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Eguchi Ryoji  江口 良二

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EGUTI Ryoji  江口 良二

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Researcher Number 00461088
Other IDs
Affiliation (based on the past Project Information) *help 2016 – 2020: 兵庫医科大学, 医学部, 助教
2013 – 2014: 兵庫医科大学, 医学部, 助教
2012: 兵庫医科大学, 医学部, ポストドクター
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor diagnostics / Hematology
Except Principal Investigator
Applied health science / Clinical oncology
Keywords
Principal Investigator
VEGF / 血管新生 / 3次元培養 / 塩基性繊維芽細胞増殖因子 / 繊維芽細胞増殖因子-2 / 肝細胞癌由来増殖因子 / 血管内皮増殖因子 / FGF-2 / HDGF / 無血清培養 … More / 非小細胞肺癌 / progranulin / granulin / progranulin (PGRN) / granulin (GRN) / 血管内皮増殖因子 (VEGF) / 悪性中皮腫 / caspase / calcineurin / カスパーゼ / Akt / ERK1/2 / FK506 / アポトーシス / 細胞死 / 管腔崩壊 / 免疫抑制剤 / 血管内皮障害 / 血管内皮細胞 / 血管生物学 … More
Except Principal Investigator
Japanese paradox / 血管細胞 / 血管機能 / 動脈硬化 / 赤血球 / 血小板 / 血管平滑筋細胞 / 人種差 / 虚血性心疾患 / マイクロRNA / ダサチニブ / スフェロイド / Lyn / Fyn / アポトーシス / 中皮腫 / Srcファミリーキナーゼ Less
  • Research Projects

    (5 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (7 People)
  •  Identification of VEGF-independent angiogenic factors in non-small cell lung cancerPrincipal Investigator

    • Principal Investigator
      Eguchi Ryoji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Hyogo Medical University
  •  Clarification of the mechanism for Japanese paradox regarding ischemic heart disease by using microRNA

    • Principal Investigator
      Ichiro Wakabayashi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied health science
    • Research Institution
      Hyogo Medical University
  •  Exploration of novel VEGF-independent angiogenic factors in malignant mesotheliomaPrincipal Investigator

    • Principal Investigator
      Eguchi Ryoji
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor diagnostics
    • Research Institution
      Hyogo Medical University
  •  Role of Src-family kinase in the progression of malignant tumor cells and its clinical implication

    • Principal Investigator
      FUJIMORI Yoshihiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical oncology
    • Research Institution
      Hyogo Medical University
  •  Analysis of molecular mechanism of FK506-induced endothelial dysfunctionPrincipal Investigator

    • Principal Investigator
      EGUCHI Ryoji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Hyogo Medical University

All 2020 2019 2017 2016 2014 2013 2012 Other

All Journal Article Presentation

  • [Journal Article] Relationships among erythrocyte-derived microRNAs in serum of healthy donors2020

    • Author(s)
      Wakabayashi I, Sotoda Y, Eguchi R
    • Journal Title

      Clinica Chimica Acta

      Volume: 507 Pages: 7-10

    • DOI

      10.1016/j.cca.2020.03.034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H02184
  • [Journal Article] Contribution of platelet-derived microRNAs to serum microRNAs in healthy men2020

    • Author(s)
      Wakabayashi I, Sotoda Y, Eguchi R
    • Journal Title

      Platelets

      Volume: 30 Issue: 7 Pages: 1-4

    • DOI

      10.1080/09537104.2020.1810223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H02184
  • [Journal Article] HDGF enhances VEGFーdependent angiogenesis and FGFー2 is a VEGFーindependent angiogenic factor in nonーsmall cell lung cancer2020

    • Author(s)
      Eguchi R and Wakabayashi I
    • Journal Title

      Oncology Reports

      Volume: - Pages: 14-28

    • DOI

      10.3892/or.2020.7580

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07278
  • [Journal Article] Blood levels of microRNAs associated with ischemic heart disease differ between Austrians and Japanese: a pilot study2020

    • Author(s)
      Wakabayashi I, Eguchi R, Sotoda Y, von Lewinski D, Sourij H, Daimon T, Groschner K, Rainer PP
    • Journal Title

      Scientific Reports

      Volume: 10(1) Issue: 1 Pages: 13628-13628

    • DOI

      10.1038/s41598-020-69332-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H02184
  • [Journal Article] Progranulin and granulin-like protein as novel VEGF-independent angiogenic factors derived from human mesothelioma cells2017

    • Author(s)
      Eguchi R, Nakano T, Wakabayashi I
    • Journal Title

      Oncogene

      Volume: 36 Issue: 5 Pages: 714-722

    • DOI

      10.1038/onc.2016.226

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K14626
  • [Journal Article] Recombinant human soluble thrombomodulin attenuates FK506- induced endothelial dysfunction through prevention of Akt inactivation.2014

    • Author(s)
      Eguchi R, Fujimori Y, Okada M, Tamaki H, Wakabayashi I, Ogawa H.
    • Journal Title

      Experimental Cell Research

      Volume: 323 Issue: 1 Pages: 112-117

    • DOI

      10.1016/j.yexcr.2014.02.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591434, KAKENHI-PROJECT-24790985
  • [Journal Article] Serum thioredoxin-1 as a diagnostic marker for malignant peritoneal mesothelioma.2013

    • Author(s)
      Tabata C, et al.
    • Journal Title

      J Clin Gastroenterol

      Volume: 47 Issue: 1 Pages: e7-e11

    • DOI

      10.1097/mcg.0b013e31824e901b

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591167, KAKENHI-PROJECT-24790985
  • [Journal Article] FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway.2013

    • Author(s)
      Eguchi R, Kubo S, Ohta T, Kunimasa K, Okada M, Tamaki H, Kaji K, Wakabayashi I, Fujimori Y, Ogawa H
    • Journal Title

      Cellular Signalling

      Volume: 25 Issue: 9 Pages: 1731-1738

    • DOI

      10.1016/j.cellsig.2013.05.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Journal Article] Different mechanisms causing loss of mismatched human leukocyte antigens in relapsing t(6;11)(q27;q23) acute myeloid leukemia after haploidentical transplantation.2012

    • Author(s)
      Tamaki H, Fujioka T, Ikegame K, Yoshihara S, Kaida K, Taniguchi K, Kato R, Tokugawa T, Nakata J, Inoue T, Yano A, Eguchi R, Okada M, Maruya E, Saji H, Ogawa H.
    • Journal Title

      European Journal of Haematology

      Volume: 89 Issue: 6 Pages: 497-500

    • DOI

      10.1111/ejh.12017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Journal Article] Deficiency of Fyn protein is prerequisite for apoptosis induced by Src family kinase inhibitors in human mesothelioma cells2012

    • Author(s)
      Eguchi R, Kubo S, Takeda H, Ogawa H, et al.(8人中6番)
    • Journal Title

      Carcinogenesis

      Volume: 33 Issue: 5 Pages: 969-975

    • DOI

      10.1093/carcin/bgs109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591252, KAKENHI-PROJECT-23591167, KAKENHI-PROJECT-24501361
  • [Presentation] HDGF enhances VEGF-dependent angiogenesis and FGF-2 regulates VEGF-independent angiogenesis in non-small cell lung cancer2020

    • Author(s)
      江口良二
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07278
  • [Presentation] ヒト非小細胞肺癌細胞株EBC-1において 血管内皮増殖因子と肝癌由来増殖因子は相乗的に血管新生を誘導する2019

    • Author(s)
      江口良二、若林一郎
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K07278
  • [Presentation] 悪性中皮腫においてProgranulinとgranulin様タンパク質はVEGF非依存性の新規血管新生因子である2017

    • Author(s)
      江口良二、若林一郎
    • Organizer
      第69回日本細胞生物学会
    • Data Source
      KAKENHI-PROJECT-16K14626
  • [Presentation] Progranulin and granulin-like protein as novel VEGF-independent angiogenic factors derived from human mesothelioma cells2016

    • Author(s)
      江口良二、中野孝司、若林一郎
    • Organizer
      第24回日本血管生物医学会学術集会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2016-12-08
    • Data Source
      KAKENHI-PROJECT-16K14626
  • [Presentation] Novel VEGF-independent angiogenic factors derived from human mesothelioma cells2016

    • Author(s)
      江口良二
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K14626
  • [Presentation] プログラニュリンとグラニュリン様タンパク質はヒト中皮腫細胞由来の新規血管新生因子である2016

    • Author(s)
      江口良二、中野孝司、若林一郎
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16K14626
  • [Presentation] FK506はcalcineurin阻害やcaspase経路とは独立してAktとERK1/2活性の減衰により血管内皮障害を誘導する2013

    • Author(s)
      江口良二、藤盛好啓、久保秀司、小川啓恭、若林一郎
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Presentation] SFK inhibition overcomes resistance to anoikis and facilitates cisplatin-induced apoptosis in human mesothelioma cells.2013

    • Author(s)
      江口良二、田端千春、小川啓恭、中野孝司、藤盛好啓
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Presentation] FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway.2013

    • Author(s)
      江口良二、藤盛好啓、久保秀司、小川啓恭、若林一郎
    • Organizer
      第21回日本血管生物医学会学術集会
    • Place of Presentation
      千里阪急ホテル
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Presentation] Recombinant thrombomodulin suppresses FK506-induced endothelial death by preventing Akt inactivation.2013

    • Author(s)
      江口良二、藤盛好啓、岡田昌也、若林一郎、小川啓恭
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌市教育文化会館
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Presentation] A complex of FK506 and FK506-binding protein 12 is involved in FK506-induced breakdown of capillary-like tube structures independently of calcineurin inhibition.2012

    • Author(s)
      江口良二、藤盛好啓、久保秀司、小川啓恭
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Presentation] Deficiency of Fyn Protein Is Prerequisite for Apoptosis Induced by Src Family Kinase Inhibitors in Human Mesothelioma Cells2012

    • Author(s)
      江口良二、藤盛好啓、小川啓恭
    • Organizer
      第21回日本Cell Death学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24501361
  • [Presentation] Recombinant thrombomodulin suppresses FK506-induced endothelial cell death.2012

    • Author(s)
      江口良二、岡田昌也、藤盛好啓、相馬俊裕、小川啓恭
    • Organizer
      第74回日本血液学会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Presentation] FK506 binding protein 12 is involved in FK506-induced endothelial dysfunction.2012

    • Author(s)
      江口良二、藤盛好啓、久保秀司、小川啓恭
    • Organizer
      第74回日本血液学会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Presentation] 組換え型トロンボモジュリンはFK506が誘導するAktの不活性化により引き起こされる血管内皮障害を抑制する

    • Author(s)
      江口良二、藤盛好啓、岡田昌也、玉置広哉、若林一郎、小川啓恭
    • Organizer
      第37回日本造血細胞移植学会
    • Place of Presentation
      神戸国際会議場・神戸ポートピアホテル
    • Year and Date
      2015-03-05 – 2015-03-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790985
  • [Presentation] Recombinant human soluble thrombomodulin attenuates FK506-induced endothelial dysfunction through prevention of Akt inactivation

    • Author(s)
      江口良二、藤盛好啓、小川啓恭、若林一郎
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24790985
  • 1.  Ichiro Wakabayashi (70220829)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 2.  FUJIMORI Yoshihiro (20229058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  KUBO Syuji (10441320)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  大門 貴志 (40372156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  TABATA Chiharu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  小川 啓恭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  岡田 昌也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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