WAKAHARA Keiko 若原恵子

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Wakahara Keiko 若原恵子

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Researcher Number	00631433
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 客員研究者
Affiliation (based on the past Project Information) *help	2024: 名古屋大学, 医学系研究科, 客員研究者 2020 – 2023: 名古屋大学, 医学部附属病院, 講師 2017 – 2018: 名古屋大学, 医学部附属病院, 講師 2015: 名古屋大学, 医学部附属病院, 病院講師 2014: 名古屋大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Respiratory surgery
Keywords	Principal Investigator 好塩基球 / 気管支喘息 / treatable traits / united airway disease / 上気道細菌叢 / 末梢ヘルパーT細胞 / 関節リウマチ / COPD / 慢性副鼻腔炎 / 好酸球性肺疾患 … More / アレルギー性肺疾患 / 2型炎症 / 2型自然リンパ球 / 好酸球性炎症 / 樹状細胞 / 炎症性樹状細胞 … More Except Principal Investigator 肺線維症 / マクロファージ / ミトコンドリア / DAMPS / 急性増悪 / ミトコンドリアDNA / 診断 / 人工知能 / 血管内皮細胞 / マイクロCT / 金ナノ粒子 / 線維芽細胞 / 分子標的治療薬 / 抗癌剤 / 肺癌 / 低分子化合物 / がん幹細胞 / 肺がん Less

上気道炎症複合的プロファイルと下気道疾患・好塩基球の役割とtreatable traitsの探索Principal Investigator
- Principal Investigator
  
  若原恵子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
好塩基球を介した2型炎症調節機構の解明ーアレルギー性・好酸球性肺疾患と肺恒常性Principal Investigator
- Principal Investigator
  
  若原恵子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagoya University
間質性肺炎急性増悪病態における新規病的微小環境因子・ミトコンドリアＤＮＡの役割
- Principal Investigator
  
  阪本考司
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
Immune-pathological diagnostic artificial intelligence development research for pulmonary fibrosis using fibrotic foci-specific enhanced micro-CT
- Principal Investigator
  
  Hashimoto Naozumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Fujita Health University
  Nagoya University
Basophils as potential refractory factors and biomarkers for chronic airway inflammationPrincipal Investigator
- Principal Investigator
  
  Wakahara Keiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
Analysis of bronchial asthma onset/exacerbation mechanism based on inflammatory dendritic cells and basophils.Principal Investigator
- Principal Investigator
  
  Wakahara Keiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nagoya University
Identification of cancer initiating cell factors and an attempt of drug development
- Principal Investigator
  
  SUZUKI Motoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Nagoya University

All 2022 2021 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Overexpression of bone morphogenetic protein receptor type 2 suppresses transforming growth factor β-induced profibrotic responses in lung fibroblasts2022
- Author(s)
  Fukihara Jun、Maiolo Suzanne、Kovac Jessica、Sakamoto Koji、Wakahara Keiko、Hashimoto Naozumi、Reynolds Paul N.
- Journal Title
  
  Experimental Lung Research
  
  Volume: 48 Issue: 1 Pages: 35-51
- DOI
  10.1080/01902148.2021.2024301
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08202, KAKENHI-PROJECT-20K21599, KAKENHI-PROJECT-18K15948
[Journal Article] Fibroblasts positive for meflin have anti-fibrotic properties in pulmonary fibrosis2021
- Author(s)
  Nakahara Y, Hashimoto N, Sakamoto K, Enomoto A, Adams TS, Yokoi T, Omote N, Poli S, Ando A, Wakahara K, Suzuki A, Inoue M, Hara A, Mizutani Y, Imaizumi K, Kawabe T, Rosas IO, Takahashi M, Kaminski N, Hasegawa Y.
- Journal Title
  
  European Respiratory Journal
  
  Volume: 58 Issue: 6 Pages: 2003397-2003397
- DOI
  10.1183/13993003.03397-2020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07824, KAKENHI-PROJECT-21K08202, KAKENHI-PROJECT-20K21599, KAKENHI-PROJECT-18K15948, KAKENHI-PROJECT-20H03467
[Journal Article] Longitudinal changes in pulmonary function and respiratory impedance of rheumatoid arthritis2019
- Author(s)
  Isobe Y, Ito S, Matsuda T, Iwano S, Uchida A, Takahashi N, Kojima T, Wakahara K, Yamaguchi E, Hasegawa Y
- Journal Title
  
  Repir Physiol Neurobiol
  
  Volume: 261 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08173
[Journal Article] 重症喘息と気道炎症好酸球性炎症を中心として2018
- Author(s)
  若原恵子
- Journal Title
  
  日本職業・環境アレルギー学会雑誌
  
  Volume: 25 Pages: 37-45
- NAID
  40021621019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08173
[Journal Article] Airway basophils are increased and activated in eosinophilic asthma2017
- Author(s)
  Suzuki Y, Wakahara K, Nishio T, Ito S, Hasegawa Y
- Journal Title
  
  Allergy
  
  Volume: 72(10) Issue: 10 Pages: 1532-1539
- DOI
  10.1111/all.13197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09549
[Journal Article] Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.2016
- Author(s)
  Suzuki M, et al.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 126 Issue: 1 Pages: 254-265
- DOI
  10.1172/jci79775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460203, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-15K12527, KAKENHI-PUBLICLY-26110717, KAKENHI-PROJECT-26889060, KAKENHI-PROJECT-25460217, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-25289299, KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-25250017, KAKENHI-PLANNED-15H05910, KAKENHI-PROJECT-16H04767
[Presentation] Mixed cellular inflammation is increased in adult asthma with severe chronic rhinosinusitis2019
- Author(s)
  Nishio T, Wakahara K, Suzuki Y, Majima S, Nishio N, Teranishi M, Sone M, Hasegawa Y
- Organizer
  American Academy of Allergy Asthma & Immunology annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08173
[Presentation] 気道炎症に対する細胞生物学的アプローチ　好塩基球2018
- Author(s)
  若原恵子
- Organizer
  第24回国際喘息学会日本・北アジア部会
- Data Source
  KAKENHI-PROJECT-18K08173
[Presentation] Periostin levels in chronic obstructive pulmonary disease (COPD)2018
- Author(s)
  Nakamura S, Wakahara K, Majima S, Nishio T, Suzuki Y, Shiraki A, Abe T, Shindoh J, Sashio T, Ono J, Izuhara K, Hasegawa Y
- Organizer
  European Respiratory Society Annual Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08173
[Presentation] Increasing sputum basophils is a marker for eosinophil-dominant airway inflammation in adult asthma2018
- Author(s)
  Wakahara K, Nishio T, Suzuki Y, Majima S, Nakamura S, Hasegawa Y
- Organizer
  European Respiratory Society Annual Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08173
[Presentation] Flow cytometric analysis of induced sputum to evaluate eosinophilic inflammation2017
- Author(s)
  Wakahara K, Suzuki Y, NIshio T, Majima S, Hasegawa Y
- Organizer
  アジア太平洋呼吸器学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09549
[Presentation] Airway Basophils Are Activated and Associated with Eosinophilic Inflammation in Asthmatic Patients2016
- Author(s)
  Yoshihiro Suzuki, Keiko Wakahara, Tomoko Nishio, Satoru Ito, Yoshinori Hasegawa
- Organizer
  アメリカアレルギー学会
- Place of Presentation
  ロサンゼルス, アメリカ
- Year and Date
  2016-03-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09549

1. Hashimoto Naozumi (30378020)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 阪本考司 (00635633)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. SUZUKI Motoshi (80236017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. FUKUI Takayuki (70463198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KATO Sei-ichi (30584669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Nishida Atsushi (80130029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中村彰太 (20612849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 古川大記 (30837654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 芳川豊史 (00452334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 猪股弥生 (90469792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 齋藤研 (60964880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUZUKI Yoshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. NISHIO Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. KAWABE Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WAKAHARA Keiko 若原 恵子

Wakahara Keiko 若原 恵子

Research Projects

Research Products

Co-Researchers

上気道炎症複合的プロファイルと下気道疾患・好塩基球の役割とtreatable traitsの探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

好塩基球を介した2型炎症調節機構の解明ーアレルギー性・好酸球性肺疾患と肺恒常性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

間質性肺炎急性増悪病態における新規病的微小環境因子・ミトコンドリアＤＮＡの役割

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Immune-pathological diagnostic artificial intelligence development research for pulmonary fibrosis using fibrotic foci-specific enhanced micro-CT

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basophils as potential refractory factors and biomarkers for chronic airway inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of bronchial asthma onset/exacerbation mechanism based on inflammatory dendritic cells and basophils.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of cancer initiating cell factors and an attempt of drug development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Overexpression of bone morphogenetic protein receptor type 2 suppresses transforming growth factor β-induced profibrotic responses in lung fibroblasts2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibroblasts positive for meflin have anti-fibrotic properties in pulmonary fibrosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Longitudinal changes in pulmonary function and respiratory impedance of rheumatoid arthritis2019

Author(s)

Journal Title

Data Source

[Journal Article] 重症喘息と気道炎症 好酸球性炎症を中心として2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Airway basophils are increased and activated in eosinophilic asthma2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Mixed cellular inflammation is increased in adult asthma with severe chronic rhinosinusitis2019

Author(s)

Organizer

Data Source

WAKAHARA Keiko 若原恵子

Wakahara Keiko 若原恵子

[Journal Article] 重症喘息と気道炎症好酸球性炎症を中心として2018

[Presentation] 気道炎症に対する細胞生物学的アプローチ　好塩基球2018