ono kenjiro 小野賢二郎

… Alternative Names

Researcher Number	70377381
Other IDs
External Links
Affiliation (Current)	2022: 昭和大学, 医学部, 客員教授 2022: 金沢大学, 医学系, 教授
Affiliation (based on the past Project Information) *help	2022: 金沢大学, 医学系, 教授 2019 – 2020: 昭和大学, 医学部, 教授 2015 – 2017: 昭和大学, 医学部, 教授 2016: 金沢大学, 附属病院, 講師 2014: 金沢大学, 大学病院, 講師 … More
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Neurology / Basic Section 59040:Nutrition science and health science-related / Basic Section 59010:Rehabilitation science-related
Keywords	Principal Investigator アミロイドβ蛋白 / オリゴマー / アルツハイマー病 / レビー小体病 / α-シヌクレイン / チオフラビンS / 電子顕微鏡 / 原子間力顕微鏡 / 脳神経疾患 / 認知症 / 高速原子間力顕微鏡 / アルツハイマー病 / 毒性 … More Except Principal Investigator … More

高速原子間力顕微鏡を用いた凝集タンパクのクロス・シーディング効果の時空間的観察Principal Investigator
- Principal Investigator
  
  小野賢二郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kanazawa University
Development and evaluation of a dementia prevention support program which is provided by the collaboration of community medicine welfare, utilizing the group exercise with musical therapy
- Principal Investigator
  
  小口江美子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Showa University
膜障害に焦点を当てた高分子Aβオリゴマーの毒性機序に関する検討Principal Investigator
- Principal Investigator
  
  小野賢二郎
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Showa University
アミロイドβ毒性阻害を標的としたアルツハイマー病発症予防健康食品成分の探索
- Principal Investigator
  
  辻まゆみ
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Showa University
Study on transmission of sporadic cerebral amyloid angiopathy
- Principal Investigator
  
  YAMADA Masahito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
The elucidation of Abeta aggregation mechanism using high-speed atomic force microscopyPrincipal Investigator
- Principal Investigator
  
  Ono Kenjiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
  Kanazawa University
A study on propagation of cerebral b-amyloidosis with protein contained in foods and cosmetics
- Principal Investigator
  
  Hamaguchi Tsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Study on possible transmission of Alzheimer's disease with medical procedures and food
- Principal Investigator
  
  YAMADA Masahito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Analysis of the effect of human living specimen on amyloid β-protein oligomerizationPrincipal Investigator
- Principal Investigator
  
  ONO Kenjiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
生体分子及び有機化合物のαーシヌクレイン凝集に及ぼす影響の解析Principal Investigator
- Principal Investigator
  
  小野賢二郎
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University

[Book] 脳神経疾患最新の治療2021-20232021
- Author(s)
  小野賢二郎
- Total Pages
  380
- Publisher
  南江堂
- ISBN
  9784524227853
- Data Source
  KAKENHI-PROJECT-19K07965
[Book] Annual Review 神経20212021
- Author(s)
  小野賢二郎
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19K07965
[Book] 今日の治療指針 2021年版［デスク判］2021
- Author(s)
  小野賢二郎
- Total Pages
  2000
- Publisher
  医学書院
- ISBN
  4260042823
- Data Source
  KAKENHI-PROJECT-19K07965
[Book] 今日の診断指針デスク判第8版2020
- Author(s)
  小野賢二郎
- Total Pages
  2114
- Publisher
  医学書院
- ISBN
  9784260038089
- Data Source
  KAKENHI-PROJECT-19K07965
[Book] レビー小体型認知症診療ハンドブック2019
- Author(s)
  久保田怜美、金野竜太、黒田岳志、稗田宗太郎、矢野怜、森友紀子、二村明徳、兼元みずき、杉本あずさ、小野賢二郎
- Total Pages
  100
- Publisher
  フジメディカル出版
- ISBN
  9784862701756
- Data Source
  KAKENHI-PROJECT-19K07965
[Book] 実践高次脳機能障害のみかた2019
- Author(s)
  二村明徳、小野賢二郎
- Total Pages
  264
- Publisher
  中外医学社
- ISBN
  9784498328440
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Aβ免疫療法時代における高齢者タウオパチーの重要性2021
- Author(s)
  稗田宗太郎、小野賢二郎
- Journal Title
  
  認知症の最新医療
  
  Volume: 11 Pages: 38-40
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] 認知症診療の現状と将来展望：Aβを中心とするアプローチ2021
- Author(s)
  小野賢二郎
- Journal Title
  
  神経治療学
  
  Volume: 38
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] 認知症診療の知　アルツハイマー病の疾患修飾療法の展望2021
- Author(s)
  小野賢二郎
- Journal Title
  
  脳神経外科ジャーナル
  
  Volume: -
- NAID
  130008134331
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Mini Review: Correlations of Cognitive Domains With Cerebrospinal Fluid α-Synuclein Levels in Patients With Parkinson's Disease2021
- Author(s)
  Murakami Hidetomo、Ono Kenjiro、Shiraishi Tomotaka、Umehara Tadashi、Omoto Shusaku、Iguchi Yasuyuki
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 12 Pages: 616357-616357
- DOI
  10.3389/fnagi.2020.616357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Stopwatch training improves cognitive functions in patients with Parkinson's disease2021
- Author(s)
  Honma M, Murakami H, Yabe Y, Kuroda T, Futamura A, Sugimoto A, Terao Y, Masaoka Y, Izumizaki M, Kawamura M, Ono K.
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 99 Pages: 1325-1336
- DOI
  10.1002/jnr.24812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K03185, KAKENHI-PROJECT-19K07965
[Journal Article] 神経変性疾患の動物モデルの実験的治療：腸内微生物叢由来フェノール化合物のα-シヌクレイン凝集抑制効果2021
- Author(s)
  小野賢二郎
- Journal Title
  
  神経治療学
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Cerebrospinal fluid cytokines and metalloproteinases in cerebral amyloid angiopathy‐related inflammation2021
- Author(s)
  Sakai K, Noguchi-Shinohara M, Ikeda T, Hamaguchi T, Ono K, Yamada M
- Journal Title
  
  Acta Neurologica Scandinavica
  
  Volume: 143 Pages: 450-457
- DOI
  10.1111/ane.13382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-19K22593, KAKENHI-PROJECT-17H04194
[Journal Article] Cingulate Island Sign in Single Photon Emission Computed Tomography: Clinical Biomarker Correlations in Lewy Body Disease and Alzheimer’s Disease2021
- Author(s)
  Futamura Akinori、Hieda Sotaro、Mori Yukiko、Sugimoto Azusa、Kasai Hideyo、Kuroda Takeshi、Yano Satoshi、Kasuga Kensaku、Murakami Hidetomo、Ikeuchi Takeshi、Ono Kenjiro
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 79 Pages: 1003-1008
- DOI
  10.3233/jad-201145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-20K19111
[Journal Article] Toxic Amyloid-β42 Conformer May Accelerate the Onset of Alzheimer's Disease in the Preclinical Stage.2021
- Author(s)
  Futamura Akinori、Hieda Sotaro、Mori Yukiko、Kasuga Kensaku、Sugimoto Azusa、Kasai Hideyo、Kuroda Takeshi、Yano Satoshi、Tsuji Mayumi、Ikeuchi Takeshi、Irie Kazuhiro、Ono Kenjiro
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 80 Pages: 639-646
- DOI
  10.3233/jad-201407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-20K11266, KAKENHI-PROJECT-20K19111, KAKENHI-PROJECT-19H00921
[Journal Article] Aβ凝集制御薬2021
- Author(s)
  杉本あずさ、小野賢二郎
- Journal Title
  
  認知症の最新医療
  
  Volume: 11 Pages: 18-23
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] 言語機能障害2020
- Author(s)
  金野竜太、小野賢二郎
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 38 Pages: 211-213
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] 認知症領域におけるプロテイノパチーの病因解明up to date2020
- Author(s)
  小野賢二郎
- Journal Title
  
  老年精神医学雑誌
  
  Volume: 31 Pages: 39-45
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] 診断バイオマーカーとしてのαシヌクレイン2020
- Author(s)
  小野賢二郎
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 72 Pages: 137-141
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Increased presence of cerebral microbleeds correlates with ventricular enlargement and increased white matter hyperintensities in Alzheimer’s disease2020
- Author(s)
  Kuroda Takeshi、Honma Motoyasu、Mori Yukiko、Futamura Akinori、Sugimoto Azusa、Yano Satoshi、Kinno Ryuta、Murakami Hidetomo、Ono Kenjiro
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 12 Pages: 13-13
- DOI
  10.3389/fnagi.2020.00013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01978, KAKENHI-PROJECT-18K03185, KAKENHI-PROJECT-19K07965
[Journal Article] High-Speed Atomic Force Microscopy Reveals the Structural Dynamics of the Amyloid-β and Amylin Aggregation Pathways2020
- Author(s)
  Watanabe-Nakayama Takahiro、Sahoo Bikash R.、Ramamoorthy Ayyalusamy、Ono Kenjiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Pages: 4287-4287
- DOI
  10.3390/ijms21124287
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Gut Microbiome-Modified Polyphenolic Compounds Inhibit α-Synuclein Seeding and Spreading in α-Synucleinopathies2020
- Author(s)
  Yamasaki Tritia R.、Ono Kenjiro、Ho Lap、Pasinetti Giulio M.
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 14 Pages: 398-398
- DOI
  10.3389/fnins.2020.00398
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] 健忘2020
- Author(s)
  黒田岳志、小野賢二郎
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 38 Pages: 1391-1393
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer's disease progression.2020
- Author(s)
  Noguchi-Shinohara Moeko、Ono Kenjiro、Hamaguchi Tsuyoshi、Nagai Toshitada、Kobayashi Shoko、Komatsu Junji、Samuraki-Yokohama Miharu、Iwasa Kazuo、Yokoyama Kunihiko、Nakamura Hiroyuki、Yamada Masahito
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 18627-18627
- DOI
  10.1038/s41598-020-73729-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09795, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-20K20309, KAKENHI-PROJECT-19K22751, KAKENHI-PROJECT-17H04194, KAKENHI-PROJECT-19H03882
[Journal Article] Novel VPS13A Gene Mutations in a South Asian, Indian Patient with Chorea?acanthocytosis2020
- Author(s)
  Futamura A, Nakamura M, Kawamura M Sano A, Ono K
- Journal Title
  
  Neurology India
  
  Volume: 68 Pages: 206-208
- DOI
  10.4103/0028-3886.279653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07606, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-17H04250
[Journal Article] Spontaneous MEG activity of the cerebral cortex during eyes closed and open discriminates Alzheimer's disease from cognitively normal older adults.2020
- Author(s)
  Ikeda Yoshihisa、Kikuchi Mitsuru、Noguchi-Shinohara Moeko、Iwasa Kazuo、Kameya Masafumi、Hirosawa Tetsu、Yoshita Mitsuhiro、Ono Kenjiro、Samuraki-Yokohama Miharu、Yamada Masahito
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 9132-9132
- DOI
  10.1038/s41598-020-66034-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09795, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-17H04194
[Journal Article] Anti-aggregation Effects of Phenolic Compounds on α-synuclein2020
- Author(s)
  Ono Kenjiro、Tsuji Mayumi、Yamasaki Tritia R.、Pasinetti Giulio M.
- Journal Title
  
  Molecules
  
  Volume: 25 Pages: 2444-2444
- DOI
  10.3390/molecules25102444
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Pallidal dementia with underlying sleep apnea syndrome: a case report and literature review2020
- Author(s)
  Sugimoto A, Shozawa H, Mizuma K, Hieda S, Ono K
- Journal Title
  
  Neurol Sci
  
  Volume: -
- DOI
  10.1007/s10072-020-04273-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Discriminating chorea-acanthocytosis from Huntington's disease with single-case voxel-based morphometry analysis2020
- Author(s)
  Suzuki F, Sato N, Ota M, Sugiyama A, Shigeyamay, Morimoto E, Kimura Y, Wakasugi N, Takahashi Y, Futamura A, Kawamura M, Ono K, Nakamura M, Sano A, Watanabe Masako, Mathuda H, Abe O
- Journal Title
  
  J Neurol Sci.
  
  Volume: 408 Pages: 116545-116545
- DOI
  10.1016/j.jns.2019.116545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07606, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-17H04250, KAKENHI-PROJECT-17K10424
[Journal Article] Protofibrils of Amyloid-β are Important Targets of a Disease-Modifying Approach for Alzheimer’s Disease2020
- Author(s)
  Ono Kenjiro、Tsuji Mayumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Pages: 952-952
- DOI
  10.3390/ijms21030952
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Self- and Cross-Seeding on α-Synuclein Fibril Growth Kinetics and Structure Observed by High-Speed Atomic Force Microscopy2020
- Author(s)
  Takahiro Watanabe-Nakayama, Maika Nawa, Hiroki Konno, Noriyuki Kodera, Toshio Ando, David B Teplow, Kenjiro Ono
- Journal Title
  
  ACS Nano
  
  Volume: 14 Pages: 9979-9989
- DOI
  10.1021/acsnano.0c03074
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06596, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-20H00327
[Journal Article] Nonsystemic vasculitic neuropathy in a patient with IgG-monoclonal gammopathy of undetermined significance2020
- Author(s)
  Kinno Ryuta、Osakabe Yuyuko、Takahashi Seiya、Kurokawa Shinji、Owan Yoshiyuki、Ono Kenjiro、Baba Yasuhiko
- Journal Title
  
  Medicine
  
  Volume: 99
- DOI
  10.1097/md.0000000000019036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01978, KAKENHI-PROJECT-19K07965
[Journal Article] Three-dimensional Imaging of Abducens Palsy by Neurovascular Compression2020
- Author(s)
  Sugimoto Azusa、Kuroda Takeshi、Tsuda Hiromasa、Ono Kenjiro
- Journal Title
  
  Internal Medicine
  
  Volume: 59 Issue: 2 Pages: 305-307
- DOI
  10.2169/internalmedicine.3445-19
- NAID
  130007785092
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Pine Bark Polyphenolic Extract Attenuates Amyloid-β and Tau Misfolding in a Model System of Alzheimer’s Disease Neuropathology2020
- Author(s)
  Ono Kenjiro、Zhao Daisy、Wu Qingli、Simon James、Wang Jun、Radu Aurelian、Pasinetti Giulio Maria
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 73 Pages: 1597-1606
- DOI
  10.3233/jad-190543
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] A new computerized assessment battery for cognition (C-ABC) to detect mild cognitive impairment and dementia around 5 min2020
- Author(s)
  Noguchi-Shinohara Moeko、Domoto Chiaki、Yoshida Taketoshi、Niwa Kozue、Yuki-Nozaki Sohshi、Samuraki-Yokohama Miharu、Sakai Kenji、Hamaguchi Tsuyoshi、Ono Kenjiro、Iwasa Kazuo、Matsunari Ichiro、Komai Kiyonobu、Nakamura Hiroyuki、Yamada Masahito
- Journal Title
  
  PLOS ONE
  
  Volume: 15
- DOI
  10.1371/journal.pone.0243469
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09795, KAKENHI-PROJECT-19K07965
[Journal Article] A New Serum Biomarker Set to Detect Mild Cognitive Impairment and Alzheimer’s Disease by Peptidome Technology2020
- Author(s)
  Abe K, Shang J, Shi X, Yamashita T, Hishikawa N, Takemoto M, Morihara R, Nakano Y, Ohta Y, Deguchi K, Ikeda M, Ikeda Y, Okamoto K, Shoji M, Takatama M, Kojo M, Kuroda T, Ono K, Kimura N, Matsubara E, Osakada Y, Wakutani Y, Takao Y, Higashi Y, Asada K, Senga T, Lee LJ, Tanaka K
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 73(1) Pages: 217-227
- DOI
  10.3233/jad-191016
- NAID
  120006949464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-18K07491, KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-17H04196, KAKENHI-PROJECT-19H03566
[Journal Article] The relationship between thyroid function and cerebral blood flow in mild cognitive impairment and Alzheimer’s disease2019
- Author(s)
  Nomoto Shohei、Kinno Ryuta、Ochiai Hirotaka、Kubota Satomi、Mori Yukiko、Futamura Akinori、Sugimoto Azusa、Kuroda Takeshi、Yano Satoshi、Murakami Hidetomo、Shirasawa Takako、Yoshimoto Takahiko、Minoura Akira、Kokaze Akatsuki、Ono Kenjiro
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Pages: 0214676-0214676
- DOI
  10.1371/journal.pone.0214676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01978, KAKENHI-PROJECT-19K07965
[Journal Article] Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid beta aggregation by increasing monoamine secretion.2019
- Author(s)
  Hase Tomoki、Shishido Syun、Yamamoto So、Yamashita Rei、Nukima Haruka、Taira Shu、Toyoda Tsudoi、Abe Keiko、Hamaguchi Tsuyoshi、Ono Kenjiro、Noguchi-Shinohara Moeko、Yamada Masahito、Kobayashi Shoko
- Journal Title
  
  Sci. Rep.
  
  Volume: 9 Pages: 8711-8711
- DOI
  10.1038/s41598-019-45168-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09795, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-17H01962, KAKENHI-PROJECT-18K19728
[Journal Article] 上位頸髄梗塞をきたした69歳男性例2019
- Author(s)
  栗城綾子、神谷雄己、宮内淑史、水間啓太、小室浩康、福田早織、藤井隆史、河面有倫、新井晋太郎、池田尚人、小野賢二郎
- Journal Title
  
  Journal of Japan Society of Neurological Emergencies & Critical Care
  
  Volume: 31 Pages: 63-68
- NAID
  130007695312
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] 抗アミロイドβ系薬剤2019
- Author(s)
  杉本あずさ、小野賢二郎
- Journal Title
  
  老年精神医学雑誌
  
  Volume: 30 Pages: 653-662
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] High molecular weight amyloid β 1‐42 oligomers induce neurotoxicity via plasma membrane damage2019
- Author(s)
  Yasumoto Taro、Takamura Yusaku、Tsuji Mayumi、Watanabe‐Nakayama Takahiro、Imamura Keiko、Inoue Haruhisa、Nakamura Shiro、Inoue Tomio、Kimura Atsushi、Yano Satoshi、Nishijo Hisao、Kiuchi Yuji、Teplow David B.、Ono Kenjiro
- Journal Title
  
  FASEB J.
  
  Volume: 33 Pages: 9220-9234
- DOI
  10.1096/fj.201900604r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-19K10048, KAKENHI-PROJECT-19K11698, KAKENHI-PROJECT-19K22726, KAKENHI-PROJECT-17H04373, KAKENHI-PROJECT-16K11488, KAKENHI-PROJECT-17K10297
[Journal Article] Aβ凝集制御薬2019
- Author(s)
  杉本あずさ、小野賢二郎
- Journal Title
  
  認知症の最新医療
  
  Volume: 9 Pages: 138-142
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Pharmacological Potential of Cilostazol for Alzheimer’s Disease2019
- Author(s)
  Ono Kenjiro、Tsuji Mayumi
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 10 Pages: 559-559
- DOI
  10.3389/fphar.2019.00559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Correlated levels of cerebrospinal fluid pathogenic proteins in drug-na?ve Parkinson’s disease2019
- Author(s)
  Murakami Hidetomo、Tokuda Takahiko、El-Agnaf Omar M. A.、Ohmichi Takuma、Miki Ayako、Ohashi Hideaki、Owan Yoshiyuki、Saito Yu、Yano Satoshi、Tsukie Tamao、Ikeuchi Takeshi、Ono Kenjiro
- Journal Title
  
  BMC Neurology
  
  Volume: 19 Pages: 113-113
- DOI
  10.1186/s12883-019-1346-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Contraction of distance and duration production in autism spectrum disorder2019
- Author(s)
  Honma, M., Itoi, C., Midorikawa, A., Terao, Y., Masaoka, Y., Kuroda, T., Futamura, A., Shiromaru, A., Kawamura, M., Ono, K.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 8806-8806
- DOI
  10.1038/s41598-019-45250-8
- NAID
  130008126764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K03185, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-18H03663, KAKENHI-PLANNED-18H05523
[Journal Article] アルツハイマー病におけるbrain lymphatic drainage systemの障害2019
- Author(s)
  黒田岳志、小野賢二郎
- Journal Title
  
  認知症の最新医療
  
  Volume: 9 Pages: 212-213
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Mechanisms of Immune Activation by c9orf72-Expansions in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia2019
- Author(s)
  Trageser Kyle J.、Smith Chad、Herman Francis J.、Ono Kenjiro、Pasinetti Giulio Maria
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 13 Pages: 1298-1298
- DOI
  10.3389/fnins.2019.01298
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] 本邦における新規MAO-B阻害薬ラサギリンの長期使用経験<第1報>2019
- Author(s)
  馬場康彦、高橋聖也、小野賢二郎
- Journal Title
  
  Geriatric Medicine
  
  Volume: 57 Pages: 983-987
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Granuloma formation in a patient with GNE myopathy: A case report.2017
- Author(s)
  Nakamura K, Hamaguchi T, Sakai K, Noto D, Ono K, Hayashi Y, Nishino I, Yamada M.
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 27 Pages: 183-184
- DOI
  10.1016/j.nmd.2016.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Cerebral amyloid angiopathy-related microbleeds and CSF biomarkers in Alzheimer’s disease2017
- Author(s)
  Noguchi-Shinohara M, Komatsu J, Samuraki M, Matsunari I, Ikeda T, Sakai K, Hamaguchi T, Ono K, Nakamura H, Yamada M.
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 55 Pages: 905-913
- DOI
  10.3233/jad-160651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-26860234, KAKENHI-PROJECT-15K15336
[Journal Article] Tocotrienol-Rich Fraction Modulates Amyloid Pathology and Improves Cognitive Function in AβPP/PS1 Mice.2017
- Author(s)
  Ibrahim NF, Yanagisawa D, Durania LW, Hamezaha HS, HDamanhuri HD, Wan Ngahb WZ, Tsuji M, Kiuchi Y, Ono K, Tooyama I
- Journal Title
  
  Journal of Alzheimer’s Disease
  
  Volume: 55 Pages: 51-61
- DOI
  10.3233/jad-160685
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290022, KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-15K16321
[Journal Article] MELAS: Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes2017
- Author(s)
  村上秀友, 小野賢二郎
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 69 Issue: 2 Pages: 111-117
- DOI
  10.11477/mf.1416200650
- ISSN
  1344-8129, 1881-6096
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Coexistence of transthyretin- and Aβ-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis2017
- Author(s)
  Sakai K, Asakawa M, Takahashi R, Ishida C, Nakamura R, Hamaguchi T, Ono K, Iwasa K, Yamada M
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 381 Pages: 144-146
- DOI
  10.1016/j.jns.2017.08.3240
- NAID
  120006375106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15336
[Journal Article] α-シヌクレイン凝集とレビー小体型認知症の根本治療薬開発2016
- Author(s)
  高橋良一, 小野賢二郎, 山田正仁
- Journal Title
  
  認知症の最新医療
  
  Volume: 6 Pages: 128-133
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] 抗パーキンソン病薬・抗てんかん薬によって誘発される認知症・認知障害2016
- Author(s)
  村上秀友, 小野賢二郎
- Journal Title
  
  医薬ジャーナル
  
  Volume: 52 Pages: 2489-2491
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] High-speed atomic force microscopy reveals structural dynamics of amyloid β1-42 aggregates.2016
- Author(s)
  Watanabe-Nakayama T*, Ono K*, Itami M, Takahashi R, Teplow DB, Yamada M. *Equally contributed.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 113 Pages: 5835-5840
- DOI
  10.1073/pnas.1524807113
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] パーキンソン病の認知障害のバイオマーカー2016
- Author(s)
  小野賢二郎, 山田正仁
- Journal Title
  
  Dementia Japan
  
  Volume: 30 Pages: 223-228
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers.2016
- Author(s)
  Umeda T., Ono K., Sakai A., Yamashita M., Mizuguchi M, Klein W.L., Yamada M., Mori H., Tomiyama T
- Journal Title
  
  Brain
  
  Volume: 139 Pages: 1568-1586
- DOI
  10.1093/brain/aww042
- NAID
  120006371274
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290018, KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-16K19057
[Journal Article] 高齢者てんかんと認知症の関連2016
- Author(s)
  石垣征一郎, 小野賢二郎
- Journal Title
  
  認知症の最新医療
  
  Volume: 6 Pages: 189-190
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Improvement in Language Function Correlates with Gait Improvement in Drug-naïve Parkinson's Disease Patients Taking Dopaminergic Medication2016
- Author(s)
  Murakami H., Momma Y., Nohara T., Mori Y., Futamura A., Sugita T., Ishigaki S., Katoh H., Kezuka M., Ono K., Miller M.W., Kawamura M.
- Journal Title
  
  J Parkinsons Dis.
  
  Volume: 6 Pages: 209-217
- DOI
  10.3233/jpd-150702
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461266, KAKENHI-PLANNED-25119006
[Journal Article] Aβ凝集に焦点をあてたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎, 山田正仁
- Journal Title
  
  老年期認知症研究会誌
  
  Volume: 21 Pages: 20-22
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] fMRIからみた統辞処理の神経機構2016
- Author(s)
  金野竜太, 小野賢二郎
- Journal Title
  
  高次脳機能研究
  
  Volume: 36 Pages: 255-262
- NAID
  130006894317
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] アルツハイマー型認知症および認知症の疫学研究2016
- Author(s)
  石垣征一郎, 小野賢二郎
- Journal Title
  
  Pharma Medica
  
  Volume: 34 Pages: 9-12
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] オリゴマー仮説に基づいたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Journal Title
  
  神経化学
  
  Volume: 55 Pages: 42-51
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Efficacy of levetiracetam in primary hemifacial spasm.2016
- Author(s)
  Kuroda T, Saito Y, Fujita K, Yano S, Ishigaki S, Kato H, Murakami H, Ono K.
- Journal Title
  
  J Clin Neurosci
  
  Volume: 34 Pages: 213-215
- DOI
  10.1016/j.jocn.2016.05.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Parkinson病および関連疾患の治療の進歩2016
- Author(s)
  村上秀友, 小野賢二郎, 河村満
- Journal Title
  
  神経治療薬
  
  Volume: 4 Pages: 518-521
- NAID
  130006638881
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Cerebral amyloid angiopathy-related microbleeds correlate with glucose metabolism and brain volume in Alzheimer's disease.2015
- Author(s)
  Samuraki M., Matsunari I., Yoshita M., Shima K., Noguchi-Shinohara M., Hamaguchi T., Ono K., Yamada M.
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 48 Pages: 517-528
- DOI
  10.3233/jad-150274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Pharmacokinetics, safety and tolerability of rosmarinic acid in healthy individuals2015
- Author(s)
  Noguchi-Shinohara M., Ono K., Hamaguchi T., Iwasa K., Nagai T., Kobayashi S., Nakamura H., Yamada M.
- Journal Title
  
  PLoS One.
  
  Volume: 10
- DOI
  10.1371/journal.pone.0126422
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-15H02894, KAKENHI-PROJECT-15H04783, KAKENHI-PROJECT-25670295
[Journal Article] Phenolic compounds prevent the oligomerization of α-synuclein and reduce synaptic toxicity.2015
- Author(s)
  Takahashi R., Ono K., Takamura Y., Mizuguchi M., Ikeda T., Nishijo H., Yamada M.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 134 Pages: 943-955
- DOI
  10.1111/jnc.13180
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Exacerbation of myasthenia gravis by intravenous peramivir.2015
- Author(s)
  Hayashi K., Iwasa K., Morinaga A., Ono K., Yamada M.
- Journal Title
  
  Muscle & Nerve
  
  Volume: 51 Pages: 935-936
- DOI
  10.1002/mus.24594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Role of intestinal microbiota in the generation of polyphenol derived phenolic acid mediated attenuation of Alzheimer’s disease β-amyloid oligomerization.2015
- Author(s)
  Wang D., Ho L., Faith J., Ono K., Janle E.M., Lachcik P.J., Cooper B.R., Jannasch A.H., D’Arcy B.R., Williams B.A., Ferruzzi M.G., Levine S., Zhao W., Dubner L., Pasinetti G.M.
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 59 Pages: 1025-1040
- DOI
  10.1002/mnfr.201400544
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Inclusion body myositis with granuloma formation in muscle tissue.2015
- Author(s)
  Sakai K, Ikeda Y, Ishida C, Matsumoto Y, Ono K, Iwasa K, Yamada M.
- Journal Title
  
  Neuromuscular Disorders
  
  Volume: 25 Pages: 706-712
- DOI
  10.1016/j.nmd.2015.06.460
- NAID
  120005661916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Neurolymphomatosis exhibiting repeated exacerbation and remission in both the peripheral and central nervous systems.2014
- Author(s)
  Akagi A, Ono K, Hamaguchi T, Samuraki M, Nakada M, Shima Y, Oohata T, Yamada M.
- Journal Title
  
  J Neurol Sci
  
  Volume: 345 Pages: 267-268
- DOI
  10.1016/j.jns.2014.07.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Efficacy of diflunisal on autonomic dysfunction of late-onset familial amyloid polyneuropathy (TTR Val30Met) in a Japanese endemic area2014
- Author(s)
  Takahashi R, Ono K, Shibata S, Nakamura K, Komatsu J, Ikeda Y, Ikeda T, Samuraki M, Sakai K, Iwasa K, Kayano D, Yamada M
- Journal Title
  
  J Neurol Sci
  
  Volume: 345 Pages: 231-235
- DOI
  10.1016/j.jns.2014.07.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Molecular topology as novel strategy for discovery of drugs with Aβ lowering and anti-aggregation dual activities for Alzheimer's disease2014
- Author(s)
  Wang J, Land D, Ono K, Galvez J, Zhao W, Vempati P, Steele JW, Cheng A, Yamada M, Levine S, Mazzola P, Pasinetti GM
- Journal Title
  
  PLoS One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0092750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Cocoa extracts reduce oligomerization of amyloid-β: implications for cognitive improvement in Alzheimer's disease2014
- Author(s)
  Wang J, Varghese M, Ono K, Yamada M, Levine S, Tzavaras N, Gong B, Hurst WJ, Blitzer RD, Pasinetti GM
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 41 Pages: 643-650
- DOI
  10.3233/jad-132231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Effects of the neurotrophic agent T-817MA on oligomeric amyloid β-induced deficits in long-term potentiation in the hippocampal CA1 subfield2014
- Author(s)
  Takamura Y*, Ono K*, Matsumoto J, Yamada M, Nishijo H ＊Equally contributed
- Journal Title
  
  Neurobiol Aging
  
  Volume: 35 Pages: 532-536
- DOI
  10.1016/j.neurobiolaging.2013.08.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Myasthenia gravis: predictive factors associated with the synchronized elevation of anti-acetylcholine receptor antibody titer in Kanazawa, Japan.2014
- Author(s)
  Iwasa K, Yoshikawa H, Samuraki M, Shinohara M, Hamaguchi T, Ono K, Nakamura H, Yamada M
- Journal Title
  
  J Neuroimmunol.
  
  Volume: 267(2014) Pages: 97-101
- DOI
  10.1016/j.jneuroim.2013.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390160, KAKENHI-PROJECT-24591253, KAKENHI-PROJECT-25670295, KAKENHI-PROJECT-26461266
[Journal Article] Exogenous amyloidogenic proteins function as seeds in amyloid β-protein aggregation2014
- Author(s)
  Ono K, Takahashi R, Ikeda T, Mizuguchi M, Hamaguchi T, Yamada M
- Journal Title
  
  Biochim Biophys Acta (Molecular Basis of Disease)
  
  Volume: 1842 Pages: 646-653
- DOI
  10.1016/j.bbadis.2014.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Green coffee as a novel agent for Alzheimer’s disease prevention by attenuating diabetes2014
- Author(s)
  Varghese M, Ho L, Wang J, Zhao W, Levine S, Ono K, Mannino S, Pasinetti GM
- Journal Title
  
  Translational Neuroscience
  
  Volume: 5 Pages: 111-116
- DOI
  10.2478/s13380-014-0213-y
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment2012
- Author(s)
  Wang J, Ferruzzi MG, Ho L, Blount J, Janle EM, Gong B, Pan Y, Gowda N, Raftery D, Arrieta-Cruz I, Sharma V, Cooper B, Lobo J, Simon J, Zhang C, Cheng A, Qian X, Ono K, Teplow DB, Pavlides C, Dixon R, Pasinetti G
- Journal Title
  
  J Neurosci
  
  Volume: 11 Pages: 5144-5150
- DOI
  10.1523/jneurosci.6437-11.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Vitamin A and Alzheimer’s disease2012
- Author(s)
  Ono K, Yamada M
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 12 Pages: 180-188
- DOI
  10.1111/j.1447-0594.2011.00786.x
- NAID
  10031147981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Posterior cingulate atrophy and metabolic decline in early stage Alzheimer's disease.2012
- Author(s)
  Shima K, Samuraki M, Chen WP, Yanase D, Noguchi-Shinohara M, Takeda N, Ono K, Yoshita M, Miyazaki Y, Matsuda H, Yamada M, Matsunari I
- Journal Title
  
  Neurobiol Aging
  
  Volume: 33 Pages: 2006-2017
- DOI
  10.1016/j.neurobiolaging.2011.07.009
- NAID
  10031007048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Phenolic compounds prevent amyloid β-protein oligomerization and synaptic dysfunction by site specific binding.2012
- Author(s)
  Ono K, Li L, Takamura Y, Yoshiike Y, Zhu L, Han F, Mao X, Ikeda T, Takasaki JI, Nishijo H, Takashima A, Teplow DB, Zagorski MG, Yamada M
- Journal Title
  
  J Biol Chem
  
  Volume: (印刷中) Pages: 14631-14643
- DOI
  10.1074/jbc.m111.325456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390242, KAKENHI-PROJECT-22240051, KAKENHI-PROJECT-22790815
[Journal Article] Cross-seeding effects of amyloid β-protein and α-synuclein2012
- Author(s)
  Ono K,*Takahashi R,*Ikeda T, Yamada M
- Journal Title
  
  J. Neurochem
  
  Volume: 122 Pages: 883-890
- DOI
  10.1111/j.1471-4159.2012.07847.x
- NAID
  120005285928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659170, KAKENHI-PROJECT-22790815
[Journal Article] Vitamin A and Alzheimer's disease2012
- Author(s)
  Ono. K. Yamada. M
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: (in press)
- NAID
  10031147981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Effect of melatonin on α-synuclein self-assembly and cytotoxicity2012
- Author(s)
  Ono K, Mochizuki H, Ikeda T, Nihira T, Takasaki J, Teplow DB, Yamada M
- Journal Title
  
  Neurobiol Aging
  
  Volume: 33 Pages: 2172-2185
- DOI
  10.1016/j.neurobiolaging.2011.10.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Parkinson's disease showing progressive conduction aphasia2012
- Author(s)
  Sakai K, Ono K, Harada H, Shima K, Notoya M, Yamada M
- Journal Title
  
  Neurol. Sci
  
  Volume: 33 Pages: 399-402
- DOI
  10.1007/s10072-011-0751-9
- NAID
  120003386992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Nicotinamide riboside restores cognition through an up-regulation of PGC-1α regulated BACE1 degradation and mitochondrial gene expression in Alzheimer's mouse models2012
- Author(s)
  Gong B, Pan Y, Vempati P, Zhao W, Knable L, Ho L, Wang J, Sastre M, Ono K, Pasinetti GM
- Journal Title
  
  Neurobiol. Aging
  
  Volume: (in press)
- URL
  http://dx.doi.org/10.1016/j.neurobiolaging.2012.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Coagulation and fibrinolysis abnormalities in familial amyloid polyneuropathy2012
- Author(s)
  Takahashi R, Ono K, Ikeda T, Akagi A, Noto D, Nozaki I, Sakai K, Asakura H, Iwasa K, Yamada M
- Journal Title
  
  Amyloid
  
  Volume: 19 Pages: 129-132
- DOI
  10.3109/13506129.2012.691918
- NAID
  120004754690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Anti-amyloidogenic effects of soybean isoflavones in vitro: fluorescence spectroscopy demonstrating direct binding to Aβ monomers, oligomers and fibrils.2012
- Author(s)
  Hirohata M, Ono K, Takasaki JI, Takahashi R, Ikeda T, Morinaga A, Yamada M
- Journal Title
  
  Biochim. Biophys. Acta (Molecular Basis of Disease)
  
  Volume: 1822 Pages: 1316-1324
- DOI
  10.1016/j.bbadis.2012.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment2012
- Author(s)
  Wang. J, Ferruzzi. MG, Ho. L,Blount. J, Janle. EM, Gong. B,Pan. Y, Gowda. N, Raftery. D,Arrieta-Cruz. I, Sharma. V, Cooper. B, Lobo. J, Simon. J, Zhang. C, Cheng. A, Qian. X, Ono. K, Teplow. DB, Pavlides. C, Dixon. R, Pasinetti. G
- Journal Title
  
  J Neurosci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cerebrospinal fluid from patients with multiple system atrophy promotes in vitro α-synuclein fibril formation2011
- Author(s)
  Hirohata M, Ono K, Morinaga A, Ikeda T, Yamada M
- Journal Title
  
  Neurosci. Lett
  
  Volume: 491 Pages: 48-52
- DOI
  10.1016/j.neulet.2011.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Effect of an age-mismatched and sex-mismatched normal database on the diagnostic performance of ^<18>F-FDG PET for Alzheimer's disease : the Ishikawa Brain Imaging Study2011
- Author(s)
  Chen WP, Samuraki M, Shima K, Yanase D, Nozomi, Takeda N, Miyazaki Y, Ono K, Yoshita M, Nishimura S, Yamada M, Matsunari I
- Journal Title
  
  Nucl Med Commun
  
  Volume: 32 Pages: 1128-1133
- DOI
  10.1097/mnm.0b013e32834b43c2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Findings of Familial Dementia with a Tau R406W Mutation2011
- Author(s)
  Komatsu. J, Ono. K,Yanase. D, Samuraki. M, Shima. K, Kuwano. R, Matsunari. I, Yamada. M
- Journal Title
  
  Acta Neurol Berg
  
  Volume: 111 Pages: 374-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Vitamin A has antioligomerization effects on amyloid-β in vitro2011
- Author(s)
  Takasaki J-I, Ono K, Yoshiike Y, Hirohata M, Ikeda T, Morinaga A, Takashima A, Yamada M
- Journal Title
  
  J. Alzheimers. Dis
  
  Volume: 27 Pages: 271-280
- DOI
  10.3233/jad-2011-110455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390242, KAKENHI-PROJECT-22790815
[Journal Article] Cerebrospinal fluid from patients with multiple system atrophy promotes in vitro α-synuclein fibril formation2011
- Author(s)
  Hirohata. M, Ono. K, Morinaga. A, Ikeda. T, Yamada. M
- Journal Title
  
  Neurosci Lett
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Imaging Findings of Familial Dementia with a Tau R406W Mutation2011
- Author(s)
  Komatsu J, Ono K, Yanase D, Samuraki M, Shima K, Kuwano R, Matsunari I, Yamada M
- Journal Title
  
  Acta Neurol. Berg
  
  Volume: 111 Pages: 374-375
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22368988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cervical flexion myelopathy in a patient showing apparent long tract signs: a severe form of Hirayama disease2011
- Author(s)
  Sakai K, Ono K, Okamoto Y, Murakami H and Yamada M
- Journal Title
  
  Joint Bone Spine
  
  Volume: 78 Pages: 316-318
- DOI
  10.1016/j.jbspin.2010.12.008
- NAID
  120002772028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Carvedilol as a potential novel agent for the treatment of Alzheimer's disease2011
- Author(s)
  Wang J, Ono K, Dickstein D, Arrieta-Cruz I, Zhao W, Qian X, Lamparello A, Ferruzzi MG, Pavlides C, Ho L, Hof P, Teplow DB, Pasinetti GM
- Journal Title
  
  Neurobiol. Aging
  
  Volume: 32
- DOI
  10.1016/j.neurobiolaging.2010.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Familial Parkinson disease mutations influence α-synuclein assembly2011
- Author(s)
  Ono K, Takasaki J, Ikeda T, Yamada M
- Journal Title
  
  Neurobiol Dis
  
  Volume: 43 Pages: 715-724
- DOI
  10.1016/j.nbd.2011.05.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Low-n oligomers as therapeutic targets of Alzeheimer's disease2011
- Author(s)
  Ono K, Yamada M
- Journal Title
  
  J Neurochem
  
  Volume: 117 Pages: 19-28
- DOI
  10.1111/j.1471-4159.2011.07187.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cervical flexion myelopathy in a patient showing apparent long tract signs : a severe form of Hirayama disease2011
- Author(s)
  Sakai. K, Ono. K,Okamoto. Y, Murakami. H, Yamada. M
- Journal Title
  
  Joint Bone Spine
  
  Volume: 78 Pages: 316-318
- NAID
  120002772028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Fisher syndrome associated with immune thrombocytopenic purpura2011
- Author(s)
  Furukawa Y, Iwasa K, Ono K and Yamada M
- Journal Title
  
  Intern. Med
  
  Volume: 50 Pages: 631-633
- NAID
  130000649898
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21422692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Effects of sex hormones on Alzheimer's disease-associated β-amyloid oligomer formation in vitro2011
- Author(s)
  Morinaga A, Ono K, Takasaki J, Ikeda T, Hirohata M, Yamada M
- Journal Title
  
  Exp Neurol
  
  Volume: 228 Pages: 298-302
- DOI
  10.1016/j.expneurol.2011.01.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease2010
- Author(s)
  Wang J, Santa-Maria I, Ho L, Ksiezak-Reding H, Ono K, Teplow DB, Pasinetti GM
- Journal Title
  
  J. Alzheimers. Dis
  
  Volume: 22 Pages: 653-661
- DOI
  10.3233/jad-2010-101074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] A comparison of the diagnostic sensitivity of MRI, CBF-SPECT, FDG-PET, and cerebrospinal fluid biomarkers for detecting Alzheimer's disease in a memory clinic2010
- Author(s)
  Morinaga. A, Ono. K, Ikeda. T, Ikeda. Y, Shima. K, Shinohara. M, Samuraki. M, Yanase. D, Yoshita. M, Mastunari. I, Yamada. M
- Journal Title
  
  Dement Geriatr Cogn Disord
  
  Volume: 30 Pages: 285-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cerebrospinal fluid of Alzheimer patients promotes amyloid β-Protein oligomerization2010
- Author(s)
  Ikeda. T, Ono. K, Elashoff. D, Condron. MM, Noguchi-Shinohara. M, Yoshita. M, Teplow. DB, Yamada. M
- Journal Title
  
  J Alzheimcrs Dis
  
  Volume: 21 Pages: 81-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Curcumin and Alzheimer's disease2010
- Author(s)
  Hamaguchi. T, Ono. K, Yamada. M
- Journal Title
  
  CNS Neurosci Ther
  
  Volume: 16 Pages: 285-297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease2010
- Author(s)
  Wang. J, Santa-Maria. I, Ho. L, Ksiezak-Reding. H, Ono. K, Teplow. DB, Pasinetti. GM
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 22 Pages: 653-661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cerebrospinal fluid of Alzheimer patients promotes amyloid β-Protein oligomerization2010
- Author(s)
  Ikeda T, Ono K, Elashoff D, Margaret C, Noguchi-Shinohara M, Yoshita M, Teplow DB, Yamada M
- Journal Title
  
  J. Alzheimers. Dis
  
  Volume: 21 Pages: 81-86
- DOI
  10.3233/jad-2010-100075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Ono K, Condron MM, Teplow DB2010
- Author(s)
  Ono K, Condron MM, Teplow DB
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 23186-23197
- DOI
  10.1074/jbc.m109.086496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Sakai K, Ono K, Ohta K, Yamada M2010
- Author(s)
  Sakai K, Ono K, Ohta K, Yamada M
- Journal Title
  
  Intern. Med
  
  Volume: 49 Pages: 1261-1262
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20558962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Effects of the English (H6R) and Tottori (D7N) familial Alzheimer disease mutations on amyloid β-protein assembly and toxicity2010
- Author(s)
  Ono. K, Condron. MM, Teplow. DB
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 23186-23197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Curcumin and Alzheimer's disease2010
- Author(s)
  Hamaguchi T, Ono K, Yamada M.
- Journal Title
  
  CNS Neurosci. Ther
  
  Volume: 16 Pages: 285-297
- DOI
  10.1111/j.1755-5949.2010.00147.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] A comparison of the diagnosticsensitivity of MRI, CBF-SPECT, FDG-PET, and cerebrospinal fluid biomarkers for detecting Alzheimer's disease in a memory clinic2010
- Author(s)
  Morinaga A, Ono K, Ikeda T, Ikeda Y, Shima K, Shinohara M,Samuraki M,Yanase D, Yoshita M, Mastunari I, Yamada M
- Journal Title
  
  Dement. Geriatr. Cogn. Disord
  
  Volume: 30 Pages: 285-292
- DOI
  10.1159/000320265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Vitamin A potently destabilizes preformed alpha-synuclein fibrils in vitro : Implications for Lewy body diseases.2007
- Author(s)
  Kenjiro Ono, Masahito Yamada
- Journal Title
  
  Neurobiol Dis 25
  
  Pages: 446-454
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Cerebrospinal fluid of Alzheimer's disease and dementia with Lewy bodies patients enhances alpha-synuclein fibril formation. in vitro.2007
- Author(s)
  Kenjiro Ono, Noguchi-Shinohara M, Mitsuhiro Yoshita, Hironobu Naiki, Masahito Yamada
- Journal Title
  
  Exp Neurol 203
  
  Pages: 579-583
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro.2006
- Author(s)
  Kenjiro Ono, Masahito Yamada
- Journal Title
  
  J Neurochem 97
  
  Pages: 105-115
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Alpha-lipoic acid exhibits anti-amyloidogenicity for beta-amyloid fibrils in vitro.2006
- Author(s)
  Kenjiro Ono, Mie Hirohata, Masahito Yamada
- Journal Title
  
  Biochem Biophys Res Commun 341
  
  Pages: 1046-1052
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Anti-Parkinsonian agents have anti-amyloidogenic activity for Alzheimer's beta-amyloid fibrils in vitro.2006
- Author(s)
  Kenjiro Ono, Kazuhiro Hasegawa, Hironobu Naiki, Masahito Yamada
- Journal Title
  
  Neurochem Int 48
  
  Pages: 275-285
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Anti-fibrillogenic and fibril-destabilizing activities of anti-Parkinsonian agents for alpha-synuclein fibrils in vitro.
- Author(s)
  Kenjiro Ono, Mie Hirohata, Masahito Yamada
- Journal Title
  
  J Neurosci Res (印刷中)
- Data Source
  KAKENHI-PROJECT-18790589
[Patent] レビー小体病治療薬及びレビー小体病予防薬2006
- Inventor(s)
  山田正仁, 小野賢二郎
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Filing Date
  2006-01-16
- Data Source
  KAKENHI-PROJECT-18790589
[Presentation] MYRICETIN PREVENTS HIGH MOLECULAR WEIGHT AΒ1-42 OLIGOMER-INDUCED NEUROTOXICITY ONMITOCHONDRIA2021
- Author(s)
  Atsushi Kimura, Yuji Kiuchi, Mayumi Tsuji, Kenjiro Ono
- Organizer
  The 15th International Conference on Alzheimer's & Parkinson's diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] Aβを中心とするアプローチ2020
- Author(s)
  小野賢二郎
- Organizer
  第38回日本神経治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] パーキンソン病における睡眠障害の頻度とその対応2020
- Author(s)
  兼元みずき、矢野怜、稗田宗太郎、小野賢二郎
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] ビタミンB12は、アミロイドβオリゴマーによる神経毒性を抗酸化作用により抑制する2020
- Author(s)
  木村篤史,安本太郎, 森友紀子, 小口達敬, 海野真一, 海野麻未, 中村史朗, 井上富雄, 山田正仁, テプロフ D.B., 辻まゆみ, 小野賢二郎, 木内祐二
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-20K11266
[Presentation] 中島町研究に基づく認知症予防開発の取り組み2020
- Author(s)
  篠原もえ子、濵口毅、小野賢二郎、山田正仁
- Organizer
  第35回日本老年精神医学会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naive Parkinson's disease2020
- Author(s)
  Ono Kenjiro、Murakami Hidetomo、Tokuda Takahiko、El-Agnaf Omar M. A.、Ohmichi Takuma、Miki Ayako、Ohashi Hideaki、Owan Yoshiyuki、 Saito Yu、Yano Satoshi、Tsukie Tamao、Ikeuchi Takeshi
- Organizer
  Alzheimer's Association International Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] High molecular weight Amyloid β oligomer induces disruption and structural change of cell membrane2020
- Author(s)
  安本太郎、高村雄策、辻まゆみ、中山隆宏、今村恵子、井上治久、中村史朗、井上富雄、木村篤史、矢野怜、西条寿夫、木内祐二、Teplow David B.、小野賢二郎
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Relationship between Cerebral Microbleeds, Ventricular Enlargement and White Matter Hyperintensities in Alzheimer’s Disease2020
- Author(s)
  Kuroda Takeshi、Honma Motoyasu、Mori Yukiko、Futamura Akinori、Sugimoto Azusa、Yano Satoshi、Kinno Ryuta、Murakami Hidetomo、Ono Kenjiro
- Organizer
  Alzheimer's Association International Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Vitamin B12 may prevent Aβ oligomer-induced neurotoxicity in Alzheimer's Disease2020
- Author(s)
  Kimura Atsushi M.、Yasumoto Taro、Mori Yukiko、Oguchi Tatsunori、Umino Masakazu、Umino Asami、 Nakamura Shiro、Inoue Tomio、Yamada Masahito、Teplow David B.、Kiuchi Yuji、Tsuji Mayumi、Ono Kenjiro
- Organizer
  Alzheimer’s Association International Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アルツハイマー病の疾患修飾療法の展望2020
- Author(s)
  小野賢二郎
- Organizer
  第50回日本神経精神薬理学会年会、第42回日本生物学的精神医学会年会、第4回日本精神薬学会総会・学術集会（NPBPPP合同年会）
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 超高齢発症の認知症疾患2020
- Author(s)
  小野賢二郎
- Organizer
  第61回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] High molecular weight amyloid β1-42 oligomers induce neurotoxicity via plasma membrane damage2020
- Author(s)
  Taro Yasumoto, Yusaku Takamura, Mayumi Tsuji, Takahiro Nakayama, Keiko Imamura, Haruhisa Inoue, Shiro Nakamura, Tomio Inoue, Atsushi Kimura, Satoshi Yano, Hisao Nishijo, Yuji Kiuchi, David B Teplow, and Kenjiro Ono
- Organizer
  2020 Alzheimer's Association International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] HMW Aβ oligomers are important targets for disease modifying approach of Alzheimer's disease2020
- Author(s)
  小野賢二郎
- Organizer
  第61回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] ビタミンB12はアミロイドβオリゴマーによる神経毒性を抗酸化作用により抑制する2020
- Author(s)
  木村篤史、安本太郎、森友紀子、小口達敬、海野真一、海野麻未、中村史朗、井上富雄、辻まゆみ、木内祐二、小野賢二郎
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] ADとDLBの脳血流SPECTの有用性2020
- Author(s)
  二村明徳、稗田宗太郎、森友紀子、春日健作、杉本あずさ、笠井英世、黒田岳志、矢野怜、池内健、小野賢二郎
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 腸内微生物叢由来フェノール化合物の病態蛋白凝集制御効果2020
- Author(s)
  小野賢二郎
- Organizer
  第38回日本神経治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Aβオリゴマーに焦点を当てたアルツハイマー病の疾患修飾へのアプローチ2020
- Author(s)
  小野賢二郎
- Organizer
  第39回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アルツハイマー病の疾患修飾療法のターゲットとしてのプロトフィブリル2020
- Author(s)
  小野賢二郎
- Organizer
  第63回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Myricetin prevents Aβ oligomer-induced neurotoxicity via cell membrane damage2020
- Author(s)
  Atsushi Kimura, Taro Yasumoto, Yuko Mori, Tatsunori Oguchi, Shiro Nakamura, Tomio Inoue, M Yamada, D.Teplow, Kenjiro Ono, Mayumi Tsuji, Yuji Kiuchi
- Organizer
  The 14th International Conference on Alzheimer's & Parkinson's diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] アルツハイマー病と正常圧水頭症の鑑別における脳脊髄液バイオマーカーの有用性2020
- Author(s)
  黒田岳志、森友紀子、二村明徳、杉本あずさ、笠井英世、矢野怜、稗田宗太郎、春日健作、池内健、小野賢二郎
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Melissa officinalis extract containing rosmarinic acid for Alzheimer’s disease2020
- Author(s)
  篠原もえ子、小野賢二郎、濵口毅、永井俊匡、小林彰子、小松潤史、横濱美晴、岩佐和夫、山田正仁
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 認知症治療の知アルツハイマー病の疾患修飾療法の展望2020
- Author(s)
  小野賢二郎
- Organizer
  第40回日本脳神経外科コングレス総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] αシヌクレイン凝集の動的観察2020
- Author(s)
  小野賢二郎
- Organizer
  第61回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 認知症に挑む認知症の疾患修飾療法への光は見えるか？2020
- Author(s)
  小野賢二郎
- Organizer
  第63回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Advances in the Diagnosis of Parkinson's disease (Up-to-date)2020
- Author(s)
  Ono Kenjiro
- Organizer
  Chinese Society of Microcirculation Neurodegenerative Diseases Committee
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] α-シヌクレイン凝集に焦点をあてたパーキンソン病の疾患修飾へのアプローチ2020
- Author(s)
  小野賢二郎
- Organizer
  第38回日本神経治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] AD病態に即した疾患修飾へのアプローチ2020
- Author(s)
  小野賢二郎
- Organizer
  第63回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 糖尿病と認知症2020
- Author(s)
  小野賢二郎
- Organizer
  第35回日本糖尿病合併症学会、第26回日本糖尿病眼学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] レビー小体病：疾患修飾へのアプローチ2020
- Author(s)
  小野賢二郎
- Organizer
  日本脳神経外科学会第79回学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] High molecular weight amyloid β1-42 oligomers induce neurotoxicity via plasma membrane damage2020
- Author(s)
  Yasumoto Taro、Takamura Yusaku、Tsuji Mayumi、Watanabe-Nakayama Takahiro、Imamura Keiko、Inoue Haruhisa、Nakamura Shiro、Inoue Tomio、Kimura Atsushi、Yano Satoshi、Nishijo Hisao、Kiuchi Yuji、Teplow David B.、Ono Kenjiro
- Organizer
  Alzheimer's Association International Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 高分子Aβオリゴマーは細胞膜完全性を崩壊し細胞毒性を発揮する2020
- Author(s)
  安本太郎，高村雄策，辻まゆみ，中山隆宏，今村恵子，井上治久，中村史朗，井上富雄，木村篤史，矢野怜，西条寿夫，木内祐二，デービッドテプロフ，小野賢二郎
- Organizer
  第39回　日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] Myricetin prevents Aβ oligomers-induced neurotoxicity via cell membrane damage2020
- Author(s)
  Kimura Atsushi M.、Yasumoto Taro、Mori Yukiko、Oguchi Tatsunori、Umino Masakazu、Umino Asami、Nakamura Shiro、Inoue Tomio、Yamada Masahito、Teplow David B.、Kiuchi Yuji、Tsuji Mayumi、Ono Kenjiro
- Organizer
  15th International Conference on Alzheimer’s and Parkinson’s Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Prevention of dementia from a population-based cohort study in Nakajima, Japan2020
- Author(s)
  山田正仁、篠原もえ子、小野賢二郎、濵口毅
- Organizer
  第39回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] サプリメントに焦点を当てたアルツハイマー病に対する疾患修飾へのアプローチ2020
- Author(s)
  小野賢二郎
- Organizer
  第2回日本脳サプリメント学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アルツハイマー型認知症におけるアミロイド仮説を再考する2020
- Author(s)
  小野賢二郎
- Organizer
  第35回日本老年精神医学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アルツハイマー病と正常圧水頭症の鑑別: 脳脊髄液Aβ1-42/1-40, Aβ1-42/1-38比の有用性2020
- Author(s)
  黒田岳志、二村明徳、森友紀子、杉本あずさ、矢野怜、稗田宗太郎、春日健作、池内健、小野賢二郎
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] ミリセチンは抗酸化作用を介し、ミトコンドリア・細胞膜でアミロイドβオリゴマーによる神経毒性を抑制する2020
- Author(s)
  木村篤史、森友起子、小口達敬、海野真一、海野麻未、宇高結子、中村史朗、井上富雄、辻まゆみ、小野賢二郎、木内祐二
- Organizer
  第39回　日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] 高分子 Aβオリゴマーは細胞膜完全性を崩壊し細胞毒性を発揮する2020
- Author(s)
  安本太郎、高村雄策、辻まゆみ、中山隆宏、今村恵子、井上治久、中村史朗、井上富雄、木村篤史、矢野怜、西条寿夫、木内祐二、Teplow David B.、小野賢二郎
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 嚥下障害を伴った AICA 症候群の 65 歳男性例2019
- Author(s)
  加藤悠太、栗城綾子、福田早織、和田隆秀、藤井隆史、小室浩康、田中健一郎、宮内淑史、神谷雄己、小野賢二郎
- Organizer
  第231回日本神経学会関東・甲信越地方会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アルツハイマー病：疾患修飾へのアプローチ2019
- Author(s)
  小野賢二郎
- Organizer
  第24回日本神経精神医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 高分子Aβオリゴマーは細胞膜傷害を介して神経細胞毒性を発揮する2019
- Author(s)
  安本太郎、高村雄策、辻まゆみ、中山隆、今村恵子、井上治久、中村史朗、井上富雄、木村篤史、矢野怜、西条寿夫、木内祐二、デービッド・テプロフ、小野賢二郎
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 中咽頭癌の経過中に発症した A 群溶血性連鎖球菌性髄膜炎の一例2019
- Author(s)
  和田隆秀、宮内淑史、加藤悠太、藤井隆史、福田早織、小室浩康、栗城綾子、神谷雄己、小野賢二郎
- Organizer
  第230回日本神経学会関東・甲信越地方会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] シヌクレイノパチーの病態に基づいた疾患修飾へのアプローチ2019
- Author(s)
  小野賢二郎
- Organizer
  第37回日本神経治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アルツハイマー型認知症, 軽度認知障害における甲状腺機能と脳血流量の関連の検討2019
- Author(s)
  野元祥平、金野竜太、森友紀子、二村明徳、杉本あずさ、黒田岳志、矢野怜、村上秀友、落合裕隆、小風暁、小野賢二郎
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Alzheimer's disease: The Approach for disease modification2019
- Author(s)
  Ono K
- Organizer
  6th Congress of Asian College of Neuropsychopharmacology (AsCNP) 29th Annual Meeting of Japanese Society of Clinical Neuropsychopharmacology (JSCNP)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 認知症に挑む2019
- Author(s)
  小野賢二郎
- Organizer
  日本情動学会第9回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Homoglobin and hematocrit levels are sensitive to functional imaging abnormalities in patients with memory loss2019
- Author(s)
  Yano S, kinno R, Futamura A, Shiromaru A, Kuroda T, Murakami H, Ono K
- Organizer
  Alzheimer's Association International Conference 2019(AAIC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Trousseau 症候群に伴う脳梗塞における直接経口抗凝固薬の有用性についての検討2019
- Author(s)
  小菅将太、黒田岳志、小口達敬、二村明徳、小野賢二郎
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Lacosamide が奏功した発作性運動誘発性舞踏アテトーシスの 24 歳女性例2019
- Author(s)
  井藤尚仁、笠井英世、柿沼佑樹、高見礼示、栄良樹、杉本あずさ、稗田宗太郎、小野賢二郎
- Organizer
  第231回日本神経学会関東・甲信越地方会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] もの忘れ外来における超高齢初診患者の傾向と神経原線維型老年期認知症の可能性2019
- Author(s)
  稗田宗太郎、二村明徳、杉本あずさ、笠井英世、黒田岳志、矢野怜、小野賢二郎
- Organizer
  第60回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] フェノール化合物に焦点を当てたアルツハイマー病に対する疾患就職へのアプローチ2019
- Author(s)
  小野賢二郎
- Organizer
  第9回日本認知症予防学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] High molecular weight amyloid β1-42 oligomers induce neurotoxicity via plasma membrane damage2019
- Author(s)
  Ono K, Yasumoto T, Takamura Y, Tsuji M, Watanabe-Nakayama T, Imamura K, Inoue H, Nakamura S, Inoue T, Kimura A, Yano S, Nishijo H, Kiuchi Y, Teplow DB
- Organizer
  The Protein Aggregation Conference: From Structure to In Vivo Sequelae,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アルツハイマー病発症機序解明の現状と先制医療の展望2019
- Author(s)
  小野賢二郎
- Organizer
  第10回日本脳血管・認知症学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 大動脈可動性巨大病変が抗凝固療法により消失した急性期脳梗塞の 53 歳女性例2019
- Author(s)
  水間啓太、栗城綾子、福田早織、藤井隆史、小室浩康、井藤尚仁、宮内淑史、神谷雄己、小野賢二郎
- Organizer
  第38回日本脳神経超音波学会総会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 病理学的に免疫性機序の関与が想定された再発性高 CK 血症を伴った視神経脊髄炎の一例2019
- Author(s)
  金野竜太、刑部祐友子、高橋聖也、黒川信二、大湾喜行、清水潤、小野賢二郎、馬場康彦
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] ニボルマブに誘発された筋炎の 70 歳男性例2019
- Author(s)
  森友紀子、石田敦士、浅野未希、栄良樹、齋藤悠、黒田岳志、稗田宗太郎、小野賢二郎
- Organizer
  第230回日本神経学会関東・甲信越地方会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] ボランティア活動は認知症患者の社会参加の機会となり得るか2019
- Author(s)
  森友紀子、宮之原麻衣、二村明徳、杉本あずさ、笠井英世、黒田岳志、矢野怜、稗田宗太郎、小野賢二郎
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 生体弁弁輪部膿瘍を合併した脳膿瘍の一例2019
- Author(s)
  藤井隆史、栗城綾子、加藤悠太、和田隆秀、福田早織、小室浩康、宮内淑史、神谷雄己、水間啓太、小野賢二郎
- Organizer
  第229回日本神経学会関東・甲信越地方会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 大動脈粥腫の長期観察における経時的変化：可動性粥腫と粥腫厚, 潰瘍長の関連2019
- Author(s)
  栗城綾子、神谷雄己、藤井隆史、福田早織、井藤尚仁、小室浩康、水間啓太、宮内淑史、小野賢二郎
- Organizer
  第38回日本脳神経超音波学会総会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] パーキンソン病患者における MIBG 心筋シンチグラフィと左室拡張能との関連2019
- Author(s)
  大湾喜行、高橋聖也、刑部祐友子、黒川信二、金野竜太、小野賢二郎、馬場康彦
- Organizer
  第13回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Effects of vitamin B12 on memory function in elderly patients2019
- Author(s)
  木村篤史、金野竜太、二村明徳、野元祥平、久保田怜美、森友紀子、杉本あずさ、黒田岳史、矢野怜、村上秀友、小野賢二郎
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 高位内頸動脈の不安定プラークに対して経口腔頸部血管超音波検査での経時的変化を観察した 57 歳男性例2019
- Author(s)
  福田早織、栗城綾子、水間啓太、三木綾子、和田隆秀、加藤悠太、藤井隆史、小室浩康、宮内淑史、神谷雄己、小野賢二郎
- Organizer
  第22回日本栓子検出と治療学会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 高分子Aβオリゴマーは細胞膜傷害を介して神経細胞毒性を発揮する2019
- Author(s)
  安本太郎、高村雄策、辻まゆみ、中山隆宏、今村恵子、井上治久、中村史朗、井上富雄、木村篤史、矢野怜、西条寿夫、木内祐二、デービッド・テプロフ、小野賢二郎
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] 片頭痛患者における痛み刺激による不安呼吸関連電位とその電源推定2019
- Author(s)
  笠井英世、政岡ゆり、小野賢二郎、泉崎雅彦、本間生夫
- Organizer
  第9回日本情動学会大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Supratherapeutic concentrations of cilostazol inhibits β-amyloid oligomerization in vitro.2019
- Author(s)
  Ono K, Shozawa H, Oguchi T, Tsuji M, Yano S, Kiuchi Y
- Organizer
  Alzheimer's Association International Conference 2019(AAIC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] もの忘れ外来における超高齢初診患者の傾向と神経原線維型老年期認知症の可能性2019
- Author(s)
  稗田宗太郎、森友紀子、二村明徳、杉本あずさ、笠井英世、黒田岳志、矢野怜、小野賢二郎
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アルツハイマー型認知症　疾患修飾へのアプローチを考える2019
- Author(s)
  小野賢二郎
- Organizer
  第38回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Effects of vitamin B12 on memory fuction in elderly patients2019
- Author(s)
  Atsushi Kimura, Ryuta Kinno, Akinori Futamura, Shohei Nomoto, Satomi Kubota, Yukiko Mori, Azusa Sugimoto, Takeshi Kuroda, Satoshi Yano, Hidetomo Murakami, Mayumi Tsuji, Kenjiro Ono
- Organizer
  60th Annual Meeting of the Japanese Society of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] もの忘れ外来における超高齢初診患者の傾向と神経原線維型老年期認知症の可能性2019
- Author(s)
  稗田宗太郎、森友紀子、二村明徳、杉本あずさ、笠井英世、黒田岳志、矢野怜、小野賢二郎
- Organizer
  第37回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 脳梗塞を契機に発見された成人単純型大動脈縮窄症の 1 例2019
- Author(s)
  石田敦士、小菅将太、浅野未希、大橋英朗、森友紀子、笠井英世、稗田宗太郎、小野賢二郎
- Organizer
  第229回日本神経学会関東・甲信越地方会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 淡蒼球性認知症―睡眠時無呼吸症候群を背景とした 1 例と文献レビュー2019
- Author(s)
  杉本あずさ、水間啓太、正路大樹、門馬佑太郎、所澤任修、稗田宗太郎、小野賢二郎
- Organizer
  第9回日本情動学会大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 慢性閉塞性肺疾患患者における海馬サブ領域体積の測定2019
- Author(s)
  飯塚奈都子、政岡ゆり、井田正博、眞鍋亮、吉田正樹、吉川輝、小岩信義、久保田怜美、本間元康、小野賢二郎、泉崎雅彦
- Organizer
  第47回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 右脳静脈洞塞栓後の顔中心部の相貌変形視例2019
- Author(s)
  二村明徳、小山慎一、大橋英朗、三木綾子、小口達敬、小野賢二郎
- Organizer
  第24回日本神経精神医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] パーキンソン病の運動症状と重心動揺計の計測結果との関連について2019
- Author(s)
  大湾喜行、刑部祐友子、高橋聖也、黒川信二、金野竜太、馬場康彦、村上秀友、小野賢二郎
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アルツハイマー病における脳小血管病と脳脊髄液循環障害の関連について2019
- Author(s)
  黒田岳志、小菅将太、小口達敬、森友紀子、二村明徳、杉本あず、矢野怜、金野竜太、村上秀友、小野賢二郎
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 原子間力顕微鏡および電子顕微鏡によるアミロイド構成蛋白質凝集の観察2019
- Author(s)
  小野賢二郎
- Organizer
  医学生物学電子顕微鏡技術学会第35回学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 高齢者における脳局所体積と認知機能・嗅覚機能2019
- Author(s)
  久保田怜美、政岡ゆり、飯塚奈都子、眞鍋亮、吉川輝、吉田正樹、金野竜太、井田正博、小野賢二郎、泉崎雅彦
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 中咽頭癌の経過中に発症した A 群溶血性連鎖球菌性髄膜炎の一例2019
- Author(s)
  和田隆秀、宮内淑史、加藤悠太、藤井隆史、福田早織、小室浩康、栗城綾子、神谷雄己、小野賢二郎
- Organizer
  第24回日本神経感染症学会総会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 外因性アミロイド蛋白のアミロイドβ蛋白凝集へのクロス・シーディング効果2016
- Author(s)
  小野賢二郎、高橋良一、池田篤平、水口峰之、浜口毅、山田正仁
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京）
- Year and Date
  2016-08-19
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー型認知症の診断と治療2016
- Author(s)
  小野賢二郎
- Organizer
  第146回日本神経学会東海北陸地方会
- Place of Presentation
  石川県地場産業振興センター（金沢）
- Year and Date
  2016-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー型認知症の診断と治療2016
- Author(s)
  小野賢二郎
- Organizer
  第55回全国自治体病院学会
- Place of Presentation
  富山県民会館/富山第一ホテル（富山）
- Year and Date
  2016-10-20
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 早期凝集体に焦点を当てたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アミロイド仮説に基づいたアルツハイマー型認知症予防・治療薬開発2016
- Author(s)
  小野　賢二郎
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 関東地区推薦講演：Aβ凝集に焦点をあてたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第30回老年期認知症研究会
- Place of Presentation
  コクヨホール（東京）
- Year and Date
  2016-07-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Parkinson 病初発例の運動症状に対するドパミン作動薬の効果と DAT スキャン所見との関連2016
- Author(s)
  村上秀友、石垣征一郎、加藤大貴、小野賢二郎
- Organizer
  第34回日本神経治療学会総会
- Place of Presentation
  米子コンベンションセンター/米子市文化ホール（米子）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Aβ凝集過程と阻害薬開発2016
- Author(s)
  小野賢二郎
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京）
- Year and Date
  2016-08-19
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] オリゴマオパチーとしてのアルツハイマー病2016
- Author(s)
  小野賢二郎
- Organizer
  第21回日本神経感染症学会総会学術大会
- Place of Presentation
  金沢東急ホテル（金沢）
- Year and Date
  2016-10-21
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 進行性非流暢性/失文法性失語の脳血流部位に関する研究2016
- Author(s)
  金野竜太、黒川信二、大湾喜行、二村明憲、四郎丸あずさ、笠井英世、黒田岳志、矢野怜、石垣征一郎、村上秀友、小野賢二郎
- Organizer
  第21回日本神経精神医学会
- Place of Presentation
  くまもと県民交流館パレア（熊本）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 高速原子力間顕微鏡を用いたAβ42凝集過程の観察2016
- Author(s)
  小野賢二郎、中山隆宏、伊丹将大、高橋良一、David Teplow、山田正仁
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Exogenous amyloid proteins function as seeds in amyloid β-protein aggregation2016
- Author(s)
  小野賢二郎、高橋良一、池田篤平、水口峰之、浜口毅、山田正仁
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病におけるCAA関連微小出血と脳脊髄液バイオマーカーとの関連2016
- Author(s)
  篠原もえ子、小松潤史、佐村木美晴、松成一朗、池田篤平、坂井健二、濱口毅、小野賢二郎、山田正仁
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] オリゴマー仮説に基づいたアルツハイマー型認知症治療薬の研究2016
- Author(s)
  小野賢二郎
- Organizer
  第7回日本脳血管・認知症学会学術大会
- Place of Presentation
  金沢都ホテル（金沢）
- Year and Date
  2016-08-06
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー型認知症の診断と治療2016
- Author(s)
  小野賢二郎
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 2015年度日本神経学会賞受賞講演：フェノール化合物に焦点をあてたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Exogenous amyloidogenic proteins function as seeds in Aβ aggregation2016
- Author(s)
  Ono K, Takahashi R, Ikeda T, Mizuguchi M, Hamaguchi T, Yamada M
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego convention center（アメリカ）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 2016年度日本神経化学会優秀賞受賞講演：オリゴマー仮説に基づいたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第59回日本神経化学会大会・第38回日本生物学的精神医学会合同年会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2016-09-08
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 123I-Ioflupane SPECT predicts the efficacy of selegiline monotherapyfor motor symptoms in drug-naive Parkinson's disease2016
- Author(s)
  Murakami H, Ishigaki S, Katoh H, Ono K
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego convention center（アメリカ）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病における脳アミロイドアンギオパチー関連微小出血と脳脊髄液バイオマーカーとの関連2016
- Author(s)
  佐村木美晴、松成一朗、吉田光宏、島啓介、篠原もえ子、濱田毅、小野賢二郎、山田正仁
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京）
- Year and Date
  2016-08-19
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] オリゴマー仮説に基づいたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-07-20
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 非薬物学的アプローチからアルツハイマー型認知症を考える2016
- Author(s)
  小野賢二郎
- Organizer
  第11回日本リハビリテーション医学会専門医会学術集会
- Place of Presentation
  金沢市文化ホール（金沢）
- Year and Date
  2016-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病における微小出血と脳脊髄液バイオマーカーとの関連2016
- Author(s)
  篠原もえ子、小松潤史、佐村木美晴、松成一朗、池田篤平、坂井健二、濱田毅、小野賢二郎、山田正仁
- Organizer
  第7回日本脳血管・認知症学会学術大会
- Place of Presentation
  金沢都ホテル（金沢）
- Year and Date
  2016-08-06
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病における脳アミロイドアンギオパチー関連微小出血と脳糖代謝・灰白質容量との関係2016
- Author(s)
  佐村木美晴、松成一朗、吉田光宏、島啓介、篠原もえ子、濱口毅、小野賢二郎、山田正仁
- Organizer
  第7回日本脳血管・認知症学会学術大会
- Place of Presentation
  金沢都ホテル（金沢）
- Year and Date
  2016-08-06
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 食品関連因子による認知症予防・治療法の開発2016
- Author(s)
  山田正仁、篠原もえ子、小野賢二郎、浜口毅
- Organizer
  第58回日本老年医学会学術集会
- Place of Presentation
  石川県立音楽堂/ANAクラウンプラザホテル/金沢アートホール（金沢）
- Year and Date
  2016-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病の病態研究の最前線：オリゴマーの実体とは何か？2016
- Author(s)
  小野賢二郎
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Effects of Antiparkinsonian Agents on β-amyloid and α-synuclein Oligomer Formarion in vitro.2015
- Author(s)
  Ono K, Takasaki J-I, Takahashi R, Ikeda T, Yamada M.
- Organizer
  Neuroscience 2015
- Place of Presentation
  Chicago
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 現在のAD治療と予防・治療薬の開発2015
- Author(s)
  小野　賢二郎
- Organizer
  第39回日本高次脳機能障害学会学術総会
- Place of Presentation
  ベルサール渋谷ファースト（東京）
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 外因性アミロイド蛋白のアミロイドβ蛋白凝集へのクロス・シーディング効果2015
- Author(s)
  小野　賢二郎、高橋良一、池田篤平、水口峰之、浜口毅、山田正仁
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーション青森（青森）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Positioning of early aggregates of Aβ in its aggregation process2015
- Author(s)
  小野　賢二郎、中山　隆宏、山田　正仁
- Organizer
  第56回日本神経学会学術集会
- Place of Presentation
  朱鷺メッセ(新潟)
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 有機化合物に焦点をあてたαシヌクレイン凝集抑制薬の開発2015
- Author(s)
  小野　賢二郎、高橋　良一，山田　正仁
- Organizer
  第56回日本神経学会学術集会
- Place of Presentation
  朱鷺メッセ(新潟)
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 病態に基づいたアルツハイマー型認知症の予防・治療薬開発2015
- Author(s)
  小野　賢二郎
- Organizer
  第25回日本医療薬学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アミロイドβ蛋白とα-シヌクレイン蛋白のクロス・シーディング効果2014
- Author(s)
  小野賢二郎、高橋良一、池田篤平、山田正仁
- Organizer
  第2回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京）
- Year and Date
  2014-08-22
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 第10回十全医学賞受賞記念講演　フェノール化合物に焦点をあてたアルツハイマー病の予防・治療薬開発2014
- Author(s)
  小野賢二郎
- Organizer
  平成26年度金沢大学十全医学会学術集会
- Place of Presentation
  金沢大学十全講堂（金沢）
- Year and Date
  2014-06-24
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Vitamin A, Phenolic Compounds, and Alzheimer's Disease2013
- Author(s)
  Ono K
- Organizer
  Conference on Health Aging in Asia
- Place of Presentation
  Grand Copthorne Waterfront (Singapore)
- Invited
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] フェノール化合物は特異的結合によってAβオリゴマー形成及びシナプス毒性を抑制する2012
- Author(s)
  小野賢二郎,Lei Li,高村雄策,吉池裕二,池田篤平,西条寿夫,高島明彦, David B Teplow, Michael G Zagorski,山田正仁
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば国際会議場(茨城県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Vitamin A inhibits Aβ oligomerization in vitro2012
- Author(s)
  Ono K, Takasaki J, Yoshiike Y, Hirohata M, Ikeda T, Morinaga A, Takashima A, Yamada M
- Organizer
  第35回日本神経科学大会 Neuroscience 2012
- Place of Presentation
  名古屋国際会議場(愛知県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] NSAIDsはβアミロイド蛋白オリゴマー形成抑制作用およびシーディング抑制作用を有する2012
- Author(s)
  廣畑美枝,小野賢二郎,高崎純一,森永章義,池田篤平,山田正仁
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Vitamin A has anti-oligomerization effects on amyloid-β in vitro2012
- Author(s)
  Ono K
- Organizer
  Alzheimer’s Association International Conference on Alzheimer’s Disease 2012
- Place of Presentation
  Vancouver Convention Center (Canada)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] ビタミンAによるAβオリゴマー形成抑制効果2012
- Author(s)
  小野賢二郎
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 有機化合物に焦点をあてたアルツハイマー病の予防・治療薬の開発2012
- Author(s)
  小野賢二郎
- Organizer
  第54回日本老年医学会学術集会ノバルティス老化および老年医学研究基金受賞講演
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Anti-Amyloidogenic Effects of lsoflavones In Vitro: Fluorescence Spectroscopy Demonstrating Direct Interractions Between Isoflavones and Aβs2012
- Author(s)
  Hirohata M, Ono K, Takasaki J, Yamada M
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2012
- Place of Presentation
  Vancouver Convention Center (Canada)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 有機化合物に焦点をあてたアルツハイマー病の予防・治療薬の開発2012
- Author(s)
  小野賢二郎
- Organizer
  第54回日本老年医学会学術集会　ノバルティス老化および老年医学研究基金受賞講演
- Place of Presentation
  東京国際フォーラム（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Vitamin A has anti-oligomerization effects on amyloid-β in vitro2012
- Author(s)
  Ono K, Takasaki J, Yoshiike Y, Hirohata M, Ikeda T, Morinaga A, Takashima A, Yamada M
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2012
- Place of Presentation
  Vancouver Convention Center (Canada)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] ビタミンAによるAβオリゴマー形成抑制効果2012
- Author(s)
  小野賢二郎,高崎純一,吉池裕二,廣畑美枝,池田篤平,森永章義,高島明彦,山田正仁
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Vitamin A inhibits Aβ oligomerization in vitro2012
- Author(s)
  Ono K
- Organizer
  第35回日本神経科学大会　Neuroscience 2012
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] フェノール化合物は特異的結合によってAβオリゴマー形成及びシナプス毒性を抑制する2012
- Author(s)
  小野賢二郎
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば国際会議場（茨城県）
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] イソフラボンのβアミロイド蛋白モノマー・オリゴマー・線維への作用の検討2012
- Author(s)
  廣畑美枝,小野賢二郎,高崎純一,高橋良一,池田篤平,森永章義,山田正仁
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば国際会議場(茨城県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 家族性アミロイドポリニューロパチーの凝固・線溶異常2012
- Author(s)
  高橋良一,小野賢二郎,池田篤平,赤木明生,能登大介,野崎一朗,坂井健二,朝倉英策,岩佐和夫,山田正仁
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Low order-oligomers as therapeutic targets of Alzeheimer's disease2012
- Author(s)
  Ono K
- Organizer
  Neuroscience Seminar in University of British Columbia
- Place of Presentation
  University of British Columbia (Canada)
- Year and Date
  2012-07-17
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English (H6R) 及び Tottori (D7N) 変異アミロイドβ蛋白の凝集および細胞毒性2011
- Author(s)
  小野賢二郎,David B Teplow,山田正仁
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English (H6R) 及び Tottori 型(D7N)変異アミロイドβ蛋白の凝集および細胞毒性2011
- Author(s)
  小野賢二郎,David B Teplow,山田正仁
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  タワーホール船堀(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アルツハイマー病βアミロイド蛋白凝集機構解明から予防・治療薬開発へ2011
- Author(s)
  小野賢二郎
- Organizer
  第54回日本神経化学大会ミニランチョンセミナー
- Place of Presentation
  瑠璃光(石川県)(招待講演)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English(H6R)及びTottori(D7N)変異アミロイドβ蛋白の凝集および細胞毒性2011
- Author(s)
  小野賢二郎、Teplow. DB、山田正仁
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English(H6R)及びTottori(D7N)型変異がアミロイドβ蛋白の凝集および細胞毒性に与える影響2011
- Author(s)
  小野賢二郎、Teplow. DB、山田正仁
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English(H6R)及びTottori型(D7N)変異アミロイドβ蛋白の凝集および細胞毒性2011
- Author(s)
  小野賢二郎、Teplow. DB、山田正仁
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Low-n oligomers as therapeutic targets of Alzeheimer's disease2011
- Author(s)
  Ono K
- Organizer
  Neuroscience Seminar in University of Groningen
- Place of Presentation
  University of Groningen(Netherlands)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Low-n oligomers as therapeutic targets of Alzeheimer's disease2011
- Author(s)
  Ono. K
- Organizer
  Neuroscience Seminar in University of Groningen
- Place of Presentation
  University of Groningen (Netherlands)(招待講演)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Effect of melatonin on α-synuclein self-assembly and cytotoxicity2011
- Author(s)
  Ono K, Mochizuki H, Ikeda T, Nihira T, Takasaki J, Teplow DB, Yamada M
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2011
- Place of Presentation
  Expo in Porte de Versailles(France)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English (H6R) 及び Tottori (D7N) 型変異がアミロイドβ蛋白の凝集および細胞毒性に与える影響2011
- Author(s)
  小野賢二郎,David B Teplow,山田正仁
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Effect of melatonin on α-synuclein self-assembly and cytotoxicity2011
- Author(s)
  Ono. K, Mochizuki. H, Ikeda. T, Nihira. T, Takasaki. J, Teplow. DB, Yamada. M
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2011
- Place of Presentation
  Expo in Porte de Versailles (France)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アルツハイマー病βアミロイド蛋白凝集機構解明から予防・治療薬開発へ2011
- Author(s)
  小野賢二郎
- Organizer
  第54回日本神経化学大会ミニランチョンセミナー
- Place of Presentation
  瑠璃光(石川県)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Aβ凝集機構解明から予防・治療薬開発へ2010
- Author(s)
  小野賢二郎
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  ウインクあいち(愛知県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Grape derived polyphenols attenuate tau neuropathology in the tmht mouse model of Alzheimer's disease2010
- Author(s)
  Wang J, Santa-Maria I, Ho L, Ksiezak-Reding H, Ono K, Teplow DB, Pasinetti GM
- Organizer
  Neuroscience Nanosymposium 2010
- Place of Presentation
  San Diego Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 神経変性疾患(特にアルツハイマー病、パーキンソン病)の予防・治療薬開発2010
- Author(s)
  小野賢二郎
- Organizer
  平成22年度昭和大学医学部同窓会学術講演会
- Place of Presentation
  昭和大学医学部(東京都)
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Aβ凝集機構解明から予防・治療薬開発へ2010
- Author(s)
  小野賢二郎
- Organizer
  第29回日本認知症学会学術集会シンポジウム5 認知症の阻止を狙った治療薬開発研究
- Place of Presentation
  ウインクあいち(名古屋)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Grape derived polyphenols attenuate tau neuropathology in the tmht mouse model of Alzheimer's disease2010
- Author(s)
  Wang. J, Santa-Maria. I, Ho. L, Ksiezak-Reding. H, Ono. K, Teplow. DB, Pasinetti. GM
- Organizer
  Neuroscience Nanosymposium 2010
- Place of Presentation
  コンベンションセンター(米国・サンディエゴ)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Structure-neurotoxicity analysis of amyloid β-protein oligomers2010
- Author(s)
  Ono. K, Teplow. DB, Condron. MM
- Organizer
  International Conference on Alzheimer's Disease 2010
- Place of Presentation
  コンベンションセンター(米国・ホノルル)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Structure-neurotoxicity relationships of amyloid β-protein oligomers2010
- Author(s)
  小野賢二郎, David B Teplow, 山田正仁
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  ウインクあいち(名古屋)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アミロイドβ蛋白オリゴマーの構造-毒性相関2010
- Author(s)
  小野賢二郎, Margaret M Condron, David B Teplow, 山田正仁
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 有機化合物に焦点を当てたアルツハイマー病の予防・治療薬の開発2010
- Author(s)
  小野賢二郎
- Organizer
  京都大学農学研究科大学院特別講義
- Place of Presentation
  京都大学(京都)
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 神経変性疾患(特にアルツハイマー病、パーキンソン病)の予防・治療薬開発2010
- Author(s)
  小野賢二郎
- Organizer
  平成22年度昭和大学医学部同窓会学術講演会
- Place of Presentation
  昭和大学医学部(東京)
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アミロイドβ蛋白オリゴマーの構造及び毒性相関の解析2010
- Author(s)
  小野賢二郎,David B Teplow,Margaret M Condron,山田正仁
- Organizer
  第33回日本神経科学大会 Neuro2010
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Structure-neurotoxicity analysis of amyloid β-protein oligomers.2010
- Author(s)
  Ono K, Teplow DB, Condron. MM
- Organizer
  International Conference on Alzheimer's Disease 2010
- Place of Presentation
  Hawaii Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Structure-neurotoxicity relationships of amyloid β-protein oligomers2010
- Author(s)
  小野賢二郎,David B Teplow,山田正仁
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  ウインクあいち(愛知県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 小野賢二郎,Margaret M Condron,David B Teplow,山田正仁2010
- Author(s)
  小野賢二郎,Margaret M Condron,David B Teplow,山田正仁
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アミロイドβ蛋白オリゴマーの構造及び毒性相関の解析2010
- Author(s)
  小野賢二郎, David B Teplow, Margaret M Condron, 山田正仁
- Organizer
  Neuro2010
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Cross-seeding effects of amyloid β-protein and α-synuclein
- Author(s)
  Ono K, Takahashi R, Ikeda T, Yamada M
- Organizer
  Alzheimer’s Association International Conference on Alzheimer’s Disease 2014
- Place of Presentation
  コペンハーゲン（デンマーク）
- Year and Date
  2014-07-12 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Cross-seeding effects of amyloid β-protein and α-synuclein
- Author(s)
  Ono K, Takahashi R, Ikeda T, Yamada M
- Organizer
  第37回日本神経科学大会　Neuroscience 2014
- Place of Presentation
  パシフィッコ横浜（横浜）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] バイオマーカーの視点からPDの認知障害を考える
- Author(s)
  小野賢二郎、山田正仁
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  パシフィッコ横浜（横浜）
- Year and Date
  2014-11-29 – 2014-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Cross-seeding effects of amyloid β-protein and α-synuclein
- Author(s)
  Ono K, Takahashi R, Ikeda T, Yamada M.
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Low order-oligomers as therapeutic targets of Alzeheimer’s disease
- Author(s)
  Ono. K
- Organizer
  Neuroscience Seminar in University of British Columbia
- Place of Presentation
  University of British Columbia (Canada)
- Invited
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 病態に基づいたAlzheimer 病の予防・治療薬の開発
- Author(s)
  小野賢二郎、山田正仁
- Organizer
  第32回日本神経治療学会総会
- Place of Presentation
  東京ドームホテル（東京）
- Year and Date
  2014-11-20 – 2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 抗パーキンソン病薬のアミロイドβ蛋白及びαシヌクレイン蛋白のオリゴマー形成抑制
- Author(s)
  小野賢二郎、高崎純一、高橋良一、池田篤平、山田正仁
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  パシフィッコ横浜（横浜）
- Year and Date
  2014-11-29 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-26461266

1. YAMADA Masahito (80191336)

# of Collaborated Projects: 4 results

# of Collaborated Products: 48 results
2. Hamaguchi Tsuyoshi (70452109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 辻まゆみ (40155544)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. NAKAYAMA Takahiro (00532821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. SAKAI Kenji (00572306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 小口江美子 (50102380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 木内祐二 (50204821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. HONMA Motoyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. YABE Yoshiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. UMEDA Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. HARA Akinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. MIDORIKAWA Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. YASUO Terao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. FUTAMURA Akinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. YOSHIKAWA Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SATO Noriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. KONNO Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. KODERA Noriyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. IKEDA Yoshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. KIMURA Noriyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 金野竜太

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
22. 篠原もえ子

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
23. 阿部啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 遠山育夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 柳沢大治郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 井上富雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 中村史朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 中山希世美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 望月文子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 今村恵子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 西条寿夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 池田篤平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
33. 森啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 富山貴美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 小林彰子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 中村裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
37. 中村雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
38. 佐野輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
39. 河村満

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 松田博史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 入江一浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 安藤敏夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 東海林幹夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 池田将樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 阿部康二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 松原悦朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ono kenjiro 小野 賢二郎

小野 賢二郎 オノ ケンジロウ

Ono Kenjiro 小野 賢二郎

ONO Kenjiro 小野 賢二郎

Research Projects

Research Products

Co-Researchers

高速原子間力顕微鏡を用いた凝集タンパクのクロス・シーディング効果の時空間的観察Principal Investigator

Principal Investigator

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Development and evaluation of a dementia prevention support program which is provided by the collaboration of community medicine welfare, utilizing the group exercise with musical therapy

Principal Investigator

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膜障害に焦点を当てた高分子Aβオリゴマーの毒性機序に関する検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

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アミロイドβ毒性阻害を標的としたアルツハイマー病発症予防健康食品成分の探索

Principal Investigator

Project Period (FY)

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Study on transmission of sporadic cerebral amyloid angiopathy

Principal Investigator

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The elucidation of Abeta aggregation mechanism using high-speed atomic force microscopyPrincipal Investigator

Principal Investigator

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A study on propagation of cerebral b-amyloidosis with protein contained in foods and cosmetics

Principal Investigator

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Study on possible transmission of Alzheimer's disease with medical procedures and food

Principal Investigator

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Analysis of the effect of human living specimen on amyloid β-protein oligomerizationPrincipal Investigator

Principal Investigator

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生体分子及び有機化合物のαーシヌクレイン凝集に及ぼす影響の解析Principal Investigator

Principal Investigator

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Research Institution

[Book] 脳神経疾患最新の治療2021-20232021

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Total Pages

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Data Source

[Book] Annual Review 神経20212021

Author(s)

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[Book] 今日の治療指針 2021年版［デスク判］2021

Author(s)

Total Pages

ono kenjiro 小野賢二郎

小野賢二郎オノケンジロウ

Ono Kenjiro 小野賢二郎

ONO Kenjiro 小野賢二郎

[Book] 今日の診断指針デスク判第8版2020

[Journal Article] 認知症診療の知　アルツハイマー病の疾患修飾療法の展望2021

[Journal Article] 神経変性疾患の動物モデルの実験的治療：腸内微生物叢由来フェノール化合物のα-シヌクレイン凝集抑制効果2021