Sakai Kenji 坂井健二

Researcher Number	00572306
Other IDs
Affiliation *help	2016 – 2018 : 金沢大学, 附属病院, 助教 2014 – 2015 : 金沢大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Human pathology Except Principal Investigator Neurology
Keywords	Principal Investigator 脳アミロイドアンギオパチー / 遺伝子多型 / 炎症 Except Principal Investigator アミロイドβ蛋白 / アミロイドβタンパク / 凝集 / アルツハイマー病 / 伝播 / 防御

Study on transmission of Abeta aggregates and its preventionOngoing
- Principal Investigator
  
  山田正仁
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Pathomechanisms of cerebral amyloid angiopathy-related inflammationPrincipal Investigator
- Principal Investigator
  
  Sakai Kenji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kanazawa University

All 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Cerebral amyloid angiopathy-related microbleeds and CSF biomarkers in Alzheimer’s disease2017
- Author(s)
  Noguchi-Shinohara M, Komatsu J, Samuraki M, Matsunari I, Ikeda T, Sakai K, Hamaguchi T, Ono K, Nakamura H, Yamada M.
- Journal Title
  
  J Alzheimers Dis
  
  Volume : 55 Pages : 905-913
- DOI
  10.3233/JAD-160651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-26860234
[Journal Article] Quantification of molecular interactions between apoE, amyloid-beta (Aβ) and laminin: relevance to accumulation of Aβ in Alzheimer’s disease2016
- Author(s)
  Zekonyte J, Sakai K, Nicoll JAR, Weller RO, Carare RO
- Journal Title
  
  Biochim Biophys Acta
  
  Volume : 1862 Issue : 5 Pages : 1047-1053
- Publisher
  Elsevier
- DOI
  10.1016/j.bbadis.2015.08.025
- Year and Date
  2016-05-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860234
[Journal Article] Significant association of cadaveric dura mater grafting with subpial Aβ deposition and meningeal amyloid angiopathy2016
- Author(s)
  Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H, Yamada M.
- Journal Title
  
  Acta Neuropathol
  
  Volume : 132(2) Pages : 313-5
- DOI
  10.1007/s00401-016-1588-3
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25257506, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-26430060, KAKENHI-PROJECT-26860234, KAKENHI-PROJECT-15K08369, KAKENHI-PROJECT-16H06277
[Journal Article] Aβ immunotherapy for Alzheimer's disease: effects on apoE and cerebral vasculopathy2014
- Author(s)
  Kenji Sakai, Delphine Boche, Roxana Carare, David Johnston, Clive Holmes, Seth Love, James AR Nicoll
- Journal Title
  
  Acta Neuropathologica
  
  Volume : 128 Pages : 777-789
- DOI
  10.1007/s00401-014-1340-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860234
[Presentation] Iatrogenic Creutzfeldt-Jakob disease related to dura mater grafts2017
- Author(s)
  Yamada M, Hamaguchi T, Sakai K, Noguchi-Shinohara M, Nozaki I, Taniguchi Y, Kobayashi A, Takeuchi A, Kitamoto T, Nakamura Y, Sanjo N, Tsukamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Mizusawa H
- Organizer
  PRION2017
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-17H04194
[Presentation] Possible human-to-human transmission of cerebral β-amyloidosis via cadaveric dura mater grafting2017
- Author(s)
  Yamada M, Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H
- Organizer
  Alzheimer's Association International Conference (AAIC) 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04194
[Presentation] Aquaporin 4 and the response to Aβ immunotherapy in human Alzheimer’s disease2016
- Author(s)
  Sakai K, Boche D, Johnston D, Holmes C, Love S, Nicoll J
- Organizer
  5th International CAA Conference
- Place of Presentation
  Boston
- Year and Date
  2016-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860234
[Presentation] Aβ immunothreapy for Alzheimer’s disease: effects on apolipoprotein E and cerebral vasculature2015
- Author(s)
  Sakai K, Boche D, Carare R, Johnston D, Holmes C, Love S, Nicoll J
- Organizer
  7th World Congress of the International Society for Vascular Behavioural and Cognitive Disorders (Vas-Cog2015 Tokyo)
- Place of Presentation
  Tokyo Fashion Town, Tokyo
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860234
[Presentation] Aβ immunotherapy for Alzheimer’s disease: effects on apoE and cerebral vasculopathy
- Author(s)
  Kenji Sakai, Delphine Boche, Roxana Carare, David Johnston, Clive Holmes, Seth Love, James Nicoll
- Organizer
  第55回日本神経学会総会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26860234

1. 山田正仁 (80191336)

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
2. 濱口毅 (70452109)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
3. 池田篤平 (30755773)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. 中山隆宏 (00532821)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. Ono Kenjiro

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
6. 北本哲之

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
7. 内木宏延

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
8. 高尾昌樹

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
9. 岩崎靖

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
10. 鈴木貞夫

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
11. 喜多義邦

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. 鈴木康司

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. 村山繁雄

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
14. 清水厚志

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
15. 高橋隆

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

Sakai Kenji 坂井 健二

Research Projects

Research Products

Co-Researchers

Study on transmission of Abeta aggregates and its preventionOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathomechanisms of cerebral amyloid angiopathy-related inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cerebral amyloid angiopathy-related microbleeds and CSF biomarkers in Alzheimer’s disease2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantification of molecular interactions between apoE, amyloid-beta (Aβ) and laminin: relevance to accumulation of Aβ in Alzheimer’s disease2016

Author(s)

Journal Title

Publisher

DOI

Year and Date

Language

Data Source

[Journal Article] Significant association of cadaveric dura mater grafting with subpial Aβ deposition and meningeal amyloid angiopathy2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aβ immunotherapy for Alzheimer's disease: effects on apoE and cerebral vasculopathy2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Iatrogenic Creutzfeldt-Jakob disease related to dura mater grafts2017

Author(s)

Organizer

Data Source

[Presentation] Possible human-to-human transmission of cerebral β-amyloidosis via cadaveric dura mater grafting2017

Author(s)

Organizer

Data Source

[Presentation] Aquaporin 4 and the response to Aβ immunotherapy in human Alzheimer’s disease2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Aβ immunothreapy for Alzheimer’s disease: effects on apolipoprotein E and cerebral vasculature2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Aβ immunotherapy for Alzheimer’s disease: effects on apoE and cerebral vasculopathy

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Sakai Kenji 坂井健二