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Kanagawa Motoi  金川 基

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KANAGAWA Motoi  金川 基

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Researcher Number 00448044
Other IDs
Affiliation (Current) 2025: 愛媛大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2020 – 2025: 愛媛大学, 医学系研究科, 教授
2019: 神戸大学, 医学研究科, 客員教授
2016 – 2018: 神戸大学, 医学研究科, 講師
2011 – 2016: 神戸大学, 医学(系)研究科(研究院), 講師
2014: 神戸大学, 医学研究科, 助教 … More
2013: 神戸大学, 大学院・医学研究科, 助教
2012: 神戸大学, 医学研究科, 助教
2012: 神戸大学, 医学研究科, 講師
2012: 神戸大学, 大学院・医学研究科, 講師
2009 – 2010: Kobe University, 医学研究科, 助教
2009 – 2010: 神戸大学, 大学院・医学研究科, 助教
2008: Osaka University, 特任助教(常勤), 特任助教(常勤)
2007 – 2008: Osaka University, 医学系研究科, 特任助教(常勤) Less
Review Section/Research Field
Principal Investigator
Basic Section 48040:Medical biochemistry-related / Functional biochemistry / Biological Sciences / Pathological medical chemistry / Medium-sized Section 48:Biomedical structure and function and related fields / Transformative Research Areas, Section (III) / Medium-sized Section 52:General internal medicine and related fields / Neurology / Biological Sciences
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related … More / Medium-sized Section 52:General internal medicine and related fields / Biomedical engineering/Biomaterial science and engineering / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90110:Biomedical engineering-related / Biological Sciences / Neurology / General anatomy (including Histology/Embryology) / Dental engineering/Regenerative dentistry / Biomedical engineering/Biological material science Less
Keywords
Principal Investigator
筋ジストロフィー / ジストログリカン / 糖鎖 / フクチン / リビトールリン酸 / 神経 / 細胞・組織 / ジスフェルリン / 膜修復 / 糖鎖異常 … More / マトリックス受容体 / リビトール / 疾患モデル / 糖鎖生物学 / 脳病変 / 翻訳後修飾 / 筋再生 / 遺伝子治療 / 基底膜 / 中枢神経障害 / 脳形成障害 / 細胞膜修復 / 神経分子病態学 / 筋形成・維持 / 筋形成維持 / 福山型筋ジストロフィー / ジスクェルリン / 細胞膜 / モデルマウス / 分子病態学 / 糖鎖治療 … More
Except Principal Investigator
メカノセンサー / 心不全 / 心肥大 / メカニカルストレス / 心臓 / 血行動態負荷 / 心筋細胞 / 福山型筋ジストロフィー / カルシウム / 筋疾患 / 筋再生 / レニン・アンジオテンシン系 / 分子標的治療 / AAV遺伝子治療 / アンチセンス核酸 / 機械受容 / 介在板 / TRPV2 / リビトールリン酸 / ジストログリカン / トランスレーショナルリサーチ / 遺伝子 / 生理学 / 循環器・高血圧 / 二光子レーザー / 膜融合 / アネキシン / 小胞輸送 / 筋ジストロフィー / MICAL / 細胞膜損傷 / 細胞膜修復 / 筋疾患治療 / 筋萎縮 / AT2受容体 / 福山型金ジストロフィー / リビトール補充療法 / リビトールリン酸異常症 / 可視化 / シグナル / GCaMP6s / メカノトランスダクション / 機能的成熟 / Ca / 適応 / 膜修復 / 血管 / 感覚神経 / 侵害受容 / 筋痛 / 運動適応 / 骨格筋 / 生体分子 / ストレス / TRPチャネル / ノックアウトマウス / Ca2+ハンドリング / 再構築 / 成熟・分化 / 多階層 / 翻訳後修飾 / ゴルジ体キナーゼ / ゾーン形成因子 / オルガネラ・ゾーン / ゴルジキナーゼ / リン酸修飾 / 糖鎖修飾 / 小胞体 / ゴルジ体 / 転写調節 / LAD / 核ラミナ / PIGB / 修飾ゾーン / リン酸化 / GPI / 分子生理 / 高血圧 / 血行動態 / タンパク質 / チャネル / リモデリング / ポストリン酸構造 / フクチン / アンチセンス治療 / ジストログリカノパチー / レトロトランスポゾン / 小胞融合 / 細胞膜修復装置 / イカ巨大神経 / 細胞機能形態学(細胞膜修復) / MICAL1 / エクトゾーム / ライブイメージング / 二光子 / dysferlin / Annexin / チャネル・トランスポーター / Ca2+輸送体 Less
  • Research Projects

    (26 results)
  • Research Products

    (147 results)
  • Co-Researchers

    (42 People)
  •  新規翻訳後修飾体リビトールリン酸の修飾機序と生理的・病的意義の解明Principal Investigator

    • Principal Investigator
      金川 基
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Ehime University
  •  筋の健常性維持におけるAT2型受容体の生理的役割の解明と筋疾患治療への応用

    • Principal Investigator
      岩波 純
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Ehime University
  •  骨格筋の可塑性を制御するジストログリカン-ECM情報伝達経路の解明Principal Investigator

    • Principal Investigator
      金川 基
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Ehime University
  •  福山型筋ジス及びDG異常症のアンチセンス核酸、糖鎖補充、AAV治療、胎児治療開発

    • Principal Investigator
      戸田 達史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      The University of Tokyo
  •  筋ジストロフィー胎児治療の可能性を探るPrincipal Investigator

    • Principal Investigator
      金川 基
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Ehime University
  •  The effect of renin-angiotensin system in mentenance of skeltal muscle and diseases

    • Principal Investigator
      Iwanami Jun
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Ehime University
  •  Elucidation of the molecular basis of novel ribitol phosphate modifications and their application to the development of treatments for muscular dystrophyPrincipal Investigator

    • Principal Investigator
      Kanagawa Motoi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Ehime University
  •  Monitoring of the activity of cardiac mechanosensor

    • Principal Investigator
      片野坂 友紀
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Kinjo Gakuin University
      Okayama University
  •  Pathogenesis and Antisense nucleic acid, glycosylation supplementation, and AAV therapy development forFukuyama muscular dystrophy and related diseases

    • Principal Investigator
      TODA Tatsushi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      The University of Tokyo
  •  Understanding of the mechanism of ribitol-phosphate modification and application of its physiological function to therapyPrincipal Investigator

    • Principal Investigator
      Kanagawa Motoi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Ehime University
      Kobe University
  •  Elucidation of the mechanisms underlying muscle adaptation to exercise via neuromuscular crosstalk based on biomedical engineering analysis.

    • Principal Investigator
      Katanosaka Kimiaki
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Chubu University
  •  Mechanism and function of posttranslational modification zones

    • Principal Investigator
      Goto Satoshi
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Rikkyo University
  •  Mechanotransduction on cardiac physiology

    • Principal Investigator
      KATANOSAKA YUKI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Okayama University
  •  Elucidation of structure, modification mechanism, pathophysiological roles of a novel posttranslational modification, post-phosphoryl sugar chainPrincipal Investigator

    • Principal Investigator
      Kanagawa Motoi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University
  •  脳形成・神経機能に関わる新しい機能ドメイン“ポストリン酸糖鎖”の確立Principal Investigator

    • Principal Investigator
      金川 基
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Elucidation of molecular mechanism of mechanotransduction in the heart

    • Principal Investigator
      Katanosaka Yuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Okayama University
  •  ジストログリカンに見出されたユニークな機能ドメインの作動原理と神経生物学的な役割Principal Investigator

    • Principal Investigator
      金川 基
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Structural, functional, and pathological studies on a novel "post-phosphoryl sugar chain"Principal Investigator

    • Principal Investigator
      KANAGAWA Motoi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University
  •  Molecular targeting therapy and pathomechanism for Fukuyama muscular dystrophy and related disorders

    • Principal Investigator
      TATSUSHI Toda
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      Kobe University
  •  Abnormal membranerepair as a new concept for muscular dystrophy and search for new disease genesPrincipal Investigator

    • Principal Investigator
      KANAGAWA Motoi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Kobe University
  •  Live Imaging of membrane repair by high sensitive multi-photon laser microscope in vivo system.

    • Principal Investigator
      MIYAKE Katsuya
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Kagawa University
  •  Live Imaging for Two-photon microscopy: Membrane repair in Squid Gian Axon.

    • Principal Investigator
      MIYAKE Katsuya
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Kagawa University
  •  マルチレベル医工学評価法に基づく心筋メカノセンサーの作動機序と病態生理的役割

    • Principal Investigator
      Katanosaka Yuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Okayama University
  •  細胞膜安定性維持システムの破綻によるトランスポートソーム異常と病態Principal Investigator

    • Principal Investigator
      金川 基
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
      Osaka University
  •  Role of fukutin-dependent glycosylation of dystroglycan on skeletal muscle development, maintenance, and muscular dystrophy pathogenesisPrincipal Investigator

    • Principal Investigator
      KANAGAWA Motoi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kobe University
  •  Molecular pathogenesis and therapeutic strategy of congenitalmuscular dystrophies with glycosylation defectsPrincipal Investigator

    • Principal Investigator
      KANAGAWA Motoi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent Other

  • [Book] Glycoscience Lab Manual2008

    • Author(s)
      金川 基
    • Publisher
      Elsevier Science Publishers
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Book] Experimental Glycoscience (Taniguchi, N., Suzuki, A., Ito, Y., Narimatsu, H., Kawasaki, T., and Hase, S. eds.)2008

    • Author(s)
      Kanagawa, M., and Toda, T. Fukutin and Fukuyama congenital muscular dystrophy.
    • Publisher
      Springer, Tokyo
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Journal Article] Chain-specificity of laminin α1-5 LG45 modules in the recognition of carbohydrate-linked receptors and intramolecular binding2023

    • Author(s)
      Matsunuma Masumi、Kan Ryuji、Yamada Yuji、Hamada Keisuke、Kanagawa Motoi、Nomizu Motoyoshi、Kikkawa Yamato
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 10430-10430

    • DOI

      10.1038/s41598-023-37533-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K07728, KAKENHI-PROJECT-21K06563, KAKENHI-PROJECT-21H02685
  • [Journal Article] Endogenous reductase activities for the generation of ribitol-phosphate, a CDP-ribitol precursor, in mammals2023

    • Author(s)
      Hoshino Shunsuke、Manya Hiroshi、Imae Rieko、Kobayashi Kazuhiro、Kanagawa Motoi、Endo Tamao
    • Journal Title

      The Journal of Biochemistry

      Volume: 175 Issue: 4 Pages: 418-425

    • DOI

      10.1093/jb/mvad115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K06110, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-21H02685, KAKENHI-PROJECT-23K24244, KAKENHI-PROJECT-23K27328
  • [Journal Article] CDP-ribitol prodrug treatment ameliorates ISPD-deficient muscular dystrophy mouse model2022

    • Author(s)
      Tokuoka Hideki、Imae Rieko、Nakashima Hitomi、Manya Hiroshi、Masuda Chiaki、Hoshino Shunsuke、Kobayashi Kazuhiro、Lefeber Dirk J.、Matsumoto Riki、Okada Takashi、Endo Tamao、Kanagawa Motoi、Toda Tatsushi
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 1847-1847

    • DOI

      10.1038/s41467-022-29473-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-22K19509, KAKENHI-PROJECT-20H00526, KAKENHI-PROJECT-21H02685, KAKENHI-PROJECT-19K07058, KAKENHI-WRAPUP-22H04899, KAKENHI-PROJECT-23K20328, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-23K24244
  • [Journal Article] Laminin α5_CD239_Spectrin is a candidate association that compensates the linkage between the basement membrane and cytoskeleton in skeletal muscle fibers2022

    • Author(s)
      Kikkawa Yamato、Matsunuma Masumi、Kan Ryuji、Yamada Yuji、Hamada Keisuke、Nomizu Motoyoshi、Negishi Yoichi、Nagamori Shushi、Toda Tatsushi、Tanaka Minoru、Kanagawa Motoi
    • Journal Title

      Matrix Biology Plus

      Volume: 15 Pages: 100118-100118

    • DOI

      10.1016/j.mbplus.2022.100118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00526, KAKENHI-PROJECT-21H02685, KAKENHI-PROJECT-21H03365, KAKENHI-PROJECT-20K07622
  • [Journal Article] Muscle Transcriptomics Shows Overexpression of Cadherin 1 in Inclusion Body Myositis2022

    • Author(s)
      Chiseko Ikenaga, Hidetoshi Date, Motoi Kanagawa, Jun Mitsui, Hiroyuki Ishiura, Jun Yoshimura, Iago Pinal-Fernandez, Andrew L Mammen, Thomas E Lloyd , Shoji Tsuji, Jun Shimizu, Tatsushi Toda, Jun Goto
    • Journal Title

      Ann Neurol.

      Volume: 91 Issue: 3 Pages: 317-328

    • DOI

      10.1002/ana.26304

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07956, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20H00526
  • [Journal Article] Dystroglycanopathy: From Elucidation of Molecular and Pathological Mechanisms to Development of Treatment Methods2021

    • Author(s)
      Kanagawa Motoi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 23 Pages: 13162-13162

    • DOI

      10.3390/ijms222313162

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00526
  • [Journal Article] TRPV2 is involved in induction of lubricin and suppression of ectopic endochondral ossification in articular joints2021

    • Author(s)
      Nakamoto Hideki、Katanosaka Yuki、Chijimatsu Ryota、Mori Daisuke、Xuan Fengjun、Yano Fumiko、Omata Yasunori、Maenohara Yuji、Murahashi Yasutaka、Kawaguchi Kohei、Yamagami Ryota、Inui Hiroshi、Taketomi Shuji、Taniguchi Yuki、Kanagawa Motoi、Naruse Keiji、Tanaka Sakae、Saito Taku
    • Journal Title

      Arthritis & Rheumatology

      Volume: - Issue: 8 Pages: 1441-1450

    • DOI

      10.1002/art.41684

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-21H04960, KAKENHI-PROJECT-20H03799, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-21K09294, KAKENHI-PROJECT-20K20644, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-18K09019
  • [Journal Article] Galectin 3?binding protein suppresses amyloid-β production by modulating β-cleavage of amyloid precursor protein2020

    • Author(s)
      Seki Tsuneyoshi、Kanagawa Motoi、Kobayashi Kazuhiro、Kowa Hisatomo、Yahata Naoki、Maruyama Kei、Iwata Nobuhisa、Inoue Haruhisa、Toda Tatsushi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Issue: 11 Pages: 3678-3691

    • DOI

      10.1074/jbc.ra119.008703

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07354, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-19H00597
  • [Journal Article] Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy.2020

    • Author(s)
      Kuwabara N, Imae R, Manya H, Tanaka T, Mizuno M, Tsumoto H, Kanagawa M, Kobayashi K, Toda T, Senda T, Endo T, Kato R.
    • Journal Title

      Nat Commun.

      Volume: 11 Issue: 1 Pages: 303-303

    • DOI

      10.1038/s41467-019-14220-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07058, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-17H06264
  • [Journal Article] Lactone-Driven Ester-to-Amide Derivatization for Sialic Acid Linkage-Specific Alkylamidation2020

    • Author(s)
      Jun-Ichi Furukawa 1, Hisatoshi Hanamatsu 2, Takashi Nishikaze 3, Hiroshi Manya 4, Nobuaki Miura 5, Hirokazu Yagi 6, Ikuko Yokota 1, Keiko Akasaka-Manya 4, Tamao Endo 4, Motoi Kanagawa 7 8, Norimasa Iwasaki 1, Koichi Tanaka 3
    • Journal Title

      Anal Chem .

      Volume: 3 Issue: 21 Pages: 14383-14392

    • DOI

      10.1021/acs.analchem.0c02209

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08443, KAKENHI-PROJECT-19K07883, KAKENHI-PROJECT-19K15597, KAKENHI-PROJECT-18H02616, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-19H05648
  • [Journal Article] Congenital hearing impairment associated with peripheral cochlear nerve dysmyelination in glycosylation-deficient muscular dystrophy2020

    • Author(s)
      Morioka Shigefumi、Sakaguchi Hirofumi、Mohri Hiroaki、Taniguchi-Ikeda Mariko、Kanagawa Motoi、Suzuki Toshiaki、Miyagoe-Suzuki Yuko、Toda Tatsushi、Saito Naoaki、Ueyama Takehiko
    • Journal Title

      PLOS Genetics

      Volume: 16 Issue: 5 Pages: 1-28

    • DOI

      10.1371/journal.pgen.1008826

    • NAID

      120006863578

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-20H00526, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-18K07790, KAKENHI-PROJECT-18K09383, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-19K07519
  • [Journal Article] Characterization of dystroglycan binding in adhesion of human induced pluripotent stem cells to laminin-511 E8 fragment2019

    • Author(s)
      Sugawara Yumika、Hamada Keisuke、Yamada Yuji、Kumai Jun、Kanagawa Motoi、Kobayashi Kazuhiro、Toda Tatsushi、Negishi Yoichi、Katagiri Fumihiko、Hozumi Kentaro、Nomizu Motoyoshi、Kikkawa Yamato
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 1-12

    • DOI

      10.1038/s41598-019-49669-x

    • NAID

      120006728095

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06637, KAKENHI-PROJECT-18K12085, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-18H02873, KAKENHI-PROJECT-17K01954, KAKENHI-PROJECT-17K07180
  • [Journal Article] Myo-Glyco disease Biology: Genetic Myopathies Caused by Abnormal Glycan Synthesis and Degradation2019

    • Author(s)
      Kanagawa Motoi
    • Journal Title

      Journal of Neuromuscular Diseases

      Volume: - Issue: 2 Pages: 1-13

    • DOI

      10.3233/jnd-180369

    • NAID

      120006888540

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-18H02616
  • [Journal Article] Wide distribution of alpha-synuclein oligomers in multiple system atrophy brain detected by proximity ligation2019

    • Author(s)
      Sekiya Hiroaki、Kowa Hisatomo、Koga Hinako、Takata Mariko、Satake Wataru、Futamura Naonobu、Funakawa Itaru、Jinnai Kenji、Takahashi Motonori、Kondo Takeshi、Ueno Yasuhiro、Kanagawa Motoi、Kobayashi Kazuhiro、Toda Tatsushi
    • Journal Title

      Acta Neuropathologica

      Volume: 137 Issue: 3 Pages: 455-466

    • DOI

      10.1007/s00401-019-01961-w

    • NAID

      120006599160

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-16H05353
  • [Journal Article] Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure2019

    • Author(s)
      Ujihara Yoshihiro、Kanagawa Motoi、Mohri Satoshi、Takatsu Satomi、Kobayashi Kazuhiro、Toda Tatsushi、Naruse Keiji、Katanosaka Yuki
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 5754-5754

    • DOI

      10.1038/s41467-019-13623-2

    • NAID

      120006777089

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H02085, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-17H04740
  • [Journal Article] In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson’s disease2018

    • Author(s)
      Uenaka Takeshi、Satake Wataru、Cha Pei-Chieng、Hayakawa Hideki、Baba Kousuke、Jiang Shiying、Kobayashi Kazuhiro、Kanagawa Motoi、Okada Yukinori、Mochizuki Hideki、Toda Tatsushi
    • Journal Title

      Human Molecular Genetics

      Volume: 27 Pages: 3974-3985

    • DOI

      10.1093/hmg/ddy279

    • NAID

      120006549191

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19512, KAKENHI-PUBLICLY-17H05700, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-17H04056
  • [Journal Article] Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors2018

    • Author(s)
      Orlandi Cesare、Omori Yoshihiro、Wang Yuchen、Cao Yan、Ueno Akiko、Roux Michel J.、Condomitti Giuseppe、de Wit Joris、Kanagawa Motoi、Furukawa Takahisa、Martemyanov Kirill A.
    • Journal Title

      Cell Reports

      Volume: 25 Issue: 1 Pages: 130-145

    • DOI

      10.1016/j.celrep.2018.08.068

    • NAID

      120006531168

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-16K08583
  • [Journal Article] Ribitol-phosphate-a newly identified posttranslational glycosylation unit in mammals: structure, modification enzymes and relationship to human diseases2018

    • Author(s)
      Kanagawa Motoi、Toda Tatsushi
    • Journal Title

      The Journal of Biochemistry

      Volume: 163 Issue: 5 Pages: 359-369

    • DOI

      10.1093/jb/mvy020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04352, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-18H02616
  • [Journal Article] Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation2018

    • Author(s)
      Tsuchiya Masaki、Hara Yuji、Okuda Masaki、Itoh Karin、Nishioka Ryotaro、Shiomi Akifumi、Nagao Kohjiro、Mori Masayuki、Mori Yasuo、Ikenouchi Junichi、Suzuki Ryo、Tanaka Motomu、Ohwada Tomohiko、Aoki Junken、Kanagawa Motoi、Toda Tatsushi、Nagata Yosuke、Matsuda Ryoichi、Takayama Yasunori、Tominaga Makoto、Umeda Masato
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 2049-2049

    • DOI

      10.1038/s41467-018-04436-w

    • NAID

      120006471161

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K11089, KAKENHI-PROJECT-17K15793, KAKENHI-PLANNED-15H05930, KAKENHI-PUBLICLY-17H06012, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-15H02501, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H04786, KAKENHI-PROJECT-17H03805, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-16KT0070, KAKENHI-PROJECT-16K14729
  • [Journal Article] CDP-glycerol inhibits the synthesis of the functionalO-mannosyl glycan of α-dystroglycan2018

    • Author(s)
      Imae Rieko、Manya Hiroshi、Tsumoto Hiroki、Osumi Kenji、Tanaka Tomohiro、Mizuno Mamoru、Kanagawa Motoi、Kobayashi Kazuhiro、Toda Tatsushi、Endo Tamao
    • Journal Title

      Journal of Biological Chemistry

      Volume: 293 Issue: 31 Pages: 12186-12198

    • DOI

      10.1074/jbc.ra118.003197

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-16K20996
  • [Journal Article] Cell endogenous activities of fukutin and FKRP coexist with the ribitol xylosyltransferase, TMEM5.2018

    • Author(s)
      Nishihara, R., Kobayashi, K., Imae, R., Tsumoto, H., Manya, H., Mizuno, M., Kanagawa, M., Endo, T., and Toda, T.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 497 Issue: 4 Pages: 1025-1030

    • DOI

      10.1016/j.bbrc.2018.02.162

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-16K20996, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-15H04352, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H03987
  • [Journal Article] Temporal requirement of dystroglycan glycosylation during brain development and rescue of severe cortical dysplasia via gene delivery in the fetal stage2018

    • Author(s)
      Sudo Atsushi、Kanagawa Motoi、Kondo Mai、Ito Chiyomi、Kobayashi Kazuhiro、Endo Mitsuharu、Minami Yasuhiro、Aiba Atsu、Toda Tatsushi
    • Journal Title

      Human molecular genetics

      Volume: 27 Issue: 7 Pages: 1174-1185

    • DOI

      10.1093/hmg/ddy032

    • NAID

      120006459805

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25115010, KAKENHI-PROJECT-15H04352, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H05152, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-18H02616
  • [Journal Article] Muscular Dystrophy with Ribitol-Phosphate Deficiency: A Novel Post-Translational Mechanism in Dystroglycanopathy2017

    • Author(s)
      Kanagawa Motoi、Toda Tatsushi
    • Journal Title

      Journal of Neuromuscular Diseases

      Volume: 4 Issue: 4 Pages: 259-267

    • DOI

      10.3233/jnd-170255

    • NAID

      120006811130

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26253057, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-15H04352, KAKENHI-PROJECT-17H01563
  • [Journal Article] The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle2017

    • Author(s)
      Kamizaki Koki、Doi Ryosuke、Hayashi Makoto、Saji Takeshi、Kanagawa Motoi、Toda Tatsushi、Fukada So-ichiro、Ho Hsin-Yi Henry、Greenberg Michael Eldon、Endo Mitsuharu、Minami Yasuhiro
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Issue: 38 Pages: 15939-15951

    • DOI

      10.1074/jbc.m117.785709

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253057, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-15H04352, KAKENHI-PROJECT-16H05152, KAKENHI-PROJECT-17H01563
  • [Journal Article] The muscular dystrophy gene TMEM5encodes a ribitol β1-4 Xylosyltransferase required for the functional glycosylation of dystroglycan.2016

    • Author(s)
      Manya, H., Yamaguchi, Y., Kanagawa, M., Kobayashi, K., Tajiri, M., Akasaka-Manya, K., Kawakami, H., Mizuno, M., Wada, Y., Toda, T., and Endo, T.
    • Journal Title

      J. Biol. Chem

      Volume: 291 Issue: 47 Pages: 24618-24627

    • DOI

      10.1074/jbc.m116.751917

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04352, KAKENHI-PROJECT-25460054, KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-16H04758, KAKENHI-PROJECT-16H05353
  • [Journal Article] Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of α-dystroglycan.2016

    • Author(s)
      Kuwabara N, Manya H, Yamada T, Tateno H, Kanagawa M, Kobayashi K, Akasaka-Manya K, Hirose Y, Mizuno M, Ikeguchi M, Toda T, Hirabayashi J, Senda T, Endo T, Kato R.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 113 Issue: 33 Pages: 9280-9285

    • DOI

      10.1073/pnas.1525545113

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-15H04352, KAKENHI-PROJECT-16H05071, KAKENHI-PROJECT-16K18522, KAKENHI-PROJECT-16K07284, KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-16H05353
  • [Journal Article] Identification of a post-translational modification with ribitol-phosphate and its defect in muscular dystrophy2016

    • Author(s)
      Kanagawa M, Kobayashi K, Tajiri M, Manya H, Kuga A, Yamaguchi Y, Akasaka-Manya K, Furukawa J, Mizuno M, Kawakami H, Shinohara Y, Wada Y, Endo T, Toda T.
    • Journal Title

      Cell Reports

      Volume: 14 Issue: 9 Pages: 2209-2223

    • DOI

      10.1016/j.celrep.2016.02.017

    • NAID

      120005728438

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-26110712, KAKENHI-PUBLICLY-26110727, KAKENHI-PROJECT-15H04352, KAKENHI-PROJECT-26670499, KAKENHI-PROJECT-25293016, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-25460054, KAKENHI-PROJECT-16H05353
  • [Journal Article] Fukutin is prerequisite to ameliorate muscular dystrophic phenotype by myofiber-selective LARGE expression.2015

    • Author(s)
      Ohtsuka Y, Kanagawa M, Yu CC, Ito C, Chiyo T, Kobayashi K, Okada T, Takeda S’I, Toda T.
    • Journal Title

      Sci Rep

      Volume: 5 Issue: 1 Pages: 8316-8316

    • DOI

      10.1038/srep08316

    • NAID

      120005600773

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12F02422, KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-24500472, KAKENHI-PROJECT-24687017, KAKENHI-PUBLICLY-26110712, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-26670499, KAKENHI-PROJECT-26293328
  • [Journal Article] TRPV2 is critical for the maintenance of cardiac structure and function in mice.2014

    • Author(s)
      Katanosaka Y, Iwasaki K, Ujihara Y, Takatsu S, Nishitsuji K, Kanagawa M, Sudo A, Toda T, Katanosaka K, Mohri S, Naruse K.
    • Journal Title

      Nat Comm

      Volume: 5 Issue: 1 Pages: 3932-3932

    • DOI

      10.1038/ncomms4932

    • NAID

      120005690060

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-24590725, KAKENHI-PROJECT-24687017, KAKENHI-PROJECT-25350544, KAKENHI-PUBLICLY-26110712, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-26282122, KAKENHI-PROJECT-26282127, KAKENHI-PROJECT-26560211, KAKENHI-PROJECT-26220203
  • [Journal Article] Overexpression of LARGE suppresses muscle regeneration via down-regulation of insulin like growth factor 1 and aggravates muscular dystrophy in mice.2014

    • Author(s)
      Saito F, Kanagawa M, Ikeda M, Hagiwara H, Masaki T, Ohkuma H, Katanosaka Y, Shimizu T, Sonno M, Toda T, Matsumura K.
    • Journal Title

      Hum Mol Genet.

      Volume: 23 Pages: 4543-4558

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26282122
  • [Journal Article] Contribution of dysferlin deficiency to skeletal muscle pathology in asymptomatic and severe dystroglycanopathy models: generation of a new model for fukuyama congenital muscular dystrophy.2014

    • Author(s)
      Kanagawa M, Lu Z, Ito C, Matsuda C, Miyake K, Toda T.
    • Journal Title

      Plos ONE

      Volume: 9 Issue: 9 Pages: e106721-e106721

    • DOI

      10.1371/journal.pone.0106721

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-22390374, KAKENHI-PROJECT-24687017, KAKENHI-PUBLICLY-26110712, KAKENHI-PROJECT-26253057
  • [Journal Article] 福山型筋ジストロフィー 遺伝子・病態の解明、分子標的治療を目指して2013

    • Author(s)
      戸田 達史, 谷口 真理子(池田), 金川 基, 小林 千浩
    • Journal Title

      生化学

      Volume: 85 Pages: 253-260

    • NAID

      10031169565

    • Data Source
      KAKENHI-PROJECT-23249049
  • [Journal Article] YY1 binds to α-synuclein 3'-flanking region SNP and stimulates antisense noncoding RNA expression.2013

    • Author(s)
      Mizuta I, Takafuji K, Ando Y, Satake W, Kanagawa M, Kobayashi K, Nagamori S, Shinohara T, Ito C, Yamamoto M, Hattori N, Murata M, Kanai Y, Murayama S, Nakagawa M, Toda T.
    • Journal Title

      J Hum Genet

      Volume: 58 Issue: 11 Pages: 711-719

    • DOI

      10.1038/jhg.2013.90

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-23249049, KAKENHI-PUBLICLY-24110508, KAKENHI-PROJECT-24591198, KAKENHI-PUBLICLY-25110720, KAKENHI-PROJECT-25670420, KAKENHI-PROJECT-25713015
  • [Journal Article] Impaired viability of muscle precursor cells in muscular dystrophy with glycosylation defects and amelioration. of its severe phenotype by limited gene expression.2013

    • Author(s)
      Kanagawa M, et. al.
    • Journal Title

      Hum Mol Genet

      Volume: 22 Issue: 15 Pages: 3003-3015

    • DOI

      10.1093/hmg/ddt157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12F02422, KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-23249049, KAKENHI-PROJECT-24590497, KAKENHI-PROJECT-24659265, KAKENHI-PROJECT-24687017, KAKENHI-PROJECT-25702044
  • [Journal Article] GTDC2 modifies O-mannosylated α-dystroglycan in the endoplasmic reticulum to generate N-acetyl-glucosamine epitopes reactive with CTD110.6 antibody.2013

    • Author(s)
      Ogawa M, Nakamura N, Nakayama Y, Kurosaka A, Manya H, Kanagawa M, Endo T, Furukawa K, Okajim T
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 440 Issue: 1 Pages: 88-93

    • DOI

      10.1016/j.bbrc.2013.09.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23110008, KAKENHI-PUBLICLY-24110507, KAKENHI-PUBLICLY-24110508, KAKENHI-PUBLICLY-24110516, KAKENHI-PUBLICLY-24110523, KAKENHI-PROJECT-24687017, KAKENHI-PROJECT-25293016, KAKENHI-PROJECT-25670140
  • [Journal Article] Absence of post-phosphoryl modification in dystroglycanopathy mouse models and wild-type tissues expressing a non-laminin binding form of alpha-dystroglycan2012

    • Author(s)
      Kuga A, Kanagawa M, Sudo A, Chan YM, Tajiri M, Manya H, Kikkawa Y, Nomizu M, Kobayashi K, Endo T, Lu QL, Wada Y, Toda T
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 9560-9567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249049
  • [Journal Article] Pathogenic exon-trapping by SVA retrotransposon and rescue in Fukuyama muscular dystrophy2011

    • Author(s)
      Taniguchi-Ikeda M, Kobayashi K, Kanagawa M, Yu CC, Mori K, Oda T, Kuga A, Kurahashi H, Akman HO, DiMauro S, Kaji R, Yokota T, Takeda S, Toda T
    • Journal Title

      Nature

      Volume: 478 Issue: 7367 Pages: 127-131

    • DOI

      10.1038/nature10456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390101, KAKENHI-PROJECT-21390269, KAKENHI-PROJECT-21689030, KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-22790980, KAKENHI-PUBLICLY-23013019, KAKENHI-PROJECT-23249049, KAKENHI-PROJECT-23659182
  • [Journal Article] 【筋ジストロフィーの分子病態から治療へ】福山型筋ジストロフィー症の成因2011

    • Author(s)
      金川基
    • Journal Title

      生体の科学

      Volume: 62巻2号 Pages: 91-94

    • Data Source
      KAKENHI-PROJECT-23249049
  • [Journal Article] Residual glycosylation of dystroglycan in model mice to Fukuyama-type congenital muscular dystrophy is sufficient to maintain voluntary exercise activity and skeletal muscle regeneration capability.2010

    • Author(s)
      Lu Z, Kanagawa M, Toda T.
    • Journal Title

      Medical Journal Osaka University 53

      Pages: 51-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Journal Article] Post-translational maturation of dystroglycan is necessary for pikachurin binding and ribbon synaptic localization.2010

    • Author(s)
      Motoi Kanagawa
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 31208-31216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Journal Article] Post-translational maturation of dystroglycan is necessary for pikachurin binding and ribbon synaptic localization.2010

    • Author(s)
      Kanagawa M, Omori Y, Sato S, Kobayashi K, Miyagoe-Suzuki Y, Takeda S, Endo T, Furukawa T, Toda T.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 31208-31216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Journal Article] Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy.2009

    • Author(s)
      Kanagawa, M., Nishimoto, A., Chiyonobu, T., Takeda, S., Miyagoe-Suzuki,Y., Wang, F., Fujikake, N., Taniguchi, M., Lu, Z., Tachikawa, M., Nagai, Y., Tashiro, F., Miyazaki, J., Tajima, Y., Takeda, S., Endo, T., Kobayashi, K., Campbell, K.P., Toda, T.
    • Journal Title

      Hum. Mol. Genet. 18

      Pages: 621-631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Journal Article] Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy2009

    • Author(s)
      Motoi Kanagawa
    • Journal Title

      Human Molecular Genetics 18

      Pages: 621-631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Journal Article] Basal lamina strengthens cell membrane integrity via the laminin G domain-binding motif of alpha-dystroglycan.2009

    • Author(s)
      Han R, Kanagawa M, Yoshida-Moriguchi T, Rader EP, Ng RA, Michele DE, Muirhead DE, Kunz S, Moore SA, Iannaccone ST, Miyake K, McNeil PL, Mayer U, Oldstone MB, Faulkner JA, Campbell KP.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 106

      Pages: 12573-12579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Journal Article] Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy.2009

    • Author(s)
      Kanagawa M, Nishimoto A, Chiyonobu T, Takeda S, Miyagoe-SuzukiY, Wang F, Fujikake N, Taniguchi M, Lu Z, Tachikawa M, Nagai Y, Tashiro F, Miyazaki J, Tajima Y, Takeda S, Endo T, Kobayashi K, Campbell KP, Toda T.
    • Journal Title

      Hum.Mol.Genet. 18

      Pages: 621-631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Journal Article] Reduced expression of sarcospan in muscles of Fukuyama congenital muscular dystrophy.2008

    • Author(s)
      Wakayama, Y., Inoue, M., Kojima, H., Yamashita, S., Shibuya, S., Jimi, T., Hara, H., Matsuzaki, Y., Oniki, H., Kanagawa, M., Kobayashi, K., Toda, T.
    • Journal Title

      Histol. Histopathol. 23

      Pages: 1425-1438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Journal Article] Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation.2008

    • Author(s)
      Sato S, Omori Y, Katoh K, Kondo M, Kanagawa M, Miyata K, Funabiki K, Koyasu T, Kajimura N, Miyoshi T, Sawai H, Kobayashi K, Tani A, Toda T, Usukura J, Tano Y, Fujikado T, Furukawa T.
    • Journal Title

      Nat.Neurosci. 11

      Pages: 923-931

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Journal Article] Reduced expression of sarcospan in muscles of Fukuyama congenital muscular dystrophy.2008

    • Author(s)
      Wakayama Y, Inoue M, Kojima H, Yamashita S, Shibuya S, Jimi T, Hara H, Matsuzaki Y, Oniki H, Kanagawa M, Kobayashi K, Toda T.
    • Journal Title

      Histol.Histopathol. 23

      Pages: 1425-1438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Patent] ジストログリカン糖鎖修飾異常に伴う疾患の治療剤及び関連酵素測定法2022

    • Inventor(s)
      戸田達史,小林千浩,金川基,遠藤玉夫,萬谷博,和田芳直,田尻道子
    • Industrial Property Rights Holder
      戸田達史,小林千浩,金川基,遠藤玉夫,萬谷博,和田芳直,田尻道子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Acquisition Date
      2022
    • Data Source
      KAKENHI-PROJECT-20H00526
  • [Patent] 新規CDP-リビトール誘導体2020

    • Inventor(s)
      金川基、徳岡秀紀、戸田達史
    • Industrial Property Rights Holder
      金川基、徳岡秀紀、戸田達史
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20H00526
  • [Patent] 新規CDP-リビトール誘導体2020

    • Inventor(s)
      金川基
    • Industrial Property Rights Holder
      金川基
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PLANNED-17H06421
  • [Patent] 新規CDP-リビトール誘導体2020

    • Inventor(s)
      金川基、徳岡秀紀、戸田達史
    • Industrial Property Rights Holder
      金川基、徳岡秀紀、戸田達史
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-067017
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Patent] 筋ジストロフィー関連心筋症の治療又は予防剤2018

    • Inventor(s)
      片野坂友紀, 成瀬恵治, 氏原嘉洋, 戸田達史, 金川基
    • Industrial Property Rights Holder
      片野坂友紀, 成瀬恵治, 氏原嘉洋, 戸田達史, 金川基
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-044752
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Patent] ジストログリカン糖鎖修飾異常に伴う疾患の治療剤2016

    • Inventor(s)
      戸田 達史、小林 千浩、金川 基、他
    • Industrial Property Rights Holder
      国立大学法人神戸大学、他
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-160390
    • Filing Date
      2016-08-18
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] Ribitol-phosphate modification and muscular dystrophy2023

    • Author(s)
      金川 基
    • Organizer
      第96回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02685
  • [Presentation] Pathogenesis and therapeutic strategy for dystroglycanopathy2023

    • Author(s)
      Motoi Kanagawa
    • Organizer
      1st Symposium on "Skeletal muscle cells in Growth and Disease"
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02685
  • [Presentation] CDP-ribitol supplementation therapy and pathomechanism of dystroglycanopathy-related cardiomyopathy2023

    • Author(s)
      Motoi Kanagawa
    • Organizer
      7th International Workshop for Glycosylation Defects in Muscular Dystrophies
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02685
  • [Presentation] 糖鎖異常型筋ジストロフィーの発症機序にもとづいたCDP-リビトール補充療法の開発2022

    • Author(s)
      金川 基
    • Organizer
      第45回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20H00526
  • [Presentation] 糖鎖異常型筋ジストロフィーの発症機序にもとづいたCDP-リビトール補充療法の開発2022

    • Author(s)
      金川基
    • Organizer
      第45回日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K19509
  • [Presentation] 糖鎖異常型筋ジストロフィーの発症機序にもとづいたCDP-リビトール補充療法の開発2022

    • Author(s)
      金川 基
    • Organizer
      第45回日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02685
  • [Presentation] リビトールリン酸という新規糖鎖ユニットの発見と疾患2022

    • Author(s)
      金川 基
    • Organizer
      第95回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02685
  • [Presentation] リビトールリン酸という新規糖鎖ユニットの発見と疾患2022

    • Author(s)
      金川基
    • Organizer
      第95回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K19509
  • [Presentation] リビトールリン酸という新規糖鎖ユニットの発見と疾患2022

    • Author(s)
      金川 基
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20H00526
  • [Presentation] 骨格筋維持機構としての基底膜―細胞膜連携とその破綻による疾患2021

    • Author(s)
      金川 基
    • Organizer
      第44回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20H00526
  • [Presentation] ジストログリカンが担う基底膜―細胞膜連携の破綻と筋ジストロフィー2020

    • Author(s)
      金川基
    • Organizer
      第93回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] 福山型筋ジストロフィーのモデルマウスを用いた病態解明と治療戦略の開発2020

    • Author(s)
      金川基,戸田達史
    • Organizer
      第38回日本神経治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00526
  • [Presentation] 福山型筋ジストロフィーのモデルマウスを用いた病態解明と治療戦略の開発2020

    • Author(s)
      金川基,戸田達史
    • Organizer
      第38回日本神経治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] ジストログリカン糖鎖異常を原因とする心筋症の病態機序2020

    • Author(s)
      金川基,氏原嘉洋,片野坂友紀
    • Organizer
      第39回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] 福山型筋ジストロフィーのモデルマウスを用いた病態解明と治療戦略の開発2020

    • Author(s)
      金川基,戸田達史
    • Organizer
      第38回日本神経治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06421
  • [Presentation] ジストログリカンが担う基底膜―細胞膜連携の破綻と筋ジストロフィー2020

    • Author(s)
      金川基
    • Organizer
      第93回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-17H06421
  • [Presentation] ジストログリカンの機能発現に必要なリビトールリン酸修飾ゾーンの探索と意義2019

    • Author(s)
      金川基
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] Temporal requirement of dystroglycan glycosylation during brain development and rescue of severe cortical dysplasia via gene delivery in the fetal stage.2019

    • Author(s)
      Kanagawa M, Toda T
    • Organizer
      The 6th International Workshop for Glycosylation Defects in Muscular Dystrophies
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] 新規翻訳後修飾体リビトールリン酸の修飾機序と筋組織における生理的役割2019

    • Author(s)
      金川基
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] 機械負荷に対する防御装置としての糖鎖と機械生物学的な意義2019

    • Author(s)
      金川基
    • Organizer
      第57回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] Pathological analysis of model mice for Fukuyama congenital muscular dystrophy and exploration of therapeutic strategy.2018

    • Author(s)
      Kanagawa M, Fukada SI, Okada T, Takeda SI, Toda T
    • Organizer
      11th Japanese-French Workshop New insights in personalized medicine for neuromuscular diseases: from basic to applied myology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] ジストログリカンから見出された新規リビトールリン酸修飾の分子機構と生理機能2018

    • Author(s)
      金川 基
    • Organizer
      第91回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] ジストログリカンがつくる基底膜ジャンクションと病態2018

    • Author(s)
      金川 基
    • Organizer
      第41回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02616
  • [Presentation] Mechanobiology of Muscle and Sugar Chain2017

    • Author(s)
      Motoi Kanagawa
    • Organizer
      The 3rd International Symposium on Mechanobiology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] 筋ジストロフィー発症に関わる糖鎖構造の解明と修飾酵素の同定2017

    • Author(s)
      金川基
    • Organizer
      生命科学系学会合同年次大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] Mechanobiology of muscle and sugar chain2017

    • Author(s)
      Motoi Kanagawa,
    • Organizer
      The 3rd International Symposium on Mechanobiology
    • Data Source
      KAKENHI-PLANNED-17H06421
  • [Presentation] Identification of a post-translational modification with ribitol-phosphate and its defect in muscular dystrophy: Roles of ISPD, fukutin, and FKRP in α-dystroglycan glycosylation2017

    • Author(s)
      Motoi Kanagawa, Kazuhiro Kobayashi, Michiko Tajiri, Hiroshi Manya, Atsushi Kuga, Yoshiki Yamaguchi, Yoshinao Wada, Tamao Endo, Tatsushi Toda
    • Organizer
      Experimental Biology 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] 筋ジストロフィー発症に関わる糖鎖構造の解明と修飾酵素の同定2017

    • Author(s)
      金川 基
    • Organizer
      生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PLANNED-17H06421
  • [Presentation] Identification of a post-translational modification with ribitol-phosphate and its defect in muscular dystrophy: Roles of ISPD, fukutin, and FKRP in alpha-dystroglycan glycosylation2016

    • Author(s)
      Kanagawa, M., Kobayashi K., Tajiri M., Manya H., Kuga A., Yamaguchi Y., Wada Y., Endo T., Toda T.
    • Organizer
      New Directions in Biology and Disease of Skeletal Muscle Conference
    • Place of Presentation
      オーランド
    • Year and Date
      2016-06-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] 新規糖鎖ユニット“リビトールリン酸”の同定と筋ジストロフィーへの関与2016

    • Author(s)
      金川 基、小林 千浩、田尻 道子、萬谷 博、久我 敦、山口 芳樹、和田 芳直、遠藤 玉夫、戸田 達史
    • Organizer
      第63回日本生化学会近畿支部例会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-31
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] 新型の翻訳後修飾ユニット“リビトールリン酸” と筋ジストロフィー2016

    • Author(s)
      金川 基
    • Organizer
      関西グライコフォーラム
    • Place of Presentation
      大阪
    • Year and Date
      2016-05-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] Pathological roles of abnormal glycosylation of dystroglycan in congenital muscular dystrophy with brain anomaly2016

    • Author(s)
      金川 基
    • Organizer
      The 3rd International Symposium on Glyco-Neuroscience
    • Place of Presentation
      淡路
    • Year and Date
      2016-01-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26110712
  • [Presentation] 新型の翻訳後修飾体「リビトールリン酸」の同定~修飾機序と筋ジストロフィー病態への関与~2016

    • Author(s)
      金川 基、小林 千浩、田尻 道子、萬谷 博、久我 敦、山口 芳樹、和田 芳直、遠藤 玉夫、戸田 達史
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] Pathological roles of abnormal glycosylation of dystroglycan in congenital muscular dystrophy with brain anomaly2016

    • Author(s)
      金川 基
    • Organizer
      The 3rd International Symposium on Glyco-Neuroscience
    • Place of Presentation
      淡路
    • Year and Date
      2016-01-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] 糖転移酵素LARGE活性を応用したジストログリカノパチー治療の検討2015

    • Author(s)
      大塚 喜久、金川 基、千代 智子、小林 千浩、岡田 尚巳、武田 伸一、戸田 達史
    • Organizer
      第34回日本糖質学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-31
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] 糖転移酵素LARGE活性を応用したジストログリカノパチー治療の検討2015

    • Author(s)
      大塚 喜久、金川 基、千代 智子、小林 千浩、岡田 尚巳、武田 伸一、戸田 達史
    • Organizer
      第34回日本糖質学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-31
    • Data Source
      KAKENHI-PUBLICLY-26110712
  • [Presentation] 糖鎖異常型筋ジストロフィーモデルに対する遺伝子治療2015

    • Author(s)
      金川 基、大塚 喜久、小林 千浩、千代 智子、岡田 尚巳、武田 伸一、戸田 達史
    • Organizer
      第1回日本筋学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-08
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] 糖鎖修飾異常型筋ジストロフィーの病態機序と治療戦略2015

    • Author(s)
      金川 基、戸田 達史
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会年会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PUBLICLY-26110712
  • [Presentation] 糖鎖修飾異常型筋ジストロフィーの病態機序と治療戦略2015

    • Author(s)
      金川 基、戸田 達史
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会年会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H04352
  • [Presentation] 糖鎖異常型筋ジストロフィーモデルに対する遺伝子治療2015

    • Author(s)
      金川 基、大塚 喜久、小林 千浩、千代 智子、岡田 尚巳、武田 伸一、戸田 達史
    • Organizer
      第1回日本筋学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-08
    • Data Source
      KAKENHI-PUBLICLY-26110712
  • [Presentation] Pathological roles of abnormal glycosylation of dystroglycan in congenital muscular dystrophy with brain anomaly2014

    • Author(s)
      Kanagawa, M.
    • Organizer
      International Symposium on Glyco-Neuroscience
    • Place of Presentation
      淡路
    • Data Source
      KAKENHI-PUBLICLY-24110508
  • [Presentation] 糖鎖機能と修飾機序の解明にもとづく筋ジストロフィー病態と治療法に関する研究2013

    • Author(s)
      金川 基
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] ジストログリカンのユニークな翻訳後修飾とその破綻による病態2013

    • Author(s)
      金川 基、戸田 達史
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] Impaired viability of muscle precursor cells in muscular dystrophy with glycosylation defects and amelioration of its severe phenotype by limited gene expression2013

    • Author(s)
      Kanagawa, M., Yu, C-C., Ito, C., Fukada, S-I., Chiyo, T., Kobayashia, K., Okada, T., Takeda, S’I. Toda, T.
    • Organizer
      18th International Congress of the World Muscle Society
    • Place of Presentation
      Asilomar, California, USA
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] 福山型筋ジストロフィー及び類縁疾患モデルマウスの中枢神経病態の解析2013

    • Author(s)
      首藤 篤史、 金川 基、 辻 沙織、 伊藤 千代美、 戸田 達史
    • Organizer
      2013年度 包括脳ネットワーク夏のワークショップ
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PUBLICLY-24110508
  • [Presentation] 糖鎖機能解析に基づく筋ジストロフィー病態の解明と治療法の開発2013

    • Author(s)
      金川 基
    • Organizer
      第33回日本糖質学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] Impaired viability of muscle precursor cells in muscular dystrophy with glycosylation defects and amelioration of its severe phenotype by limited gene expression2013

    • Author(s)
      Kanagawa, M., Yu, C-C., Ito, C., Fukada, S-I., Chiyo, T., Kobayashia, K., Okada, T., Takeda, S’I. Toda, T.
    • Organizer
      EMBO Workshop
    • Place of Presentation
      Ascona, Switzerland
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] ジストログリカン糖鎖の機能解析にもとづく神経筋病態の解明と治療法の開発2013

    • Author(s)
      金川基、 戸田達史
    • Organizer
      2013年度 包括脳ネットワーク夏のワークショップ
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PUBLICLY-24110508
  • [Presentation] 2種類のフクチン欠損マウスを用いた福山型筋ジストロフィーの病態解析と遺伝子治療2013

    • Author(s)
      金川 基、游 智傑、伊藤 千代美、深田 宗一朗、千代 智子、小林 千浩、岡田 尚巳、武田 伸一、戸田 達史
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] 福山型筋ジストロフィーモデルマウスにおける筋前駆細胞の機能障害2013

    • Author(s)
      松尾 恵、金川 基、伊藤 千代美、小林 千浩、深田 宗一朗、戸田 達史
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] 福山型筋ジストロフィーの発症機序と治療戦略2013

    • Author(s)
      金川 基、戸田 達史
    • Organizer
      第33回日本糖質学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] Disruption of dystroglycan-pikachurin interaction underlies the molecular pathogenesis of eye abnormalities in dystroglycanopathy2012

    • Author(s)
      金川基
    • Organizer
      2012 New Directions in Biology and Disease of Skeletal Muscle Conference
    • Place of Presentation
      New Orleans (米国)
    • Year and Date
      2012-06-18
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] 糖鎖異常型筋ジストロフィーの発症機序と治療戦略2012

    • Author(s)
      金川基
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2012-12-12
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] ジストログリカンに見出された新規糖鎖修飾体の生理機能と筋ジストロフィー病態への関与2012

    • Author(s)
      金川基
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] ジストログリカンに見出された新規糖鎖修飾による機能制御と病態2012

    • Author(s)
      金川基
    • Organizer
      第31回日本糖質学会年会
    • Place of Presentation
      鹿児島
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] 糖鎖異常型筋ジストロフィーの 発症機序と治療戦略2012

    • Author(s)
      金川 基
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PUBLICLY-24110508
  • [Presentation] ジストログリカンの新規リガンド分子ピカチュリンの結合解析と糖鎖異常型筋ジストロフィー病態への関与2011

    • Author(s)
      金川基
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都国際会館(京都)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-23249049
  • [Presentation] Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy.2010

    • Author(s)
      Kanagawa M
    • Organizer
      25th International Carbohydrate Symposium ICS2010.
    • Place of Presentation
      Makuhari, Japan.
    • Year and Date
      2010-08-03
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy.2010

    • Author(s)
      Kanagawa M
    • Organizer
      New Directions in Biology and Disease of Skeletal Muscle.
    • Place of Presentation
      Ottawa, Canada
    • Year and Date
      2010-05-06
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Molecular basis and physiological roles of dystroglycan glycosylation and its relevance to diseases2010

    • Author(s)
      Motoi Kanagawa
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸国際展示場(兵庫県)(招待講演)
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] レトロトランスポゾン挿入変異をもつ福山型先天性筋ジストロフィーモデルマウスの創出と糖鎖遺伝子治療2010

    • Author(s)
      金川基
    • Organizer
      日本人類遺伝学会第55回大会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Year and Date
      2010-10-29
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] レトロトランスポゾン挿入変異をもつ福山型先天性筋ジストロフィーモデルマウスの創出と糖鎖遺伝子治療2010

    • Author(s)
      金川基
    • Organizer
      日本人類遺伝学会第55回大会
    • Place of Presentation
      さいたま.
    • Year and Date
      2010-10-29
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy2010

    • Author(s)
      Motoi Kanagawa
    • Organizer
      The 25th International Carbohydrate Symposium
    • Place of Presentation
      幕張メッセ(千葉県)
    • Year and Date
      2010-08-03
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Disruption of dystroglycan-pikachurin interaction underlies the molecular pathogenesis of eye abnormalities in dystroglycanopathy2010

    • Author(s)
      Motoi Kanagawa
    • Organizer
      The 15th International Congress of World Muscle Society
    • Place of Presentation
      崇城大学市民ホール(熊本県)
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Post-translational maturation of dystroglycan is necessary for pikachurin binding and ribbon synaptic localization2010

    • Author(s)
      Motoi Kanagawa
    • Organizer
      第28回内藤コンファレンス
    • Place of Presentation
      湘南国際村センター(神奈川県)
    • Year and Date
      2010-07-28
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Molecular basis and physiological roles of dystroglycan glycosylation and its relevance to diseases2010

    • Author(s)
      Kanagawa M
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy2010

    • Author(s)
      Motoi Kanagawa
    • Organizer
      The Ottawa Conference on New Directions in Biology and Disease of Skeletal Muscle
    • Place of Presentation
      オタワ(カナダ)
    • Year and Date
      2010-05-06
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Disruption of dystroglycan-pikachurin interaction underlies the molecular pathogenesis of eye abnormalities in dystroglycanopathy.2010

    • Author(s)
      Kanagawa M
    • Organizer
      15th International Congress of the World Muscle Society.
    • Place of Presentation
      Kumamoto, Japan.
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Disruption of dystroglycan-pikachurin interaction underlies the molecular pathogenesis of eye abnormalities in dystroglycanopathy.2010

    • Author(s)
      Kanagawa M
    • Organizer
      第28回内藤コンファレンス Glycan Expression and Regulation [I] : Functions and Disease mechanisms(糖鎖の発現と制御[I]-機能から病態まで-)
    • Place of Presentation
      葉山
    • Year and Date
      2010-07-28
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Essential role of dystroglycan in the maintenance of cell membrane.2009

    • Author(s)
      Kanagawa M
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy2009

    • Author(s)
      Kanagawa, M., Nishimoto, A., Chiyonobu, T., Takeda, S., Miyagoe-Suzuki, Y., Wang, F., Taniguchi, M., Lu, Z., Tachikawa, M., Tajima, Y., Takeda, S., Endo, T., Kobayashi, K., Campbell, K.P., Toda, T.
    • Organizer
      Clinical and Translational Research on Cancer : Glycomics Applications and The 2^<nd> Seminar on Functional Glycomics for Young Investigators
    • Place of Presentation
      鳥羽
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Presentation] Subcellular localization and POMGnT1-binding of fukutin missense mutants which are involved in the onset of FCMD.2009

    • Author(s)
      Kanagawa M
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] ジストログリカンの糖鎖異常を示すモデルマウスを用いた先天性筋ジストロフィーの病態解析と治療戦略の構築2008

    • Author(s)
      金川基
    • Organizer
      第31回日本分子生物学会年会 第81回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Molecular Pathogenesis and Therapeutic Strategy for Congenital Muscular Dystrophies Caused by Abnormal Giycosylation of Dystroglycan2008

    • Author(s)
      金川基
    • Organizer
      第28回日本糖質学会年会
    • Place of Presentation
      つくば
    • Year and Date
      2008-08-18
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Presentation] Generation of a model mouse for Fukuyama congenital muscular dystrophy carrying a retrotransposal insertion in the 3' UTR in the fukutin gene.2008

    • Author(s)
      Kanagawa M
    • Organizer
      The Third New Directions in Skeletal Muscle Biology Meeting.
    • Place of Presentation
      New Orleans, U.S.A.
    • Year and Date
      2008-04-29
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] ジストログリカンの糖鎖異常を示すモデルマウスを用いた先天性筋ジストロフィーの病態解析と治療戦略の構築2008

    • Author(s)
      金川 基、西本明美、千代延友裕、武田 聖、戸田達史
    • Organizer
      Biochemistry and Molecular Biology 2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Presentation] Generation of a model mouse for Fukuyama congenital muscular dystrophy carrying a retrotransposal insertion in the 3' UTR in the fukutin gene2008

    • Author(s)
      金川基
    • Organizer
      New Direction of Muscle Biology and Disease 2008
    • Place of Presentation
      New Orleans
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Presentation] ジストログリカンの糖鎖異常を伴う先天性筋ジストロフィーの病態と治療戦略2008

    • Author(s)
      金川基
    • Organizer
      第28回日本糖質科学会
    • Place of Presentation
      つくば
    • Year and Date
      2008-08-18
    • Data Source
      KAKENHI-PROJECT-21790318
  • [Presentation] Generation of a model mouse for Fukuyama congenital muscular dystrophy carrying a retrotransposal insertion in the 3' UTR in the fukutin gene2008

    • Author(s)
      Kanagawa, M., Nishimoto, A., Chiyonobu, T., Takeda, S., Toda, T.
    • Organizer
      The Third New Directions in Skeletal Muscle Biology Meeting
    • Place of Presentation
      New Orleans
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Presentation] Molecular Pathogenesis and Therapeutic Strategy for Congenital Muscular Dystrophies Caused by Abnormal Glycosylation of Dystroglycan2008

    • Author(s)
      Kanagawa, M., Nishimoto, A., Chiyonobu T., Toda, T.
    • Organizer
      28th Japanese Carbohydrate Symposium
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Presentation] ジストログリカンの糖鎖異常を示すモデルマウスを用いた先天性筋ジストロフィーの病態解析と治療戦略の構築2008

    • Author(s)
      金川基
    • Organizer
      日本分子生物学会年会日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Presentation] Molecular interaction between fukutin and POMGnTl in the glycosylationpathway of alpha-dystroglycan2007

    • Author(s)
      金川 基
    • Organizer
      第27回札幌がんセミナー
    • Place of Presentation
      札幌
    • Year and Date
      2007-07-13
    • Data Source
      KAKENHI-PROJECT-19790232
  • [Presentation] Impaired viability of muscle precursor cells in muscular dystrophy with glycosylation defects and amelioration of its severe phenotype by limited gene expression

    • Author(s)
      Kanagawa, M., Yu, C-C., Ito, C., Fukada, S-I., Chiyo, T., Kobayashia, K., Okada, T., Takeda, S’I. Toda, T.
    • Organizer
      13th International Congress on Neuromuscular Diseases
    • Place of Presentation
      Nice
    • Year and Date
      2014-07-05 – 2014-07-10
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] Pathophysiological roles for dystroglycan glycosylation in skeletal muscle and gene therapy challenge using glycosylation-deficient muscular dystrophy models

    • Author(s)
      Kanagawa, M., Yu, C-C., Fukada, S-I., Ohtsuka, Y., Ito, C., Chiyo, T., Okada,T., Takeda, S’I., Toda, T.
    • Organizer
      Society for Glycobiology (SFG) & Japanese Society of carbohydrate Research (JSCR) 2014 Joint Annual Meeting
    • Place of Presentation
      Honolulu
    • Year and Date
      2014-11-16 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] 糖鎖異常型筋ジストロフィーに対する遺伝子治療

    • Author(s)
      金川 基、大塚 喜久、游 智傑、伊藤 千代美、千代 智子、岡田 尚巳、武田 伸一、戸田 達史
    • Organizer
      第33回日本糖質学会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-08-10 – 2014-08-12
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] Pathological analysis of central nervous system in fukutin-deficient mouse models for Fukuyama congenital muscular dystrophy

    • Author(s)
      Kanagawa, M., Sudo, A., Ito, C., Toda, T.
    • Organizer
      Society for Glycobiology (SFG) & Japanese Society of carbohydrate Research (JSCR) 2014 Joint Annual Meeting
    • Place of Presentation
      Honolulu
    • Year and Date
      2014-11-16 – 2014-11-19
    • Data Source
      KAKENHI-PUBLICLY-26110712
  • [Presentation] 糖鎖異常型筋ジストロフィーに対する遺伝子治療

    • Author(s)
      金川 基、大塚 喜久、游 智傑、伊藤 千代美、千代 智子、岡田 尚巳、武田 伸一、戸田 達史
    • Organizer
      第33回日本糖質学会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-08-10 – 2014-08-12
    • Data Source
      KAKENHI-PUBLICLY-26110712
  • [Presentation] Impaired viability of muscle precursor cells in muscular dystrophy with glycosylation defects and amelioration of its severe phenotype by limited gene expression

    • Author(s)
      Kanagawa, M., Yu, C-C., Ito, C., Fukada, S-I., Chiyo, T., Kobayashia, K., Okada, T., Takeda, S’I. Toda, T.
    • Organizer
      6th New Directions in Biology and Disease of Skeletal Muscle Conference
    • Place of Presentation
      Chicago
    • Year and Date
      2014-06-29 – 2014-07-02
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] 糖鎖異常型筋ジストロフィーの病態と治療

    • Author(s)
      金川 基、戸田 達史
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24687017
  • [Presentation] 糖鎖異常型筋ジストロフィーの病態と治療

    • Author(s)
      金川 基、戸田 達史
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PUBLICLY-26110712
  • []

  • 1.  Katanosaka Yuki (60432639)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 2 results
  • 2.  Katanosaka Kimiaki (50335006)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 3.  TATSUSHI Toda (30262025)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 4.  NAGAMORI Shushi (90467572)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  MIYAKE Katsuya (30219745)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  KOBAYASHI Kazuhiro (90324780)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 7.  EGAMI Youhei (80432780)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  MATSUDA Chie (50344099)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TANAKA Toru (60217049)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  FUKAI Naomi (60134681)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  ARAKI Shinichi (10202748)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  Iwanami Jun (90624792)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  成瀬 恵治 (40252233)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  毛利 聡 (00294413)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  中村 一文 (10335630)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  氏原 嘉洋 (80610021)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  山口 芳樹 (90323451)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 18.  萬谷 博 (20321870)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 19.  YOSHIYAMA Masahiro (10201071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  IKEDA Mariko (00410738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  Goto Satoshi (60280575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  石川 裕之 (00398819)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  田村 純一 (30221401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  TANIGUCHI Mariko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  SATAKE Wataru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  NAGATA Yosuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  IMAE Rieko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 28.  ISHIURA Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  YAGI Hirokazu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  SAKAGUCHI Hirofumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  SAITO Taku
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  倉橋 浩樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  丸山 敬
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  野水 基義
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  早川 英規
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  遠藤 玉夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  饗場 篤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  吉川 大和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  清水 潤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  上山 健彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  森 大典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  古川 鋼一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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