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Moriwaki Kazumasa  森脇 一将

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MORIWAKI Kazumasa  森脇 一将

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Researcher Number 00467656
Other IDs
Affiliation (Current) 2022: 大阪医科薬科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2021: 大阪医科薬科大学, 医学部, 助教
2017 – 2020: 大阪医科大学, 医学部, 助教
2012: 神戸大学, 大学院・医学研究科, グローバルCOE 研究員
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / Basic Section 50010:Tumor biology-related
Except Principal Investigator
General anatomy (including Histology/Embryology) / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
O-GlcNAc修飾 / 癌 / 炎症性サイトカイン / NF-κB / p38 / 糖鎖 / 癌微小環境
Except Principal Investigator
発生学 / 形態形成学 / マウス … More / 遺伝子変異 / 発生 / 胎生期浮腫 / リンパ管 / 血管 / O-GlcNAc修飾 / FOXM1 / FBXL2 / O-GlcNAc 修飾 Less
  • Research Projects

    (4 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (7 People)
  •  O-GlcNAc修飾による癌微小環境制御機能の解析Principal Investigator

    • Principal Investigator
      森脇 一将
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  Development of novel diagnosis and therapy in cancer targetting reversible system of intracellular glycosylation

    • Principal Investigator
      竹内 利寿
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Osaka Medical College
  •  Role of TME O-GlcNAcylation in cancer proliferationPrincipal Investigator

    • Principal Investigator
      Moriwaki Kazumasa
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka Medical College
  •  Pathology and molecular mechanism of embryonic edema in mice carrying endothelial gene mutations

    • Principal Investigator
      HIRASHIMA Masanori
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Kobe University

All 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 to induce cancer progression.2020

    • Author(s)
      Y Ueda, K Moriwaki, T Takeuchi, K Higuchi, and M Asahi.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 521 Pages: 632-638

    • DOI

      10.1016/j.bbrc.2019.10.164

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07762, KAKENHI-PROJECT-17K08678
  • [Journal Article] Augmented <i>O</i>-GlcNAcylation alleviates inflammation-mediated colon carcinogenesis via suppression of acute inflammation2018

    • Author(s)
      Hirata Y, Nakagawa T, Moriwaki K, Koubayashi E, Kakimoto K, Takeuchi T, Inoue T, Higuchi K, Asahi M
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 3 Issue: 3 Pages: 221-229

    • DOI

      10.3164/jcbn.17-106

    • NAID

      130006730767

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08678, KAKENHI-PROJECT-16K09296
  • [Journal Article] Augmented O-GlcNAcylation of AMP-activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line2017

    • Author(s)
      Moriwaki K, Asahi M.
    • Journal Title

      Mol Cancer Res.

      Volume: 15 Pages: 1287-1298

    • DOI

      10.1158/1541-7786.mcr-16-0499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08678
  • [Presentation] O-GlcNAcylation-mediated regulation of FOXM1 expression through its ubiquitination in a human gastric adenocarcinoma cell line, NUGC-3.2021

    • Author(s)
      K Moriwaki, Y Ueda, T Takeuchi, K Higuchi, and M Asahi.
    • Organizer
      第94回日本薬理学会
    • Data Source
      KAKENHI-PROJECT-19K07762
  • [Presentation] O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 oncogenic transcription factor to promote cancer progression.2020

    • Author(s)
      K Moriwaki, Y Ueda, K Higuchi, and M Asahi.
    • Organizer
      第93回日本薬理学会
    • Data Source
      KAKENHI-PROJECT-19K07762
  • [Presentation] Elevated O-GlcNAcylation increases FOXM1 protein via suppression of its poly-ubiquitination and subsequent proteasomal degradation.2019

    • Author(s)
      Y Ueda, K Moriwaki, N Sugawara, M Fukumoto, S Harada, K Ota, Y Kojima, T Takeuchi, K Higuchi, and M Asahi.
    • Organizer
      Digestive Disease Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07762
  • [Presentation] Elevated O-GlcNAcylation increases FOXM1 via suppression of FBXL2-mediated its poly-ubiquitination.2019

    • Author(s)
      Moriwaki K, Higuchi K, Asahi M.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K08678
  • [Presentation] Elevated O-GlcNAcylation increases FOXM1 protein via suppression of its poly-ubiquitination and subsequent proteasomal degradation.2019

    • Author(s)
      Ueda Y, Moriwaki K, Sugawara N, Fukumoto M, Harada S, Ota K, Kojima Y, Takeuchi T, Higuchi K, Asahi M.
    • Organizer
      Digestive Disease Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08678
  • [Presentation] O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 oncogenic transcription factor to promote cancer progression.2019

    • Author(s)
      Moriwaki K, Ueda Y, Higuchi K, Asahi M.
    • Organizer
      第93回日本薬理学会年
    • Data Source
      KAKENHI-PROJECT-17K08678
  • [Presentation] Elevated O-GlcNAcylation increases FOXM1 via suppression of FBXL2-mediated its poly-ubiquitination.2019

    • Author(s)
      K Moriwaki, K Higuchi, and M Asahi.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07762
  • 1.  朝日 通雄 (10397614)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 2.  HIRASHIMA Masanori (40383757)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  DING Guo (00514697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  竹内 利寿 (30445986)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  HIGUCHI Kazuhide
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  Inoue Takuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  Nakagawa Takatoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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