Kumai Takumi 熊井琢美

… Alternative Names

KUMAI Takumi 熊井琢美

Less

Researcher Number	00596306
Affiliation (Current)	2022: 旭川医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2018 – 2022: 旭川医科大学, 医学部, 特任講師 2016 – 2017: 旭川医科大学, 医学部, 助教 2012 – 2014: 旭川医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology / Basic Section 58080:Gerontological nursing and community health nursing-related
Keywords	Principal Investigator 頭頸部癌 / 腫瘍免疫 / ペプチドワクチン / ペプチドワクチン療法 / EGFR / c-Met / ヘルパーT細胞 / EGFR阻害薬 / HLA / 国際情報交換 … More / アジュバント / 分子標的薬 / 腫瘍抗原 / バイオマーカー / 免疫チェックポイント / ペプチド / ワクチン … More Except Principal Investigator 鼻性NK/T細胞リンパ腫 / NK/T細胞リンパ腫 / Epstein-Barr virus / LMP1 / CD70 / chemokine / CCR4 / miR-15a / 頭頸部外科学 / 悪性リンパ腫 / 悪性腫瘍 / 免疫チェックポイント / ペプチドワクチン / EBウイルス / 腫瘍抗原 / 免疫抑制 / 免疫療法 / 頭頸部癌 / 高齢者 / 化学放射線療法 / 口腔内評価 / 粘膜炎 / ペプチド / ワクチン / 扁桃病巣疾患 Less

扁桃における糖鎖不全IgAとT細胞サブセットを中心としたIgA腎症の病態解明
- Principal Investigator
  
  寒風澤知明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Asahikawa Medical College
鼻性NK/T細胞リンパ腫を治癒に導く複合的免疫療法の確立
- Principal Investigator
  
  原渕保明
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Hokuto Hospital, Social care corporation Hokuto (Tumor Medicine)
  Asahikawa Medical College
頭頸部癌に対する免疫チェックポイント阻害薬のバイオマーカー探索Principal Investigator
- Principal Investigator
  
  熊井琢美
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Asahikawa Medical College
高齢頭頸部癌患者の化学放射線療法による有害事象に対する口腔内評価ツールの開発
- Principal Investigator
  
  野中雅人
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  Asahikawa Medical College
Developing novel immunotherapy against nasal NK/T cell lymphoma
- Principal Investigator
  
  Harabuchi Yasuaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Asahikawa Medical College
Combination of molecular-targeted therapy with peptide vaccinePrincipal Investigator
- Principal Investigator
  
  Kumai Takumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Asahikawa Medical College
A foundational study for targeted therapy against EB virus and tumor growth factor in nasal NK/T-cell lymphoma
- Principal Investigator
  
  HARABUCHI Yasuaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Asahikawa Medical College
HER family targeted immunotherapy against head and neck squamous cancerPrincipal Investigator
- Principal Investigator
  
  KUMAI Takumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Asahikawa Medical College

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery2021
- Author(s)
  Kono Michihisa、Kumai Takumi、Hayashi Ryusuke、Yamaki Hidekiyo、Komatsuda Hiroki、Wakisaka Risa、Nagato Toshihiro、Ohkuri Takayuki、Kosaka Akemi、Ohara Kenzo、Kishibe Kan、Takahara Miki、Katada Akihiro、Hayashi Tatsuya、Celis Esteban、Kobayashi Hiroya、Harabuchi Yasuaki
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: epub
- DOI
  10.1007/s00262-021-02940-5
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] A critical role of STING-triggered tumor-migrating neutrophils for anti-tumor effect of intratumoral cGAMP treatment2021
- Author(s)
  Nagata Marino、Kosaka Akemi、Yajima Yuki、Yasuda Syunsuke、Ohara Mizuho、Ohara Kenzo、Harabuchi Shohei、Hayashi Ryusuke、Funakoshi Hiroshi、Ueda Jun、Kumai Takumi、Nagato Toshihiro、Oikawa Kensuke、Harabuchi Yasuaki、Esteban Celis、Ohkuri Takayuki、Kobayashi Hiroya
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: epub
- DOI
  10.1007/s00262-021-02864-0
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Phosphorylated vimentin as an immunotherapeutic target against metastatic colorectal cancer2020
- Author(s)
  Ohara M, Ohara K, Kumai T, Ohkuri T, Nagato T, Hirata-Nozaki Y, Kosaka A, Nagata M, Hayashi R, Harabuchi S, Yajima Y, Oikawa K, Harabuchi Y, Sumi Y, Furukawa H, Kobayashi H.
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: ePub Pages: 989-999
- DOI
  10.1007/s00262-020-02524-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-19K07452
[Journal Article] Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma2020
- Author(s)
  Hayashi Ryusuke、Nagato Toshihiro、Kumai Takumi、Ohara Kenzo、Ohara Mizuho、Ohkuri Takayuki、Hirata-Nozaki Yui、Kosaka Akemi、Yasuda Syunsuke、Oikawa Kensuke、Kono Michihisa、Kishibe Kan、Takahara Miki、Katada Akihiro、Hayashi Tatsuya、Celis Esteban、Harabuchi Yasuaki、Kobayashi Hiroya et al
- Journal Title
  
  OncoImmunology
  
  Volume: 10 Pages: 1856545-1856545
- DOI
  10.1080/2162402x.2020.1856545
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Intratumoral STING activations overcome negative impact of cisplatin on antitumor immunity by inflaming tumor microenvironment in squamous cell carcinoma2020
- Author(s)
  Harabuchi S, Kosaka A, Yajima Y, Nagata M, Hayashi R, Kumai T, Ohara K, Nagato T, Oikawa K, Ohara M, Harabuchi Y, Ohkuri T, Kobayashi H.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 522 Pages: 408-414
- DOI
  10.1016/j.bbrc.2019.11.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-19K18791
[Journal Article] PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma.2019
- Author(s)
  Hirata-Nozaki Y, Ohkuri T, Ohara K, Kumai T, Nagata M, Harabuchi S, Kosaka A, Nagato T, Ishibashi K, Oikawa K, Aoki N, Ohara M, Harabuchi Y, Uno Y, Takei H, Celis E, Kobayashi H.
- Journal Title
  
  J Transl Med.
  
  Volume: 17
- DOI
  10.1186/s12967-019-1957-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] 頭頸部癌に対する癌ペプチドワクチン療法の開発2019
- Author(s)
  熊井琢美
- Journal Title
  
  Japanese Journal of Rhinology
  
  Volume: 58 Issue: 1 Pages: 107-108
- DOI
  10.7248/jjrhi.58.107
- NAID
  130007636230
- ISSN
  0910-9153, 1883-7077
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Cyclin-dependent kinase 1 and survivin as potential therapeutic targets against nasal natural killer/T-cell lymphoma2019
- Author(s)
  Nagato Toshihiro、Ueda Seigo、Takahara Miki、Kishibe Kan、Komabayashi Yuki、Kumai Takumi、Ohara Kenzo、Hirata-Nozaki Yui、Harabuchi Shohei、Hayashi Ryusuke、Ohkuri Takayuki、Bernasconi Michele、Nadal David、Kobayashi Hiroya、Harabuchi Yasuaki
- Journal Title
  
  Laboratory Investigation
  
  Volume: 99 Pages: 612-624
- DOI
  10.1038/s41374-018-0182-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Basic Science and Clinical Progress2019
- Author(s)
  Harabuchi Yasuaki、Takahara Miki、Kishibe Kan、Nagato Toshihiro、Kumai Takumi
- Journal Title
  
  Frontiers in Pediatrics
  
  Volume: 7 Pages: 141-141
- DOI
  10.3389/fped.2019.00141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-16K20223
[Journal Article] Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma2018
- Author(s)
  Ohara Kenzo、Ohkuri Takayuki、Kumai Takumi、Nagato Toshihiro、Nozaki Yui、Ishibashi Kei、Kosaka Akemi、Nagata Marino、Harabuchi Shohei、Ohara Mizuho、Oikawa Kensuke、Aoki Naoko、Harabuchi Yasuaki、Celis Esteban、Kobayashi Hiroya
- Journal Title
  
  Oncoimmunology
  
  Volume: 7
- DOI
  10.1080/2162402x.2018.1466771
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223, KAKENHI-PROJECT-17K16884
[Journal Article] 鼻性NK/T細胞リンパ腫に対する革新的免疫療法の開発2018
- Author(s)
  長門利純、熊井琢美,、高原幹、大栗敬幸、小林博也、Celis Esteban、原渕保明
- Journal Title
  
  耳鼻咽喉科免疫アレルギー
  
  Volume: 36 Pages: 15-22
- NAID
  130006619256
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Optimization of Peptide Vaccines to Induce Robust Antitumor CD4 T-cell Responses2017
- Author(s)
  Takumi Kumai, Sujin Lee, Hyun-Il Cho, Hussein Sultan, Hiroya Kobayashi, Yasuaki Harabuchi, and Esteban Celis
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 5 Pages: 1-12
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223
[Journal Article] Peptide vaccines in cancer ― old concept revisited2017
- Author(s)
  Takumi Kumai, Hiroya Kobayashi, Yasuaki Harabuchi and Esteban Celis
- Journal Title
  
  Current opinion in immunology
  
  Volume: 45 Pages: 1-7
- DOI
  10.1016/j.coi.2016.11.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223
[Journal Article] Assessment of the change in cetuximab induced ADCC activity of NK cells by steroid2016
- Author(s)
  Takumi Kumai, Kensuke Oikawa, Naoko Aoki, Shoji Kimura, Yasuaki Harabuchi, Hiroya Kobayashi
- Journal Title
  
  Head & Neck
  
  Volume: 38(3) Pages: 410-416
- DOI
  10.1002/hed.23906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460430, KAKENHI-PROJECT-24791735
[Journal Article] Novel targets for natural killer/T-cell lymphoma immunotherapy2016
- Author(s)
  Takumi Kumai
- Journal Title
  
  Immunotherapy
  
  Volume: 8 Pages: 45-55
- DOI
  10.2217/imt.15.103
- NAID
  120005954152
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04986, KAKENHI-PROJECT-25460430, KAKENHI-PROJECT-24791735
[Journal Article] Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma2015
- Author(s)
  Takumi Kumai, Takayuki Ohkuri, Toshihiro Nagato, Yoshinari Matsuda, Kensuke Oikawa, Naoko Aoki, Shoji Kimura, Esteban Celis, Yasuaki Harabuchi, Hiroya Kobayashi
- Journal Title
  
  Scientific reports
  
  Volume: 5 Pages: 16280-16280
- DOI
  10.1038/srep16280
- NAID
  120005690964
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460430, KAKENHI-PROJECT-24791735
[Journal Article] CCL17 and CCL22/CCR4 signaling is a strong candidate for novel targeted therapy against nasal natural killer/T-cell lymphoma2015
- Author(s)
  Takumi Kumai, Toshihiro Nagato, Hiroya Kobayashi, Yuki Komabayashi, Seigo Ueda, Kan Kishibe, Takayuki Ohkuri, Miki Takahara, Esteban Celis, Yasuaki Harabuchi
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: - Pages: 697-705
- DOI
  10.1007/s00262-015-1675-7
- NAID
  120005774022
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390385, KAKENHI-PROJECT-15H04986
[Journal Article] Helper T-cell based immunotherapy combined with adjuvants in head and neck squamous cell carcinoma2014
- Author(s)
  熊井　琢美、長門　利純、高原　幹、小林　博也、原渕　保明
- Journal Title
  
  Journal of Japan Society of Immunology & Allergology in Otolaryngology
  
  Volume: 32 Issue: 3 Pages: 185-190
- DOI
  10.5648/jjiao.32.185
- NAID
  130004697457
- ISSN
  0913-0691, 2185-5900
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791735
[Journal Article] EGFR inhibitors augment antitumour helper T-cell responses of HER family-specific immunotherapy.2013
- Author(s)
  T Kumai, Y Matsuda, K Oikawa, N Aoki, S Kimura, Y Harabuchi, E Celis and H Kobayashi
- Journal Title
  
  Br J Cancer.
  
  Volume: 577 Pages: 1-12
- DOI
  10.1038/bjc.2013.577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791735, KAKENHI-PROJECT-25460430
[Presentation] ペプチドを用いた免疫チェックポイント阻害薬のバイオマーカー探索2022
- Author(s)
  熊井琢美
- Organizer
  日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-20K09724
[Presentation] Peptide-reactive T cell response as a novel biomarker in head and neck cancer patients treated with anti-PD-1 antibody2021
- Author(s)
  熊井琢美
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-20K09724
[Presentation] C-met as an novel antigen in extranodal NK/T cell lymphoma, nasal type for helper T cell-based immunotherapy2021
- Author(s)
  Nozaki Y, Kumai T, Komatsuda H, Kono M, Yamaki H, Kishibe K, Takahara M, Hayashi T, Harabuchi Y
- Organizer
  The 19th International Symposium on Epstein-Barr Virus and associated diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03082
[Presentation] 鼻性NK/T細胞リンパ腫における免疫抑制サイトカインの検討2019
- Author(s)
  熊井琢美、長門利純、林隆介、原渕翔平、岸部幹、高原幹、林達哉、小林博也、原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] リン酸化抗原特異的T細胞を利用した悪性腫瘍に対するペプチドワクチン療法の基礎的解析2019
- Author(s)
  大原賢三, 熊井琢美, 長門利純, 林　隆介, 原渕翔平, 小林博也, 原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Expression of cyclin-dependent kinase 1 and survivin in nasal natural killer/T-cell lymphoma2019
- Author(s)
  Hayashi R, Nagato T, Harabuchi S, Kumai T, Kishibe K, Takahara M, Kobayashi H, Harabuchi Y
- Organizer
  ISIAN・IRS・ARS (RhinoWorld Chicago 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫における免疫抑制サイトカインの検討2019
- Author(s)
  熊井琢美, 長門利純, 岸部　幹, 高原　幹, 青木直子, 及川賢輔, 林　達哉, 小林博也, 原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫におけるCDK1とサバイビンの発現2019
- Author(s)
  熊井琢美, 長門利純, 高原　幹, 原渕保明
- Organizer
  第33回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫におけるCD74とMIFの発現2019
- Author(s)
  林　隆介, 長門利純, 原渕翔平, 熊井琢美, 岸部　幹, 高原　幹, 小林博也, 原渕保明
- Organizer
  第58回日本鼻科学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Expression and function of Epstein-Barr virus-encoded microRNAs in nasal natural killer/ T-cell lymphoma2019
- Author(s)
  Kishibe K, Komabayashi Y, Hayashi R, Kumai T, Takahara M, Harabuchi Y
- Organizer
  ISIAN・IRS・ARS (RhinoWorld Chicago 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫および上咽頭癌におけるCD74とMIFの発現2019
- Author(s)
  熊井琢美, 林　隆介, 長門利純, 原渕翔平, 岸部　幹, 高原　幹, 永田真莉乃, 矢島優己, 小坂　朱, 大栗敬幸, 及川賢輔, 小林博也, 原渕保明
- Organizer
  第16回EBウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫６７症例の臨床学的検討2019
- Author(s)
  高原　幹, 熊井琢美, 岸部　幹, 片田彰博, 林　達哉, 原渕保明
- Organizer
  第33回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Sustained persistence of IL-2 signaling enhances the antitumor effect of peptide vaccines2019
- Author(s)
  Kumai, T.//Sultan, H.//Harabuchi, Y.//Celis, E.
- Organizer
  American Association for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223
[Presentation] 頭頸部癌に対する癌ペプチドワクチン療法の開発2019
- Author(s)
  熊井琢美
- Organizer
  第32回日本耳鼻咽喉科学会北海道地方部会ブロック講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫におけるCD27の発現2019
- Author(s)
  長門利純, 林　隆介, 原渕翔平, 野﨑　結, 大原賢三, 熊井琢美, 岸部　幹, 高原　幹, 小林博也, 原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Expression of cell surface CD74 and macrophage migration inhibitory factor in malignant tumors of head and neck region2019
- Author(s)
  Hayashi R, Nagato T, Kumai T, Nagata M, Harabuchi S, Yajima Y, Kosaka A, Ohkuri T, Oikawa K, Kishibe K, Takahara M, Harabuchi Y, Kobayashi H
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Sustained persistence of IL-2 signaling enhances the antitumor effect of peptide vaccines2019
- Author(s)
  Kumai T, Sultan H, Harabuchi Y, Celis E
- Organizer
  American Assiciation for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫67症例の臨床学的検討2019
- Author(s)
  高原　幹, 熊井琢美, 岸部　幹, 片田彰博, 林　達哉, 原渕保明
- Organizer
  第16回EBウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Cancer Immunity Cycleと化学療法2019
- Author(s)
  原渕翔平, 大原賢三, 野﨑　結, 熊井琢美, 長門利純, 林　達哉, 小林博也, 原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] A clinical and pathological characterization of Epstein-Barr virus positive methotrexate-associated lymphoproliferative disorders for seven cases2018
- Author(s)
  Araki D, Kumai T, Nagato T, Kishibe K, Takahara M, Katada A, Hayashi T, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫における免疫抑制サイトカインの検討2018
- Author(s)
  熊井琢美、長門利純、岸部幹、高原幹、青木直子、及川賢輔、林達哉、小林博也、原渕保明
- Organizer
  第15回EBウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Optimization of peptide vaccines to induce robust antitumor CD4 T-cell responses2018
- Author(s)
  Kumai, T.//Sultan, H.//Kobayashi, H.//Harabuchi, Y.//Celis, E.
- Organizer
  American Association for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223
[Presentation] The identification of extranodal NK/T cell lymphoma, nasal type-associated antigen for helper T cell-based immunotherapy2018
- Author(s)
  Kumai T.//Komatsuda, H.// Araki, D.//Nagato, T.//Kishibe, K.//Takahara, M.//Hayashi, T.//Harabuchi, Y.
- Organizer
  International Conference on EBV & KSHV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223
[Presentation] The identification of extranodal NK/T cell lymphoma, nasal type-associated antigen for helper T cell-based immunotherapy2018
- Author(s)
  Kumai T, Komatsuda H, Araki D, Nagato T, Kishibe K, Takahara M, Hayashi T, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] EBウイルス陽性鼻性NK/T細胞リンパ腫に対するペプチドワクチン療法の開発2018
- Author(s)
  原渕翔平、熊井琢美、長門利純、林達哉、原渕保明
- Organizer
  第57回日本鼻科学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] ヘルパーペプチドワクチンの実用化に向けたアジュバントの開発2018
- Author(s)
  熊井琢美//大原賢三//野崎　結//長門利純//林達哉//小林博也//原渕保明
- Organizer
  日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-16K20223
[Presentation] Expression of programmed death-ligand 1 in nasal natural killer/T-cell lymphoma2018
- Author(s)
  Nagato t, Ohkuri T, Ohara K, Nozaki Y, Kishibe K, Takahara M, Kumai T, Araki D, Komabayashi H, Kobayashi H, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Optimization of peptide vaccines to induce robust antitumor CD4 T-cell responses2018
- Author(s)
  Kumai T.//Sultan, H.//Kobayashi, H.//Harabuchi, Y.//Celis, E.
- Organizer
  American Association for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223
[Presentation] Expression and function of Epstein-Barr virus-encoded microRNAs in nasal natural killer/T-cell lymphoma2018
- Author(s)
  Kishibe K, Komabayashi Y, Kumai T, Nagato T, Takahara M, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Antitumor responses by HER-3-reactive CD4 helper T cells combined with HER inhibitor in vitro2017
- Author(s)
  Takumi Kumai, Tatsuya Hayashi, Hiroya Kobayashi, Yasuaki Harabuchi
- Organizer
  The International Federation of ORL Societies (IFOS) 2017
- Place of Presentation
  パリ(フランス)
- Year and Date
  2017-06-24
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] EBウイルス陽性鼻性NK/T細胞リンパ腫にたいするペプチドワクチン療法の開発2017
- Author(s)
  熊井琢美, 長門利純, 林達哉, 小林博也, 原渕保明
- Organizer
  第65回日本ウイルス学会
- Place of Presentation
  大阪
- Year and Date
  2017-10-25
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] The identification of nasal NK/T-cell lymphoma-associated antigens for helper T cell-based immunotherapy2017
- Author(s)
  Takumi Kumai, Toshihiro Nagato, Miki Takahara, Akihiro Katada, Tatsuya Hayashi, Yasuaki Harabuchi
- Organizer
  53rd Korean Rhinologic Society Annual Congress
- Place of Presentation
  ソウル(韓国)
- Year and Date
  2017-03-12
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] The identification of nasal NK/T-cell lymphoma-associated antigens for helper T cell-based immunotherapy2017
- Author(s)
  Takumi Kumai, Toshihiro Nagato, Miki Takahara, Akihiro Katada, Tatsuya Hayashi, Yasuaki Harabuchi
- Organizer
  53rd Korean Rhinologic Society Annual Congress
- Place of Presentation
  ソウル、韓国
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223
[Presentation] Antitumor responses by HER-3-reactive CD4 helper T cells combined with HER inhibitor in vitro2017
- Author(s)
  Kumai, T.//Hayashi, T.//Kobayashi, H.//Harabuchi, Y.
- Organizer
  The International Federation of ORL Societies (IFOS) 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223
[Presentation] EBウイルス陽性鼻性NK/T細胞リンパ腫にたいするペプチドワクチン療法の開発2017
- Author(s)
  熊井琢美//長門利純//林　達哉/小林博也//原渕保明
- Organizer
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16K20223
[Presentation] The identification of nasal NK/T-cell lymphoma-associated antigens for helper T cell-based immunotherapy2017
- Author(s)
  Kumai, T.//Nagato, T,//Takahara, M.//Katada, A.//,Hayashi, T.//Harabuchi, Y.
- Organizer
  53rd Korean Rhinologic Society Annual Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20223
[Presentation] HER-3標的ヘルパーCD4 T細胞による抗腫瘍効果と HER 阻害薬併用による相乗効果の検討2016
- Author(s)
  熊井琢美, 大原賢三, 平田結, 大栗敬幸, 小坂朱, 長門利純, 石橋佳, 及川賢輔, 原渕保明, 小林博也
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] 鼻性NK/T細胞リンパ腫におけるc-Metを標的とした免疫療法の開発2016
- Author(s)
  熊井琢美, 大原賢三, 長門利純, 高原幹, 片田彰博, 林達哉, 小林博也, 原渕保明
- Organizer
  第117回日本耳鼻咽喉科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] HER-3由来CD4エピトープの同定およびHER阻害薬との併用について2016
- Author(s)
  熊井琢美, 石橋佳, 大栗敬幸, 及川賢輔, 青木直子, 原渕保明, 小林博也
- Organizer
  第105回日本病理学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] EGFR阻害薬による抗腫瘍免疫への影響について2015
- Author(s)
  熊井琢美, 大栗敬幸, 小坂朱, 長門利純, 石橋佳, 大原賢三, 平田結, 及川賢輔, 原渕保明, 小林博也
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] EGFR阻害薬によって腫瘍から放出される抑制性サイトカインは抗腫瘍免疫を低したさせうる2015
- Author(s)
  熊井琢美, 原渕保明, 小林博也
- Organizer
  第104回日本病理学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] EGFR反応性CD4陽性ヘルパーT細胞クローンの樹立及び EGFR阻害薬のアジュバントとしての有用性2013
- Author(s)
  熊井琢美
- Organizer
  日本耳鼻咽喉科学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] C-C chemokine receptor 4 is a remarkable molecule for novel targeted therapy against nasal natural killer/T-cell lymphoma
- Author(s)
  Toshihiro Nagato, Takumi Kumai, Hiroya Kobayashi, Yuki Komabayashi, Seigo Ueda, Kan Kishibe, Miki Takahara, Yasuaki Harabuchi
- Organizer
  16th International Symposium on EBV
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2014-07-16 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-24390385
[Presentation] 腫瘍免疫におけるアジュバントとしての EGFR阻害薬の有用性
- Author(s)
  熊井琢美
- Organizer
  第31回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  倉敷
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] 鼻性NK/T 細胞リンパ腫における新規c-MetヘルパT細胞エピトープの探索
- Author(s)
  熊井琢美
- Organizer
  第46回北海道病理談話会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-24390385
[Presentation] EGFR inhibition augments anti-tumor immune responses by HER family-specific human CD4 helper T cells in vitro
- Author(s)
  熊井琢美
- Organizer
  AACR annual meeting 2013
- Place of Presentation
  Washington, D.C.
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] EGFR inhibition augments anti-tumor immune responses by HER family-specific human CD4 helper T cells in vitro
- Author(s)
  熊井琢美
- Organizer
  AACR annual meeting 2013
- Place of Presentation
  Washington, D.C.
- Data Source
  KAKENHI-PROJECT-24791735
[Presentation] EGFR inhibition augments anti-tumor immune responses by HER family-specific human CD4 helper T cells
- Author(s)
  熊井琢美
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791735

1. HARABUCHI Yasuaki (80208686)

# of Collaborated Projects: 5 results

# of Collaborated Products: 45 results
2. KOBAYASHI Hiroya (90280867)

# of Collaborated Projects: 5 results

# of Collaborated Products: 33 results
3. TAKAHARA Miki (50322904)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
4. KISHIBE Kan (80447101)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
5. NAGATO Toshihiro (80431419)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
6. 大栗敬幸 (70564061)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
7. 大原賢三 (20596308)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
8. UEDA Seigo (90447102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. KOMABAYASHI Yuki (40548864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 野中雅人 (30835286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 服部ユカリ (00272899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 牧野志津 (30814503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 寒風澤知明 (40936332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kumai Takumi 熊井 琢美

KUMAI Takumi 熊井 琢美

Research Projects

Research Products

Co-Researchers

扁桃における糖鎖不全IgAとT細胞サブセットを中心としたIgA腎症の病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

鼻性NK/T細胞リンパ腫を治癒に導く複合的免疫療法の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

頭頸部癌に対する免疫チェックポイント阻害薬のバイオマーカー探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高齢頭頸部癌患者の化学放射線療法による有害事象に対する口腔内評価ツールの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developing novel immunotherapy against nasal NK/T cell lymphoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Combination of molecular-targeted therapy with peptide vaccinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A foundational study for targeted therapy against EB virus and tumor growth factor in nasal NK/T-cell lymphoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HER family targeted immunotherapy against head and neck squamous cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A critical role of STING-triggered tumor-migrating neutrophils for anti-tumor effect of intratumoral cGAMP treatment2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphorylated vimentin as an immunotherapeutic target against metastatic colorectal cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intratumoral STING activations overcome negative impact of cisplatin on antitumor immunity by inflaming tumor microenvironment in squamous cell carcinoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma.2019

Author(s)

Kumai Takumi 熊井琢美

KUMAI Takumi 熊井琢美