracts its action by inducing tumor neovascularization2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Ag and IL-2 immune complexes efficiently expand Ag-specific Treg cells that migrate in response to chemokines and reduce localized immune responses2014

Author(s)

Journal Title

DOI

Data Source

Sasaki Soichiro 佐々木宗一郎

SASAKI Soichiro 佐々木宗一郎