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ITO TOSHIHIRO  伊藤 利洋

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ITO Toshihiro  伊藤 利洋

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Researcher Number 00595712
Other IDs
Affiliation (Current) 2025: 奈良県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2025: 奈良県立医科大学, 医学部, 教授
2014 – 2023: 奈良県立医科大学, 医学部, 教授
2015: 岡山大学, 大学院医歯薬学総合研究科, 講師
2012 – 2013: 岡山大学, 医歯(薬)学総合研究科, 講師
2012: 岡山大学, 大学院・医歯薬学総合研究科, 講師
2011: 岡山大学, 医歯(薬)学総合研究科, 助教
Review Section/Research Field
Principal Investigator
Experimental pathology / Basic Section 49020:Human pathology-related / Respiratory organ internal medicine
Except Principal Investigator
Basic Section 53030:Respiratory medicine-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Complex systems / Basic Section 54020:Connective tissue disease and allergy-related / Respiratory organ internal medicine / Laboratory medicine / Experimental pathology
Keywords
Principal Investigator
エピジェネティクス / マクロファージ / 気道上皮細胞 / インフルエンザウィルス / 遺伝学 / 感染症 / エピジェネ手ィクス / 内科 / 細菌 / ウィルス … More / エピゲネティクス / エピジェネチティクス / 免疫学 / 肺炎球菌 / インフルエンザウイルス / 慢性炎症 / 呼吸器感染症 / 慢性呼吸器疾患 / ヒストンメチル化 / 免疫病理学 / 細菌性肺炎 … More
Except Principal Investigator
肺線維症 / HLA-F / 再生医療 / 肺胞上皮 / 肺気腫 / 腸内細菌叢 / 柿タンニン / HLA class Ib / 抗体療法 / 免疫療法 / 特発性肺線維症 / 炎症性腸疾患 / 形態測定 / 肥満予防 / 肥満 / 脂質蓄積 / antibody / tumor / SCID-beige / SCID / PDX / immunotherapy / 再生 / 肺胞破壊 / 慢性呼吸不全 / 形態学 / 胸部CT / 胸部画像 / 動物実験 / COPD / 肺胞再生 / 間葉系幹細胞 / フリーラジカル / 呼吸不全 / 酸化ストレス / 形態評価 / 画像解析 / 慢性閉塞性肺疾患 / シングルセルトランスクリプトーム / 情報工学 / モデル化 / 病理学 / 遺伝子 / 免疫学 / 細胞間相互作用 / RNA-seq / single-cell / ネットワーク解析 / single-cell RNA-seq / 新規マーカー / オーダーメード治療 / 間葉系幹細胞療法 / オーダーメイド治療 / PTPRR / 間葉系幹細胞治療 / 炎症性腸疾患改善 / DSS誘導性大腸炎 / 潰瘍性大腸炎 / ヒストン修飾 / SETDB2 / B細胞 / 自己抗体 / ヒストン修飾酵素 / インターフェロン / 腫瘍免疫 / 悪性腫瘍 / 病理組織標本 / 腫瘍マーカー / 制御性T細胞 / 合併肺癌 / 特発性間質性肺炎合併肺癌 / 肺癌 / 肺線維症合併肺癌 / 制御性T細胞 / 悪性度 / 低分化癌 / ホルマリン標本 / 大腸癌 / 診断 / 腫瘍 / 免疫染色 / ウイルス感染 / 急性肺傷害 / 発がん / シグナル伝達 / 炎症・自然免疫 / 炎症とがん / シグナル伝達・抑制 / 炎症 Less
  • Research Projects

    (16 results)
  • Research Products

    (139 results)
  • Co-Researchers

    (41 People)
  •  組織空間的プロファイリング技術による肺線維症の病態解明と新規病理診断法の創出Principal Investigator

    • Principal Investigator
      伊藤 利洋
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Nara Medical University
  •  Quantitative Morphometric Measurements of Alveolar Regeneration in Emphysema among Mouse Model and Human lung.

    • Principal Investigator
      室 繁郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nara Medical University
  •  Development of a novel cancer immunotherapy targeting the immune checkpoint molecule, HLA-F.

    • Principal Investigator
      Ouji-Sageshima Noriko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Nara Medical University
  •  Relationship between persimmon tannin-related changes in gut microbiota and obesity prevention

    • Principal Investigator
      Matsumura Yoko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Kio University
  •  An attempt to establish a method to evaluate alveolar repair mechanisms comparing human emphysema CT images and mouse experiments

    • Principal Investigator
      Muro Shigeo
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nara Medical University
  •  Search for effective new markers for clinical application of mesenchymal stem cell therapy in patients with pulmonary fibrosis

    • Principal Investigator
      Kumamoto Makiko
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nara Medical University
  •  Development of new tumor diagnosis marker and new cancer immunotherapy targeting HLA-F

    • Principal Investigator
      Ouji-sageshima Noriko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Nara Medical University
  •  Role of histon methyltransferase SETDB2 on the autoantibody production

    • Principal Investigator
      Kitabatake Masahiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Nara Medical University
  •  Elucidation of the pathological improvement mechanism of inflammatory bowel disease with persimmon tannin

    • Principal Investigator
      Yoko Matsumura
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Kio University
  •  Search for new therapeutic strategies targeting regulatory T cells for lung cancer with pulmonary fibrosis

    • Principal Investigator
      Shigeto Hontsu
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nara Medical University
  •  Inflammation cellular society in pulmonary fibrosis

    • Principal Investigator
      Matsushima Kouji
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo University of Science
      The University of Tokyo
  •  Investigation of molecular basis of exacerbation in chronic respiratory disease caused by respiratory infectionPrincipal Investigator

    • Principal Investigator
      Ito Toshihiro
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nara Medical University
  •  The development of new pathologic diagnosis system using HLA-F expression on tumor

    • Principal Investigator
      Ouji-Sageshima Noriko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nara Medical University
  •  Regulatory mechanism of inflammation and inflammation-related cancer by regulating Ras-Raf-ERK/MAPK

    • Principal Investigator
      MATSUKAWA AKIHIRO
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Okayama University
  •  Investigation of new therapeutic target against influenza virus infectionPrincipal Investigator

    • Principal Investigator
      ITO TOSHIHIRO
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Nara Medical University
      Okayama University
  •  The epigeneticanalysis of secondary bacterial pneumonia following influenza virus infectionPrincipal Investigator

    • Principal Investigator
      ITO Toshihiro
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Okayama University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book Patent

  • [Book] BIO Clinica2019

    • Author(s)
      伊藤 利洋
    • Total Pages
      5
    • Publisher
      北隆館
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Book] NEUROINFECION(神経感染症)2014

    • Author(s)
      松川昭博、伊藤利洋
    • Publisher
      医学中央雑誌
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Book] 病理と臨床2014

    • Author(s)
      板倉淳哉, 伏見聡一郎, 荻野哲也, 伊藤利洋, 小田晋輔, 河原明奈, 萩谷英大, 桑原宏子, 松川昭博
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Book] 消化器と免疫2014

    • Author(s)
      高橋索真、平岡佐規子、伏見聡一郎、伊藤利洋、板倉淳哉、木村亮二郎、揚旭、篠倉美理、中川裕貴、住居優一、竹井大介、井口俊博、半井明日香、森藤由記、秋田光洋、原田馨太、岡田裕之、松川昭博、山本和秀
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Journal Article] CD8+ T-cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by shifts in clonal dominance2024

    • Author(s)
      H, Aoki., M, Kitabatake., H, Abe., P, Xu., M, Tsunoda., S, Shichino., A, Hara., N, Ouji- Sageshima., C, Motozono., T, Ito., K, Matsushima., and S, Ueha
    • Journal Title

      Cell reports

      Volume: 43 Issue: 3 Pages: 113887-113902

    • DOI

      10.1016/j.celrep.2024.113887

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KK0277, KAKENHI-PROJECT-21K07246, KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-23K24139
  • [Journal Article] Angiopoietin-like 4 is a critical regulator of fibroblasts during pulmonary fibrosis development2023

    • Author(s)
      Shoichiro Saito, Masahiro Kitabatake, Noriko Ouji-Sageshima, Tatsuro Ogawa, Akihisa Oda, Tomoko Nishimura, Tatsuki Nishioka, Satoki Fushimi, Atsushi Hara, Shigeyuki Shichino, Makiko Kumamoto, Shigeto Hontsu, Takeshi Kawaguchi, Satoshi Ueha, Noriyoshi Sawabata, Shigeo Muro, Kouji Matsushima, Toshihiro Ito
    • Journal Title

      American Journal of Respiratory Cell and Molecular Biology

      Volume: - Issue: 3 Pages: 328-339

    • DOI

      10.1165/rcmb.2022-0304oc

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08661, KAKENHI-PROJECT-23K07632, KAKENHI-PROJECT-21K07825, KAKENHI-PROJECT-21K08162, KAKENHI-PLANNED-22H05064
  • [Journal Article] A Disintegrin and Metalloproteinase with Thrombospondin Motifs 4 Regulates Pulmonary Vascular Hyperpermeability through Destruction of Glycocalyx in Acute Respiratory Distress Syndrome2023

    • Author(s)
      Konda Makiko、Kitabatake Masahiro、Ouji-Sageshima Noriko、Tonomura Rei、Furukawa Ryutaro、Sonobe Shota、Terada-Ikeda Chiyoko、Takeda Maiko、Kawaguchi Masahiko、Ito Toshihiro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 22 Pages: 16230-16230

    • DOI

      10.3390/ijms242216230

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09310, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162
  • [Journal Article] Antiviral Effect of Candies Containing Persimmon-Derived Tannin against SARS-CoV-2 Delta Strain2023

    • Author(s)
      Furukawa Ryutaro、Kitabatake Masahiro、Ouji-Sageshima Noriko、Tomita Dai、Kumamoto Makiko、Suzuki Yuki、Nakano Akiyo、Nakano Ryuichi、Matsumura Yoko、Kayano Shin-ichi、Yano Hisakazu、Tamaki Shinji、Ito Toshihiro
    • Journal Title

      Viruses

      Volume: 15 Issue: 8 Pages: 1636-1636

    • DOI

      10.3390/v15081636

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K10948, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K11587
  • [Journal Article] Dietary Phenolic Compounds: Their Health Benefits and Association with the Gut Microbiota2023

    • Author(s)
      Matsumura Yoko、Kitabatake Masahiro、Kayano Shin-ichi、Ito Toshihiro
    • Journal Title

      Antioxidants

      Volume: 12 Issue: 4 Pages: 880-880

    • DOI

      10.3390/antiox12040880

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11587, KAKENHI-PROJECT-23K10948
  • [Journal Article] The spleen is the major site for the development and expansion of inhibitor producing-cells in hemophilia A mice upon FVIII infusion developing high-titer inhibitor2023

    • Author(s)
      Akihisa Oda, Shoko Furukawa, Masahiro Kitabatake, Noriko Ouji-Sageshima, Shota Sonobe, Kaoru Horiuchi, Yuto Nakajima, Kenichi Ogiwara, Ryo Goitsuka, Midori Shima, Toshihiro Ito, Keiji Nogami
    • Journal Title

      Thrombosis research

      Volume: 3848 Pages: 00077-4

    • DOI

      10.1016/j.thromres.2023.03.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07825, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21H02372
  • [Journal Article] Transition of Antibody Titers after SARS-CoV-2 mRNA Vaccination in Japanese Healthcare Workers2023

    • Author(s)
      Kitabatake Masahiro、Ouji-Sageshima Noriko、Sonobe Shota、Furukawa Ryutaro、Konda Makiko、Hara Atsushi、Aoki Hiroyasu、Suzuki Yuki、Imakita Natsuko、Nakano Akiyo、Fujita Yukio、Shichino Shigeyuki、Nakano Ryuichi、Ueha Satoshi、Kasahara Kei、Muro Shigeo、Yano Hisakazu、Matsushima Kouji、Ito Toshihiro
    • Journal Title

      Jpn J Infect Dis

      Volume: 76 Issue: 1 Pages: 72-76

    • DOI

      10.7883/yoken.JJID.2022.041

    • ISSN
      1344-6304, 1884-2836
    • Year and Date
      2023-01-31
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162, KAKENHI-PROJECT-20H03474, KAKENHI-PROJECT-20K08573, KAKENHI-WRAPUP-22H04906, KAKENHI-PROJECT-23K07632
  • [Journal Article] The balance of comprehensive coagulation and fibrinolytic potential is disrupted in patients with moderate to severe COVID-192022

    • Author(s)
      Onishi Tomoko、Kawaguchi Ryuji、Nishio Tomohisa、Nogami Keiji、et al
    • Journal Title

      International Journal of Hematology

      Volume: 2 Issue: 6 Pages: 1-12

    • DOI

      10.1007/s12185-022-03308-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10488, KAKENHI-PROJECT-22K16330, KAKENHI-PROJECT-20K08573
  • [Journal Article] TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq.2022

    • Author(s)
      Shichino S, Ueha S, Hashimoto S, Ogawa T, Aoki H, Wu B, Chen CY, Kitabatake M, Ouji-Sageshima N, Sawabata N, Kawaguchi T, Okayama T, Sugihara E, Hontsu S, Ito T, Iwata Y, Wada T, Ikeo K, Sato T, Matsushima K.
    • Journal Title

      Communications Biology

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Journal Article] Human iPS cell-derived cartilaginous tissue spatially and functionally replaces nucleus pulposus2022

    • Author(s)
      Kamatani Takashi、Hagizawa Hiroki、Yarimitsu Seido、Morioka Miho、Koyamatsu Saeko、Sugimoto Michihiko、Kodama Joe、Yamane Junko、Ishiguro Hiroyuki、Shichino Shigeyuki、Abe Kuniya、Fujibuchi Wataru、Fujie Hiromichi、Kaito Takashi、Tsumaki Noriyuki
    • Journal Title

      Biomaterials

      Volume: 284 Pages: 121491-121491

    • DOI

      10.1016/j.biomaterials.2022.121491

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19312, KAKENHI-PROJECT-18H02424, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-21K19242, KAKENHI-PROJECT-20K06453
  • [Journal Article] Pure Solid Pattern of Non-Small Cell Lung Cancer and Clustered Circulating Tumor Cells2022

    • Author(s)
      Sawabata Noriyoshi、Kawaguchi Takeshi、Watanabe Takashi、Yohikawa Daiki、Ouji-Sageshima Noriko、Ito Toshihiro
    • Journal Title

      Cancers

      Volume: 14 Issue: 18 Pages: 4514-4514

    • DOI

      10.3390/cancers14184514

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21H03021
  • [Journal Article] Lipopolysaccharide from Yoshino cedar trees (Cryptomeria japonica) induces high levels of human macrophage polarization2022

    • Author(s)
      Noriko Ouji-Sageshima, Masahiro Kitabatake, Satoki Fushimi, Satoshi Suzuki, Yuzu Fukui, Ryutaro Furukawa and Toshihiro Ito
    • Journal Title

      Journal of Wood Science

      Volume: 68 Pages: 63-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07246
  • [Journal Article] Transient Depletion of CD4 + Cells Induces Remodeling of the TCR Repertoire in Gastrointestinal Cancer.2021

    • Author(s)
      Aoki H, Ueha S, Shichino S, Ogiwara H, Shitara K, Shimomura M, Suzuki T, Nakatsura T, Yamashita M, Kitano S, Kuroda S, Wakabayashi M, Kurachi M, Ito S, Doi T, Matsushima K.
    • Journal Title

      Cancer Immunol Res.

      Volume: - Issue: 6 Pages: 624-636

    • DOI

      10.1158/2326-6066.cir-20-0989

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-17K07207, KAKENHI-PROJECT-19K07476, KAKENHI-PROJECT-20H03474
  • [Journal Article] Persimmon-derived tannin has antiviral effects and reduces the severity of infection and transmission of SARS-CoV-2 in a Syrian hamster model2021

    • Author(s)
      Furukawa Ryutaro、Kitabatake Masahiro、Ouji-Sageshima Noriko、Suzuki Yuki、Nakano Akiyo、Matsumura Yoko、Nakano Ryuichi、Kasahara Kei、Kubo Kaoru、Kayano Shin-ichi、Yano Hisakazu、Ito Toshihiro
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 23695-23695

    • DOI

      10.1038/s41598-021-03149-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K11638, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162
  • [Journal Article] Transition of antibody titers after the SARS-CoV-2 mRNA vaccine in Japanese healthcare workers2021

    • Author(s)
      Kitabatake Masahiro、Ouji-Sageshima Noriko、Sonobe Shota、Furukawa Ryutaro、Konda Makiko、Hara Atsushi、Aoki Hiroyasu、Suzuki Yuki、Imakita Natsuko、Nakano Akiyo、Fujita Yukio、Shichino Shigeyuki、Nakano Ryuichi、Ueha Satoshi、Kasahara Kei、Muro Shigeo、Yano Hisakazu、Matsushima Kouji、Ito Toshihiro
    • Journal Title

      medRxiv

      Volume: - Pages: 1-9

    • DOI

      10.1101/2021.12.28.21268435

    • Open Access
    • Data Source
      KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-20K17469
  • [Journal Article] Vein-first Lobectomy for Lung Cancer Assessed According to the Status of Clustered Circulating Tumour Cells2021

    • Author(s)
      SAWABATA NORIYOSHI、NAKANE SHIGERU、YOSHIKAWA DAIKI、WATANABE TAKASHI、KAWAGUCHI TAKESHI、OUJI-SAGESHIMA NORIKO、KUSHIBE KEIJI、ITO TOSHIHIRO
    • Journal Title

      Cancer Diagnosis & Prognosis

      Volume: 1 Issue: 5 Pages: 443-450

    • DOI

      10.21873/cdp.10059

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07246
  • [Journal Article] Human Adipose-Derived Mesenchymal Stem Cells Ameliorate Elastase-Induced Emphysema in Mice by Mesenchymal-Epithelial Transition.2021

    • Author(s)
      Fujioka N, Kitabatake M, Ouji-Sageshima N, Ibaraki T, Kumamoto M, Fujita Y, Hontsu S, Yamauchi M, Yoshikawa M, Muro S, Ito T.
    • Journal Title

      Int J Chron Obstruct Pulmon Dis

      Volume: 8 Pages: 2783-2793

    • DOI

      10.2147/copd.s324952

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17642, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162
  • [Journal Article] Persimmon-derived tannin ameliorates the pathogenesis of ulcerative colitis in a murine model through inhibition of the inflammatory response and alteration of microbiota2021

    • Author(s)
      Kitabatake Masahiro、Matsumura Yoko、Ouji-Sageshima Noriko、Nishioka Tatsuki、Hara Atsushi、Kayano Shin-ichi、Ito Toshihiro
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 7286-7286

    • DOI

      10.1038/s41598-021-86608-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K11638, KAKENHI-PROJECT-18K11148, KAKENHI-PROJECT-21K07246
  • [Journal Article] Human Adipose-Derived Mesenchymal Stem Cells Ameliorate Elastase-Induced Emphysema in Mice by Mesenchymal-Epithelial Transition2021

    • Author(s)
      Fujioka N, Kitabatake M, Ouji-Sageshima N, Ibataki T, Kumamoto M, Fujita Y, Hontsu S, Yamauchi M, Yoshikawa M, Muro S, Ito T.
    • Journal Title

      Int J Chron Obstruct Pulmon Dis

      Volume: 16 Pages: 2783-2793

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08573
  • [Journal Article] Respiratory Syncytial Virus Infection Exacerbates Pneumococcal Pneumonia via Gas6/Axl-mediated Macrophage Polarization2020

    • Author(s)
      Shibata T, Makino A, Ogata R, Nakamura S, Ito T, Nagata K, Terauchi Y, Oishi T, Fujieda M, Takahashi Y, Ato M.
    • Journal Title

      J Clin Invest .

      Volume: 6 Issue: 6 Pages: 3021-3037

    • DOI

      10.1172/jci125505

    • NAID

      120007017546

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07183, KAKENHI-PROJECT-16H05310, KAKENHI-PROJECT-20K08258
  • [Journal Article] First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors2019

    • Author(s)
      Shitara K、Ueha S、Shichino S、Aoki H、Ogiwara H、Nakatsura T、Suzuki T、Shimomura M、Yoshikawa T、Shoda K、Kitano S、Yamashita M、Nakayama T、Sato A、Kuroda Sakiko、Wakabayashi Masashi、Nomura Shogo、Yokochi Shoji、Ito Satoru、Matsushima Kouji、Doi Toshihiko
    • Journal Title

      Journal for ImmunoTherapy of Cancer

      Volume: 7 Issue: 1 Pages: 195-195

    • DOI

      10.1186/s40425-019-0677-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-19K16620
  • [Journal Article] Responses of perivascular macrophages to circulating lipopolysaccharides in the subfornical organ with special reference to endotoxin tolerance.2019

    • Author(s)
      Morita-Takemura S, Nakahara K, Hasegawa-Ishii S, Isonishi A, Tatsumi K, Okuda H, Tanaka T, Kitabatake M, Ito T, Wanaka A.
    • Journal Title

      J Neuroinflammation

      Volume: 16 Issue: 1 Pages: 39-51

    • DOI

      10.1186/s12974-019-1431-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07395, KAKENHI-PROJECT-18K08412, KAKENHI-PROJECT-16H05310, KAKENHI-PROJECT-16K18980, KAKENHI-PROJECT-18K06836
  • [Journal Article] Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis.2019

    • Author(s)
      Shichino S, Ueha S, Hashimoto S, Otsuji M, Abe J, Tsukui T, Deshimaru S, Nakajima T, Kosugi-Kanaya M, Shand FH, Inagaki Y, Shimano H, Matsushima K.
    • Journal Title

      JCI Insight.

      Volume: 4(1) Issue: 1 Pages: 122163-122163

    • DOI

      10.1172/jci.insight.122163

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K19546, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392
  • [Journal Article] Abrogated Caveolin-1 expression via histone modification enzyme Setdb2 regulates brain edema in a mouse model of influenza-associated encephalopathy.2019

    • Author(s)
      Imakita N, Kitabatake M, Ouji-Sageshima N, Hara A, Morita-Takemura S, Kasahara K, Matsukawa A, Wanaka A, Mikasa K, Ito T.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 284-284

    • DOI

      10.1038/s41598-018-36489-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08412, KAKENHI-PROJECT-16H05310, KAKENHI-PROJECT-16K15258, KAKENHI-PROJECT-18K06836
  • [Journal Article] Young adult patients with squamous cell carcinoma of the tongue strongly express p16 without human papillomavirus infection2019

    • Author(s)
      Tachibana Tomoyasu、Orita Yorihisa、Gion Yuka、Miki Kentaro、Ikegami Kana、Marunaka Hidenori、Makino Takuma、Akagi Yusuke、Akisada Naoki、Tsumura Munechika、Ito Toshihiro、Yoshino Tadashi、Nishizaki Kazunori、Sato Yasuharu
    • Journal Title

      Acta Oto-Laryngologica

      Volume: 139 Issue: 1 Pages: 80-84

    • DOI

      10.1080/00016489.2018.1541506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05310, KAKENHI-PROJECT-17K11385, KAKENHI-PROJECT-19K18731
  • [Journal Article] Osteogenesis of osteogenic matrix cell sheets preserved in culture medium in a rat model2018

    • Author(s)
      Kira Tsutomu、Akahane Manabu、Ouji-Sageshima Noriko、Shimizu Takamasa、Onishi Tadanobu、Omokawa Shohei、Ito Toshihiro、Tanaka Yasuhito
    • Journal Title

      Cell Transplantation

      Volume: 27 Issue: 8 Pages: 1281-1288

    • DOI

      10.1177/0963689718786233

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Journal Article] Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues.2017

    • Author(s)
      Hashimoto S, Tabuchi Y, Yurino H, Hirohashi Y, Deshimaru S, Asano T, Mariya T, Oshima K, Takamura Y, Ukita Y, Ametani A, Kondo N, Monma N, Takeda T, Misu S, Okayama T, Ikeo K, Saito T, Kaneko S, Suzuki Y, Hattori M, Matsushima K, et al.
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 14225-14225

    • DOI

      10.1038/s41598-017-14676-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19546, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H01540
  • [Journal Article] Spred2-deficiecy Protects Mice from Polymicrobial Septic Peritonitis by Enhancing Inflammation and Bacterial Clearance2017

    • Author(s)
      Itakura Junya、Sato Miwa、Ito Toshihiro、Mino Megumi、Fushimi Soichiro、Takahashi Sakuma、Yoshimura Teizo、Matsukawa Akihiro
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 12833-12833

    • DOI

      10.1038/s41598-017-13204-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15258, KAKENHI-PROJECT-16H05310
  • [Journal Article] Silencing of Carbohydrate Sulfotransferase 15 Hinders Murine Pulmonary Fibrosis Development2017

    • Author(s)
      Yoshiro Kai, Koichi Tomoda, Hiroyuki Yoneyama, Masahiro Kitabatake, Atsuhiro Nakamura, Toshihiro Ito, Masanori Yoshikawa, and Hiroshi Kimura.
    • Journal Title

      Molecular Therapy - Nucleic Acids

      Volume: 6 Pages: 163-172

    • DOI

      10.1016/j.omtn.2016.12.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09532, KAKENHI-PROJECT-16K09551, KAKENHI-PROJECT-16H05310
  • [Journal Article] SIV targeting of CXCR3+CD4+ T cells in secondary lymphoid organs associates with robust CXCL10 expression in monocyte/macrophage subsets.2017

    • Author(s)
      Fujino, M., H. Sato, T. Okamura, A. Uda, S. Takeda, N. Ahmed, S. Shichino, T. Shiino, Y. Saito, S. Watanabe, C. Sugimoto, M. Kuroda, M. Ato, Y. Nagai, S. Izumo, K. Matsushima, M. Miyazawa, A. Ansari, F. Villinger, and K. Mori
    • Journal Title

      Journal of Virology

      Volume: 印刷中 Issue: 13

    • DOI

      10.1128/jvi.00439-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01268, KAKENHI-PROJECT-16H05199, KAKENHI-PROJECT-15K10043, KAKENHI-PROJECT-17K19546, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H05203
  • [Journal Article] The HIV co-receptor CCR5 regulates osteoclast function.2017

    • Author(s)
      Lee JW, Hoshino A, Inoue K, Saitou T, Uehara S, Kobayashi Y, Ueha S, Matsushima K, Yamaguchi A, Imai Y, Iimura T.
    • Journal Title

      Nat Commun

      Volume: 8 Issue: 1 Pages: 2226-2226

    • DOI

      10.1038/s41467-017-02368-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-17K19546, KAKENHI-PROJECT-17K19728, KAKENHI-PROJECT-16K20412, KAKENHI-PROJECT-26293392, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-15H04961, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-15F15113, KAKENHI-PROJECT-16K15791, KAKENHI-PROJECT-16K18578
  • [Journal Article] Persimmon-derived tannin has bacteriostatic and anti-inflammatory activity in a murine model of Mycobacterium avium complex (MAC) disease2017

    • Author(s)
      Yoko Matsumura, Masahiro Kitabatake, Noriko Ouji-Sageshima, Satsuki Yasui, Naoko Mochida, Ryuichi Nakano, Kei Kasahara, Koichi Tomoda, Hisakazu Yano, Shin-ichi Kayano, Toshihiro Ito
    • Journal Title

      PLoS One

      Volume: 12 Issue: 8 Pages: e0183489-e0183489

    • DOI

      10.1371/journal.pone.0183489

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05310, KAKENHI-PROJECT-15K09532
  • [Journal Article] Combination of anti-CD4 antibody treatment and donor lymphocyte infusion ameliorates graft-versus-host disease while preserving graft-versus-tumor effects in murine allogeneic hematopoietic stem cell transplantation.2017

    • Author(s)
      Ueha S, Yokochi S, Ishiwata Y, Kosugi-Kanaya M, Shono Y, Shibayama S, Ito S, Matsushima K.
    • Journal Title

      Cancer Sci

      Volume: 108 Issue: 10 Pages: 1967-1973

    • DOI

      10.1111/cas.13346

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K19546, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-15F15113
  • [Journal Article] Establishment of optimized ELISA system specific for HLA-G in body fluids.2016

    • Author(s)
      Ouji-Sageshima N, Geraghty DE, Ishitani A, Hatake K, Ito T
    • Journal Title

      HLA

      Volume: 88 Issue: 6 Pages: 293-299

    • DOI

      10.1111/tan.12919

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461957, KAKENHI-PROJECT-15K08650
  • [Journal Article] sHLA-G and sHLA-I levels in follicular fluid are not associated with successful implantation.2016

    • Author(s)
      Ouji-Sageshima N, Yuui K, Nakanishi M, Takeda N, Odawara Y, Yamashita M, Iwayama H, Awai K, Hashimoto H, Geraghty DE, Ishitani A, Hatake K, Ito T
    • Journal Title

      J Reprod Immunol.

      Volume: 113 Pages: 16-21

    • DOI

      10.1016/j.jri.2015.10.001

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08650, KAKENHI-PROJECT-25461957
  • [Journal Article] Sprouty-Related Ena Vasodilator-Stimulated Phosphoprotein Homology 1-Domain Containing Protein-2 Critically Regulates Influenza A Virus Induced Pneumonia2016

    • Author(s)
      Toshihiro Ito, Junya Itakura, Sakuma Takahashi, Miwa Sato, Megumi Mino, Soichiro Fushimi, Masao Yamada, Tuneo Morishima, Steven L. Kunkel, Akihiro Matsukawa
    • Journal Title

      Critical Care Medicine

      Volume: 44 Issue: 7 Pages: e530-e543

    • DOI

      10.1097/ccm.0000000000001562

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05310, KAKENHI-PROJECT-16K15258
  • [Journal Article] Sprouty-Related Ena/Vasodilator-Stimulated Phosphoprotein Homology 1-Domain-Containing Protein-2 Critically Regulates Influenza A Virus-Induced Pneumonia.2016

    • Author(s)
      Ito T, Itakura J, Takahashi S, Sato M, Mino M, Fushimi S, Yamada M, Morishima T, Kunkel SL, Matsukawa A
    • Journal Title

      Crit Care Med

      Volume: Jan 11

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Journal Article] Spred-2 deficiency exacerbates lipopolysaccharide-induced acute lung inflammation in mice.2014

    • Author(s)
      Xu Y, Ito T, Fushimi S, Takahashi S, Itakura J, Kimura R, Sato M, Mino M, Yoshimura A, Matsukawa A
    • Journal Title

      PLoS One

      Volume: 9

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Journal Article] The in vivo fibrotic role of FIZZ1 in pulmonary fibrosis2014

    • Author(s)
      Liu T, Yu H, Ullenbruch M, Jin H, Ito T, Wu Z, Liu J, Phan SH.
    • Journal Title

      PLoS One

      Volume: 9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Journal Article] Spred-2 deficiency exacerbates lipopolysaccharide-induced acute lung inflammation in mice2014

    • Author(s)
      Xu Y, Ito T, Fushimi S, Takahashi S, Itakura J, Kimura R, Sato M, Mino M, Yoshimura A, Matsukawa A
    • Journal Title

      PLoS One

      Volume: 9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Journal Article] The in vivo fibrotic role of FIZZ1 in pulmonary fibrosis2014

    • Author(s)
      Liu T, Yu H, Ullenbruch M, Jin H, Ito T, Wu Z, Liu J, Phan SH
    • Journal Title

      PLoS One

      Volume: 9 Issue: 2 Pages: e88362-e88362

    • DOI

      10.1371/journal.pone.0088362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Journal Article] T helper 2 and regulatory T cell cytokine production by mast cells: A key factor in the pathogenesis of IgG4-related disease.2014

    • Author(s)
      Takeuchi, M., Sato, Y., Ohno, K., Tanaka, S., Takata, K., Gion, Y., Orita,Y., Ito, T., Tachibana, T. and Yoshino, T.
    • Journal Title

      Mod. Pathol.

      Volume: 27 Issue: 8 Pages: 1126-1136

    • DOI

      10.1038/modpathol.2013.236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590077, KAKENHI-PROJECT-24591447, KAKENHI-PROJECT-25860296, KAKENHI-PROJECT-26293078
  • [Journal Article] MHV68 Latency Modulates the Host Immune Response to Influenza A Virus2013

    • Author(s)
      Saito F, Ito T, Connett JM, Schaller MA, Carson WF 4th, Hogaboam CM, Rochford R, Kunkel SL
    • Journal Title

      Inflammation

      Volume: 36 Issue: 6 Pages: 1295-1303

    • DOI

      10.1007/s10753-013-9668-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Journal Article] Redox-active protein thioredoxin-1 administration ameliorates influenza A virus (H1N1)-induced acute lung injury in mice.2013

    • Author(s)
      Yashiro M, Tsukahara H, Matsukawa A, Yamada M, Fujii Y, Nagaoka Y, Tsuge M, Yamashita N, Ito T, Yamada M, Masutani H, Yodoi J, Morishima T
    • Journal Title

      Crit Care Med.

      Volume: 41 Pages: 171-181

    • NAID

      120005300241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Journal Article] Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells2013

    • Author(s)
      Yoshimura T, Howard OM, Ito T, Kuwabara M, Matsukawa A, Chen K, Liu Y, Liu M, Oppenheim JJ, Wang JM
    • Journal Title

      PLoS One

      Volume: 8 Issue: 3 Pages: e58791-e58791

    • DOI

      10.1371/journal.pone.0058791

    • NAID

      120005703799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Journal Article] Cutting needle biopsy combined with immunohistochemical study of myeloperoxidase for the diagnosis of histiocytic necrotizing lymphadenitis2013

    • Author(s)
      Hanakawa H, Orita Y, Sato Y, Takeuchi M, Ohno K, Iwaki N, Ito T, Nishizaki K, Yoshino T
    • Journal Title

      Acta oto-laryngologica

      Volume: 133 Issue: 12 Pages: 1328-1332

    • DOI

      10.3109/00016489.2013.824112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Journal Article] Clinicopathologic analysis of IgG4-related skin disease.2013

    • Author(s)
      Sato Y, Takeuchi M, Takata K, Ohno K, Iwaki N, Orita Y, Goto N, Hida AI, Iwamoto T, Asano N, Ito T, Hanakawa H, Yanai H, Yoshino T.
    • Journal Title

      Mod Pathol.

      Volume: 26 Issue: 4 Pages: 523-532

    • DOI

      10.1038/modpathol.2012.196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590398, KAKENHI-PROJECT-24591447, KAKENHI-PROJECT-24790350, KAKENHI-PROJECT-25860296
  • [Patent] ビーズ担体を用いたcDNA増幅方法2019

    • Inventor(s)
      松島 綱治, 七野 成之、青木 寛泰、伊藤 哲、上羽 悟史
    • Industrial Property Rights Holder
      松島 綱治, 七野 成之、青木 寛泰、伊藤 哲、上羽 悟史
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-129017
    • Filing Date
      2019
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] COPDにおける病態及び制御の話題 COPDにおける再生医療の可能性2023

    • Author(s)
      伊藤 利洋,室 繁郎
    • Organizer
      第63回日本呼吸器学会学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K07632
  • [Presentation] HLA-F blockade restored the cytotoxicity of NK cells against colorectal cancer.2023

    • Author(s)
      Noriko Ouji-sageshima, Masahiro Kitabatake, Ryutaro Furukawa, Toshihiro Ito
    • Organizer
      第53回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07246
  • [Presentation] COPDにおける再生医療の可能性2023

    • Author(s)
      伊藤 利洋,室 繁郎
    • Organizer
      第63回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K08573
  • [Presentation] 高脂肪食投与ラットに対する柿タンニンの影響2023

    • Author(s)
      松下美稀、大園千晴、餅田尚子、北畠正大、伊藤利洋、菊﨑泰枝、栢野新市、松村羊子
    • Organizer
      第 62 回 日本栄養・食糧学会 近畿支部大会
    • Data Source
      KAKENHI-PROJECT-21K11587
  • [Presentation] 肺線維症合併肺癌においてT-regが腫瘍微小環境のCD8+Tcellと予後に与える影響の検討2023

    • Author(s)
      佐藤 一郎,本津 茂人,藤岡 伸啓,川口 剛史,澤端 章好,北畠 正大,伊藤 利洋,室 繁郎
    • Organizer
      第64回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K07632
  • [Presentation] びまん性肺疾患 病因・病態2 特発性肺線維症患者由来肺線維芽細胞におけるIGF-1(Insulin-like growth factor 1)の役割 患者肺検体の解析から2023

    • Author(s)
      西村 知子,北畠 正大,王寺(下嶋) 典子,齊藤 正一郎,古川 龍太郎,本津 茂人,川口 剛史,澤端 章好,室 繁郎,伊藤 利洋
    • Organizer
      第63回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-23K07632
  • [Presentation] 特発性肺線維症患者由来肺線維芽細胞におけるIGF-1(Insulin-like growth factor 1)の役割:患者肺検体の解析から2023

    • Author(s)
      西村 知子、北畠 正大、王寺(下嶋) 典子、齊藤 正一郎、古川 龍太郎、本津 茂人、川口 剛史、澤端 章好、室 繁郎、伊藤 利洋
    • Organizer
      第63回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K08573
  • [Presentation] 高脂肪食投与ラットの腸内細菌叢に対する柿タンニンの影響2023

    • Author(s)
      大園千晴、松下美稀、餅田尚子、北畠正大、伊藤利洋、菊﨑泰枝、栢野新市、松村羊子
    • Organizer
      第 62 回 日本栄養・食糧学会 近畿支部大会
    • Data Source
      KAKENHI-PROJECT-21K11587
  • [Presentation] 腫瘍細胞に発現するHLA-F分子を標的とした新規免疫療法の開発2023

    • Author(s)
      王寺(下嶋)典子、石谷昭子、Daniel E Geraghty、北畠正大、古川龍太郎、伊藤利洋
    • Organizer
      第31回日本組織適合性学会大会
    • Data Source
      KAKENHI-PROJECT-21K07246
  • [Presentation] Antitumor effect of anti-HLA-F antibody on colon cancer in patient-derived xenografts (PDX) model.2022

    • Author(s)
      Noriko Ouji-sageshima, Masahiro Kitabatake, Ryutaro Furukawa, Toshihiro Ito
    • Organizer
      第51回日本免疫学会学術集会(The 51th Annual Meeting of the Japanese Society for Immunology)
    • Data Source
      KAKENHI-PROJECT-21K07246
  • [Presentation] 特発性肺線維症におけるIGF-1(Insulin-link Growth Factor-1)の役割:患者肺検体の解析から2022

    • Author(s)
      西村知子,北畠正大,王寺典子,齊藤正一郎,古川龍太郎,本津茂人,川口剛史,澤端章好,室 繁郎,伊藤利洋
    • Organizer
      第62回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K08573
  • [Presentation] Angiopoietin-link 4は肺線維症の病態を制御する―肺線維症患者肺検体とマウスモデルでの解析2022

    • Author(s)
      齊藤正一郎,北畠正大,王寺典子,古川龍太郎,西村知子,本津茂人,川口剛史,澤端章好,室 繁郎,伊藤利洋
    • Organizer
      第62回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K08573
  • [Presentation] The critical role of regulatory T cells in the development of lung cancer with pulmonary fibrosis2021

    • Author(s)
      [Nishioka T,Kitabatake M,Ouji-Sageshima N,Hontsu S,Muro S,Ito T
    • Organizer
      第61回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K08573
  • [Presentation] Angiopoietin like 4 plays a critical role in the development of pulmonary fibrosis2021

    • Author(s)
      Masahiro Kitabatake, Shoichiro Saito, Noriko Ouji-Sageshima, Akihisa Oda, Atsushi Hara, Tatsuro Ogawa, Shigeyuki Shichino, Satoshi Ueha, Kouji Matsushima, Toshihiro Ito
    • Organizer
      第50回日本免疫学会学術集会(The 50th Annual Meeting of the Japanese Society for Immunology)
    • Data Source
      KAKENHI-PROJECT-21K07246
  • [Presentation] Histone modification enzyme SET domain bifurcated 2 (Setdb2) contributes to the pathogenesis of acute respiratory distress syndrome (ARDS) in murine model2021

    • Author(s)
      Shota Sonobe, Masahiro Kitabatake, Atsushi Hara, Makiko Konda, Ryutaro Furukawa, Tomoko Nishimura, Noriko Ouji-Sagaeshima, Shiki Takamura, Toshihiro Ito
    • Organizer
      第50回日本免疫学会学術集会(The 50th Annual Meeting of the Japanese Society for Immunology)
    • Data Source
      KAKENHI-PROJECT-21K07246
  • [Presentation] HLA-F as a new target molecule for cancer immunotherapy of colon cancer2021

    • Author(s)
      Noriko Ouji-sageshima, Masahiro Kitabatake, Ryutaro Furukawa, Toshihiro Ito
    • Organizer
      第50回日本免疫学会学術集会(The 50th Annual Meeting of the Japanese Society for Immunology)
    • Data Source
      KAKENHI-PROJECT-21K07246
  • [Presentation] Persimmon-derived tannin has antiviral effects in a Syrian hamster model of SARS-CoV-2 infection.2021

    • Author(s)
      Ryutaro Furukawa, Noriko Ouji Sageshima, Masahiro Kitabatake, Toshihiro Ito
    • Organizer
      第50回日本免疫学会学術集会(The 50th Annual Meeting of the Japanese Society for Immunology)
    • Data Source
      KAKENHI-PROJECT-21K07246
  • [Presentation] 特発性肺線維症におけるAngiopoietin-like 4の役割-ヒト肺検体とマウスモデルでの検討2020

    • Author(s)
      齊藤正一郎, 北畠正大, 王寺典子, 熊本牧子, 西村知子, 本津茂人, 安川元章, 川口剛史, 澤端章好, 谷口繁樹, 室繁郎, 伊藤利洋
    • Organizer
      第61回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K08661
  • [Presentation] エラスターゼ誘導肺気腫マウスモデルに対するヒト脂肪由来間葉系幹細胞療法の有用性の検討2020

    • Author(s)
      藤岡伸啓,北畠正大,熊本牧子,王寺典子,藤田幸男,本津茂人,山内基雄,吉川雅則,室 繁郎,伊藤利洋.
    • Organizer
      第60回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K08573
  • [Presentation] エピジェネティクスによる重症インフルエンザウイルス感染症の病態解明から創薬展開へ2020

    • Author(s)
      伊藤利洋、今北菜津子、王寺典子、北畠正大
    • Organizer
      日本薬学会第140年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K08412
  • [Presentation] Immune and epigenetic regulation through histone-lysine N-methyltransferase Setdb2 during severe influenza virus infection2020

    • Author(s)
      Toshihiro Ito, Natsuko Imakita, Atsushi Hara, Noriko Ouji-Sageshima, Masahiro Kitabatake
    • Organizer
      IMMUNOLOGY 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] エピジェネティクスによる重症インフルエンザウイルス感染症の病態解明から創薬展開へ2020

    • Author(s)
      伊藤 利洋、今北 菜津子、王寺 典子、北畠 正大
    • Organizer
      日本薬学会140年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] 特発性肺線維症におけるAngiopoietin-like 4の役割―ヒト肺検体とマウスモデルでの検討2020

    • Author(s)
      齊藤正一郎,北畠正大,王寺典子,熊本牧子,西村知子,本津茂人,安川元章,川口剛史,澤端章好,谷口繁樹,室 繁郎,伊藤利洋.
    • Organizer
      第60回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K08573
  • [Presentation] 肺線維症の病因・病態 特発性肺線維症におけるAngiopoietin-like 4の役割 ヒト肺検体とマウスモデルでの検討2020

    • Author(s)
      斎藤正一郎、北畠正大、王寺典子、熊本牧子、西村知子、本津茂人、安川元章、川口剛史、澤端章好、谷口繁樹、室繁郎、伊藤利洋
    • Organizer
      第60回日本呼吸器学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09663
  • [Presentation] Anti CD4 Monoclonal Antibody Immunotherapy Exerts an Antitumor Effect by Replacing the T Cell Receptor Repertoire in Patients with Gastrointestinal Cancer.2019

    • Author(s)
      Aoki H, Shitara K、Ueha S、Shichino S、Ogiwara H、Nakatsura T、Suzuki T、Shimomura M、Yoshikawa T、Shoda K、Kitano S、Yamashita M、Nakayama T、Sato A、Kuroda Sakiko、Wakabayashi Masashi、Nomura Shogo、Yokochi Shoji、Ito Satoru、Matsushima Kouji、Doi Toshihiko
    • Organizer
      AACR Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Cigarette smoke has different effects on inflammatory bowel disease model through mucosal immunity and gut microbiota2019

    • Author(s)
      Nishioka Tatsuki, Kitabatake Masahiro. Ouji-Sageshima Noriko, Nishimura Tomoko, Ito Toshihiro
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] Histone modification enzyme SET domain bifurcated 2 (Setdb2) regulates acute inflammation in murine models of acute respiratory distress syndrome (ARDS)2019

    • Author(s)
      Sonobe Shota, Kitabatake Masahiro, Imakita Natsuko, Hara Atsushi, Furukawa Ryutaro, Nishimura Tomoko, Ouji-Sageshima Noriko, Ito Toshihiro
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] The contribution of hirtone-lysine N-methyltransferase Setdb2 in high mortality of secondary bacterial pneumonia via regulating cytokines and chemokines in macrophages.2019

    • Author(s)
      Hara Atushi, Kitabatake Masahiro. Ouji-Sageshima Noriko, Sonobe Shota, Imakita Natsuko, Furukawa Ryutaro, Oda Akihisa, Ito Toshihiro
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] Persimmon-derived tannin attenuates the murine model of ulcerative colitis through the alternation of gut environment2019

    • Author(s)
      Kitabatake Masahiro, Matsumura Yoko, Ouji-Sageshima Noriko, Ito Toshihiro.
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] HLA-F could be a specific target for both pathological diagnosis and cancer immunotherapy of malignant colon cancer2019

    • Author(s)
      Noriko Ouji-Sageshima, Tatsuki Nishioka, Masahiro Kitabatake, Daniel. E Geraghty, Akiko Ishitani, Toshihiro Ito
    • Organizer
      第48回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-18K07300
  • [Presentation] 新規高感度包括的1細胞トランスクリプトーム法の開発と線維化肺における解析2019

    • Author(s)
      七野成之, 橋本真一, 上羽悟史, 北畠正大, 伊藤利洋, 松島綱治
    • Organizer
      第5回骨免疫学会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] HLA-F分子を標的とした免疫療法の開発に向けて2019

    • Author(s)
      王寺-下嶋 典子、石谷 昭子、Daniel E Geraghty、 伊藤 利洋
    • Organizer
      第28回 日本組織適合性学会大会
    • Data Source
      KAKENHI-PROJECT-18K07300
  • [Presentation] Histon modification enzyme SET domain bifurcated 2 (Setdb2) regulates acute inflammation in murine model of acute respiratory distress syndrome (ARDS)2019

    • Author(s)
      Sonobe S, Kitabatake M, Imakita N, Hara A, Furukawa R, Nishimura T, Ouji-Sageshima N, Ito T.
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08412
  • [Presentation] The contribution of histone-lysine N-methyltransferase Setdb2 in high mortality of secondary bacterial pneumonia via regulating cytokines and chemokines in macrophages2019

    • Author(s)
      Hara A, Kitabatake M, Ouji-Sageshima N, Sonobe S, Imakita N, Furukawa R, Oda A, Ito T.
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08412
  • [Presentation] 悪性腫瘍におけるHLA-F発現について2019

    • Author(s)
      王寺(下嶋)典子、石谷昭子、Daniel E Geraghty、伊藤利洋
    • Organizer
      第16回日本組織適合性学会近畿地方会
    • Data Source
      KAKENHI-PROJECT-18K07300
  • [Presentation] The safety assessment of crizotinib and alectinib from real world date of 840 ALK-inhibitor naive patients with NSCLC harboring ALK-rearrangement (WJOG9516L)2019

    • Author(s)
      K. Kunimasa, K. Ito, T. Yamanaka, D. Fujimoto, M. Mori, K. Maeno, K. Tomomatsu, A. Tamura, H. Tanaka, S. Watanabe, S. Teraoka, O. Hataji, K. Suzuki, S. Hontsu, S. Hara15, A. Bessho, A. Kubo, M. Okuno, K. Nakagawa, N. Yamamoto
    • Organizer
      ESMO 2019 Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09663
  • [Presentation] 担がん患者における抗CD4抗体投与後のTCRレパトア変動2019

    • Author(s)
      青木寛泰, 上羽悟史, 七野成之, 荻原春, 設樂紘平, 中面哲也, 鈴木利宙, 下村真菜美, 北野滋久, 山下万貴子, 伊藤哲, 土井俊彦, 松島綱治
    • Organizer
      第28回日本癌病態治療研究会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] HLA-F could be a specific target for both pathological diagnosis and cancer immunotherapy of malignant colon cancer2019

    • Author(s)
      Ouji-Sageshima Noriko, Nishioka Tatsuki, Kitabatake Masahiro, Geraghty E. Daniel , Ishitani Akiko, Ito Toshihiro
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] 特発性肺線維症に対する脂肪由来間葉系幹細胞療法への試み2019

    • Author(s)
      伊藤利洋 檜山愛子 熊本牧子 北畠正大 王寺典子 本津茂人 安川元章 川口剛史 澤端章好 谷口繁樹 室 繁郎
    • Organizer
      第59回 日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-17K09663
  • [Presentation] HLA-F分子を標的とした免疫療法の開発に向けて2019

    • Author(s)
      王寺-下嶋典子、石谷昭子、Daniel E Geraghty、伊藤利洋
    • Organizer
      第28回日本組織適合性学会大会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] Persimmon-derived tannin attenuates the murine model of ulcerative colitis through the alteration of gut environment2019

    • Author(s)
      Masahiro Kitabatake, Yoko Matsumura, Noriko Ouji-Sageshima, and Toshihiro Ito
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K11148
  • [Presentation] Adipose derived mesenchymal stem cells (ASCs) have anti-fibrotic effects in lung fibroblasts from Idiopathic pulmonary fibrosis (IPF) patients2018

    • Author(s)
      Aiko Hiyama, Noriko Ouji-Sageshima, Masahiro Kitabatake, Makiko Kumamoto, Noriyoshi Sawabata, Toshihiro Ito
    • Organizer
      International Society for Stem Cell Research Annual Meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] Enhanced expression of HLA-F is critically related with tumor malignancy2018

    • Author(s)
      Noriko- Ouji-Sageshima, Akiko Ishitani, Daniel E. Geraghty, Nastuk Imakita, Shota Sonobe, Masahiro Kitabatake, Toshihiro Ito
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] The critical role of Epigenetic regulation by Setdb2 in acute respiratory distress syndrome (ARDS) model2018

    • Author(s)
      Shota Sonobe, Masahiro Kitabatake, Noriko Ouji-Sageshima, Natsuko Imakita, Toshihiro Ito
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] Histone modification enzyme Setdb2 plays a critical role in a murine model of influenza associated encephalopathy.2018

    • Author(s)
      Natsuko Imakita, Masahiro Kitabatake, Noriko Ouji-Sageshima, Toshihiro Ito
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] 重症インフルエンザウイルス感染症の免疫機構2018

    • Author(s)
      伊藤 利洋
    • Organizer
      第410回川崎医学会講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] Cigarette smoke suppresses the ulcerative colitis model through the alteration of immune response and microbiota.2018

    • Author(s)
      Masahiro Kitabatake, Noriko Ouji-Sageshima, Natsuko Imakita, Toshihiro Ito
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] The critical role of epigenetic regulation by Setdb2 in acute respiratory distress syndrome (ARDS) model.2018

    • Author(s)
      Sonobe S, Kitabatake M, Ouji-Sageshima N, Imakita N, Ito T
    • Organizer
      第48回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18K08412
  • [Presentation] Adipose-derived mesenchymal stem cell (ADSC) attenuates pulmonary fibrosis in both bleomycin-induced and humanized mice model2018

    • Author(s)
      Toshihiro Ito, Masahiro Kitabatake, Makiko Kumamoto, Aiko Hiyama, Natsuko Imakita, Noriyoshi Sawabata, Noriko Ouji-Sageshima
    • Organizer
      International Society for Stem Cell Research Annual Meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] Enhanced expression of HLA-F is critically related with tumor malignancy2018

    • Author(s)
      Noriko Ouji-sageshima, Akiko Ishitani, Daniel E Geraghty, Natsuko Imakita, Shota Sonobe, Masahiro Kitabatake, Toshihiro Ito
    • Organizer
      The 47th Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-18K07300
  • [Presentation] Histone modification enzyme Setdb2 plays critical role in a murine model of influenza associated encephalopathy.2018

    • Author(s)
      Imakita N, Kitabatake M, Ouji-Sageshima N, Ito T
    • Organizer
      第48回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18K08412
  • [Presentation] 抗CD4抗体とDLIを併用した同種造血幹細胞移植による低免疫原性固形がん治療の可能性2017

    • Author(s)
      上羽 悟史、石渡 義郎、_地祥司、伊藤哲、松島綱治
    • Organizer
      第26回 日本癌病態治療研究会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] An anti-CD4 depleting antibody reverses regulatory T cell-induced suppression of dendritic cells while preventing non-specific CD4+ T cell responses in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Haru Ogiwara, Shoji Yokochi, Yoshiro Ishiwata, Francis Shand, Shohei Hori, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      AACR Annual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] The critical role of HLA class Ib proteins, HLA-E and HLA-F, expressed on tumor cells2017

    • Author(s)
      Ouji-Sageshima Noriko, Ishitani Akiko, Imakita Natsuko, Sonobe Shota, Kitbatake Masahiro, Daniel E Geraghty, Ito Toshihiro
    • Organizer
      The 46th Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-15K08650
  • [Presentation] CD8+ T cells play a critical role for the murine model of immune reconstitution inflammatory syndrome2017

    • Author(s)
      Masahiro Kitabatake, Mitsuru Konishi, Yoko Matsumura, Noriko Ouji-Sageshima, Natsuko Imakita, Toshihiro Ito
    • Organizer
      The 46th Annual Meeting of The Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] An anti-CD4 depleting antibody reverses regulatory T cell-induced suppression of dendritic cells while preventing non-specific CD4+ T cell responses in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Haru Ogiwara, Shoji Yokochi, Yoshiro Ishiwata, Francis Shand, Shohei Hori, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      36th Sapporo International_Cancer Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第21回日本がん免疫学会総会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] The contribution of histone methyltransferase Setdb2 in the pathogenesis of influenza associated encephalopathy2017

    • Author(s)
      Natsuko Imakita, Masahiro Kitabatake, Noriko Ouji-Sageshima, Shota Sonobe, Toshihiro Ito
    • Organizer
      The 46th Annual Meeting of The Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] 肺線維症に対する脂肪由来間葉系幹細胞治療の試み―新規マウスモデルによる検討2017

    • Author(s)
      熊本牧子、檜山愛子、北畠正大、王寺典子、藤岡伸啓、吉川雅則、木村 弘、伊藤利洋
    • Organizer
      第16回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-17K09663
  • [Presentation] 腫瘍細胞株におけるHLA-E、-F、-G分子の発現2017

    • Author(s)
      王寺-下嶋 典子、石谷 昭子、Daniel E Geraghty、伊藤 利洋
    • Organizer
      第26回日本組織適合性学会大会
    • Data Source
      KAKENHI-PROJECT-15K08650
  • [Presentation] Does HLA-G in plasma from pregnant woman inhibit the rejection of fetus?2016

    • Author(s)
      Noriko OUJI-SAGESHIMA, Akiko ISHITANI, Daniel E Geraghty, Toshihiro ITO
    • Organizer
      第45回 日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-15K08650
  • [Presentation] HLA-Gは体外受精卵培養上清および妊婦血漿等体液中に存在するのか?2016

    • Author(s)
      下嶋典子、Daniel E Geraghty、石谷昭子、伊藤利洋
    • Organizer
      第31回 日本生殖免疫学会総会・学術集会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-15K08650
  • [Presentation] The critical role of histone methyltransferase Setdb2 in the pathogenesis of influenza associated encephalopathy2016

    • Author(s)
      Natsuko Imakita, Masahiro Kitabatake, Noriko Ouji-Sageshima, Toshihiro Ito
    • Organizer
      第45回日本免疫学会総会・学術集会
    • Place of Presentation
      沖縄コンベンションセンター
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-16H05310
  • [Presentation] 改良ELISA法による体外受精卵培養上清および妊婦血漿等体液中のHLA-Gの測定とその意義2016

    • Author(s)
      王寺-下嶋典子、Daniel E Geraghty、石谷昭子、伊藤利洋
    • Organizer
      第25回 日本組織適合性学会大会
    • Place of Presentation
      北海道大学
    • Year and Date
      2016-10-22
    • Data Source
      KAKENHI-PROJECT-15K08650
  • [Presentation] 移植患者末梢血における HLA-F、HLA-Gの発現解析―移植片生着との関連性について―」2015

    • Author(s)
      下嶋典子、貝森淳哉、市丸直嗣、吉澤淳、一戸辰夫、森井武志、長谷川淳、米田龍生、高原史郎、上本伸二、吉田克法、羽竹勝彦、伊藤利洋、Daniel E Geraghty、石谷昭子
    • Organizer
      第24回日本組織適合性学会大会(水戸)
    • Place of Presentation
      ホテルレイクビュー水戸
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-15K08650
  • [Presentation] Spred-2 deficiency exacerbates LPS_induced acute lung inflammation2015

    • Author(s)
      楊旭、伊藤利洋、伏見聡一郎、高橋索真、板倉淳哉、佐藤美和、美野愛、松川昭博
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] The relation between the expression of both HLA-F and HLA-G on PBMC from pretransplant and posttransplant patients and the graft survival.2015

    • Author(s)
      Noriko Ouji-Sageshima, Daniel E Geraghty, Akiko Ishitani, Toshihiro Ito
    • Organizer
      日本免疫学会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-15K08650
  • [Presentation] 創傷治癒はSpred-2欠損で短縮する2015

    • Author(s)
      河原明奈、板倉淳哉、小田晋輔、伏見聡一郎、伊藤利洋、松川昭博
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] Spred-2 deficiency exacebates Influenza A Virus (H1N1)-induced Pneumonia2013

    • Author(s)
      Toshihiro Ito, Akihiko Yoshimura, and Akihiro Matsukawa
    • Organizer
      15th International Congress of Immunology
    • Place of Presentation
      ミラノ(イタリア)
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Presentation] Epigenetic regulation of secondary bacterial pneumonia following influenza virus infection2013

    • Author(s)
      ITO Toshihiro, KUNKEL L. Steven, MATSUKAWA Akihiro
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Presentation] Spred2欠損マウスは敗血症抵抗性を示す2013

    • Author(s)
      板倉淳哉, 伊藤利洋, 佐藤美和, 美野愛, 伏見聡一郎, 松川昭博
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] A型インフルエンザウイルス(H1N1)感染とMAPK経路2013

    • Author(s)
      松川昭博、伊藤利洋
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] T細胞Suppressor of Cytokine Signaling 5 (SOCS5)の過剰発現はLPSトレランス効果を増強する2013

    • Author(s)
      伊藤利洋、板倉淳哉、佐藤美和、美野愛、伏見聡一郎、松川昭博
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Presentation] Spred2発現ベクターの作製とその応用2013

    • Author(s)
      篠倉美理, 木村亮二郎, 伊藤利洋, 松川昭博
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] Spred-2 deficiency exacebates Influenza A Virus (H1N1)-induced Pneumonia2013

    • Author(s)
      Ito T, Yoshimura A, Matsukawa A
    • Organizer
      15th International Congress of Immunology
    • Place of Presentation
      Milan
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] The impact of Spred-2 on colonic repair in mice with DSS-undued colitis2013

    • Author(s)
      Takahashi S, Fushimi S, Ito T, Inokuchi T, Nakarai A, Akita M, Harada K, Hiraoka S, Okada H, Yamamoto K, Matsukawa A
    • Organizer
      UEG Week 2013
    • Place of Presentation
      Berlin
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] Ras/ERK系と大腸粘膜治癒―Ras/ERK系の阻害因子Spred-2の解析を通じてー2013

    • Author(s)
      高橋索真、平岡佐規子、伏見聡一郎、伊藤利洋、板倉淳哉、木村亮治郎、楊旭、篠倉美理、中川裕貴、住居優一、竹井大介、井口俊博、半井明日香、森藤油記、秋田光洋、原田馨太、岡田裕之、松川昭博、山本和秀
    • Organizer
      第50回日本消化器免疫学会総会
    • Place of Presentation
      所沢
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] Spred-2 deficiency exacebates Influenza A Virus (H1N1)-induced Pneumonia2013

    • Author(s)
      Toshihiro Ito
    • Organizer
      15th International Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-23790445
  • [Presentation] Notch system in the linkage of innate and adaptive immunity in pulmonary infectious diseases.2013

    • Author(s)
      Ito T, Matsukawa A
    • Organizer
      21th International Symposium on Molecular Cell Biology of Macrophages 2013
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] エピジェネティクスを介した難治性感染症に対する新たな治療戦略2012

    • Author(s)
      伊藤利洋
    • Organizer
      第2回ブレインストーミングin直島
    • Data Source
      KAKENHI-PROJECT-23790445
  • [Presentation] The Critical Role of Spred-2 in Influenza A Virus (H1N1)-induced Pneumonia2011

    • Author(s)
      伊藤利洋、吉村昭彦、松川昭博
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      千葉市美浜区
    • Data Source
      KAKENHI-PROJECT-23790445
  • [Presentation] The critical role of epigenetic regulation against secondary bacterial pneumonia following influenza virus infection

    • Author(s)
      Toshihiro Ito, Steven L. Kunkel, Akihiro Matsukawa
    • Organizer
      The 13th Awaji International Forum on Infection and Immunity in Nara
    • Place of Presentation
      奈良県新公会堂
    • Year and Date
      2014-09-23 – 2014-09-26
    • Data Source
      KAKENHI-PROJECT-25860296
  • [Presentation] インフルエンザ(H1N1)感染症ならびに二次性細菌性肺炎のエピジェネティクス解析

    • Author(s)
      伊藤利洋、板倉淳哉、河原明奈、小田晋輔、伏見聡一郎、松川昭博
    • Organizer
      日本病理学会総会
    • Place of Presentation
      広島
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] Spred2欠損マウスにおける敗血症抵抗性のメカニズム

    • Author(s)
      板倉淳哉、小田晋輔、河原明奈、佐藤美和、美野愛、伏見聡一郎、伊藤利洋,松川昭博
    • Organizer
      日本病理学会総会
    • Place of Presentation
      広島
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] 間質性肺炎モデルにおけるSpred-2の役割

    • Author(s)
      水田亮、伊藤利洋、板倉淳哉、伏見聡一郎、松川昭博
    • Organizer
      日本病理学会総会
    • Place of Presentation
      広島
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25293095
  • [Presentation] インフルエンザウィルス(H1N1)肺炎におけるSpred-2の重要な役割

    • Author(s)
      伊藤 利洋
    • Organizer
      第40回日本免疫学会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23790445
  • 1.  Kitabatake Masahiro (60457588)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 32 results
  • 2.  Ouji-Sageshima Noriko (30398432)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 24 results
  • 3.  Muro Shigeo (60344454)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 4.  Yoko Matsumura (80412154)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 5.  MATSUKAWA AKIHIRO (90264283)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 20 results
  • 6.  栢野 新市 (40412150)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 7.  田辺 直也 (30805817)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  佐藤 晋 (40378691)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 9.  Obayashi Chiho (90223940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Nakai Tokiko (00619538)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Shigeto Hontsu (90458034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  Kumamoto Makiko (10623522)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  Matsushima Kouji (50222427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 14.  石谷 昭子 (40112544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 15.  笠原 敬 (50405403)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  友田 恒一 (90364059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  橋本 真一 (00313099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 18.  上羽 悟史 (00447385)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 19.  七野 成之 (70822435)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 20.  吉川 雅則 (80271203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 21.  今北 英高 (00412148)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TAKAHASHI Sakuma
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 23.  FUSHIMI Soichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 24.  TAIRA Asako
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 25.  ITAKURA Junya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 26.  WATANABE Haruyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SATO Miwa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 28.  KAWAGUCHI Ryuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  ISHII Sanae
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  NOGAMI Keiji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  ODA Akihisa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  永田 喜三郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  宮澤 正顕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  園部 奨太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  阿部 訓也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  田中 智之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  藤田 幸男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  島野 仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  本園 千尋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  吉野 正
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  高田 尚良
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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