Okuri Takayuki 大栗敬幸

… Alternative Names

Ohkuri Takayuki 大栗敬幸

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Researcher Number	70564061
Other IDs	https://orcid.org/0000-0002-6889-7809
Affiliation (Current)	2025: 旭川医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 旭川医科大学, 医学部, 准教授 2017 – 2018: 旭川医科大学, 医学部, 講師 2016: 旭川医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related / Human pathology Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Basic Section 49020:Human pathology-related / Experimental pathology / Human pathology
Keywords	Principal Investigator 腫瘍免疫 / 単球由来樹状細胞 / がん所属リンパ節 / エピジェネティック / がんの免疫逃避機構 / ワクチン / がん免疫療法 / がん免疫 / がんワクチン / がん免疫治療 … More / ステルスがん抗原 / I型IFN / マクロファージ / macrophages / STING … More Except Principal Investigator 鼻性NK/T細胞リンパ腫 / NK/T細胞リンパ腫 / 腫瘍免疫 / cGAS/STING/I型IFN / 癌免疫微小環境 / STING / cGAMP / I型インターフェロン / ワクチン / ペプチド / 免疫療法 / 免疫抑制 / 腫瘍抗原 / EBウイルス / ペプチドワクチン / 免疫チェックポイント / がん / 感染症 / 抗原特異的T細胞 / 抗原提示能 / サイトカイン産生 / 神経ペプチド受容体 / 神経ペプチド / 樹状細胞 / グリオーマ / 免疫監視機構 / 免疫逃避機構 / cancer vaccines Less

がん免疫治療の奏効率向上を目指した腫瘍微小環境内の良質な炎症状態の誘導戦略Principal Investigator
- Principal Investigator
  
  大栗敬幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Asahikawa Medical College
cGAS/STING/I型IFN経路を基軸とした癌免疫微小環境のホット化治療戦略
- Principal Investigator
  
  小林博也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Asahikawa Medical College
Establishment of novel immunotherapy against nasal NK/T cell lymphoma
- Principal Investigator
  
  Harabuchi Yasuaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Asahikawa Medical College
Study for establishing new cancer immunotherapy targeting tumor escape from imune surveillancePrincipal Investigator
- Principal Investigator
  
  Ohkuri Takayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Asahikawa Medical College
Developing novel immunotherapy against nasal NK/T cell lymphoma
- Principal Investigator
  
  Harabuchi Yasuaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Asahikawa Medical College
Study for mechanism of STING-mediated inflammation in tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  Ohkuri Takayuki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Asahikawa Medical College
Analysis of stealth antigens for developing tumor immunotherapy
- Principal Investigator
  
  Kobayashi Hiroya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Asahikawa Medical College
Studies of neuropeptide signaling on functional regulation of dendritic cells and the pathogenesis of cancer and inflammatory diseases
- Principal Investigator
  
  Kitamura Hidemitsu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015

All Journal Article Presentation Book Patent

[Book] 腫瘍内科2021
- Author(s)
  大栗敬幸、小坂朱、小林博也
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-20K07367
[Journal Article] Soluble CD27 as a predictive biomarker for intra-tumoral CD70/CD27 interaction in nasopharyngeal carcinoma2024
- Author(s)
  Nagato T, Komatsuda H, Hayashi R, Takahara M, Ujiie N, Kosaka A, Ohkuri T, Oikawa K, Sato R, Wakisaka R, Kono M, Yamaki H, Ohara K, Kumai T, Kishibe K, Katada A, Hayashi T, Kobayashi H
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 4 Pages: 1073-1084
- DOI
  10.1111/cas.16079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09599, KAKENHI-PROJECT-21H03082
[Journal Article] Expression of soluble CD27 in extranodal natural killer/T-cell lymphoma, nasal type: potential as a biomarker for diagnosis and CD27/CD70-targeted therapy2023
- Author(s)
  Nagato T, Komatsuda H, Hayashi R, Takahara M, Kishibe K, Yasuda S, Yajima Y, Kosaka A, Ohkuri T, Oikawa K, Harabuchi S, Kono M, Yamaki H, Wakisaka R, Hirata-Nozaki Y, Ohara K, Kumai T, Katada A, Hayashi T, Harabuchi Y, Kobayashi H
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 72 Issue: 7 Pages: 2087-2098
- DOI
  10.1007/s00262-023-03394-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09599, KAKENHI-PROJECT-21H03082
[Journal Article] Mitogen‐activated protein kinase inhibition augments the T cell response against HOXB7‐expressing tumor through human leukocyte antigen upregulation2022
- Author(s)
  Komatsuda Hiroki、Wakisaka Risa、Kono Michihisa、Kumai Takumi、Hayashi Ryusuke、Yamaki Hidekiyo、Sato Ryosuke、Nagato Toshihiro、Ohkuri Takayuki、Kosaka Akemi、Ohara Kenzo、Takahara Miki、Katada Akihiro、Kobayashi Hiroya
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 2 Pages: 399-409
- DOI
  10.1111/cas.15619
- Data Source
  KAKENHI-PROJECT-21H03082, KAKENHI-PROJECT-20K09724
[Journal Article] Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery2021
- Author(s)
  Kono Michihisa、Kumai Takumi、Hayashi Ryusuke、Yamaki Hidekiyo、Komatsuda Hiroki、Wakisaka Risa、Nagato Toshihiro、Ohkuri Takayuki、Kosaka Akemi、Ohara Kenzo、Kishibe Kan、Takahara Miki、Katada Akihiro、Hayashi Tatsuya、Celis Esteban、Kobayashi Hiroya、Harabuchi Yasuaki
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: epub Issue: 12 Pages: 3421-3434
- DOI
  10.1007/s00262-021-02940-5
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] A critical role of STING-triggered tumor-migrating neutrophils for anti-tumor effect of intratumoral cGAMP treatment2021
- Author(s)
  Nagata Marino、Kosaka Akemi、Yajima Yuki、Yasuda Syunsuke、Ohara Mizuho、Ohara Kenzo、Harabuchi Shohei、Hayashi Ryusuke、Funakoshi Hiroshi、Ueda Jun、Kumai Takumi、Nagato Toshihiro、Oikawa Kensuke、Harabuchi Yasuaki、Esteban Celis、Ohkuri Takayuki、Kobayashi Hiroya
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: epub Issue: 8 Pages: 2301-2312
- DOI
  10.1007/s00262-021-02864-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-19K06452
[Journal Article] A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy2021
- Author(s)
  Kosaka Akemi,Yajima Yuki,Hatayama Mayumi,Ikuta Katsuya,Sasaki Takaaki,Hirai Noriko,Ohkuri Takayuki
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 7 Pages: 2705-2713
- DOI
  10.1111/cas.14973
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15300, KAKENHI-PROJECT-20K07367
[Journal Article] Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma2020
- Author(s)
  Hayashi Ryusuke、Nagato Toshihiro、Kumai Takumi、Ohara Kenzo、Ohara Mizuho、Ohkuri Takayuki、Hirata-Nozaki Yui、Kosaka Akemi、Yasuda Syunsuke、Oikawa Kensuke、Kono Michihisa、Kishibe Kan、Takahara Miki、Katada Akihiro、Hayashi Tatsuya、Celis Esteban、Harabuchi Yasuaki、Kobayashi Hiroya et al
- Journal Title
  
  OncoImmunology
  
  Volume: 10 Issue: 1 Pages: 1856545-1856545
- DOI
  10.1080/2162402x.2020.1856545
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Phosphorylated vimentin as an immunotherapeutic target against metastatic colorectal cancer.2019
- Author(s)
  Ohara M, Ohara K, Kumai T, Ohkuri T, Nagato T, Hirata-Nozaki Y, Kosaka A, Nagata M, Hayashi R, Harabuchi S, Yajima Y, Oikawa K, Harabuchi Y, Sumi Y, Furukawa H, Kobayashi H.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: ePub Issue: 6 Pages: 989-999
- DOI
  10.1007/s00262-020-02524-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-19K07452
[Journal Article] PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma.2019
- Author(s)
  Hirata-Nozaki Y, Ohkuri T, Ohara K, Kumai T, Nagata M, Harabuchi S, Kosaka A, Nagato T, Ishibashi K, Oikawa K, Aoki N, Ohara M, Harabuchi Y, Uno Y, Takei H, Celis E, Kobayashi H.
- Journal Title
  
  J Transl Med.
  
  Volume: 17 Issue: 1
- DOI
  10.1186/s12967-019-1957-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Intratumoral STING activations overcome negative impact of cisplatin on antitumor immunity by inflaming tumor microenvironment in squamous cell carcinoma.2019
- Author(s)
  Harabuchi S, Kosaka A, Yajima Y, Nagata M, Hayashi R, Kumai T, Ohara K, Nagato T, Oikawa K, Ohara M, Harabuchi Y, Ohkuri T, Kobayashi H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 522 Issue: 2 Pages: 408-414
- DOI
  10.1016/j.bbrc.2019.11.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-19K18791
[Journal Article] Cyclin-dependent kinase 1 and survivin as potential therapeutic targets against nasal natural killer/T-cell lymphoma2019
- Author(s)
  Nagato Toshihiro、Ueda Seigo、Takahara Miki、Kishibe Kan、Komabayashi Yuki、Kumai Takumi、Ohara Kenzo、Hirata-Nozaki Yui、Harabuchi Shohei、Hayashi Ryusuke、Ohkuri Takayuki、Bernasconi Michele、Nadal David、Kobayashi Hiroya、Harabuchi Yasuaki
- Journal Title
  
  Laboratory Investigation
  
  Volume: 99 Issue: 5 Pages: 612-624
- DOI
  10.1038/s41374-018-0182-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Effects of STING stimulation on macrophages: STING agonists polarize into "classically" or "alternatively" activated macrophages?2018
- Author(s)
  Ohkuri T, Kosaka A, Nagato T, Kobayashi H.
- Journal Title
  
  Hum Vaccin Immunother
  
  Volume: 14(2) Issue: 2 Pages: 285-287
- DOI
  10.1080/21645515.2017.1395995
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19070
[Journal Article] 鼻性NK/T細胞リンパ腫に対する革新的免疫療法の開発2018
- Author(s)
  長門利純、熊井琢美,、高原幹、大栗敬幸、小林博也、Celis Esteban、原渕保明
- Journal Title
  
  耳鼻咽喉科免疫アレルギー
  
  Volume: 36 Pages: 15-22
- NAID
  130006619256
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site.2017
- Author(s)
  Ohkuri T, Kosaka A, Ishibashi K, Kumai T, Hirata Y, Ohara K, Nagato T, Oikawa K, Aoki N, Harabuchi Y, Celis E, Kobayashi H.
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: - Issue: 6 Pages: 705-716
- DOI
  10.1007/s00262-017-1975-1
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19070, KAKENHI-PROJECT-16K19071
[Journal Article] Intratumoral injection of IFN-β induces chemokine production in melanoma and augments the therapeutic efficacy of anti-PD-L1 mAb.2017
- Author(s)
  Uehara J, Ohkuri T, Kosaka A, Ishibashi K, Hirata Y, Ohara K, Nagato T, Oikawa K, Aoki N, Harabuchi Y, Ishida-Yamamoto A, Kobayashi H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 490(2) Issue: 2 Pages: 521-527
- DOI
  10.1016/j.bbrc.2017.06.072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19070
[Patent] がん抗原ペプチド2018
- Inventor(s)
  小林博也、大栗敬幸、小坂朱
- Industrial Property Rights Holder
  小林博也、大栗敬幸、小坂朱
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-024972
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K15244
[Patent] がん抗原ペプチド2017
- Inventor(s)
  大栗敬幸、小林博也、小坂朱
- Industrial Property Rights Holder
  大栗敬幸、小林博也、小坂朱
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-072183
- Filing Date
  2017-03-18
- Data Source
  KAKENHI-PROJECT-16K15244
[Presentation] 腫瘍微小環境の炎症誘導により所属リンパ節に遊走する単球由来樹状細胞の性状解析2023
- Author(s)
  大栗敬幸
- Organizer
  第27回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K27383
[Presentation] 担がんマウスの所属リンパ節におけるCD11b+Ly6Chigh単球由来樹状細胞の機能解析2023
- Author(s)
  大栗敬幸
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K27383
[Presentation] SPESP1はエピジェネティックに発現抑制を受けるステルスがん抗原としてがん免疫の標的抗原になりうる2021
- Author(s)
  大栗敬幸、小坂朱、矢島優己、安田俊輔、小松田浩樹、長門利純、及川賢輔、小林博也
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-20K07367
[Presentation] エピジェネティックに発現抑制を受けるステルスがん抗原SPESP1を標的とした新しいがん免疫療法の開発2021
- Author(s)
  大栗敬幸、小坂朱、矢島優己、安田俊輔、長門利純、及川賢輔、小林博也
- Organizer
  日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-20K07367
[Presentation] マウス扁平上皮癌モデルを用いた、化学療法とSTING活性化療法の併用に関する基礎研究2019
- Author(s)
  原渕翔平, 大栗敬幸, 小坂　朱, 永田真莉乃, 林　隆介, 大原賢三, 大原みずほ, 長門利純, 及川賢輔, 小林博也
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 癌特異的な翻訳後修飾を受けたp53タンパク質は特異的T細胞応答を惹起する2019
- Author(s)
  大原賢三, 大栗敬幸, 長門利純, 小林博也
- Organizer
  第23回日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 頭頸部悪性腫瘍におけるCD74の発現2019
- Author(s)
  林　隆介, 長門利純, 永田真莉乃, 原渕翔平, 大原賢三, 大原みずほ, 小坂朱, 大栗敬幸, 及川賢輔, 小林博也
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫および上咽頭癌におけるCD74とMIFの発現2019
- Author(s)
  熊井琢美, 林　隆介, 長門利純, 原渕翔平, 岸部　幹, 高原　幹, 永田真莉乃, 矢島優己, 小坂　朱, 大栗敬幸, 及川賢輔, 小林博也, 原渕保明
- Organizer
  第16回EBウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Expression of cell surface CD74 and macrophage migration inhibitory factor in malignant tumors of head and neck region2019
- Author(s)
  Hayashi R, Nagato T, Kumai T, Nagata M, Harabuchi S, Yajima Y, Kosaka A, Ohkuri T, Oikawa K, Kishibe K, Takahara M, Harabuchi Y, Kobayashi H
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫におけるCDK1とサバイビンの発現2018
- Author(s)
  長門利純、大原賢三、原渕翔平、林隆介、大栗敬幸、永田真莉乃、大原みずほ、小坂朱、青木直子、及川賢輔、原渕保明、小林博也
- Organizer
  第51回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Expression of programmed death-ligand 1 in nasal natural killer/T-cell lymphoma2018
- Author(s)
  Nagato t, Ohkuri T, Ohara K, Nozaki Y, Kishibe K, Takahara M, Kumai T, Araki D, Komabayashi H, Kobayashi H, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Intratumoral STING stimulation recruits M1 macrophage in the tumor via NF-kB/TLR4 pathway to trigger anti!tumor immunity2017
- Author(s)
  大栗敬幸
- Organizer
  第21回がん免疫学会
- Data Source
  KAKENHI-PROJECT-16K19070
[Presentation] Intratumoral cGAMP injection recruits M1 macrophage in the tumor microenvironment via NF-kB/TLR4 pathway to trigger anti-tumor immunity2017
- Author(s)
  大栗敬幸
- Organizer
  The 36th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19070
[Presentation] STING-mediated inflammation in tumor site2017
- Author(s)
  大栗敬幸
- Organizer
  Oncology Focus Symposium in Sapporo
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19070
[Presentation] A novel mechanism for activating Type-1 immunity by neuropeptide signalings through NK1R and NK2R in tumor microenvironments2015
- Author(s)
  Takayuki Ohkuri, Junya Ohtake, Shun Kaneumi, Hidemitsu Kitamura, Hiroya Kobayashi
- Organizer
  The 10th International Symposium of the Institute Network “Towards the next generation research for cancer and immunology”
- Place of Presentation
  北海道大学医学部学友会館「フラテ」（北海道・札幌市）
- Year and Date
  2015-07-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08416

1. Kobayashi Hiroya (90280867)

# of Collaborated Projects: 6 results

# of Collaborated Products: 17 results
2. 長門利純 (80431419)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
3. 小坂朱 (40561030)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. Harabuchi Yasuaki (80208686)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. 熊井琢美 (00596306)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
6. 高原幹 (50322904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. 岸部幹 (80447101)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. 大原賢三 (20596308)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
9. Kitamura Hidemitsu (40360531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 平井理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okuri Takayuki 大栗 敬幸

Ohkuri Takayuki 大栗 敬幸

Research Projects

Research Products

Co-Researchers

がん免疫治療の奏効率向上を目指した腫瘍微小環境内の良質な炎症状態の誘導戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

cGAS/STING/I型IFN経路を基軸とした癌免疫微小環境のホット化治療戦略

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of novel immunotherapy against nasal NK/T cell lymphoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study for establishing new cancer immunotherapy targeting tumor escape from imune surveillancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developing novel immunotherapy against nasal NK/T cell lymphoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study for mechanism of STING-mediated inflammation in tumor microenvironmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of stealth antigens for developing tumor immunotherapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies of neuropeptide signaling on functional regulation of dendritic cells and the pathogenesis of cancer and inflammatory diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 腫瘍内科2021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Soluble CD27 as a predictive biomarker for intra-tumoral CD70/CD27 interaction in nasopharyngeal carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of soluble CD27 in extranodal natural killer/T-cell lymphoma, nasal type: potential as a biomarker for diagnosis and CD27/CD70-targeted therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitogen‐activated protein kinase inhibition augments the T cell response against HOXB7‐expressing tumor through human leukocyte antigen upregulation2022

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[Journal Article] Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery2021

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[Journal Article] A critical role of STING-triggered tumor-migrating neutrophils for anti-tumor effect of intratumoral cGAMP treatment2021

Author(s)

Okuri Takayuki 大栗敬幸

Ohkuri Takayuki 大栗敬幸