Kohsaka Shinji 高阪真路

Researcher Number	00627119
Affiliation *help	2018 : 東京大学, 医学(系)研究科(研究院), 助教 2016 – 2017 : 東京大学, 大学院医学系研究科(医学部), 特任助教 2014 : 東京大学, 大学院医学系研究科（医学部）, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related Except Principal Investigator Orthopaedic surgery
Keywords	Except Principal Investigator 骨軟部腫瘍 / チロシンキナーゼ / ゲノム解析 / 遺伝子変異体 / ゲノム / 癌 / 整形外科 / 転写変異体 / 骨軟部肉腫 / 融合遺伝子

肉腫融合遺伝子による発がんメカニズムの統合的探索Principal InvestigatorOngoing
- Principal Investigator
  
  高阪真路
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
骨軟部腫瘍における診断マーカーの同定と腫瘍概念の再構築を目指した融合遺伝子の探索Ongoing
- Principal Investigator
  
  松田浩一
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
「希少癌」骨軟部腫瘍のチロシンキナーゼ遺伝子転写変異体の探索Ongoing
- Principal Investigator
  
  末原義之
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University

All 2017 2016

All Journal Article Presentation

[Journal Article] Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults2016
- Author(s)
  Takahiko Yasuda, Shinobu Tsuzuki, Masahito Kawazu, Fumihiko Hayakawa, Shinya Kojima, Toshihide Ueno, Naoto Imoto, Shinji Kohsaka, Akiko Kunita, Koichiro Doi, Toru Sakura, Toshiaki Yujiri, Eisei Kondo, Katsumichi Fujimaki, Yasunori Ueda, Yasutaka Aoyama, Shigeki Ohtake, Junko Takita, Eirin Sai, Masafumi Taniwaki, et al.
- Journal Title
  
  Nature genetics
  
  Volume : in press Pages : 569-574
- Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09472, KAKENHI-PROJECT-25860289, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-26461421, KAKENHI-PROJECT-16K09856, KAKENHI-PROJECT-25461432
[Journal Article] Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors2016
- Author(s)
  Ishii M, Akaike K, Suehara Y, Mukaihara K, Kubota K , Kohsaka S, Okubo T, Mitani K, Mogushi K, Takagi T, Kaneko K, Yao T, Saito T.
- Journal Title
  
  Modern Pathology.
  
  Volume : 29 Pages : 1424-1432
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26893267, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26670286, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070
[Journal Article] Expression of F-actin-capping protein subunit beta is associated with cell growth and motility in epithelioid sarcoma.2016
- Author(s)
  Mukaihara K, Suehara Y*, Kohsaka S, Kubota D, Toda-Ishii M, Akaike K, Fujimura T, Kobayashi E, Yao T, Ladanyi, M, Kaneko K, Saito T.
- Journal Title
  
  BMC cancer.
  
  Volume : 16(1) Pages : 206-206
- Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353
[Journal Article] Protein expression profiling of giant cell tumors of bone treated with denosumab.2016
- Author(s)
  Mukaihara K, Suehara Y, Kohsaka S, Kubota D, Akaike K, Ishii M, Fujimura T, Okubo T, Takagi T, Yao T, Kaneko K, Ladanyi M, Saito T.
- Journal Title
  
  PLoS ONE
  
  Volume : 11
- Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893267, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-26670286, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070, KAKENHI-PROJECT-15KK0353
[Journal Article] LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.2016
- Author(s)
  Takanobu Jotatsu, Shigehiro Yagishita, Ken Tajima, Fumiyuki Takahashi, Kaoru Mogushi, Moulid Hidayat, Aditya Wirawan, Ryo Ko, Ryota Kanemaru, Naoko Shimada, Keiko Mitani, Tsuyoshi Saito, Kazuya Takamochi, Kenji Suzuki, Shinji Kohsaka, Shinya Kojima, Hiroshi Mukae, Kazuhiro Yatera, Kazuhisa Takahashi.
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume : 9 Pages : 86-94
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02676
[Presentation] Proteomic approaches reveal that inhibition of the IRE1/XBP1 pathway reduces tumor growth in Ewing's sarcoma.2017
- Author(s)
  Tanabe Y, Suehara Y, Kohsaka S, Mukaihara K, Kubota D, Akaike K, Ishii M, Kazuno S, Mineki R, Kaneko K, Ladanyi M, Saito T.
- Organizer
  the 63th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  San Diego, USA
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] Proteomics analysis of characteristic histological changes with Denosumab treatment in giant cell tumors of bone.2017
- Author(s)
  SueharaY, Mukaihara K, TanabeY, Kohsaka S, Kazuno S, Ishii M, Akaike K, Kubota D, Kaneko K, Saito T.
- Organizer
  the 63th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  San Diego, USA
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] The Regulation of Malignant Transformation by PPP2R1A in Alveolar Rhabdomyosarcoma Based On A Proteomic Approach Corresponding To The PAX3/FOXO1 Fusion Gene.2016
- Author(s)
  Akaike K, Suehara Y, Kohsaka S, Mukaihara K, Ishii M, Kubota D, Tanabe Y, Kazuno S, Mineki R, Fujimura T, Kaneko K, Ladanyi M, Saito T.
- Organizer
  Connective Tissue Oncology Society, 21th Annual Meeting,
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] Protein Expression Profiles Corresponding To Histological Changes With Denosumab Treatment in Giant Cell Tumors of Bone.2016
- Author(s)
  Suehara Y, Mukaihara K, Tanabe Y, Kohsaka S, Kazuno S, Ishii M, Akaike K, Kubota D, Kaneko K, Saito T.
- Organizer
  Connective Tissue Oncology Society, 21th Annual Meeting,
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] Microsatellite instability analysis using the Promega panel in lung adenocarcinoma.2016
- Author(s)
  Takamochi K, Takahashi F, Suehara Y, Kitano S, Sato E, Kohsaka S, Hayashi T, Mano H, Suzuki K.
- Organizer
  Chest Annual Meeting 2016
- Place of Presentation
  Los Angels, USA
- Year and Date
  2016-10-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670
[Presentation] Proteomic approaches revealed inhibition of IRE1/XBP1 pathway reduces tumor growths in Ewing's sarcomas.2016
- Author(s)
  Tanabe Y, Suehara Y, Kohsaka S, Mukaihara K, Kubota D, Akaike K, Ishii M, Kazuno S, Mineki R, Kaneko K, Ladanyi M, Saito T.
- Organizer
  Connective Tissue Oncology Society, 21th Annual Meeting,
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15670

1. 末原義之 (70509405)

# of Collaborated Projects : 2results

# of Collaborated Products : 9results
2. 松田浩一 (90401257)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
3. 中村卓郎 (00180373)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. 松本嘉寛 (10346794)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. 植田幸嗣 (10509110)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
6. 穴澤卯圭 (20245525)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 比留間徹 (20254188)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. 五嶋孝博 (20272544)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. 河野博隆 (20345218)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 小林寛 (20407951)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
11. 岡本健 (30414113)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 河本旭哉 (30420558)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. 平賀博明 (30501530)

# of Collaborated Projects : 1results

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14. 土屋弘行 (40227434)

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15. 秋山達 (40376471)

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16. 元井亨 (50291315)

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17. 西田佳弘 (50332698)

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# of Collaborated Products : 0results
18. 中川英刀 (50361621)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. 小田義直 (70291515)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
20. 國定俊之 (80346428)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. 松原大祐 (80415554)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. 山口類 (90380675)

# of Collaborated Projects : 1results

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23. 綿貫宗則 (90451575)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. 川井章 (90252965)

# of Collaborated Projects : 1results

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25. 吉川秀樹 (60191558)

# of Collaborated Projects : 1results

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26. 中山ロバート (00365298)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
27. 米本司 (50506318)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
28. 阿江啓介 (20376726)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
29. 堀内圭輔 (30327564)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
30. 岩田慎太郎 (90549685)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
31. 小林英介 (40365292)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
32. Kunita Akiko

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
33. YUJIRI Toshiaki

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
34. Taniwaki Masafumi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
35. Ishii Midori

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
36. Mukaihara Kenta

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
37. Akaike Keisuke

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
38. Saito Tsuyoshi

# of Collaborated Projects : 0results

# of Collaborated Products : 3results
39. OKUBO TAKETO

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
40. FUJIMURA Tsutomu

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
41. 早川文彦

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
42. 窪田大介

# of Collaborated Projects : 0results

# of Collaborated Products : 3results

Kohsaka Shinji 高阪 真路

Research Projects

Research Products

Co-Researchers

肉腫融合遺伝子による発がんメカニズムの統合的探索Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

骨軟部腫瘍における診断マーカーの同定と腫瘍概念の再構築を目指した融合遺伝子の探索Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

「希少癌」骨軟部腫瘍のチロシンキナーゼ遺伝子転写変異体の探索Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults2016

Author(s)

Journal Title

Data Source

[Journal Article] Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors2016

Author(s)

Journal Title

Data Source

[Journal Article] Expression of F-actin-capping protein subunit beta is associated with cell growth and motility in epithelioid sarcoma.2016

Author(s)

Journal Title

Data Source

[Journal Article] Protein expression profiling of giant cell tumors of bone treated with denosumab.2016

Author(s)

Journal Title

Data Source

[Journal Article] LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.2016

Author(s)

Journal Title

Data Source

[Presentation] Proteomic approaches reveal that inhibition of the IRE1/XBP1 pathway reduces tumor growth in Ewing's sarcoma.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Proteomics analysis of characteristic histological changes with Denosumab treatment in giant cell tumors of bone.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The Regulation of Malignant Transformation by PPP2R1A in Alveolar Rhabdomyosarcoma Based On A Proteomic Approach Corresponding To The PAX3/FOXO1 Fusion Gene.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Protein Expression Profiles Corresponding To Histological Changes With Denosumab Treatment in Giant Cell Tumors of Bone.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Microsatellite instability analysis using the Promega panel in lung adenocarcinoma.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Proteomic approaches revealed inhibition of IRE1/XBP1 pathway reduces tumor growths in Ewing's sarcomas.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Kohsaka Shinji 高阪真路