Moriwaki Kazumasa 森脇一将

… Alternative Names

MORIWAKI Kazumasa 森脇一将

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Researcher Number	00467656
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 大阪医科薬科大学, 医学部, 講師 2021 – 2023: 大阪医科薬科大学, 医学部, 講師 2017 – 2020: 大阪医科大学, 医学部, 助教 2012: 神戸大学, 大学院・医学研究科, グローバルCOE 研究員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Pathological medical chemistry Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / General anatomy (including Histology/Embryology)
Keywords	Principal Investigator 癌 / O-GlcNAc修飾 / がん微小環境 / 癌転移 / 癌微小環境 / 糖鎖 / p38 / NF-κB / 炎症性サイトカイン Except Principal Investigator O-GlcNAc 修飾 … More / FBXL2 / FOXM1 / O-GlcNAc修飾 / 血管 / リンパ管 / 胎生期浮腫 / 発生 / 遺伝子変異 / マウス / 形態形成学 / 発生学 Less

可逆的糖鎖修飾が生み出す癌微小環境の特性と転移ニッチ形成の分子機序の解明Principal Investigator
- Principal Investigator
  
  森脇一将
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
O-GlcNAc修飾による癌微小環境制御機能の解析Principal Investigator
- Principal Investigator
  
  森脇一将
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Development of novel diagnosis and therapy in cancer targetting reversible system of intracellular glycosylation
- Principal Investigator
  
  Toshihisa Takeuchi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Role of TME O-GlcNAcylation in cancer proliferationPrincipal Investigator
- Principal Investigator
  
  Moriwaki Kazumasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Medical College
Pathology and molecular mechanism of embryonic edema in mice carrying endothelial gene mutations
- Principal Investigator
  
  HIRASHIMA Masanori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kobe University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Differential expression of TRKB tyrosine kinase in the two histological types of parotid salivary duct carcinoma with cancer aggressiveness2024
- Author(s)
  Moriwaki Kazumasa、Ayani Yusuke、Kuwabara Hiroko、Terada Tetsuya、Higashino Masaaki、Kawata Ryo
- Journal Title
  
  Oral Oncology
  
  Volume: 151 Pages: 106751-106751
- DOI
  10.1016/j.oraloncology.2024.106751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07160
[Journal Article] O-GlcNAcylation-induced GSK-3β activation deteriorates pressure overload-induced heart failure via lack of compensatory cardiac hypertrophy in mice2023
- Author(s)
  Matsuno Mahito、Yokoe Shunichi、Nagatsuka Takehiro、Morihara Hirofumi、Moriwaki Kazumasa、Asahi Michio
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 14 Pages: 1122125-1122125
- DOI
  10.3389/fendo.2023.1122125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07160
[Journal Article] Intravenous injection of iPS cell-derived endothelial progenitor cells prevents miscarriage by releasing pro-angiogenic factors in a mouse model of recurrent spontaneous abortion.2023
- Author(s)
  Morita N, Morihara H, Moriwaki K, Daimon A, Asahi M, Ohmichi M.
- Journal Title
  
  Bulletin of Osaka Medical and Pharmaceutical Univ.
  
  Volume: 69 Pages: 21-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07160
[Journal Article] BDNF/TRKB axis provokes EMT progression to induce cell aggressiveness via crosstalk with cancer-associated fibroblasts in human parotid gland cancer2022
- Author(s)
  Moriwaki Kazumasa、Wada Masaki、Kuwabara Hiroko、Ayani Yusuke、Terada Tetsuya、Higashino Masaaki、Kawata Ryo、Asahi Michio
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 17553-17553
- DOI
  10.1038/s41598-022-22377-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07160, KAKENHI-PROJECT-21K09641
[Journal Article] O-GlcNAcylation-mediated Degradation of FBXL2 Stabilizes FOXM1 to Induce Cancer Progression.2020
- Author(s)
  Y Ueda, K Moriwaki, T Takeuchi, K Higuchi, and M Asahi.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 521 Issue: 3 Pages: 632-638
- DOI
  10.1016/j.bbrc.2019.10.164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07762, KAKENHI-PROJECT-17K08678
[Journal Article] Augmented <i>O</i>-GlcNAcylation alleviates inflammation-mediated colon carcinogenesis via suppression of acute inflammation2018
- Author(s)
  Hirata Y, Nakagawa T, Moriwaki K, Koubayashi E, Kakimoto K, Takeuchi T, Inoue T, Higuchi K, Asahi M
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 62 Issue: 3 Pages: 221-229
- DOI
  10.3164/jcbn.17-106
- NAID
  130006730767
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08678, KAKENHI-PROJECT-16K09296
[Journal Article] Augmented O-GlcNAcylation of AMP-activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line2017
- Author(s)
  Moriwaki K, Asahi M.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 15 Issue: 9 Pages: 1287-1298
- DOI
  10.1158/1541-7786.mcr-16-0499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08678
[Presentation] Elevated O-GlcNAcylation in TME enhances metastasis of PAN02 pancreatic adenocarcinoma.2023
- Author(s)
  Kazumasa Moriwaki
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07160
[Presentation] O-GlcNAcylation-mediated regulation of FOXM1 expression through its ubiquitination in a human gastric adenocarcinoma cell line, NUGC-3.2021
- Author(s)
  K Moriwaki, Y Ueda, T Takeuchi, K Higuchi, and M Asahi.
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19K07762
[Presentation] O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 oncogenic transcription factor to promote cancer progression.2020
- Author(s)
  K Moriwaki, Y Ueda, K Higuchi, and M Asahi.
- Organizer
  第93回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19K07762
[Presentation] Elevated O-GlcNAcylation increases FOXM1 protein via suppression of its poly-ubiquitination and subsequent proteasomal degradation.2019
- Author(s)
  Y Ueda, K Moriwaki, N Sugawara, M Fukumoto, S Harada, K Ota, Y Kojima, T Takeuchi, K Higuchi, and M Asahi.
- Organizer
  Digestive Disease Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07762
[Presentation] Elevated O-GlcNAcylation increases FOXM1 via suppression of FBXL2-mediated its poly-ubiquitination.2019
- Author(s)
  Moriwaki K, Higuchi K, Asahi M.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08678
[Presentation] Elevated O-GlcNAcylation increases FOXM1 protein via suppression of its poly-ubiquitination and subsequent proteasomal degradation.2019
- Author(s)
  Ueda Y, Moriwaki K, Sugawara N, Fukumoto M, Harada S, Ota K, Kojima Y, Takeuchi T, Higuchi K, Asahi M.
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08678
[Presentation] O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 oncogenic transcription factor to promote cancer progression.2019
- Author(s)
  Moriwaki K, Ueda Y, Higuchi K, Asahi M.
- Organizer
  第93回日本薬理学会年
- Data Source
  KAKENHI-PROJECT-17K08678
[Presentation] Elevated O-GlcNAcylation increases FOXM1 via suppression of FBXL2-mediated its poly-ubiquitination.2019
- Author(s)
  K Moriwaki, K Higuchi, and M Asahi.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07762

1. 朝日通雄 (10397614)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. HIRASHIMA Masanori (40383757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. DING Guo (00514697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Toshihisa Takeuchi (30445986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Moriwaki Kazumasa 森脇 一将

MORIWAKI Kazumasa 森脇 一将

Research Projects

Research Products

Co-Researchers

可逆的糖鎖修飾が生み出す癌微小環境の特性と転移ニッチ形成の分子機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

O-GlcNAc修飾による癌微小環境制御機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel diagnosis and therapy in cancer targetting reversible system of intracellular glycosylation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of TME O-GlcNAcylation in cancer proliferationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathology and molecular mechanism of embryonic edema in mice carrying endothelial gene mutations

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differential expression of TRKB tyrosine kinase in the two histological types of parotid salivary duct carcinoma with cancer aggressiveness2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] O-GlcNAcylation-induced GSK-3β activation deteriorates pressure overload-induced heart failure via lack of compensatory cardiac hypertrophy in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intravenous injection of iPS cell-derived endothelial progenitor cells prevents miscarriage by releasing pro-angiogenic factors in a mouse model of recurrent spontaneous abortion.2023

Author(s)

Journal Title

Data Source

[Journal Article] BDNF/TRKB axis provokes EMT progression to induce cell aggressiveness via crosstalk with cancer-associated fibroblasts in human parotid gland cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] O-GlcNAcylation-mediated Degradation of FBXL2 Stabilizes FOXM1 to Induce Cancer Progression.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Augmented <i>O</i>-GlcNAcylation alleviates inflammation-mediated colon carcinogenesis via suppression of acute inflammation2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Augmented O-GlcNAcylation of AMP-activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Elevated O-GlcNAcylation in TME enhances metastasis of PAN02 pancreatic adenocarcinoma.2023

Author(s)

Organizer

Data Source

[Presentation] O-GlcNAcylation-mediated regulation of FOXM1 expression through its ubiquitination in a human gastric adenocarcinoma cell line, NUGC-3.2021

Author(s)

Organizer

Data Source

Moriwaki Kazumasa 森脇一将

MORIWAKI Kazumasa 森脇一将