SHIRO Watanabe 渡辺志朗

Researcher Number	00222406
Other IDs
Affiliation *help	2011 – 2018 : 富山大学, 和漢医薬学総合研究所, 准教授 1999 – 2001 : 富山医科薬科大学, 和漢薬研究所, 助教授 1997 – 1998 : 名古屋市立大学, 薬学部, 講師 1993 : 名古屋市立大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / General internal medicine (including Psychosomatic medicine) / General internal medicine(including psychosomatic medicine) / Basic Section 52010:General internal medicine-related Except Principal Investigator 矯正・小児・社会系歯学 / Eating habits / Biological pharmacy
Keywords	Principal Investigator 胆汁酸 / エイコサペンタエン酸 / マクロファージ / ドコサヘキサエン酸 / HMG-CoA還元酵素 / 硫酸抱合化 / インターロイキンlB / トリグリセリド / 寿命 / マウス … More Except Principal Investigator α-リノレン酸 / 炎症 / acetylcholine / モノアミン / eicosapentaenoic acid / 植物油 / fatty acid composition / なたね油 / linoleic aicd / エイコサペンタエン酸 / 二重盲検法 / アセチルコリン / 大豆油 / aphthous stomatitis / 脳虚血モデルマウス / AMPA受容体 / シソ油 / monoamine / intervention study / 神経成長因子 / 摂食障害 / alpha-linolenic acid / docosahexaenoic acid / 口内炎 / 海馬神経細胞死 / nerve growth factor / α‐リノレン酸 / 学習能 / perilla oil / ドコサヘキサエン酸 / learning ability / soybean oil / 脂肪酸構成 / 介入試験 / リノール酸 / しそ油 / rapeseed oil Less

Experimental assessment of preventive effects of kampo medicines against metabolic syndromes through the modification of intestinal bile acid metabolismPrincipal InvestigatorOngoing
- Principal Investigator
  
  渡辺志朗
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  University of Toyama
脳虚血モデルマウスにみられる摂食障害に対するn-3系脂肪酸の予防効果の評価Ongoing
- Principal Investigator
  
  道志勝
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Teikyo University
Role of pregnane X receptor in the preventive effect of Boiogito against experimentally induced cholestatic liver injuryPrincipal Investigator
- Principal Investigator
  
  Watanabe Shiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Toyama
Detection of novel actions of kampo medicines for lipid metabolism by lipidomic analysisPrincipal Investigator
- Principal Investigator
  
  SHIRO Watanabe
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
Prevention of aphtous stomatitis with α-linolenic acid -a double-blind study-
- Principal Investigator
  
  HAMAZAKI Tomohito
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Toyama Medical and Pharmaceutical University
食餌n-3系不飽和脂肪酸がII型糖尿病に及ぼす影響とその機構の解析Principal Investigator
- Principal Investigator
  
  渡辺志朗
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toyama Medical and Pharmaceutical University
食餌性n-3系不飽和脂肪酸の生理・病態に及ぼす影響の基礎的研究Principal Investigator
- Principal Investigator
  
  渡辺志朗
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
Mechanisms by which dietary oils affect behavioral patterns of rats
- Principal Investigator
  
  OKUYAMA Harumi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
食餌必須脂肪酸バランスによる腫瘍壊死因子(TNF)産生制御の機構に関する研究Principal Investigator
- Principal Investigator
  
  渡辺志朗
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University

All 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Ursodeoxycholic acid suppresses lipogenesis in mouse liver: possible role of the decrease in β-muricholic acid, a farnesoid X receptor antagonist.2017
- Author(s)
  Fujita K., Iguchi Y., Une M., Watanabe S.
- Journal Title
  
  Lipids
  
  Volume : 52 Pages : 335-344
- DOI
  10.1007/s11745-017-4242-5
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460903
[Journal Article] Changes in liver lipidomics associated with sodium cholate-induced liver injury and its prevention by Boiogito, a Japanese herbal medicine, in mice.2016
- Author(s)
  Watanabe S, Fujita K, Tsuneyama K, Nose M.
- Journal Title
  
  Trad Kampo Med.
  
  Volume : 3 Pages : 9-19
- DOI
  10.1002/tkm2.1032
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460903
[Journal Article] A novel method for determining peroxisomal fatty acid β-oxidation.2016
- Author(s)
  Masashi Morita, Shun Matsumoto, Airi Okazaki, Kaito Tomita, Shiro Watanabe, Kosuke Kawaguchi, Daishiro Minato, Yuji Matsuya, Nobuyuki Shimozawa, Tsuneo Imanaka.
- Journal Title
  
  J Inherit. Metab. Dis.
  
  Volume : 39 Pages : 725-731
- DOI
  10.1007/s10545-016-9952-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04875, KAKENHI-PROJECT-26460063, KAKENHI-PROJECT-26460903, KAKENHI-PROJECT-15K15389
[Journal Article] Dipasperoside B, a new trisiridoid glucoside from Dipsacus asper.2016
- Author(s)
  Li F., Tanaka K., Watanabe S., Tezuka Y.
- Journal Title
  
  Nat. Prod. Commun.
  
  Volume : 11 Pages : 891-894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460903
[Journal Article] Chemical profiling with HPLC-FTMS of exogenous and endogenous chemicals susceptible to the administration of chotosan in an animal model of type 2 diabetes-induced dementia.2015
- Author(s)
  Niu Y, Li F, Inada C, Tanaka K, Watanabe S, Fujiwara H, Sasaki-Hamada S, Oka J, Matsumoto K.
- Journal Title
  
  J Pharm Biomed Anal.
  
  Volume : 104 Pages : 21-30
- DOI
  10.1016/j.jpba.2014.11.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460903
[Journal Article] Brain microsomal fatty acid elongation is increased in abcd1-deficient mouse during active myelination phase2015
- Author(s)
  Morita M, Kawamichi M, Shimura Y, Kawaguchi K, Watanabe S, Imanaka T.
- Journal Title
  
  Metab Brain Dis
  
  Volume : 30 Pages : 1359-1367
- DOI
  10.1007/s11011-015-9701-1
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460063, KAKENHI-PROJECT-26460903
[Journal Article] Dietary hyodeoxycholic acid exerts hypolipidemic effects by reducing farnesoid X receptor antagonist bile acids in mouse enterohepatic tissues.2014
- Author(s)
  Watanabe S, Fujita K.
- Journal Title
  
  Lipids
  
  Volume : 49 Pages : 963-973
- DOI
  10.1007/s11745-014-3947-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460903
[Journal Article] Role of transient receptor potential vanilloid 4 activation in indomethacin-induced intestinal damage2014
- Author(s)
  Yamawaki H, Mihara H, Suzuki N, Nishizono H, Uchida K, Watanabe S, Tominaga M, Sugiyama T.
- Journal Title
  
  Am. J. Physiol. Gastrointest. Liver Physiol.
  
  Volume : 307
- DOI
  10.1152/ajpgi.00105.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460903, KAKENHI-PROJECT-26870214, KAKENHI-PROJECT-23590873
[Journal Article] Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet2013
- Author(s)
  Watanabe S., Tsuneyama K.
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume : 38 Pages : 379-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Journal Article] Pig bile reduces hepatic triglyceride content in mice2013
- Author(s)
  Watanabe S., Fujita K.
- Journal Title
  
  J. Trad. Med.
  
  Volume : 30 Pages : 190-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Journal Article] Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet.2013
- Author(s)
  Watanabe S., Tsuneyama K
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume : 38 Pages : 379-390
- DOI
  10.2131/jts.38.379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Journal Article] Pig bile reduces hepatic triglyceride content in mice.2013
- Author(s)
  Watanabe S., Fujita K
- Journal Title
  
  J. Trad. Med.
  
  Volume : 30 Pages : 190-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Journal Article] Dipasperoside A, a Novel Pyridine Alkaloid-Coupled Iridoid Glucoside from the Roots of Dipsacus asper2013
- Author(s)
  Li F., Tanaka K., Watanabe S., Tezuka Y., Saiki I.
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume : 61 Pages : 1318-1322
- DOI
  10.1248/cpb.c13-00546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Journal Article] Evaluation of the quality of Chinese and Vietnamese cassia using LC-MS and multivariate analysis2013
- Author(s)
  Tanaka K., Li F., Tezuka Y., Watanabe S., Kawahara N., Kida H.
- Journal Title
  
  Nat. Prod. Commun.
  
  Volume : 8 Pages : 75-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Journal Article] Cattle bile but not bear bile or pig bile induces lipid profile changes and fatty liver injury in mice: mediation by cholic acid.2012
- Author(s)
  Watanabe S., Tsuneyama K.
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume : 37 Pages : 105-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Journal Article] Cattle bile but not bear bile or pig bile induces lipid profile changes and fatty liver injury in mice : mediation by cholic acid2012
- Author(s)
  Watanabe S., Tsuneyama K.
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume : 37 Pages : 105-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Journal Article] A new methodology for simultaneous quantification of total-Aβ, Aβx-38, Aβx-40, and Aβx-42 by column-switching LC/MS/MS.2012
- Author(s)
  Watanabe K, Ishikawa C, Kuwahara H, Sato K, Komuro S, Nakagawa T, Nomura N, Watanabe S, Yabuki M.
- Journal Title
  
  Anal. Bioanal. Chem.
  
  Volume : 402 Pages : 2033-2042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Journal Article] Cattle bile aggravates diclofenac sodium-induced small intestinal injury in mice2011
- Author(s)
  Ishikawa H., Watanabe S.
- Journal Title
  
  Evid. Based. Complement. Alternat. Med.
- DOI
  10.1155/2011/315858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] α‐リノレン酸の給餌が脳リン脂質中エイコサノイド前駆体脂肪酸含量に及ぼす影響2017
- Author(s)
  道志勝、渡辺志朗、藤田恭輔、富岡直子、細山田真、赤江豊
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K00848
[Presentation] ヒオデオキシコール酸の投与はTSODマウスの肝臓における炎症・線維化を促進する．2017
- Author(s)
  渡辺志朗、藤田恭輔、西田建志、井村譲二、常山幸一
- Organizer
  TSODマウス研究会情報交換会
- Place of Presentation
  つくば市
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] 防己黄耆湯のリトコール酸誘導胆汁うっ滞モデルマウスに対する改善効果.2017
- Author(s)
  藤田恭輔, 渡辺志朗. 2017, 3, 24-27, 仙台
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] 脳虚血モデルマウスにみられる摂食障害に対するω３系脂肪酸の軽減効果2016
- Author(s)
  道志勝、渡辺志朗、藤田恭輔、富岡直子、細山田真
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K00848
[Presentation] 脳虚血モデルマウスにみられる摂食障害に対するω３系脂肪酸の軽減効果2016
- Author(s)
  道志勝、渡辺志朗、藤田恭輔、富岡直子、細山田真、赤江豊
- Organizer
  日本脂質栄養学会第２５回大会
- Place of Presentation
  秋田市にぎわい交流館AU（秋田市）
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-15K00848
[Presentation] リトコール酸誘導胆汁うっ滞モデルマウスにおける肝傷害ならびに胆汁酸蓄積に対する防己黄耆湯の軽減効果．2016
- Author(s)
  渡辺志朗、辻哲也、藤田恭輔
- Organizer
  第33回和漢医薬学会学術大会
- Place of Presentation
  東京
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] ヒオデオキシコール酸のデキストラン硫酸ナトリウム誘発大腸炎に対する改善効果.2016
- Author(s)
  藤田恭輔, 杉山和恵, 西川将司, 上田浩, 渡辺志朗.
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] Ursodeoxycholic acid suppresses lipogenesis and reduces lipid contents in mouse liver possibly by reducing β-muricholic acid, a farnesoid X receptor antagonist.2016
- Author(s)
  Shiro Watanabe, Kyosuke Fujita
- Organizer
  The first international symposium on Toyama-Asia-Africa Pharmaceutical network
- Place of Presentation
  富山
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] 胆汁酸負荷による肝障害に対する防已黄耆湯の軽減効果2015
- Author(s)
  渡辺志朗、藤田恭輔
- Organizer
  第14回日本臨床中医薬学会学術大会
- Place of Presentation
  富山市
- Year and Date
  2015-09-29
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] 大柴胡湯の抗肥満作用に関する研究2015
- Author(s)
  小西明伸、荒　哲也，山崎寛生、渡辺志朗、藤田恭輔
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋市
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] ヒオデオキシコール酸はTSODマウスにおける肝炎症反応を促進する2015
- Author(s)
  藤田恭輔、常山幸一、渡辺志朗
- Organizer
  第38回胆汁酸研究会
- Place of Presentation
  横浜市
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] TSODマウスの肝炎に及ぼすヒオデオキシコール酸の効果2015
- Author(s)
  藤田恭輔、常山幸一、渡辺志朗
- Organizer
  日本薬学会北陸支部第127回例会
- Place of Presentation
  富山市
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] 豚胆主要成分ヒオデオキシコール酸が肥満モデルマウスに与える影響2015
- Author(s)
  藤田恭輔、常山幸一、辻　哲也、渡辺志朗
- Organizer
  第32回和漢医薬学会学術大会
- Place of Presentation
  富山市
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] マウスにおけるヒオデオキシコール酸とウルソデオキシコール酸の脂質低下作用の比較2014
- Author(s)
  渡辺志朗，藤田恭輔
- Organizer
  第36回胆汁酸研究会
- Place of Presentation
  東京
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] ケイヒのLC-MSによる網羅的成分分析と産地特有のマーカー化合物の同定2013
- Author(s)
  田中謙、李峰、渡辺志朗、川原信夫
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 加味四物湯のサルコペニア(筋肉減少症)改善作用の検討(2)2013
- Author(s)
  田邊宏樹、水野弘樹、井上未央里、森智一、中島健一、渡辺志朗、林忠紘、中島賢治、和田篤敬、井上誠
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] Exogenous/endogenous substances detected in the plasma and brain after chitosan treatment in mice.2013
- Author(s)
  牛一民、稲田千香子、趙キ、李峰、渡辺志朗、岡淳一郎、松本欣三
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 加味四物湯のサルコペニア（筋肉減少症）改善作用の検討（２）2013
- Author(s)
  田邊宏樹、水野弘樹、井上未央里、森智一、中島健一、渡辺志朗、林忠紘、中島賢治、和田篤敬、井上誠
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] Exogenous/endogenous substances detected in the plasma and brain after chitosan treatment in mice2013
- Author(s)
  牛一民、稲田千香子、趙キ、李峰、渡辺志朗、岡淳一郎、松本欣三
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 防已黄耆湯の胆汁酸誘発性肝障害抑制作用2013
- Author(s)
  藤田恭輔、田中謙、能勢充彦、渡辺志朗
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] ケイヒのLC-MSによる網羅的成分分析と産地特有のマーカー化合物の同定2013
- Author(s)
  田中謙、李　峰、渡辺志朗、川原信夫
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] A new methodology for simultaneous quantification of total-Aβ, Aβx-38, Aβx-40, and Aβx-42 by column-switching-LC/MS/MS2012
- Author(s)
  渡辺健一, 石川千裕, 桑原弘, 佐藤公彦, 小室勢津子, 中川徹也, 野村成章, 矢吹昌司, 渡辺志朗
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 豚胆の脂質低下作用2012
- Author(s)
  渡辺志朗、李峰、米山惇志、湖間戸俊輔
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] コール酸/高脂肪添加食によって誘導される脂肪性肝炎様症状に及ぼすエイコサペンタエン酸の影響2012
- Author(s)
  渡辺志朗
- Organizer
  日本脂質栄養学会第21回大会
- Place of Presentation
  麻布
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 胆汁酸添加高脂肪食によって誘導される脂肪性肝炎様症状に及ぼすエイコサペンタエン酸の影響2012
- Author(s)
  渡辺志朗
- Organizer
  胆汁酸研究会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] Eicosapentenoic acid supplementation attenuates hepatic accumulation of cholesterol esters but aggravates liver injury in mice fed a fatand sodium cholate-supplemented diet in mice2012
- Author(s)
  Shiro Watanabe
- Organizer
  The 1st International Conferecence on Pharma and Food
- Place of Presentation
  Shizuoka
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] Phytochemical study on the root of Dipsacus asper, a Kampo medicine.2012
- Author(s)
  李峰、渡辺志朗、手塚康弘、田中謙
- Organizer
  日本生薬学会第59回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] コール酸/高脂肪添加食によって誘導される脂肪性肝炎様症状に及ぼすエイコサペンタエン酸の影響2012
- Author(s)
  渡辺志朗
- Organizer
  日本脂質栄養学会第21回大会
- Place of Presentation
  麻布
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] Phytochemical study on the root of Dipsacus asper, a Kampo medicine2012
- Author(s)
  李峰、渡辺志朗、手塚康弘、田中謙
- Organizer
  日本生薬学会第59回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] Eicosapentenoic acid supplementation attenuates hepatic accumulation of cholesterol esters but aggravates liver injury in mice fed a fat- and sodium cholate-supplemented diet in mice2012
- Author(s)
  Shiro Watanabe
- Organizer
  The 1st International Conference on Pharma and Food
- Place of Presentation
  Shizuoka
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 胆汁酸添加高脂肪食によって誘導される脂肪性肝炎様症状に及ぼすエイコサペンタエン酸の影響2012
- Author(s)
  渡辺志朗
- Organizer
  胆汁酸研究会
- Place of Presentation
  名古屋
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 豚胆の脂質低下作用2012
- Author(s)
  渡辺志朗、李峰、米山惇志、湖間戸俊輔
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Year and Date
  2012-09-12
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] A new methodology for simultaneous quantification of total-Aβ, Aβx-38, Aβx-40, and Aβx-42 by column-switching-LC/MS/MS2012
- Author(s)
  渡辺健一,石川千裕,桑原弘,佐藤公彦,小室勢津子,中川徹也,野村成章,矢吹昌司,渡辺志朗
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 牛胆によって誘導される脂質代謝変化と脂肪性肝炎様症状における胆汁酸の役割,2011
- Author(s)
  渡辺志朗
- Organizer
  第33回胆汁酸研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 牛胆によって誘導される脂質代謝変化と脂肪性肝炎様症状における胆汁酸の役割2011
- Author(s)
  渡辺志朗
- Organizer
  第33回胆汁酸研究会
- Place of Presentation
  大阪
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 牛胆の投与によって誘導される脂肪性肝炎様症状に伴う脂質代謝変化の解析2011
- Author(s)
  渡辺　志朗
- Organizer
  第12回Pharmaco-hematology Symposium
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] トランス脂肪酸は脂肪細胞のインスリン応答性を低下させる2011
- Author(s)
  大嶋利之、澤田啓介、根橋佳奈、大蔵直樹、渡辺志朗、厚味厳一
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] エイコサペンタエン酸がコール酸添加高脂肪食により誘導される脂肪性肝炎様症状に及ぼす影響2011
- Author(s)
  渡辺志朗、吉田康彦、湖間戸俊輔、浜田雄大、常山幸一
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] トランス脂肪酸は脂肪細胞のインスリン応答性を低下させる2011
- Author(s)
  大嶋利之、澤田啓介、根橋佳奈、大蔵直樹、渡辺志朗、厚味厳一
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 牛胆の投与によって誘導される脂肪性肝炎様症状に伴う脂質代謝変化の解析2011
- Author(s)
  渡辺志朗
- Organizer
  第12回Pharmaco-hematology Symposium
- Place of Presentation
  富山
- Year and Date
  2011-06-20
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] エイコサペンタエン酸がコール酸添加高脂肪食により誘導される脂肪性肝炎様症状に及ぼす影響2011
- Author(s)
  渡辺志朗、吉田康彦、湖間戸俊輔、浜田雄大、常山幸一
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 牛胆は一価不飽和脂肪酸含有コレステロールエステルの優位な蓄積を伴う脂肪肝を誘導する2011
- Author(s)
  渡辺志朗,常山幸一
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] 脂肪細胞でのトランス脂肪酸によるインスリン抵抗性に関する解析2011
- Author(s)
  澤田啓介,根橋佳奈,大藏直樹,渡辺志朗,厚味厳一
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] Chemical profiling of endogenous and exogenous markers of chitosan in an animal model of diabetes
- Author(s)
  Niu Yimin, Li Feng, Hironori Fujiwara, Ken Tanaka, Shiro Watanabe, Sachie Sasak-Hamada, Jun-Ichiro Oka, Kinzo Matsumoto
- Organizer
  第31回和漢医薬学会学術大会
- Place of Presentation
  千葉
- Year and Date
  2014-08-30 – 2014-08-31
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] 脂肪酸構成の網羅的分析によるコール酸誘発性肝障害とその防已黄耆湯による軽減の機構解析
- Author(s)
  渡辺志朗，藤田恭輔
- Organizer
  第31回和漢医薬学会学術大会
- Place of Presentation
  千葉
- Year and Date
  2014-08-30 – 2014-08-31
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] 大柴胡湯の抗肥満作用の検討
- Author(s)
  林忠紘、荒哲也、和田篤敬、藤田恭輔、渡辺志朗
- Organizer
  日本生薬学会第61年会
- Place of Presentation
  福岡
- Year and Date
  2014-09-13 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] ヒオデオキシコール酸およびウルソデオキシコール酸の肝臓中トリグリセリド含量低下作用
- Author(s)
  藤田恭輔、松川征也、井上俊、渡辺志朗
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460903
[Presentation] 豚胆の脂質低下作用における主要構成胆汁酸の役割
- Author(s)
  渡辺志朗、藤田恭輔
- Organizer
  第35回胆汁酸研究会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590873
[Presentation] コール酸誘導性肝傷害および肝臓脂質代謝変動に対する防己黄耆湯の効果
- Author(s)
  藤田恭輔、田中謙、能勢充彦、渡辺志朗
- Organizer
  第35回胆汁酸研究会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590873

1. TSUNEYAMA Koichi (10293341)

# of Collaborated Projects : 1results

# of Collaborated Products : 7results
2. OKUYAMA Harumi (90080176)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
3. IKEMOTO Atsushi (60295615)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. HAMAZAKI Tomohito (70167592)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. 藤田恭輔 (70707538)

# of Collaborated Projects : 1results

# of Collaborated Products : 17results
6. 道志勝 (30392385)

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
7. 三原弘

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
8. 今中常雄

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
9. 川口甲介

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
10. 下澤伸行

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

SHIRO Watanabe 渡辺 志朗

Research Projects

Research Products

Co-Researchers

Experimental assessment of preventive effects of kampo medicines against metabolic syndromes through the modification of intestinal bile acid metabolismPrincipal InvestigatorOngoing

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脳虚血モデルマウスにみられる摂食障害に対するn-3系脂肪酸の予防効果の評価Ongoing

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Role of pregnane X receptor in the preventive effect of Boiogito against experimentally induced cholestatic liver injuryPrincipal Investigator

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Detection of novel actions of kampo medicines for lipid metabolism by lipidomic analysisPrincipal Investigator

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Prevention of aphtous stomatitis with α-linolenic acid -a double-blind study-

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食餌n-3系不飽和脂肪酸がII型糖尿病に及ぼす影響とその機構の解析Principal Investigator

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食餌性n-3系不飽和脂肪酸の生理・病態に及ぼす影響の基礎的研究Principal Investigator

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Mechanisms by which dietary oils affect behavioral patterns of rats

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食餌必須脂肪酸バランスによる腫瘍壊死因子(TNF)産生制御の機構に関する研究Principal Investigator

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[Journal Article] Ursodeoxycholic acid suppresses lipogenesis in mouse liver: possible role of the decrease in β-muricholic acid, a farnesoid X receptor antagonist.2017

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[Journal Article] Changes in liver lipidomics associated with sodium cholate-induced liver injury and its prevention by Boiogito, a Japanese herbal medicine, in mice.2016

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[Journal Article] A novel method for determining peroxisomal fatty acid β-oxidation.2016

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[Journal Article] Dipasperoside B, a new trisiridoid glucoside from Dipsacus asper.2016

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[Journal Article] Chemical profiling with HPLC-FTMS of exogenous and endogenous chemicals susceptible to the administration of chotosan in an animal model of type 2 diabetes-induced dementia.2015

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SHIRO Watanabe 渡辺志朗