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Hashimoto Naozumi  橋本 直純

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… Alternative Names

橋本 直純  ハシモト ナオズミ

HASHIMOTO Naozumi  橋本 直純

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Researcher Number 30378020
Other IDs
Affiliation (Current) 2022: 藤田医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2020 – 2021: 名古屋大学, 医学系研究科, 准教授
2014 – 2016: 名古屋大学, 医学部附属病院, 講師
2012 – 2014: 名古屋大学, 医学部附属病院, 病院講師
2007 – 2012: Nagoya University, 医学部附属病院, 助教
2011: 名古屋大学, 医学系研究科, 助教 … More
2008: Nagoya University, 医学部・附属病院, 助教
2006: 名古屋大学, 大学院医学系研究科, COE研究員
2005: 名古屋大学, 大学院・医学系研究科, COE研究員 Less
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine / Medium-sized Section 53:Organ-based internal medicine and related fields
Except Principal Investigator
Respiratory organ internal medicine / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 53030:Respiratory medicine-related
Keywords
Principal Investigator
線維芽細胞 / 肺線維症 / 線維症 / 再生医療 / 呼吸器病学 / 血管内皮細胞 / PTEN / 微小環境 / 上皮間葉系移行 / 骨髄幹細胞 … More / 形質転換 / 再生医学 / 移植・再生医 / 細胞・組織 / 移植・再生医療 / 血管内皮間葉系細胞転換 / 低酸素 / 肺癌 / TGFbeta / TGFbe-ta / Fibrosis / Lung Cancer / 分子細胞尾呼吸器学 / 細胞内導入デリバリーシステム / 上皮細胞 / 金ナノ粒子 / マイクロCT / 人工知能 / 診断 … More
Except Principal Investigator
肺癌 / 上皮間葉系細胞転換 / EMT / Notch受容体 / 癌の転移 / 血管内皮細胞 / アポトーシス / ルイス肺癌 / 循環血液中癌細胞 / マイクロフルイディクス / EMT関連遺伝子 / ZEB1 / Twist遺伝子 / 癌転移 / 上皮細胞接着分子 / 呼吸器病学 / 肺がん / リンパ節 / HIF1α / VEGF / 内科 / 呼吸器内科 / リンパ節転移 / 肺の再生 / 低酸素 / PTEN / 組織微小環境 / 上皮間葉系移行 / 肺構成細胞 / 再生医療 / 肺傷害 / 好塩基球 / 2型自然リンパ球 / 2型炎症 / アレルギー性肺疾患 / 好酸球性肺疾患 / ミトコンドリア / 肺線維症 / 急性増悪 / マクロファージ Less
  • Research Projects

    (12 results)
  • Research Products

    (103 results)
  • Co-Researchers

    (21 People)
  •  好塩基球を介した2型炎症調節機構の解明ーアレルギー性・好酸球性肺疾患と肺恒常性

    • Principal Investigator
      若原 恵子
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Nagoya University
  •  間質性肺炎急性増悪病態における新規病的微小環境因子・ミトコンドリアDNAの役割

    • Principal Investigator
      阪本 考司
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Nagoya University
  •  Immune-pathological diagnostic artificial intelligence development research for pulmonary fibrosis using fibrotic foci-specific enhanced micro-CTPrincipal Investigator

    • Principal Investigator
      橋本 直純
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Nagoya University
  •  The development of new therapy for pulmonary fibrosis by using exogenous protein delivery system mimicked biological mechanismPrincipal Investigator

    • Principal Investigator
      HASHIMOTO NAOZUMI
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagoya University
  •  New therapeutic strategy targeting phosphorylation sites of the PTEN C-terminus for lung epithelial/endothelial-mesenchymal transitionPrincipal Investigator

    • Principal Investigator
      HASHIMOTO Naozumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagoya University
  •  Molecular Target of Regenerative Pulmonary Medicine for Chronic Obstructive Pulmonary Disease

    • Principal Investigator
      HASEGAWA Yoshinori
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagoya University
  •  Exploration of new therapy and diagnosis in lymph metastasis of lung cancer based on theprofile of lymphangiogenic-related genes expression

    • Principal Investigator
      IMAIZUMI Kazuyoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Fujita Health University
      Nagoya University
  •  Analysis of cancer metastasis using circulating tumor cells purified by micro-fluidics techniques

    • Principal Investigator
      HASEGAWA Yoshinori
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagoya University
  •  The establishment of therapeutic strategy for pulmonary fibrosis and pulmonary hypertension in targeting endothelial-mesenchymal transitionPrincipal Investigator

    • Principal Investigator
      HASHIIMO Naozumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagoya University
  •  Lung regenerative medicine using fibroblasts-derived stem cell line with stem cell inducing factorsPrincipal Investigator

    • Principal Investigator
      HASHIMOTO Naozumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagoya University
  •  上皮間葉系細胞転換(EMT)分子(NOTCH)を標的にした固形癌制御の研究

    • Principal Investigator
      長谷川 好規
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagoya University
  •  線維芽細胞の起源再考からの肺線維症の病態解明Principal Investigator

    • Principal Investigator
      橋本 直純
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nagoya University

All 2022 2021 2020 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-192022

    • Author(s)
      Omote Norihito、Kanemitsu Yoshihiro、Inoue Takahiro、Yonezawa Toshiyuki、Ichihashi Takuji、Shindo Yuichiro、Sakamoto Koji、Ando Akira、Suzuki Atsushi、Niimi Akio、Ito Satoru、Imaizumi Kazuyoshi、Hashimoto Naozumi
    • Journal Title

      Internal Medicine

      Volume: 61 Issue: 2 Pages: 233-236

    • DOI

      10.2169/internalmedicine.8163-21

    • NAID

      130008141771

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08517, KAKENHI-PROJECT-21K08202
  • [Journal Article] Overexpression of bone morphogenetic protein receptor type 2 suppresses transforming growth factor β-induced profibrotic responses in lung fibroblasts2022

    • Author(s)
      Fukihara Jun、Maiolo Suzanne、Kovac Jessica、Sakamoto Koji、Wakahara Keiko、Hashimoto Naozumi、Reynolds Paul N.
    • Journal Title

      Experimental Lung Research

      Volume: 48 Pages: 35-51

    • DOI

      10.1080/01902148.2021.2024301

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08202, KAKENHI-PROJECT-18K15948
  • [Journal Article] Oxytocin receptor is a promising therapeutic target of malignant mesothelioma2021

    • Author(s)
      Oxytocin receptor is a promising therapeutic target of malignant mesothelioma. Kodama Y, Tanaka I, Sato T, Hori K, Gen S, Morise M, Matsubara D, Sato M, Sekido Y, Hashimoto N.
    • Journal Title

      Cancer Science

      Volume: 112 Pages: 3520-3532

    • DOI

      10.1111/cas.15025

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22617, KAKENHI-PROJECT-19H03527, KAKENHI-PROJECT-20K21599
  • [Journal Article] Long noncoding RNA TINCR is a novel regulator of human bronchial epithelial cell differentiation state2021

    • Author(s)
      Omote N, Sakamoto K, Li Q, Schupp JC, Adams T, Ahangari F, Chioccioli M, DeIuliis G, Hashimoto N, Hasegawa Y, Kaminski N.
    • Journal Title

      Physiological Reports

      Volume: 9

    • DOI

      10.14814/phy2.14727

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15948, KAKENHI-PROJECT-20K21599
  • [Journal Article] Serum mitochondrial DNA predicts the risk of acute exacerbation and progression of idiopathic pulmonary fibrosis.2021

    • Author(s)
      Sakamoto Koji、Furukawa Taiki、Yamano Yasuhiko、Kataoka Kensuke、Teramachi Ryo、Walia Anjali、Suzuki Atsushi、Inoue Masahide、Nakahara Yoshio、Ryu Changwan、Hashimoto Naozumi、Kondoh Yasuhiro
    • Journal Title

      Eur Respir J.

      Volume: 57 Pages: 2001346-2001346

    • DOI

      10.1183/13993003.01346-2020

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21599, KAKENHI-PROJECT-18K15948
  • [Journal Article] Size and surface modification of silica nanoparticles affect the severity of lung toxicity by modulating endosomal ROS generation in macrophages.2021

    • Author(s)
      Masahide Inoue, Koji Sakamoto, Atsushi Suzuki, Shinya Nakai, Akira Ando, Yukihiko Shiraki, Yoshio Nakahara, Mika Omura, Atsushi Enomoto, Ikuhiko Nakase, Makoto Sawada, Naozumi Hashimoto
    • Journal Title

      Part Fibre Toxicol.

      Volume: 18 Pages: 21-21

    • DOI

      10.1186/s12989-021-00415-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K20463, KAKENHI-PROJECT-21K08202, KAKENHI-PROJECT-20K21599, KAKENHI-PROJECT-18K15948
  • [Journal Article] Fibroblasts positive for meflin have anti-fibrotic property in pulmonary fibrosis.2021

    • Author(s)
      Nakahara Y, Hashimoto N, Sakamoto K, Enomoto A, Adams TS, Yokoi T, Omote N, Poli S, Ando A, Wakahara K, Suzuki A, Inoue M, Hara A, Mizutani Y, Imaizumi K, Kawabe T, Rosas IO, Takahashi M, Kaminski N, Hasegawa Y.
    • Journal Title

      European Respiratory Journal

      Volume: 58 Pages: 2003397-2003397

    • DOI

      10.1183/13993003.03397-2020

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07824, KAKENHI-PROJECT-21K08202, KAKENHI-PROJECT-20K21599, KAKENHI-PROJECT-18K15948
  • [Journal Article] Clinical burden of immune checkpoint inhibitor-induced pneumonitis.2020

    • Author(s)
      Sakamoto Koji、Fukihara Jun、Morise Masahiro、Hashimoto Naozumi
    • Journal Title

      Respir Investig.

      Volume: 58 Pages: 305-319

    • DOI

      10.1016/j.resinv.2020.05.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07910, KAKENHI-PROJECT-20K21599, KAKENHI-PROJECT-18K15948
  • [Journal Article] Probable usual interstitial pneumonia pattern on chest CT: is it sufficient for a diagnosis of idiopathic pulmonary fibrosis?2020

    • Author(s)
      Fukihara Jun、Kondoh Yasuhiro、Brown Kevin K.、Kimura Tomoki、Kataoka Kensuke、Matsuda Toshiaki、Yamano Yasuhiko、Suzuki Atsushi、Furukawa Taiki、Sumikawa Hiromitsu、Takahashi Osamu、Johkoh Takeshi、Tanaka Tomonori、Fukuoka Junya、Hashimoto Naozumi、Hasegawa Yoshinori
    • Journal Title

      European Respiratory Journal

      Volume: 55 Pages: 1802465-1802465

    • DOI

      10.1183/13993003.02465-2018

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21599
  • [Journal Article] Impact of thin-section computed tomography-determined combined pulmonary fibrosis and emphysema on outcomes among patients with resected lung cancer2016

    • Author(s)
      Hashimoto N, Iwano S, Kawaguchi K, Fukui T, Fukumoto K, Nakamura S, Mori S, Sakamoto K, Wakai K, Yokoi K, Hasegawa Y.
    • Journal Title

      Ann Thorac Surg

      Volume: 102 Pages: 440-447

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Journal Article] Clinical impact of the lower limit of normal of FEV1/FVC on survival in lung cancer patients undergoing thoracic surgery2016

    • Author(s)
      Matsuzaki A, Hashimoto N, Okachi S, Taniguchi T, Kawaguchi K, Fukui T, Wakai K, Yokoi K, Hasegawa Y.
    • Journal Title

      Respir Investig

      Volume: 54 Pages: 184-192

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Journal Article] Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers2016

    • Author(s)
      Kohnoh T, Hashimoto N, Ando A, Sakamoto K, Miyazaki S, Aoyama D, Kusunose M, Kimura M, Omote N, Imaizumi K, Kawabe T, Hasegawa Y.
    • Journal Title

      Cancer Cell International

      Volume: 16 Pages: 33-42

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Journal Article] Antineutrophil Cytoplasmic Antibody-associated Vasculitis Superimposed on Infection-related Glomerulonephritis Secondary to Pulmonary Mycobacterium avium Complex Infection2016

    • Author(s)
      Asano S, Mizuno S, Okachi S, Aso H, Wakahara K, Hashimoto N, Ito S, Kozaki Y, Katsuno T, Maruyama S, Hasegawa Y.
    • Journal Title

      Intern Med

      Volume: 55 Pages: 2439-2445

    • NAID

      130005262546

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Journal Article] Factors Affecting the Diagnostic Yield of Transbronchial Biopsy Using Endobronchial Ultrasonography with a Guide Sheath in Peripheral Lung Cancer2016

    • Author(s)
      Okachi S, Imai N, Imaizumi K, Iwano S, Ando M, Hase T, Aso H, Morise M, Wakahara K, Ito S, Hashimoto N, Sato M, Kondo M, Hasegawa Y.
    • Journal Title

      Intern Med

      Volume: 55 Pages: 1705-1712

    • NAID

      130005161019

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Journal Article] Bronchus sign on thin-section computed tomography is a powerful predictive factor for successful transbronchial biopsy using endobronchial ultrasound with a guide sheath for small peripheral lung lesions: a retrospective observational study.2015

    • Author(s)
      Minezawa T, Okamura T, Yatsuya H, Yamamoto N, Morikawa S, Yamaguchi T, Morishita M, Niwa Y, Takeyama T, Mieno Y, Hoshino T, Uozu S, Goto Y, Hayashi M, Isogai S, Matsuo M, Nakanishi T, Hashimoto N, Okazawa M, Imaizumi K.
    • Journal Title

      BMC Medical Imaging

      Volume: 21 Pages: 21-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Journal Article] Risk stratification by the lower limit of normal of FEV1/FVC for postoperative outcomes in patients with COPD undergoing thoracic surgery.2015

    • Author(s)
      Osuka S, Hashimoto N, Sakamoto K, Wakai K, Yokoi K, Hasegawa Y.
    • Journal Title

      Respir Investig

      Volume: 53 Pages: 117-123

    • DOI

      10.1016/j.resinv.2015.01.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Journal Article] Direct regulation of TGFβ-induced EMT by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells.2015

    • Author(s)
      Kusunose M, Hashimoto N, Kimura M, Ogata R, Aoyama D, Sakamoto K, Miyazaki S, Ando A, Omote N, Imaizumi K, Kawabe T, Hasegawa Y.
    • Journal Title

      Cancer Science

      Volume: 106 Pages: 1693-1704

    • DOI

      10.1111/cas.12831

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09198, KAKENHI-PROJECT-15K15322
  • [Journal Article] Evaluation of emphysema using three-dimensional computed tomography: association with postoperative complications in lung cancer patients.2015

    • Author(s)
      Kawakami K, Iwano S, Hashimoto N, Hasegawa Y, Naganawa S.
    • Journal Title

      Nagoya J Med Sci

      Volume: 77 Pages: 113-122

    • NAID

      120005549557

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Journal Article] Factors secreted from dental pulp stem cells show multifaceted benefits for treating acute respiratory distress syndrome in mice.2015

    • Author(s)
      Wakayama H, Hashimoto N, Matsushita Y, Matsubara K, Yamamoto N, Hasegawa Y, Ueda M, Yamamoto A
    • Journal Title

      Cytotherapy

      Volume: 17 Pages: 1119-1129

    • DOI

      10.1016/j.jcyt.2015.04.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Journal Article] Synergistic Effect of Bolus Exposure to Zinc Oxide Nanoparticles on Bleomycin-Induced Secretion of Pro-Fibrotic Cytokines without Lasting Fibrotic Changes in Murine Lungs.2014

    • Author(s)
      Wu W, Ichihara G, Hashimoto N, Hasegawa Y, Hayashi Y, Tada-Oikawa S, Suzuki Y, Chang J, Kato M, D'Alessandro-Gabazza CN, Gabazza EC, Ichihara S.
    • Journal Title

      Int J Mol Sci.

      Volume: 16 Pages: 660-676

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Lobar analysis of collapsibility indices to assess functional lung volumes in COPD patients2014

    • Author(s)
      Kitano M, Iwano S, Hashimoto N, Matsuo K, Hasegawa Y, Naganawa S
    • Journal Title

      Int J Chron Obstruct Pulmon Dis.

      Volume: 9 Pages: 1347-1356

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Clinical impact of prevalence and severity of COPD on the decision-making process for therapeutic management of lung cancer patients.2014

    • Author(s)
      Hashimoto N, Matsuzaki A, Okada Y, Imai N, Iwano S, Wakai K, Imaizumi K, Yokoi K, Hasegawa Y.
    • Journal Title

      BMC Pulm Med

      Volume: 14 Pages: 14-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Protective effects of intratracheally administered quercetin on lipopolysaccharide-induced acute lung injury.2014

    • Author(s)
      Takashima K, Matsushima M, Hashimoto K, Nose H, Sato M, Hashimoto N, Hasegawa Y, Kawabe T.
    • Journal Title

      Respir Res.

      Volume: 15 Pages: 150-150

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Prospective analysis of efficacy and safety of an individualized-midazolam-dosing protocol for sedation during prolonged bronchoscopy.2014

    • Author(s)
      Ogawa T, Imaizumi K, Hashimoto I, Shindo Y, Imai N, Uozu S, Shimokata T, Ito S, Hashimoto N, Sato M, Kondo M, Hasegawa Y
    • Journal Title

      Respir Investig

      Volume: 52 Pages: 153-159

    • DOI

      10.1016/j.resinv.2013.09.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Involvement of TGFβ-induced phosphorylation of the PTEN C-terminus on TGFβ-induced acquisition of malignant phenotypes in lung cancer cells.2013

    • Author(s)
      Aoyama D#, Hashimoto N#*, Sakamoto K, Kohnoh T, Kusunose M, Kimura M, Ogata R, Imaizumi K, Kawabe T, Hasegawa Y.
    • Journal Title

      Plos One

      Volume: 8(11)

    • DOI

      10.1371/journal.pone.0081133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] An aqueous fraction of Sauropus androgynus might be responsible for bronchiolitis obliterans.2013

    • Author(s)
      Hashimoto I, Imaizumi K, Hashimoto N, Furukawa H, Noda Y, Kawabe T, Honda T, Ogawa T, Matsuo M, Imai N, Ito S, Sato M, Kondo M, Shimokata K, Hasegawa Y
    • Journal Title

      Respirology

      Volume: 18(2) Pages: 340-347

    • DOI

      10.1111/j.1440-1843.2012.02286.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590856, KAKENHI-PROJECT-22590857
  • [Journal Article] Endobronchial ultrasound transbronchial needle aspiration in older people2013

    • Author(s)
      Okachi S, Imai N, Imaizumi K, Hase T,Shindo Y, Sakamoto K, Aso H, Wakahara K,Hashimoto I, Ito S, Hashimoto N, Sato M,Kondo M, Hasegawa Y.
    • Journal Title

      Geriatr Gerontol Int

    • DOI

      10.1111/ggi.12043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] An aqueous fraction of Sauropus androgynus might be responsible for bronchiolitis obliterans.2013

    • Author(s)
      Hashimoto I, Imaizumi K, Hashimoto N,Furukawa H, Noda Y, Kawabe T, Honda T,Ogawa T, Matsuo M, Imai N, Ito S, Sato M,Kondo M, Shimokata K, Hasegawa Y.
    • Journal Title

      Respirology

      Volume: 18(2) Pages: 340-347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Detection of loci for allergic asthma using SMXA recombinant inbred strains of mice2013

    • Author(s)
      Ohno T, Okamoto M, Hara T, Hashimoto N,Imaizumi K, Matsushima M, Nishimura M,Shimokata K, Hasegawa Y, Kawabe T
    • Journal Title

      Immunogenetics

      Volume: 65(1) Pages: 17-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Acute exacerbation of IPF following diagnostic bronchoalveolar lavage procedures.2012

    • Author(s)
      Sakamoto K, Taniguchi H, Kondoh Y, Wakai K, Kimura T, Kataoka K, Hashimoto N,Nishiyama O, Hasegawa Y
    • Journal Title

      Respir Med

      Volume: 106(3) Pages: 436-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Acute exacerbation of IPF following diagnostic broncho alveolar lavage procedures2012

    • Author(s)
      Sakamoto K, Taniguchi H, Kondoh Y, Wakai K, Kimura T, Kataoka K, Hashimoto N, Nishiyama O, Hasegawa Y.
    • Journal Title

      Respir Med

      Pages: 436-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Involvement of the transcription factor twist in phenotype alteration through epithelial-mesenchymal transition in lung cancer cells2012

    • Author(s)
      Nakashima H, Hashimoto N, Aoyama D, Kohnoh T, Sakamoto K, Kusunose M, Imaizumi K, Takeyama Y, Sato M, Kawabe T, Hasegawa Y
    • Journal Title

      Mol Carcinog

      Volume: 51 Pages: 400-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Journal Article] Quercetin protects against pulmonary oxidant stress via heme oxygenase-1 induction in lung epithelial cells2012

    • Author(s)
      Hayashi Y, Matsushima M, Nakamura T, Shibasaki M, Hashimoto N, Imaizumi K, Shimokata K, Hasegawa Y, Kawabe T
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 417(1) Pages: 169-174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Differential modulation of surfactant protein D under acute and persistent hypoxia in acute lung injury2012

    • Author(s)
      Sakamoto K, Hashimoto N, Kondoh Y, Imaizumi K, Aoyama D, Kohnoh T, Kusunose M, Kimura M, Kawabe T, Taniguchi H, Hasegawa Y
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol.

      Volume: 303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Journal Article] Quercetin protects against pulmonary oxidant stress via heme oxygenase-1 induction in lung epithelial cells2012

    • Author(s)
      Hayashi Y, Matsushima M, Nakamura T, Shibasaki M, Hashimoto N, Imaizumi K, Shimokata K, Hasegawa Y, KawabeT.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 417(1) Pages: 169-174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Inspiratory capacity as a preoperative assessment of patients undergoing thoracicsurgery2012

    • Author(s)
      Matsuo M, Hashimoto N, Usami N,Imaizumi K, Wakai K, Kawabe T, Yokoi K,Hasegawa Y
    • Journal Title

      Interact Cardiovasc Thorac Surg

      Volume: 14(5) Pages: 560-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Nongenomic effects of fluticasone propionate and budesonide on human airway anion secretion2012

    • Author(s)
      Naozumi Hashimoto (7番目)
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 47 Pages: 645-651

    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Involvement of the transcription factor twist in phenotype alteration through epithelial-mesenchymal transition in lung cancer cells2012

    • Author(s)
      Nakashima H, Hashimoto N, Aoyama D, Kohnoh T, Sakamoto K, Kusunose M, Imaizumi K, Takeyama Y, Sato M, Kawabe T, Hasegawa Y.
    • Journal Title

      Molecular Carcinogenesis

      Volume: E1 Pages: 400-10

    • DOI

      10.1002/mc.20802

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987, KAKENHI-PROJECT-22590856, KAKENHI-PROJECT-22590857, KAKENHI-PROJECT-23659431
  • [Journal Article] Febrile complications after endobronchial ultrasound-guided transbronchial needle aspiration for intra-pulmonary mass lesions of lung cancer-a series of 3 cases.2012

    • Author(s)
      Oguri T, Imai N, Imaizumi K, Elshazley M,Hashimoto I, Hashimoto N, Hasegawa Y
    • Journal Title

      Respir Investig

      Volume: 50(4) Pages: 162-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Interstitial pneumonia and nodular regenerative hyperplasia of the liver as initial manifestations of polyarteritis nodosa2012

    • Author(s)
      Tanaka I, Imaizumi K, Hashimoto I, Asai N,Yokoi T, Matsuno T, Hasegawa Y
    • Journal Title

      Intern Med.

      Volume: 51(6) Pages: 635-8

    • NAID

      130002061910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Non-Genomic Effects of Fluticasone Propionate and Budesonide on Human Airway Anion Secretion2012

    • Author(s)
      Mizutani T, Morise M, Ito Y, Hibino Y,Matsuno T, Ito S, Hashimoto N, Sato M, Kondo M, Imaizumi K, Hasegawa Y
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 47(5) Pages: 645-51

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Quercetin protects against pulmonary oxidant stress via heme oxygenase-1 induction in lung epithelial cells.2012

    • Author(s)
      Naozumi Hashimoto (5番目)
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 417 Pages: 169-174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Acute exacerbation of IPF following diagnostic bronchoalveolar lavage procedures.2012

    • Author(s)
      Naozumi Hashimoto (7番目)
    • Journal Title

      Respir Med.

      Volume: 106 Pages: 436-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Acute exacerbation of IPF following diagnostic bronchoalveolar lavage procedures2012

    • Author(s)
      Koji Sakamoto, Naozumi Hashimoto, 7番目
    • Journal Title

      Respir Med

      Volume: 106 Pages: 436-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Inspiratory capacity as a preoperative assessment of patients undergoing thoracic surgery2012

    • Author(s)
      Naozumi Hashimoto (2番目; equal contribution)
    • Journal Title

      Interact CardioVasc Thorac Surg

      Volume: 14 Pages: 560-564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Differential modulation of surfactant protein D under acute and persistent hypoxia in acute lung injury.2012

    • Author(s)
      Naozumi Hashimoto (2番目; equal contribution)
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol

      Volume: 303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Journal Article] Quercetin protects against pulmonary oxidant stress via hemeoxygenase-1 induction in lung epithelial cells2012

    • Author(s)
      Yuta Hayashi, Naozumi Hashimoto, 5番目
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 417 Pages: 169-174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Differential modulation of surfactant protein D under acute and persistent hypoxia in acute lung injury.2012

    • Author(s)
      Sakamoto K, Hashimoto N, Kondoh Y,Imaizumi K, Aoyama D, Kohnoh T,Kusunose M, Kimura M, Kawabe T,Taniguchi H, Hasegawa Y
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol

      Volume: 303(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Mesenchymal stem cells stably transduced with a dominant negative inhibitor of CCL2 greatly attenuate bleomycin-induced lung damage2011

    • Author(s)
      斎藤繁紀
    • Journal Title

      Am J Pathol.

      Volume: 179 Pages: 1088-1094

    • DOI

      10.1016/j.ajpath.2011.05.027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04711, KAKENHI-PROJECT-23591382, KAKENHI-PROJECT-23659431
  • [Journal Article] Attenuation of TGF-ss-Stimulated Collagen Production in Fibroblasts by Quercetin-InducedHO-1.2011

    • Author(s)
      Nakamura T, Matsushima M, Hayashi Y, Shibasaki M, Imaizumi K, Hashimoto N, Shimokata K, Hasegawa Y, Kawabe T.
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 44(5) Pages: 614-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Capsaicinoids regulate airway anion transporters through Rhokinase- and cAMP-dependent mechanisms2011

    • Author(s)
      Yoshitaka Hibino, Naozumi Hashimoto, 7番目
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 45 Pages: 684-691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Attenuation of TGF-ss-Stimulated Collagen Production in Fibroblasts by Quercetin-Induced HO-1.2011

    • Author(s)
      Nakamura T, Matsushima M, Hayashi Y,Shibasaki M, Imaizumi K, Hashimoto N, Shimokata K, Hasegawa Y, Kawabe T
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 44(5) Pages: 614-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Mesenchymal Stem Cells Stably Transduced with a Dominant CCL2 Greatly Attenuate Bleomycin-Induced Mesenchymal Stem Cells Stably Transduced with a Dominant-Negative Inhibitor ofCCL2 Greatly Attenuate Bleomycin-Induced Lung Damage2011

    • Author(s)
      Saito S, Nakayama T, Hashimoto N, Miyata Y, Egashira K, Nakao N, Nishiwaki S, Hasegawa M, Hasegawa Y, Naoe T.
    • Journal Title

      Am J Pathol

      Volume: 179(3) Pages: 1088-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Capsaicinoids regulate airway anion transporters through Rho kinase- and cAMP-dependent mechanisms2011

    • Author(s)
      Hibino Y, Morise M, Ito Y, Mizutani T, Matsuno T, Ito S, Hashimoto N, Sato M, Kondo M, Imaizumi K, and Hasegawa Y
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 45(4) Pages: 684-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Mesenchymal Stem Cells Stably Transduced with a Dominant-Negative Inhibitor of CCL2 Greatl Attenuate Bleomycin-Induced Lung Damage2011

    • Author(s)
      Sigeki Saito, Naozumi Hashimoto, 3番目
    • Journal Title

      Am J Pathol

      Volume: 179 Pages: 1088-1094

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Attenuation of transforming growth factor-beta-stimulated collagen production in fibroblasts by quercetin-induced heme oxygenase-12011

    • Author(s)
      Nakamura T, Matsushima M, Hayashi Y, Shibasaki M, Imaizumi K, Hashimoto N, Shimokata K, Hasegawa Y, Kawabe T
    • Journal Title

      Am J Respir Cell Mol Biol.

      Volume: 44(5) Pages: 614-20

    • DOI

      10.1165/rcmb.2010-0338oc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590856, KAKENHI-PROJECT-22590857, KAKENHI-PROJECT-23659431, KAKENHI-PROJECT-23790292
  • [Journal Article] Mesenchymal Stem Cells Stably Transduced with a Dominant-Negative Inhibitor of CCL2 Greatly Attenuate Bleomycin-Induced Lung Damage.2011

    • Author(s)
      Saito S, Nakayama T, Hashimoto N, MiyataY, Egashira K, Nakao N, Nishiwaki S, Hasegawa M, Hasegawa Y, Naoe T
    • Journal Title

      Am J Pathol

      Volume: 179(3) Pages: 1088-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Involvement of the transcription factor twist in phenotype alteration through epithelial-mesenchymal transition in lung cancer cells.2011

    • Author(s)
      Nakashima H, Hashimoto N, Aoyama D, Kohnoh T, Sakamoto K, Kusunose M,Imaizumi K, Takeyama Y, Sato M, Kawabe T, Hasegawa Y
    • Journal Title

      Mol Carcinog.

      Volume: 51(5) Pages: 400-410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Journal Article] Capsaicinoids regulate airway anion transporters through Rho kinaseandc AMP-dependent mechanisms2011

    • Author(s)
      Hibino Y, Morise M, Ito Y, Mizutani T, Matsuno T, Ito S, Hashimoto N, Sato M, Kondo M, Imaizumi K, and Hasegawa Y
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 45(4) Pages: 684-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Attenuation of TGF-ss-Stimulated Collagen Production in Fibroblasts by Quercetin-Induced HO-12011

    • Author(s)
      Toshinobu Nakamura, Naozumi Hashimoto, 6番目
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 44 Pages: 614-620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Capsaicinoids regulate airway anion transporters through Rho kinase- and cyclic AMP-dependent mechanisms.2011

    • Author(s)
      Hibino Y
    • Journal Title

      Am J Respir Cell Mol Biol.

      Volume: 45 Pages: 684-691

    • DOI

      10.1165/rcmb.2010-0332oc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590857, KAKENHI-PROJECT-23659431
  • [Journal Article] Differential Th1/Th2 chemokine expression in interstitial pneumonia2010

    • Author(s)
      Naozumi Hashimoto(4番目)
    • Journal Title

      Am J Med Sci

      Volume: 339 Pages: 41-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Endothelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis.2010

    • Author(s)
      Hashimoto N, Hasegawa Y, et al.
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 43 Pages: 161-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390257
  • [Journal Article] Knockdown of ZEB1, a Master Epithelial-to-Mesenchymal Transition (EMT) Gene, Suppresses Anchorage-independent Cell Growth of Lung Cancer Cells2010

    • Author(s)
      Naozumi Hashimoto(8番目)
    • Journal Title

      Cancer Letters

      Volume: 296 Pages: 216-224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Heterologous regulation of anion transporters by menthol in human airway epithelial cells2010

    • Author(s)
      Naozumi Hashimoto(6番目)
    • Journal Title

      Eur J Pharmacol

      Volume: 635 Pages: 204-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Endothelial-mesenchymal transition in bleomycin-inducedpulmonary fibrosis2010

    • Author(s)
      Hashimoto N, Hasegawa Y, et al.(8人中8番目)
    • Journal Title

      Am J Resp Cell Mol Biol

      Volume: 43 Pages: 161-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390257
  • [Journal Article] Endothelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis2010

    • Author(s)
      Naozumi Hashimoto
    • Journal Title

      Am J Respir Cell Mol Blol

      Volume: 43 Pages: 161-172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Erythromycin-induccd CXCR4 expression on microvascular endothelial cell2009

    • Author(s)
      Naozumi Hashimoto
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol 297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model2009

    • Author(s)
      Naozumi Hashimoto
    • Journal Title

      BMC Pulm Med 9

      Pages: 45-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Journal Article] Up-regulation of Surfactant Protein Production in a Mouse Model of Secondary Pulmonary Alveolar Proteinosis2008

    • Author(s)
      Shibasaki1 M, Hashimoto K, Okamoto M, Hayashi Y, Imaizumi1K, Hashimoto N, Ozaki N, Yokoi T, Takagi K, Hasegawa Y, Shimokata K, Kawabe T
    • Journal Title

      Am J Respir Cell Mol Biol (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590890
  • [Journal Article] TH1/TH2 immune response in lung fibroblasts in interstitial lung disease2008

    • Author(s)
      Sumida A, Hasegawa Y, Okamoto M, Hashimoto N, Imaizumi K, Yatsuya H, Yokoi T, Takagi K, Shimokata K, Kawabe T
    • Journal Title

      Arch Med Res 39

      Pages: 503-510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590890
  • [Journal Article] Healthcare-associated pneumonia among hospitalized patients in a Japanese community hospital2008

    • Author(s)
      Shindo Y, Shinji Sato S, Maruyama E, Ohashi T, Ogawa M, Hashimoto N, Imaizumi K, Sato T, Hasegawa Y
    • Journal Title

      Chest (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590890
  • [Journal Article] Successful re-treatment with gefitinib for carcinomatous meningitis as disease recurrence of non-small-cell lung cancer.2007

    • Author(s)
      橋本 直純
    • Journal Title

      Lung Cancer 53

      Pages: 387-390

    • Data Source
      KAKENHI-PROJECT-17790530
  • [Presentation] The PTEN protein, not lipid, phosphatase activity negatively regulate TGFβ-induced EMT in lung alveolar cells.2015

    • Author(s)
      Hashimoto N, Aoyama D, Hasegawa Y
    • Organizer
      The 2015 American Thoracic Society (ATS) International Conference
    • Place of Presentation
      デンバー、米国
    • Year and Date
      2015-05-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15322
  • [Presentation] Modulation of Phosphorylation Sites In The PTEN C-Terminal Inhibits TGFβ-Induced EMT In Lung Cancers Via Blockade Of Translocation Of β-Catenin Into Cytoplasm”2013

    • Author(s)
      Hashimoto N, Aoyama D, Hasegawa Y
    • Organizer
      The 2013 American Thoracic Society (ATS) International Conference
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Presentation] Translocation of β-catenin into cytoplasm during TGFβ-induced EMT is negatively regulated by phosphorylation of the PTEN C-terminus in lung cancers.2013

    • Author(s)
      Naozumi Hashimoto, Daisuke Aoyama, Yoshinori Hasegawa
    • Organizer
      European Respiratory Society Annual Congress 2013
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Presentation] Compensatory induction of mutated phosphorylation sites in the PTEN C-terminal suppresses tumor growth in lung cancers in vivo.2012

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      The 2012 American Thoracic Society (ATS) International Conference
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] Compensatory induction of mutation of phosphorylation sites in PTEN inhibits hypoxia-induced epithelial-mesenchymal transition (EMT) in epithelial cells2012

    • Author(s)
      Kimura M, Hashimoto N, Kusunose M, Hasegawa Y
    • Organizer
      The FASEB Summer Research Conference
    • Place of Presentation
      Saxtons River, USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] 気管支鏡検査前スクリーニング肺機能検査は慢性閉塞性肺疾患(COPD)早期診断方法として有効性である2012

    • Author(s)
      橋本直純
    • Organizer
      日本呼吸器内視鏡学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Presentation] Various effect of compensatory induction of PTEN wild against TGFβ-induced epithelial-mesenchymal transition (EMT) in epithelial cells2012

    • Author(s)
      Kusunose M, Hashimoto N, Kimura M, Hasegawa Y
    • Organizer
      The FASEB Summer Research Conference
    • Place of Presentation
      Saxtons River, USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] Inhibition of TGFβ-induced phenotype alterations through epithelial-mesenchymal transition (EMT) in epithelial cells by gene mutation of phosphorylation sites in PTEN2012

    • Author(s)
      Hashimoto N, Kusunose M, Kimura M, Hasegawa Y
    • Organizer
      The FASEB Summer Research Conference
    • Place of Presentation
      Saxtons River, USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] Acute and persistent hypoxia differentially induces surfactant protein D modulation and epithelial-mesenchymal transition via hypoxia-inducible factor 1α and twist stimulation in acute lung injury/fibrosis2012

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      The 2012 American Thoracic Society (ATS) International Conference
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Presentation] Compensatory induction of mutated phosphorylation sites in the PTEN C-terminal suppresses tumor growth in lung cancers in vivo2012

    • Author(s)
      Hashimoto N, Aoyama D, Sakamoto K, Hasegawa Y
    • Organizer
      The 2012 American Thoracic Society (ATS) International Conference
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] Compensatory induction of mutated phosphorylation sites in the PTEN C-terminal suppresses tumor growth in lung cancers in vivo2012

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      The 2012 American Thoracic Society (ATS) International Conference
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Presentation] Inhibition of TGFβ-induced phenotype alterations through epithelial-mesenchymal transition (EMT) in epithelial cells by gene mutation of phosphorylation sites in PTEN.2012

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      The FASEB Summer Research Conference,
    • Place of Presentation
      Saxtons River, USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] Spirometric inspiratory capacity is a useful preoperative assessment in patients undergoing thoracic surgery2012

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      The 2012 American Thoracic Society (ATS) International Conference
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-24591162
  • [Presentation] Acute and persistent hypoxia differentially induces surfactant protein D modulation and epithelial-mesenchymal transition via hypoxia-inducible factor 1α and twist stimulation in acute lung injury/fibrosis.2012

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      The 2012 American Thoracic Society (ATS) International Conference
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] Acute and persistent hypoxia differentially induces surfactant protein D modulation and epithelial-mesenchymal transition via hypoxia-inducible factor 1αand twist stimulation in acute lung injury/fibrosis2012

    • Author(s)
      Hashimoto N, Sakamoto K, Hasegawa Y
    • Organizer
      The 2012 American Thoracic Society (ATS) International Conference
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] A critical involvement of chronic obstructive pulmonary disease as a preo perative risk factor in the patients with lung cancer undergoing surgical resection2011

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      American Thoracic Society 2011
    • Place of Presentation
      アメリカ、デンバー
    • Year and Date
      2011-05-17
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] Inhibition of TGFbeta induced epithelial mesenchymal transition in lung cancer by modulation of PTEN c-terminal tail2011

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      日本癌学会総会
    • Place of Presentation
      日本、名古屋
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] Modulated Expression Of Surfactant Protein D In Acute Lung Injury Might Be Associated With Epithelial-Mesenchymal Transition In Epithelial Cells.2011

    • Author(s)
      Sakamoto K, Hashimoto N, Imaizumi K, Taniguchi H, Kondoh Y, Kohnoh T, Aoyama D, Ogawa T,Hasegaya Y.
    • Organizer
      American Thoracic Society International Conference 2011 (ATS・2011)
    • Place of Presentation
      Denver,Colorado,USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] Inhibition of Hypoxia-induced phenotype alterations through epithelial-mesenchymal transition(EMT) in lung cancer by gene modulation of phosphorylation sites in tumor suppressor PTEN European Respiratory Society Congress2011

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      オランダ、アムステルダム
    • Place of Presentation
      アムステルダム
    • Year and Date
      2011-09-27
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] A critical involvement of chronic obstructive pulmonary disease as a preoperative risk factor in the patients with lung cancer undergoing surgical resection2011

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      American Thoracic Society 2011 International conference
    • Place of Presentation
      アメリカ、デンバー
    • Year and Date
      2011-05-17
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] Inhibition of TGFbeta induced epithelial mesenchymal transition in lung cancer by modulation of PTEN c-terminal tail2011

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      日本癌学会総会
    • Place of Presentation
      日本,名古屋
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] Inhibition of Hypoxia-induced phenotype alterations through epithelial-mesenchymal transition (EMT) in lung cancer by gene modulation of phosphorylation sites in tumor suppressor PTEN2011

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      European Respiratory Society Congress
    • Place of Presentation
      オランダ、アムステルダム
    • Year and Date
      2011-09-26
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] Inspiratory capacity is a new preoperative risk predictor in the patients with lung cancer undergoing surgical resection2011

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      European Respiratory Society Congress
    • Place of Presentation
      オランダ、アムステルダム
    • Year and Date
      2011-09-27
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] Inhibition Of TGF-Beta-Induced Phenotype Alterations Through Epithelial-Mesenchymal Transition(EMT) In Lung Cancer By Gene Modulation Of Phosphorylations Sites In Tumor Suppressor Pten2011

    • Author(s)
      Aoyama D, Hashimoto N, Imaizumi K, Kohnoh T, Sakamoto K, Ogawa T, Hasegaya Y.
    • Organizer
      American Thoracic Society International Conference 2011 (ATS・2011)
    • Place of Presentation
      Denver,Colorado,USA
    • Data Source
      KAKENHI-PROJECT-23659431
  • [Presentation] Inspiratory capacity is a new preoperative risk predictor in the patients with lung cancer undergoing surgical resection European Respiratory Society Congress2011

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      オランダ、アムステルダム
    • Place of Presentation
      アムステルダム
    • Year and Date
      2011-09-27
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] A critical Involvement or chronic obstructive pulmonary disease as a preoperative risk factor in the patients with lung cancer undergoing surgical resection2011

    • Author(s)
      N.Hashimoto
    • Organizer
      ATS International Conference
    • Place of Presentation
      Denver, Colorado USA
    • Year and Date
      2011-05-15
    • Data Source
      KAKENHI-PROJECT-22590857
  • [Presentation] Involvement of fibrosis-related growth factors in endothelial-mesenchymal transition2010

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      2010 EB
    • Place of Presentation
      Vermont USA
    • Year and Date
      2010-08-10
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] Involvement of fibrosis-related growth factors in endothelial-mesenchymal transition2010

    • Author(s)
      Naozumi Hashimoto
    • Organizer
      ATS 2010 International Conference
    • Place of Presentation
      New Orleans USA
    • Year and Date
      2010-05-17
    • Data Source
      KAKENHI-PROJECT-21590987
  • [Presentation] Induction of CXCR4 surface expression on microvascular endothelial cells by fourteen membered ring macrolldes.2008

    • Author(s)
      Hashimoto N, et al.
    • Organizer
      2008 International Conference of American Thoracic Society
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2008-05-21
    • Data Source
      KAKENHI-PROJECT-19659211
  • [Presentation] Comprehensive analysis of the PTEN domains on TGFβ-induced aberrant cell motility in lung alveolar/epithelial cells by using PTEN constructs with deletion mutants

    • Author(s)
      Hashimoto N, Kusunose M, Aoyama D, Kimura M, Hasegawa Y
    • Organizer
      European Respiratory Society Annual Congress 2014
    • Place of Presentation
      Munchen, Germany
    • Year and Date
      2014-09-06 – 2014-09-10
    • Data Source
      KAKENHI-PROJECT-24591162
  • 1.  HASEGAWA Yoshinori (20270986)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 40 results
  • 2.  若原 恵子 (00631433)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  阪本 考司 (00635633)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  IMAIZUMI Kazuyoshi (50362257)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 5.  KONDO Masashi (00378077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SATO Mitsuo (70467281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 7.  中村 彰太 (20612849)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  古川 大記 (30837654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  芳川 豊史 (00452334)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  猪股 弥生 (90469792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Miyazaki Shinichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  NAKAYAMA Takayuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  TATSUHIRO Sato
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  KAWABE Tsutomu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 15.  MATSUSHIMA Miyoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  直江 知樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  森瀬 昌宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  進藤 有一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  田中 一大
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  関戸 好孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  中瀬 生彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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