YOSHIKAWA YASUNAGA 吉川泰永

… Alternative Names

Yoshikawa Yasunaga 吉川泰永

吉川泰永ヨシカワヤスナガ

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Researcher Number	00552043
Other IDs	https://orcid.org/0000-0003-4257-3088
Affiliation (Current)	2025: 北里大学, 獣医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 北里大学, 獣医学部, 准教授 2020: 北里大学, 獣医学部, 講師 2016 – 2018: 北里大学, 獣医学部, 講師 2012: 北里大学, 獣医学部, 講師 2011: 北里大学, 獣医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Integrative animal science / Clinical veterinary science Except Principal Investigator Basic Section 42020:Veterinary medical science-related / Basic veterinary science/Basic zootechnical science
Keywords	Principal Investigator BRCA2 / サイレンサー / 乳腺腫瘍 / 相同組換え修復 / 細胞分裂 / 細胞周期 / PLK1 / M期 / リン酸化 / 腫瘍 … More / 発現制御 / 発現調節 / 発現抑制 / DNA損傷修復 / プロモーター活性 / 転写 / ANXA2 / 癌 / 遺伝子 / 獣医学 / 癌抑制遺伝子 / 転写因子 / 転写抑制 / トランス因子 / シス因子 / 転写抑制因子 / 変異 / リスク診断 / イヌ … More Except Principal Investigator タンパク質 / ハマダラカ / 形成・分化機構 / オーシスト / マラリア原虫 / ファンコニ貧血 / 腫瘍化 / FANCC / 繊維芽細胞 / Fanconi anemia / DNA損傷修復 / Fanconi/BRCA経路 / FANCB / FANCL / 発癌防御機構 / ゾウ / アネキシンA5 / 下垂体 / GnRH / アネキシンＡ５ / 乳腺 / 前立腺 / 卵巣 / 組織リモデリング / マスト細胞 Less

マラリア原虫オーシスト形成・分化に関する分子機構の解明：壁構成蛋白質の探索から
- Principal Investigator
  
  筏井宏実
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Kitasato University
Is phosphorylation of BRCA2 in M phase associated with tumorigenesis in dogs?Principal Investigator
- Principal Investigator
  
  吉川泰永
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Kitasato University
Elucidation of cancer resistance mechanisms in elephants
- Principal Investigator
  
  Orino Koichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Kitasato University
Tumorigenesis by transcriptional suppression of Breast cancer 2, early onset (BRCA2) by ANXA2Principal Investigator
- Principal Investigator
  
  Yoshikawa Yasunaga
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Kitasato University
Analysis of novel transcriptional suppressing mechanism in canine BRCA2Principal Investigator
- Principal Investigator
  
  Yoshikawa Yasunaga
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Integrative animal science
- Research Institution
  Kitasato University
A novel physiological function of mast cells on tissue remodeling
- Principal Investigator
  
  KAWAMINAMI Mitsumori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Kitasato University
イヌ乳腺腫瘍原因遺伝子ＢＲＣＡ２を利用した乳腺腫瘍発症リスク診断法の確立Principal Investigator
- Principal Investigator
  
  吉川泰永
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Kitasato University

All 2023 2022 2021 2020 2018 2017 2016 2012 2011

All Journal Article Presentation

[Journal Article] Formation of free oocysts in <i>Anopheles</i> mosquitoes injected with <i>Plasmodium</i> ookinetes2023
- Author(s)
  HARAGUCHI Asako、TAKANO Makoto、HAKOZAKI Jun、NAKAYAMA Kazuhiko、NAKAMURA Sakure、YOSHIKAWA Yasunaga、FUKUMOTO Shinya、KUSAKISAKO Kodai、IKADAI Hiromi
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 85 Issue: 9 Pages: 921-928
- DOI
  10.1292/jvms.23-0099
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19235, KAKENHI-PROJECT-23KJ1873, KAKENHI-PROJECT-19KK0175, KAKENHI-PROJECT-23K05575, KAKENHI-PROJECT-21K05960, KAKENHI-PROJECT-23K23775
[Journal Article] Comparisons of beta2-microglobulin, apolipoprotein A1, and immunoglobulins (IgG and IgM) detected in the serum and urine from individual cats2023
- Author(s)
  Katagai Michio、Imatomi Haruka、Tshuchida Yashuhiko、Katayama Kinya、Yoshikawa Yasunaga、Orino Koichi
- Journal Title
  
  Austral Journal of Veterinary Sciences
  
  Volume: 55 Issue: 3 Pages: 197-202
- DOI
  10.4206/ajvs.553.06
- Data Source
  KAKENHI-PROJECT-21K05960
[Journal Article] Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway2023
- Author(s)
  Kupculak Marian、Bai Fengxiang、Luo Qiang、Yoshikawa Yasunaga、Lopez-Martinez David、Xu Hannan、Uphoff Stephan、Cohn Martin A.
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 7 Pages: 112721-112721
- DOI
  10.1016/j.celrep.2023.112721
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05575, KAKENHI-PROJECT-21K05960
[Journal Article] A Highly Conserved Region in BRCA2 Suppresses the RAD51-Interaction Activity of BRC Repeats2023
- Author(s)
  Zhu Zida、Kitano Taisuke、Morimatsu Masami、Ochiai Kazuhiko、Ishiguro-Oonuma Toshina、Oosumi Kosuke、Lin Xianghui、Orino Koichi、Yoshikawa Yasunaga
- Journal Title
  
  Veterinary Sciences
  
  Volume: 10 Issue: 2 Pages: 145-145
- DOI
  10.3390/vetsci10020145
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05998, KAKENHI-PROJECT-20K06417, KAKENHI-PROJECT-18H02334
[Journal Article] BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents2022
- Author(s)
  Zhu Zida、Kitano Taisuke、Morimatsu Masami、Tanaka Arisa、Morioka Ryo、Lin Xianghui、Orino Koichi、Yoshikawa Yasunaga
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 7 Pages: 4060-4060
- DOI
  10.3390/ijms23074060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05998, KAKENHI-PROJECT-20K06417, KAKENHI-PROJECT-18H02334
[Journal Article] Reduced translation efficiency due to novel splicing variants in 5′ untranslated region and identification of novel cis-regulatory elements in canine and human BRCA22021
- Author(s)
  Yoshikawa Yasunaga、Kozuma Hajime、Morimatsu Masami、Sugawara Kaori、Orino Koichi
- Journal Title
  
  BMC Molecular and Cell Biology
  
  Volume: 22 Issue: 1 Pages: 2-2
- DOI
  10.1186/s12860-020-00336-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02334, KAKENHI-PROJECT-20K06417
[Journal Article] Identification of the core motif of the BRCA2 C-terminal RAD51-binding domain by comparing canine and human BRCA22021
- Author(s)
  YOSHIKAWA Yasunaga、MORIMATSU Masami、OCHIAI Kazuhiko、ISHIGURO-OONUMA Toshina、MORIOKA Ryo、OKUDA Kento、ORINO Koichi
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 83 Issue: 5 Pages: 759-766
- DOI
  10.1292/jvms.21-0006
- NAID
  130008036476
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02334, KAKENHI-PROJECT-20K06417
[Journal Article] Effects of the missense mutations in canine BRCA2 on BRC repeat 3 functions and comparative analyses between canine and human BRC repeat 32012
- Author(s)
  Yoshikawa Y, Ochiai K, Morimatsu M, Suzuki Y, Wada S, Taoda T, Iwai S, Chikazawa S, Orino K, Watanabe K
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 10 Pages: e45833-e45833
- DOI
  10.1371/journal.pone.0045833
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580399, KAKENHI-PROJECT-23780326, KAKENHI-PROJECT-24780313
[Journal Article] Establishment of a PCR analysis method for canine BRCA22012
- Author(s)
  Yoshikawa Y, Morimatsu M, Ochiai K, Okuda K, Taoda T, Chikazawa S, Shimamura A, Omi T, Bonkobara M, Orino K, Watanabe K.
- Journal Title
  
  BMC Res Notes
  
  Volume: (in press) Issue: 1 Pages: 173-173
- DOI
  10.1186/1756-0500-5-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580395, KAKENHI-PROJECT-23580399, KAKENHI-PROJECT-23780326, KAKENHI-PROJECT-24380173, KAKENHI-PROJECT-24780313
[Presentation] ハマダラカのマラリア原虫感染に対する新たな応答分子の探索2023
- Author(s)
  原口麻子, 高野真, 箱崎純, 中山和彦, 中村咲蓮, 吉川泰永, 福本晋也, 草木迫浩大, 筏井宏実
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K05960
[Presentation] Reduced translation efficiency due to novel splicing variants in 5′ untranslated region and identification of novel cis-regulatory elements in canine and human BRCA22023
- Author(s)
  Yasunaga Yoshikawa, Hajime Kozuma, Chihiro Mochizuki, Zida Zhu, Masami Morimatsu, Koichi Orino
- Organizer
  Eukaryotic DNA Replication & Genome Maintenance
- Data Source
  KAKENHI-PROJECT-23K05575
[Presentation] Reduced translation efficiency due to novel splicing variants in 5′ untranslated region and identification of novel cis-regulatory elements in canine and human BRCA22023
- Author(s)
  Yasunaga Yoshikawa, Hajime Kozuma, Chihiro Mochizuki, Zida Zhu, Masami Morimatsu, Koichi Orino
- Organizer
  Eukaryotic DNA Replication & Genome Maintenance
- Data Source
  KAKENHI-PROJECT-21K05960
[Presentation] Highly conserved region in BRCA2 suppresses the RAD51-interaction activity of BRC repeats2023
- Author(s)
  Zida Zhu, Taisuke Kitano, Masami Morimatsu, Kazuhiko Ochiai, Toshina Ishiguro-Oonuma, Xianghui Lin, Koichi Orino, Yasunaga Yoshikawa
- Organizer
  Eukaryotic DNA Replication & Genome Maintenance
- Data Source
  KAKENHI-PROJECT-23K05575
[Presentation] ゾウFANCL-FANCB間の相互作用はヒトホモログより強い2023
- Author(s)
  日置七海, 北野泰佑, 朱子達, 武田一貴, 折野宏一, 吉川泰永
- Organizer
  第166回日本獣医学会学術集会講演要旨集
- Data Source
  KAKENHI-PROJECT-21K05960
[Presentation] がん抑制遺伝子BRCA2の5’非翻訳領域と新規シスエレメントによる発現調節2023
- Author(s)
  吉川泰永, 上妻創, 望月千尋, ZHU Zida, 北野泰佑, 森松正美, 折野宏一
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K05575
[Presentation] ゾウFANCL-FANCB間の相互作用はヒトホモログより強い2023
- Author(s)
  日置七海, 北野泰佑, 朱子達, 武田一貴, 折野宏一, 吉川泰永
- Organizer
  第166回日本獣医学会学術集会講演要
- Data Source
  KAKENHI-PROJECT-23K05575
[Presentation] がん抑制遺伝子BRCA2の5’非翻訳領域と新規シスエレメントによる発現調節2023
- Author(s)
  吉川泰永, 上妻創, 望月千尋, ZHU Zida, 北野泰佑, 森松正美, 折野宏一
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K05960
[Presentation] ハマダラカのマラリア原虫感染に対する新たな応答分子の探索2023
- Author(s)
  原口麻子, 高野真, 箱崎純, 中山和彦, 中村咲蓮, 吉川泰永, 福本晋也, 草木迫浩大, 筏井宏実
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K05575
[Presentation] がん抑制遺伝子BRCA2の新規転写調節機構の解明2023
- Author(s)
  望月千尋, 上妻創, 朱子達, 北野泰佑, 折野宏一, 森松正美, 吉川泰永
- Organizer
  第166回日本獣医学会学術集会講演要旨集
- Data Source
  KAKENHI-PROJECT-21K05960
[Presentation] Highly conserved region in BRCA2 suppresses the RAD51-interaction activity of BRC repeats2023
- Author(s)
  Zida Zhu, Taisuke Kitano, Masami Morimatsu, Kazuhiko Ochiai, Toshina Ishiguro-Oonuma, Xianghui Lin, Koichi Orino, Yasunaga Yoshikawa
- Organizer
  Eukaryotic DNA Replication & Genome Maintenance
- Data Source
  KAKENHI-PROJECT-21K05960
[Presentation] Plasmodium berghei(ネズミマラリア原虫)における減数分裂関連タンパク質Brca2の機能解析2022
- Author(s)
  木村駿太, 吉川泰永, 曽賀晃, 杉山真言, 朱子達, 中山和彦, 草木迫浩大, 北野泰祐, 折野宏一, 福本晋也, 筏井宏実
- Organizer
  第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06417
[Presentation] ネズミマラリア原虫Plasmodium bergheiにおける相同組換えタンパク質Brca2機能解析2022
- Author(s)
  吉川泰永、木村俊太、曽賀晃、杉山真言、朱子達、中山和彦、草木迫浩大、北野泰佑、折野宏一、福本晋也、筏井宏実
- Organizer
  第91回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-20K06417
[Presentation] BRCA2 C-terminal RAD51-binding domain confers resistance to DNA-damaging agents2022
- Author(s)
  朱子達、北野泰佑、森松正美、折野宏一、吉川泰永
- Organizer
  第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06417
[Presentation] ANXA2がイヌ血管肉腫細胞の遊走能に及ぼす影響2022
- Author(s)
  林香慧, 北野泰佑, 落合和彦, 酒井洋樹, 折野宏一, 吉川泰永
- Organizer
  第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06417
[Presentation] 癌抑制遺伝子Brca2のイントロン 1 における発現調節機構の解析2021
- Author(s)
  上妻創、吉川泰永、森松正美、落合和彦、折野宏一
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06417
[Presentation] 癌抑制遺伝子BRCA2の翻訳効率に影響を与えるスプライシングバリアント2020
- Author(s)
  吉川泰永、森松正美、上妻創、折野宏一
- Organizer
  第163回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06417
[Presentation] BRCA2の新規サイレンサー配列の同定と解析2018
- Author(s)
  吉川泰永、折野宏一
- Organizer
  第41回分子生物学会
- Data Source
  KAKENHI-PROJECT-16K18817
[Presentation] 新規FANCD2結合タンパク質D2AP2の機能解析2017
- Author(s)
  吉川泰永、五井勇人、大隅恒佑、折野宏一
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K18817
[Presentation] アネキシンA2は癌抑制遺伝子BRCA2の発現を調節する？？2016
- Author(s)
  吉川泰永、折野宏一
- Organizer
  第二回アネキシン研究会
- Place of Presentation
  札幌医科大学　北海道札幌市
- Data Source
  KAKENHI-PROJECT-16K18817
[Presentation] イヌ乳腺腫瘍で発見した癌関連遺伝子産物BRCA2における変異BRC repeat 3の機能解析2012
- Author(s)
  吉川　泰永
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学
- Data Source
  KAKENHI-PROJECT-23780326
[Presentation] 癌抑制遺伝子BRCA2のPCR法による変異解析法の確立2011
- Author(s)
  吉川泰永、森松正美、鈴木　優、西村百合香、落合和彦、折野宏一、垰田高広、近澤征史郎、岩井聡美、島村麻子、新井敏郎、渡辺清
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  大阪府立大学（大阪）
- Data Source
  KAKENHI-PROJECT-23780326
[Presentation] イヌおよびヒトBRCA2のBRC repeat 3領域におけるミスセンス変異の比較2011
- Author(s)
  吉川泰永、森松正美、落合和彦、折野宏一、和田成一、垰田高広、近澤征史郎、岩井聡美、渡辺清隆
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23780326

1. KAWAMINAMI Mitsumori (00153007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. YONEZAWA Tomohiro (10433715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HASHIMOTO Osamu (90317058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HASEGAWA Yoshihisa (40092001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Orino Koichi (60214235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. 佐々木宣哉 (20302614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 筏井宏実 (80327460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 草木迫浩大 (10838220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 福本晋也 (50376422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAZUHIKO Ochiai

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 森松正美

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. 盆子原誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIKAWA YASUNAGA 吉川 泰永

Yoshikawa Yasunaga 吉川 泰永

吉川 泰永 ヨシカワ ヤスナガ

Research Projects

Research Products

Co-Researchers

マラリア原虫オーシスト形成・分化に関する分子機構の解明：壁構成蛋白質の探索から

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Is phosphorylation of BRCA2 in M phase associated with tumorigenesis in dogs?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of cancer resistance mechanisms in elephants

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Tumorigenesis by transcriptional suppression of Breast cancer 2, early onset (BRCA2) by ANXA2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of novel transcriptional suppressing mechanism in canine BRCA2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel physiological function of mast cells on tissue remodeling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

イヌ乳腺腫瘍原因遺伝子ＢＲＣＡ２を利用した乳腺腫瘍発症リスク診断法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Formation of free oocysts in <i>Anopheles</i> mosquitoes injected with <i>Plasmodium</i> ookinetes2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Comparisons of beta2-microglobulin, apolipoprotein A1, and immunoglobulins (IgG and IgM) detected in the serum and urine from individual cats2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Highly Conserved Region in BRCA2 Suppresses the RAD51-Interaction Activity of BRC Repeats2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reduced translation efficiency due to novel splicing variants in 5′ untranslated region and identification of novel cis-regulatory elements in canine and human BRCA22021

Author(s)

Journal Title

DOI

Data Source

YOSHIKAWA YASUNAGA 吉川泰永

Yoshikawa Yasunaga 吉川泰永

吉川泰永ヨシカワヤスナガ