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Hasegawa Junya  長谷川 純矢

… Alternative Names

HASEGAWA Junya  長谷川 純矢

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Researcher Number 00533788
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-1216-7468
Affiliation (Current) 2026: 北里大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help 2024: 北里大学, 薬学部, 講師
2019 – 2023: 東京医科歯科大学, 難治疾患研究所, 助教
2015: 大阪大学, 大学院生命機能研究科, 助教
2012 – 2015: 大阪大学, 生命機能研究科, 助教
Review Section/Research Field
Principal Investigator
Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Structural biochemistry / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 43030:Functional biochemistry-related
Except Principal Investigator
Functional biochemistry
Keywords
Principal Investigator
質量分析 / リン脂質 / イノシトールリン脂質 / 脂肪酸 / 老化 / Gタンパク質共役受容体 / すい臓がん / GPCR / リゾリン脂質 / リソソーム … More / 脂質 / オートファジー / EGF / Multivesicular body / SH3ドメイン / エンドサイトーシス … More
Except Principal Investigator
F-Barドメイン / 脂質結合蛋白質 / PIP3 ホスファターゼ / 膜変形 / インスリン シグナル / PI4P / Sac1 / SKIP / インスリン / ホスホイノシタイド 5-ホスファターゼ / 脂質結合タンパク質 / 膜形成 / がん細胞転移 / インスリンシグナル / 膜の形 / ホスホイノシタイド Less
  • Research Projects

    (7 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (13 People)
  •  リン脂質から迫る老化誘導マシナリーの解明Principal Investigator

    • Principal Investigator
      長谷川 純矢
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Kitasato University
  •  Comprehensive search for novel phospholipids and elucidation of their functionsPrincipal Investigator

    • Principal Investigator
      Hasegawa Junya
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  A study of novel lysophospholipids and exploration of their targetsPrincipal Investigator

    • Principal Investigator
      Hasegawa Junya
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Identification of novel molecules on lysosomal membrane using our unique techniquePrincipal Investigator

    • Principal Investigator
      Hasegawa Junya
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  The development of method for the isolation of autophagosomesPrincipal Investigator

    • Principal Investigator
      Hasegawa Junya
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Structural biochemistry
    • Research Institution
      Osaka University
  •  Analysis of the role of SH3YL1 in the morphology of plasma membrane and endocytosis machineryPrincipal Investigator

    • Principal Investigator
      HASEGAWA Junya
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Osaka University
  •  Regulation of cell dynamism by phosphoinositides

    • Principal Investigator
      Takenawa Tadaomi
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University

All 2024 2023 2022 2021 2019 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book Other

  • [Book] Thr Lipid2021

    • Author(s)
      長谷川 純矢
    • Total Pages
      7
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-20H03206
  • [Book] 哺乳動物個体レベルでのオートファジーの意義と疾患とのかかわり, ファルマシア49 (6)2013

    • Author(s)
      長谷川純矢、吉森保
    • Data Source
      KAKENHI-PROJECT-24770098
  • [Journal Article] New insights into the regulation and roles of phosphatidylinositol 3,4-bisphosphate2024

    • Author(s)
      Hasegawa Junya
    • Journal Title

      The Journal of Biochemistry

      Volume: 176 Issue: 5 Pages: 339-345

    • DOI

      10.1093/jb/mvae063

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24K02176
  • [Journal Article] Definition of phosphatidylinositol 4,5-bisphosphate distribution by freeze-fracture replica labeling2024

    • Author(s)
      Tsuji Takuma、Hasegawa Junya、Sasaki Takehiko、Fujimoto Toyoshi
    • Journal Title

      Journal of Cell Biology

      Volume: 224 Issue: 1

    • DOI

      10.1083/jcb.202311067

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06818, KAKENHI-PROJECT-23K27319, KAKENHI-PROJECT-24K02176, KAKENHI-PROJECT-22H00446
  • [Journal Article] p53 ensures the normal behavior and modification of G1/S-specific histone H3.1 in the nucleus2024

    • Author(s)
      Oikawa Tsukasa、Hasegawa Junya、Handa Haruka、Ohnishi Naomi、Onodera Yasuhito、Hashimoto Ari、Sasaki Junko、Sasaki Takehiko、Ueda Koji、Sabe Hisataka
    • Journal Title

      Life Science Alliance

      Volume: 7 Issue: 9 Pages: e202402835-e202402835

    • DOI

      10.26508/lsa.202402835

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-23K21392, KAKENHI-PROJECT-23K27319, KAKENHI-PROJECT-24K02176, KAKENHI-PROJECT-24K02220, KAKENHI-PROJECT-24K09447
  • [Journal Article] Attenuated cerebellar phenotypes in Inpp4a truncation mutants with preserved phosphatase activity.2023

    • Author(s)
      Tran DM, Yoshioka N, Bizen N, Mori-Ochiai Y, Yano M, Yanai S, Hasegawa J, Miyashita S, Hoshino M, Sasaki J, Sasaki T, Takebayashi H
    • Journal Title

      Dis Model Mech

      Volume: 16 Issue: 7 Pages: 192-206

    • DOI

      10.1242/dmm.050169

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K15912, KAKENHI-PROJECT-23K14295, KAKENHI-PROJECT-23K06300, KAKENHI-PROJECT-23K06317, KAKENHI-PROJECT-22K19287, KAKENHI-PROJECT-19H03543, KAKENHI-PROJECT-21H02652, KAKENHI-PUBLICLY-22H05589, KAKENHI-PROJECT-20H00485, KAKENHI-PROJECT-21H02680, KAKENHI-PROJECT-23K23993, KAKENHI-PROJECT-23K27319
  • [Journal Article] Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration2023

    • Author(s)
      Benyair Ron、Panapakkam Giridharan Sai Srinivas、Rivero-R?os Pilar、Hasegawa Junya、Bristow Emily、Eskelinen Eeva-Liisa、Shmueli Merav D、Fishbain-Yoskovitz Vered、Merbl Yifat、Sharkey Lisa M、Paulson Henry L.、Hanson Phyllis I、Patnaik Samarjit、Al-Ramahi Ismael、Botas Juan、Marugan Juan、Weisman Lois S.
    • Journal Title

      Autophagy Reports

      Volume: 2 Issue: 1 Pages: 2166722-2166722

    • DOI

      10.1080/27694127.2023.2166722

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03206, KAKENHI-PROJECT-22K19287
  • [Journal Article] A mass spectrometric method for in-depth profiling of phosphoinositide regioisomers and their diseaseassociated regulation.2022

    • Author(s)
      Morioka S, Nakanishi H, Yamamoto T, Hasegawa J, Tokuda E, Hikita T, Sakihara T, Kugii Y, Oneyama C, Yamazaki M, Suzuki A, Sasaki J, Sasaki T.
    • Journal Title

      Nature Communications

      Volume: 13(1) Issue: 1 Pages: 83-83

    • DOI

      10.1038/s41467-021-27648-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04905, KAKENHI-PUBLICLY-20H04920, KAKENHI-PROJECT-20H03456, KAKENHI-PROJECT-21H02680, KAKENHI-PROJECT-20J40228, KAKENHI-PROJECT-21K19329, KAKENHI-PROJECT-22K19287, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04806, KAKENHI-PROJECT-20H03206, KAKENHI-PROJECT-20K20661
  • [Journal Article] PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity2022

    • Author(s)
      Hasegawa Junya、Tokuda Emi、Yao Yao、Sasaki Takehiko、Inoki Ken、Weisman Lois S.
    • Journal Title

      Molecular Biology of the Cell

      Volume: 33 Issue: 3

    • DOI

      10.1091/mbc.e21-06-0309

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20J40228, KAKENHI-PROJECT-21K19329, KAKENHI-PROJECT-22K19287, KAKENHI-PROJECT-20H03206
  • [Journal Article] A Role of Phosphatidylserine in the Function of Recycling Endosomes2021

    • Author(s)
      Hasegawa Junya、Uchida Yasunori、Mukai Kojiro、Lee Shoken、Matsudaira Tatsuyuki、Taguchi Tomohiko
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 9 Pages: 783857-783857

    • DOI

      10.3389/fcell.2021.783857

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H05307, KAKENHI-PROJECT-20H03202, KAKENHI-PROJECT-20H03206, KAKENHI-PROJECT-21K06153, KAKENHI-PROJECT-17H06164, KAKENHI-PLANNED-17H06418
  • [Journal Article] SH3YL1 cooperates with ESCRT-I in the sorting and degradation of the EGF receptor2019

    • Author(s)
      Hasegawa Junya、Jebri Imen、Yamamoto Hikaru、Tsujita Kazuya、Tokuda Emi、Shibata Hideki、Maki Masatoshi、Itoh Toshiki
    • Journal Title

      Journal of Cell Science

      Volume: 132 Issue: 19 Pages: 229179-229179

    • DOI

      10.1242/jcs.229179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06541, KAKENHI-PROJECT-19K06638, KAKENHI-PROJECT-19K22275, KAKENHI-PROJECT-19K22381, KAKENHI-PROJECT-16H04785
  • [Journal Article] Selective autophagy: Lysophagy2015

    • Author(s)
      Hasegawa J, Maejima I, Iwamoto R, Yoshimori T
    • Journal Title

      Methods

      Volume: 75 Pages: 128-132

    • DOI

      10.1016/j.ymeth.2014.12.014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26650019, KAKENHI-ORGANIZER-25111001
  • [Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion and invasive cell migration in human breast cancer2014

    • Author(s)
      Tokuda E, Itoh T, Hasegawa J, Ijuin T, Takeuchi Y, Irino Y, Fukumoto M, Takenawa T.
    • Journal Title

      Cancer Research

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24770098
  • [Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion, cell migration and invasion in human breast cancer2014

    • Author(s)
      Tokuda E., Itoh T., Hasegawa J., Ijuin T., Takeuchi Y., Irino, Y., Fukumoto M., and Takenawa T.
    • Journal Title

      Cancer Res. 74, 3054-3066 (2014)

      Volume: 74 Pages: 3054-3066

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23227005
  • [Journal Article] Antagonistic regulation of F-BAR protein assemblies controls actin polymerization during podosome formation2014

    • Author(s)
      Tsujita K, Kondo A, Kurisu S, Hasegawa J, Itoh T, Takenawa T
    • Journal Title

      J Cell Sci

      Volume: 126 Pages: 2267-2278

    • Data Source
      KAKENHI-PROJECT-24770098
  • [Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion, and invasive cell migration in human breast cancer2014

    • Author(s)
      Tokuda E., Itoh T., Hasegawa J., Ijuin T., Takeuchi Y., Irino, Y., Fukumoto M., and Takenawa T.
    • Journal Title

      Cancer Res.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23227005
  • [Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion and invasive cell migration in human breast cancer2014

    • Author(s)
      Tokuda E, Itoh T, Hasegawa J, Ijuin T, Takeuchi Y, Irino Y, Fukumoto M, Takenawa T
    • Journal Title

      Cancer Res

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-24770098
  • [Journal Article] Mechanistic insights into the regulation of circular dorsal ruffle formation.2013

    • Author(s)
      Itoh T, Hasegawa J.
    • Journal Title

      J Biochem.

      Volume: 153 Issue: 1 Pages: 21-29

    • DOI

      10.1093/jb/mvs138

    • NAID

      40019546440

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24570216, KAKENHI-PROJECT-24770098, KAKENHI-PUBLICLY-24113715
  • [Journal Article] Antagonistic regulation of F-BAR protein assemblies controls actin polymerization during podosome formation.2013

    • Author(s)
      Tsujita K, Kondo A, Kurisu S, Hasegawa J, Itoh T, Takenawa T.
    • Journal Title

      J. Cell Sci.

      Volume: 126 Pages: 2267-2278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23227005
  • [Journal Article] Antagonistic regulation of F-BAR protein assemblies controls actin polymerization during podosome formation.2013

    • Author(s)
      Tsujita K, Kondo A, Kurisu S, Hasegawa J, Itoh T, Takenawa T.
    • Journal Title

      J Cell Sci.

      Volume: 126 Pages: 2267-2278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24770098
  • [Journal Article] Mechanistic insights into the regulation of circular dorsal ruffle formation2013

    • Author(s)
      Itoh T, Hasegawa J
    • Journal Title

      J Biochem

      Volume: 153 Pages: 21-29

    • NAID

      40019546440

    • Data Source
      KAKENHI-PROJECT-24770098
  • [Journal Article] ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf52012

    • Author(s)
      Hasegawa J
    • Journal Title

      Mol. Biol. Cell

      Volume: 23 Issue: 13 Pages: 2481-2489

    • DOI

      10.1091/mbc.e12-01-0017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23227005, KAKENHI-PROJECT-23770228, KAKENHI-PROJECT-24570216, KAKENHI-PROJECT-24770098, KAKENHI-PUBLICLY-24113715
  • [Journal Article] Qu antification and visualization of phosphoinositides by quantum dot-labeled specific binding-domain probes2012

    • Author(s)
      Irino Y, Tokuda E, Hasegawa J, Itoh T, Takenawa T
    • Journal Title

      J Lipid Res

      Volume: 53 Pages: 810-819

    • Data Source
      KAKENHI-PROJECT-24770098
  • [Journal Article] Quantification and visualization of phosphoinositides by quantum dot-labeled specific binding-domain probes2012

    • Author(s)
      Irino Y, Tokuda E, Hasegawa J, Itoh T, Takenawa T
    • Journal Title

      J.Lipid.Res.

      Volume: (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23227005
  • [Journal Article] A RAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf52012

    • Author(s)
      Hasegawa J, Tsujita K, Takenawa T, Itoh T
    • Journal Title

      Mol Biol Cell

      Volume: 23 Pages: 2481-2489

    • Data Source
      KAKENHI-PROJECT-24770098
  • [Journal Article] SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain2011

    • Author(s)
      Hasegawa J, Tbkuda E, Tenno T, Isujita K, Sawai H, Hiroaki H, Takenawa T, Itoh T
    • Journal Title

      J.Cell Biol.

      Volume: 193 Pages: 901-916

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23227005
  • [Presentation] イノシトールリン脂質が制御する老化メカニズムの解明2023

    • Author(s)
      長谷川純矢、佐々木純子、佐々木雄彦
    • Organizer
      第65回日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-22K19287
  • [Presentation] A new insights into the roles of phosphoinositides in lysosomal function2021

    • Author(s)
      Junya Hasegawa, Lois S. Weisman, Junko Sasaki, Takehiko Sasaki
    • Organizer
      第44回日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03206
  • [Presentation] Inositol polyphosphate-5-phosphatase INPP5E regulates autophagy in neural cells2014

    • Author(s)
      Hasegawa Junya
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Austin, Texas, USA
    • Data Source
      KAKENHI-PROJECT-24770098
  • [Presentation] Inositol polyphosphate-5-phosphatase INPP5E regulates autophagy in neural cells

    • Author(s)
      Junya Hasegawa, Tamotsu Yoshimori
    • Organizer
      Keystone Symposia (Autophagy: Fundamentals to Disease)
    • Place of Presentation
      Hyatt Regency Austin, Austin, Texas, USA
    • Year and Date
      2014-05-23 – 2014-05-28
    • Data Source
      KAKENHI-PROJECT-26650019
  • [Presentation] Inositol polyphosphate-5-phosphatase INPP5E regulates autophagy in neural cells

    • Author(s)
      Junya Hasegawa, Tamotsu Yoshimori
    • Organizer
      第66回日本細胞生物学会大会
    • Place of Presentation
      奈良県新公会堂
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-26650019
  • []

  • []

  • 1.  Takenawa Tadaomi (40101315)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 2.  ITOH Toshiki (30313092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  IJUIN Takeshi (00361626)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  TSUJITA Kazuya (10457054)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  TOKUDA Emi (70621960)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  IRINO Yasuhiro (10415565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  井上 飛鳥 (50525813)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  吉岡 望
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  鈴木 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  向井 康治朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  辻 琢磨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  伊佐 正
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  青木 茂樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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