Watanabe Mitsuru 渡邉充

Researcher Number	30748009
Affiliation *help	2018 : 九州大学, 医学研究院, 助教 2016 – 2017 : 九州大学, 大学病院, 医員 2015 : 九州大学, 大学病院, その他
Review Section/Research Field	Principal Investigator Neurology Except Principal Investigator General internal medicine and related fields / Neurology
Keywords	Principal Investigator 多発性硬化症 / グリア細胞 / インターフェロンγ / 乳酸担体 / アストロサイト / ギャップ結合 / 中枢神経脱髄性疾患 / Cx43 / 中枢神経脱髄疾患 / グルコース担体 … More Except Principal Investigator 多発性硬化症 / TGFbeta / アストログリア / 視神経脊髄炎 / オリゴデンドログリア / 肥厚性硬膜炎 / コネキシン / 動物モデル / ミクログリア Less

グルコース・乳酸担体を標的とした中枢脱髄疾患のエネルギー供給機構修復治療の開発Principal InvestigatorOngoing
- Principal Investigator
  
  渡邉充
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Establishment of world-premier pachymeningitis animal model and development of new therapeutic option targeting TGF-beta.Ongoing
- Principal Investigator
  
  吉良潤一
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Challenging Research (Exploratory)
- Research Field
  
  General internal medicine and related fields
- Research Institution
  Kyushu University
Induction of concentric demyelinating lesion in glia-specific connesin conditional deficient mice.
- Principal Investigator
  
  Kira Jun-ichi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Development of a novel treatment strategy based on the mechanisms that pathogenic T cells induce loss of glial connexins in CNS demyelinating disordersPrincipal Investigator
- Principal Investigator
  
  Watanabe Mitsuru
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University

All 2017 2016 2015

All Journal Article Presentation

[Journal Article] The relationship between Th1 cells and astrocytic connexin 43 gap junctions in multiple sclerosis.2017
- Author(s)
  Watanabe M, Yamasaki R, Kira J.
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume : 印刷中
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19489
[Journal Article] Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation.2016
- Author(s)
  Watanabe M, Masaki K, Yamasaki R, Kawanokuchi J, Takeuchi H, Matsushita T, Suzumura A, Kira JI.
- Journal Title
  
  Scientific reports
  
  Volume : 6 Pages : 38387-38387
- DOI
  10.1038/srep38387
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-25117001, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-16H02657, KAKENHI-PROJECT-26461295, KAKENHI-PROJECT-15K15341, KAKENHI-PROJECT-15K19489
[Presentation] IFN-gamma inhibit the expression of connexin43 in astrocytes via activation of microglia2016
- Author(s)
  渡邉　充
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K19489
[Presentation] IFNγ reduces expression of connexin43 in astrocytes via activation of microglia2016
- Author(s)
  Watanabe M, Masaki K, Yamasaki R, Kawanokuchi J, Takeuchi H, Suzumura A, Kira J
- Organizer
  32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis
- Place of Presentation
  ロンドン (ExCeL London)
- Year and Date
  2016-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19489
[Presentation] IFNγはミクログリアにIL-1β/TNFαを産生させてアストロサイトコネキシン43発現を低下させる2016
- Author(s)
  渡邉充、眞﨑勝久、山﨑亮、川ノ口潤、竹内英之、錫村明生、吉良潤一
- Organizer
  第28回日本神経免疫学会学術集会
- Place of Presentation
  長崎（長崎ブリックホール）
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-15K19489
[Presentation] IFN-gamma inhibit the expression of connexin43 in astrocytes via activation of microglia2016
- Author(s)
  Watanabe M, Masaki K, Yamasaki R, Kawanokuchi J, Takeuchi H, Suzumura A, Kira J
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸市（神戸コンベンションセンター）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K19489
[Presentation] Th1細胞によるアストロサイトのコネキシン発現抑制作用2015
- Author(s)
  渡邉　充
- Organizer
  第27回日本神経免疫学会学術集会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-15K19489
[Presentation] Th1 cells inhibit the expression of connexins in astrocytes2015
- Author(s)
  Mitsuru Watanabe
- Organizer
  31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19489
[Presentation] Th1 cells inhibit the expression of connexins in astrocytes2015
- Author(s)
  渡邉　充
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15K19489

1. Kira Jun-ichi (40183305)

# of Collaborated Projects : 3results

# of Collaborated Products : 6results
2. 山口浩雄 (00701830)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
3. 真崎勝久 (90612903)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
4. 山崎亮 (10467946)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
5. 篠田紘司 (70747998)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. YAMASAKI Ryo

# of Collaborated Projects : 1results

# of Collaborated Products : 5results
7. MATSUSHITA Takuya

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
8. MASAKI Katsuhisa

# of Collaborated Projects : 1results

# of Collaborated Products : 5results
9. SUZUMURA Akio

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
10. TAKEUCHI Hideyuki

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
11. KAWANOKUCHI Jun

# of Collaborated Projects : 1results

# of Collaborated Products : 4results

Watanabe Mitsuru 渡邉 充

Research Projects

Research Products

Co-Researchers

グルコース・乳酸担体を標的とした中枢脱髄疾患のエネルギー供給機構修復治療の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of world-premier pachymeningitis animal model and development of new therapeutic option targeting TGF-beta.Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of concentric demyelinating lesion in glia-specific connesin conditional deficient mice.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel treatment strategy based on the mechanisms that pathogenic T cells induce loss of glial connexins in CNS demyelinating disordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The relationship between Th1 cells and astrocytic connexin 43 gap junctions in multiple sclerosis.2017

Author(s)

Journal Title

Data Source

[Journal Article] Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] IFN-gamma inhibit the expression of connexin43 in astrocytes via activation of microglia2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] IFNγ reduces expression of connexin43 in astrocytes via activation of microglia2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] IFNγはミクログリアにIL-1β/TNFαを産生させてアストロサイトコネキシン43発現を低下させる2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] IFN-gamma inhibit the expression of connexin43 in astrocytes via activation of microglia2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Th1細胞によるアストロサイトのコネキシン発現抑制作用2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Th1 cells inhibit the expression of connexins in astrocytes2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Th1 cells inhibit the expression of connexins in astrocytes2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Watanabe Mitsuru 渡邉充