ono kenjiro 小野賢二郎

… Alternative Names

Researcher Number	70377381
Other IDs
External Links
Affiliation (Current)	2020: 昭和大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019: 昭和大学, 医学部, 教授 2015 – 2017: 昭和大学, 医学部, 教授 2016: 金沢大学, 附属病院, 講師 2014: 金沢大学, 大学病院, 講師 2012: 金沢大学, 大学病院, 講師 … More
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Neurology / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator アミロイドβ蛋白 / オリゴマー / アルツハイマー病 / レビー小体病 / α-シヌクレイン / チオフラビンS / 電子顕微鏡 / 原子間力顕微鏡 / 脳神経疾患 / 認知症 / 高速原子間力顕微鏡 / 毒性 … More Except Principal Investigator … More

膜障害に焦点を当てた高分子Aβオリゴマーの毒性機序に関する検討Principal InvestigatorOngoing
- Principal Investigator
  
  小野賢二郎
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Showa University
アミロイドβ毒性阻害を標的としたアルツハイマー病発症予防健康食品成分の探索Ongoing
- Principal Investigator
  
  辻まゆみ
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Showa University
Study on transmission of sporadic cerebral amyloid angiopathy
- Principal Investigator
  
  YAMADA Masahito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
The elucidation of Abeta aggregation mechanism using high-speed atomic force microscopyPrincipal Investigator
- Principal Investigator
  
  Ono Kenjiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
  Kanazawa University
A study on propagation of cerebral b-amyloidosis with protein contained in foods and cosmetics
- Principal Investigator
  
  Hamaguchi Tsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Study on possible transmission of Alzheimer's disease with medical procedures and food
- Principal Investigator
  
  YAMADA Masahito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Analysis of the effect of human living specimen on amyloid β-protein oligomerizationPrincipal Investigator
- Principal Investigator
  
  ONO Kenjiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
生体分子及び有機化合物のαーシヌクレイン凝集に及ぼす影響の解析Principal Investigator
- Principal Investigator
  
  小野賢二郎
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University

All 2017 2016 2015 2014 2013 2012 2011 2010 2007 2006 Other

All Journal Article Presentation Patent

[Journal Article] Cerebral amyloid angiopathy-related microbleeds and CSF biomarkers in Alzheimer's disease2017
- Author(s)
  Noguchi-Shinohara M, Komatsu J, Samuraki M, Matsunari I, Ikeda T, Sakai K, Hamaguchi T, Ono K, Nakamura H, Yamada M.
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 55 Pages: 905-913
- DOI
  10.3233/jad-160651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-26860234, KAKENHI-PROJECT-15K15336
[Journal Article] Tocotrienol-rich fraction modulates amyloid pathology and improves cognitive function in AβPP/PS1 mice2017
- Author(s)
  Ibrahim NF, Yanagisawa D, Durania LW, Hamezaha HS, HDamanhuri HD, Wan Ngahb WZ, Tsuji M, Kiuchi Y, Ono K, Tooyama I
- Journal Title
  
  Journal of Alzheimer’s Disease
  
  Volume: 55 Pages: 51-61
- DOI
  10.3233/jad-160685
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290022, KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-15K16321
[Journal Article] Coexistence of transthyretin- and Aβ-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis2017
- Author(s)
  Sakai K, Asakawa M, Takahashi R, Ishida C, Nakamura R, Hamaguchi T, Ono K, Iwasa K, Yamada M
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 381 Pages: 144-146
- DOI
  10.1016/j.jns.2017.08.3240
- NAID
  120006375106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15336
[Journal Article] Granuloma formation in a patient with GNE myopathy: A case report.2017
- Author(s)
  Nakamura K, Hamaguchi T, Sakai K, Noto D, Ono K, Hayashi Y, Nishino I, Yamada M.
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 27 Pages: 183-184
- DOI
  10.1016/j.nmd.2016.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] MELASによる脳卒中様発作2017
- Author(s)
  村上秀友, 小野賢二郎
- Journal Title
  
  Brain and Nerve
  
  Volume: 69 Pages: 111-117
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Aβ凝集に焦点をあてたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎, 山田正仁
- Journal Title
  
  老年期認知症研究会誌
  
  Volume: 21 Pages: 20-22
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Efficacy of levetiracetam in primary hemifacial spasm.2016
- Author(s)
  Kuroda T, Saito Y, Fujita K, Yano S, Ishigaki S, Kato H, Murakami H, Ono K.
- Journal Title
  
  J Clin Neurosci
  
  Volume: 34 Pages: 213-215
- DOI
  10.1016/j.jocn.2016.05.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] fMRIからみた統辞処理の神経機構2016
- Author(s)
  金野竜太, 小野賢二郎
- Journal Title
  
  高次脳機能研究
  
  Volume: 36 Pages: 255-262
- NAID
  130006894317
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] High-speed atomic force microscopy reveals structural dynamics of amyloid β1-42 aggregates.2016
- Author(s)
  Watanabe-Nakayama T*, Ono K*, Itami M, Takahashi R, Teplow DB, Yamada M. *Equally contributed.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 113 Pages: 5835-5840
- DOI
  10.1073/pnas.1524807113
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] α-シヌクレイン凝集とレビー小体型認知症の根本治療薬開発2016
- Author(s)
  高橋良一, 小野賢二郎, 山田正仁
- Journal Title
  
  認知症の最新医療
  
  Volume: 6 Pages: 128-133
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] オリゴマー仮説に基づいたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Journal Title
  
  神経化学
  
  Volume: 55 Pages: 42-51
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Parkinson病および関連疾患の治療の進歩2016
- Author(s)
  村上秀友, 小野賢二郎, 河村満
- Journal Title
  
  神経治療薬
  
  Volume: 4 Pages: 518-521
- NAID
  130006638881
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] 抗パーキンソン病薬・抗てんかん薬によって誘発される認知症・認知障害2016
- Author(s)
  村上秀友, 小野賢二郎
- Journal Title
  
  医薬ジャーナル
  
  Volume: 52 Pages: 2489-2491
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers2016
- Author(s)
  Umeda T., Ono K., Sakai A., Yamashita M., Mizuguchi M, Klein W.L., Yamada M., Mori H., Tomiyama T
- Journal Title
  
  Brain
  
  Volume: 139 Pages: 1568-1586
- DOI
  10.1093/brain/aww042
- NAID
  120006371274
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290018, KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-16K19057
[Journal Article] アルツハイマー型認知症および認知症の疫学研究2016
- Author(s)
  石垣征一郎, 小野賢二郎
- Journal Title
  
  Pharma Medica
  
  Volume: 34 Pages: 9-12
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] パーキンソン病の認知障害のバイオマーカー2016
- Author(s)
  小野賢二郎, 山田正仁
- Journal Title
  
  Dementia Japan
  
  Volume: 30 Pages: 223-228
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] 高齢者てんかんと認知症の関連2016
- Author(s)
  石垣征一郎, 小野賢二郎
- Journal Title
  
  認知症の最新医療
  
  Volume: 6 Pages: 189-190
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Dopaminergic drug management in Parkinson’s disease: gait and language function show correlation during treatment.2016
- Author(s)
  Murakami H., Momma Y., Nohara T., Mori Y., Futamura A., Sugita T., Ishigaki S., Katoh H., Kezuka M., Ono K., Miller M.W., Kawamura M.
- Journal Title
  
  J Parkinsons Dis.
  
  Volume: 6 Pages: 209-217
- DOI
  10.3233/jpd-150702
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461266, KAKENHI-PLANNED-25119006
[Journal Article] Inclusion body myositis with granuloma formation in muscle tissue.2015
- Author(s)
  Sakai K, Ikeda Y, Ishida C, Matsumoto Y, Ono K, Iwasa K, Yamada M.
- Journal Title
  
  Neuromuscular Disorders
  
  Volume: 25 Pages: 706-712
- DOI
  10.1016/j.nmd.2015.06.460
- NAID
  120005661916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Role of intestinal microbiota in the generation of polyphenol derived phenolic acid mediated attenuation of Alzheimer’s disease β-amyloid oligomerization.2015
- Author(s)
  Wang D., Ho L., Faith J., Ono K., Janle E.M., Lachcik P.J., Cooper B.R., Jannasch A.H., D’Arcy B.R., Williams B.A., Ferruzzi M.G., Levine S., Zhao W., Dubner L., Pasinetti G.M.
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 59 Pages: 1025-1040
- DOI
  10.1002/mnfr.201400544
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Phenolic compounds prevent the oligomerization of α-synuclein and reduce synaptic toxicity.2015
- Author(s)
  Takahashi R., Ono K., Takamura Y., Mizuguchi M., Ikeda T., Nishijo H., Yamada M.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 134 Pages: 943-955
- DOI
  10.1111/jnc.13180
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Pharmacokinetics, Safety and Tolerability of Melissa officinalis Extract which Contained Rosmarinic Acid in Healthy Individuals: A Randomized Controlled Trial.2015
- Author(s)
  Noguchi-Shinohara M., Ono K., Hamaguchi T., Iwasa K., Nagai T., Kobayashi S., Nakamura H., Yamada M.
- Journal Title
  
  PLoS One.
  
  Volume: 10
- DOI
  10.1371/journal.pone.0126422
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-15H02894, KAKENHI-PROJECT-15H04783, KAKENHI-PROJECT-25670295
[Journal Article] Exacerbation of myasthenia gravis by intravenous peramivir.2015
- Author(s)
  Hayashi K., Iwasa K., Morinaga A., Ono K., Yamada M.
- Journal Title
  
  Muscle & Nerve
  
  Volume: 51 Pages: 935-936
- DOI
  10.1002/mus.24594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Cerebral amyloid angiopathy-related microbleeds correlate with glucose metabolism and brain volume in Alzheimer's disease.2015
- Author(s)
  Samuraki M., Matsunari I., Yoshita M., Shima K., Noguchi-Shinohara M., Hamaguchi T., Ono K., Yamada M.
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 48 Pages: 517-528
- DOI
  10.3233/jad-150274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Efficacy of diflunisal on autonomic dysfunction of late-onset familial amyloid polyneuropathy (TTR Val30Met) in a Japanese endemic area2014
- Author(s)
  Takahashi R, Ono K, Shibata S, Nakamura K, Komatsu J, Ikeda Y, Ikeda T, Samuraki M, Sakai K, Iwasa K, Kayano D, Yamada M
- Journal Title
  
  J Neurol Sci
  
  Volume: 345 Pages: 231-235
- DOI
  10.1016/j.jns.2014.07.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Myasthenia gravis: predictive factors associated with the synchronized elevation of anti-acetylcholine receptor antibody titer in Kanazawa, Japan2014
- Author(s)
  Iwasa K, Yoshikawa H, Samuraki M, Shinohara M, Hamaguchi T, Ono K, Nakamura H, Yamada M
- Journal Title
  
  J Neuroimmunol.
  
  Volume: 267(2014) Pages: 97-101
- DOI
  10.1016/j.jneuroim.2013.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390160, KAKENHI-PROJECT-24591253, KAKENHI-PROJECT-25670295, KAKENHI-PROJECT-26461266
[Journal Article] Exogenous amyloidogenic proteins function as seeds in amyloid β-protein aggregation2014
- Author(s)
  Ono K, Takahashi R, Ikeda T, Mizuguchi M, Hamaguchi T, Yamada M
- Journal Title
  
  Biochim Biophys Acta (Molecular Basis of Disease)
  
  Volume: 1842 Pages: 646-653
- DOI
  10.1016/j.bbadis.2014.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Molecular topology as novel strategy for discovery of drugs with Aβ lowering and anti-aggregation dual activities for Alzheimer's disease2014
- Author(s)
  Wang J, Land D, Ono K, Galvez J, Zhao W, Vempati P, Steele JW, Cheng A, Yamada M, Levine S, Mazzola P, Pasinetti GM
- Journal Title
  
  PLoS One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0092750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Neurolymphomatosis exhibiting repeated exacerbation and remission in both the peripheral and central nervous systems.2014
- Author(s)
  Akagi A, Ono K, Hamaguchi T, Samuraki M, Nakada M, Shima Y, Oohata T, Yamada M.
- Journal Title
  
  J Neurol Sci
  
  Volume: 345 Pages: 267-268
- DOI
  10.1016/j.jns.2014.07.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Green coffee as a novel agent for Alzheimer’s disease prevention by attenuating diabetes2014
- Author(s)
  Varghese M, Ho L, Wang J, Zhao W, Levine S, Ono K, Mannino S, Pasinetti GM
- Journal Title
  
  Translational Neuroscience
  
  Volume: 5 Pages: 111-116
- DOI
  10.2478/s13380-014-0213-y
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Cocoa extracts reduce oligomerization of amyloid-β: implications for cognitive improvement in Alzheimer's disease2014
- Author(s)
  Wang J, Varghese M, Ono K, Yamada M, Levine S, Tzavaras N, Gong B, Hurst WJ, Blitzer RD, Pasinetti GM
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 41 Pages: 643-650
- DOI
  10.3233/jad-132231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Effects of the neurotrophic agent T-817MA on oligomeric amyloid β-induced deficits in long-term potentiation in the hippocampal CA1 subfield2014
- Author(s)
  Takamura Y*, Ono K*, Matsumoto J, Yamada M, Nishijo H ＊Equally contributed
- Journal Title
  
  Neurobiol Aging
  
  Volume: 35 Pages: 532-536
- DOI
  10.1016/j.neurobiolaging.2013.08.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266
[Journal Article] Anti-amyloidogenic effects of soybean isoflavones in vitro: fluorescence spectroscopy demonstrating direct binding to Aβ monomers, oligomers and fibrils.2012
- Author(s)
  Hirohata M, Ono K, Takasaki JI, Takahashi R, Ikeda T, Morinaga A, Yamada M
- Journal Title
  
  Biochim. Biophys. Acta (Molecular Basis of Disease)
  
  Volume: 1822 Pages: 1316-1324
- DOI
  10.1016/j.bbadis.2012.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Phenolic compounds prevent amyloid β-Protein oligomerization and synaptic dysfunction by site specific binding.2012
- Author(s)
  Ono K, Li L, Takamura Y, Yoshiike Y, Zhu L, Han F, Mao X, Ikeda T, Takasaki JI, Nishijo H, Takashima A, Teplow DB, Zagorski MG, Yamada M
- Journal Title
  
  J Biol Chem
  
  Volume: (印刷中) Pages: 14631-14643
- DOI
  10.1074/jbc.m111.325456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390242, KAKENHI-PROJECT-22240051, KAKENHI-PROJECT-22790815
[Journal Article] Coagulation and fibrinolysis abnormalities in familial amyloid polyneuropathy2012
- Author(s)
  Takahashi R, Ono K, Ikeda T, Akagi A, Noto D, Nozaki I, Sakai K, Asakura H, Iwasa K, Yamada M
- Journal Title
  
  Amyloid
  
  Volume: 19 Pages: 129-132
- DOI
  10.3109/13506129.2012.691918
- NAID
  120004754690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Vitamin A and Alzheimer's disease2012
- Author(s)
  Ono. K. Yamada. M
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: (in press)
- NAID
  10031147981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Posterior cingulate atrophy and metabolic decline in early stage Alzheimer's disease.2012
- Author(s)
  Shima K, Samuraki M, Chen WP, Yanase D, Noguchi-Shinohara M, Takeda N, Ono K, Yoshita M, Miyazaki Y, Matsuda H, Yamada M, Matsunari I
- Journal Title
  
  Neurobiol Aging
  
  Volume: 33 Pages: 2006-2017
- DOI
  10.1016/j.neurobiolaging.2011.07.009
- NAID
  10031007048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment2012
- Author(s)
  Wang. J, Ferruzzi. MG, Ho. L,Blount. J, Janle. EM, Gong. B,Pan. Y, Gowda. N, Raftery. D,Arrieta-Cruz. I, Sharma. V, Cooper. B, Lobo. J, Simon. J, Zhang. C, Cheng. A, Qian. X, Ono. K, Teplow. DB, Pavlides. C, Dixon. R, Pasinetti. G
- Journal Title
  
  J Neurosci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Effect of melatonin on α-synuclein self-assembly and cytotoxicity2012
- Author(s)
  Ono K, Mochizuki H, Ikeda T, Nihira T, Takasaki J, Teplow DB, Yamada M
- Journal Title
  
  Neurobiol Aging
  
  Volume: 33 Pages: 2172-2185
- DOI
  10.1016/j.neurobiolaging.2011.10.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Vitamin A and Alzheimer’s disease2012
- Author(s)
  Ono K, Yamada M
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 12 Pages: 180-188
- DOI
  10.1111/j.1447-0594.2011.00786.x
- NAID
  10031147981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cross-seeding effects of amyloid β-protein and α-synuclein2012
- Author(s)
  Ono K,*Takahashi R,*Ikeda T, Yamada M
- Journal Title
  
  J. Neurochem
  
  Volume: 122 Pages: 883-890
- DOI
  10.1111/j.1471-4159.2012.07847.x
- NAID
  120005285928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659170, KAKENHI-PROJECT-22790815
[Journal Article] Parkinson's disease showing progressive conduction aphasia2012
- Author(s)
  Sakai K, Ono K, Harada H, Shima K, Notoya M, Yamada M
- Journal Title
  
  Neurol. Sci
  
  Volume: 33 Pages: 399-402
- DOI
  10.1007/s10072-011-0751-9
- NAID
  120005285929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Nicotinamide riboside restores cognition through an up-regulation of PGC-1α regulated BACE1 degradation and mitochondrial gene expression in Alzheimer's mouse models2012
- Author(s)
  Gong B, Pan Y, Vempati P, Zhao W, Knable L, Ho L, Wang J, Sastre M, Ono K, Pasinetti GM
- Journal Title
  
  Neurobiol. Aging
  
  Volume: (in press)
- URL
  http://dx.doi.org/10.1016/j.neurobiolaging.2012.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment2012
- Author(s)
  Wang J, Ferruzzi MG, Ho L, Blount J, Janle EM, Gong B, Pan Y, Gowda N, Raftery D, Arrieta-Cruz I, Sharma V, Cooper B, Lobo J, Simon J, Zhang C, Cheng A, Qian X, Ono K, Teplow DB, Pavlides C, Dixon R, Pasinetti G
- Journal Title
  
  J Neurosci
  
  Volume: 11 Pages: 5144-5150
- DOI
  10.1523/jneurosci.6437-11.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cerebrospinal fluid from patients with multiple system atrophy promotes in vitro α-synuclein fibril formation2011
- Author(s)
  Hirohata. M, Ono. K, Morinaga. A, Ikeda. T, Yamada. M
- Journal Title
  
  Neurosci Lett
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Effects of sex hormones on Alzheimer's disease-associated β-amyloid oligomer formation in vitro2011
- Author(s)
  Morinaga A, Ono K, Takasaki J, Ikeda T, Hirohata M, Yamada M
- Journal Title
  
  Exp Neurol
  
  Volume: 228 Pages: 298-302
- DOI
  10.1016/j.expneurol.2011.01.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cervical flexion myelopathy in a patient showing apparent long tract signs: a severe form of Hirayama disease2011
- Author(s)
  Sakai K, Ono K, Okamoto Y, Murakami H and Yamada M
- Journal Title
  
  Joint Bone Spine
  
  Volume: 78 Pages: 316-318
- DOI
  10.1016/j.jbspin.2010.12.008
- NAID
  120002772028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Effect of an age-mismatched and sex-mismatched normal database on the diagnostic performance of ^<18>F-FDG PET for Alzheimer's disease : the Ishikawa Brain Imaging Study2011
- Author(s)
  Chen WP, Samuraki M, Shima K, Yanase D, Nozomi, Takeda N, Miyazaki Y, Ono K, Yoshita M, Nishimura S, Yamada M, Matsunari I
- Journal Title
  
  Nucl Med Commun
  
  Volume: 32 Pages: 1128-1133
- DOI
  10.1097/mnm.0b013e32834b43c2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Findings of Familial Dementia with a Tau R406W Mutation2011
- Author(s)
  Komatsu. J, Ono. K,Yanase. D, Samuraki. M, Shima. K, Kuwano. R, Matsunari. I, Yamada. M
- Journal Title
  
  Acta Neurol Berg
  
  Volume: 111 Pages: 374-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Carvedilol as a potential novel agent for the treatment of Alzheimer's disease2011
- Author(s)
  Wang J, Ono K, Dickstein D, Arrieta-Cruz I, Zhao W, Qian X, Lamparello A, Ferruzzi MG, Pavlides C, Ho L, Hof P, Teplow DB, Pasinetti GM
- Journal Title
  
  Neurobiol. Aging
  
  Volume: 32
- DOI
  10.1016/j.neurobiolaging.2010.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Fisher syndrome associated with immune thrombocytopenic purpura2011
- Author(s)
  Furukawa Y, Iwasa K, Ono K and Yamada M
- Journal Title
  
  Intern. Med
  
  Volume: 50 Pages: 631-633
- NAID
  130000649898
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21422692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Low-n oligomers as therapeutic targets of Alzeheimer's disease2011
- Author(s)
  Ono K, Yamada M
- Journal Title
  
  J Neurochem
  
  Volume: 117 Pages: 19-28
- DOI
  10.1111/j.1471-4159.2011.07187.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Familial Parkinson disease mutations influence α-synuclein assembly2011
- Author(s)
  Ono K, Takasaki J, Ikeda T, Yamada M
- Journal Title
  
  Neurobiol Dis
  
  Volume: 43 Pages: 715-724
- DOI
  10.1016/j.nbd.2011.05.025
- NAID
  120003308572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Imaging Findings of Familial Dementia with a Tau R406W Mutation2011
- Author(s)
  Komatsu J, Ono K, Yanase D, Samuraki M, Shima K, Kuwano R, Matsunari I, Yamada M
- Journal Title
  
  Acta Neurol. Berg
  
  Volume: 111 Pages: 374-375
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22368988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cervical flexion myelopathy in a patient showing apparent long tract signs : a severe form of Hirayama disease2011
- Author(s)
  Sakai. K, Ono. K,Okamoto. Y, Murakami. H, Yamada. M
- Journal Title
  
  Joint Bone Spine
  
  Volume: 78 Pages: 316-318
- NAID
  120002772028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Vitamin A has antioligomerization effects on amyloid-β in vitro2011
- Author(s)
  Takasaki J-I, Ono K, Yoshiike Y, Hirohata M, Ikeda T, Morinaga A, Takashima A, Yamada M
- Journal Title
  
  J. Alzheimers. Dis
  
  Volume: 27 Pages: 271-280
- DOI
  10.3233/jad-2011-110455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390242, KAKENHI-PROJECT-22790815
[Journal Article] Cerebrospinal fluid from patients with multiple system atrophy promotes in vitro α-synuclein fibril formation2011
- Author(s)
  Hirohata M, Ono K, Morinaga A, Ikeda T, Yamada M
- Journal Title
  
  Neurosci. Lett
  
  Volume: 491 Pages: 48-52
- DOI
  10.1016/j.neulet.2011.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] A comparison of the diagnosticsensitivity of MRI, CBF-SPECT, FDG-PET, and cerebrospinal fluid biomarkers for detecting Alzheimer's disease in a memory clinic2010
- Author(s)
  Morinaga A, Ono K, Ikeda T, Ikeda Y, Shima K, Shinohara M,Samuraki M,Yanase D, Yoshita M, Mastunari I, Yamada M
- Journal Title
  
  Dement. Geriatr. Cogn. Disord
  
  Volume: 30 Pages: 285-292
- DOI
  10.1159/000320265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cerebrospinal fluid of Alzheimer patients promotes amyloid β-Protein oligomerization2010
- Author(s)
  Ikeda T, Ono K, Elashoff D, Margaret C, Noguchi-Shinohara M, Yoshita M, Teplow DB, Yamada M
- Journal Title
  
  J. Alzheimers. Dis
  
  Volume: 21 Pages: 81-86
- DOI
  10.3233/jad-2010-100075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease2010
- Author(s)
  Wang. J, Santa-Maria. I, Ho. L, Ksiezak-Reding. H, Ono. K, Teplow. DB, Pasinetti. GM
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 22 Pages: 653-661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Curcumin and Alzheimer's disease2010
- Author(s)
  Hamaguchi T, Ono K, Yamada M.
- Journal Title
  
  CNS Neurosci. Ther
  
  Volume: 16 Pages: 285-297
- DOI
  10.1111/j.1755-5949.2010.00147.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cerebrospinal fluid of Alzheimer patients promotes amyloid β-Protein oligomerization2010
- Author(s)
  Ikeda. T, Ono. K, Elashoff. D, Condron. MM, Noguchi-Shinohara. M, Yoshita. M, Teplow. DB, Yamada. M
- Journal Title
  
  J Alzheimcrs Dis
  
  Volume: 21 Pages: 81-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Ono K, Condron MM, Teplow DB2010
- Author(s)
  Ono K, Condron MM, Teplow DB
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 23186-23197
- DOI
  10.1074/jbc.m109.086496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Effects of the English (H6R) and Tottori (D7N) familial Alzheimer disease mutations on amyloid β-protein assembly and toxicity2010
- Author(s)
  Ono. K, Condron. MM, Teplow. DB
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 23186-23197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] A comparison of the diagnostic sensitivity of MRI, CBF-SPECT, FDG-PET, and cerebrospinal fluid biomarkers for detecting Alzheimer's disease in a memory clinic2010
- Author(s)
  Morinaga. A, Ono. K, Ikeda. T, Ikeda. Y, Shima. K, Shinohara. M, Samuraki. M, Yanase. D, Yoshita. M, Mastunari. I, Yamada. M
- Journal Title
  
  Dement Geriatr Cogn Disord
  
  Volume: 30 Pages: 285-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Sakai K, Ono K, Ohta K, Yamada M2010
- Author(s)
  Sakai K, Ono K, Ohta K, Yamada M
- Journal Title
  
  Intern. Med
  
  Volume: 49 Pages: 1261-1262
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20558962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Curcumin and Alzheimer's disease2010
- Author(s)
  Hamaguchi. T, Ono. K, Yamada. M
- Journal Title
  
  CNS Neurosci Ther
  
  Volume: 16 Pages: 285-297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease2010
- Author(s)
  Wang J, Santa-Maria I, Ho L, Ksiezak-Reding H, Ono K, Teplow DB, Pasinetti GM
- Journal Title
  
  J. Alzheimers. Dis
  
  Volume: 22 Pages: 653-661
- DOI
  10.3233/jad-2010-101074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790815
[Journal Article] Cerebrospinal fluid of Alzheimer's disease and dementia with Lewy bodies patients enhances alpha-synuclein fibril formation. in vitro.2007
- Author(s)
  Kenjiro Ono, Noguchi-Shinohara M, Mitsuhiro Yoshita, Hironobu Naiki, Masahito Yamada
- Journal Title
  
  Exp Neurol 203
  
  Pages: 579-583
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Vitamin A potently destabilizes preformed alpha-synuclein fibrils in vitro : Implications for Lewy body diseases.2007
- Author(s)
  Kenjiro Ono, Masahito Yamada
- Journal Title
  
  Neurobiol Dis 25
  
  Pages: 446-454
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Alpha-lipoic acid exhibits anti-amyloidogenicity for beta-amyloid fibrils in vitro.2006
- Author(s)
  Kenjiro Ono, Mie Hirohata, Masahito Yamada
- Journal Title
  
  Biochem Biophys Res Commun 341
  
  Pages: 1046-1052
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro.2006
- Author(s)
  Kenjiro Ono, Masahito Yamada
- Journal Title
  
  J Neurochem 97
  
  Pages: 105-115
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Anti-Parkinsonian agents have anti-amyloidogenic activity for Alzheimer's beta-amyloid fibrils in vitro.2006
- Author(s)
  Kenjiro Ono, Kazuhiro Hasegawa, Hironobu Naiki, Masahito Yamada
- Journal Title
  
  Neurochem Int 48
  
  Pages: 275-285
- Data Source
  KAKENHI-PROJECT-18790589
[Journal Article] Anti-fibrillogenic and fibril-destabilizing activities of anti-Parkinsonian agents for alpha-synuclein fibrils in vitro.
- Author(s)
  Kenjiro Ono, Mie Hirohata, Masahito Yamada
- Journal Title
  
  J Neurosci Res (印刷中)
- Data Source
  KAKENHI-PROJECT-18790589
[Patent] レビー小体病治療薬及びレビー小体病予防薬2006
- Inventor(s)
  山田正仁, 小野賢二郎
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Filing Date
  2006-01-16
- Data Source
  KAKENHI-PROJECT-18790589
[Presentation] 食品関連因子による認知症予防・治療法の開発2016
- Author(s)
  山田正仁、篠原もえ子、小野賢二郎、浜口毅
- Organizer
  第58回日本老年医学会学術集会
- Place of Presentation
  石川県立音楽堂/ANAクラウンプラザホテル/金沢アートホール（金沢）
- Year and Date
  2016-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病における微小出血と脳脊髄液バイオマーカーとの関連2016
- Author(s)
  篠原もえ子、小松潤史、佐村木美晴、松成一朗、池田篤平、坂井健二、濱田毅、小野賢二郎、山田正仁
- Organizer
  第7回日本脳血管・認知症学会学術大会
- Place of Presentation
  金沢都ホテル（金沢）
- Year and Date
  2016-08-06
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 進行性非流暢性/失文法性失語の脳血流部位に関する研究2016
- Author(s)
  金野竜太、黒川信二、大湾喜行、二村明憲、四郎丸あずさ、笠井英世、黒田岳志、矢野怜、石垣征一郎、村上秀友、小野賢二郎
- Organizer
  第21回日本神経精神医学会
- Place of Presentation
  くまもと県民交流館パレア（熊本）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アミロイド仮説に基づいたアルツハイマー型認知症予防・治療薬開発2016
- Author(s)
  小野　賢二郎
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー型認知症の診断と治療2016
- Author(s)
  小野賢二郎
- Organizer
  第146回日本神経学会東海北陸地方会
- Place of Presentation
  石川県地場産業振興センター（金沢）
- Year and Date
  2016-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 外因性アミロイド蛋白のアミロイドβ蛋白凝集へのクロス・シーディング効果2016
- Author(s)
  小野賢二郎、高橋良一、池田篤平、水口峰之、浜口毅、山田正仁
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京）
- Year and Date
  2016-08-19
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病におけるCAA関連微小出血と脳脊髄液バイオマーカーとの関連2016
- Author(s)
  篠原もえ子、小松潤史、佐村木美晴、松成一朗、池田篤平、坂井健二、濱口毅、小野賢二郎、山田正仁
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] オリゴマー仮説に基づいたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-07-20
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Exogenous amyloidogenic proteins function as seeds in Aβ aggregation2016
- Author(s)
  Ono K, Takahashi R, Ikeda T, Mizuguchi M, Hamaguchi T, Yamada M
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego convention center（アメリカ）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病の病態研究の最前線：オリゴマーの実体とは何か？2016
- Author(s)
  小野賢二郎
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 123I-Ioflupane SPECT predicts the efficacy of selegiline monotherapyfor motor symptoms in drug-naive Parkinson's disease2016
- Author(s)
  Murakami H, Ishigaki S, Katoh H, Ono K
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego convention center（アメリカ）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病における脳アミロイドアンギオパチー関連微小出血と脳糖代謝・灰白質容量との関係2016
- Author(s)
  佐村木美晴、松成一朗、吉田光宏、島啓介、篠原もえ子、濱口毅、小野賢二郎、山田正仁
- Organizer
  第7回日本脳血管・認知症学会学術大会
- Place of Presentation
  金沢都ホテル（金沢）
- Year and Date
  2016-08-06
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Parkinson 病初発例の運動症状に対するドパミン作動薬の効果と DAT スキャン所見との関連2016
- Author(s)
  村上秀友、石垣征一郎、加藤大貴、小野賢二郎
- Organizer
  第34回日本神経治療学会総会
- Place of Presentation
  米子コンベンションセンター/米子市文化ホール（米子）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 2015年度日本神経学会賞受賞講演：フェノール化合物に焦点をあてたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] オリゴマー仮説に基づいたアルツハイマー型認知症治療薬の研究2016
- Author(s)
  小野賢二郎
- Organizer
  第7回日本脳血管・認知症学会学術大会
- Place of Presentation
  金沢都ホテル（金沢）
- Year and Date
  2016-08-06
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Aβ凝集過程と阻害薬開発2016
- Author(s)
  小野賢二郎
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京）
- Year and Date
  2016-08-19
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] オリゴマオパチーとしてのアルツハイマー病2016
- Author(s)
  小野賢二郎
- Organizer
  第21回日本神経感染症学会総会学術大会
- Place of Presentation
  金沢東急ホテル（金沢）
- Year and Date
  2016-10-21
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 関東地区推薦講演：Aβ凝集に焦点をあてたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第30回老年期認知症研究会
- Place of Presentation
  コクヨホール（東京）
- Year and Date
  2016-07-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー病における脳アミロイドアンギオパチー関連微小出血と脳脊髄液バイオマーカーとの関連2016
- Author(s)
  佐村木美晴、松成一朗、吉田光宏、島啓介、篠原もえ子、濱田毅、小野賢二郎、山田正仁
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京）
- Year and Date
  2016-08-19
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 非薬物学的アプローチからアルツハイマー型認知症を考える2016
- Author(s)
  小野賢二郎
- Organizer
  第11回日本リハビリテーション医学会専門医会学術集会
- Place of Presentation
  金沢市文化ホール（金沢）
- Year and Date
  2016-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー型認知症の診断と治療2016
- Author(s)
  小野賢二郎
- Organizer
  第55回全国自治体病院学会
- Place of Presentation
  富山県民会館/富山第一ホテル（富山）
- Year and Date
  2016-10-20
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アルツハイマー型認知症の診断と治療2016
- Author(s)
  小野賢二郎
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 早期凝集体に焦点を当てたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Exogenous amyloid proteins function as seeds in amyloid β-protein aggregation2016
- Author(s)
  小野賢二郎、高橋良一、池田篤平、水口峰之、浜口毅、山田正仁
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター/神戸ポートピアホテル（神戸）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 高速原子力間顕微鏡を用いたAβ42凝集過程の観察2016
- Author(s)
  小野賢二郎、中山隆宏、伊丹将大、高橋良一、David Teplow、山田正仁
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 2016年度日本神経化学会優秀賞受賞講演：オリゴマー仮説に基づいたアルツハイマー病の予防・治療薬の開発2016
- Author(s)
  小野賢二郎
- Organizer
  第59回日本神経化学会大会・第38回日本生物学的精神医学会合同年会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2016-09-08
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 現在のAD治療と予防・治療薬の開発2015
- Author(s)
  小野　賢二郎
- Organizer
  第39回日本高次脳機能障害学会学術総会
- Place of Presentation
  ベルサール渋谷ファースト（東京）
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 病態に基づいたアルツハイマー型認知症の予防・治療薬開発2015
- Author(s)
  小野　賢二郎
- Organizer
  第25回日本医療薬学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 有機化合物に焦点をあてたαシヌクレイン凝集抑制薬の開発2015
- Author(s)
  小野　賢二郎、高橋　良一，山田　正仁
- Organizer
  第56回日本神経学会学術集会
- Place of Presentation
  朱鷺メッセ(新潟)
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 外因性アミロイド蛋白のアミロイドβ蛋白凝集へのクロス・シーディング効果2015
- Author(s)
  小野　賢二郎、高橋良一、池田篤平、水口峰之、浜口毅、山田正仁
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーション青森（青森）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Positioning of early aggregates of Aβ in its aggregation process2015
- Author(s)
  小野　賢二郎、中山　隆宏、山田　正仁
- Organizer
  第56回日本神経学会学術集会
- Place of Presentation
  朱鷺メッセ(新潟)
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Effects of Antiparkinsonian Agents on β-amyloid and α-synuclein Oligomer Formarion in vitro.2015
- Author(s)
  Ono K, Takasaki J-I, Takahashi R, Ikeda T, Yamada M.
- Organizer
  Neuroscience 2015
- Place of Presentation
  Chicago
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 第10回十全医学賞受賞記念講演　フェノール化合物に焦点をあてたアルツハイマー病の予防・治療薬開発2014
- Author(s)
  小野賢二郎
- Organizer
  平成26年度金沢大学十全医学会学術集会
- Place of Presentation
  金沢大学十全講堂（金沢）
- Year and Date
  2014-06-24
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] アミロイドβ蛋白とα-シヌクレイン蛋白のクロス・シーディング効果2014
- Author(s)
  小野賢二郎、高橋良一、池田篤平、山田正仁
- Organizer
  第2回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京）
- Year and Date
  2014-08-22
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Vitamin A, Phenolic Compounds, and Alzheimer's Disease2013
- Author(s)
  Ono K
- Organizer
  Conference on Health Aging in Asia
- Place of Presentation
  Grand Copthorne Waterfront (Singapore)
- Invited
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Low order-oligomers as therapeutic targets of Alzeheimer's disease2012
- Author(s)
  Ono K
- Organizer
  Neuroscience Seminar in University of British Columbia
- Place of Presentation
  University of British Columbia (Canada)
- Year and Date
  2012-07-17
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 家族性アミロイドポリニューロパチーの凝固・線溶異常2012
- Author(s)
  高橋良一,小野賢二郎,池田篤平,赤木明生,能登大介,野崎一朗,坂井健二,朝倉英策,岩佐和夫,山田正仁
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Anti-Amyloidogenic Effects of lsoflavones In Vitro: Fluorescence Spectroscopy Demonstrating Direct Interractions Between Isoflavones and Aβs2012
- Author(s)
  Hirohata M, Ono K, Takasaki J, Yamada M
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2012
- Place of Presentation
  Vancouver Convention Center (Canada)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] フェノール化合物は特異的結合によってAβオリゴマー形成及びシナプス毒性を抑制する2012
- Author(s)
  小野賢二郎
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば国際会議場（茨城県）
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] NSAIDsはβアミロイド蛋白オリゴマー形成抑制作用およびシーディング抑制作用を有する2012
- Author(s)
  廣畑美枝,小野賢二郎,高崎純一,森永章義,池田篤平,山田正仁
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 有機化合物に焦点をあてたアルツハイマー病の予防・治療薬の開発2012
- Author(s)
  小野賢二郎
- Organizer
  第54回日本老年医学会学術集会　ノバルティス老化および老年医学研究基金受賞講演
- Place of Presentation
  東京国際フォーラム（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Vitamin A inhibits Aβ oligomerization in vitro2012
- Author(s)
  Ono K
- Organizer
  第35回日本神経科学大会　Neuroscience 2012
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] フェノール化合物は特異的結合によってAβオリゴマー形成及びシナプス毒性を抑制する2012
- Author(s)
  小野賢二郎,Lei Li,高村雄策,吉池裕二,池田篤平,西条寿夫,高島明彦, David B Teplow, Michael G Zagorski,山田正仁
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば国際会議場(茨城県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Vitamin A has anti-oligomerization effects on amyloid-β in vitro2012
- Author(s)
  Ono K
- Organizer
  Alzheimer’s Association International Conference on Alzheimer’s Disease 2012
- Place of Presentation
  Vancouver Convention Center (Canada)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 有機化合物に焦点をあてたアルツハイマー病の予防・治療薬の開発2012
- Author(s)
  小野賢二郎
- Organizer
  第54回日本老年医学会学術集会ノバルティス老化および老年医学研究基金受賞講演
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Vitamin A has anti-oligomerization effects on amyloid-β in vitro2012
- Author(s)
  Ono K, Takasaki J, Yoshiike Y, Hirohata M, Ikeda T, Morinaga A, Takashima A, Yamada M
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2012
- Place of Presentation
  Vancouver Convention Center (Canada)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] ビタミンAによるAβオリゴマー形成抑制効果2012
- Author(s)
  小野賢二郎,高崎純一,吉池裕二,廣畑美枝,池田篤平,森永章義,高島明彦,山田正仁
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] ビタミンAによるAβオリゴマー形成抑制効果2012
- Author(s)
  小野賢二郎
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] イソフラボンのβアミロイド蛋白モノマー・オリゴマー・線維への作用の検討2012
- Author(s)
  廣畑美枝,小野賢二郎,高崎純一,高橋良一,池田篤平,森永章義,山田正仁
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば国際会議場(茨城県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Vitamin A inhibits Aβ oligomerization in vitro2012
- Author(s)
  Ono K, Takasaki J, Yoshiike Y, Hirohata M, Ikeda T, Morinaga A, Takashima A, Yamada M
- Organizer
  第35回日本神経科学大会 Neuroscience 2012
- Place of Presentation
  名古屋国際会議場(愛知県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Effect of melatonin on α-synuclein self-assembly and cytotoxicity2011
- Author(s)
  Ono. K, Mochizuki. H, Ikeda. T, Nihira. T, Takasaki. J, Teplow. DB, Yamada. M
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2011
- Place of Presentation
  Expo in Porte de Versailles (France)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English (H6R) 及び Tottori (D7N) 型変異がアミロイドβ蛋白の凝集および細胞毒性に与える影響2011
- Author(s)
  小野賢二郎,David B Teplow,山田正仁
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English(H6R)及びTottori型(D7N)変異アミロイドβ蛋白の凝集および細胞毒性2011
- Author(s)
  小野賢二郎、Teplow. DB、山田正仁
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English(H6R)及びTottori(D7N)変異アミロイドβ蛋白の凝集および細胞毒性2011
- Author(s)
  小野賢二郎、Teplow. DB、山田正仁
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アルツハイマー病βアミロイド蛋白凝集機構解明から予防・治療薬開発へ2011
- Author(s)
  小野賢二郎
- Organizer
  第54回日本神経化学大会ミニランチョンセミナー
- Place of Presentation
  瑠璃光(石川県)(招待講演)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Low-n oligomers as therapeutic targets of Alzeheimer's disease2011
- Author(s)
  Ono K
- Organizer
  Neuroscience Seminar in University of Groningen
- Place of Presentation
  University of Groningen(Netherlands)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English(H6R)及びTottori(D7N)型変異がアミロイドβ蛋白の凝集および細胞毒性に与える影響2011
- Author(s)
  小野賢二郎、Teplow. DB、山田正仁
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Low-n oligomers as therapeutic targets of Alzeheimer's disease2011
- Author(s)
  Ono. K
- Organizer
  Neuroscience Seminar in University of Groningen
- Place of Presentation
  University of Groningen (Netherlands)(招待講演)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Effect of melatonin on α-synuclein self-assembly and cytotoxicity2011
- Author(s)
  Ono K, Mochizuki H, Ikeda T, Nihira T, Takasaki J, Teplow DB, Yamada M
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2011
- Place of Presentation
  Expo in Porte de Versailles(France)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English (H6R) 及び Tottori 型(D7N)変異アミロイドβ蛋白の凝集および細胞毒性2011
- Author(s)
  小野賢二郎,David B Teplow,山田正仁
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  タワーホール船堀(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アルツハイマー病βアミロイド蛋白凝集機構解明から予防・治療薬開発へ2011
- Author(s)
  小野賢二郎
- Organizer
  第54回日本神経化学大会ミニランチョンセミナー
- Place of Presentation
  瑠璃光(石川県)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] English (H6R) 及び Tottori (D7N) 変異アミロイドβ蛋白の凝集および細胞毒性2011
- Author(s)
  小野賢二郎,David B Teplow,山田正仁
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 神経変性疾患(特にアルツハイマー病、パーキンソン病)の予防・治療薬開発2010
- Author(s)
  小野賢二郎
- Organizer
  平成22年度昭和大学医学部同窓会学術講演会
- Place of Presentation
  昭和大学医学部(東京)
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アミロイドβ蛋白オリゴマーの構造-毒性相関2010
- Author(s)
  小野賢二郎, Margaret M Condron, David B Teplow, 山田正仁
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Aβ凝集機構解明から予防・治療薬開発へ2010
- Author(s)
  小野賢二郎
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  ウインクあいち(愛知県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アミロイドβ蛋白オリゴマーの構造及び毒性相関の解析2010
- Author(s)
  小野賢二郎, David B Teplow, Margaret M Condron, 山田正仁
- Organizer
  Neuro2010
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Structure-neurotoxicity analysis of amyloid β-protein oligomers.2010
- Author(s)
  Ono K, Teplow DB, Condron. MM
- Organizer
  International Conference on Alzheimer's Disease 2010
- Place of Presentation
  Hawaii Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Structure-neurotoxicity relationships of amyloid β-protein oligomers2010
- Author(s)
  小野賢二郎,David B Teplow,山田正仁
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  ウインクあいち(愛知県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 有機化合物に焦点を当てたアルツハイマー病の予防・治療薬の開発2010
- Author(s)
  小野賢二郎
- Organizer
  京都大学農学研究科大学院特別講義
- Place of Presentation
  京都大学(京都)
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Structure-neurotoxicity relationships of amyloid β-protein oligomers2010
- Author(s)
  小野賢二郎, David B Teplow, 山田正仁
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  ウインクあいち(名古屋)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Grape derived polyphenols attenuate tau neuropathology in the tmht mouse model of Alzheimer's disease2010
- Author(s)
  Wang J, Santa-Maria I, Ho L, Ksiezak-Reding H, Ono K, Teplow DB, Pasinetti GM
- Organizer
  Neuroscience Nanosymposium 2010
- Place of Presentation
  San Diego Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] アミロイドβ蛋白オリゴマーの構造及び毒性相関の解析2010
- Author(s)
  小野賢二郎,David B Teplow,Margaret M Condron,山田正仁
- Organizer
  第33回日本神経科学大会 Neuro2010
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 神経変性疾患(特にアルツハイマー病、パーキンソン病)の予防・治療薬開発2010
- Author(s)
  小野賢二郎
- Organizer
  平成22年度昭和大学医学部同窓会学術講演会
- Place of Presentation
  昭和大学医学部(東京都)
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Grape derived polyphenols attenuate tau neuropathology in the tmht mouse model of Alzheimer's disease2010
- Author(s)
  Wang. J, Santa-Maria. I, Ho. L, Ksiezak-Reding. H, Ono. K, Teplow. DB, Pasinetti. GM
- Organizer
  Neuroscience Nanosymposium 2010
- Place of Presentation
  コンベンションセンター(米国・サンディエゴ)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Structure-neurotoxicity analysis of amyloid β-protein oligomers2010
- Author(s)
  Ono. K, Teplow. DB, Condron. MM
- Organizer
  International Conference on Alzheimer's Disease 2010
- Place of Presentation
  コンベンションセンター(米国・ホノルル)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Aβ凝集機構解明から予防・治療薬開発へ2010
- Author(s)
  小野賢二郎
- Organizer
  第29回日本認知症学会学術集会シンポジウム5 認知症の阻止を狙った治療薬開発研究
- Place of Presentation
  ウインクあいち(名古屋)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 小野賢二郎,Margaret M Condron,David B Teplow,山田正仁2010
- Author(s)
  小野賢二郎,Margaret M Condron,David B Teplow,山田正仁
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] Low order-oligomers as therapeutic targets of Alzeheimer’s disease
- Author(s)
  Ono. K
- Organizer
  Neuroscience Seminar in University of British Columbia
- Place of Presentation
  University of British Columbia (Canada)
- Invited
- Data Source
  KAKENHI-PROJECT-22790815
[Presentation] 病態に基づいたAlzheimer 病の予防・治療薬の開発
- Author(s)
  小野賢二郎、山田正仁
- Organizer
  第32回日本神経治療学会総会
- Place of Presentation
  東京ドームホテル（東京）
- Year and Date
  2014-11-20 – 2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] 抗パーキンソン病薬のアミロイドβ蛋白及びαシヌクレイン蛋白のオリゴマー形成抑制
- Author(s)
  小野賢二郎、高崎純一、高橋良一、池田篤平、山田正仁
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  パシフィッコ横浜（横浜）
- Year and Date
  2014-11-29 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] バイオマーカーの視点からPDの認知障害を考える
- Author(s)
  小野賢二郎、山田正仁
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  パシフィッコ横浜（横浜）
- Year and Date
  2014-11-29 – 2014-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Cross-seeding effects of amyloid β-protein and α-synuclein
- Author(s)
  Ono K, Takahashi R, Ikeda T, Yamada M.
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Cross-seeding effects of amyloid β-protein and α-synuclein
- Author(s)
  Ono K, Takahashi R, Ikeda T, Yamada M
- Organizer
  第37回日本神経科学大会　Neuroscience 2014
- Place of Presentation
  パシフィッコ横浜（横浜）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26461266
[Presentation] Cross-seeding effects of amyloid β-protein and α-synuclein
- Author(s)
  Ono K, Takahashi R, Ikeda T, Yamada M
- Organizer
  Alzheimer’s Association International Conference on Alzheimer’s Disease 2014
- Place of Presentation
  コペンハーゲン（デンマーク）
- Year and Date
  2014-07-12 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-26461266

1. YAMADA Masahito (80191336)

# of Collaborated Projects: 4 results

# of Collaborated Products: 43 results
2. Hamaguchi Tsuyoshi (70452109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 辻まゆみ (40155544)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAKAYAMA Takahiro (00532821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. SAKAI Kenji (00572306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. YOSHIKAWA Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. UMEDA Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 西条寿夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 遠山育夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 柳沢大治郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 中村裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 小林彰子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 森啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 富山貴美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 河村満

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ono kenjiro 小野 賢二郎

小野 賢二郎 オノ ケンジロウ

Ono Kenjiro 小野 賢二郎

ONO Kenjiro 小野 賢二郎

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膜障害に焦点を当てた高分子Aβオリゴマーの毒性機序に関する検討Principal InvestigatorOngoing

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アミロイドβ毒性阻害を標的としたアルツハイマー病発症予防健康食品成分の探索Ongoing

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Study on transmission of sporadic cerebral amyloid angiopathy

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The elucidation of Abeta aggregation mechanism using high-speed atomic force microscopyPrincipal Investigator

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A study on propagation of cerebral b-amyloidosis with protein contained in foods and cosmetics

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Study on possible transmission of Alzheimer's disease with medical procedures and food

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Analysis of the effect of human living specimen on amyloid β-protein oligomerizationPrincipal Investigator

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生体分子及び有機化合物のαーシヌクレイン凝集に及ぼす影響の解析Principal Investigator

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[Journal Article] Cerebral amyloid angiopathy-related microbleeds and CSF biomarkers in Alzheimer's disease2017

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[Journal Article] Tocotrienol-rich fraction modulates amyloid pathology and improves cognitive function in AβPP/PS1 mice2017

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[Journal Article] Coexistence of transthyretin- and Aβ-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis2017

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NAID

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[Journal Article] Granuloma formation in a patient with GNE myopathy: A case report.2017

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[Journal Article] MELASによる脳卒中様発作2017

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ono kenjiro 小野賢二郎

小野賢二郎オノケンジロウ

Ono Kenjiro 小野賢二郎

ONO Kenjiro 小野賢二郎