MIZUNO Hidenobu 水野秀信

Researcher Number	00567159
Other IDs
Affiliation *help	2013 – 2017 : 国立遺伝学研究所, 個体遺伝研究系, 助教 2013 : 国立遺伝学研究所, 大学共同利用機関等の部局等, 助教 2010 – 2011 : National Institute of Genetics, 助教 2009 – 2011 : 国立遺伝学研究所, 個体遺伝研究系, 助教
Review Section/Research Field	Principal Investigator Neurophysiology / General neuroscience / Neuroscience in general Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 大脳皮質 / 神経科学 / 2光子イメージング / 生体イメージング / 神経回路形成 / 生理学 / バレル / 二光子顕微鏡 / 臨界期 / 2光子顕微鏡 … More Except Principal Investigator 脳・神経 / 体性感覚系 / 遺伝学 / 遺伝子 / イメージング / マウス / 発達期可塑性 / 発生・分化 / 発達 / ノックアウト / 神経科学 / 遺伝子ノックアウト / 神経回路 Less

新生仔脳深部の生体イメージングによる活動依存的な視床皮質回路形成の包括的解析Principal InvestigatorOngoing
- Principal Investigator
  
  水野秀信
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Institute of Genetics
In vivo imaging of neuronal activity in the developing cerebral cortexPrincipal Investigator
- Principal Investigator
  
  Mizuno Hidenobu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Institute of Genetics
In vivo 2-photon imaging of the cerebral cortex in neonatal micePrincipal Investigator
- Principal Investigator
  
  MIZUNO Hidenobu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Institute of Genetics
Analyses of mechanism for neuronal circuit refinement in barrel cortex by mouse genetics and electroporation methodPrincipal Investigator
- Principal Investigator
  
  MIZUNO Hidenobu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  National Institute of Genetics
Circuit remodeling during postnatal development in the mouse somatosensory cortex
- Principal Investigator
  
  Iwasato Takuji
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics

All 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 神経回路の形成機構：哺乳類大脳皮質神経回路の生後発達再生医療シリーズ　脳神経系の再生医学、高橋惇・井村裕夫監、河崎洋志編2015
- Author(s)
  岩里琢治，水野秀信
- Total Pages
  169
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25640015
[Book] 脳神経系の発生・再生の融合的新展開（分担執筆）2014
- Author(s)
  岩里琢治、水野秀信
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PLANNED-22115009
[Journal Article] Supernova: A Versatile Vector System for Single-Cell Labeling and Gene Function Studies in vivo.2016
- Author(s)
  Luo, W., Mizuno, H., Iwata, R., Nakazawa, S., Yasuda, K., Itohara, S., Iwasato, T.
- Journal Title
  
  Sci Rep.
  
  Volume : 6 Pages : 35747-35747
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04263, KAKENHI-PROJECT-16H06143, KAKENHI-PROJECT-15J03643, KAKENHI-PROJECT-15K14322, KAKENHI-PROJECT-16K14559
[Journal Article] Developmental RacGAPa 2-chimaerin signaling is a determinant of the morphological features of dendritic spines in adulthood.2015
- Author(s)
  .Iwata, R., Matsukawa, H., Yasuda, K., Mizuno, H., Itohara, S., Iwasato, T.
- Journal Title
  
  J. Nerurosci.
  
  Volume : 35 Pages : 13728-13744
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22115009, KAKENHI-PROJECT-15H04290, KAKENHI-PUBLICLY-15H01454, KAKENHI-PROJECT-15H04263
[Journal Article] Developmental RacGAP α2-chimaerin signaling is a determinant of the morphological features of dendritic spines in adulthood.2015
- Author(s)
  Ryohei Iwata, Hiroshi Matsukawa, Kosuke Yasuda, Hidenobu Mizuno, Shigeyoshi Itohara, Takuji Iwasato
- Journal Title
  
  The Journal of Neuroscience
  
  Volume : 35 Pages : 13728-13744
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14322
[Journal Article] Transcallosal projections require glycoprotein M6-dependent neurite growth and guidance.2015
- Author(s)
  S. Mita, P. Monasterio-Schrader, U. Funfschilling, T. Kawasaki, H. Mizuno, T. Iwasato, K.-A. Nave, H. B. Werner, and T. Hirata
- Journal Title
  
  Cerebral Cortex
  
  Volume : 25 Pages : 4111-4125
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14323, KAKENHI-PLANNED-22115009, KAKENHI-PUBLICLY-15H01453, KAKENHI-PROJECT-25430045, KAKENHI-PROJECT-25290010, KAKENHI-PROJECT-25650086
[Journal Article] Transcallosal projections require glycoprotein M6-dependent neurite growth and guidance2014
- Author(s)
  Mita S, de Monasterio-Schrader P, Fünfschilling U, Kawasaki T, Mizuno H, Iwasato T, Nave K-A, Werner HB, and Hirata T
- Journal Title
  
  Cerebral Cortex
  
  Volume : in press
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22115009
[Journal Article] NMDAR-Regulated Dynamics of Layer 4 Neuronal Dendrites during Thalamocortical Reorganization in Neonates.2014
- Author(s)
  Mizuno H, Luo W, Tarusawa E, Saito YM, Sato T, Yoshimura Y, Itohara S, Iwasato T.
- Journal Title
  
  Neuron
  
  Volume : 82 Pages : 365-379
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22115009, KAKENHI-PROJECT-25640015, KAKENHI-PROJECT-13J05789
[Presentation] In vivo 2-photon imaging of neuronal activity in layer 4 of the neonatal barrel cortex2016
- Author(s)
  H. MIZUNO, T. SATO, T. IWASATO
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] ミクロとマクロのイメージングの統合による新分野の開拓2016
- Author(s)
  水野秀信　（兼シンポジウム企画者）
- Organizer
  日本発生生物学会秋季シンポジウム2016
- Place of Presentation
  静岡県三島市
- Year and Date
  2016-10-19
- Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo 2-photon imaging of neuronal activity in layer 4 of the neonatal somatosensory cortex2016
- Author(s)
  H. MIZUNO, T. SATO, T. IWASATO
- Organizer
  Cell symposia
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-10
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-16H06143
[Presentation] In vivo 2-photon imaging in layer 4 of the neonatal barrel cortex2016
- Author(s)
  H. Mizuno, T. Sato, T. Iwasato
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14322
[Presentation] ミクロとマクロのイメージングの統合による新分野の開拓2016
- Author(s)
  水野秀信（兼シンポジウム企画者）
- Organizer
  日本発生生物学会　秋季シンポジウム2016
- Place of Presentation
  静岡県三島市
- Year and Date
  2016-10-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K14322
[Presentation] In vivo 2-photon imaging in layer 4 of the neonatal somatosensory cortex2016
- Author(s)
  H. Mizuno, T. Sato, T. Iwasato
- Organizer
  Cell symposia
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-10
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K14322
[Presentation] 新生仔大脳皮質第4層におけるポピュレーション活動の2光子イメージング2015
- Author(s)
  水野秀信、中沢信吾、佐藤拓也、岩里琢冶
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸市
- Year and Date
  2015-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14322
[Presentation] NMDAR-regulated dynamics of layer 4 neuronal dendrites during thalamocortical reorganization in neonates2014
- Author(s)
  Mizuno,H., Iwasato,T.
- Organizer
  国際高等研究所研究プロジェクト「ゲノム工学とイメージングサイエンスに基づく生命システム研究の新展開」
- Place of Presentation
  Kyoto, Japan
- Invited
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] 神経活動依存的な大脳皮質神経回路形成の生体イメージング2014
- Author(s)
  水野秀信
- Organizer
  京都大学大学院生物物理学教室「生物物理学セミナー」
- Place of Presentation
  京都大学理学研究科、京都市
- Year and Date
  2014-11-10
- Invited
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] Refinement of barrel cell dendrites in neonatal mouse somatosensory cortex2013
- Author(s)
  Mizuno,H., Luo,W., Saito,Y.M., Itohara,S., Iwasato,T.
- Organizer
  国際シンポジウム「感覚受容と神経回路」
- Place of Presentation
  東京
- Year and Date
  2013-02-11
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] The RacGAP α2-chimerin acts during development to establish normal hippocampus-dependent learning in adulthood2012
- Author(s)
  Iwata,R., Mizuno,H., Iwama,M., Goto,H., Tanaka,M., Itohara,S., Iwasato,T.
- Organizer
  遺伝研研究会　Circuit construction in the mammalian cerebral cortex : Genetic and imaging approaches
- Place of Presentation
  静岡県三島市
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] In vivo 2-photon imaging of neonatal cortex reveals NMDA receptor-dependent refinement of barrel cell dendrites2012
- Author(s)
  Mizuno,H., Luo,W., Saito,Y.M., Itohara,S., Iwasato,T.
- Organizer
  遺伝研研究会　Circuit construction in the mammalian cerebral cortex : Genetic and imaging approaches
- Place of Presentation
  静岡県三島市
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] Direct analyses of NMDA receptor-mediated refinement of barrel neuron dendrites in neonatal mouse somatosensory cortex2012
- Author(s)
  Mizuno,H., Luo,W., Saito,Y.M., Itohara,S., Iwasato,T.
- Organizer
  Society for Neuroscience 2012
- Place of Presentation
  アメリカ合衆国ワシントンDC
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] Differential roles of Rac-GAP α-chimerin isoforms in cognitive function and neuronal morphogenesis2012
- Author(s)
  Iwata,R., Mizuno,H., Iwama,M., Goto,H., Tanaka,M., Itohara,S., Iwasato,T.
- Organizer
  Society for Neuroscience 2012
- Place of Presentation
  アメリカ合衆国ワシントンDC
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] 新生仔マウス体性感覚野におけるバレル細胞樹状突起の精緻化過程とNMDAR の2012
- Author(s)
  水野秀信，岩里琢治
- Organizer
  2012年度　包括脳ネットワーク夏のワークショップ
- Place of Presentation
  宮城県仙台市
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] 幼仔期体性感覚野におけるNMDA受容体依存的なバレル細胞樹状突起の精緻化　NMDA receptor-dependent refinement of barrel cell dendrite in the neonatal mouse somatosensory cortex2012
- Author(s)
  水野秀信，齊藤芳和，糸原重美，岩里琢治
- Organizer
  第35回　日本神経科学大会（Neuroscience 2012）
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] The RacGAP a2-chimerin functions during development to establish normal hippocampus-dependent learning in adulthood2012
- Author(s)
  Iwata,R., Mizuno,H., Iwama,M., Goto,H., Tanaka,M., Itohara,S., Iwasato,T.
- Organizer
  Society for Neuroscience 2012 MCCS
- Place of Presentation
  アメリカ合衆国ワシントンDC
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] Single cell labeling method reveals the precise developmental process of barrel neuron dendrites in somatosensory cortex of neonatal mice2011
- Author(s)
  水野秀信
- Organizer
  Neuroscience 2011
- Place of Presentation
  ワシントンDCアメリカ合衆国
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22700347
[Presentation] 高輝度単一細胞標識法による幼仔期体性感覚野におけるバレル細胞2011
- Author(s)
  水野秀信, 齊藤芳和, 糸原重美, 岩里琢治
- Organizer
  Neuroscience2011(第34回日本神経科学大会)
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] Single cell labeling method reveals the precise developmental process of barrel neuron dendrites in somatosensory cortex of neonatal mice2011
- Author(s)
  水野秀信, 齊藤芳和, 糸原重美, 岩里琢治
- Organizer
  Neuroscience 2011, Society for Neuroscience 41st annual meeting
- Place of Presentation
  Washington D.C.
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] 高輝度単一細胞標識法による幼仔期体性感覚野におけるバレル細胞樹状突起の詳細な発達過程の解析2011
- Author(s)
  Mizuno H, Saito YM Itohara S, Iwasato T.
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22700347
[Presentation] Single cell labeling method reveals the precise developmental process of barrel neuron dendrites in somatosensory cortex of neonatal mice2011
- Author(s)
  Mizuno H, Saito YM, Itohara S, Iwasato T.
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22700347
[Presentation] 高輝度単一細胞標識法による幼仔期体性感覚野におけるバレル細胞樹状突起の詳細な発達過程の解析2011
- Author(s)
  水野秀信
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22700347
[Presentation] In vivo imaging of dendritic refinement of barrel cells in neonatal cortex
- Author(s)
  H. MIZUNO, W. LUO, Y. M. SAITO, S. ITOHARA, T. IWASATO
- Organizer
  北米神経科学学会 SfN2013
- Place of Presentation
  サンディエゴ、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] In vivo imaging of NMDAR-dependent dendritic refinement of barrel cells in neonatal somatosensory cortex
- Author(s)
  Hidenobu Mizuno, Wenshu Luo, Yoshikazu M. Saito, Shigeyoshi Itohara, Takuji Iwasato
- Organizer
  日本神経科学大会　Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] NMDAR-regulated dynamics of layer 4 neuronal dendrites during thalamocortical reorganization in neonates
- Author(s)
  Hidenobu Mizuno and Takuji Iwasato
- Organizer
  高等研プロジェクト「ゲノム工学とイメージングサイエンスに基づく生命システム研究の新展開」
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] Activity-dependent dendritic refinement and cell patterning of barrel cells in the early postnatal mouse somatosensory cortex
- Author(s)
  Luo,W.,Mizuno,H.,Itohara,S.,Iwasato,T.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] RacGAP α2-chimaerin regulates developmental spine elimination to establish normal hippocampus-dependent learning
- Author(s)
  Iwata,R.,Ohi,K.,Matsukawa,H.,Kobayashi,Y.,Masuda,A.,Mizuno,H.,Iwama,M.,Goto,H.,Yamamori,H.,Yuka,Y.,Tanaka,M.,Hashimoto,R.,Itohara,S.,Iwasato,T.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] NMDAR-regulated fluctuating dynamics in refinement of barrel cell dendrites
- Author(s)
  Mizuno,H.,Luo,W.,Saito,Y.M.,Itohara,S.,Iwasato,T.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-22115009
[Presentation] 哺乳類大脳皮質神経回路形成の生体イメージング
- Author(s)
  水野秀信
- Organizer
  遺伝研研究会「哺乳類脳の機能的神経回路の構築メカニズム」
- Place of Presentation
  国立遺伝学研究所、三島市
- Year and Date
  2014-12-01 – 2014-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] NMDAR-REGULATED DYNAMICS OF LAYER 4 NEURONAL DENDRITES DURING THALAMOCORTICAL REORGANIZATION IN NEONATES
- Author(s)
  H. Mizuno, W. Luo, E. Tarusawa, Y.M. Saito, T. Sato, Y. Yoshimura, S. Itohara, T. Iwasato
- Organizer
  9th FENS Forum of Neuroscience
- Place of Presentation
  Milan, Itary
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-25640015
[Presentation] NMDAR-regulated fluctuating dynamics in refinement of barrel cell dendrites
- Author(s)
  H. MIZUNO, W. LUO, Y. M. SAITO, S. ITOHARA, T. IWASATO
- Organizer
  Cell symposia CSFN2013
- Place of Presentation
  サンディエゴ、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-25640015

1. Iwasato Takuji (00311332)

# of Collaborated Projects : 1results

# of Collaborated Products : 20results
2. Hirata Tatsumi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
3. KAWASAKI Takahiko

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
4. 糸原重美

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

MIZUNO Hidenobu 水野 秀信

Research Projects

Research Products

Co-Researchers

新生仔脳深部の生体イメージングによる活動依存的な視床皮質回路形成の包括的解析Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vivo imaging of neuronal activity in the developing cerebral cortexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vivo 2-photon imaging of the cerebral cortex in neonatal micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of mechanism for neuronal circuit refinement in barrel cortex by mouse genetics and electroporation methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Circuit remodeling during postnatal development in the mouse somatosensory cortex

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 神経回路の形成機構：哺乳類大脳皮質神経回路の生後発達 再生医療シリーズ 脳神経系の再生医学、高橋惇・井村裕夫監、河崎洋志編2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 脳神経系の発生・再生の融合的新展開（分担執筆）2014

Author(s)

Publisher

Data Source

[Journal Article] Supernova: A Versatile Vector System for Single-Cell Labeling and Gene Function Studies in vivo.2016

Author(s)

Journal Title

Data Source

[Journal Article] Developmental RacGAPa 2-chimaerin signaling is a determinant of the morphological features of dendritic spines in adulthood.2015

Author(s)

Journal Title

Data Source

[Journal Article] Developmental RacGAP α2-chimaerin signaling is a determinant of the morphological features of dendritic spines in adulthood.2015

Author(s)

Journal Title

Data Source

[Journal Article] Transcallosal projections require glycoprotein M6-dependent neurite growth and guidance.2015

Author(s)

Journal Title

Data Source

[Journal Article] Transcallosal projections require glycoprotein M6-dependent neurite growth and guidance2014

Author(s)

Journal Title

Data Source

[Journal Article] NMDAR-Regulated Dynamics of Layer 4 Neuronal Dendrites during Thalamocortical Reorganization in Neonates.2014

Author(s)

Journal Title

Data Source

[Presentation] In vivo 2-photon imaging of neuronal activity in layer 4 of the neonatal barrel cortex2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ミクロとマクロのイメージングの統合による新分野の開拓2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] In vivo 2-photon imaging of neuronal activity in layer 4 of the neonatal somatosensory cortex2016

MIZUNO Hidenobu 水野秀信

[Book] 神経回路の形成機構：哺乳類大脳皮質神経回路の生後発達再生医療シリーズ　脳神経系の再生医学、高橋惇・井村裕夫監、河崎洋志編2015