Asahi Michio 朝日通雄

… Alternative Names

Researcher Number	10397614
Other IDs
External Links
Affiliation (Current)	2022: 大阪医科薬科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021: 大阪医科薬科大学, 医学部, 教授 2008 – 2020: Osaka Medical College, 医学部, 教授 2013: 大阪医科大学, 薬理学, 教授 2007: Osaka University, 医学系研究科, 助教 2005 – 2006: 大阪大学, 医学系研究科, 助手
Review Section/Research Field	Principal Investigator Pathological medical chemistry / General medical chemistry / Basic Section 47040:Pharmacology-related Except Principal Investigator Urology / Circulatory organs internal medicine / Obstetrics and gynecology / Gastroenterology / Pathological medical chemistry / Basic Section 53010:Gastroenterology-related / Basic Section 47040:Pharmacology-related … More
Keywords	Principal Investigator 糖鎖 / ストレス / タンパク質 / 循環器・高血圧 / 筋小胞体タンパク質 / 循環器疾患 / 心筋小胞体 / 分子病態学 / 糖尿病 / O-GlcNAc修飾 … More Except Principal Investigator O-GlcNAc修飾 / 癌 / 心不全 / NF-κB / 糖鎖 / CD28-Superagonist / 非特異的免疫制御細胞 / Treg バンク / CD34+幹細胞 / ドナー特異的な免疫寛容 / MF-1遺伝子導入 / レンチウイルス / 超音波照射遺伝子導入法 / Tregバンク / 幹細胞共培養 / 免疫寛容 / CD28SA / カルシウム / チャネル / 心肥大 / カルモデュリン依存性キナーゼ / マイクロドメイン / シグナリング / カルシウムチャネル / プロテインキナーゼA / 細胞死 / EMT / 明細胞腺癌 / CD24 / MET / Met / 胃癌 / 大腸癌 / GSK3β / FBXL2 / ユビキチン化 / O-GlcNAc 修飾 / 糖尿病 / FOXM1 / TGF-3β / FOX-M1 / GSK-3β / 炎症性サイトカイン / p38 / 糖尿病合併癌 / コアフコース修飾 / 糖転移酵素 / ユビキチンリガーゼ / ホスホランバン / ヒトiPS細胞 / 分子標的治療薬 / 肝細胞 / がん / 薬剤起因性肝障害 / iPS細胞 / 遺伝子導入 / マイクロデバイス / 細胞 / 大気圧プラズマ / プラズマオンチップ / 癌微小環境 / 心リハ / 急性心筋梗塞　慢性心不全 / STIM1遺伝子 / SOCE Less

心不全の発症、病期進行に関与する無菌性炎症機構の解明と治療戦略の構築Principal Investigator
- Principal Investigator
  
  朝日通雄
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
O-GlcNAc修飾による癌微小環境制御機能の解析
- Principal Investigator
  
  森脇一将
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
STIM1に着目した心リハ効果の分子機構の解明と相乗効果が期待できる薬物の探索
- Principal Investigator
  
  永塚健宏
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Osaka Medical and Pharmaceutical University
糖転移酵素による糖尿病合併癌の制御メカニズムの解明と治療戦略の構築
- Principal Investigator
  
  樋口和秀
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Medical College
ユビキチンリガーゼParkinによる心筋収縮調節因子PLNの制御機構
- Principal Investigator
  
  横江俊一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical College
Elucidating Molecular Mechanisms of the Hepatotoxicity associated with Targeted Cancer Therapies
- Principal Investigator
  
  藤阪保仁
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Osaka Medical College
A gene delivery microdevice utilizing atmospheric pressure plasma targeting for single cells
- Principal Investigator
  
  熊谷慎也
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Meijo University
Role of TME O-GlcNAcylation in cancer proliferation
- Principal Investigator
  
  Moriwaki Kazumasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Medical College
Effect of elevated O-GlcNAc modification on onset of gastric and colon cancer
- Principal Investigator
  
  Higuchi Kazuhide
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka Medical College
Role of glycosylation on the functions of cardiac calcium regulating proteins and ion channelsPrincipal Investigator
- Principal Investigator
  
  Asahi Michio
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Medical College
Control of EMT phenomenon by mTOR inhiibitor for ovarian clear cell carcinoma.
- Principal Investigator
  
  TSUNETOH Satoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka Medical College
Regulation of L-type calcium channel by intracellular subunit in cardiac hypertrophy and failure.
- Principal Investigator
  
  NAKAYAMA HIROYUKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Functional analyses on the glycosylation in cardiac calcium-regulating proteins and ion channelsPrincipal Investigator
- Principal Investigator
  
  ASAHI Michio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Medical College
Novel approach of induction of donor specific immune tolerance: adoptive transfer of Treg cells combined with MF1 gene transfection
- Principal Investigator
  
  AZUMA Haruhito
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Osaka Medical College
The regulatory mechanism on cardiac SR proteins by O-linked N-acetyl glucosaminePrincipal Investigator
- Principal Investigator
  
  ASAHI Michio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Medical College
  Osaka University
Molecular mechanism of the regulating factors for sarcoplasmic reticulum Ca-ATPasePrincipal Investigator
- Principal Investigator
  
  ASAHI Michio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University

[Book] 酸化ストレスと心血管病2007
- Author(s)
  朝日通雄
- Publisher
  日本医学出版
- Data Source
  KAKENHI-PROJECT-19590306
[Book] The Lung Perspective2007
- Author(s)
  朝日通雄
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19590306
[Journal Article] O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 to induce cancer progression.2020
- Author(s)
  Y Ueda, K Moriwaki, T Takeuchi, K Higuchi, and M Asahi.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 521 Pages: 632-638
- DOI
  10.1016/j.bbrc.2019.10.164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07762, KAKENHI-PROJECT-17K08678
[Journal Article] Augmented <i>O</i>-GlcNAcylation alleviates inflammation-mediated colon carcinogenesis via suppression of acute inflammation2018
- Author(s)
  Hirata Y, Nakagawa T, Moriwaki K, Koubayashi E, Kakimoto K, Takeuchi T, Inoue T, Higuchi K, Asahi M
- Journal Title
  
  J. Clin. Biochem. Nutr.
  
  Volume: 3 Issue: 3 Pages: 221-229
- DOI
  10.3164/jcbn.17-106
- NAID
  130006730767
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08678, KAKENHI-PROJECT-16K09296
[Journal Article] Elevated O-GlcNAcylation stabilizes FOXM1 by its reduced degradation through GSK-3β inactivation in a human gastric carcinoma cell line, MKN45 cells.2018
- Author(s)
  Y. Inoue, K. Moriwaki, Y. Ueda, T. Takeuchi, K. Higuchi, M. Asahi
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 495(2) Pages: 1681-1687
- DOI
  10.1016/j.bbrc.2017.11.179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09296
[Journal Article] Caveolae-specific activation loop between CaMKII and L-type Ca2+ channel aggravates cardiac hypertrophy in α1-adrenergic stimulation.2017
- Author(s)
  Tonegawa K, Otsuka W, Kumagai S, Matsunami S, Hayamizu N, Tanaka S, Moriwaki K, Obana M, Maeda M, Asahi M, Kiyonari H, Fujio Y, Nakayama H.
- Journal Title
  
  Am J Physiol Heart Circ Physiol.
  
  Volume: 312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460397
[Journal Article] Augmented O-GlcNAcylation of AMP-activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line2017
- Author(s)
  Moriwaki K, Asahi M.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 15 Pages: 1287-1298
- DOI
  10.1158/1541-7786.mcr-16-0499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08678
[Journal Article] Adipose-derived stem cells exhibit high differentiation potential to cardiovascular cells in C57BL/6 mice.2016
- Author(s)
  Nagata, H., Ii, M.; Kohbayashi, E., Hoshiga, M., Hanafusa, T., Asahi, M.
- Journal Title
  
  Stem Cells Transl Med.
  
  Volume: 5 Pages: 141-151
- DOI
  10.5966/sctm.2015-0083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460397
[Journal Article] Degradation Is Induced by Phosphorylation-mediated Ubiquitination and Inhibited by Interaction with Cardiac Type Sarco(endo)plasmic Reticulum Ca2+-ATPase.,2016
- Author(s)
  Nakagawa, T., Yokoe, S., Asahi, M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 472 Pages: 523-30
- DOI
  10.1016/j.bbrc.2016.03.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460397
[Journal Article] rosstalk between PI3K and Ras pathways via protein phosphatase 2A in human ovarian clear cell carcinoma.2015
- Author(s)
  Takai M, Nakagawa T, Tanabe A, Terai Y, Ohmichi M, Asahi M.
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume: 16(2) Pages: 325-335
- DOI
  10.1080/15384047.2014.1002362
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460397, KAKENHI-PROJECT-25670709
[Journal Article] A vascular patch prepared from thai silk fibroin and gelatin hydrogel incorporating simvastatin-micelles to recruit endothelial progenitor cells.2015
- Author(s)
  Thitiwuthikiat P, Ii M, Saito T, Asahi M, Kanokpanont S, Tabata Y.
- Journal Title
  
  Tissue Eng Part A.
  
  Volume: 21(7-8) Pages: 1309-19
- DOI
  10.1089/ten.tea.2014.0237
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460397
[Journal Article] Sonic Hedgehog signaling regulates vascular differentiation and function in human CD34 positive cells: Vasculogenic CD34+ cells with Sonic Hedgehog.2015
- Author(s)
  Kanaya K, Masaaki I, Okazaki T, Nakamura T, Horii-Komatsu M, Alev C, Akimaru H, Kawamoto A, Akashi H, Tanaka H, Asahi M, Asahara T.
- Journal Title
  
  Stem Cell Res.
  
  Volume: 14(2) Pages: 165-176
- DOI
  10.1016/j.scr.2015.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460397, KAKENHI-PROJECT-25505009
[Journal Article] Genetic modulation of the SERCA activity does not affect the Ca(2+) leak from the cardiac sarcoplasmic reticulum.2014
- Author(s)
  Morimoto S, Hongo K, Kusakari Y, Komukai K, Kawai M, O-Uchi J, Nakayama H, Asahi M, Otsu K, Yoshimura M, Kurihara S.
- Journal Title
  
  Cell Calcium
  
  Volume: 55 Pages: 17-23
- DOI
  10.1016/j.ceca.2013.10.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390212, KAKENHI-PROJECT-23790255, KAKENHI-PUBLICLY-25136719, KAKENHI-PROJECT-25460397, KAKENHI-PROJECT-25670387
[Journal Article] Adipose-derived stromal cells inhibit prostate cancer cell proliferation inducing apoptosis2014
- Author(s)
  Takahara K, Ii M, Inamoto T, Komura K, Ibuki N, Minami K, Uehara H, Hirano H, Nomi H, Kiyama S, Asahi M, Azuma H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 446 Pages: 1102-7
- DOI
  10.1016/j.bbrc.2014.03.080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24791677, KAKENHI-PROJECT-25460397
[Journal Article] Clinical features and underlying causes of cerebral venous thrombosis in Japanese patients.2014
- Author(s)
  Shindo A, Wada H, Ishikawa H, Ito A, Asahi M, Ii Y, Ikejiri M, Tomimoto H.
- Journal Title
  
  Int J Hematol.
  
  Volume: 99(4) Pages: 437-40
- DOI
  10.1007/s12185-014-1550-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460397
[Journal Article] Induction of erythropoietin increases the cell proliferation rate in a hypoxia-inducible factor-1-dependent and -independent manner in renal cell carcinoma cell lines.2013
- Author(s)
  Fujisue Y, Nakagawa T, Takahara K, Inamoto T, Kiyama S, Azuma H, Asahi M.
- Journal Title
  
  Oncol Lett.
  
  Volume: 5 Pages: 1765-1770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390446
[Journal Article] Topical application of ex vivo expanded endothelial progenitor cells promotes vascularisation and wound healing in diabetic mice2013
- Author(s)
  Asai J
- Journal Title
  
  Int Wound J
  
  Volume: -- Pages: 527-33
- DOI
  10.1111/j.1742-481x.2012.01010.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590297, KAKENHI-PROJECT-23791286, KAKENHI-PROJECT-24591659, KAKENHI-PROJECT-25460397
[Journal Article] A Small Interfering RNA Targeting Lnk Accelerates Bone Fracture Healing with Early Neovascularization.2013
- Author(s)
  Kawakami Y, Ii M, Matsumoto T, Kawamoto A, Kuroda R, Akimaru H, Mifune Y, Shoji T, Fukui T, Asahi M, Kurosaka M, Asahara T.
- Journal Title
  
  Lab Invest
  
  Volume: 93 Pages: 1036-1053
- DOI
  10.1038/labinvest.2013.93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460397, KAKENHI-PROJECT-25462331, KAKENHI-PROJECT-25505009
[Journal Article] b1-Adrenergic Receptor Recycles Via a Membranous Organelle, Recycling Endosome, by Binding with Sorting Nexin272013
- Author(s)
  Takatoshi Nakagawa, Michio Asahi
- Journal Title
  
  J Membrane Biol
  
  Volume: 246 Pages: 571-579
- DOI
  10.1007/s00232-013-9571-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460397
[Journal Article] CXC-chemokine receptor 4 antagonist AMD3100 promotes cardiac functional recovery after ischemia/reperfusion injury via endothelial nitric oxide synthase-dependent mechanism.2013
- Author(s)
  Jujo K, Sekiguchi H, Klyachko E, Misener S, Tanaka T, Tongers J, Roncalli J, Renault MA, Thorne T, Ito A, Clarke T, Kamide C, Tsurumi Y, Hagiwara N, Qin G, Asahi M, Losordo DW
- Journal Title
  
  Circulation
  
  Volume: 127(1) Pages: 63-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590297
[Journal Article] Induction of erythropoietin increases the cell proliferation rate in a hypoxia‑inducible factor‑1‑dependent and ‑independent manner in renal cell carcinoma cell lines2013
- Author(s)
  Fujisue Y, Nakagawa T, Takahara K, Inamoto T, Kiyama S, Azuma H, Asahi M.
- Journal Title
  
  ONCOLOGY LETTERS
  
  Volume: 5 Pages: 1765-1770
- DOI
  10.3892/ol.2013.1283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460397
[Journal Article] Topical application of ex vivo expanded endothelial progenitor cells promotes vascularisation and wound healing in diabetic mice.2012
- Author(s)
  Asai J, Takenaka H, Ii M, Asahi M, Kishimoto S, Katoh N, Losordo DW
- Journal Title
  
  Int Wound J.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590297
[Journal Article] N-glycans of SREC-I (scavenger receptor expressed by endothelial cells): essential role for ligand binding, trafficking and stability2012
- Author(s)
  Sano M, , Korekane H, Ohtsubo K, Yamaguchi Y, Kato M, Shibukawa Y, Tajiri M, Adachi H, Wada Y, Asahi M, and Taniguchi N
- Journal Title
  
  Glycobiology
  
  Volume: 22(5) Pages: 714-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590297
[Journal Article] Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition2009
- Author(s)
  Schmitt JP, Ahmad F, Lorenz K, Hein L, Schulz S, Asahi M, Maclennan DH, Seidman CE, Seidman JG, Lohse MJ.
- Journal Title
  
  Circulation 119(3)
  
  Pages: 436-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590306
[Journal Article] N-glycan of ErbB family plays a crucialrole in dimer formation and tumor promotion2008
- Author(s)
  Takahashi M, Yokoe S, Asahi M, Lee SH, Li W, Osumi D, Miyoshi E, Taniguchi N
- Journal Title
  
  Biochim. Biophys. Acta 1780(3)
  
  Pages: 520-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590306
[Journal Article] Interaction sites among phospholamban, sarcolipin, and the sarco(endo)plasmic reticulum Ca^<2+>-ATPase2008
- Author(s)
  Morita T, Hussain D, Asahi M, Tsuda T, Kurzydlowski K, Toyoshima C, Maclennan DH
- Journal Title
  
  Biochem. Biophys. Res. Commun 369(1)
  
  Pages: 188-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590306
[Journal Article] Progression of heart failure was suppressed by inhibition of apoptosis signal-regulating kinase 1 via transcoronary gene transfer2007
- Author(s)
  Hikoso S, Ikeda Y, Yamaguchi O, Takeda T, Higuchi Y, Hirotani S, Kashiwase K, Yamada M, Asahi M, Matsumura Y, Nishida K, Matsuzaki M, Hori M, Otsu K.
- Journal Title
  
  J. Am. Coll. Cardiol 50
  
  Pages: 453-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590306
[Journal Article] A high expression of GDP-fucose transporter in hepatocellular carcinoma is a key factor for in creases in fucosylation2007
- Author(s)
  Moriwaki K, Noda K, Nakagawa T, Asahi M, Yoshihara H, Taniguchi N, Hayashi N, Miyoshi E
- Journal Title
  
  Glycobiology 17
  
  Pages: 131-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590306
[Journal Article] The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress2007
- Author(s)
  Nakai A, Yamaguchi O, Takeda T, Higuchi Y, Hikoso S, Taniike M, Omiya S, Mizote I, Matsumura Y, Asahi M, Nishida K, Hori M, Mizushima N, Otsu K.
- Journal Title
  
  Nature Med 13
  
  Pages: 619-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590306
[Journal Article] The Asn^<418>-linked N-glycan of ErbB3 plays a crucial role in preventing spontaneous heterodimerization and tumor promotion.2007
- Author(s)
  Shunichi Yokoe, Motoko Takahashi, Michio Asahi, Seung Ho Lee, Wei Li, Daisuke Osumi, Eiji Miyoshi, Naoyuki Taniguchi
- Journal Title
  
  Cancer Research (in press)
- Data Source
  KAKENHI-PROJECT-17590249
[Journal Article] Identification of an inducible factor secreted by pancreatic cancer cell lines that stimulates the production of fucosylated haptoglobin in hepatoma cells2006
- Author(s)
  Narisada M, Kawamoto S, Kuwamoto K, Moriwaki K, Nakagawa T, Matsumoto H, Asahi M, Koyama N, Miyoshi E.
- Journal Title
  
  Biochem Biophys Res Commun 377(3)
  
  Pages: 792-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590306
[Journal Article] スーパーオキシドジスムターゼとグルタチオンペルオキシダーゼ2006
- Author(s)
  朝日通雄, 谷口直之
- Journal Title
  
  酸化ストレスと心血管疾患-分子機構の解明から治療への応用まで Vol.218(1)
  
  Pages: 19-23
- Data Source
  KAKENHI-PROJECT-17590249
[Journal Article] 活性酸素種のアポトーシスにおける役割2006
- Author(s)
  朝日通雄, 朴用用軾, 谷口直之
- Journal Title
  
  酸化ストレス-フリーラジカル医学生物学の最前線 Ver.2
  
  Pages: 111-115
- Data Source
  KAKENHI-PROJECT-17590249
[Presentation] Gene expression changes in iPS cellscaused by non-thermal atmospheric pressure plasma irradiations2021
- Author(s)
  Mime Kobayashi, Kiichiro Tomoda, Tetsuji Shimizu, Michio Asahi, Shinya Kumagai
- Organizer
  13th International Symposium on Advanced Plasma Science and its Applications for Nitrides and Nanomaterials 14th International Conference on Plasma-Nano Technology & Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04457
[Presentation] 大気圧プラズマがiPS細胞分化に与える影響の解析2021
- Author(s)
  小林未明、友田紀一郎、清水鉄司、朝日通雄、熊谷慎也
- Organizer
  第68回応用物理学会春季学術講演会
- Data Source
  KAKENHI-PROJECT-19H04457
[Presentation] Effects of non-thermal atmospheric pressure plasma on iPS cell differentiation2020
- Author(s)
  Mime Kobayashi, Kiichiro Tomoda, Michio Asahi, Shinya Kumagai
- Organizer
  The 67th JSAP Spring Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04457
[Presentation] 心不全において、ホスホランバンはParkinによる分解を受けている2020
- Author(s)
  横江俊一、朝日通雄
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07130
[Presentation] Elevated O-GlcNAcylation increases FOXM1 protein via suppression of its poly-ubiquitination and subsequent proteasomal degradation.2019
- Author(s)
  Ueda Y, Moriwaki K, Sugawara N, Fukumoto M, Harada S, Ota K, Kojima Y, Takeuchi T, Higuchi K, Asahi M.
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08678
[Presentation] Effects of non-thermal atmospheric pressure plasma on iPS cell differentiation2019
- Author(s)
  Mime Kobayashi, Kiichiro Tomoda, Michio Asahi, Shinya Kumagai
- Organizer
  CiRA 2019 International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04457
[Presentation] O-GlcNAcylation stabilizes FOXM1protein Via suppression-of its poly-ubquitination2019
- Author(s)
  Kazumasa　Moriwaki，Yasuhiro　Ueda，Kazuhide　Higuchi，and Michio Asahi
- Organizer
  第92回　日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K09296
[Presentation] Low temperature plasma for controlling iPS cell differentiation2019
- Author(s)
  Mime Kobayashi, Kiichiro Tomoda, Michio Asahi, Shinya Kumagai
- Organizer
  The 72nd Annual Gaseous Electronics Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04457
[Presentation] Elevated O-GlcNAcylation increases FOXM1 via suppression of FBXL2-mediated its poly-ubiquitination.2019
- Author(s)
  Moriwaki K, Higuchi K, Asahi M.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08678
[Presentation] ヒトiPS細胞を用いたゲフィチニブ起因性肝障害のin vitroモデルの樹立とメカニズム解析2019
- Author(s)
  朝日通雄（大阪医大・医・薬理）、友田紀一郎（大阪医大・医・薬理）、渡辺満里奈（大阪医大・医・薬理）、藤阪保仁（大阪医大・医・臨床研究センター）
- Organizer
  日本臨床薬理学会
- Data Source
  KAKENHI-PROJECT-19K07179
[Presentation] O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 oncogenic transcription factor to promote cancer progression.2019
- Author(s)
  Moriwaki K, Ueda Y, Higuchi K, Asahi M.
- Organizer
  第93回日本薬理学会年
- Data Source
  KAKENHI-PROJECT-17K08678
[Presentation] Elevated O-GlcNAcylation stabilizes FoxM1 protein via suppression of its proteasomal degradation2018
- Author(s)
  Kazumasa Moriwaki, Yasuhiro Ueda, Kazuhide Higuchi, and Michio Asahi
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09296
[Presentation] Phospholamban is degraded via ubiquitin-proteasome pathway by pVHL in failing hearts2017
- Author(s)
  横江俊一,　朝日通雄
- Organizer
  日本薬理学会学術総会
- Place of Presentation
  長崎ブリックホール、他
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] O－GlcNAcylation promotes cell proliferation through the increase of FoxM1 expression in gastric cancer cells2017
- Author(s)
  森脇一将,　井上陽介,　樋口和秀,　朝日通雄
- Organizer
  日本薬理学会学術総会
- Place of Presentation
  長崎ブリックホール、他
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K09296
[Presentation] O－GlcNAcylation of GSK-3β exacerbates pressure overload-induced heart failure in OGT transgenic mice2017
- Author(s)
  松野真人,　横江俊一,　伊井正明,　朝日通雄
- Organizer
  日本薬理学会学術総会
- Place of Presentation
  長崎ブリックホール、他
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] O-GlcNAc糖鎖修飾の上昇は転写因子FOXM1の分解を阻害することで癌細胞の増殖を促進する2017
- Author(s)
  森脇一将, 井上陽介, 上田康裕, 樋口和秀, 朝日通雄
- Organizer
  2017年度生命科学系学会合同年次大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09296
[Presentation] Augmented O-GlcNAcylation Alleviates Inflammation-mediated Colon Carcinogenesis via Suppression of Acute Inflammation2017
- Author(s)
  中川孝俊,　平田好正,　森脇一将,　光林栄子,　柿本一誠,　竹内利久,　井上拓也,　樋口和秀,　朝日通雄
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K09296
[Presentation] Phospholamban is located in autophagosome in dilated cardiomyopathy mouse model, TgPLNR9C mice2016
- Author(s)
  Yokoe,S, MacLennan,DH, Asahi,M
- Organizer
  Experimental Biology
- Place of Presentation
  San Diego
- Year and Date
  2016-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] 心不全モデルマウス(TgPLNR9Cmice)の心臓においてホスホランバンはオートファジーで分解される」2016
- Author(s)
  Yokoe,S, MacLennan,DH, Asahi,M
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] The role of protein O-GlcNAcylation in colonic inflammatory carcinogenesis.2016
- Author(s)
  平田好正, 井上拓也, 柿本一城, 江戸川祥子, 岡田俊彦, 竹内利寿, 中川孝俊, 朝日通雄
- Organizer
  DDW2016
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09296
[Presentation] Phospholamban is localized in autophagosome in dilated cardiomyopathy mouse model, TgPLNR9C mice2016
- Author(s)
  Shunichi yokoe, David H.MacLennan, Michio Asahi
- Organizer
  EB San Diego2016
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2016-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] Relationship Between Gastric Cancer and O-GlcNacylation2016
- Author(s)
  Yosuke Inoue, Kazumasa Moriwaki, Kazuhide Higuchi, and Michio Asahi
- Organizer
  DDW2016
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09296
[Presentation] Crosstalk between O-GlcNAcylation and Phosphorylation Regulates Autophagy in Diabetes Mellitus and OGT-Tg Mice Exposed to Intermittent Hypoxia2015
- Author(s)
  野田拓誠、野村篤生、吉村文、加藤隆児、井尻好雄、山口雄大、泉康雄、葭山実、朝日通雄、林哲也
- Organizer
  日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場（グランキューブ大阪）
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] Cross talk between PI3K and Ras pathways via protein phosphatase 2A in human ovarian clear cell carcinoma2015
- Author(s)
  高井雅聡、中川孝俊、田辺晃子、寺井義人、大道正英、朝日通雄
- Organizer
  日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] O-Linked N-Acetyl Glucosamine (O-GlcNAc) Regulates Autophagy and Apoptosis in Cardiomyocytes: a Double-Edged Sword in Intermittent Hypoxia-Induced Cardiac Remodeling2014
- Author(s)
  中川孝俊,佐々木泉帆、渡辺明、古川裕一、野村篤生、上橋和佳、加藤隆児、井尻好雄、林哲也、朝日通雄
- Organizer
  日本生化学会近畿支部例会
- Place of Presentation
  京都産業大学
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] Generation of an inhibitory antibody against claudin- 15 for modulation of intestinal epithelial barrier function2014
- Author(s)
  森脇一将、朝日通雄、古瀬幹夫
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] アドレナリン受容体のリサイクルはソーティングネキシン27に依存しリサイクリングエンドソームを経由している2013
- Author(s)
  中川孝俊、朝日通雄
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22590297
[Presentation] Local/controlled-release statin ameliorates adipose- derived stem cell therapy in limb ischemia2013
- Author(s)
  Shintani, T, Ii M, Asahi, M, Saito, T, Tabata, Y
- Organizer
  14th Congress of Asian Society for Vascular Surgery
- Place of Presentation
  トルコ　イスタンブール
- Data Source
  KAKENHI-PROJECT-25460397
[Presentation] ラット小腸上皮細胞IEC-6 における lansoprazole による HO-1 発現誘導分子機構の検討2012
- Author(s)
  依田有紀子, 中川孝俊、朝日通雄
- Organizer
  第59回日本生化学会近畿支部例会
- Place of Presentation
  京都大学宇治おうばくプラザ
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-22590297
[Presentation] HO-1 発現誘導を介したインドメタシン起因性小腸粘膜傷害の抑制機序2012
- Author(s)
  原田智、梅垣英次、朝日通雄、樋口和秀
- Organizer
  第31回消化器病態生理勉強会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2012-07-28
- Data Source
  KAKENHI-PROJECT-22590297
[Presentation] ホスホランバンのO-GlcNAc修飾が糖尿病性心筋症へ及ぼす影響について2008
- Author(s)
  横江俊一、藤原範子、江口裕伸、崎山晴彦、吉原大作、朝日通雄、谷口直之、鈴木敬一郎
- Organizer
  日本メーラード学会
- Place of Presentation
  東京
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19590306
[Presentation] Abnormality of Glutathione Metabolism in Fut8 Null-mice : Implications for Their Newborn Death2007
- Author(s)
  Mizuno Y, Asahi M, Misumi Y, Yamauchi M, Sano M, Taniguchi N, Miyoshi E
- Organizer
  札幌癌セミナー
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-19590306
[Presentation] O-GlcNAcylation of phospholamban induces cardiac dysfunction2007
- Author(s)
  Yokoe S, Asahi M, Suzuki K, Taniguchi N, Miyoshi E
- Organizer
  Glycobiology2007
- Place of Presentation
  Boston
- Year and Date
  2007-11-13
- Data Source
  KAKENHI-PROJECT-19590306
[Presentation] O-GlcNAcylation of phospholamban induces cardiac dysfunction2007
- Author(s)
  Yokoe S, Asahi M, Suzuki K, Taniguchi N, Miyoshi E
- Organizer
  日本生化学会
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19590306
[Presentation] Abnormality of Glutathione Metabolism in Fut8 Null-mice2007
- Author(s)
  Mizuno Y, Asahi M, Misumi Y, Yamauchi M, Sano M, Wang X, Taniguchi N, Miyoshi E
- Organizer
  Implic ations for Their Newborn Death
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19590306
[Presentation] 腸管上皮細胞のバリア機能を調節する機能阻害抗体の作製
- Author(s)
  森脇一将、朝日通雄、月田承一郎、古瀬幹夫
- Organizer
  第60回日本生化学会近畿支部例会
- Place of Presentation
  大阪大学吹田キャンパス
- Data Source
  KAKENHI-PROJECT-25460397

1. Moriwaki Kazumasa (00467656)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
2. AZUMA Haruhito (40231914)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. NAKAYAMA HIROYUKI (40581062)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. Higuchi Kazuhide (20218697)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. 横江俊一 (40454756)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 友田紀一郎 (50362843)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. Nakagawa Takatoshi

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. ISAKA Yoshitaka (00379166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. LI Xiaokang (60321890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKAHARA Siro (70179547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. FUJIO Yasushi (20359839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUNETOH Satoshi (70388255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TANAKA Yoshimichi (10625502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HAYASHI Masami (00551748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KANEMURA Masanori (40298782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TANABE Akiko (70454543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. TERAI Yoshito (90278531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. YAMADA Takashi (10182536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OHMICHI Masahide (10283764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 勝岡洋治 (10051757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 三善英知 (20322183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 藤阪保仁 (50411369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 熊谷慎也 (70333888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
24. 清水鉄司 (70803881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. 小林未明 (60393807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 永塚健宏 (10860083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Ii Masaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
28. Ai Tomohiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
29. Takeuchi Toshihisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
30. Inoue Takuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
31. INAMOTO Teruo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. ASAI Jun

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. KURODA Ryosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. KUROSAKA Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. MATSUMOTO Tomiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 森本智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 草刈洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 高原史郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 加藤則人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 浅原孝之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
41. 秋丸裕司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
42. 川本篤彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Asahi Michio 朝日 通雄

ASAHI Michio 朝日 通雄

Research Projects

Research Products

Co-Researchers

心不全の発症、病期進行に関与する無菌性炎症機構の解明と治療戦略の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of glycosylation on the functions of cardiac calcium regulating proteins and ion channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analyses on the glycosylation in cardiac calcium-regulating proteins and ion channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulatory mechanism on cardiac SR proteins by O-linked N-acetyl glucosaminePrincipal Investigator

Principal Investigator

Asahi Michio 朝日通雄

ASAHI Michio 朝日通雄