Manya Hiroshi 萬谷博

… Alternative Names

MANYA Hiroshi 萬谷博

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Researcher Number	20321870
Other IDs
External Links
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長
Affiliation (based on the past Project Information) *help	2023 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 2013 – 2022: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究副部長 2017: 東京都健康長寿医療センター研究所, 研究副部長 2012: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 主任研究員 2008: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 研究員 … More 2008: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 研究員 2007: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 研究員 2005 – 2006: (財)東京都高齢者研究・福祉振興財団, 東京都老人総合研究所, 研究員 2004: 財団法人東京都高齢者研究, 福祉振興財団・東京都老人総合研究所(糖蛋白質研究グループ), 研究員 2002 – 2003: (財)東京都高齢者研究・福祉振興財団, 東京都老人総合研究所・糖蛋白質研究グループ, 研究員 2001: (財)東京都老人総合研究所, 糖鎖生物学部門, 研究員 2000 – 2001: 財団法人東京都老人総合研究所, 糖鎖生物学部門, 研究員 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological Sciences / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy Except Principal Investigator Basic Section 48040:Medical biochemistry-related / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 52:General internal medicine and related fields / Structural biochemistry / Biological pharmacy
Keywords	Principal Investigator 糖鎖 / 脳神経疾患 / 老化 / O-マンノース型糖鎖 / 筋疾患 / 神経疾患 / klotho / アルツハイマー病 / 糖転移酵素 / アミロイド前駆体タンパク質 … More / calpain / 生化学 / 糖 / プロテオグリカン / カルパイン / アスパラギン結合型糖鎖 / アミロイドβ / アミロイド前駆体蛋白質 / 家族性アルツハイマー病 … More Except Principal Investigator 糖鎖 / ジストログリカン / 筋ジストロフィー / 分子ネットワーク / シアル酸 / 糖鎖ネットワーク / グライコミクス / ネットワーク / 老化 / リビトール / バイオマーカー / 遺伝環境リスク / 抗核抗体 / PlexinD1 / NF155 / 慢性炎症性脱髄性多発神経根炎 / 神経内科疾患 / 神経障害性疼痛 / ノド抗体 / 自己抗体 / アトピー性脊髄炎 / アトピー / 環境因子 / 遺伝子 / 自己免疫 / 慢性炎症性脱髄性多発神経炎 / 多発性硬化症 / 脱髄疾患 / 神経免疫疾患 / フクチン / リビトールリン酸 / 疾患モデル / POMT2 / POMT1 / 結晶構造解析 / 膜タンパク質 / Differentiation / Galectin / Lectin / Carbohydrate / Tvrosine-phosphorylation / Astrocvte / 蛋白質子ロシン脱リン酸化 / 細胞表面糖鎖 / 老齢脳 / 蛋白質チロシン脱リン酸化 / 分化誘導因子 / レクチン / アストロサイト Less

Molecular basis and physiological significance of O-mannosyl glycans in mammalsPrincipal Investigator
- Principal Investigator
  
  萬谷博
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
包括的組織グライコームによる糖鎖分子ネットワークの構築と老化の客観的評価
- Principal Investigator
  
  古川潤一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagoya University
Elucidation of the molecular basis of novel ribitol phosphate modifications and their application to the development of treatments for muscular dystrophy
- Principal Investigator
  
  Kanagawa Motoi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Ehime University
Elucidation of autoimmune mechanisms and developement of novel therapy for demyelinating diseases based on genetic and envrionmental risk factors and disease-specific anti-neural antibodies
- Principal Investigator
  
  Kira Jun-ichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  International University of Health and Welfare
  Kyushu University
Understanding of the mechanism of ribitol-phosphate modification and application of its physiological function to therapy
- Principal Investigator
  
  Kanagawa Motoi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Ehime University
  Kobe University
Structural diversity and biosynthetic mechanisms of O-mannosyl glycans in mammalsPrincipal Investigator
- Principal Investigator
  
  Manya Hiroshi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Crystallography of membrane protein complex by S-SAD method
- Principal Investigator
  
  KATO Ryuichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  High Energy Accelerator Research Organization
脳発生過程におけるO-マンノース型糖鎖の機能解析Principal Investigator
- Principal Investigator
  
  萬谷博
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Role of glycosylation in processing of APPPrincipal Investigator
- Principal Investigator
  
  Manya Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
脳発生過程におけるＯーマンノース型糖鎖の機能解析Principal Investigator
- Principal Investigator
  
  萬谷博
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Study of abnormal activation of calpain by klotho protein deficiencyPrincipal Investigator
- Principal Investigator
  
  MANYA Hiroshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Klotho蛋白質によるカルパインの活性制御機構の解析Principal Investigator
- Principal Investigator
  
  萬谷博
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
アミロイド前駆体蛋白質糖鎖変化の老人斑形成における意義Principal Investigator
- Principal Investigator
  
  萬谷博
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Elucidation of function of astrocytes appearedin aded brain and its inducing factor
- Principal Investigator
  
  ENDO Tamao
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Gerontology

[Book] Sugar chains2015
- Author(s)
  Manya, H., Endo, T.
- Total Pages
  288
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-26110727
[Book] Sugar chains2015
- Author(s)
  Manya, H., Endo, T.
- Total Pages
  288
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26460090
[Book] Handbook of Glycosyl transferases and related genes.2014
- Author(s)
  Manya, H., Endo, T.
- Total Pages
  670
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-26110727
[Book] Handbook of Glycosyl transferases and related genes. (POMGNT1)2014
- Author(s)
  Manya, H., Endo, T.
- Total Pages
  6
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-24110523
[Book] Handbook of Glycosyl transferases and related genes2014
- Author(s)
  Manya, H., Endo, T.
- Total Pages
  670
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26460090
[Book] Handbook of Glycosyl transferases and related genes. (POMT1,2)2014
- Author(s)
  Manya, H., Endo, T.
- Total Pages
  7
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-24110523
[Book] Klotho マウス. 老化・老年病研究のための動物実験ガイドブック(日本基礎老化学会編)2008
- Author(s)
  萬谷博
- Publisher
  アドスリー
- Data Source
  KAKENHI-PROJECT-18790079
[Journal Article] Changes in the amount of nucleotide sugars in aged mouse tissues2024
- Author(s)
  Imae Rieko、Manya Hiroshi、Tsumoto Hiroki、Umezawa Keitaro、Miura Yuri、Endo Tamao
- Journal Title
  
  Glycobiology
  
  Volume: 34 Issue: 6
- DOI
  10.1093/glycob/cwae032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-23K27328
[Journal Article] Endogenous reductase activities for the generation of ribitol-phosphate, a CDP-ribitol precursor, in mammals2023
- Author(s)
  Hoshino Shunsuke、Manya Hiroshi、Imae Rieko、Kobayashi Kazuhiro、Kanagawa Motoi、Endo Tamao
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 175 Issue: 4 Pages: 418-425
- DOI
  10.1093/jb/mvad115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06110, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-21H02685, KAKENHI-PROJECT-23K24244, KAKENHI-PROJECT-23K27328
[Journal Article] CDP-ribitol prodrug treatment ameliorates ISPD-deficient muscular dystrophy mouse model2022
- Author(s)
  Tokuoka Hideki、Imae Rieko、Nakashima Hitomi、Manya Hiroshi、Masuda Chiaki、Hoshino Shunsuke、Kobayashi Kazuhiro、Lefeber Dirk J.、Matsumoto Riki、Okada Takashi、Endo Tamao、Kanagawa Motoi、Toda Tatsushi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1847-1847
- DOI
  10.1038/s41467-022-29473-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-22K19509, KAKENHI-PROJECT-20H00526, KAKENHI-PROJECT-21H02685, KAKENHI-PROJECT-19K07058, KAKENHI-WRAPUP-22H04899, KAKENHI-PROJECT-23K20328, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-23K24244
[Journal Article] Toolbox Accelerating Glycomics (TAG): Improving Large-Scale Serum Glycomics and Refinement to Identify SALSA-Modified and Rare Glycans2022
- Author(s)
  Miura Nobuaki、Hanamatsu Hisatoshi、Yokota Ikuko、Akasaka-Manya Keiko、Manya Hiroshi、Endo Tamao、Shinohara Yasuro、Furukawa Jun-ichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 21 Pages: 13097-13097
- DOI
  10.3390/ijms232113097
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K12124, KAKENHI-PROJECT-18H02565, KAKENHI-PROJECT-23K24759, KAKENHI-PROJECT-19H05648
[Journal Article] PCYT2 synthesizes CDP-glycerol in mammals and reduced PCYT2 enhances the expression of functionally glycosylated α-dystroglycan2021
- Author(s)
  Imae Rieko、Manya Hiroshi、Tsumoto Hiroki、Miura Yuri、Endo Tamao
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 170 Issue: 2 Pages: 183-194
- DOI
  10.1093/jb/mvab069
- NAID
  40022723391
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-19K07058, KAKENHI-PROJECT-19H05648
[Journal Article] The structure of POMGNT2 provides new insights into the mechanism to determine the functional O ‐mannosylation site on α‐dystroglycan2021
- Author(s)
 Imae Rieko、Kuwabara Naoyuki、Manya Hiroshi、Tanaka Tomohiro、Tsuyuguchi Masato、Mizuno Mamoru、Endo Tamao、Kato Ryuichi
- Journal Title
 
 Genes to Cells
 
 Volume: 26 Issue: 7 Pages: 485-494
- DOI
 10.1111/gtc.12853
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-19K07058, KAKENHI-PROJECT-19H05648
[Journal Article] Biosynthetic Mechanisms of a Unique Ribitol Phosphate-containing Glycan by FKRP, a Ribitol Phosphate Transferase2020
- Author(s)
  Imae R, Kuwabara N, Manya H, Kato R, Endo T
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 32 Issue: 190 Pages: E195-E200
- DOI
  10.4052/tigg.2008.1E
- NAID
  130007942390
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2020-11-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07058, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-19H05648
[Journal Article] FAM3B/PANDER-Like Carbohydrate-Binding Domain in a Glycosyltransferase, POMGNT12020
- Author(s)
  Manya Hiroshi、Kuwabara Naoyuki、Kato Ryuichi、Endo Tamao
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2132 Pages: 609-619
- DOI
  10.1007/978-1-0716-0430-4_52
- ISBN
  9781071604298, 9781071604304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-19H05648
[Journal Article] Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy.2020
- Author(s)
  Kuwabara N, Imae R, Manya H, Tanaka T, Mizuno M, Tsumoto H, Kanagawa M, Kobayashi K, Toda T, Senda T, Endo T, Kato R.
- Journal Title
  
  Nat Commun.
  
  Volume: 11 Issue: 1 Pages: 303-303
- DOI
  10.1038/s41467-019-14220-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07058, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-17H06264
[Journal Article] Lactone-Driven Ester-to-Amide Derivatization for Sialic Acid Linkage-Specific Alkylamidation2020
- Author(s)
  Jun-Ichi Furukawa 1, Hisatoshi Hanamatsu 2, Takashi Nishikaze 3, Hiroshi Manya 4, Nobuaki Miura 5, Hirokazu Yagi 6, Ikuko Yokota 1, Keiko Akasaka-Manya 4, Tamao Endo 4, Motoi Kanagawa 7 8, Norimasa Iwasaki 1, Koichi Tanaka 3
- Journal Title
  
  Anal Chem .
  
  Volume: 3 Issue: 21 Pages: 14383-14392
- DOI
  10.1021/acs.analchem.0c02209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08443, KAKENHI-PROJECT-19K07883, KAKENHI-PROJECT-19K15597, KAKENHI-PROJECT-18H02616, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-19H05648
[Journal Article] Mechanisms of O-Mannosyl Glycan Biosynthesis in Mammals2019
- Author(s)
 Manya Hiroshi
- Journal Title
 
 Trends in Glycoscience and Glycotechnology
 
 Volume: 31 Issue: 181 Pages: SE63-SE64
- DOI
 10.4052/tigg.1930.2SE
- NAID
 130007683661
- ISSN
 0915-7352, 1883-2113
- Year and Date
 2019-07-25
- Language
 English
- Open Access
- Data Source
 KAKENHI-PROJECT-17H03987
[Journal Article] CDP-glycerol inhibits the synthesis of the functionalO-mannosyl glycan of α-dystroglycan2018
- Author(s)
  Imae Rieko、Manya Hiroshi、Tsumoto Hiroki、Osumi Kenji、Tanaka Tomohiro、Mizuno Mamoru、Kanagawa Motoi、Kobayashi Kazuhiro、Toda Tatsushi、Endo Tamao
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 31 Pages: 12186-12198
- DOI
  10.1074/jbc.ra118.003197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-16K20996
[Journal Article] Cell endogenous activities of fukutin and FKRP coexist with the ribitol xylosyltransferase, TMEM5.2018
- Author(s)
  Nishihara, R., Kobayashi, K., Imae, R., Tsumoto, H., Manya, H., Mizuno, M., Kanagawa, M., Endo, T., and Toda, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 497 Issue: 4 Pages: 1025-1030
- DOI
  10.1016/j.bbrc.2018.02.162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-16K20996, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-15H04352, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H03987
[Journal Article] Glycosylation with ribitol-phosphate in mammals: New insights into the O -mannosyl glycan.2017
- Author(s)
  Manya, H., and Endo, T.
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1861 Issue: 10 Pages: 2462-2472
- DOI
  10.1016/j.bbagen.2017.06.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-17H03987
[Journal Article] Identification of ribitol-phosphate in mammalian O-mannosyl glycan and its biosynthetic mechanisms2017
- Author(s)
  萬谷博、遠藤玉夫
- Journal Title
  
  生化学
  
  Volume: 89 Issue: 5 Pages: 605-612
- DOI
  10.14952/SEIKAGAKU.2017.890605
- ISSN
  0037-1017
- Year and Date
  2017-10-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17H03987
[Journal Article] Experimental phase determination with selenomethionine or mercury-derivatization in serial femtosecond crystallography.2017
- Author(s)
  Yamashita, K., et al.
- Journal Title
  
  IUCrJ
  
  Volume: 4 Issue: 5 Pages: 639-647
- DOI
  10.1107/s2052252517008557
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-16H02282, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-15K14468, KAKENHI-PROJECT-15K18487
[Journal Article] Mechanism for the Deficiency in Post-Phosphoryl Modification of α-Dystroglycan Observed in POMGnT1-Caused Muscular Dystrophy2017
- Author(s)
  桑原直之, 加藤龍一, 萬谷博, 遠藤玉夫
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 59 Issue: 2-3 Pages: 114-120
- DOI
  10.5940/jcrsj.59.114
- NAID
  130006767785
- ISSN
  0369-4585, 1884-5576
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07284, KAKENHI-PROJECT-17H03987
[Journal Article] 3D structural analysis of protein O-mannosyl kinase, POMK, a causative gene product of dystroglycanopathy2017
- Author(s)
  M.Nagae, S.K.Mishra, M.Neyazaki, R.Oi, A.Ikeda, N.Matsugaki, S.Akashi, H.Manya, M.Mizuno, H.Yagi, K.Kato, T.Senda, T.Endo, T.Nogi, and Y.Yamaguchi
- Journal Title
  
  Genes Cells
  
  Volume: - Issue: 4 Pages: 348-359
- DOI
  10.1111/gtc.12480
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-26291016, KAKENHI-PROJECT-25460054, KAKENHI-PROJECT-15K18496, KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-15K07935, KAKENHI-PROJECT-26505009, KAKENHI-PROJECT-16H04758
[Journal Article] Excess APP O-glycosylation by GalNAc-T6 decreases Aβ production.2017
- Author(s)
  Keiko Akasaka-Manya, Masaki Kawamura, Hiroki Tsumoto, Yuko Saitoh, Yuriko Tachida, Shinobu Kitazume, Hiroyuki Hatsuta, Yuri Miura, Shin-ichi Hisanaga, Shigeo Murayama, Yasuhiro Hashimoto, Hiroshi Manya, Tamao Endo
- Journal Title
  
  J. Biochem.
  
  Volume: 161 Issue: 1 Pages: 99-111
- DOI
  10.1093/jb/mvw056
- NAID
  40021091544
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460090, KAKENHI-PROJECT-26460394, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16H06277
[Journal Article] Tatsushi Toda and Tamao Endo win 107th Japan Academy Prize2017
- Author(s)
  Kanagawa Motoi、Manya Hiroshi
- Journal Title
  
  Glycobiology
  
  Volume: 27 Issue: 7 Pages: 599-600
- DOI
  10.1093/glycob/cwx040
- Open Access
- Data Source
  KAKENHI-PROJECT-17H03987
[Journal Article] Analysis of phenotype, enzyme activity, and genotype of Chinese patients with POMT1 mutation2016
- Author(s)
  Haipo Yang, Hiroshi Manya, Kazuhiro Kobayashi, HUI JIAO, Xiaona Fu, Jiangxi Xiao, Xiaoqing Li, Jingmin wang, Yuwu Jiang, TATSUSHI TODA, Tamao Endo, Xiru Wu,Hui Xiong,
- Journal Title
  
  J. Hum. Genet
  
  Volume: 印刷中 Issue: 8 Pages: 753-759
- DOI
  10.1038/jhg.2016.42
- NAID
  40020923851
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110727, KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-16H05353
[Journal Article] Mutations in POMGNT1 cause non-syndromic retinitis pigmentosa.2016
- Author(s)
  Mingchu Xu, Takeyuki Yamada, Zixi Sun, Aiden Eblimit, Irma Lopez, Feng Wang, Hiroshi Manya, Shan Xu, Li Zhao, Yumei Li, Adva Kimchi, Dror Sharon, Ruifang Sui, Tamao Endo, Robert K. Koenekoop, Rui Chen
- Journal Title
  
  Hum. Mol. Genet.
  
  Volume: 25 Issue: 8 Pages: 1479-1488
- DOI
  10.1093/hmg/ddw022
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110727, KAKENHI-PROJECT-26860682, KAKENHI-PROJECT-25293016, KAKENHI-PROJECT-16K08262
[Journal Article] Identification of a post-translational modification with ribitol-phosphate and its defect in muscular dystrophy2016
- Author(s)
  Kanagawa M, Kobayashi K, Tajiri M, Manya H, Kuga A, Yamaguchi Y, Akasaka-Manya K, Furukawa J, Mizuno M, Kawakami H, Shinohara Y, Wada Y, Endo T, Toda T.
- Journal Title
  
  Cell Reports
  
  Volume: 14 Issue: 9 Pages: 2209-2223
- DOI
  10.1016/j.celrep.2016.02.017
- NAID
  120005728438
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26110712, KAKENHI-PUBLICLY-26110727, KAKENHI-PROJECT-15H04352, KAKENHI-PROJECT-26670499, KAKENHI-PROJECT-25293016, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-25460054, KAKENHI-PROJECT-16H05353
[Journal Article] POMGNT1 Is Glycosylated by Mucin-Type O-Glycans2015
- Author(s)
 Xin X, Akasaka-Manya K, Manya H, Furukawa J, Kuwahara N, Okada K, Tsumoto H, Higashi N, Kato R, Shinohara Y, Irimura T, Endo T.
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 38 Issue: 9 Pages: 1389-1394
- DOI
 10.1248/bpb.b15-00415
- NAID
 130005096979
- ISSN
 0918-6158, 1347-5215
- Language
 English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-25460165, KAKENHI-PROJECT-26670023, KAKENHI-PUBLICLY-26110727, KAKENHI-PROJECT-26840029, KAKENHI-PROJECT-25293011, KAKENHI-PROJECT-25293016
[Journal Article] Major glycan structure underlying expression of the Lewis X epitope in the developing brain is O-mannose-linked glycans on phosphacan/RPTPβ2015
- Author(s)
  Shohei Yaji, Hiroshi Manya, Naoki Nakagawa, Hiromu Take matsu, Tamao Endo, Reiji Kannagi, Toru Yoshihara, Masahide Asano, Shogo Oka
- Journal Title
  
  Glycobiology
  
  Volume: 25 Issue: 4 Pages: 376-385
- DOI
  10.1093/glycob/cwu118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J02038, KAKENHI-PLANNED-23110006, KAKENHI-PROJECT-24590078, KAKENHI-PROJECT-25293016, KAKENHI-PUBLICLY-26110727, KAKENHI-PROJECT-26291021, KAKENHI-PROJECT-26460090, KAKENHI-PROJECT-15K08288
[Journal Article] Human ISPD is a cytidyltransferase required for dystroglycan O-mannosylation.2015
- Author(s)
  Moniek Riemersma, D. Sean Froese, Walinka van Tol, Udo F. Engelke, Jolanta Kopec, Monique van Scherpenzeel, Angel Ashikov, Tobias Krojer4, Frank von Delft, Marco Tessari, Anna Buczkowska, Ewa Swiezewska, Lucas T. Jae, Thijn R. Brummelkamp, Hiroshi Manya, Tamao Endo, Hans van Bokhoven, Wyatt W. Yue, Dirk J. Lefeber
- Journal Title
  
  Chem. Biol.
  
  Volume: 22 Issue: 12 Pages: 1643-1652
- DOI
  10.1016/j.chembiol.2015.10.014
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110727, KAKENHI-PROJECT-25293016
[Journal Article] An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer’s disease2015
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Reiko Fujinawa, Takashi Saito, Nobuhisa Iwata, Takaomi C. Saido, Miyako Nakano, Yoshiki Yamaguchi, Yasuhiro Hashimoto
- Journal Title
  
  EMBO Mol. Med.
  
  Volume: 7(2) Issue: 2 Pages: 175-89
- DOI
  10.15252/emmm.201404438
- NAID
  120006799362
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24110511, KAKENHI-PROJECT-24700371, KAKENHI-PROJECT-25293016, KAKENHI-PROJECT-25460054, KAKENHI-PUBLICLY-26110727, KAKENHI-PUBLICLY-26117522, KAKENHI-PROJECT-26460090, KAKENHI-PROJECT-26460394, KAKENHI-PROJECT-25430122
[Journal Article] α-Klotho mice demonstrate increased expression of the non-sulfated N-glycan form of the HNK-1 glyco-epitope in kidney tissue.2014
- Author(s)
  K. Akasaka-Manya, H. Manya, Y. Kizuka, S. Oka and T. Endo
- Journal Title
  
  J. Biochem.
  
  Volume: 156 Issue: 2 Pages: 107-113
- DOI
  10.1093/jb/mvu024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23110006, KAKENHI-PROJECT-25293016, KAKENHI-PUBLICLY-26110727, KAKENHI-PROJECT-26291021
[Journal Article] Molecular characterization of protein O-linked mannose β-1,2-N-acetylglucosaminyltransferase 1 in Zebrafish2014
- Author(s)
  Yutaka Tamaru, Eriko Avşar-Ban, Hiroshi Manya, Tamao Endo, Shin’ichi Akiyama
- Journal Title
  
  J. Glycomics Lipidomics
  
  Volume: 4 Issue: 02 Pages: 111-111
- DOI
  10.4172/2153-0637.1000111
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110523, KAKENHI-PROJECT-25293016
[Journal Article] Structural and biochemical characterization of O-mannose-linked HNK-1 glycan expressed on phosphacan in developing mouse brains.2014
- Author(s)
  Morise J, Kizuka Y, Yabuno K, Tonoyama Y, Hashii N, Kawasaki N, Manya H, Miyagoe-Suzuki Y, Takeda S, Endo T, Maeda N, Takematsu H, and Oka S.
- Journal Title
  
  Glycobiology
  
  Volume: 24 Issue: 3 Pages: 314-324
- DOI
  10.1093/glycob/cwt116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23110006, KAKENHI-PUBLICLY-24110523, KAKENHI-PROJECT-24590078, KAKENHI-PROJECT-25293016, KAKENHI-PROJECT-25430081
[Journal Article] Novel POMGnT1 mutations cause muscle-eye-brain disease in Chinese patients2013
- Author(s)
  Jiao H, Manya H, Wang S, Zhang Y, Li X, Xiao J, Yang Y, Kobayashi K, Toda T, Endo T, Wu X, Xiong H.
- Journal Title
  
  Mol Genet Genomics
  
  Volume: 288 Issue: 7-8 Pages: 297-308
- DOI
  10.1007/s00438-013-0749-5
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-23249049, KAKENHI-PUBLICLY-24110523, KAKENHI-PROJECT-25293016
[Journal Article] 糖鎖分析技術の高感度化がもたらす糖鎖研究の新たな展開2013
- Author(s)
  萬谷博、遠藤玉夫
- Journal Title
  
  KAGAKU TO SEIBUTSU
  
  Volume: 51 Issue: 1 Pages: 10-12
- DOI
  10.1271/kagakutoseibutsu.51.10
- NAID
  10031146869
- ISSN
  0453-073X, 1883-6852
- Language
  Japanese
- Data Source
  KAKENHI-PUBLICLY-24110523
[Journal Article] GTDC2 modifies O-mannosylated α-dystroglycan in the endoplasmic reticulum to generate N-acetyl-glucosamine epitopes reactive with CTD110.6 antibody.2013
- Author(s)
  Ogawa M, Nakamura N, Nakayama Y, Kurosaka A, Manya H, Kanagawa M, Endo T, Furukawa K, Okajim T
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 440 Issue: 1 Pages: 88-93
- DOI
  10.1016/j.bbrc.2013.09.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23110008, KAKENHI-PUBLICLY-24110507, KAKENHI-PUBLICLY-24110508, KAKENHI-PUBLICLY-24110516, KAKENHI-PUBLICLY-24110523, KAKENHI-PROJECT-24687017, KAKENHI-PROJECT-25293016, KAKENHI-PROJECT-25670140
[Journal Article] アドスリー2008
- Author(s)
  萬谷博
- Journal Title
  
  老化・老年病研究のための動物実験ガイドブック(日本基礎老化学会編)
  
  Pages: 101-107
- Data Source
  KAKENHI-PROJECT-18790079
[Patent] O-マンノシルグリカン関連化合物および糖鎖伸長プライマーとしてのその使用2021
- Inventor(s)
  田村純一、田村敬裕、遠藤玉夫、萬谷博、星野駿介
- Industrial Property Rights Holder
  鳥取大学、東京都健康長寿医療センター
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-174154
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-17H03987
[Patent] ジストログリカン糖鎖修飾異常に伴う疾患の治療剤及び関連酵素測定法2017
- Inventor(s)
  戸田達史、小林千浩、金川基、遠藤玉夫、萬谷博、和田芳直、田尻道子
- Industrial Property Rights Holder
  神戸大学、東京都健康長寿医療センター、大阪母子センター
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2022
- Data Source
  KAKENHI-PROJECT-17H03987
[Patent] Therapeutic agent for diseases associated with abnormalities in dystroglycan sugar chain modification and method for assaying associated enzyme2017
- Inventor(s)
  Toda T, Manya H, et al.
- Industrial Property Rights Holder
  Kobe Univ., et al.
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 高異型度漿液性卵巣がんにおける糖転移酵素POMGnT1の腫瘍促進因としての役割2023
- Author(s)
  竹岩俊彦、今江理恵子、萬谷博、池田和博、堀江公仁子、井上聡
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] Chemical and chemo-enzymatic synthesis of tandem ribitol phosphate scaffolding of matriglycan.2023
- Author(s)
  Jun-ichi Tamra, Takahiro Tamra, Shunsuke Hoshino, Rieko Imae, Ryuichi Kato, Mizuki Yokono, Mao Nagase, Shiho Ohno, Noriyoshi Manabe, Yoshiki Yamaguchi, Hiroshi Manya, Tamao Endo
- Organizer
  Eurocarb 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] N-glycan expression in multiple organs during aging in mice.2023
- Author(s)
  Keiko Akasaka-Manya, Hisatoshi Hanamatsu, Nobuaki Miura, Jun-ichi Furukawa, Hiroshi Manya, Tamao Endo
- Organizer
  IAGG-AOR2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] O-Man 糖鎖不全による筋委縮モデルマウスの筋病理解析2023
- Author(s)
  丸山詩織、赤阪-萬谷啓子、萬谷博、遠藤玉夫
- Organizer
  第46回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] Endogenous reductase activities for the generation of ribitol-phosphate, a CDP-ribitol precursor, in mammals2023
- Author(s)
  星野駿介、今江理恵子、萬谷博、遠藤玉夫
- Organizer
  GlycoTOKYO 2023
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] 膵癌細胞におけるCDP-グリセロールによるα-ジストログリカン糖鎖伸長阻害の意義2023
- Author(s)
  今江理恵子、萬谷博、濱弘太郎、横山和明、石渡俊行、遠藤玉夫
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] 糖鎖合成基質である糖ヌクレオチドの加齢マウス臓器における変化2023
- Author(s)
  今江理恵子、萬谷博、津元裕樹、三浦ゆり、遠藤玉夫
- Organizer
  第46回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] O-Man β1-4GlcNAc転移酵素POMGNT2の基質特異性の解析2023
- Author(s)
  星野駿介、今江理恵子、水野真盛、蜷川暁、萬谷博、遠藤玉夫
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] Aging-associated changes in the amount of nucleotide sugars, the donor substrates for glycan biosynthesis, in mouse tissues.2023
- Author(s)
  Rieko Imae, Hiroshi Manya, Hiroki Tsumoto, Yuri Miura, Tamao Endo
- Organizer
  IAGG-AOR2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] マンノース型糖鎖の生合成と糖アルコールリン酸による制御2023
- Author(s)
  萬谷博
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] 膵癌由来MIA PaCa-2細胞におけるα-ジストログリカン糖鎖伸長阻害因子CDP-グリセロールの機能解析2023
- Author(s)
  今江理恵子、萬谷博、濱弘太郎、横山和明、石渡俊行、遠藤玉夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] Sialic Acid Linkage-Specific Alkylamidation of O-Linked Glycoproteins and in Combination with β-Elimination in the Presence of Pyrazolone for O-Linked Glycomics2023
- Author(s)
  Ikuko Yokota, Takashi Nishikaze, Hisatoshi Hanamatsu, Hiroshi Manya, Keiko Akasaka-Manya, Jun-Ichi Furukawa
- Organizer
  Glyco26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24759
[Presentation] Sialic Acid Linkage-Specific Alkylamidation of O-Linked Glycoproteins and β-Elimination in the Presence of Pyrazolone.2023
- Author(s)
  Ikuko Yokota, Takashi Nishikaze, Hisatoshi Hanamatsu, Hiroshi Manya, Keiko Akasaka-Manya, Jun-Ichi Furukawa
- Organizer
  Glyco26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] Comprehensive and comparative analysis of N-glycan expression in multiple organs during aging in mice.2022
- Author(s)
  Keiko Akasaka-Manya, Hiroshi Manya, Hisatoshi Hanamatsu, Jun-ichi Furukawa, Tamao Endo
- Organizer
  基礎老化学会
- Data Source
  KAKENHI-PROJECT-23K24759
[Presentation] CDP-エタノールアミン合成酵素PCYT2によるCDP-グリセロール生合成機構の発見およびα-ジストログリカンの機能制御2021
- Author(s)
  今江理恵子、萬谷博、津元裕樹、三浦ゆり、遠藤玉夫
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 筋ジストロフィー症原因遺伝子産物FKRPによるO-マンノース型糖鎖へのリビトールリン酸転移機構2021
- Author(s)
  今江理恵子、桑原直之、萬谷博、加藤龍一、遠藤玉夫
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 間質-細胞相互作用を制御するO-マンノース型糖鎖の生合成機構2021
- Author(s)
  萬谷博
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 筋ジストロフィー症に関わる糖転移酵素POMGNT2の基質認識の分子機構2021
- Author(s)
  露口正人, 桑原直之, 萬谷博, 今江理恵子, 田中智博, 水野真盛, 遠藤玉夫, 加藤龍一
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 構造・生化学から分かってきたO-マンノース型糖鎖の生合成機構2021
- Author(s)
  萬谷博
- Organizer
  第7回日本筋学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] タンデムリビトールリン酸含有O-マンノシルグリカンの系統的合成とその糖鎖機能2021
- Author(s)
  田村純一, 田村敬裕, 真鍋法義, 大野詩歩, 山口芳樹, 萬谷博, 遠藤玉夫
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 哺乳動物細胞におけるリビトールリン酸生合成経路の解析2021
- Author(s)
  星野駿介, 今江理恵子, 萬谷博, 遠藤玉夫
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] CDP-エタノールアミン合成酵素PCYT2によるCDP-グリセロールの合成およびα-ジストログリカンの制御2021
- Author(s)
  今江理恵子, 萬谷博, 津元裕樹, 三浦ゆり, 遠藤玉夫
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 構造解析に基づくO-マンノース型糖鎖の生合成機構2021
- Author(s)
  萬谷博, 今江理恵子, 桑原直之, 田中智博, 露口正人, 水野真盛, 加藤龍一, 遠藤玉夫
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 哺乳類におけるリビトールリン酸産生酵素の解析2021
- Author(s)
  星野駿介、今江理恵子、萬谷博、遠藤玉夫
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] RboP5-3GalNAcbの系統的合成と糖転移受容体機能2021
- Author(s)
  田村純一、田村敬裕、永瀬真央、真鍋法義、大野詩歩、星野駿介、山口芳樹、萬谷博、遠藤玉夫
- Organizer
  日本農芸化学会2022大会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] リビトールリン酸転移酵素FKRPによるO-マンノース型糖鎖伸長機構2020
- Author(s)
  今江理恵子、桑原直之、萬谷博、加藤龍一、遠藤玉夫
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] O-マンノース型糖鎖の伸長過程におけるFKRPによるリビトールリン酸転移機構2020
- Author(s)
  今江理恵子、桑原直之、萬谷博、加藤龍一、遠藤玉夫
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] α-ジストログリカン糖鎖合成阻害因子CDP-グリセロールの定量分析2019
- Author(s)
  今江理恵子, 萬谷博, 津元裕樹, 遠藤玉夫
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] グリセロールリン酸供与体CDP-グリセロールの哺乳動物における定量分析2019
- Author(s)
  今江理恵子、萬谷博、津元裕樹、石渡俊行、遠藤玉夫
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 哺乳動物培養細胞および組織におけるCDP-グリセロールの定量分析2019
- Author(s)
  今江理恵子、萬谷博、津元裕樹、石渡俊行、遠藤玉夫
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] Substrates recognition and oligomerization mechanism of Fukutin-related protein (FKRP).2018
- Author(s)
  Naoyuki Kuwabara, Hiroshi Manya, Rieko Imae, Tomohiro Tanaka, Motoi Kanagawa, Kazuhiro Kobayashi, Tatsushi Toda, Mamoru Mizuno, Toshiya Senda, Tamao Endo, Ryuichi Kato
- Organizer
  11th International Symposium on Glycosyltransferases (GlycoT 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] Inhibitory effect of CDP-glycerol on the synthesis of the O-mannosyl glycan of α-dystroglycan2018
- Author(s)
  Rieko Imae, Hiroshi Manya, Hiroki Tsumoto, Tamao Endo
- Organizer
  首都大学東京バイオコンファレンス2018
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 福山型筋ジストロフィー原因遺伝子産物fukutinのグリセロールリン酸転移活性.2018
- Author(s)
  萬谷博、今江理恵子、津元裕樹、田中智博、水野真盛、金川基、小林千浩、戸田達史、遠藤玉夫
- Organizer
  第4回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] CDP-グリセロール添加によるα-ジストログリカンの機能糖鎖伸長およびラミニン結合能への影響.2018
- Author(s)
  今江理恵子、萬谷博、津元裕樹、遠藤玉夫
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] Biosynthesis of O-mannosyl glycan in mammals.2018
- Author(s)
  Hiroshi Manya
- Organizer
  糖鎖創薬研究拠点キックオフシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 新規糖鎖修飾体グリセロールリン酸によるα-ジストログリカンの機能糖鎖合成阻害.2018
- Author(s)
  今江理恵子、萬谷博、津元裕樹、田中智博、水野真盛、金川基、小林千浩、戸田達史、遠藤玉夫
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 糖鎖異常による先天性筋ジストロフィー症の病態解明と薬学的展.2018
- Author(s)
  萬谷博
- Organizer
  第62回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 新規糖鎖修飾機構の理解に基づく筋ジストロフィー症の病態解明と創薬への応用2018
- Author(s)
  萬谷博
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 糖鎖を利用した先天性筋ジストロフィー症の治療法開発2018
- Author(s)
  萬谷博、赤阪啓子、今江理恵子、遠藤玉夫
- Organizer
  TOBIRA 第7回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] CDP-glycerolはα-ジストログリカンの糖鎖伸長を阻害する.2018
- Author(s)
  今江理恵子、萬谷博、津元裕樹、田中智博、水野真盛、金川基、小林千浩、戸田達史、遠藤玉夫
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] ジストログリカノパチー原因遺伝子産物Protein O-Mannosyl Kinase (POMK)の構造生物学的研究,ポスター2017
- Author(s)
  長江雅倫, Sushil K. Mishra, 根谷崎牧子, 大井里香, 池田明美, 松垣直宏, 明石知子, 萬谷博, 水野真盛, 矢木宏和, 加藤晃一, 千田俊哉, 遠藤玉夫, 禾晃和, 山口芳樹
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] Fukutin-related protein (FKRP)の結晶構造と基質認識機構解析2017
- Author(s)
  桑原直之, 萬谷博, 金川基, 今江理恵子, 田中智博, 小林千浩, 戸田達史, 水野真盛, 遠藤玉夫, 加藤龍一
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] POMGnT1の構造解析による筋ジストロフィー疾患発症機序解明2017
- Author(s)
  桑原直之, 萬谷博, 山田健之, 舘野浩章, 金川基, 小林千浩, 赤阪-萬谷啓子, 弘瀬友理子, 水野真盛, 池口満徳, 戸田達史, 平林淳, 千田俊哉, 遠藤玉夫, 加藤龍一
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 哺乳類細胞発現系によるFukutin-related protein (FKRP)の大量精製と結晶構造決定2017
- Author(s)
  桑原直之, 萬谷博, 今江理恵子, 遠藤玉夫, 千田俊哉, 加藤龍一
- Organizer
  2017年度量子ビームサイエンスフェスタ
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] APP代謝におけるO型糖鎖修飾の影響2017
- Author(s)
  赤阪-萬谷啓子、萬谷博、遠藤玉夫
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] 新規O-マンノース型糖鎖の発見とその異常による先天性筋ジストロフィー症2017
- Author(s)
  萬谷博
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of α-dystroglycan2017
- Author(s)
  Naoyuki Kuwabara, Hiroshi Manya, Takeyuki Yamada, Hiroaki Tateno, Motoi Kanagawa, Kazuhiro Kobayashi, Keiko Akasaka-Manya, Yuriko Hirose, Mamoru Mizuno, Mitsunori Ikeguchi, Tatsushi Toda, Jun Hirabayashi, Toshiya Senda, Tamao Endo, Ryuichi Kato
- Organizer
  4th International Symposium on Glyconjugates (GlycoXXIV)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 筋ジストロフィー症原因遺伝子産物フクチンはジストログリカン糖鎖にグリセロールリン酸を導入する活性を有する2017
- Author(s)
  今江理恵子, 萬谷博, 津元裕樹, 田中智博, 水野真盛, 金川基, 小林千浩, 戸田達史, 遠藤玉夫
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] 筋ジストロフィー症原因遺伝子産物TMEM5によるジストログリカンの機能糖鎖修飾2017
- Author(s)
  萬谷博, 山口芳樹, 金川基, 小林千浩, 田尻道子, 赤阪-萬谷啓子, 川上宏子, 水野真盛, 和田芳直, 戸田達史
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17H03987
[Presentation] O型糖鎖修飾によるAPP代謝への影響2016
- Author(s)
  赤阪-萬谷啓子、川村方希、萬谷博、遠藤玉夫
- Organizer
  第39回日本基礎老化学会大会
- Place of Presentation
  伊勢原市民文化会館（神奈川県・伊勢原市）
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] Analysis of substrate specificity of GTDC2.2016
- Author(s)
  amada, Y., Tsumoto H., Akasaka-Manya, K., Manya, H., Endo, T.
- Organizer
  The 3rd International Symposium on Glyco-Neuro science
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県・淡路市）
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] A novel carbohydrate binding domain of POMGnT1 stem region modulates O-mannosylation sites of α-dystroglycan.2016
- Author(s)
  Kuwabara, N., Manya, H., Yamada, T., Tateno, H., Hirose, Y., Mizuno, M, Ikeguchi, M., Hirabayashi, J., Senda, T., Endo, T., Kato, R.
- Organizer
  The 3rd International Symposium on Glyco-Neuro science
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県・淡路市）
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] Biosynthetic mechanisms of O-mannosyl glycan and muscular dystrophy.2016
- Author(s)
  Manya H.
- Organizer
  The 3rd International Symposium on Glyco-Neuro science
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県・淡路市）
- Year and Date
  2016-01-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] Aβ産生におけるO型糖鎖修飾の影響2016
- Author(s)
  赤阪-萬谷啓子、川村方希、津元裕樹、萬谷博、遠藤玉夫
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] APP代謝におけるppGalNAcT-6の影響2016
- Author(s)
  赤阪-萬谷啓子、川村方希、津元裕樹、萬谷博、遠藤玉夫
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] アミロイド産生と脳アミロイドアンギオパチーを規定する血管内皮細胞のO-GalNAc型糖鎖2016
- Author(s)
  北爪しのぶ、立田由里子、木塚康彦、今牧理恵、加藤雅樹、山口芳樹、田中克典、中の三弥子、斎藤貴志、西道隆臣、萬谷博、遠藤玉夫、橋本康弘、谷口直之
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  高知市文化プラザかるぽーと（高知県・高知市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] andem Ribitol-phosphate structure is required for O-mannosyl glycan biosynthesis and its defect in muscular dystrophy2016
- Author(s)
  Manya H.
- Organizer
  Glycoscience Japan ー The Netherlands Joint Seminar 2016
- Place of Presentation
  ライデン（オランダ）
- Year and Date
  2016-04-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] ドリコールリン酸マンノースの供給におけるPOMT–DPM複合体の働き2015
- Author(s)
  山田健之、萬谷博、遠藤玉夫
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 組換え糖転移酵素POMGnT1のO-結合型糖鎖解析2015
- Author(s)
  津元裕樹、萬谷博、遠藤玉夫、三浦ゆり
- Organizer
  日本質量分析学会第63回質量分析総合討論会
- Place of Presentation
  つくば国際会議場（茨城県・つくば市）
- Year and Date
  2015-06-17
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 小胞体におけるドリコールリン酸マンノースの供給機構の研究2015
- Author(s)
  山田健之、萬谷博、遠藤玉夫
- Organizer
  第88回日本生化学会大会(BMB2015)
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] O-マンノース型糖鎖の生合成と筋ジストロフィー症2015
- Author(s)
  萬谷博
- Organizer
  第88回日本生化学会大会(BMB2015)
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 糖転移酵素POMGnT1の糖鎖認識機構解析2015
- Author(s)
  桑原直之、萬谷博、山田健之、舘野浩章、平林淳、千田俊哉、遠藤玉夫、加藤龍一
- Organizer
  第88回日本生化学会大会(BMB2015)
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] O-Man転移酵素複合体によるドリコールリン酸マンノースの供給メカニズム2015
- Author(s)
  萬谷博、山田健之、遠藤玉夫
- Organizer
  第1回日本筋学会
- Place of Presentation
  国立精神・神経医療研究センター（東京都・小平市）
- Year and Date
  2015-08-08
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 糖転移酵素異常による筋疾患モデルマウスの筋病理解析2015
- Author(s)
  井上貴美子、山田健之、萬谷博、赤阪-萬谷啓子、櫻井洋子、遠藤玉夫
- Organizer
  第38回日本基礎老化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] O-マンノース型糖鎖生合成機構の解析2015
- Author(s)
  萬谷博
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2015-07-31
- Invited
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 組換え糖転移酵素POMGnT1のO-結合型糖鎖解析2015
- Author(s)
  津元裕樹、萬谷博、遠藤玉夫、三浦ゆり
- Organizer
  日本質量分析学会第63回質量分析総合討論会
- Place of Presentation
  つくば国際会議場（茨城県・つくば市）
- Year and Date
  2015-06-17
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] α-Klothoの欠損による糖鎖異常2015
- Author(s)
  生形亮介、赤阪啓子、萬谷博、遠藤玉夫
- Organizer
  首都大バイオコンファレンス2015
- Place of Presentation
  首都大学東京（東京都・八王子市）
- Year and Date
  2015-11-06
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] 老化に伴って増加する非硫酸化グルクロン酸によるCD13の活性変化2015
- Author(s)
  赤阪-萬谷啓子、萬谷博、岡昌吾、遠藤玉夫
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] O型糖鎖修飾によるアミロイドβ産生への影響.2014
- Author(s)
  川村方希、赤阪-萬谷啓子、萬谷博、櫻井洋子、遠藤玉夫
- Organizer
  首都大学東京バイオコンファレンス2014
- Place of Presentation
  東京
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] Functional interaction of POMT and DPM synthase in protein O-mannosylation2014
- Author(s)
  Manya, H., Yamada, T., Takahashi, T., Akasaka-Manya, K., Endo, T.
- Organizer
  Satellite Symposia II in Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research
- Place of Presentation
  Honolulu
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] O-マンノース型糖鎖研究の最近の動向2013
- Author(s)
  萬谷博
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PUBLICLY-24110523
[Presentation] ヒトPOMGnT1のO型糖鎖修飾の解析2013
- Author(s)
  赤阪-萬谷啓子、辛欣、萬谷博、遠藤玉夫
- Organizer
  第86回生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-24110523
[Presentation] α-ジストログリカノパチーの原因遺伝子産物POMGNT1によるO-マンノース型糖鎖合成機構の解析2012
- Author(s)
  萬谷博
- Organizer
  包括脳科学研究推進ネットワーク夏のワークショップ
- Place of Presentation
  仙台
- Year and Date
  2012-07-24
- Data Source
  KAKENHI-PUBLICLY-24110523
[Presentation] 小胞体におけるO-マンノース転移酵素複合体の解析2012
- Author(s)
  萬谷博
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-24110523
[Presentation] O-マンノース転移酵素とドリコールリン酸マンノース合成酵素の相互作用の解析2012
- Author(s)
  萬谷博
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Year and Date
  2012-06-17
- Data Source
  KAKENHI-PUBLICLY-24110523
[Presentation] klothoマウスを用いた抗老化研究2009
- Author(s)
  萬谷博
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都府京都市京都国際会館
- Data Source
  KAKENHI-PROJECT-18790079
[Presentation] klotho マウスを用いた抗老化研究2009
- Author(s)
  萬谷博、赤阪-萬谷啓子、遠藤玉夫
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18790079
[Presentation] アルツハイマー病患者の脳における糖転移酵素の発現解析
- Author(s)
  萬谷博、赤阪-萬谷啓子、遠藤玉夫
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Invited
- Data Source
  KAKENHI-PROJECT-26460090
[Presentation] Klothoマウス腎臓における非硫酸化HNK-1糖鎖の増加.
- Author(s)
  赤阪-萬谷啓子、萬谷博、木塚康彦、岡昌吾、遠藤玉夫
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] Analysis of protein O-mannosyltransferase complex formation in the endoplasmic reticulum.
- Author(s)
  Endo, T., Yamada, T., Takahashi, T., Akasaka-Manya, K., Manya, H.
- Organizer
  th International Symposium on Glycosyltransferases (Glyco-T 2014)
- Place of Presentation
  Porto, Portugal
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 糖鎖修飾におけるドリコールリン酸マンノース供給の制御機構.
- Author(s)
  山田健之、萬谷博、遠藤玉夫
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] α-Klothoの欠損によって生じる非硫酸化HNK-1糖鎖の蓄積.
- Author(s)
  赤阪－萬谷啓子、萬谷博、木塚康彦、岡昌吾、遠藤玉夫
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] Bisecting GlcNAc欠損によるアルツハイマー病抑制に関する研究
- Author(s)
  木塚康彦、北爪しのぶ、藤縄玲子、斉藤貴志、岩田修永、西道隆臣、中の三弥子、山口芳樹、橋本康弘、Matthias Staufenbiel、初田裕幸、村山繁雄、萬谷博、遠藤玉夫、谷口直之
- Organizer
  第33回日本糖質学会年
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 小胞体におけるマンノース付加の制御機構.
- Author(s)
  山田健之、萬谷博、遠藤玉夫
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] アルツハイマー病患者の脳における糖転移酵素の発現解析.
- Author(s)
  萬谷博、赤阪-萬谷啓子、遠藤玉夫
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Invited
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] Functional interaction of POMT and DPM synthase in protein O-mannosylation
- Author(s)
  Manya, H., Yamada, T., Takahashi, T., Akasaka-Manya, K., Endo, T.
- Organizer
  Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research
- Place of Presentation
  Honolulu
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 神経系に発現するLewis X抗原のキャリアタンパク質および生合成酵素の解析.
- Author(s)
  中川直樹、萬谷博、家治翔平、竹松弘、遠藤玉夫、神奈木玲児、吉原亨、浅野雅秀、岡昌吾
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 糖鎖修飾酵素POMGnT1ステムドメインの機能同定と糖鎖認識機構解析.
- Author(s)
  桑原直之、萬谷博、舘野浩章、平林淳、遠藤玉夫、千田俊哉、加藤龍一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] GTDC2はαジストログリカンのO-ManにCTD110.6抗体が認識するGlcNAcを修飾する
- Author(s)
  小川光貴、澤口翔伍、中村直介、中山喜明、黒坂光、萬谷博、金川基、遠藤玉夫、古川鋼一、岡島徹也
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PUBLICLY-26110727
[Presentation] 先天性筋ジストロフィー症の原因遺伝子産物POMGnT1の糖鎖修飾
- Author(s)
  辛欣、川村方希、赤阪-萬谷啓子、萬谷博、遠藤玉夫
- Organizer
  首都大学東京バイオコンファレンス
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-24110523
[Presentation] Bisecting GlcNAc欠損によるアルツハイマー病抑制に関する研究
- Author(s)
  木塚康彦、北爪しのぶ、藤縄玲子、斉藤貴志、岩田修永、西道隆臣、中の三弥子、山口芳樹、橋本康弘、Matthias Staufenbiel、初田裕幸、村山繁雄、萬谷博、遠藤玉夫、谷口直之
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-26460090

1. KATO Ryuichi (50240833)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Kanagawa Motoi (00448044)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. ENDO Tamao (30168827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. MAKIYO Hisayoshi (00467474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MATSUGAKI Naohiro (50342598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMADA Yusuke (20391708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Kira Jun-ichi (40183305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田村純一 (30221401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 片野坂友紀 (60432639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山口芳樹 (90323451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松下拓也 (00533001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山崎亮 (10467946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 藤井敬之 (30822481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 緒方英紀 (90778838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 磯部紀子 (60452752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 海田賢一 (40531190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 渡邉充 (30748009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中村優理 (40822375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 永森收志 (90467572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 古川潤一 (30374193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. 三浦信明 (80372267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 小川治夫 (40292726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KAWASAKI Nana

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. MORISE Jyoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. IMAE Rieko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. YAGI Hirokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 岡昌吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 小林千浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 戸田達史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 竹松弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 加藤晃一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 橋本康弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 古川鋼一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Manya Hiroshi 萬谷 博

MANYA Hiroshi 萬谷 博

Research Projects

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Co-Researchers

Molecular basis and physiological significance of O-mannosyl glycans in mammalsPrincipal Investigator

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包括的組織グライコームによる糖鎖分子ネットワークの構築と老化の客観的評価

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Elucidation of the molecular basis of novel ribitol phosphate modifications and their application to the development of treatments for muscular dystrophy

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Elucidation of autoimmune mechanisms and developement of novel therapy for demyelinating diseases based on genetic and envrionmental risk factors and disease-specific anti-neural antibodies

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Understanding of the mechanism of ribitol-phosphate modification and application of its physiological function to therapy

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Structural diversity and biosynthetic mechanisms of O-mannosyl glycans in mammalsPrincipal Investigator

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Crystallography of membrane protein complex by S-SAD method

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脳発生過程におけるO-マンノース型糖鎖の機能解析Principal Investigator

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Role of glycosylation in processing of APPPrincipal Investigator

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脳発生過程におけるＯーマンノース型糖鎖の機能解析Principal Investigator

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Study of abnormal activation of calpain by klotho protein deficiencyPrincipal Investigator

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Klotho蛋白質によるカルパインの活性制御機構の解析Principal Investigator

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アミロイド前駆体蛋白質糖鎖変化の老人斑形成における意義Principal Investigator

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Manya Hiroshi 萬谷博

MANYA Hiroshi 萬谷博