Hidenobu Mizuno 水野秀信

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MIZUNO Hidenobu 水野秀信

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Researcher Number	00567159
Other IDs	https://orcid.org/0000-0001-6262-7106
Affiliation (Current)	2026: 熊本大学, 国際先端医学研究機構, 特任准教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 熊本大学, 国際先端医学研究機構, 特任准教授 2013 – 2017: 国立遺伝学研究所, 個体遺伝研究系, 助教 2010 – 2011: 国立遺伝学研究所, 個体遺伝研究系, 助教
Review Section/Research Field	Principal Investigator Neurophysiology / General neuroscience / Basic Section 90110:Biomedical engineering-related / Transformative Research Areas, Section (IV) / Basic Section 46010:Neuroscience-general-related / Neuroscience in general Except Principal Investigator Basic Section 56060:Ophthalmology-related / Basic Section 46010:Neuroscience-general-related / Basic Section 51030:Pathophysiologic neuroscience-related / Transformative Research Areas, Section (IV) / Basic Section 44020:Developmental biology-related / Biological Sciences
Keywords	Principal Investigator 2光子イメージング / 大脳皮質 / カルシウムイメージング / 光遺伝学 / 樹状突起ダイナミクス / 単一細胞標識 / 生体イメージング / 神経回路形成 / 体性感覚野 / 2光子顕微鏡 … More / 神経科学 / 同期的神経活動 / 同期活動 / 活動依存的回路形成 / 生理学 / 臨界期 / 二光子顕微鏡 / バレル皮質 / バレル / NMDA型グルタミン酸受容体 / マウス遺伝学 / 感覚入力 / 非侵襲的治療 / 末梢感覚入力 / 生体光遺伝学 / 生体脳イメージング / 2光子生体イメージング / 自発的神経活動 / RasGAP / エレクトロポレーション / トランスジェニックマウス / GCaMP / 神経活動 / 新生仔生体観察 / 視床皮質回路 / モザイクノックアウト解析 / 新生仔イメージング / 新生児 / 覚醒下イメージング / 単一細胞遺伝子操作 / タイムラプスイメージング / 電気選考法 / マウス / 樹状突起 / ノックアウト / NMDA受容体 / in vivoイメージング / 遺伝学 / Cre/loxPシステム / 蛍光蛋白質 / 電気穿孔法 … More Except Principal Investigator 生体イメージング / Nav1.2 / ミトコンドリア / 緑内障 / 神経回路形成 / 同期活動 / 大脳皮質 / gap junction / 発達 / 神経回路 / 神経細胞形態 / 発達性およびてんかん性脳症 / 循環障害 / 炎症 / 網羅的解析 / 網膜循環障害 / 脳 / 脳自発活動 / グリア / 同期性 / 脳発達 / 自発活動 / 小脳 / グリア細胞 / シナプス / 脳疾患 / 半球間投射発達 / 神経活動 / 大脳皮質第５層 / イオンチャネル / 半球間投射 / 遺伝子改変マウス / 皮膚再生 / ニッチ / 力学的環境 / 領域化 / 細胞外マトリクス / 皮膚老化 / 三次元培養 / 細胞外環境 / 幹細胞不均一性 / 表皮幹細胞 / 生細胞イメージング / 前房注入による眼圧上昇モデル / 網膜循環 / 2光子励起顕微鏡 / 前房注入による高眼圧モデル / 視神経挫滅モデル / 多色同時励起による網膜生体イメージング / 経角膜的な網膜生体イメージング / 細胞種特異性 / 発達期 / gap junctionネットワーク / 回路形成 / ノックアウト / 体性感覚系 / 遺伝子 / 発生・分化 / 脳・神経 / 遺伝学 / 神経科学 / イメージング / 遺伝子ノックアウト / 発達期可塑性 / マウス Less

Understanding epilepsy caused by SCN2A mutations in terms of neuronal morphology change
- Principal Investigator
  
  玉川直 (中川直)
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kagoshima University
生体光遺伝学を用いた同期的神経活動の誘発による脳回路発達の改善Principal Investigator
- Principal Investigator
  
  水野秀信
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kumamoto University
生体イメージングと網羅的解析によるミトコンドリア面からみた緑内障とその治療法探索
- Principal Investigator
  
  瀧原祐史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kumamoto University
Interhemispheric projection control by modulating neural activity levels during development
- Principal Investigator
  
  Nakagawa-Tamagawa Nao
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kagoshima University
Design-build of brain by generation and transtion of multi-dimension spontaneous activity
- Principal Investigator
  
  Uesaka Naofumi
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  Institute of Science Tokyo
  Tokyo Medical and Dental University
The relationship between spontaneous activity and circuit formation in the cerebral cortexPrincipal Investigator
- Principal Investigator
  
  Mizuno Hidenobu
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  Kumamoto University
In vivo imaging of neonatal brain to elucidate the role of spontaneous synchronous activity in cortical circuit formationPrincipal Investigator
- Principal Investigator
  
  MIZUNO Hidenobu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kumamoto University
Novel intravital imaging of the retina to study retinal ganglion cell dysfunction related to mitochondria for glaucoma research
- Principal Investigator
  
  Takihara Yuji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kumamoto University
Compartmentalization of epithelial stem cells in skin development and homeostasis
- Principal Investigator
  
  Sada Aiko
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kyushu University
  Kumamoto University
Role of the gap junction network in the formation of cell type-specific neural circuits during developmental
- Principal Investigator
  
  Tamagawa Nao
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kagoshima University
In vivo imaging of neonatal brain to elcidate the mechanism of activity-dependent thalamocortical circuit formationPrincipal Investigator
- Principal Investigator
  
  Mizuno Hidenobu
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Kumamoto University
  National Institute of Genetics
In vivo imaging of neuronal activity in the developing cerebral cortexPrincipal Investigator
- Principal Investigator
  
  Mizuno Hidenobu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Institute of Genetics
In vivo 2-photon imaging of the cerebral cortex in neonatal micePrincipal Investigator
- Principal Investigator
  
  MIZUNO Hidenobu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Institute of Genetics
Analyses of mechanism for neuronal circuit refinement in barrel cortex by mouse genetics and electroporation methodPrincipal Investigator
- Principal Investigator
  
  MIZUNO Hidenobu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  National Institute of Genetics
Circuit remodeling during postnatal development in the mouse somatosensory cortex
- Principal Investigator
  
  Iwasato Takuji
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics

[Book] 神経回路の形成機構：哺乳類大脳皮質神経回路の生後発達再生医療シリーズ　脳神経系の再生医学、高橋惇・井村裕夫監、河崎洋志編2015
- Author(s)
  岩里琢治，水野秀信
- Total Pages
  169
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25640015
[Book] 脳神経系の発生・再生の融合的新展開（分担執筆）2014
- Author(s)
  岩里琢治、水野秀信
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PLANNED-22115009
[Journal Article] Cell-class-specific orofacial motor maps in mouse neocortex2025
- Author(s)
  Tamura Keita、Bech Pol、Mizuno Hidenobu、Veaute Lea、Crochet Sylvain、Petersen Carl C.H.
- Journal Title
  
  Current Biology
  
  Volume: 35 Issue: 6 Pages: 1382-1390.e5
- DOI
  10.1016/j.cub.2025.01.056
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05094, KAKENHI-PROJECT-24K03266
[Journal Article] In Vivo Visualization of Spontaneous Activity in Neonatal Mouse Sensory Cortex at a Single-neuron Resolution2023
- Author(s)
  Nakagawa-Tamagawa Nao、Egashira Takamitsu、Rao Madhura S.、Mizuno Hidenobu
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 201 Issue: 201
- DOI
  10.3791/65899
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06446, KAKENHI-ORGANIZER-22H05092, KAKENHI-PLANNED-22H05094
[Journal Article] In vivo two-photon calcium imaging of cortical neurons in neonatal mice2023
- Author(s)
  Egashira Takamitsu、Nakagawa-Tamagawa Nao、Abzhanova Elvira、Kawae Yuzuki、Kohara Ayami、Koitabashi Ryoko、Mizuno Hiromi、Mizuno Hidenobu
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 2 Pages: 102245-102245
- DOI
  10.1016/j.xpro.2023.102245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06446, KAKENHI-ORGANIZER-22H05092, KAKENHI-PLANNED-22H05094
[Journal Article] Short-Term Dendritic Dynamics of Neonatal Cortical Neurons Revealed by In Vivo Imaging with Improved Spatiotemporal Resolution2023
- Author(s)
  Wang Luwei、Nakazawa Shingo、Luo Wenshu、Sato Takuya、Mizuno Hidenobu、Iwasato Takuji
- Journal Title
  
  eNeuro
  
  Volume: 10 Issue: 11 Pages: 0142-23
- DOI
  10.1523/eneuro.0142-23.2023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18245, KAKENHI-PROJECT-20H03346, KAKENHI-ORGANIZER-22H05092, KAKENHI-PLANNED-22H05094
[Journal Article] Editorial: In vivo investigations on neurological disorders: From traditional approaches to forefront technologies2022
- Author(s)
  Curia Giulia、Estrada-Camarena Erika、Manjarrez Elias、Mizuno Hidenobu
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 1052089-1052089
- DOI
  10.3389/fnins.2022.1052089
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22H05092, KAKENHI-PLANNED-22H05094, KAKENHI-PROJECT-20K06876
[Journal Article] Ras GTPase-activating proteins control neuronal circuit development in barrel cortex layer 42022
- Author(s)
  Rao Madhura S.、Mizuno Hiromi、Iwasato Takuji、Mizuno Hidenobu
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 901774-901774
- DOI
  10.3389/fnins.2022.901774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18245, KAKENHI-ORGANIZER-22H05092, KAKENHI-PLANNED-22H05094, KAKENHI-PROJECT-20K06876, KAKENHI-PROJECT-20H03346
[Journal Article] Bone marrow imaging reveals the migration dynamics of neonatal hematopoietic stem cells2022
- Author(s)
  Takihara Yuji、Higaki Takumi、Yokomizo Tomomasa、Umemoto Terumasa、Ariyoshi Kazunori、Hashimoto Michihiro、Sezaki Maiko、Takizawa Hitoshi、Inoue Toshihiro、Suda Toshio、Mizuno Hidenobu
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 776-776
- DOI
  10.1038/s42003-022-03733-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-22K19549, KAKENHI-ORGANIZER-22H05092, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-20H03289, KAKENHI-PROJECT-20K09774, KAKENHI-PLANNED-18H05492
[Journal Article] Factors associated with the surgical outcomes of Baerveldt glaucoma implant for open-angle glaucoma, an age-related eye disease2022
- Author(s)
  Iraha Satoshi、Takihara Yuji、Urahashi Yui、Watanabe Takahiro、Nakamura Kenichi、Urahashi Mai、Watanabe-Kitamura Fumika、Nakashima Kei-Ichi、Takahashi Eri、Kojima Sachi、Tanihara Hidenobu、Inoue Toshihiro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1359-1359
- DOI
  10.1038/s41598-021-04570-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16899, KAKENHI-PROJECT-20K09774
[Journal Article] Elucidating mechanisms of neuronal circuit formation in layer 4 of the somatosensory cortex via intravital imaging2020
- Author(s)
  Rao Madhura S.、Mizuno Hidenobu
- Journal Title
  
  Neuroscience Research
  
  Volume: in press Pages: 47-53
- DOI
  10.1016/j.neures.2020.10.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06876
[Journal Article] NMDA Receptor Enhances Correlation of Spontaneous Activity in Neonatal Barrel Cortex2020
- Author(s)
  Mizuno Hidenobu、Rao Madhura S.、Mizuno Hiromi、Sato Takuya、Nakazawa Shingo、Iwasato Takuji
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 41 Issue: 6 Pages: 1207-1217
- DOI
  10.1523/jneurosci.0527-20.2020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06876, KAKENHI-PROJECT-20H03346, KAKENHI-PLANNED-16H06459
[Journal Article] TGF-β-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness2020
- Author(s)
  Tomoyo Matsumura, Tomokazu Fujimoto, Satoshi Iraha, Akiko Futakuchi, Yuji Takihara, Fumika Watanabe-Kitamura, Eri Takahashi, Miyuki Inoue-Mochita, Hidenobu Tanihara, Toshihiro Inoue
- Journal Title
  
  PLoS One
  
  Volume: 15 Issue: 11 Pages: 242626-242626
- DOI
  10.1371/journal.pone.0242626
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09774, KAKENHI-PROJECT-20K18371
[Journal Article] Patchwork-type spontaneous activity in neonatal barrel cortex layer 4 transmitted via thalamocortical projections.2018
- Author(s)
  Mizuno, H., Ikezoe, K., Nakazawa, S., Sato, T., Kitamura, K., Iwasato, T.
- Journal Title
  
  Cell Rep.
  
  Volume: 22 Issue: 1 Pages: 123-135
- DOI
  10.1016/j.celrep.2017.12.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06459, KAKENHI-PLANNED-17H06313, KAKENHI-PROJECT-17H03543, KAKENHI-PROJECT-16H06143, KAKENHI-PROJECT-15J03643, KAKENHI-PROJECT-16K14559, KAKENHI-PROJECT-15H04263
[Journal Article] In Vivo Two-photon Imaging of Cortical Neurons in Neonatal Mice2018
- Author(s)
  Mizuno H*, Nakazawa S, Iwasato T (* correspondence)
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 140 Issue: 140
- DOI
  10.3791/58340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06143, KAKENHI-PROJECT-16K14559, KAKENHI-PLANNED-16H06459, KAKENHI-PROJECT-15H04263
[Journal Article] Supernova: A Versatile Vector System for Single-Cell Labeling and Gene Function Studies in vivo.2016
- Author(s)
  Luo, W., Mizuno, H., Iwata, R., Nakazawa, S., Yasuda, K., Itohara, S., Iwasato, T.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 35747-35747
- DOI
  10.1038/srep35747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04263, KAKENHI-PROJECT-16H06143, KAKENHI-PROJECT-15J03643, KAKENHI-PROJECT-15K14322, KAKENHI-PROJECT-16K14559, KAKENHI-PLANNED-16H06459
[Journal Article] Developmental RacGAP α2-chimaerin signaling is a determinant of the morphological features of dendritic spines in adulthood.2015
- Author(s)
  Ryohei Iwata, Hiroshi Matsukawa, Kosuke Yasuda, Hidenobu Mizuno, Shigeyoshi Itohara, Takuji Iwasato
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 35 Pages: 13728-13744
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14322
[Journal Article] Developmental RacGAPa 2-chimaerin signaling is a determinant of the morphological features of dendritic spines in adulthood.2015
- Author(s)
  .Iwata, R., Matsukawa, H., Yasuda, K., Mizuno, H., Itohara, S., Iwasato, T.
- Journal Title
  
  J. Nerurosci.
  
  Volume: 35 Issue: 40 Pages: 13728-13744
- DOI
  10.1523/jneurosci.0419-15.2015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22115009, KAKENHI-PROJECT-15H04290, KAKENHI-PUBLICLY-15H01454, KAKENHI-PROJECT-15H04263
[Journal Article] Transcallosal projections require glycoprotein M6-dependent neurite growth and guidance.2014
- Author(s)
  S. Mita, P. Monasterio-Schrader, U. Fünfschilling, T. Kawasaki, H. Mizuno, T. Iwasato, K.-A. Nave, H. B. Werner, and T. Hirata
- Journal Title
  
  Cerebral Cortex
  
  Volume: [Epub ahead of print] Issue: 11 Pages: 4111-4125
- DOI
  10.1093/cercor/bhu129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25650086, KAKENHI-PROJECT-15K14323, KAKENHI-PLANNED-22115009, KAKENHI-PUBLICLY-15H01453, KAKENHI-PROJECT-25430045, KAKENHI-PROJECT-25290010
[Journal Article] Transcallosal projections require glycoprotein M6-dependent neurite growth and guidance2014
- Author(s)
  Mita S, de Monasterio-Schrader P, Fünfschilling U, Kawasaki T, Mizuno H, Iwasato T, Nave K-A, Werner HB, and Hirata T
- Journal Title
  
  Cerebral Cortex
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22115009
[Journal Article] NMDAR-Regulated Dynamics of Layer 4 Neuronal Dendrites during Thalamocortical Reorganization in Neonates.2014
- Author(s)
  Hidenobu Mizuno, Wenshu Luo, Etsuko Tarusawa, Yoshikazu M. Saito, Takuya Sato, Yumiko Yoshimura,Shigeyoshi Itohara, Takuji Iwasato
- Journal Title
  
  Neuron
  
  Volume: Vol. 82(2) Issue: 2 Pages: 365-379
- DOI
  10.1016/j.neuron.2014.02.026
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J05789, KAKENHI-PLANNED-22115009, KAKENHI-PROJECT-25640015
[Presentation] 網膜微小血管とその内腔を流れる血流の高解像度生体イメージングを用いた、リパスジル点眼による網膜循環への作用の検討2024
- Author(s)
  下田健文、瀧原祐史、檜垣匠、小島祥、藤本智和、水野秀信、井上俊洋
- Organizer
  第１回 ROCK Ocular Conference
- Data Source
  KAKENHI-PROJECT-23K09062
[Presentation] 大脳皮質における神経回路形成と同期的自発神経活動の連関2024
- Author(s)
  水野秀信
- Organizer
  Neuro2024 [シンポジウム：4S01m] 神経脳多元自発活動の創発と遷移による脳のデザインビルド（シンポジウムオーガナイザー兼任）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K03266
[Presentation] 大脳皮質における神経回路形成と同期的自発神経活動の連関2024
- Author(s)
  水野秀信
- Organizer
  Neuro2024 [シンポジウム：4S01m] 神経脳多元自発活動の創発と遷移による脳のデザインビルド（シンポジウムオーガナイザー兼任）
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05094
[Presentation] Spontaneous neuronal activity and the formation of cortical microcircuits2023
- Author(s)
  Hidenobu Mizuno
- Organizer
  第38回熊本医学・生物科学国際シンポジウム「機能的脳神経回路システムの構築メカニズム」
- Data Source
  KAKENHI-PLANNED-22H05094
[Presentation] 大脳皮質神経回路形成の生体2光子イメージング2022
- Author(s)
  水野秀信
- Organizer
  第64回日本顕微鏡学会九州支部集会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06876
[Presentation] 大脳皮質神経回路形成の生体2光子イメージング2022
- Author(s)
  水野秀信
- Organizer
  第64回日本顕微鏡学会九州支部集会学術講演会
- Invited
- Data Source
  KAKENHI-PLANNED-22H05094
[Presentation] 脳梁投射軸索の発達ダイナミクスのタイムラプス・イメージング2021
- Author(s)
  中川直, 水野秀信, 田川義晃
- Organizer
  第44回日本神経科学大会／第1回CJK国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06887
[Presentation] 発達期大脳皮質第4層における神経細胞動態と活動様式のイメージング（兼シンポジウムオーガナイザー）2021
- Author(s)
  水野秀信
- Organizer
  第44回日本神経科学大会 [1S02a] 神経活動依存的なネットワーク形成：細胞間コミュニケーションから細胞内分子シグナルまで
- Data Source
  KAKENHI-PROJECT-20K06876
[Presentation] Role of Ras-GAP During Neuronal Circuit Development in the Barrel Cortex Layer IV2021
- Author(s)
  Madhura Subba Rao, Hiromi Mizuno, Takuya Sato, Takuji Iwasato, Hidenobu Mizuno
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K06876
[Presentation] Time-lapse imaging of callosal axon projection dynamics in vivo2020
- Author(s)
  中川直,　水野秀信,　田川義晃
- Organizer
  西日本生理学会
- Data Source
  KAKENHI-PROJECT-19K06887
[Presentation] Patchwork-type spontaneous activity in developing neocortex2019
- Author(s)
  Hidenobu Mizuno
- Organizer
  京都大学・iCeMS: International conference on interdisciplinary life sciences
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] Elucidating the mechanisms for activity-dependent neuronal circuit formation by in vivo imaging2019
- Author(s)
  Hidenobu Mizuno
- Organizer
  Korea Advanced Institute for Science and Technology (KAIST), Daejeon, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo imaging of the developing cerebral cortex to elucidate the mechanisms for activity-dependent circuit formation2019
- Author(s)
  Hidenobu Mizuno
- Organizer
  九州大学・医学研究院
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo imaging of the developing cerebral cortex to elucidate the mechanism for activity-dependent circuit maturation2019
- Author(s)
  Hidenobu Mizuno
- Organizer
  IBRO 2019 (The 10th IBRO World congress of Neuroscience): Symposium (Development and plasticity of brain connectivity)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] ミクロとマクロの生体同時イメージングを目指して2018
- Author(s)
  水野秀信
- Organizer
  新潟大学脳研究所・新潟脳神経研究会特別例会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo imaging of the developing cerebral cortex to elucidate the mechanism of circuit refinement2018
- Author(s)
  Hidenobu Mizuno
- Organizer
  University of Zurich, Brain Research Institute, Zurich, Switzerland
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] 生体マルチスケールイメージングによる脳神経回路形成機構の解明2018
- Author(s)
  水野秀信
- Organizer
  大阪大学・Frontier Bioscience Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo two-photon imaging of developing neuronal circuits in the cerebral cortex2018
- Author(s)
  Hidenobu Mizuno
- Organizer
  KU-KAIST Joint Symposium, Daejeon, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] 生体イメージングによる発達期の脳神経回路形成機構の解明2017
- Author(s)
  水野秀信
- Organizer
  新潟大学脳研究所・新潟脳神経研究会特別例会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo imaging of the developing mouse somatosensory cortex for elucidating the mechanism of neuronal circuit refinement2017
- Author(s)
  Hidenobu Mizuno
- Organizer
  Circuit construction in the mammalian brain, NIG symposium
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] 発達期脳の生体イメージングによる、脳神経回路形成と脳病態の解明2017
- Author(s)
  水野秀信
- Organizer
  熊本大学第14回生命資源研究・支援センターシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] Imaging the mouse barrel cortex in vivo to analyze the mechanism of cortical circuit2017
- Author(s)
  Hidenobu Mizuno
- Organizer
  National Taiwan University main campus
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo 2-photon imaging of neuronal activity in developing cerebral cortex2017
- Author(s)
  Hidenobu Mizuno
- Organizer
  National Taiwan University medical campus
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo 2-photon imaging of neuronal activity in layer 4 of the neonatal somatosensory cortex2016
- Author(s)
  H. MIZUNO, T. SATO, T. IWASATO
- Organizer
  Cell symposia
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo 2-photon imaging of neuronal activity in layer 4 of the neonatal barrel cortex2016
- Author(s)
  H. MIZUNO, T. SATO, T. IWASATO
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo 2-photon imaging in layer 4 of the neonatal barrel cortex2016
- Author(s)
  H. Mizuno, T. Sato, T. Iwasato
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14322
[Presentation] ミクロとマクロのイメージングの統合による新分野の開拓2016
- Author(s)
  水野秀信　（兼シンポジウム企画者）
- Organizer
  日本発生生物学会秋季シンポジウム2016
- Place of Presentation
  静岡県三島市
- Year and Date
  2016-10-19
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] ミクロとマクロのイメージングの統合による新分野の開拓2016
- Author(s)
  水野秀信（兼シンポジウム企画者）
- Organizer
  日本発生生物学会　秋季シンポジウム2016
- Place of Presentation
  静岡県三島市
- Year and Date
  2016-10-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K14322
[Presentation] In vivo 2-photon imaging in layer 4 of the neonatal somatosensory cortex2016
- Author(s)
  H. Mizuno, T. Sato, T. Iwasato
- Organizer
  Cell symposia
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14322
[Presentation] 新生仔大脳皮質第4層におけるポピュレーション活動の2光子イメージング2015
- Author(s)
  水野秀信、中沢信吾、佐藤拓也、岩里琢冶
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸市
- Year and Date
  2015-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14322
[Presentation] 神経活動依存的な大脳皮質神経回路形成の生体イメージング2014
- Author(s)
  水野秀信
- Organizer
  京都大学大学院生物物理学教室「生物物理学セミナー」
- Place of Presentation
  京都大学理学研究科、京都市
- Year and Date
  2014-11-10
- Invited
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] NMDAR-regulated dynamics of layer 4 neuronal dendrites during thalamocortical reorganization in neonates2014
- Author(s)
  Mizuno,H., Iwasato,T.
- Organizer
  国際高等研究所研究プロジェクト「ゲノム工学とイメージングサイエンスに基づく生命システム研究の新展開」
- Place of Presentation
  Kyoto, Japan
- Invited
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] Refinement of barrel cell dendrites in neonatal mouse somatosensory cortex2013
- Author(s)
  Mizuno,H., Luo,W., Saito,Y.M., Itohara,S., Iwasato,T.
- Organizer
  国際シンポジウム「感覚受容と神経回路」
- Place of Presentation
  東京
- Year and Date
  2013-02-11
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] 新生仔マウス体性感覚野におけるバレル細胞樹状突起の精緻化過程とNMDAR の2012
- Author(s)
  水野秀信，岩里琢治
- Organizer
  2012年度　包括脳ネットワーク夏のワークショップ
- Place of Presentation
  宮城県仙台市
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] In vivo 2-photon imaging of neonatal cortex reveals NMDA receptor-dependent refinement of barrel cell dendrites2012
- Author(s)
  Mizuno,H., Luo,W., Saito,Y.M., Itohara,S., Iwasato,T.
- Organizer
  遺伝研研究会　Circuit construction in the mammalian cerebral cortex : Genetic and imaging approaches
- Place of Presentation
  静岡県三島市
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] The RacGAP a2-chimerin functions during development to establish normal hippocampus-dependent learning in adulthood2012
- Author(s)
  Iwata,R., Mizuno,H., Iwama,M., Goto,H., Tanaka,M., Itohara,S., Iwasato,T.
- Organizer
  Society for Neuroscience 2012 MCCS
- Place of Presentation
  アメリカ合衆国ワシントンDC
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] The RacGAP α2-chimerin acts during development to establish normal hippocampus-dependent learning in adulthood2012
- Author(s)
  Iwata,R., Mizuno,H., Iwama,M., Goto,H., Tanaka,M., Itohara,S., Iwasato,T.
- Organizer
  遺伝研研究会　Circuit construction in the mammalian cerebral cortex : Genetic and imaging approaches
- Place of Presentation
  静岡県三島市
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] Direct analyses of NMDA receptor-mediated refinement of barrel neuron dendrites in neonatal mouse somatosensory cortex2012
- Author(s)
  Mizuno,H., Luo,W., Saito,Y.M., Itohara,S., Iwasato,T.
- Organizer
  Society for Neuroscience 2012
- Place of Presentation
  アメリカ合衆国ワシントンDC
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] Differential roles of Rac-GAP α-chimerin isoforms in cognitive function and neuronal morphogenesis2012
- Author(s)
  Iwata,R., Mizuno,H., Iwama,M., Goto,H., Tanaka,M., Itohara,S., Iwasato,T.
- Organizer
  Society for Neuroscience 2012
- Place of Presentation
  アメリカ合衆国ワシントンDC
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] Single cell labeling method reveals the precise developmental process of barrel neuron dendrites in somatosensory cortex of neonatal mice2011
- Author(s)
  水野秀信, 齊藤芳和, 糸原重美, 岩里琢治
- Organizer
  Neuroscience 2011, Society for Neuroscience 41st annual meeting
- Place of Presentation
  Washington D.C.
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] 高輝度単一細胞標識法による幼仔期体性感覚野におけるバレル細胞樹状突起の詳細な発達過程の解析2011
- Author(s)
  Mizuno H, Saito YM Itohara S, Iwasato T.
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22700347
[Presentation] Single cell labeling method reveals the precise developmental process of barrel neuron dendrites in somatosensory cortex of neonatal mice2011
- Author(s)
  水野秀信
- Organizer
  Neuroscience 2011
- Place of Presentation
  ワシントンDCアメリカ合衆国
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22700347
[Presentation] 高輝度単一細胞標識法による幼仔期体性感覚野におけるバレル細胞2011
- Author(s)
  水野秀信, 齊藤芳和, 糸原重美, 岩里琢治
- Organizer
  Neuroscience2011(第34回日本神経科学大会)
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] Single cell labeling method reveals the precise developmental process of barrel neuron dendrites in somatosensory cortex of neonatal mice2011
- Author(s)
  Mizuno H, Saito YM, Itohara S, Iwasato T.
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22700347
[Presentation] NMDAR-regulated fluctuating dynamics in refinement of barrel cell dendrites
- Author(s)
  H. MIZUNO, W. LUO, Y. M. SAITO, S. ITOHARA, T. IWASATO
- Organizer
  Cell symposia CSFN2013
- Place of Presentation
  サンディエゴ、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] 哺乳類大脳皮質神経回路形成の生体イメージング
- Author(s)
  水野秀信
- Organizer
  遺伝研研究会「哺乳類脳の機能的神経回路の構築メカニズム」
- Place of Presentation
  国立遺伝学研究所、三島市
- Year and Date
  2014-12-01 – 2014-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] In vivo imaging of dendritic refinement of barrel cells in neonatal cortex
- Author(s)
  H. MIZUNO, W. LUO, Y. M. SAITO, S. ITOHARA, T. IWASATO
- Organizer
  北米神経科学学会 SfN2013
- Place of Presentation
  サンディエゴ、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] NMDAR-regulated fluctuating dynamics in refinement of barrel cell dendrites
- Author(s)
  Mizuno,H.,Luo,W.,Saito,Y.M.,Itohara,S.,Iwasato,T.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] NMDAR-REGULATED DYNAMICS OF LAYER 4 NEURONAL DENDRITES DURING THALAMOCORTICAL REORGANIZATION IN NEONATES
- Author(s)
  H. Mizuno, W. Luo, E. Tarusawa, Y.M. Saito, T. Sato, Y. Yoshimura, S. Itohara, T. Iwasato
- Organizer
  9th FENS Forum of Neuroscience
- Place of Presentation
  Milan, Itary
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] RacGAP α2-chimaerin regulates developmental spine elimination to establish normal hippocampus-dependent learning
- Author(s)
  Iwata,R.,Ohi,K.,Matsukawa,H.,Kobayashi,Y.,Masuda,A.,Mizuno,H.,Iwama,M.,Goto,H.,Yamamori,H.,Yuka,Y.,Tanaka,M.,Hashimoto,R.,Itohara,S.,Iwasato,T.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] NMDAR-regulated dynamics of layer 4 neuronal dendrites during thalamocortical reorganization in neonates
- Author(s)
  Hidenobu Mizuno and Takuji Iwasato
- Organizer
  高等研プロジェクト「ゲノム工学とイメージングサイエンスに基づく生命システム研究の新展開」
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] Activity-dependent dendritic refinement and cell patterning of barrel cells in the early postnatal mouse somatosensory cortex
- Author(s)
  Luo,W.,Mizuno,H.,Itohara,S.,Iwasato,T.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] In vivo imaging of NMDAR-dependent dendritic refinement of barrel cells in neonatal somatosensory cortex
- Author(s)
  Hidenobu Mizuno, Wenshu Luo, Yoshikazu M. Saito, Shigeyoshi Itohara, Takuji Iwasato
- Organizer
  日本神経科学大会　Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25640015

1. Tamagawa Nao (20611065)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. Takihara Yuji (50640140)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 井上俊洋 (00317025)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. Iwasato Takuji (00311332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
5. Sada Aiko (80779059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Uesaka Naofumi (70597624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 高橋枝里 (60622602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 泉健次 (80242436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 柳沢裕美 (40746301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 神戸悠輝 (60549913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 早川隆 (30756789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 千葉逸人 (70571793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 梅本晃正 (50620225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 有馬勇一郎 (60706414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 池内与志穂 (30740097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 中川直

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
17. 横溝智雅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 小島祥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 平田たつみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hidenobu Mizuno 水野 秀信

MIZUNO Hidenobu 水野 秀信

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生体光遺伝学を用いた同期的神経活動の誘発による脳回路発達の改善Principal Investigator

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The relationship between spontaneous activity and circuit formation in the cerebral cortexPrincipal Investigator

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In vivo imaging of neonatal brain to elucidate the role of spontaneous synchronous activity in cortical circuit formationPrincipal Investigator

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In vivo imaging of neonatal brain to elcidate the mechanism of activity-dependent thalamocortical circuit formationPrincipal Investigator

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In vivo imaging of neuronal activity in the developing cerebral cortexPrincipal Investigator

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In vivo 2-photon imaging of the cerebral cortex in neonatal micePrincipal Investigator

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Analyses of mechanism for neuronal circuit refinement in barrel cortex by mouse genetics and electroporation methodPrincipal Investigator

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Hidenobu Mizuno 水野秀信

MIZUNO Hidenobu 水野秀信

[Book] 神経回路の形成機構：哺乳類大脳皮質神経回路の生後発達再生医療シリーズ　脳神経系の再生医学、高橋惇・井村裕夫監、河崎洋志編2015