SAKAI Kenji 坂井健二

… Alternative Names

Researcher Number	00572306
Other IDs
Affiliation (Current)	2018 : 金沢大学, 附属病院, 助教
Affiliation (based on the past Project Information) *help	2019 : 金沢大学, 大学病院, 助教 2016 – 2018 : 金沢大学, 附属病院, 助教 2014 – 2015 : 金沢大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Human pathology / Basic Section 52020:Neurology-related Except Principal Investigator Neurology
Keywords	Principal Investigator 脳アミロイドアンギオパチー / 遺伝子多型 / 炎症 Except Principal Investigator アミロイドβ蛋白 / アルツハイマー病 / 伝播 / 脳アミロイドアンギオパチー / 剖検脳 / アミロイドβタンパク / 凝集 / 防御

脳アミロイドアンギオパチー関連炎症動物モデルの作成と病態解析Principal InvestigatorOngoing
- Principal Investigator
  
  坂井健二
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kanazawa University
Study on transmission of Abeta aggregates and its preventionOngoing
- Principal Investigator
  
  YAMADA Masahito
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Study on transmission of sporadic cerebral amyloid angiopathy
- Principal Investigator
  
  YAMADA Masahito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Pathomechanisms of cerebral amyloid angiopathy-related inflammationPrincipal Investigator
- Principal Investigator
  
  Sakai Kenji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kanazawa University

All 2017 2016 2015 2014 Other

All Journal Article Presentation Book

[Book] 別冊「医学のあゆみ」アミロイドーシスの最新情報2017
- Author(s)
  坂井健二、山田正仁
- Total Pages
  160
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-15K15336
[Book] 最新アミロイドーシスのすべて2017
- Author(s)
  坂井健二、山田正仁、玉岡　晃
- Total Pages
  264
- Publisher
  医歯薬出版
- ISBN
  9784263731758
- Data Source
  KAKENHI-PROJECT-15K15336
[Journal Article] Coexistence of transthyretin- and Aβ-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis2017
- Author(s)
  Sakai K, Asakawa M, Takahashi R, Ishida C, Nakamura R, Hamaguchi T, Ono K, Iwasa K, Yamada M
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume : 381 Pages : 144-146
- Publisher
  Elsevier B.V.
- DOI
  10.1016/j.jns.2017.08.3240
- ISSN
  0022-510x
- Year and Date
  2017-10-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15336
[Journal Article] 脳アミロイドアンギオパチー2017
- Author(s)
  坂井健二、山田正仁
- Journal Title
  
  日本医師会雑誌
  
  Volume : 146（特別号(1)）
- Data Source
  KAKENHI-PROJECT-15K15336
[Journal Article] Cerebral amyloid angiopathy-related microbleeds and CSF biomarkers in Alzheimer’s disease2017
- Author(s)
  Noguchi-Shinohara M, Komatsu J, Samuraki M, Matsunari I, Ikeda T, Sakai K, Hamaguchi T, Ono K, Nakamura H, Yamada M.
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume : 55 Pages : 905-913
- DOI
  10.3233/jad-160651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-26860234, KAKENHI-PROJECT-15K15336
[Journal Article] Quantification of molecular interactions between apoE, amyloid-beta (Aβ) and laminin: relevance to accumulation of Aβ in Alzheimer’s disease2016
- Author(s)
  Zekonyte J, Sakai K, Nicoll JAR, Weller RO, Carare RO
- Journal Title
  
  Biochim Biophys Acta
  
  Volume : 1862 Issue : 5 Pages : 1047-1053
- Publisher
  Elsevier
- DOI
  10.1016/j.bbadis.2015.08.025
- ISSN
  0925-4439
- Year and Date
  2016-05-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860234
[Journal Article] Significant association of cadaveric dura mater grafting with subpial Aβ deposition and meningeal amyloid angiopathy2016
- Author(s)
  Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H, Yamada M.
- Journal Title
  
  Acta Neuropathol
  
  Volume : 132(2) Pages : 313-5
- DOI
  10.1007/s00401-016-1588-3
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25257506, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-26430060, KAKENHI-PROJECT-26860234, KAKENHI-PROJECT-15K08369, KAKENHI-PROJECT-16H06277
[Journal Article] Aβ immunotherapy for Alzheimer's disease: effects on apoE and cerebral vasculopathy2014
- Author(s)
  Kenji Sakai, Delphine Boche, Roxana Carare, David Johnston, Clive Holmes, Seth Love, James AR Nicoll
- Journal Title
  
  Acta Neuropathologica
  
  Volume : 128 Pages : 777-789
- DOI
  10.1007/s00401-014-1340-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860234
[Presentation] Possible human-to-human transmission of cerebral β-amyloidosis via cadaveric dura mater grafting2017
- Author(s)
  Yamada M, Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H
- Organizer
  Alzheimer's Association International Conference (AAIC) 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04194
[Presentation] Iatrogenic Creutzfeldt-Jakob disease related to dura mater grafts2017
- Author(s)
  Yamada M, Hamaguchi T, Sakai K, Noguchi-Shinohara M, Nozaki I, Taniguchi Y, Kobayashi A, Takeuchi A, Kitamoto T, Nakamura Y, Sanjo N, Tsukamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Mizusawa H
- Organizer
  PRION2017
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-17H04194
[Presentation] Cerebral amyloid angiopathy in Alzheimer's disease2017
- Author(s)
  Sakai K, Noguchi-Shinohara M, Yamada M
- Organizer
  第36回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15K15336
[Presentation] Aquaporin 4 and the response to Aβ immunotherapy in human Alzheimer’s disease2016
- Author(s)
  Sakai K, Boche D, Johnston D, Holmes C, Love S, Nicoll J
- Organizer
  5th International CAA Conference
- Place of Presentation
  Boston
- Year and Date
  2016-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860234
[Presentation] Aβ immunothreapy for Alzheimer’s disease: effects on apolipoprotein E and cerebral vasculature2015
- Author(s)
  Sakai K, Boche D, Carare R, Johnston D, Holmes C, Love S, Nicoll J
- Organizer
  7th World Congress of the International Society for Vascular Behavioural and Cognitive Disorders (Vas-Cog2015 Tokyo)
- Place of Presentation
  Tokyo Fashion Town, Tokyo
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860234
[Presentation] Aβ immunotherapy for Alzheimer’s disease: effects on apoE and cerebral vasculopathy
- Author(s)
  Kenji Sakai, Delphine Boche, Roxana Carare, David Johnston, Clive Holmes, Seth Love, James Nicoll
- Organizer
  第55回日本神経学会総会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26860234

1. YAMADA Masahito (80191336)

# of Collaborated Projects : 2results

# of Collaborated Products : 8results
2. 濱口毅 (70452109)

# of Collaborated Projects : 2results

# of Collaborated Products : 4results
3. ONO Kenjiro (70377381)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
4. 池田篤平 (30755773)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. 中山隆宏 (00532821)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. 北本哲之

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
7. 内木宏延

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
8. 高尾昌樹

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
9. 岩崎靖

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
10. 鈴木貞夫

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
11. 喜多義邦

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. 村山繁雄

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. 清水厚志

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
14. 高橋隆

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
15. 鈴木康司

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

SAKAI Kenji 坂井 健二

Sakai Kenji 坂井 健二

Research Projects

Research Products

Co-Researchers

脳アミロイドアンギオパチー関連炎症動物モデルの作成と病態解析Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on transmission of Abeta aggregates and its preventionOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on transmission of sporadic cerebral amyloid angiopathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathomechanisms of cerebral amyloid angiopathy-related inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 別冊「医学のあゆみ」 アミロイドーシスの最新情報2017

Author(s)

Total Pages

Publisher

Data Source

[Book] 最新アミロイドーシスのすべて2017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Coexistence of transthyretin- and Aβ-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis2017

Author(s)

Journal Title

Publisher

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] 脳アミロイドアンギオパチー2017

Author(s)

Journal Title

Data Source

[Journal Article] Cerebral amyloid angiopathy-related microbleeds and CSF biomarkers in Alzheimer’s disease2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantification of molecular interactions between apoE, amyloid-beta (Aβ) and laminin: relevance to accumulation of Aβ in Alzheimer’s disease2016

Author(s)

Journal Title

Publisher

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Significant association of cadaveric dura mater grafting with subpial Aβ deposition and meningeal amyloid angiopathy2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aβ immunotherapy for Alzheimer's disease: effects on apoE and cerebral vasculopathy2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Possible human-to-human transmission of cerebral β-amyloidosis via cadaveric dura mater grafting2017

Author(s)

Organizer

SAKAI Kenji 坂井健二

Sakai Kenji 坂井健二

[Book] 別冊「医学のあゆみ」アミロイドーシスの最新情報2017