GOTO Masanori 後藤正憲

… Alternative Names

後藤正憲ゴトウマサノリ

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Researcher Number	00432203
Other IDs
Affiliation (Current)	2025: 旭川医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2022: 旭川医科大学, 医学部, 助教 2012: 浜松医科大学, 医学部, 特別研究員 2012: 浜松医科大学, 医学部, 研究員 2010 – 2011: 浜松医科大学, 医学部, 特任研究員
Review Section/Research Field	Principal Investigator Experimental pathology Except Principal Investigator Basic Section 49030:Experimental pathology-related
Keywords	Principal Investigator 胃がん / 塩基除去修復 / TDG / 塩基除去修復酵素 / 過酸化脂質 / 活性酸素種 / 大腸がん / 塩基除去修復遺伝子 / エテノアダクト / MUTYH / 8-ヒドロキシグアニン … More Except Principal Investigator … More 胆管癌 / 原発性肝癌 / 分化転換」 / 脱分化 / 分化転換 / 混合型肝癌 / 胆管細胞癌 / 肝細胞癌 / 肝腫瘍 Less

Mechanisms determining the wide spectrum of hepatocytic tumors
- Principal Investigator
  
  Nishikawa Yuji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Asahikawa Medical College
The investigation of the association between variants of the base excision repair(BER) enzymes and carcinogenesis, and the repair activities of BER enzymes against etheno-DNA adductsPrincipal Investigator
- Principal Investigator
  
  GOTO Masanori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Hamamatsu University School of Medicine

All 2023 2022 2021 2020 2019 2012 2011 2010

All Journal Article Presentation

[Journal Article] High levels of Myc expression are required for the robust proliferation of hepatocytes, but not for the sustained weak proliferation2023
- Author(s)
  Goto Masanori、Ooshio Takako、Yamamoto Masahiro、Tanaka Hiroki、Fujii Yumiko、Meng Lingtong、Kamikokura Yuki、Okada Yoko、Nishikawa Yuji
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1869 Issue: 4 Pages: 166644-166644
- DOI
  10.1016/j.bbadis.2023.166644
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03448, KAKENHI-PROJECT-20K07558, KAKENHI-PROJECT-23K06667, KAKENHI-PROJECT-20K07443
[Journal Article] Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway2022
- Author(s)
  Kawabata Hidemasa、Ono Yusuke、Tamamura Nobue、Oyama Kyohei、Ueda Jun、Sato Hiroki、Takahashi Kenji、Taniue Kenzui、Okada Tetsuhiro、Fujibayashi Syugo、Hayashi Akihiro、ほか
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 57 Issue: 3 Pages: 208-220
- DOI
  10.1007/s00535-021-01846-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16947, KAKENHI-PUBLICLY-20H04896, KAKENHI-PROJECT-19K07261, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K07954, KAKENHI-PROJECT-20K17009, KAKENHI-PROJECT-21KK0283, KAKENHI-PROJECT-22KK0125, KAKENHI-PROJECT-19H03448, KAKENHI-PROJECT-20H03655, KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-20K09070, KAKENHI-PROJECT-19K17480, KAKENHI-PROJECT-19K06452, KAKENHI-PROJECT-21H02758
[Journal Article] Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice2021
- Author(s)
  Meng Lingtong、Goto Masanori、Tanaka Hiroki、Kamikokura Yuki、Fujii Yumiko、Okada Yoko、Furukawa Hiroyuki、Nishikawa Yuji
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 191 Issue: 9 Pages: 1580-1591
- DOI
  10.1016/j.ajpath.2021.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03448
[Journal Article] Generation of combined hepatocellular‐cholangiocarcinoma through transdifferentiation and dedifferentiation in p53‐knockout mice2021
- Author(s)
  Liu Yang、Xin Bing、Yamamoto Masahiro、Goto Masanori、Ooshio Takako、Kamikokura Yuki、Tanaka Hiroki、Meng Lingtong、Okada Yoko、Mizukami Yusuke、Nishikawa Yuji
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 8 Pages: 3111-3124
- DOI
  10.1111/cas.14996
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03448, KAKENHI-PROJECT-20K07558
[Journal Article] Hepatocyte MKK7 Contributes to Restoration of the Liver Parenchyma Following Injury2020
- Author(s)
  Ooshio Takako、Yamamoto Masahiro、Fujii Kiyonaga、Xin Bing、Watanabe Kenji、Goto Masanori、Okada Yoko、Suzuki Akira、Penninger Josef M.、Nishina Hiroshi、Nishikawa Yuji
- Journal Title
  
  Hepatology
  
  Volume: online Issue: 6 Pages: 31565-31565
- DOI
  10.1002/hep.31565
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20661, KAKENHI-PROJECT-17H01400, KAKENHI-PROJECT-19H03448, KAKENHI-PUBLICLY-20H04905, KAKENHI-PROJECT-21H04806, KAKENHI-PROJECT-20K07558
[Journal Article] Low bone mineral density due to secondary hyperparathyroidism in theGlatmTg(CAG‐A4GALT)mouse model of Fabry disease2020
- Author(s)
  Maruyama Hiroki、Taguchi Atsumi、Mikame Mariko、Lu Hongmei、Tada Norihiro、Ishijima Muneaki、Kaneko Haruka、Kawai Mariko、Goto Sawako、Saito Akihiko、Ohashi Riuko、Nishikawa Yuji、Ishii Satoshi
- Journal Title
  
  FASEB BioAdvances
  
  Volume: 2 Issue: 6 Pages: 365-381
- DOI
  10.1096/fba.2019-00080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09082, KAKENHI-PROJECT-19H03448
[Journal Article] Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations2019
- Author(s)
  Watanabe K, Yamamoto M, Xin B, Ooshio T, Goto M, Fujii K, Liu Y, Okada Y, Furukawa H, Nishikawa Y.
- Journal Title
  
  Hepatology Communications
  
  Volume: 3 Issue: 5 Pages: 697-715
- DOI
  10.1002/hep4.1327
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17573, KAKENHI-PROJECT-19H03448
[Journal Article] Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis2012
- Author(s)
  Shinmura K, Goto M, Tao H, Matsuura S, Matsuda T, Sugimura H
- Journal Title
  
  World J Gastroenterol
  
  Volume: 18 Issue: 47 Pages: 6935-6942
- DOI
  10.3748/wjg.v18.i47.6935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590356, KAKENHI-PROJECT-22790378, KAKENHI-PROJECT-24659161
[Journal Article] Lipid peroxidation-induced DNA adducts in human gastric mucosa2012
- Author(s)
  Matsuda T, Tao H, Goto M, Yamada H, Suzuki M, Wu Y, Xiao N, He Q, Guo W, Cai Z, Kurabe N, Ishino K, Matsushima Y, Shinmura K, Konno H, Maekawa M, Wang Y, Sugimura H
- Journal Title
  
  Carcinogenesis
  
  Volume: 34 Issue: 1 Pages: 121-127
- DOI
  10.1093/carcin/bgs327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790378, KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-24659161
[Journal Article] Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer2011
- Author(s)
  Shinmura, et.Al
- Journal Title
  
  The Journal of Pathology
  
  Volume: 225 Issue: 3 Pages: 414-423
- DOI
  10.1002/path.2953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790383, KAKENHI-PROJECT-22590356, KAKENHI-PROJECT-22790378, KAKENHI-PROJECT-23221006
[Journal Article] Genetic susceptibility to lung cancer2011
- Author(s)
  H.Sugimura, H.Tao, M.Suzuki, H.Mori, M.Tsuboi, S.Matsuura, M.Goto, K.Shimnura, T.Ozawa, F.Tanioka, N.Sato, Yoshitaka Matsushima, S.Kageyama, K.Funai, P.-H.Chou, T.Matsuda
- Journal Title
  
  Front.Biosci.(Schol.Ed.)
  
  Volume: S3 Issue: 1 Pages: 1463-1477
- DOI
  10.2741/237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591555, KAKENHI-PROJECT-22790378, KAKENHI-PROJECT-221S0001
[Journal Article] Germline alterations of the CDH1 gene in familial gastric cancer in the Japanese population2011
- Author(s)
  Yamada H, et.al
- Journal Title
  
  Cancer Science
  
  Volume: 102 Issue: 10 Pages: 1782-1788
- DOI
  10.1111/j.1349-7006.2011.02038.x
- NAID
  10030243664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790383, KAKENHI-PROJECT-22659072, KAKENHI-PROJECT-22790378, KAKENHI-PROJECT-221S0001
[Journal Article] Aberrant expression and mutation-inducing activity of AID in human lung cancer2011
- Author(s)
  Shinmura K, Igarashi H, Goto M, Tao H, Yamada H, Matsuura S, Tajima M, Matsuda T, Yamane A, Funai K, Tanahashi M, Niwa H, Ogawa H, Sugimura H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 18 Issue: 7 Pages: 2084-2092
- DOI
  10.1245/s10434-011-1568-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590356, KAKENHI-PROJECT-22790378, KAKENHI-PROJECT-23221006
[Journal Article] Adenine DNA glycosylase activity of 14 human Mutr homolog(MUTYH)variant proteins found in patients with colorectal polyposis and cancer2010
- Author(s)
  後藤正憲、和也新村、中別府雄作、陶弘、山田英孝、常吉俊宏、椙村春彦
- Journal Title
  
  HUMAN MUTATION
  
  Volume: 31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790378
[Journal Article] Three novel NEIL1 promoter polymorphisms in gastric cancer patients2010
- Author(s)
  Goto M, Shinmura K, Tao H, Tsugane S, Sugimura H
- Journal Title
  
  World J Gastrointest Oncol
  
  Volume: 2 Issue: 2 Pages: 117-120
- DOI
  10.4251/wjgo.v2.i2.117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790378
[Journal Article] Adenine DNA glycosylase activity of 14 Human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer2010
- Author(s)
  Goto M, Shinmura K, Nakabeppu Y, Tao H, Yamada H, Tsuneyoshi T, Sugimura H
- Journal Title
  
  Hum Mutat
  
  Volume: 31 Issue: 11 Pages: 1861-1874
- DOI
  10.1002/humu.21363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590356, KAKENHI-PROJECT-22790378
[Presentation] 血小板由来微小胞による肝腫瘍細胞の生存能促進2022
- Author(s)
  田中　宏樹、上小倉　佑機、後藤　正憲、藤井　裕美子、西川　祐司
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 慢性肝障害から発生する肝発癌におけるエピゲノム異常2022
- Author(s)
  Hiroki Tanaka, Masanori Goto, Yumiko Fujii, Yuki Kamikokura, Yuji Nishikawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 肝細胞がんにおけるがん遺伝子Mycとプロリン代謝酵素PRODHの関連2022
- Author(s)
  後藤　正憲、田中　宏樹、藤井　裕美子、上小倉　佑機、岡田　陽子、西川　祐司
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 血小板－肝細胞相互作用：ラット肝細胞による血小板由来微小胞の取り込み2022
- Author(s)
  田中　宏樹、堀岡　希衣、後藤　正憲、上小倉　佑機、西川　祐司
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 活性型 AKT と YAP で誘導したマウス胆管癌表現型に対する Myc または Mycn の影響2022
- Author(s)
  後藤　正憲、田中　宏樹、藤井　裕美子、上小倉　佑機、岡田　陽子、西川　祐司
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝腫瘍のNotch経路の活性化と胆管癌表現型に対するMycとMycnの影響2022
- Author(s)
  Masanori Goto, Hiroki Tanaka, Yumiko Fujii, Yuki Kamikokura, Yoko Okada, and Yuji Nishikawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 肝内胆管細胞における脂質ホスファターゼ SHIP2 の細胞核への集積2022
- Author(s)
  藤井　裕美子、上小倉　佑機、後藤　正憲、人見　淳一、田中　宏樹、岡田　陽子、西川　祐司
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝再生における Myc 依存性、Myc 非依存性の肝細胞増殖機構2021
- Author(s)
  後藤正憲、大塩貴子、山本雅大、藤井裕美子、田中宏樹、上小倉佑機、孟玲童、岡田陽子、西川祐司
- Organizer
  第28回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Targeting effect of the autologous platelet-based drug delivery system on hepatocellular carcinoma2021
- Author(s)
  Hiroki Tanaka , Kie Horioka , Masanori Goto , Junichi Hitomi , Yumiko Fujii , Yuki Kamikokura , Lingtong Meng , Katsuhiro Ogawa , Yuji Nishikawa
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス慢性肝傷害に伴う Myc に依存しない肝細胞増殖メカニズム2021
- Author(s)
  後藤正憲、大塩貴子、山本雅大、藤井裕美子、上小倉佑機、孟玲童、岡田陽子、西川祐司
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 分化転換および脱分化による混合型肝癌の発生：肝細胞特異的p53ノックアウトマウスを用いた検討2021
- Author(s)
  西川祐司，劉洋，辛氷，山本雅大，大塩貴子，後藤正憲，上小倉佑機，田中宏樹，孟玲童，岡田陽子，水上祐輔
- Organizer
  第57回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 自己血小板によるドラッグデリバリーシステム―肝癌・血小板相互作用を利用した新たな治療戦略―2021
- Author(s)
  田中　宏樹、堀岡　希衣、後藤正憲、人見淳一、藤井　裕美子、上小倉　佑機、孟　玲童、小川　勝洋、西川　祐司
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Myc-independent hepatocyte proliferation in chronic liver injury: possible involvement of altered proline metabolism2021
- Author(s)
  Masanori Goto, Takako Ooshio, Masahiro Yamamoto, Yuki Kamikokura, Yoko Okada, Yuji Nishikawa
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 非アルコール性脂肪肝炎の進展における門脈循環障害の意義2021
- Author(s)
  西川祐司、孟玲童、後藤正憲、田中宏樹、上小倉佑機、藤井裕美子、岡田陽子、古川博之
- Organizer
  第28回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] p53ノックアウトマウス肝細胞のin vitro形質転換による胆管癌および混合型肝癌細胞株の樹立2020
- Author(s)
  上小倉佑機、後藤正憲、人見淳一、藤井裕美子、田中宏樹、渡邉賢二、大塩貴子、山本雅大、孟玲童、岡田陽子、西川祐司
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] ストレスキナーゼ MKK7の肝傷害後の修復における役割：ウロキナーゼ型プラスミノーゲンアクティベーター活性化の関与2020
- Author(s)
  西川祐司、大塩貴子、山本雅大、藤井清永、辛氷、渡邉賢二、後藤正憲、岡田陽子、鈴木聡、Penninger Josef、仁科博史
- Organizer
  第27回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 非アルコール性脂肪性肝疾患の進展に対する門脈循環障害の影響2020
- Author(s)
  孟玲童，後藤正憲，上小倉佑機，田中宏樹，藤井裕美子，人見淳一，岡田陽子，西川祐司
- Organizer
  第53回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 非アルコール性脂肪性肝疾患の進展に対する門脈循環障害の影響2020
- Author(s)
  孟玲童、後藤正憲、上小倉佑機、藤井裕美子、人見淳一、岡田陽子、西川祐司
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝再生におけるMyc依存性および非依存性肝細胞増殖メカニズムの検討2020
- Author(s)
  後藤正憲，大塩貴子，山本雅大，人見淳一，藤井裕美子，上小倉佑機，孟玲童，岡田陽子，西川祐司
- Organizer
  第53回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 腫瘍・血小板相互作用を利用した肝癌に対する新規治療法2020
- Author(s)
  田中宏樹，堀岡希衣，後藤正憲，人見淳一，藤井裕美子，上小倉佑機，孟玲童，小川勝洋，西川祐司
- Organizer
  第122回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝再生におけるMyc依存性および非依存性肝細胞増殖メカニズム2020
- Author(s)
  後藤正憲、大塩貴子、山本雅大、人見淳一、藤井裕美子、上小倉佑機、孟玲童、岡田陽子、西川祐司
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] p53欠損マウス肝細胞のin vitro形質転換：肝内移植で形成される腫瘍の表現型と間質の状態変化の関連2020
- Author(s)
  上小倉佑機，後藤正憲，人見淳一，藤井裕美子，田中宏樹，渡邉賢二，大塩貴子，山本雅大，孟玲童，岡田陽子，西川祐司
- Organizer
  第122回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Myc阻害蛋白発現による部分肝切除後の肝細胞増殖抑制2019
- Author(s)
  後藤正憲，大塩貴子，上小倉佑機，孟玲童，岡田陽子，西川祐司
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 肝再生における癌遺伝子Mycの役割：in vivoにおけるMyc抑制系を用いた検討2019
- Author(s)
  後藤正憲，大塩貴子，山本雅大，上小倉祐機，孟玲童，岡田陽子，西川祐司
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝腫瘍における胎児期・新生児期遺伝子の発現：癌遺伝子活性に伴うエピゲノム変化2019
- Author(s)
  西川祐司，渡邉賢二，山本雅大，辛氷，大塩貴子，後藤正憲，藤井清永，劉洋，岡田陽子，川博之
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Myc contributes to hepatocyte proliferation following a partial hepatectomy in mice2019
- Author(s)
  Masanori Goto, Takako Ooshio, Masahiro Yamamoto, Yuji Nishikawa
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] NotchおよびRAS経路活性化による肝細胞からの肉腫様肝癌の誘導2019
- Author(s)
  西川祐司，山本雅大，大塩貴子，辛氷，後藤正憲，上小倉佑機，孟玲童，岡田陽子
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 肝細胞から胆管細胞への分化転換におけるNotch経路と上皮間葉転換の関与2019
- Author(s)
  大塩　貴子，山本雅大，後藤正憲，上小倉佑機，孟玲童，岡田陽子，西川祐司
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 成熟マウス肝細胞のin vitro形質転換による移植可能な胆管癌モデルの開発2019
- Author(s)
  上小倉　佑機，後藤　正憲，渡邉　賢二，大塩貴子，山本　雅大，孟　玲童，岡田　陽子，西川　祐司
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 成熟マウス肝細胞のin vitro形質転換による同所移植可能な胆管癌モデルの開発2019
- Author(s)
  上小倉佑機、後藤正憲、渡邉賢二、大塩貴子、山本雅大、人見淳一、藤井裕美子、孟玲童、岡田陽子、西川祐司
- Organizer
  第16回日本病理学会カンファレンス
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 胃癌における MUTYH の 8-hydroxyguanine 誘発変異抑制活性とその発現レベルの予後予測に関する検討2012
- Author(s)
  新村和也、後藤正憲、鈴木雅也、陶弘、山田英孝、五十嵐久喜、松浦駿、前田松喜、今野弘之、松田知成、椙村春彦
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] 癌における MUTYH の 8-hydroxyguanine 誘発変異抑制活性とその発現レベルの予後予測に関する検討2012
- Author(s)
  新村和也、後藤正憲、椙村春彦
- Organizer
  第65回日本酸化ストレス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] Germline alterations o the CDH1 gene in familial gastric cancer in the Japaese population2012
- Author(s)
  Yamada H, Shinmura K, Ito H, Kasami H, Sasaki N, Shima H, Tao H, Goto M, Du C, Tsuneyoshi T, Tanioka F, Sugimura H
- Organizer
  71th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] Aberrant expression and mutation-inducing activity of AID in human lung cancer2011
- Author(s)
  Shinmura K, Igarashi H, Goto M, Tao H, Yamada H, Matsuura S, Matsuda T, Ogawa H, Sugimura H
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] 大腸ポリポーシスと大腸がんの患者で見つかった 14 種の MUTYH 変異型タンパク質の活性と局在の評価2011
- Author(s)
  後藤正憲、新村和也、中別府雄作、陶弘、山田英孝、常吉俊宏、椙村春彦
- Organizer
  がん予防大会 2011(第18回日本がん予防学会、第34回日本がん疫学分子疫学研究会)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] The activity and localization of 14 MUTYH variant proteins found in patients with colorectal polyposis and cancer2011
- Author(s)
  Goto M, Shinmura K, Nakabeppu Y, Tao H, Yamada H, Tsuneyoshi T, Sugimura H
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] ヒト肺癌における脱アミノ化酵素 AID の異常発現と変異誘導能2011
- Author(s)
  新村和也、五十嵐久喜、後藤正憲、陶弘、山田英孝、松浦駿、小川博、椙村春彦
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] 大腸ポリポーシスと大腸がん患者の中で見つかった14種のMUTYH変異型多タンパク質の活性と局在の評価2011
- Author(s)
  後藤正憲、和也新村、中別府雄作、陶弘、山田英孝、常吉俊宏、椙村春彦
- Organizer
  がん予防大会2011京都
- Place of Presentation
  京都府立医科大学
- Year and Date
  2011-06-21
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] The activity and localization of 14 MUTYH variant proteins found in patients with colorectal polyposis and cancer2011
- Author(s)
  後藤正憲、和也新村、中別府雄作、陶弘、山田英孝、常吉俊宏、椙村春彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] Altered expression and the missense polymorphism of the human base excision repair gene NTH1 in gastric cancer2010
- Author(s)
  Goto M, Shinmura K, Konno H, Sugimura H
- Organizer
  101th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] Absence of germline mono-allelic promoter hypermethylation of the CDH1 gene in gastric cancer patients2010
- Author(s)
  Yamada H, Shinmura K, Mori H, Goto M, Iwaizumi M, Konno H, Kataoka H,Yamada M, Ozawa T, Tsuneyoshi T, Tanioka F, Sugimura H
- Organizer
  69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-22790378
[Presentation] Altered expression and the missense polymorphism of the human bas-e excision repair gene NTH1 in gastric cancer2010
- Author(s)
  後藤正憲、新村和也、今野弘之、椙村春彦
- Organizer
  第101回米国癌研究会議(AACR)
- Place of Presentation
  ワシントンDC
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-22790378

1. Nishikawa Yuji (90208166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 33 results
2. 藤井裕美子 (30722334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
3. 田中宏樹 (70596155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
4. 人見淳一 (40568664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. YAMADA Hidetaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. ISHIJIMA Muneaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 林明宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 松島芳隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 新村和也

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 鈴木聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山本雅大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

GOTO Masanori 後藤 正憲

後藤 正憲 ゴトウ マサノリ

Research Projects

Research Products

Co-Researchers

Mechanisms determining the wide spectrum of hepatocytic tumors

Principal Investigator

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Review Section

Research Institution

The investigation of the association between variants of the base excision repair(BER) enzymes and carcinogenesis, and the repair activities of BER enzymes against etheno-DNA adductsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] High levels of Myc expression are required for the robust proliferation of hepatocytes, but not for the sustained weak proliferation2023

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[Journal Article] Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway2022

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[Journal Article] Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice2021

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[Journal Article] Generation of combined hepatocellular‐cholangiocarcinoma through transdifferentiation and dedifferentiation in p53‐knockout mice2021

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[Journal Article] Hepatocyte MKK7 Contributes to Restoration of the Liver Parenchyma Following Injury2020

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[Journal Article] Low bone mineral density due to secondary hyperparathyroidism in theGlatmTg(CAG‐A4GALT)mouse model of Fabry disease2020

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[Journal Article] Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations2019

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[Journal Article] Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis2012

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[Journal Article] Lipid peroxidation-induced DNA adducts in human gastric mucosa2012

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[Journal Article] Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer2011

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[Journal Article] Genetic susceptibility to lung cancer2011

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[Journal Article] Germline alterations of the CDH1 gene in familial gastric cancer in the Japanese population2011

Author(s)

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NAID

Data Source

[Journal Article] Aberrant expression and mutation-inducing activity of AID in human lung cancer2011

Author(s)

GOTO Masanori 後藤正憲

後藤正憲ゴトウマサノリ

[Presentation] 活性型 AKT と YAP で誘導したマウス胆管癌表現型に対する Myc または Mycn の影響2022