IRINO Yasuhiro 入野康宏

… Alternative Names

入野康宏イリノヤスヒロ

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Researcher Number	10415565
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2021: 神戸大学, 医学研究科, 医学研究員 2016 – 2018: 神戸大学, 医学研究科, 特命助教 2015: 神戸大学, 医学(系)研究科(研究院), 特命助教 2015: 神戸大学, 医学研究科, 助教 2015: 神戸大学, 大学院医学研究科, 特任助教 … More 2012 – 2015: 神戸大学, 医学(系)研究科(研究院), 助教 2013: 神戸大学, 医学(系)研究科(研究院), 特命助教 2008: 国立精神・神経センター, 神経研究所・代謝研究部, 研究員 2006: 国立精神・神経センター, 神経研究所代謝研究部, 研究員 2006: 国立精神・神経センター, 神経研究所代謝研究部, 研究員 2005: 国立精神・神経センター, 研究員 Less
Review Section/Research Field	Principal Investigator Tumor biology / Basic Section 53020:Cardiology-related / Tumor diagnosis Except Principal Investigator Basic Section 53020:Cardiology-related / Functional biochemistry / Neurosurgery / Food science / Neurochemistry/Neuropharmacology / Biological Sciences
Keywords	Principal Investigator 代謝 / がん / メタボローム解析 / 高密度リポタンパク質 / 高比重リポタンパク質 / 癌 / グルタミノリシス / がん細胞の特性 / グルタミンデヒドロゲナーゼ / アンモニア … More / グルタミン代謝 / がんの代謝 / 上皮間葉転換 / バイオマーカー / メタボロミクス … More Except Principal Investigator ATP / ミクログリア / 高密度リポタンパク質 / 高比重リポタンパク質 / がん / フィブロネクチン / 高比重リポ蛋白（HDL) / 高比重リポたんぱく質（HDL） / F-Barドメイン / 脂質結合蛋白質 / PIP3 ホスファターゼ / 膜変形 / インスリン　シグナル / PI4P / Sac1 / SKIP / インスリン / ホスホイノシタイド　５－ホスファターゼ / 脂質結合タンパク質 / 膜形成 / がん細胞転移 / インスリンシグナル / 膜の形 / ホスホイノシタイド / ｍTOR / グリオーマ / mTOR / グルタミナーゼ / グルタミン代謝 / 抗がん活性 / 栄養素 / 食品成分 / 化学的ノックアウト解析 / フェルラ酸シクロアルテニル / 米糠 / RNA干渉 / メタボローム解析 / ナフトキノン / クルクミン / 抗アレルギー活性 / 抗炎症活性 / ステロール配糖体エステル / β-マンゴスチン / 作用機序 / ノックダウン解析 / マイクロアレイ解析 / 抗がん作用 / 抗炎症作用 / 酵素阻害剤 / DNA合成酵素 / 健康機能性食品 / 脳・神経 / PLC / 細胞遊走 / インテグリン / 細胞外ヌクレオチド / シグナル伝達 / 細胞運動 / グルタミン酸 / カルシウム / NMDA受容体 / ATP受容体 / ニューロン / 可視化 / トランスジェニックマウス / EGFP / Iba1 / マクロファージ / 膜ラッフル / 遊走能 / P2X4受容体 / P2Y12受容体 / ケモタキシス Less

Elucidation of the interaction between cells and HDL with multifaceted actionsPrincipal Investigator
- Principal Investigator
  
  Irino Yasuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
Elucidating molecular mechanisms of HDL functionality
- Principal Investigator
  
  Ishida Taturo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
Understanding of glutamine metabolism in cancer cellsPrincipal Investigator
- Principal Investigator
  
  Irino Yaushiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kobe University
Integrated analyses of GBM cell lines, in vivo xenograft models, and clinical samples to examine the glutamine metabolism in response to mTOR-targeted treatments
- Principal Investigator
  
  TANAKA KAZUHIRO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kobe University
Understanding metabolic regulation of epithelial-mesenchymal transitionPrincipal Investigator
- Principal Investigator
  
  Irino Yasuhiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kobe University
Screening of DNA polymerase species selective inhibitors from nutrients and food components, and analysis of novel healthy functions
- Principal Investigator
  
  MIZUSHINA Yoshiyuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shinshu University
  Kobe Gakuin University
Comprehensive metabolome analysis with high resolution and sensitve systemPrincipal Investigator
- Principal Investigator
  
  IRINO Yasuhiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Kobe University
Regulation of cell dynamism by phosphoinositides
- Principal Investigator
  
  Takenawa Tadaomi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
Molecular mechanisms of microglial chemotaxis induced by ATP
- Principal Investigator
  
  OHSAWA Keiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center of Neurology and Psychiatry
ATPを介したニューロン・ミクログリア相互作用の分子基盤
- Principal Investigator
  
  高坂新一
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Center of Neurology and Psychiatry

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Effects of Elaidic Acid on HDL Cholesterol Uptake Capacity2021
- Author(s)
  Takuya Iino, Ryuji Toh, Manabu Nagao, Masakazu Shinohara, Amane Harada, Katsuhiro Murakami, Yasuhiro Irino, Makoto Nishimori, Sachiko Yoshikawa, Yutaro Seto, Tatsuro Ishida, Ken-Ichi Hirata
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 9 Pages: 3112-3112
- DOI
  10.3390/nu13093112
- NAID
  120007159890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08490
[Journal Article] Fibronectin-containing High-Density Lipoprotein is Associated with Cancer Cell Adhesion and Proliferation2020
- Author(s)
  Eriko Hisamatsu, Manabu Nagao, Ryuji Toh, Yasuhiro Irino, Takuya Iino, Tetsuya Hara, Hidekazu Tanaka, Seimi Satomi-Kobayashi, Tatsuro Ishida, Ken-ichi Hirata
- Journal Title
  
  Kobe J. Med. Sci
  
  Volume: 66
- NAID
  120006975804
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08490
[Journal Article] Fibronectin-containing High-Density Lipoprotein is Associated with Cancer Cell Adhesion and Proliferation2020
- Author(s)
  Eriko Hisamatsu, Manabu Nagao, Ryuji Toh, Yasuhiro Irino, Takuya Iino, Tetsuya Hara, Hidekazu Tanaka, Seimi Satomi-Kobayashi, Tatsuro Ishida, Ken-Ichi Hirata
- Journal Title
  
  Kobe J Med Sci .
  
  Volume: 66
- NAID
  120006975804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08072
[Journal Article] Association of cholesterol uptake capacity, a novel indicator for HDL functionality, and coronary plaque properties: An optical coherence tomography-based observational study2020
- Author(s)
  Oshita T、Toh R、Nagano Y、Kuroda K、Nagasawa Y、Harada A、Murakami K、Kiriyama M、Yoshikawa K、Miwa K、Kubo T、Iino T、Nagao M、Irino Y、Hara T、Shinohara M、Otake H、Shinke T、Nakajima K、Ishida T、Hirata Ken-ichi
- Journal Title
  
  Clinica Chimica Acta
  
  Volume: 503 Pages: 136-144
- DOI
  10.1016/j.cca.2020.01.001
- NAID
  120006824021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-18K08073, KAKENHI-PROJECT-19K08490, KAKENHI-PROJECT-17K09553
[Journal Article] A Novel Indicator for HDL Functionality2019
- Author(s)
  Irino Yasuhiro、Toh Ryuji、Ishida Tatsuro
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 26 Issue: 11 Pages: 945-946
- DOI
  10.5551/jat.ED111
- NAID
  130007740418
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2019-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-19K08490
[Journal Article] Impaired Cholesterol‐Uptake Capacity of HDL Might Promote Target‐Lesion Revascularization by Inducing Neoatherosclerosis After Stent Implantation2019
- Author(s)
  Nagano Y, Otake H, Toba T, Kuroda K, Shinkura Y, Tahara N, Tsukiyama Y, Yanaka K, Yamamoto H, Nagasawa A, Onishi H, Sugizaki Y, Takeshige R, Harada A, Murakami K, Kiriyama M, Oshita T, Irino Y, Kawamori H, Ishida T, Toh R, Shinke T, Hirata KI.
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 8 Issue: 9
- DOI
  10.1161/jaha.119.011975
- NAID
  120006733129
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-17K09553, KAKENHI-PROJECT-18K08073
[Journal Article] Elevated Serum Elaidic Acid Predicts Risk of Repeat Revascularization After Percutaneous Coronary Intervention in Japan2019
- Author(s)
  Oshita Toshihiko、Toh Ryuji、Shinohara Masakazu、Mori Kenta、Irino Yasuhiro、Nagao Manabu、Hara Tetsuya、Otake Hiromasa、Ishida Tatsuro、Hirata Ken-ichi
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 5 Pages: 1032-1038
- DOI
  10.1253/circj.CJ-18-1175
- NAID
  130007636975
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-04-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-17K09579
[Journal Article] Serum concentration of full-length- and carboxy-terminal fragments of endothelial lipase predicts future cardiovascular risks in patients with coronary artery disease2019
- Author(s)
  Nagao Manabu、Miyashita Kazuya、Mori Kenta、Irino Yasuhiro、Toh Ryuji、Hara Tetsuya、Hirata Ken-ichi、Shinohara Masakazu、Nakajima Katsuyuki、Ishida Tatsuro
- Journal Title
  
  Journal of Clinical Lipidology
  
  Volume: 13 Issue: 5 Pages: 839-846
- DOI
  10.1016/j.jacl.2019.07.007
- NAID
  120007002630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-18K08073, KAKENHI-PROJECT-17K09579
[Journal Article] Identification of novel serum markers for the progression of coronary atherosclerosis in WHHLMI rabbits, an animal model of familial hypercholesterolemia2019
- Author(s)
  Shiomi Masashi、Takeda Hiroaki、Irino Yasuhiro、Kimura Norie、Yamada Satoshi、Kuniyoshi Nobue、Kikumori Akio、Koike Yu、Koike Tomonari、Yoshida Masaru、Izumi Yoshihiro、Shinohara Masakazu、Bamba Takeshi、Ishida Tatsuro
- Journal Title
  
  Atherosclerosis
  
  Volume: 284 Pages: 18-23
- DOI
  10.1016/j.atherosclerosis.2019.02.020
- NAID
  120006850489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08072, KAKENHI-PROJECT-23300157, KAKENHI-PROJECT-17K09579, KAKENHI-PROJECT-18H01800
[Journal Article] Glutamate production from ammonia via glutamate dehydrogenase 2 activity supports cancer cell proliferation under glutamine depletion2018
- Author(s)
  Takeuchi Yukiko、Nakayama Yasumune、Fukusaki Eiichiro、Irino Yasuhiro
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 495 Issue: 1 Pages: 761-767
- DOI
  10.1016/j.bbrc.2017.11.088
- NAID
  120006545118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07115
[Journal Article] Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma2016
- Author(s)
  Hiroaki Nagashima, Kazuhiro Tanaka, Takashi Sasayama, Yasuhiro Irino, Naoko Sato, Yukiko Takeuchi, Katsusuke Kyotani, Akitake Mukasa, Katsu Mizukawa, Junichi Sakata, Yusuke Yamamoto, Kohkichi Hosoda, Tomoo Itoh, Ryohei Sasaki, and Eiji Kohmura
- Journal Title
  
  Neuro-Oncology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26830073
[Journal Article] Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma2016
- Author(s)
  41.Nagashima H, Tanaka K, Sasayama T, Irino Y, Sato N, Takeuchi Y, Kyotani K, Mukasa A, Mizukawa K, Sakata J, Yamamoto Y, Hosoda K, Itoh T, Sasaki R, Kohmura E
- Journal Title
  
  Neuro Oncol.
  
  Volume: 18(11) Pages: 1559-1568
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462181
[Journal Article] Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment.2015
- Author(s)
  Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H, Satoh N, Kyotani K, Mizowaki T, Imahori T, Ejima Y, Masui K, Gini B, Yang H, Hosoda K, Sasaki R, Mischel PS, Kohmura E.
- Journal Title
  
  J Clin Invest
  
  Volume: 125 Issue: 4 Pages: 1591-602
- DOI
  10.1172/jci78239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462158, KAKENHI-PROJECT-26830073, KAKENHI-PROJECT-15K09996, KAKENHI-PROJECT-26462181, KAKENHI-PROJECT-25462258, KAKENHI-PROJECT-25670535, KAKENHI-PROJECT-25293265, KAKENHI-PROJECT-25293309
[Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion, cell migration and invasion in human breast cancer2014
- Author(s)
  Tokuda E., Itoh T., Hasegawa J., Ijuin T., Takeuchi Y., Irino, Y., Fukumoto M., and Takenawa T.
- Journal Title
  
  Cancer Res. 74, 3054-3066 (2014)
  
  Volume: 74 Pages: 3054-3066
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23227005
[Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion, and invasive cell migration in human breast cancer2014
- Author(s)
  Tokuda E., Itoh T., Hasegawa J., Ijuin T., Takeuchi Y., Irino, Y., Fukumoto M., and Takenawa T.
- Journal Title
  
  Cancer Res.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23227005
[Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion and invasive cell migration in human breast cancer.2014
- Author(s)
  Tokuda, E., Itoh, T., Hasegawa, J., Ijuin, T., Takeuchi, Y., Irino, Y., Fukumoto, M., Takenawa, T.
- Journal Title
  
  Cancer Res.
  
  Volume: 74 Issue: 11 Pages: 3054-3066
- DOI
  10.1158/0008-5472.can-13-2441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24113715, KAKENHI-PROJECT-24570216, KAKENHI-PROJECT-24650621, KAKENHI-PROJECT-24701005, KAKENHI-PROJECT-25460365
[Journal Article] Nucleoredoxin regulates glucose metabolism via phosphofructokinase 1.2013
- Author(s)
  Funato Y, Hayashi T, Irino Y, Takenawa T, Miki H.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 440 Pages: 737-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23227005
[Journal Article] Quantification and visualization of phosphoinositides by quantum dot-labeled specific binding-domain probes.2012
- Author(s)
  Irino Y
- Journal Title
  
  J. Lipid Res.
  
  Volume: 53 Issue: 4 Pages: 810-819
- DOI
  10.1194/jlr.d019547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23227005, KAKENHI-PROJECT-24570216, KAKENHI-PUBLICLY-24113715
[Journal Article] Quantification and visualization of phosphoinositides by quantum dot-labeled specific binding-domain probes2012
- Author(s)
  Irino Y, Tokuda E, Hasegawa J, Itoh T, Takenawa T
- Journal Title
  
  J.Lipid.Res.
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23227005
[Journal Article] Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography-mass spectrometry2012
- Author(s)
  Yoshida M, Hatano N, Nishiumi S, Irino Y, Izumi Y, Takenawa T, Azuma T
- Journal Title
  
  J. Gastroenterol
  
  Volume: 47(1) Issue: 1 Pages: 9-20
- DOI
  10.1007/s00535-011-0493-8
- NAID
  10030295488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501296, KAKENHI-PROJECT-24700455, KAKENHI-PROJECT-24701005
[Journal Article] Inhibitory effects of glycyrrhetinic acid on DNA polymerase and inflammatory activities.2011
- Author(s)
  Ishida T, Mizushina Y, Yagi S, IrinoY, Nishiumi S, Miki I, Kondo Y, Mizuno S, Yoshida H, Azuma T, Yoshida M.
- Journal Title
  
  Evid Based Complement Alternat Med.Epub
  
  Volume: 2012 Pages: 1-9
- DOI
  10.1155/2012/650514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590156, KAKENHI-PROJECT-24580205
[Journal Article] Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia2008
- Author(s)
  Yasuhiro Irino
- Journal Title
  
  Journal of Neuroscience Research(http://www3.interscience.wiley.com/cgi-bin/fulltext/117882441/HTMLSTART) (in press)(Webで公開中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500307
[Journal Article] Akt activation is involved in P2Y12 receptor-mediated chemotaxis o microglia2008
- Author(s)
  Irino, Y., Nakamura, Y., moue, K., Kohsaka, S.andOhsawa, K
- Journal Title
  
  J.Neurosci.Res. In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15082213
[Journal Article] Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia.2008
- Author(s)
  Irino Y, Nakamura Y, Inoue K, Kohsaka S, Ohsawa K.
- Journal Title
  
  J. Neurosci. Res. 86
  
  Pages: 1511-1519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500307
[Journal Article] nvolvement of P2X4 and P2Y12 receptors in ATP-induced microglia chemotaxis.2007
- Author(s)
  Ohsawa, K., Irino, Y., Nakamura, Y., Akazawa, C., Inoue, K, Kohsaka, S.
- Journal Title
  
  Glia 55
  
  Pages: 604-616
- Data Source
  KAKENHI-PROJECT-15082213
[Journal Article] Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis.2007
- Author(s)
  Ohsawa K, Irino Y, Nakamura Y, Akazawa C Inoue K and Kohsaka S.
- Journal Title
  
  GLIA 55
  
  Pages: 604-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500307
[Presentation] Searching for modulating factor of cholesterol uptake capacity, a novel indicator for HDL functionality2018
- Author(s)
  Toshihiko Oshita, Ryuji Toh,Mitsumasa Okano, Shigeyasu Tsuda, Koichi Watanabe, Seimi Kobayashi, Tetsuya Hara, Masakazu Shinohara, Yasuhiro Irino, Katsuhiro Murakami, Amane Harada, Tatsuro Ishida, Ken-ichi Hirata
- Organizer
  第50回　日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K08072
[Presentation] グルタミン酸デヒドロゲナーゼ2はアンモニアからグルタミン酸を産出し、グルタミン飢餓状態の細胞増殖を助ける2018
- Author(s)
  入野　康宏
- Organizer
  第43回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-16K07115
[Presentation] HDL機能の新規評価法“Cholesteroluptakecapacity”とOCT解析による冠動脈プラーク病変性状の比較検討2018
- Author(s)
  尾下寿彦、杜隆嗣、入野康宏、黒田浩史、永野雄一郎、長澤圭典、大竹寛雅、新家俊郎、石田達郎、平田健一
- Organizer
  第55回　日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08072
[Presentation] Cholesterol Uptake Capacity, a Novel Indicator for HDL Functionality, Versus Cholesterol Efflux Capacity in Association with Coronary Plaque Lipid Burden2018
- Author(s)
  Toshihiko Oshita, Ryuji Toh, Mitsumasa Okano, Koichi Watanabe, Yuichiro Nagano, Amane Harada, Katsuhiro Murakami, Seimi Kobayashi, Masakazu Shinohara, Tetsuya Hara, Yasuhiro Irino, Hiromasa Otake,Tatsuro Ishida, Ken-ichi Hirata.
- Organizer
  American Heart Association Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08072
[Presentation] グルタミン酸デヒドロゲナーゼ2はアンモニアからグルタミン酸を産出し、グルタミン飢餓状態の細胞増殖を助ける2018
- Author(s)
  入野　康宏
- Organizer
  がんと代謝研究会・若手の会
- Data Source
  KAKENHI-PROJECT-16K07115
[Presentation] アンモニアを利用するがん細胞は栄養飢餓状態でも生存できる2017
- Author(s)
  入野　康宏、竹内　由紀子、中山　泰宗、福崎　英一郎
- Organizer
  第42回日本医用マススペクトル学会
- Data Source
  KAKENHI-PROJECT-16K07115
[Presentation] Utilization of ammonia supports cell survival under glutamine depletion2017
- Author(s)
  竹内　由紀子、中山　泰宗、福崎　英一郎、入野　康宏
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K07115
[Presentation] アンモニアを利用するがん細胞は栄養飢餓状態でも生存できる2017
- Author(s)
  入野　康宏、竹内　由紀子、中山　泰宗、福崎　英一郎
- Organizer
  第5回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-16K07115
[Presentation] IDH遺伝子変異グリオーマのグルタミン代謝機構2016
- Author(s)
  田中一寛、篠山隆司、長嶋宏明、佐藤直子、入野康宏、甲村英二
- Organizer
  第34回日本脳腫瘍学会
- Place of Presentation
  山梨
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] Detection of IDH1 mutations in vivo by magnetic resonance spectroscopy of glutamate and 2-hydroxyglutarate in human brain gliomas2016
- Author(s)
  Tanaka K, Nagashima H, Sasayama T, Satoh N, Irino Y, Kyotani K, Kohmura E
- Organizer
  The 21st International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Bankoku Shinryokan, Okinawa
- Year and Date
  2016-04-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] 悪性グリオーマのグルタミン代謝機構2016
- Author(s)
  田中一寛、篠山隆司、長嶋宏明、佐藤直子、入野康宏、甲村英二
- Organizer
  第75回日本脳神経外科学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] Detection of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for diagnosing IDH1 mutant glioma2016
- Author(s)
  Tanaka K, Nagashima H, Sasayama T, Satoh N, Irino Y, Kohmura E
- Organizer
  EANO 2016 meeting
- Place of Presentation
  Mannheim, GERMANY
- Year and Date
  2016-10-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] 悪性グリオーマのmTORシグナル阻害薬に対する代償的グルタミン代謝機構2015
- Author(s)
  田中一寛、篠山隆司、入野康宏、佐藤直子、長嶋宏明、甲村英二
- Organizer
  第33回日本脳腫瘍学会学術集会
- Place of Presentation
  京都
- Year and Date
  2015-12-06
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] 悪性グリオーマのグルタミン代謝による代償的mTOR阻害薬耐性機構2015
- Author(s)
  田中一寛、篠山隆司、入野康宏、佐藤直子、長嶋宏明、甲村英二
- Organizer
  第74回日本脳神経外科学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] 悪性グリオーマのグルタミン代謝による代償的mTOR阻害薬耐性機構2015
- Author(s)
  田中一寛、篠山隆司、入野康宏、佐藤直子、長嶋宏明、甲村英二
- Organizer
  第3回がんと代謝研究会
- Place of Presentation
  金沢
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] Increasing expression of glutaminase C (GAC) mRNA in malignant gliomas2015
- Author(s)
  Kazuhiro Tanaka, Takashi Sasayama, Yasuhiro Irino, Hiroaki Nagashima, Naoko Satoh, Paul S. Mischel, and Eiji Kohmura
- Organizer
  20th Annual Scientific Meeting and Education Day of the society for Neuro-Oncology
- Place of Presentation
  San Antonio, Texas、USA
- Year and Date
  2015-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] PI3阻害剤が代謝に与える影響のプロファイリング2013
- Author(s)
  入野　康宏, 平田　悠、竹内　由紀子、波多野　直哉、山田　小弓、竹縄　忠臣
- Organizer
  第65回日本細胞生物学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24701005
[Presentation] 入野康宏,平田悠、竹内由紀子、波多野直哉、山田小弓、竹縄忠臣PI3阻害剤が代謝に与える影響のプロファイリング2013
- Author(s)
  入野康宏,平田悠、竹内由紀子、波多野直哉、山田小弓、竹縄忠臣
- Organizer
  第65回日本細胞生物学会
- Place of Presentation
  名古屋 (フラッシュトーク発表、ポスター発表)
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-24701005
[Presentation] The Profiling of the Effects of Adenomatous Polyposis Coli (APC) Mutation on the Cellular Proteome in Colorectal Cancer Cells.2013
- Author(s)
  Irino Y, Koshiyama A, Ichibangase T, Imai K, Yoshida M.
- Organizer
  HUPO 12th Annual World Congress
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-24701005
[Presentation] The Profiling of the Effects of Adenomatous Polyposis Coli (APC) Mutation on the Cellular Proteome in Colorectal Cancer Cells2012
- Author(s)
  Irino Y, Koshiyama A, Ichibangase T, Imai K, Yoshida M
- Organizer
  HUPO 12^<th> Annual World Congress
- Place of Presentation
  Pacifico Yokohama, Japan (Poster presentation)
- Year and Date
  2012-09-17
- Data Source
  KAKENHI-PROJECT-24701005
[Presentation] Characterization of breast cancer cells with metabolic profiling2012
- Author(s)
  入野康宏,平田悠、竹内由紀子、波多野直哉、竹縄忠臣
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡 (ポスター発表)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-24701005
[Presentation] ATP受容体P2Y12を介したインテグリンβ1活性化によるミクログリア突起伸長調節2008
- Author(s)
  大澤圭子、中村泰子、入野康宏、鈴木恵里、佐柳友規、井上和秀、高坂新一
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山国際会議場
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-18500307
[Presentation] ATP受容体P2Y1 2を介したインテグリンβ 1 活性化によるミクログリア突起伸長調節2008
- Author(s)
  大澤圭子、中村泰子、入野康宏、鈴木恵里、佐柳友規、井上和秀、高坂新一
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-18500307
[Presentation] Akt activation is crucial for P2Y12 receptor-mediated chemotaxis of microglia .2006
- Author(s)
  入野康宏、大澤圭子、中村泰子、井上和秀、高坂新一
- Organizer
  第28回日本生物学的精神医学会・第36回日本神経精神薬理学会・第49回日本神経化学会大会合同年会
- Place of Presentation
  名古屋
- Year and Date
  2006-09-14
- Data Source
  KAKENHI-PROJECT-18500307
[Presentation] Intracellular signaling underlying ATP-induced chemotaxis of microglia.2006
- Author(s)
  Ohsawa K, Irino Y, Nakamura Y, Akazawa C Inoue K, Kohsaka S.
- Organizer
  The 17^<th> International symposium on Adenosine and Adenine Nucleotides
- Place of Presentation
  Italy
- Year and Date
  2006-05-25
- Data Source
  KAKENHI-PROJECT-18500307
[Presentation] Akt activation is crucial for P2Y12 receptor-mediated chem otaxis of microglia .2006
- Author(s)
  Irino Y, Ohsawa K, Nakamura Y, Inoue K, Kohsaka S.
- Organizer
  The 20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11^<th> FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-21
- Data Source
  KAKENHI-PROJECT-18500307
[Presentation] mTORシグナル阻害による悪性グリオーマ細胞内グルタミン代謝機構の変化
- Author(s)
  田中一寛、篠山隆司、入野康宏、高田孔美、長嶋宏明、甲村英二
- Organizer
  第2回がんと代謝研究会
- Place of Presentation
  東京
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] Glutaminase-mediated metabolic pathway involves glioblastoma resistance to mTOR-targeted therapies
- Author(s)
  Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H, Masui k, Gini B, Yang H, Mischel PS, and Kohmura E
- Organizer
  19th World Congress on Advances in Oncology& 17th International Symposium on Molecular Medicine
- Place of Presentation
  Athens, Greece
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] Glutaminase-mediated metabolic pathway involves glioblastoma resistance to mTOR-targeted therapies
- Author(s)
  Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H, Masui k, Gini B, Yang H, Mischel PS, and Kohmura E
- Organizer
  The 11th Meeting of Asian Society for Neuro-Oncology
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-09-11 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26462181
[Presentation] Glutaminase-mediated metabolic pathway involves glioblastoma resistance to mTOR-targeted therapies
- Author(s)
  Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H, Masui k, Gini B, Yang H, Mischel PS, and Kohmura E
- Organizer
  19th Annual Scientific Meeting and Education Day of the society for Neuro-Oncology
- Place of Presentation
  Miami, Florida (USA)
- Year and Date
  2014-11-13 – 2014-11-16
- Invited
- Data Source
  KAKENHI-PROJECT-26462181

1. OHSAWA Keiko (40392435)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. MIZUSHINA Yoshiyuki (20307705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TANAKA KAZUHIRO (70467661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
4. Takenawa Tadaomi (40101315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. ITOH Toshiki (30313092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. IJUIN Takeshi (00361626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. TSUJITA Kazuya (10457054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TOKUDA Emi (70621960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. HASEGAWA Junya (00533788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. Ishida Taturo (00379413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. 高坂新一 (50112686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 内野茂夫 (30392434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 権田裕子 (60424181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 和賀央子 (80462795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 橋本学 (20415566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 奥野孝枝 (10402083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 篠山隆司 (10379399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
18. 杜隆嗣 (50379418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 神鳥和代

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HOSODA Kohkichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. MIZUNO Naruhito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 波多野直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IRINO Yasuhiro 入野 康宏

入野 康宏 イリノ ヤスヒロ

Research Projects

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Co-Researchers

Elucidation of the interaction between cells and HDL with multifaceted actionsPrincipal Investigator

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Elucidating molecular mechanisms of HDL functionality

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Understanding of glutamine metabolism in cancer cellsPrincipal Investigator

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Integrated analyses of GBM cell lines, in vivo xenograft models, and clinical samples to examine the glutamine metabolism in response to mTOR-targeted treatments

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Understanding metabolic regulation of epithelial-mesenchymal transitionPrincipal Investigator

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Screening of DNA polymerase species selective inhibitors from nutrients and food components, and analysis of novel healthy functions

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Comprehensive metabolome analysis with high resolution and sensitve systemPrincipal Investigator

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Regulation of cell dynamism by phosphoinositides

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Molecular mechanisms of microglial chemotaxis induced by ATP

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ATPを介したニューロン・ミクログリア相互作用の分子基盤

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[Journal Article] Effects of Elaidic Acid on HDL Cholesterol Uptake Capacity2021

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[Journal Article] Fibronectin-containing High-Density Lipoprotein is Associated with Cancer Cell Adhesion and Proliferation2020

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[Journal Article] Fibronectin-containing High-Density Lipoprotein is Associated with Cancer Cell Adhesion and Proliferation2020

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IRINO Yasuhiro 入野康宏

入野康宏イリノヤスヒロ