Kohsaka Shinji 高阪真路

Researcher Number	00627119
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, 分野長
Affiliation (based on the past Project Information) *help	2021 – 2024: 国立研究開発法人国立がん研究センター, 研究所, 分野長 2020 – 2021: 国立研究開発法人国立がん研究センター, 研究所, ユニット長 2018 – 2019: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員 2016 – 2017: 東京大学, 大学院医学系研究科(医学部), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related Except Principal Investigator Basic Section 49020:Human pathology-related / Orthopaedic surgery / Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 56020:Orthopedics-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator ハイスループット機能解析 / がん遺伝子 / 薬剤耐性 / ゲノム医学 / バイオマテリアル / 機能解析 / 融合遺伝子 / 肉腫 Except Principal Investigator 骨軟部腫瘍 / 骨軟部肉腫 … More / 融合遺伝子 / 個別化医療 / 免疫応答 / チロシンキナーゼ / エンハンサー / トランスクリプトーム解析 / CAGE / 肺癌 / 遺伝子 / 肺がん / トランスクリプトーム / がん / 分子標的治療 / プロテオミクス解析 / 発現解析 / 小児腫瘍学 / 紡錘形細胞がん / 未分化がん / 肉腫様がん / 高機能ゲル / 多様性 / ポリマーハイドロゲル / バイオマテリアル / 薬剤耐性 / リプログラミング / ハイドロゲル / がん幹細胞 / チロシンキナーゼ阻害剤 / プレシジョンメディシン / がんクリニカルシークエンス / 微小環境 / 小胞体ストレス / 転写変異体 / TK遺伝子変異 / TK遺伝子転写変異体 / tyrosine Kinase / 遺伝子変異体 / 遺伝子転写変異体 / 軟部肉腫 / 整形外科 / ゲノム / 癌 / がんゲノム / ゲノム解析 / 肉腫 Less

Construction of the sarcomatoid carcinoma concept and pathological investigation
- Principal Investigator
  
  小嶋基寛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  National Cancer Center Japan
小児がんにおける遺伝子発現解析を基盤とした治療標的候補同程と臨床応用に向けた研究
- Principal Investigator
  
  田尾佳代子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Cancer Center Japan
Development of personalized medicine for lung cancer using next-generation transcriptome
- Principal Investigator
  
  林大久生
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Juntendo University
Comprehensive search for mechanisms of resistance to molecularly targeted therapiesPrincipal Investigator
- Principal Investigator
  
  Kohsaka Shinji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Cancer Center Japan
Development of novel treatment based on functional analysis of endoplasmic reticulum stress in bone and soft tissue sarcoma
- Principal Investigator
  
  Suehara Yoshiyuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  National Cancer Center Japan
  Juntendo University
Functional analysis and discovery of molecular targets in bone and soft tissue sarcoma based on cancer clinical sequence
- Principal Investigator
  
  Suehara Yoshiyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
Reprogramming of cancer stem cells by high-function hydrogels creates basis to establish novel cancer therapy
- Principal Investigator
  
  Tanaka Shinya
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hokkaido University
Comprehensive investigation of tumorigenesis mechanism induced by sarcoma-related fusion genesPrincipal Investigator
- Principal Investigator
  
  Kohsaka Shinji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cancer Center Japan
Identification of diagnostic biomarker and novel fusion genes of bone and soft tissue sarcoma
- Principal Investigator
  
  Matsuda Koichi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Screening for alternative transcription initiation of tyrosine kinase genes in bone and soft tissue tumors
- Principal Investigator
  
  Suehara Yoshiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 Other

All Journal Article Presentation Book Other

[Book] がんゲノム病理学2021
- Author(s)
  高阪真路
- Total Pages
  234
- Publisher
  文光堂
- ISBN
  9784830604850
- Data Source
  KAKENHI-PROJECT-21H02795
[Book] C-CAT調査結果の読み方. がんゲノム医療遺伝子パネル検査実践ガイド2020
- Author(s)
  高阪真路
- Total Pages
  252
- Publisher
  医学書院
- ISBN
  9784260042468
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] BIO Clinica 2019年 8月臨時増刊号 VUS解釈のためのハイスループット機能解析法2019
- Author(s)
  高阪真路
- Total Pages
  100
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] Precision Medicine　2019年2月号　がんクリニカルシークエンス検査の開発と臨床応用2019
- Author(s)
  高阪真路, 辰野健二, 織田克利
- Total Pages
  102
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] 病理と臨床 2019年10月号シングルセル解析遺伝子解析2019
- Author(s)
  高阪真路
- Total Pages
  112
- Publisher
  文光堂
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] 医学のあゆみがん研究10か年戦略の成果と課題プレシジョンメディシンの実現に向けた意義不明変異の解釈2019
- Author(s)
  高阪真路
- Total Pages
  272
- Publisher
  医歯薬出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] 特集　がんゲノム医療・Precision Medicineの展開と諸問題2018
- Author(s)
  高阪真路, 辰野健二, 織田克利
- Total Pages
  132
- Publisher
  科学評論社
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] 実験医学増刊 Vol.36 No.15　動き始めた　がんゲノム医療2018
- Author(s)
  高阪真路
- Total Pages
  243
- Publisher
  羊土社
- ISBN
  9784758103732
- Data Source
  KAKENHI-PROJECT-18H02677
[Journal Article] The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma2024
- Author(s)
  Shirai Y, Ueno T, Kojima S, Ikeuchi H, Kitada R, Koyama T, Takahashi F, Takahashi K, Ichimura K, Yoshida A, Sugino H, Mano H, Narita Y, Takahashi M, Kohsaka S
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 167 Issue: 1 Pages: 75-88
- DOI
  10.1007/s11060-024-04563-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795
[Journal Article] Analysis of quality metrics in comprehensive cancer genomic profiling using a dual DNA-RNA panel2024
- Author(s)
  Watanabe K, Kohsaka S, Tatsuno K, Shinozaki-Ushiku A, Isago H, Kage H, Ushiku T, Aburatani H, Mano H, Oda K
- Journal Title
  
  Pract Lab Med
  
  Volume: 39 Pages: 368-368
- DOI
  10.1016/j.plabm.2024.e00368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03074
[Journal Article] Inflammatory Rhabdomyoblastic Tumor: Clinicopathologic and Molecular Analysis of 13 Cases2024
- Author(s)
  Odate T, Satomi K, Kubo T, Matsushita Y, Ueno T, Kurose A, Shomori K, Nakai T, Watanabe R, Segawa K, Ohshika S, Miyake N, Kudo S, Shimoi T, Kobayashi E, Komiyama M, Yoshimoto S, Nakatani F, Kawai, A, Yatabe Y, Kohsaka S, Ichimura K, Ichikawa H, Yoshida Akihiko
- Journal Title
  
  Modern Pathology
  
  Volume: 37 Issue: 1 Pages: 100359-100359
- DOI
  10.1016/j.modpat.2023.100359
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06919, KAKENHI-PROJECT-22K06951, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-23K27389
[Journal Article] Dramatic response to entrectinib in a patient with malignant peripheral nerve sheath tumor harboring novel SNRNP70-NTRK3 fusion gene2023
- Author(s)
  Kobayashi H, Makise N, Shinozaki-Ushiku A, Zhang L, Ishibashi Y, Ikegami M, Tsuda Y, Kohsaka S, Ushiku T, Oda K, Miyagawa K, Aburatani H, Mano H, Tanaka S.
- Journal Title
  
  Genes Chromosomes Cancer.
  
  Volume: 62 Issue: 1 Pages: 47-51
- DOI
  10.1002/gcc.23089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16648, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-20K16167, KAKENHI-PROJECT-21H03074
[Journal Article] Molecular pathology quality control in Southeast Asia: Results of a multiregional quality assurance study from MASTER KEY Asia2023
- Author(s)
  Okuma Hitomi Sumiyoshi、Yoshida Hiroshi、Kobayashi Yoshihisa、Arakaki Motoko、Mizoguchi Chiharu、Inagaki Lina、Voon Pei Jye、Malik Bin Ismail Adam、Fen Soo Hoo Hwoei、Yusak Suhana、Severino B. Imasa Marcelo、Nguyen Huy Thinh、Thai Anh Tu、Kohsaka Shinji、Mano Hiroyuki、Yonemori Kan、Nakamura Kenichi、Yatabe Yasushi
- Journal Title
  
  Cancer Science
  
  Volume: in press Issue: 6 Pages: 2664-2673
- DOI
  10.1111/cas.15790
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-23K18323, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-23K27389, KAKENHI-PROJECT-23K27690
[Journal Article] Promoter swapping of truncated PDGFRB drives Ph-like acute lymphoblastic leukemia2023
- Author(s)
  Miyazaki Bunpei、Ueno Toshihide、Sugiyama Masanaka、Kojima Shinya、Arakawa Ayumu、Tao Kayoko、Tanimura Kazuki、Shiraishi Kouya、Yagishita Shigehiro、Kohsaka Shinji、Kato Mamoru、Kiyokawa Nobutaka、Goto Yasushi、Yatabe Yasushi、Hamada Akinobu、Mano Hiroyuki、Ogawa Chitose、Tanaka Yosuke
- Journal Title
  
  npj Precision Oncology
  
  Volume: 7 Issue: 1 Pages: 132-132
- DOI
  10.1038/s41698-023-00485-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-23K27389
[Journal Article] Extensive analysis of 59 sarcoma‐related fusion genes identified pazopanib as a potential inhibitor to <scp><i>COL1A1‐PDGFB</i></scp> fusion gene2023
- Author(s)
  Hirose Takeshi、Ikegami Masachika、Kojima Shinya、Yoshida Akihiko、Endo Makoto、Shimada Eijiro、Kanahori Masaya、Oyama Ryunosuke、Matsumoto Yoshihiro、Nakashima Yasuharu、Kawai Akira、Mano Hiroyuki、Kohsaka Shinji
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 10 Pages: 4089-4100
- DOI
  10.1111/cas.15915
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08700, KAKENHI-PROJECT-22K15571, KAKENHI-PROJECT-21H02795
[Journal Article] Clinical Activity and Exploratory Resistance Mechanism of Milademetan, an MDM2 Inhibitor, in Intimal Sarcoma with <i>MDM2</i> Amplification: An Open-Label Phase Ib/II Study2023
- Author(s)
  Koyama Takafumi、Shimizu Toshio、Kojima Yuki、Sudo Kazuki、Okuma Hitomi Sumiyoshi、Shimoi Tatsunori、Ichikawa Hitoshi、Kohsaka Shinji、Sadachi Ryo、Hirakawa Akihiro、Yoshida Akihiko、Ando Reiko Makihara、Ueno Toshihide、Yanagaki Mitsuru、Matsui Naoko、Nakamura Kenichi、Yamamoto Noboru、Yonemori Kan
- Journal Title
  
  Cancer Discovery
  
  Volume: 13 Issue: 8 Pages: 1814-1825
- DOI
  10.1158/2159-8290.cd-23-0419
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15614, KAKENHI-PROJECT-20K11703, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03062
[Journal Article] Expression of paired box 9 defines an aggressive subset of lung adenocarcinoma preferentially occurring in smokers2023
- Author(s)
  Hayashi Takuo、Kishi Monami、Takamochi Kazuya、Hosoya Masaki、Kohsaka Shinji、Kishikawa Satsuki、Ura Ayako、Sano Kei、Sasahara Noriko、Suehara Yoshiyuki、Takahashi Fumiyuki、Saito Tsuyoshi、Suzuki Kenji、Yao Takashi、the Tokyo Metropolitan Innovative Oncology Research Group (TMIG)
- Journal Title
  
  Histopathology
  
  Volume: 82 Issue: 5 Pages: 672-683
- DOI
  10.1111/his.14853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-22K15416, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-21H02795
[Journal Article] The pathogenic role of the BRCA2 c.7847C>T (p.Ser2616Phe) variant in breast and ovarian cancer predisposition2023
- Author(s)
  Yamazawa Kazuki、Sugano Kokichi、Tanakaya Kohji、Inoue Satomi、Murakami Haruka、Nakashima Moeko、Adachi Masataka、Oki Shinya、Makabe Takeshi、Yamashita Hiroshi、Ueki Arisa、Sasaoka Ayako、Nakashoji Ayako、Kinoshita Takayuki、Matsunaga Tatsuo、Arai Masami、Nakamura Seigo、Miyata Hiroaki、Ikegami Masachika, et al.
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 7 Pages: 2993-3002
- DOI
  10.1111/cas.15799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19751, KAKENHI-PROJECT-20K19082, KAKENHI-PROJECT-17K16881, KAKENHI-PROJECT-23K24309, KAKENHI-PROJECT-22K15571, KAKENHI-PROJECT-21H02795
[Journal Article] Case report and literature review: exploration of molecular therapeutic targets in recurrent malignant meningioma through comprehensive genetic analysis with Todai OncoPanel2023
- Author(s)
  Ohara K, Miyawaki S, Nakatomi H, Okano A, Teranishi Y, Shinya Y, Ishigami D, Hongo H, Takayanagi S, Tanaka S, Shinozaki-Ushiku A, Kohsaka S, Kage H, Oda K, Miyagawa K, Aburatani H, Mano H, Tatsuno K, Saito N
- Journal Title
  
  Front Neurol
  
  Volume: 14 Pages: 1270046-1270046
- DOI
  10.3389/fneur.2023.1270046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03074
[Journal Article] Composite Clonal Analysis Reveals Transition of NSCLC Subtypes Through Accumulation of Gene Mutations: A Case Report2022
- Author(s)
  Ando T, Kage H, Shinozaki-Ushiku A, Tatsuno K, Tsutsumi S, Nagayama K, Nakajima J, Kohsaka S, Miyagawa K, Aburatani H, Mano H, Nagase T.
- Journal Title
  
  JTO Clin Res Rep
  
  Volume: 3 Issue: 2 Pages: 100277-100277
- DOI
  10.1016/j.jtocrr.2022.100277
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795
[Journal Article] Genetic diagnosis of pseudomyxoma peritonei originating from mucinous borderline tumor inside an ovarian teratoma2022
- Author(s)
  Taguchi Ayumi、Rokutan Hirofumi、Oda Katsutoshi、Tanikawa Michihiro、Tanimoto Saki、Sone Kenbun、Mori Mayuyo、Tsuruga Tetsushi、Kohsaka Shinji、Tatsuno Kenji、Shinozaki-Ushiku Aya、Miyagawa Kiyoshi、Mano Hiroyuki、Aburatani Hiroyuki、Ushiku Tetsuo、Osuga Yutaka
- Journal Title
  
  BMC Medical Genomics
  
  Volume: 15 Issue: 1 Pages: 51-51
- DOI
  10.1186/s12920-022-01188-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K09466, KAKENHI-PROJECT-20K09662, KAKENHI-PROJECT-21H03074
[Journal Article] Clinical relevance of PD-L2 expression in surgically resected lung adenocarcinoma.2022
- Author(s)
  Takamochi K, Hara K, Hayashi T, Kohsaka S, Takahashi F, Suehara Y, Shimokawa M, Suzuki K.
- Journal Title
  
  Lung Cancer
  
  Volume: 168 Pages: 50-58
- DOI
  10.1016/j.lungcan.2022.04.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-19H03789
[Journal Article] Expert panel consensus recommendations on the use of circulating tumor DNA assays for patients with advanced solid tumors2022
- Author(s)
  Imai M, Nakamura Y, Sunami K, Kage H, Komine K, Koyama T, Amano T, Ennishi D, Kanai M, Kenmotsu H, Maeda T, Morita S, Sakai D, Bando H, Makiyama A, Suzuki T, Hirata M, Kohsaka S, Tsuchihara K, Naito Y, Yoshino T
- Journal Title
  
  Cancer Sci
  
  Volume: 113 Issue: 11 Pages: 3646-3656
- DOI
  10.1111/cas.15504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-23K24468
[Journal Article] Recommendations related to the analytical equivalence assessment of gene panel testing2022
- Author(s)
  Nagai Sumimasa、Nishihara Hiroshi、Suzuki Takayoshi、Nishio Kazuto、Taniguchi Hiroya、Tsuchihara Katsuya、Nakamura Kohei、Takamatsu Reika、Ueno Toshihide、Aburatani Hiroyuki、Kohno Takashi、Kohsaka Shinji
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 10 Pages: 3282-3290
- DOI
  10.1111/cas.15513
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06779, KAKENHI-PROJECT-22K12884, KAKENHI-PROJECT-20K18232, KAKENHI-PROJECT-21H02795
[Journal Article] CIC-Mediated Modulation of MAPK Signaling Opposes Receptor Tyrosine Kinase Inhibitor Response in Kinase-Addicted Sarcoma2022
- Author(s)
  Odintsov I, Ortiz MV, Khodos I, Mattar MS, Lui AJW, Kohsaka S, de Stanchina E, Bender JLG, Ladanyi M, Somwar R.
- Journal Title
  
  Cancer Res
  
  Volume: 82 Issue: 6 Pages: 1110-1127
- DOI
  10.1158/0008-5472.can-21-1397
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02795
[Journal Article] Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model2022
- Author(s)
  Ikeuchi H, Hirose T, Ikegami M, Takamochi K, Suzuki K, Mano H, Kohsaka S.
- Journal Title
  
  Oncogene
  
  Volume: 41 Issue: 17 Pages: 2470-2479
- DOI
  10.1038/s41388-022-02263-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795
[Journal Article] Feasibility and clinical utility of comprehensive genomic profiling of hematological malignancies2022
- Author(s)
  Fukuhara S, Oshikawa-Kumade Y, Kohsaka S et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 113 Issue: 8 Pages: 2763-2777
- DOI
  10.1111/cas.15427
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-23K24468
[Journal Article] Identification of novel prognostic and predictive biomarkers in salivary duct carcinoma via comprehensive molecular profiling2022
- Author(s)
  Kohsaka S, Tada Y, Okami K, et al.
- Journal Title
  
  NPJ Precis Oncol.
  
  Volume: 6 Issue: 1 Pages: 82-82
- DOI
  10.1038/s41698-022-00324-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09763, KAKENHI-PROJECT-21K09616, KAKENHI-PROJECT-22K06939, KAKENHI-PROJECT-22K10210, KAKENHI-PROJECT-21K16835, KAKENHI-PROJECT-21K16861, KAKENHI-PROJECT-22K16896, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-17K08753, KAKENHI-PROJECT-18K09340, KAKENHI-PROJECT-20K07417, KAKENHI-PROJECT-20K10508
[Journal Article] A multicenter investigator-initiated Phase 2 trial of E7090 in patients with advanced or recurrent solid tumor with fibroblast growth factor receptor (FGFR) gene alteration: FORTUNE trial2022
- Author(s)
  Chiba Y, Sudo K, Kojima Y, Okuma H, Kohsaka S, Machida R, Ichimura M, Anjo K, Kurishita K, Okita N, Nakamura K, Kinoshita I, Takahashi M, Matsubara J, Kusaba H, Yonemori K, Takahashi M
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 869-869
- DOI
  10.1186/s12885-022-09949-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795
[Journal Article] Primary Intracranial Spindle Cell Sarcoma, DICER1-Mutant with MDM2 Amplification Diagnosed on the Basis of Extensive Molecular Profiling2022
- Author(s)
  Nejo Takahide、Takayanagi Shunsaku、Tanaka Shota、Shinozaki-Ushiku Aya、Kohsaka Shinji、Nagata Keisuke、Yokoyama Munehiro、Sora Shigeo、Ushiku Tetsuo、Mukasa Akitake、Aburatani Hiroyuki、Mano Hiroyuki、Saito Nobuhito
- Journal Title
  
  Clinical Medicine Insights: Case Reports
  
  Volume: 15 Pages: 117954762211311-117954762211311
- DOI
  10.1177/11795476221131189
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09320, KAKENHI-PROJECT-21H02795
[Journal Article] Chronological improvement in precision oncology implementation in Japan2022
- Author(s)
  Sunami K, Naito Y, Komine K, Amano T, Ennishi D, Imai M, Kage H, Kanai M, Kenmotsu H, Koyama T, Maeda T, Morita S, Sakai D, Kohsaka S, Tsuchihara K, Saigusa Y, Yoshino T
- Journal Title
  
  Cancer Sci
  
  Volume: 113 Issue: 11 Pages: 3995-4000
- DOI
  10.1111/cas.15517
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795
[Journal Article] Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis2022
- Author(s)
  Tabata Junya、Nakaoku Takashi、Araki Mitsugu、Yoshino Ryunosuke、Kohsaka Shinji、Otsuka Ayaka、Ikegami Masachika、Ui Ayako、Kanno Shin-ichiro、Miyoshi Keiko、Matsumoto Shigeyuki、Sagae Yukari、Yasui Akira、Sekijima Masakazu、Mano Hiroyuki、Okuno Yasushi、Okamoto Aikou、Kohno Takashi
- Journal Title
  
  Cancer Research
  
  Volume: 82 Issue: 20 Pages: 3751-3762
- DOI
  10.1158/0008-5472.can-22-0834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00545, KAKENHI-PROJECT-20H00620, KAKENHI-PROJECT-21H02795
[Journal Article] Tumor mutational burden measurement using comprehensive genomic profiling assay2022
- Author(s)
  Kage Hidenori、Kohsaka Shinji、Tatsuno Kenji、Ueno Toshihide、Ikegami Masachika、Zokumasu Koichi、Shinozaki-Ushiku Aya、Nagai Sumimasa、Aburatani Hiroyuki、Mano Hiroyuki、Oda Katsutoshi
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 52 Issue: 8 Pages: 925-929
- DOI
  10.1093/jjco/hyac063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06779, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-22K12884, KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03074
[Journal Article] Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan.2022
- Author(s)
  Naito Y, Sunami K, Kage H, Komine K, Amano T, Imai M, Koyama T, Ennishi D, Kanai M, Kenmotsu H, Maeda T, Morita S, Sakai D, Watanabe K, Shirota H, Kinoshita I, Yoshioka M, Mamesaya N, Ito M, Kohsaka S, Saigusa Y, Yamamoto K, Hirata M, Tsuchihara K, Yoshino T.
- Journal Title
  
  JAMA Netw Open.
  
  Volume: 5 Issue: 12 Pages: 2245081-2245081
- DOI
  10.1001/jamanetworkopen.2022.45081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-23K24468
[Journal Article] Survival benefit of HER2-targeted or androgen deprivation therapy in salivary duct carcinoma2022
- Author(s)
  Kawakita Daisuke、Nagao Toshitaka、Takahashi Hideaki、Kano Satoshi、Honma Yoshitaka、Hirai Hideaki、Saigusa Natsuki、Akazawa Kohei、Tani Kaori、Ojiri Hiroya、Tsukahara Kiyoaki、Ozawa Hiroyuki、Okami Kenji、Kondo Takahito、Togashi Takafumi、Fushimi Chihiro、Shimura Tomotaka、Matsuki Takashi、Tada Yuichiro
- Journal Title
  
  Therapeutic Advances in Medical Oncology
  
  Volume: 14 Pages: 175883592211195-175883592211195
- DOI
  10.1177/17588359221119538
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07597, KAKENHI-PROJECT-20K09763, KAKENHI-PROJECT-21K09616, KAKENHI-PROJECT-22K06939, KAKENHI-PROJECT-21K16835, KAKENHI-PROJECT-21K16861, KAKENHI-PROJECT-22K16896, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-17K08753, KAKENHI-PROJECT-18K09340, KAKENHI-PROJECT-20K07417, KAKENHI-PROJECT-20K10508
[Journal Article] C-CAT: The National Datacenter for Cancer Genomic Medicine in Japan2022
- Author(s)
  Kohno T, Kato M, Kohsaka S, Sudo T, Tamai I, Shiraishi Y, Okuma Y, Ogasawara D, Suzuki T, Yoshida T, Mano H
- Journal Title
  
  Cancer Discov
  
  Volume: 12 Issue: 11 Pages: 2509-2515
- DOI
  10.1158/2159-8290.cd-22-0417
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-20K12071
[Journal Article] The Role of the EZH2 and H3K27me3 Expression as a Predictor of Clinical Outcomes in Salivary Duct Carcinoma Patients: A Large-Series Study With Emphasis on the Relevance to the Combined Androgen Blockade and HER2-Targeted Therapy2022
- Author(s)
  Saigusa N, Hirai H, Kohsaka S, et al.
- Journal Title
  
  Front Oncol
  
  Volume: 11 Pages: 779882-779882
- DOI
  10.3389/fonc.2021.779882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-18K09340, KAKENHI-PROJECT-20K07597, KAKENHI-PROJECT-20K09763, KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-21K09616, KAKENHI-PROJECT-21K16835, KAKENHI-PROJECT-21K16861, KAKENHI-PROJECT-21K09556, KAKENHI-PROJECT-22K10210, KAKENHI-PROJECT-17K08753, KAKENHI-PROJECT-19K16568
[Journal Article] High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer2022
- Author(s)
  Mizuno Sho、Ikegami Masachika、Koyama Takafumi、Sunami Kuniko、Ogata Dai、Kage Hidenori、Yanagaki Mitsuru、Ikeuchi Hiroshi、Ueno Toshihide、Tanikawa Michihiro、Oda Katsutoshi、Osuga Yutaka、Mano Hiroyuki、Kohsaka Shinji
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 22 Issue: 2 Pages: 227-239
- DOI
  10.1158/1535-7163.mct-22-0302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-20K09662, KAKENHI-PROJECT-21H03074
[Journal Article] Distinct properties of pure- and mixed-type high-grade fetal lung adenocarcinomas by genetic profiling and transcription factor expression.2022
- Author(s)
  Kishikawa S, Hayashi T, Saito T, Takamochi K, Sasa K, Suehara Y, Takahashi F, Sasahara N, Kohsaka S, Suzuki K, Yao T
- Journal Title
  
  Virchows Arch
  
  Volume: 480 Issue: 3 Pages: 609-619
- DOI
  10.1007/s00428-021-03247-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07469, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187
[Journal Article] Comprehensive molecular and clinicopathological profiling of desmoid tumours2021
- Author(s)
  Kohsaka Shinji、Hirata Makoto、Ikegami Masachika、Ueno Toshihide、Kojima Shinya、Sakai Tomohisa、Ito Kan、Naka Norifumi、Ogura Koichi、Kawai Akira、Iwata Shintaro、Okuma Tomotake、Yonemoto Tsukasa、Kobayashi Hiroshi、Suehara Yoshiyuki、Hiraga Hiroaki、Kawamoto Teruya、Motoi Toru、Oda Yoshinao、Matsubara Daisuke、etc
- Journal Title
  
  European Journal of Cancer
  
  Volume: 145 Pages: 109-120
- DOI
  10.1016/j.ejca.2020.12.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-20K16328, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Comparative Study on the Efficacy and Exposure of Molecular Target Agents in Non?small Cell Lung Cancer PDX Models with Driver Genetic Alterations2021
- Author(s)
  Jo Hitomi、Yagishita Shigehiro、Hayashi Yoshiharu、Ryu Shoraku、Suzuki Mikiko、Kohsaka Shinji、Ueno Toshihide、Matsumoto Yuji、Horinouchi Hidehito、Ohe Yuichiro、Watanabe Shun-ichi、Motoi Noriko、Yatabe Yasushi、Mano Hiroyuki、Takahashi Kazuhisa、Hamada Akinobu
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 21 Issue: 2 Pages: 359-370
- DOI
  10.1158/1535-7163.mct-21-0371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07036, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-21K06900
[Journal Article] Transcription start site-level expression of thyroid transcription factor 1 isoforms in lung adenocarcinoma and its clinicopathological significance.2021
- Author(s)
  Sano K, Hayashi T, Suehara Y, Hosoya M, Takamochi K, Kohsaka S, Kishikawa S, Kishi M, Saito S, Takahashi F, Kaneko K, Suzuki K, Yao T, Ishijima M, Saito T.
- Journal Title
  
  J Pathol Clin Res
  
  Volume: 7 Issue: 4 Pages: 361-374
- DOI
  10.1002/cjp2.213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07469, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Extensive functional evaluation of exon 20 insertion mutations of EGFR2021
- Author(s)
  Hirose T, Ikegami M, Endo M, Matsumoto Y, Nakashima Y, Mano H, and Kohsaka S
- Journal Title
  
  Lung Cancer
  
  Volume: 152 Pages: 135-142
- DOI
  10.1016/j.lungcan.2020.12.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K16627
[Journal Article] Correction to: The initial assessment of expert panel performance in core hospitals for cancer genomic medicine in Japan2021
- Author(s)
  Sunami K, Naito Y, Aimono E, Amano T, Ennishi D, Kage H, Kanai M, Komine K, Koyama T, Maeda T, Morita S, Sakai D, Kohsaka S, Tsuchihara K, Yoshino T.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 26 Issue: 5 Pages: 1007-1007
- DOI
  10.1007/s10147-021-01897-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02795
[Journal Article] Scapular Angiomatoid Fibrous Histiocytoma with EWSR1-CREB1 Fusion in an Adult Patient2021
- Author(s)
  Kobayashi H, Makise N, Shinozaki-Ushiku A, Ishibashi Y, Ikegami M, Kohsaka S, Ushiku T, Oda K, Miyagawa K, Aburatani H, Mano H, Tanaka S.
- Journal Title
  
  Case Rep Orthop
  
  Volume: 2021 Pages: 9434222-9434222
- DOI
  10.1155/2021/9434222
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-20K09453, KAKENHI-PROJECT-20K16167, KAKENHI-PROJECT-21H03074
[Journal Article] Rapid reprogramming of tumour cells into cancer stem cells on double-network hydrogels2021
- Author(s)
  Suzuka J, Tsuda M, Wang L, Kohsaka S, Kishida K, Semba S, Sugino H, Aburatani S, Frauenlob M, Kurokawa T, Kojima S, Ueno T, Ohmiya Y, Mano H, Yasuda K, Gong JP, Tanaka S
- Journal Title
  
  Nat Biomed Eng
  
  Volume: － Issue: 8 Pages: 914-925
- DOI
  10.1038/s41551-021-00692-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K07059, KAKENHI-PROJECT-19K20654, KAKENHI-PROJECT-19H01171, KAKENHI-PROJECT-21H03802, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-21K19878, KAKENHI-PLANNED-21H05230
[Journal Article] Histological characteristics of lung adenocarcinoma with uncommon actionable alterations: special emphasis on MET exon 14 skipping alterations2021
- Author(s)
  Hayashi Takuo、Kohsaka Shinji、Takamochi Kazuya、Kishikawa Satsuki、Ikarashi Daiki、Sano Kei、Hara Kieko、Onagi Hiroko、Suehara Yoshiyuki、Takahashi Fumiyuki、Saito Tsuyoshi、Nakatsura Tetsuya、Kitano Shigehisa、Suzuki Kenji、Yao Takashi
- Journal Title
  
  Histopathology
  
  Volume: - Issue: 7 Pages: 1-1
- DOI
  10.1111/his.14311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19K07469, KAKENHI-PROJECT-19H03789
[Journal Article] Comprehensive molecular profiling of pulmonary pleomorphic carcinoma2021
- Author(s)
  Nagano Masaaki、Kohsaka Shinji、Hayashi Takuo、Ueno Toshihide、Kojima Shinya、Shinozaki-Ushiku Aya、Morita Shigeki、Tsuda Masumi、Tanaka Shinya、Shinohara Toshiya、Omori Yuko、Sugaya Fumiko、Kato Hiroaki、Narita Yoshiaki、Nakajima Jun、Suzuki Kenji、Takamochi Kazuya、Mano Hiroyuki
- Journal Title
  
  npj Precision Oncology
  
  Volume: 5 Issue: 1 Pages: 57-57
- DOI
  10.1038/s41698-021-00201-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01171, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03802, KAKENHI-PROJECT-21K19878
[Journal Article] The initial assessment of expert panel performance in core hospitals for cancer genomic medicine in Japan2021
- Author(s)
  Sunami K, Naito Y, Aimono E, Amano T, Ennishi D, Kage H, Kanai M, Komine K, Koyama T, Maeda T, Morita S, Sakai D, Kohsaka S, Tsuchihara K, Yoshino T
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 26 Issue: 3 Pages: 443-449
- DOI
  10.1007/s10147-020-01844-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-20H05699
[Journal Article] Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers.2021
- Author(s)
  Hasegawa N, Kohsaka S, Kurokawa K, Shinno Y, Takeda Nakamura I, Ueno T, Kojima S, Kawazu M, Suehara Y, Ishijima M, Goto Y, Kojima Y, Yonemori K, Hayashi T, Saito T, Shukuya T, Takahashi F, Takahashi K, Mano H.
- Journal Title
  
  Cancer Sci
  
  Volume: 112 Issue: 10 Pages: 4393-4403
- DOI
  10.1111/cas.15084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-21K20846, KAKENHI-PROJECT-19H03789
[Journal Article] Appropriate use of cancer comprehensive genome profiling assay using circulating tumor DNA.2021
- Author(s)
  Sunami K, Bando H, Yatabe Y, Naito Y, Takahashi H, Tsuchihara K, Toyooka S, Mimori K, Kohsaka S, Uetake H, Kinoshita I, Komine K, Takeda M, Hayashida T, Tamura K, Nishio K, Yamamoto N; Working Group of a Joint Task Force of Three Academic Societies for the Promotion of Cancer Genomic Medicine.
- Journal Title
  
  Cancer Sci.
  
  Volume: 112(9) Issue: 9 Pages: 3911-3917
- DOI
  10.1111/cas.15022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05039, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-21H02795
[Journal Article] Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer.2021
- Author(s)
  Takeda Nakamura I, Kohsaka S, Ikegami M, Ueno T, Li K, Beyett T, Koyama T, Shimizu T, Yamamoto N, Takahashi F, Takahashi K, Eck M, Mano H.
- Journal Title
  
  NPJ Precision Oncology
  
  Volume: 16 Issue: 1 Pages: 66-66
- DOI
  10.1038/s41698-021-00204-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-21K12117
[Journal Article] MicroSEC; Sequence error filtering pipeline for formalin-fixed and paraffin-embedded samples.2021
- Author(s)
  Ikegami M, Kohsaka S, Hirose T, Ueno T, Inoue S, Konomata N, Yamauchi H, Mori T, Sekine S, Inamoto Y, Yatabe Y, Kobayashi H, Tanaka S, Mano H.
- Journal Title
  
  Commun Biol
  
  Volume: 4 Issue: 1 Pages: 1396-1396
- DOI
  10.1038/s42003-021-02930-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07708, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-20K07383, KAKENHI-PROJECT-20K09453, KAKENHI-PROJECT-21K12117
[Journal Article] Development of an optimal protocol for molecular profiling of tumor cells in pleural effusions at single-cell level2021
- Author(s)
  Takeda Nakamura I, Ikegami M, Hasegawa N, Hayashi T, Ueno T, Kawazu M, Yagishita S, Goto Y, Shinno Y, Kojima Y, Takamochi K, Takahashi F, Takahashi K, Mano H, Kohsaka S
- Journal Title
  
  Cancer Sci
  
  Volume: － Issue: 5 Pages: 2006-2019
- DOI
  10.1111/cas.14821
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-21K12117
[Journal Article] Programmed death-ligand 1 expression and its associations with clinicopathological features, prognosis, and driver oncogene alterations in surgically resected lung adenocarcinoma2021
- Author(s)
  Takamochi K, Hara K, Hayashi T, Kohsaka S, Takahashi F, Suehara Y, Suzuki K.
- Journal Title
  
  Lung Cancer
  
  Volume: 161 Pages: 163-170
- DOI
  10.1016/j.lungcan.2021.09.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Genetic Testing Distinguishes Multiple Chondroid Chordomas with Neuraxial Bone Metastases from Multicentric Tumors2020
- Author(s)
  Kobayashi Hiroshi、Shin Masahiro、Makise Naohiro、Shinozaki-Ushiku Aya、Ikegami Masachika、Taniguchi Yuki、Shinoda Yusuke、Kohsaka Shinji、Ushiku Tetsuo、Oda Katsutoshi、Miyagawa Kiyoshi、Aburatani Hiroyuki、Mano Hiroyuki、Tanaka Sakae
- Journal Title
  
  Case Reports in Genetics
  
  Volume: 2020 Pages: 1-6
- DOI
  10.1155/2020/8877722
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16167, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K09249
[Journal Article] Spinal solitary fibrous tumor of the neck: Next-generation sequencing-based analysis of genomic aberrations.2020
- Author(s)
  Ando M, Kobayashi H, Shinozaki-Ushiku A, Chikuda H, Matsubayashi Y, Yoshida M, Saito Y, Kohsaka S, Oda K, Miyagawa K, Aburatani H, Mano H, Yamasoba T.
- Journal Title
  
  Auris Nasus Larynx.
  
  Volume: Epub ahead of print Issue: 6 Pages: 1058-1063
- DOI
  10.1016/j.anl.2019.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K09316, KAKENHI-PROJECT-20K09405
[Journal Article] Diffuse expression of MUC6 defines a distinct clinicopathological subset of pulmonary invasive mucinous adenocarcinoma2020
- Author(s)
  Kishikawa S, Hayashi T, Saito T, Takamochi K, Kohsaka S, Sano K, Sasahara N, Sasa K, Kurihara T, Hara K, Suehara Y, Takahashi F, Suzuki K, Yao T
- Journal Title
  
  Mod Pathol
  
  Volume: － Issue: 4 Pages: 786-797
- DOI
  10.1038/s41379-020-00690-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Identification of a Novel MAN1A1-ROS1 Fusion Gene Through mRNA-based Screening for Tyrosine Kinase Gene Aberrations in a Patient with Leiomyosarcoma2020
- Author(s)
  Suehara Y, Kohsaka S, Hayashi T, Akaike K, Kurisaki-Arakawa A, Sato S, Kobayashi E, Mizuno S, Ueno T, Morii T, Okuma T, Kurihara T, Hasegawa N, Sano K, Sasa K, Okubo T, Kim Y, Mano H, Saito T
- Journal Title
  
  Clin Orthop Relat Res
  
  Volume: － Issue: 4 Pages: 838-852
- DOI
  10.1097/corr.0000000000001548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03777, KAKENHI-PROJECT-19K22680, KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-20K07415, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Mesenchymal Tumors with RREB1-MRTFB Fusion Involving the Mediastinum: Extra-Glossal Ectomesenchymal Chondromyxoid Tumors?2020
- Author(s)
  Makise N, Mori T, Kobayashi H, Nakagawa K, Ryo E, Nakajima J, Kohsaka S, Mano H, Aburatani H, Yoshida A and Ushiku T
- Journal Title
  
  Histopathology
  
  Volume: － Issue: 7 Pages: 1023-1031
- DOI
  10.1111/his.14080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K15110, KAKENHI-PROJECT-20K16167, KAKENHI-PROJECT-18K15108
[Journal Article] Activation of insulin-like growth factor-1 receptor confers acquired resistance to osimertinib in non-small cell lung cancer with EGFR T790M mutation2020
- Author(s)
  Hayakawa D, Takahashi F, Mitsuishi Y, Tajima K, Hidayat M, Winardi W, Ihara H, Kanamori K, Matsumoto N, Asao T, Ko R, Shukuya T, Takamochi K, Hayashi T, Suehara Y, Takeda Nakamura I, Ueno T, Kohsaka S, Mano H, Takahashi K
- Journal Title
  
  Thorac Cancer
  
  Volume: 11 Issue: 1 Pages: 140-149
- DOI
  10.1111/1759-7714.13255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K09669
[Journal Article] 骨・軟部腫瘍のゲノム医療とカウンセリング　軟部肉腫の新規MAN1A1-ROS1融合遺伝子の同定2020
- Author(s)
  末原義之, 高阪真路, 林大久生, 佐藤信吾, 小林英介, 金子和夫, 加藤俊介, Ladanyi Marc, 齋藤剛
- Journal Title
  
  日本整形外科学会雑誌
  
  Volume: 94 Pages: 832-840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03789
[Journal Article] Nanostring-based screening for tyrosine kinase fusions in inflammatory myofibroblastic tumors2020
- Author(s)
  Kurihara Taisei、Suehara Yoshiyuki、Akaike Keisuke、Hayashi Takuo、Kohsaka Shinji、Ueno Toshihide、Hasegawa Nobuhiko、Takagi Tatsuya、Sasa Keita、Okubo Taketo、Kim Youngji、Mano Hiroyuki、Yao Takashi、Kaneko Kazuo、Saito Tsuyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-1
- DOI
  10.1038/s41598-020-75596-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789
[Journal Article] Genomic Profiling of Multiple Primary Cancers Including Synchronous Lung Adenocarcinoma and Bilateral Malignant Mesotheliomas: Identification of a Novel BAP1 Germline Variant2020
- Author(s)
  Shinozaki-Ushiku A, Kohsaka S, Kage H, Oda K, Miyagawa K, Nakajima J, Aburatani H, Mano H, Ushiku T
- Journal Title
  
  Pathology International
  
  Volume: － Issue: 10 Pages: 775-780
- DOI
  10.1111/pin.12977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K09249
[Journal Article] がんゲノム医療の推進に向けた知識データベース構築と維持2020
- Author(s)
  高阪真路, 小山隆文, 角南久仁子, 下井辰徳, 柴田大朗
- Journal Title
  
  保健医療科学
  
  Volume: 69 Pages: 260-273
- NAID
  130007926381
- Open Access
- Data Source
  KAKENHI-PROJECT-18H02677
[Journal Article] Clinicopathological characteristics of lung adenocarcinoma with compound EGFR mutations.2020
- Author(s)
  Hayashi T, Kohsaka S, Takamochi K, Hara K, Kishikawa S, Sano K, Takahashi F, Suehara Y, Saito T, Takahashi K, Suzuki K, Yao T.
- Journal Title
  
  Human Pathology
  
  Volume: 14 Pages: 42-51
- DOI
  10.1016/j.humpath.2020.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-19K07469
[Journal Article] RET inhibition in novel patient-derived models of RET-fusion positive lung adenocarcinoma reveals a role for MYC upregulation2020
- Author(s)
  Hayashi T, Odintsov I, Smith RS, Ishizawa K, Liu AJW, Delasos L, Kurzatkowski C, Tai H, Gladstone E, Vojnic M, Kohsaka S, Suzawa K, Liu Z, Kunte S, Mattar MS, Khodos I, Davare MA, Drilon A, Cheng E, Stanchina E, Ladanyi M, Somwar R
- Journal Title
  
  Dis Model Mech
  
  Volume: － Issue: 2 Pages: 1-11
- DOI
  10.1242/dmm.047779
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-17K09641
[Journal Article] Transformation from EGFR/PTEN co-mutated lung adenocarcinoma to small cell carcinoma in lymph node metastasis2020
- Author(s)
  Hayashi T, Takamochi K, Kohsaka S, Kishikawa S, Suehara Y, Takahashi F, Suzuki K, Saito T, Yao T
- Journal Title
  
  Pathology International
  
  Volume: － Issue: 5 Pages: 295-299
- DOI
  10.1111/pin.12919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2)2020
- Author(s)
  Naito Y, Aburatani H, Amano T, Baba E, Furukawa T, Hayashida T, Hiyama E, Ikeda S, Kanai M, Kato M, Kinoshita I, Kiyota N, Kohno T, Kohsaka S, et al.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: － Issue: 2 Pages: 233-283
- DOI
  10.1007/s10147-020-01831-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K09249, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-19H01056
[Journal Article] High-throughput functional evaluation of BRCA2 variants of unknown significance.2020
- Author(s)
  Ikegami, M., Kohsaka, S., Ueno, T., Momozawa, Y., Inoue, S., Tamura, K., Shimomura, A., Hosoya, N., Kobayashi, H., Tanaka, S., Mano, H.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 2573-2573
- DOI
  10.1038/s41467-020-16141-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07708, KAKENHI-PROJECT-20K08127, KAKENHI-PROJECT-20K09453, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19J13207
[Journal Article] Comprehensive clinicopathological and molecular analysis of primary malignant melanoma of the oesophagus2020
- Author(s)
  Tsuyama Sho、Kohsaka Shinji、Hayashi Takuo、Suehara Yoshiyuki、Hashimoto Takashi、Kajiyama Yoshiaki、Tsurumaru Masahiko、Ueno Toshihide、Mano Hiroyuki、Yao Takashi、Saito Tsuyoshi
- Journal Title
  
  Histopathology
  
  Volume: 78 Issue: 2 Pages: 240-251
- DOI
  10.1111/his.14210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789
[Journal Article] The Brain Microenvironment Induces DNMT1 Suppression and Indolence of Metastatic Cancer Cells2020
- Author(s)
  Hirata Eishu、Ishibashi Kojiro、Kohsaka Shinji、Shinjo Keiko、Kojima Shinya、Kondo Yutaka、Mano Hiroyuki、Yano Seiji、Kiyokawa Etsuko、Sahai Erik
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 9 Pages: 101480-101480
- DOI
  10.1016/j.isci.2020.101480
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20598, KAKENHI-PROJECT-20K16327, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-20H03510, KAKENHI-PROJECT-19K23911
[Journal Article] Assessment of Predictive Biomarkers of the Response to Pazopanib Based on an Integrative Analysis of High-grade Soft-tissue Sarcomas: Analysis of a Tumor Sample from a Responder and Patients with Other Soft-tissue Sarcomas2020
- Author(s)
  Suehara Y.、Kohsaka S.、Yamaguchi S.、Hayashi T.、Kurihara T.、Sano K.、Sasa K.、Akaike K.、Ueno T.、Kojima S.、Ikegami M.、Mizuno S.、Okubo T.、Kim Y.、Kaneko K.、Saito T.、Kato S.、Mano H.
- Journal Title
  
  Clinical Orthopaedics & Related Research
  
  Volume: 478 Issue: 11 Pages: 2461-2476
- DOI
  10.1097/corr.0000000000001322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07740, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789
[Journal Article] がんゲノム医療におけるVUS（variant of unknown significance）の評価2020
- Author(s)
  高阪真路
- Journal Title
  
  がん分子標的治療
  
  Volume: 18 Pages: 72-77
- Data Source
  KAKENHI-PROJECT-18H02677
[Journal Article] Identification of Novel CD74-NRG2α Fusion From Comprehensive Profiling of Lung Adenocarcinoma in Japanese Never or Light Smokers2020
- Author(s)
  Kohsaka S, Hayashi T, Nagano M, Ueno T, Kojima S, Kawazu M, Shiraishi Y, Kishikawa S, Suehara Y, Takahashi F, Takahashi K, Suzuki K, Takamochi K, Mano H
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: － Issue: 6 Pages: 30098-8
- DOI
  10.1016/j.jtho.2020.01.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-17K09669
[Journal Article] Small lung tumor biopsy samples are feasible for high quality targeted next generation sequencing2019
- Author(s)
  Kage Hidenori、Kohsaka Shinji、Shinozaki‐Ushiku Aya、Hiraishi Yoshihisa、Sato Jiro、Nagayama Kazuhiro、Ushiku Tetsuo、Takai Daiya、Nakajima Jun、Miyagawa Kiyoshi、Aburatani Hiroyuki、Mano Hiroyuki、Nagase Takahide
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 8 Pages: 2652-2657
- DOI
  10.1111/cas.14112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-17K10778
[Journal Article] Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin‐fixed paraffin‐embedded specimens2019
- Author(s)
  Kohsaka Shinji、Tatsuno Kenji、Ueno Toshihide、et al.
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 4 Pages: 1464-1479
- DOI
  10.1111/cas.13968
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-17K19608, KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-17K07195, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-18H02677
[Journal Article] Detection of circulating sarcoma tumor cells using a microfluidic chip-type cell sorter.2019
- Author(s)
  Hasegawa N, Takeda Nakamura I, Ueno T, Kojima S, Kawazu M, Akaike K, Okubo T, Takagi T, Suehara Y, Hayashi T, Saito T, Kaneko K, Mano H, Kohsaka S.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 20047-20047
- DOI
  10.1038/s41598-019-56377-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-15KK0353
[Journal Article] Protein Expression Profiles Corresponding to Histological Changes with Denosumab Treatment in Giant Cell Tumors of Bone.2019
- Author(s)
  Suehara Y, Okubo T, Kurihara T, Hayashi T, Kohsaka S, Kazuno S, Sano K, Hasegawa N, Miura Y, Akaike K, Kim Y, Takamochi K, Takahashi F, Ueno T, Kaneko K, Saito T.
- Journal Title
  
  Proteomics Clin Appl
  
  Volume: 13 Issue: 5 Pages: 1800147-1800147
- DOI
  10.1002/prca.201800147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-15KK0353
[Journal Article] Pediatric soft tissue tumor of the upper arm with LMNA-NTRK1 fusion2018
- Author(s)
  Kohsaka Shinji、Saito Tsuyoshi、Akaike Keisuke、Suehara Yoshiyuki、Hayashi Takuo、Takagi Tatsuya、Kaneko Kazuo、Ueno Toshihide、Kojima Shinya、Kohashi Ken-ichi、Mano Hiroyuki、Oda Yoshinao、Yao Takashi
- Journal Title
  
  Human Pathology
  
  Volume: 72 Pages: 167-173
- DOI
  10.1016/j.humpath.2017.08.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-17K08722, KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964
[Journal Article] PPP2R1A regulated by PAX3/FOXO1 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma.2018
- Author(s)
  Akaike K, Suehara Y, Kohsaka S, Hayashi T, Tanabe Y, Kazuno S, Mukaihara K, Toda-Ishii M, Kurihara T, Kim Y, Okubo T, Hayashi Y, Takamochi K, Takahashi F, Kaneko K, Ladanyi M, Saito T.
- Journal Title
  
  Oncotarget
  
  Volume: 9(38) Issue: 38 Pages: 25206-25215
- DOI
  10.18632/oncotarget.25392
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070, KAKENHI-PROJECT-18H02677
[Journal Article] IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.2018
- Author(s)
  Tanabe Y, Suehara Y, Kohsaka S, Hayashi T, Akaike K, Mukaihara K, Kurihara T, Kim Y, Okubo T, Ishii M, Kazuno S, Kaneko K, Saito T.
- Journal Title
  
  Oncotarget
  
  Volume: 9(18) Issue: 18 Pages: 14428-14443
- DOI
  10.18632/oncotarget.24467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070
[Journal Article] Proteomic signatures corresponding to the SS18/SSX fusion gene in synovial sarcoma.2018
- Author(s)
  Ishii M, Suehara Y, Sano K, Kohsaka S, Hayashi T, Kazuno S, Akaike K, Mukaihara K, Kim Y, Okubo T, Takamochi K, Takahashi F, Kaneko K, Saito T.
- Journal Title
  
  Oncotarget
  
  Volume: 9(101) Issue: 101 Pages: 37509-37519
- DOI
  10.18632/oncotarget.26493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070, KAKENHI-PROJECT-18H02677
[Journal Article] Tumor clonality and resistance mechanisms in EGFR mutation-positive non-small-cell lung cancer: implications for therapeutic sequencing2018
- Author(s)
  Kohsaka S, Petronczki M, Solca F, Maemondo M
- Journal Title
  
  Future Oncol
  
  Volume: 15 Issue: 6 Pages: 637-652
- DOI
  10.2217/fon-2018-0736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02677
[Journal Article] A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer2017
- Author(s)
  Kohsaka Shinji、Nagano Masaaki、Ueno Toshihide、Suehara Yoshiyuki、Hayashi Takuo、Shimada Naoko、Takahashi Kazuhisa、Suzuki Kenji、Takamochi Kazuya、Takahashi Fumiyuki、Mano Hiroyuki
- Journal Title
  
  Science Translational Medicine
  
  Volume: 9 Issue: 416 Pages: 6566-6566
- DOI
  10.1126/scitranslmed.aan6566
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-16K10691, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26461200
[Journal Article] Cabozantinib and dastinib exert anti-tumor activity in alveolar soft part sarcoma2017
- Author(s)
  Mukaihara K, Tanabe Y, Kubota D, Akaike K, Hayashi T, Mogushi K, Hosoya M, Sato S,Kobayashi E, Okubo T, Kohsaka S, Saito T, Kaneko K, Suehara Y.
- Journal Title
  
  PLoS One
  
  Volume: 12(9) Issue: 9 Pages: 0185321-0185321
- DOI
  10.1371/journal.pone.0185321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10847, KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-16H07186
[Journal Article] DNA mismatch repair deficiency in surgically resected lung adenocarcinoma: Microsatellite instability analysis using the Promega panel2017
- Author(s)
  Takamochi Kazuya、Takahashi Fumiyuki、Suehara Yoshiyuki、Sato Eiichi、Kohsaka Shinji、Hayashi Takuo、Kitano Shigehisa、Uneno Toshihide、Kojima Shinya、Takeuchi Kengo、Mano Hiroyuki、Suzuki Kenji
- Journal Title
  
  Lung cancer
  
  Volume: 110 Pages: 26-31
- DOI
  10.1016/j.lungcan.2017.05.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-16K10691, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26461200
[Journal Article] Expression of F-actin-capping protein subunit beta is associated with cell growth and motility in epithelioid sarcoma.2016
- Author(s)
  Mukaihara K, Suehara Y*, Kohsaka S, Kubota D, Toda-Ishii M, Akaike K, Fujimura T, Kobayashi E, Yao T, Ladanyi, M, Kaneko K, Saito T.
- Journal Title
  
  BMC cancer.
  
  Volume: 16(1) Issue: 1 Pages: 206-206
- DOI
  10.1186/s12885-016-2235-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353
[Journal Article] Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab.2016
- Author(s)
  Mukaihara K, Suehara Y, Kohsaka S, Akaike K, Tanabe Y, Kubota D, Ishii M, Fujimura T, Kazuno S, Okubo T, Takagi T, Yao T, Kaneko K, Saito T.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 2 Pages: e0148401-e0148401
- DOI
  10.1371/journal.pone.0148401
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670286, KAKENHI-PROJECT-26893267, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070, KAKENHI-PROJECT-15KK0353
[Journal Article] LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.2016
- Author(s)
  Takanobu Jotatsu, Shigehiro Yagishita, Ken Tajima, Fumiyuki Takahashi, Kaoru Mogushi, Moulid Hidayat, Aditya Wirawan, Ryo Ko, Ryota Kanemaru, Naoko Shimada, Keiko Mitani, Tsuyoshi Saito, Kazuya Takamochi, Kenji Suzuki, Shinji Kohsaka, Shinya Kojima, Hiroshi Mukae, Kazuhiro Yatera, Kazuhisa Takahashi.
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 9 Pages: 86-94
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02676
[Journal Article] Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors2016
- Author(s)
  Ishii M, Akaike K, Suehara Y, Mukaihara K, Kubota K , Kohsaka S, Okubo T, Mitani K, Mogushi K, Takagi T, Kaneko K, Yao T, Saito T.
- Journal Title
  
  Modern Pathology.
  
  Volume: 29 Issue: 11 Pages: 1424-1432
- DOI
  10.1038/modpathol.2016.138
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26893267, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26670286, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070, KAKENHI-PROJECT-15KK0353
[Journal Article] Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults2016
- Author(s)
  Takahiko Yasuda, Shinobu Tsuzuki, Masahito Kawazu, Fumihiko Hayakawa, Shinya Kojima, Toshihide Ueno, Naoto Imoto, Shinji Kohsaka, Akiko Kunita, Koichiro Doi, Toru Sakura, Toshiaki Yujiri, Eisei Kondo, Katsumichi Fujimaki, Yasunori Ueda, Yasutaka Aoyama, Shigeki Ohtake, Junko Takita, Eirin Sai, Masafumi Taniwaki, et al.
- Journal Title
  
  Nature genetics
  
  Volume: in press Issue: 5 Pages: 409-417
- DOI
  10.1038/ng.3535
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09472, KAKENHI-PROJECT-25461432, KAKENHI-PROJECT-26670493, KAKENHI-PROJECT-25860289, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-26293242, KAKENHI-PROJECT-26461421, KAKENHI-PROJECT-16K09856
[Presentation] 大規模データ解析が拓くがんゲノム医療のNext stage2023
- Author(s)
  高阪真路
- Organizer
  第113 回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] Exploratory novel biomarker and resistance mechanism of milademetan, an MDM2 inhibitor, in amplified MDM2 intimal sarcoma from an open-label phase 1b/2 trial (NCCH1806/MK004).2023
- Author(s)
  Takafumi Koyama、Toshio Shimizu、Yuki Kojima、Kazuki Sudo、Hitomi Sumiyoshi Okuma、Tatsunori Shimoi、Hitoshi Ichikawa、Shinji Kohsaka、Akihiko Yoshida、Naoko Matsui、Kenichi Nakamura、Noboru Yamamoto、Kan Yonemori
- Organizer
  2023 ASCO Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] J-PDX ライブラリーにおける Short Tandem Repeat 解析による品質管理の有用性検討2023
- Author(s)
  吉野友美、柳下薫寛、牛江千明、大藤千里、高橋亜子、高阪真路、上野敏秀、濱田哲暢
- Organizer
  第82日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 我が国におけるがんゲノム医療の現状と展望2023
- Author(s)
  高阪真路
- Organizer
  日本頭頸部外科学会第12回教育セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 次世代 CGP 検査の幕開け―GenMineTOP への期待―2023
- Author(s)
  高阪真路
- Organizer
  第61回日本癌治療学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 次世代CGP検査の幕開け2023
- Author(s)
  高阪真路
- Organizer
  第82日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] RNAシークエンスが拓く新たながんゲノム医療と将来展望2023
- Author(s)
  高阪真路
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 次世代CGP検査が拓く新たながんゲノム医療2023
- Author(s)
  高阪真路
- Organizer
  第82日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 膵癌患者の組織とリキッドバイオプシー検体を用いた分子プロファイリングの有用性2023
- Author(s)
  柳垣充、宇和川匡、上野敏秀、今井健太、高橋数冴、新井田厚司、恒松雅、白井祥睦、春木孝一郎、古川賢英、後町武志、池上徹、間野博行、高阪真路
- Organizer
  第82日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] Development of a comprehensive assay for the molecular profiling of cancer by target enrichment from FFPE specimens2023
- Author(s)
  Shinji Kohsaka
- Organizer
  2023 Joint Winter Meeting with RSM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 肺腺癌におけるRNA解析の臨床的妥当性・有用性の検討2023
- Author(s)
  寺島祐樹、池内洋史、朴秀煥、上野敏秀、小島進也、高持一矢、高阪真路
- Organizer
  第113 回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] がんゲノム研究が拓く新しい医療2023
- Author(s)
  高阪真路
- Organizer
  第29回日本遺伝性腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] ゲノム研究で新しいがん治療法を創る2023
- Author(s)
  高阪真路
- Organizer
  WCRW2023
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 日本国内固形癌患者における NTRK 融合遺伝子の保有率を調査する後方視的観察研究2023
- Author(s)
  高阪真路
- Organizer
  第61回日本癌治療学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] Opening a new era of omics-based medicine2023
- Author(s)
  高阪真路
- Organizer
  第14 回国際ゲノム会議
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 日米におけるがん遺伝子プロファイリング検査開発の展望2023
- Author(s)
  高阪真路
- Organizer
  第56回日本整形外科学会骨・軟部腫瘍学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] Liquid Biopsy from bench to bed side2023
- Author(s)
  高阪真路
- Organizer
  第82日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 我が国におけるがんゲノム医療の現状と展望2023
- Author(s)
  高阪真路
- Organizer
  第35回日本内分泌外科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] TOP-Lパネルの開発2023
- Author(s)
  高阪真路
- Organizer
  第8回Liquid Biopsy 研究会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] ゲノム研究で新しいがん治療法を創る2023
- Author(s)
  高阪真路
- Organizer
  第40回分子病理学研究会クラークシンポジウム
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 人工微小環境ポリマーアレイによる新規セルフェノミクスの創出とがん層別化法の開発2022
- Author(s)
  椨康一、高阪真路、秀拓一郎、田賀哲也
- Organizer
  第81日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] BRCA機能的スクリーニングとHBOC診療の個別化2022
- Author(s)
  高阪真路
- Organizer
  第 2 回 JOHBOC 学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 東大オンコパネル（TOP）を用いたプレシジョンメディシン（先進医療 B）2022
- Author(s)
  鹿毛秀宣、牛久綾、石垣和祥、佐藤悠佑、田辺真彦、田中將太、谷川道洋、渡邊広祐、高阪真路、辰野健二、牛久哲男、油谷浩幸、間野博行、宮川清、織田克利
- Organizer
  第81日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] FGFR 遺伝子変異のがん化能および薬剤感受性に対する網羅的解析2022
- Author(s)
  中村育子、高阪真路、上野敏秀、高橋史行、高橋和久、間野博行
- Organizer
  第81日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] シングルセル解析の臨床応用2022
- Author(s)
  高阪真路
- Organizer
  第7回クリニカルバイオバンク学会シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] RNA解析が拓く新たながんゲノム医療2022
- Author(s)
  高阪真路
- Organizer
  第60回日本癌治療学会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 遺伝子プロファイリングを目指した Ghost Cytometry によるcirculating tumor cell 分取実験2022
- Author(s)
  伊田英恵、河村踊子、長谷川延彦、上野敏秀、小山隆文、米盛勧、大江裕一郎、山本昇、太田禎生、間野博行、高阪真路
- Organizer
  第81日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] がんゲノム医療が加速する研究開発2022
- Author(s)
  高阪真路
- Organizer
  第73回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 骨軟部腫瘍における血漿中のcell-free RNAを用いた高感度融合遺伝子解析2022
- Author(s)
  長谷川延彦, 高阪真路, 岩田慎太郎, 林大久生, 齋藤剛, 佐々恵太, 窪田大介, 末原義之 , 高木辰哉, 石島旨章
- Organizer
  第95回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 網羅的薬効予測マーカー探索プラットフォームの構築2022
- Author(s)
  池内洋史、松野悠介、池上政周、小島進也、大熊ひとみ、小島勇貴、米盛勧、谷田部恭、吉岡研一、間野博行、高阪真路
- Organizer
  第81日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] ユーイング肉腫における診断・治療モニタリングツールとしての血漿中の cell-free RNA の可能性2022
- Author(s)
  長谷川延彦、窪田大介、高木辰哉、齋藤剛、岩田慎太郎、川井章、高阪真路、間野博行
- Organizer
  第81日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] がんゲノム医療におけるRNAシークエンスの活用法2022
- Author(s)
  高阪真路
- Organizer
  第81日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] がん遺伝子プロファイリング検査におけるリキッドバイオプシーの最適化2022
- Author(s)
  高阪真路
- Organizer
  第 63 回日本臨床細胞学会総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] Ewing肉腫における血漿中のcell-free RNAを用いた高感度融合遺伝子解析2022
- Author(s)
  長谷川延彦, 高阪真路, 岩田慎太郎, 川井章, 齋藤剛, 佐々恵太, 窪田大介, 末原義之, 高木辰哉, 間野博行, 石島旨章
- Organizer
  第95回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] リキッドバイオプシーの実践2022
- Author(s)
  高阪真路
- Organizer
  第19回日本婦人科がん会議
- Invited
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 循環腫瘍細胞を用いた遺伝子プロファイリング検査の構築2022
- Author(s)
  高阪真路
- Organizer
  第 63 回日本臨床細胞学会総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 小児固形がんにおける循環腫瘍 DNA を用いたリキッドバイオプシーの臨床的有用性の検討2022
- Author(s)
  柳垣充、荒川歩、上野敏秀、大熊ひとみ、池上徹、間野博行、高阪真路
- Organizer
  第81日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] がんゲノム医療におけるリキッドバイオプシーの有用性と現状2021
- Author(s)
  高阪真路
- Organizer
  第80日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] がんゲノム医療におけるリキッドバイオプシーの有用性と現状2021
- Author(s)
  高阪真路
- Organizer
  第62回日本臨床細胞学会総会春期大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] 発がん関連遺伝子における生殖細胞系列バリアントのハイスループット機能解析法2021
- Author(s)
  高阪真路
- Organizer
  遺伝性腫瘍セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] がん個別化医療の実現に向けた戦略的研究開発2021
- Author(s)
  高阪真路
- Organizer
  AI技術が切り拓く新たなリウマチ学に向けた教育シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] High throughput functional analysis for the clinical annotation in cancer genome medicine2021
- Author(s)
  Shinji Kohsaka
- Organizer
  1stJCA-AACR Precision Cancer Medicine International Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02795
[Presentation] Liquid型パネルとC-CATリポジトリの活用2021
- Author(s)
  高阪真路
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] がん個別化医療の実現に向けた戦略的研究開発2020
- Author(s)
  高阪真路
- Organizer
  AI技術が切り拓く新たなリウマチ学に向けた教育シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] がんゲノム医療におけるリキッドバイオプシーの実践2020
- Author(s)
  高阪真路
- Organizer
  第109回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] Development of rapid diagnosis of cancer stem cells using double-network hydrogels2020
- Author(s)
  Masumi Tsuda, Jun Suzuka, Lei Wang, Shinji Kohsaka, Hiroyuki Mano, Shinya Tanaka
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01171
[Presentation] 個別化がんゲノム医療の実現に向けた知識データベースの構築2020
- Author(s)
  高阪真路
- Organizer
  第58回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] がんゲノム医療の現況と展望2020
- Author(s)
  高阪真路
- Organizer
  第33回横浜市立大学がんプロ合同セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] Detection of Fusion Genes in Inflammatory Myofibroblastic Tumor/Inflammatory Pseudotumor by Nanostring-Based Screening System.2020
- Author(s)
  Kurihara T, Suehara Y, Akaike K, Hayashi T, Kohsaka S, Hasegawa N, Takagi T, Okubo T, Kim Y, Yao T, Kaneko K, Saito T.
- Organizer
  USCAP, the 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Detection of Fusion Genes in Inflammatory Myofibroblastic Tumor/Inflammatory Pseudotumor by Nanostring-Based Screening System.2020
- Author(s)
  Kurihara T, Suehara Y, Akaike K, Hayashi T, Kohsaka S, Hasegawa N, Takagi T, Okubo T, Kim Y, Yao T, Kaneko K, Saito T.
- Organizer
  USCAP, the 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] シングルセル解析のがんゲノム医療への応用2019
- Author(s)
  高阪真路
- Organizer
  第16回日本病理学会カンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] anoString analyses of tyrosine kinase fusion genes in IMT / IPT2019
- Author(s)
  Kurihara T, Suehara Y, Sano K, Akaike K, Hayashi T, Kohsaka S, Hasegawa N, Takagi T, Okubo T, Yao T, Kaneko K Saito T.
- Organizer
  Connective Tissue Oncology Society, 24th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Nanostringを用いたinflammatory myofibroblastic tumor/Inflammatory pseudotumorにおける融合遺伝子解析.2019
- Author(s)
  栗原大聖, 末原義之, 赤池慶祐, 林大久生, 長谷川延彦, 高阪真路, 八尾隆史, 金子和夫, 齋藤剛.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] がん遺伝子における意義不明バリアントのハイスループット機能解析法2019
- Author(s)
  高阪真路, 長野匡晃, 上野敏秀, 間野博行
- Organizer
  第17回日本臨床学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] シンポジウム：骨・軟部腫瘍のゲノム医療とカウンセリング_軟部肉腫のTyrosine kinase融合遺伝子・遺伝子変異体の探索2019
- Author(s)
  末原義之, 高阪真路, 栗崎愛子, 林大久生, 赤池慶祐, 佐藤信吾, 小林英介, 金子和夫, 間野博行, 齋藤剛.
- Organizer
  52回日本整形外科学会骨・軟部腫瘍学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] がん研究からがんゲノム医療への応用2019
- Author(s)
  高阪真路
- Organizer
  2019年度第1回教育研修・講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 骨軟部肉腫におけるマイクロ流路チップ・セルソーターを使用した循環腫瘍細胞の同定と次世代シーケンシング2019
- Author(s)
  長谷川延彦, 高阪真路, 中村育子, 末原義之, 高木辰哉, 林大久生, 斎藤剛, 金子和夫, 間野博行.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] がん個別化医療の実現に向けた戦略的研究開発2019
- Author(s)
  高阪真路
- Organizer
  第237回呼吸器学会関東地方会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 軟部肉腫pazopanib著効例の12q13-14遺伝子増幅変化.2019
- Author(s)
  末原義之, 高阪真路, 山口茂夫, 林大久生, 栗原大聖, 赤池慶祐, 金子和夫, 齋藤剛, 間野博行, 加藤俊介.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Clinicopathological characteristics of lung adenocarcinoma with EGFR compound mutations.2019
- Author(s)
  Hayashi T, Kohsaka S, Takamochi K, Takahashi F, Suehara Y, SaitoT, Suzuki K, Mano H, Yao T.
- Organizer
  USCAP, the 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] ハイスループット遺伝子機能解析法のがんゲノム医療への応用2019
- Author(s)
  高阪真路
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 軟部肉腫のROS1融合遺伝子同定とその機能解析.2019
- Author(s)
  末原義之, 高阪真路, 林大久生, 赤池慶祐, 佐藤信吾, 小林英介, 金栄智, 大久保武人, 金子和夫, 間野博行, 齋藤剛.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Application of a High-throughput Functional Evaluation of Variants of Unknown Significance to Personalized Medicine2019
- Author(s)
  高阪真路
- Organizer
  第38回札幌国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] EGFR遺伝子exon 20挿入変異に対するハイスループット機能解析2019
- Author(s)
  廣瀬毅, 高阪真路, 池上政周, 間野博行
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] Nanostringを用いたIMT/IPTにおけるチロシンキナーゼ融合遺伝子の解析2019
- Author(s)
  栗原大聖, 末原義之, 赤池慶祐, 長谷川延彦, 林大久生, 高阪真路, 高木辰哉, 八尾隆史, 金子和夫, 斎藤剛.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 骨・軟部肉腫における血中循環腫瘍細胞の同定.2019
- Author(s)
  長谷川延彦, 高阪真路, 末原義之, 赤池慶祐, 大久保武人, 高木辰哉, 林大久生, 齋藤剛, 金子和夫, 間野博行.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Integrative analysis including whole genome sequencing, transcriptome sequencing, and phospho-protein expression profiling of super responder to pazopanib in high-grade soft tissue sarcomas.2019
- Author(s)
  Suehara Y, Kohsaka S, Yamaguchi S, Hayashi T, Kurihara T, Akaike K, Ueno T, Kojima S, Ikegami M, Mizuno S, Kaneko K , Kato S, Mano H, Saito T.
- Organizer
  20th International Symposium on Limb Salvage
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] がんゲノム医療の実現にむけたがん遺伝子ハイスループット機能解析法の構築2019
- Author(s)
  高阪真路
- Organizer
  第30回日本医学会総会
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] ゲノム医療におけるリキッドバイオプシーの有用性2019
- Author(s)
  高阪真路, 間野博行
- Organizer
  第108回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 軟部肉腫pazopanib著効例の特徴的遺伝子増幅変化.2019
- Author(s)
  末原義之, 高阪真路, 山口茂夫, 林大久生, 栗原大聖, 赤池慶祐, 金子和夫, 齋藤剛, 間野博行, 加藤俊介.
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] ハイスループット機能解析法のがんゲノム医療への応用2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] NGSのゲノム解析レポートの読み方2018
- Author(s)
  高阪真路
- Organizer
  第107回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] がんゲノム医療のためのハイスループット機能解析法の確立2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第107回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] がん遺伝子ハイスループット機能解析によるがん生物学の統合的理解2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第41回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 肺がん関連遺伝子変異のハイスループット機能解析2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第22回がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] High-throughput functional evaluation of variants of unknown significance in ERBB22018
- Author(s)
  Masaaki Nagano, Shinji Kohsaka, Toshihide Ueno, Shinya Kojima, Masachika Ikegami, Ikuko Takeda, and Hiroyuki Mano
- Organizer
  American Association for Cancer Research Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] Application of a High-throughput Functional Evaluation of Variants of Unknown Significance to Personalized Medicine2018
- Author(s)
  Shinji Kohsaka, Masaaki Nagano, and Hiroyuki Mano
- Organizer
  The 6th JCA-AACR Special Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 意義不明変異陽性がんに対する分子標的治療2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] Comprehensive mRNA-based screen for tyrosine kinase fusions and a de novo alternative transcription initiation site in soft tissue sarcomas.2018
- Author(s)
  Suehara Y, Kohsaka S, Kurisaki A, Akaike K, Hayashi T, Mogushi K, Okubo T, Kim Y, Sato S, Kobayashi E, Kaneko K, Mano H, Saito T.
- Organizer
  European Society For Medical Oncology ASIA,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] A complete responder to pazopanib in high-grade soft tissue sarcomas.2017
- Author(s)
  Suehara Y, Kohsaka S, Yamaguchi S, Akaike K, Hayashi T, Tanabe Y, Ueno T, Kojima S, Takeda I, Hayashi R, Saito T, Mano H, Kato S.
- Organizer
  Connective Tissue Oncology Society, 22th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] Proteomic approaches reveal that inhibition of the IRE1/XBP1 pathway reduces tumor growth in Ewing's sarcoma.2017
- Author(s)
  Tanabe Y, Suehara Y, Kohsaka S, Mukaihara K, Kubota D, Akaike K, Ishii M, Kazuno S, Mineki R, Kaneko K, Ladanyi M, Saito T.
- Organizer
  the 63th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  San Diego, USA
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] Proteomics analysis of characteristic histological changes with Denosumab treatment in giant cell tumors of bone.2017
- Author(s)
  SueharaY, Mukaihara K, TanabeY, Kohsaka S, Kazuno S, Ishii M, Akaike K, Kubota D, Kaneko K, Saito T.
- Organizer
  the 63th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  San Diego, USA
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] Microsatellite instability analysis using the Promega panel in lung adenocarcinoma.2016
- Author(s)
  Takamochi K, Takahashi F, Suehara Y, Kitano S, Sato E, Kohsaka S, Hayashi T, Mano H, Suzuki K.
- Organizer
  Chest Annual Meeting 2016
- Place of Presentation
  Los Angels, USA
- Year and Date
  2016-10-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] Protein Expression Profiles Corresponding To Histological Changes With Denosumab Treatment in Giant Cell Tumors of Bone.2016
- Author(s)
  Suehara Y, Mukaihara K, Tanabe Y, Kohsaka S, Kazuno S, Ishii M, Akaike K, Kubota D, Kaneko K, Saito T.
- Organizer
  Connective Tissue Oncology Society, 21th Annual Meeting,
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] Proteomic approaches revealed inhibition of IRE1/XBP1 pathway reduces tumor growths in Ewing's sarcomas.2016
- Author(s)
  Tanabe Y, Suehara Y, Kohsaka S, Mukaihara K, Kubota D, Akaike K, Ishii M, Kazuno S, Mineki R, Kaneko K, Ladanyi M, Saito T.
- Organizer
  Connective Tissue Oncology Society, 21th Annual Meeting,
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] The Regulation of Malignant Transformation by PPP2R1A in Alveolar Rhabdomyosarcoma Based On A Proteomic Approach Corresponding To The PAX3/FOXO1 Fusion Gene.2016
- Author(s)
  Akaike K, Suehara Y, Kohsaka S, Mukaihara K, Ishii M, Kubota D, Tanabe Y, Kazuno S, Mineki R, Fujimura T, Kaneko K, Ladanyi M, Saito T.
- Organizer
  Connective Tissue Oncology Society, 21th Annual Meeting,
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
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Kohsaka Shinji 高阪 真路

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Comprehensive search for mechanisms of resistance to molecularly targeted therapiesPrincipal Investigator

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Comprehensive investigation of tumorigenesis mechanism induced by sarcoma-related fusion genesPrincipal Investigator

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[Book] がんゲノム病理学2021

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[Book] C-CAT調査結果の読み方. がんゲノム医療遺伝子パネル検査実践ガイド2020

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[Book] BIO Clinica 2019年 8月臨時増刊号 VUS解釈のためのハイスループット機能解析法2019

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[Book] Precision Medicine 2019年2月号 がんクリニカルシークエンス検査の開発と臨床応用2019

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Kohsaka Shinji 高阪真路

[Book] Precision Medicine　2019年2月号　がんクリニカルシークエンス検査の開発と臨床応用2019

[Book] 病理と臨床 2019年10月号シングルセル解析遺伝子解析2019

[Book] 医学のあゆみがん研究10か年戦略の成果と課題プレシジョンメディシンの実現に向けた意義不明変異の解釈2019

[Book] 特集　がんゲノム医療・Precision Medicineの展開と諸問題2018

[Book] 実験医学増刊 Vol.36 No.15　動き始めた　がんゲノム医療2018