SATO Mitsuo 佐藤光夫

Researcher Number	70467281
Other IDs	https://orcid.org/0000-0001-5458-9576
Affiliation (Current)	2025: 名古屋大学, 医学系研究科(保健), 教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 名古屋大学, 医学系研究科(保健), 教授 2017: 名古屋大学, 医学部附属病院, 准教授 2012 – 2016: 名古屋大学, 医学部附属病院, 講師 2012: 名古屋大学, 医学系研究科, 講師 2011 – 2012: 名古屋大学, 大学院・医学系研究科, 講師 … More 2011: 名古屋大学, 医学(系)研究科(研究院), 講師 2011: 名古屋大学, 医学系研究科, 助教 2010: 名古屋大学, 医学系研究科, COE特任助教 2010: National Institute for Longevity Sciences,NCGG, 大学院・医学系研究科, 特任助教 2010: 国立長寿医療センター病院, 医長 2009 – 2010: Nagoya University, 大学院・医学系研究科, COE特任助教 2008: 名古屋大学, 国立長寿医療センター病院呼吸器科, 医長 2008: National Institute for Longevity Sciences,NCGG, 老化機構研究部, 研究員 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Medium-sized Section 53:Organ-based internal medicine and related fields Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine / Applied pharmacology
Keywords	Principal Investigator 肺癌 / 変異KRAS / 創薬 / 上皮間葉細胞転換 / 細胞老化 / プールshRNA / p53 / アポトーシス / 肺がん / 長鎖非翻訳RNA … More / ドライバーがん遺伝子 / ドライバー遺伝子 / ドライバー癌遺伝子 / 創薬研究 / クラスター形成 / EGFR 遺伝子変異 / RNA干渉 / EGFR遺伝子変異 / 不死化正常ヒト気管支上皮細胞 / 国際研究者交流 / 正常ヒト気管支上皮細胞発癌モデル（HBEC） / プロテアソーム / プールshRNAライブラリー / アノイキス / EGFR / KRAS / ｐ53 / 不死化正常気管支細胞 / 国際情報交換 / 細胞周期 / EMT / マイクロRNA / 非閉塞性肺疾患癌 / 非閉塞性肺疾患 / 上皮間葉系細胞転換 … More Except Principal Investigator 肺癌 / 肺がん / PDXマウス / 細胞増殖 / 新規治療標的 / メカノバイオロジー / カルシウムイオン / メカニカルストレス / ピリミジン代謝 / LKB1不活化肺癌 / 新規治療戦略 / 細胞周期停止 / 腫瘍増殖因子 / 新規個別化治療 / ドラッグリポジショニング / 予後因子 / 細胞周期制御因子 / オキシトシン受容体阻害剤 / オキシトシン / オキシトシン受容体 / 悪性中皮腫 / バイオマーカー / メカノセンサー / 肺線維症 / 喘息 / ストレッチ / Piezo1 / 基質硬度 / トリプトファン / 循環腫瘍細胞 / マイクロリボ核酸 / リンパ節転移 / 呼吸器内科 / 内科 / VEGF / HIF1α / EMT / リンパ節 / 呼吸器病学 / STIM-1 / ARDS / 肺微小血管内皮 / メカノトランスダクション / カルシウムチャネル / TRPチャネル / 呼吸生理学 / cAMP / 気道平滑筋細胞 / 血管内皮 / COPD / 気管支喘息 / 気道平滑筋 / Orai1 / STIM1 / TRP / 遺伝子多型 / 医薬品副作用 / QT延長 / がん化学療法 Less

MAPKシグナル伝達経路を負に制御するフォスファターゼ遺伝子を標的とする肺癌治療Principal Investigator
- Principal Investigator
  
  佐藤光夫
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
ピリミジン塩基合成経路を標的としたLKB1不活化肺癌に対する新規治療法の開発
- Principal Investigator
  
  田中一大
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
長鎖非翻訳RNAを標的とする変異KRAS肺癌の合成致死治療の開発Principal Investigator
- Principal Investigator
  
  佐藤光夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Nagoya University
ドライバー癌遺伝子誘導性の細胞老化を作用機序とする変異KRAS肺癌の創薬研究Principal Investigator
- Principal Investigator
  
  佐藤光夫
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
肺癌免疫チェックポイント阻害薬併用療法のバイオマーカー研究
- Principal Investigator
  
  長谷哲成
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
機械感受性チャネルPiezo1とメカノセンサーを標的とした呼吸器疾患の病態解明
- Principal Investigator
  
  伊藤理
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Aichi Medical University
Oxytocin receptor is a promising therapeutic target of malignant mesothelioma
- Principal Investigator
  
  TANAKA ICHIDAI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
analysis of lung cancer immunotherapy targeting tryptophan metabolism
- Principal Investigator
  
  Kondo Masashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Fujita Health University
Development of therapeutics for lung cancer that target factors stabilizing epithelial-to-mesenchymal transitionPrincipal Investigator
- Principal Investigator
  
  Sato Mitsuo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Nagoya University
Development of novel therapeutics that utilize driver oncogene-induced senescencePrincipal Investigator
- Principal Investigator
  
  Sato Mitsuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nagoya University
Analysis of resistance against molecular targeted therapy with circulating tumor cells with stemness properties
- Principal Investigator
  
  Hase Tetsunari
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya University
Analysis of mechanical stress in lung cancer cells for therapeutic target search
- Principal Investigator
  
  Kondo Masashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Fujita Health University
  Nagoya University
Identification of driver genes in lung cancer through a semi-genome wide shRNA library screen based on anoikis resistance phenotypePrincipal Investigator
- Principal Investigator
  
  Sato Mitsuo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya University
Development of a novel therapeutic strategy targeting genes contributing to forming cluster in EGFR mutated lung cancerPrincipal Investigator
- Principal Investigator
  
  Sato Mitsuo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya University
Analysis of microRNA for the diagnosis and treatment of lung cancer
- Principal Investigator
  
  KONDO Masashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya University
Exploratory study for identifying EMT-associated genes as novel therapeutics for lung cancerPrincipal Investigator
- Principal Investigator
  
  MITSUO Sato
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya University
Therapeutic approach for respiratory diseases targeting TRP genes
- Principal Investigator
  
  ITO Satoru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya University
Exploration of new therapy and diagnosis in lymph metastasis of lung cancer based on theprofile of lymphangiogenic-related genes expression
- Principal Investigator
  
  IMAIZUMI Kazuyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Fujita Health University
  Nagoya University
Clinical and genetic factors of drug-induced QT interval prolongation in patients who receive cancer chemotherapy
- Principal Investigator
  
  ANDO Yuichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagoya University
Identification of Epithelial-to-Mesenchymal Transition-Associated Genes as Therapeutic Targets for Lung CancerPrincipal Investigator
- Principal Investigator
  
  SATO Mitsuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  National Institute for Longevity Sciences,NCGG

[Book] MicroRNA in Regenerative Medicine2023
- Author(s)
  CHAPTER 24 miRNAs in Transitions: EMT, MET, and EndoMT. 659 Mitsuo Sato, David S. Shames, and Yoshinori Hasegawa
- Total Pages
  1132
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-22K19522
[Book] MicroRNA in Regenerative Medicine2015
- Author(s)
  Mitsuo Sato, David S. Shames, Yoshinori Hasegawa
- Total Pages
  1259
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-26670416
[Book] Chapter 34: miRNAs in Transitions: EMT, MET, and EndoMT2014
- Author(s)
  Mitsuo Sato, David S. Shames, Yoshinori Hasegawa
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-23591145
[Book] Micro RNA in Regenerative Medicine2014
- Author(s)
  Mitsuo Sato, David S. Shames, Yoshinori Hasegawa
- Publisher
  Elsevier (in press)
- Data Source
  KAKENHI-PROJECT-23591145
[Book] 抗悪性腫瘍薬コンサルトブック2010
- Author(s)
  南博信編、佐藤光夫分担執筆
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] Contrast-enhanced ultrasound imaging for monitoring the efficacy of near-infrared photoimmunotherapy2023
- Author(s)
  Matsuoka Kohei、Yamada Mizuki、Fukatsu Noriaki、Goto Kyoichi、Shimizu Misae、Kato Ayako、Kato Yoshimi、Yukawa Hiroshi、Baba Yoshinobu、Sato Mitsuo、Sato Kazuhide
- Journal Title
  
  eBioMedicine
  
  Volume: 95 Pages: 104737-104737
- DOI
  10.1016/j.ebiom.2023.104737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19522
[Journal Article] Silencing of GRHL2 induces epithelial to mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth2023
- Author(s)
  Kawabe Nozomi、Matsuoka Kohei、Komeda Kazuki、Muraki Nao、Takaba Miho、Togami Yasuha、Ito Yumeno、Yamada Mizuki、Sunaga Noriaki、Girard Luc、Minna John、Cai Ling、Xie Yang、Tanaka Ichidai、Morise Masahiro、Sato Mitsuo
- Journal Title
  
  Oncology Letters
  
  Volume: 26 Issue: 3
- DOI
  10.3892/ol.2023.13977
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19522
[Journal Article] The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β‐catenin signaling in lung cancer2023
- Author(s)
  Sunaga Noriaki、Kaira Kyoichi、Shimizu Kimihiro、Tanaka Ichidai、Miura Yosuke、Nakazawa Seshiru、Ohtaki Yoichi、Kawabata‐Iwakawa Reika、Sato Mitsuo、Girard Luc、Minna John D.、Hisada Takeshi
- Journal Title
  
  Thoracic Cancer
  
  Volume: 15 Issue: 2 Pages: 131-141
- DOI
  10.1111/1759-7714.15169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19522
[Journal Article] Decrease in cholesterol in the cell membrane is essential for Nrf2 activation by quercetin2023
- Author(s)
  Matsushima Miyoko、Nose Haruka、Tsuzuki Hikaru、Takekoshi Masahiro、Kusatsugu Yuto、Taniguchi Hinata、Ohdachi Tomoko、Hashimoto Naozumi、Sato Mitsuo、Kawabe Tsutomu
- Journal Title
  
  The Journal of Nutritional Biochemistry
  
  Volume: 116 Pages: 109329-109329
- DOI
  10.1016/j.jnutbio.2023.109329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07824, KAKENHI-PROJECT-20K11529, KAKENHI-PROJECT-22K19522, KAKENHI-PROJECT-23K26686
[Journal Article] High-performance glass filters for capturing and culturing circulating tumor cells and cancer-associated fibroblasts2023
- Author(s)
  Tanaka Hiromasa、Iwata Daijiro、Shibata Yuki、Hase Tetsunari、Onoshima Daisuke、Yogo Naoyuki、Shibata Hirofumi、Sato Mitsuo、Ishikawa Kenji、Nagasawa Ikuo、Hasegawa Yoshinori、Ishii Makoto、Baba Yoshinobu、Hori Masaru
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 4130-4130
- DOI
  10.1038/s41598-023-31265-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18616, KAKENHI-PROJECT-19H05462, KAKENHI-PROJECT-21H04451, KAKENHI-PROJECT-21H01072, KAKENHI-PROJECT-21H02924
[Journal Article] Resistance to mutant KRAS V12-induced senescence in an hTERT/Cdk4-immortalized normal human bronchial epithelial cell line2022
- Author(s)
  Muraki N, Yamada M, Doki H, Nakai R, Komeda K, Goto D, Kawabe N, Matsuoka K, Matsushima M, Kawabe T, Tanaka I, Morise M, Shay JW, Minna JD, Sato M.
- Journal Title
  
  Exp Cell Res .
  
  Volume: 414 Issue: 1 Pages: 113053-113053
- DOI
  10.1016/j.yexcr.2022.113053
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22617, KAKENHI-PROJECT-21H02924, KAKENHI-PROJECT-20K07824, KAKENHI-PROJECT-20K11529, KAKENHI-PROJECT-19K07910, KAKENHI-PROJECT-22K19522
[Journal Article] Leukocyte depletion and size-based enrichment of circulating tumor cells using a pressure-sensing microfiltration device.2022
- Author(s)
  Onoshima D, *Hase T, Kihara N, Kuboyama D, Tanaka H, Ozawa N, Yukawa H, Sato M, Ishikawa K, Hasegawa Y, Ishii M, Hori M, Baba Y.
- Journal Title
  
  ACS Measurement Science Au
  
  Volume: 3 Issue: 2 Pages: 113-119
- DOI
  10.1021/acsmeasuresciau.2c00057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05589, KAKENHI-PROJECT-21H04451, KAKENHI-PROJECT-21H02924
[Journal Article] Oxytocin receptor is a promising therapeutic target of malignant mesothelioma2021
- Author(s)
  Oxytocin receptor is a promising therapeutic target of malignant mesothelioma. Kodama Y, Tanaka I, Sato T, Hori K, Gen S, Morise M, Matsubara D, Sato M, Sekido Y, Hashimoto N.
- Journal Title
  
  Cancer science
  
  Volume: 112 Issue: 9 Pages: 3520-3532
- DOI
  10.1111/cas.15025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22617, KAKENHI-PROJECT-19H03527, KAKENHI-PROJECT-20K21599, KAKENHI-PROJECT-20H03689
[Journal Article] Spatiotemporal depletion of tumor-associated immune checkpoint PD-L1 with near-infrared photoimmunotherapy promotes antitumor immunity2021
- Author(s)
  Shunichi Taki, Kohei Matsuoka, Yuko Nishinaga, Kazuomi Takahashi, Hirotoshi Yasui, Chiaki Koike, Misae Shimizu , Mitsuo Sato , Kazuhide Sato
- Journal Title
  
  J Immunother Cancer .
  
  Volume: 9 Issue: 11 Pages: e003036-e003036
- DOI
  10.1136/jitc-2021-003036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22617, KAKENHI-PROJECT-21K07217
[Journal Article] Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity2021
- Author(s)
  Morita Nanaka、Hoshi Masato、Hara Takeshi、Ninomiya Soranobu、Enoki Taisuke、Yoneda Misao、Tsurumi Hisashi、Saito Kuniaki
- Journal Title
  
  Oncology Letters
  
  Volume: 22 Issue: 5 Pages: 110-110
- DOI
  10.3892/ol.2021.13051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08667, KAKENHI-PROJECT-20K07432
[Journal Article] Immortalized normal human lung epithelial cell models for studying lung cancer biology2020
- Author(s)
  Sato M, Shay JW, Minna JD.
- Journal Title
  
  Respir Investig .
  
  Volume: 58(5) Pages: 344-354
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22617
[Journal Article] Phenotypic screening using large-scale genomic libraries to identify drug targets for the treatment of cancer2020
- Author(s)
  Mitsuo Sato
- Journal Title
  
  Oncol Lett
  
  Volume: 19 Pages: 3617-3626
- DOI
  10.3892/ol.2020.11512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02819
[Journal Article] Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2020
- Author(s)
  Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, Yamamoto Y, Tezuka H, Tomita H, Hara A, Saito K.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 26 Issue: 9 Pages: 918-932
- DOI
  10.3748/wjg.v26.i9.918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-19K08667, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873
[Journal Article] Immortalized normal human lung epithelial cell models for studying lung cancer biology2020
- Author(s)
  Sato M, Shay JW, Minna JD.
- Journal Title
  
  Respir Investig
  
  Volume: 58 Issue: 5 Pages: 344-354
- DOI
  10.1016/j.resinv.2020.04.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02819
[Journal Article] UHRF1, a Regulator of Methylation, as a Diagnostic and Prognostic Marker for Lung Cancer2020
- Author(s)
  Goto Daiki、Komeda Kazuki、Uwatoko Natsuki、Nakashima Moeka、Koike Mayu、Kawai Kaho、Kodama Yuta、Miyazawa Ayako、Tanaka Ichidai、Hase Tetsunari、Morise Masahiro、Hasegawa Yoshinori、Kawabe Tsutomu、Sato Mitsuo
- Journal Title
  
  Cancer Investigation
  
  Volume: 38 Issue: 4 Pages: 240-249
- DOI
  10.1080/07357907.2020.1747483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07910, KAKENHI-PROJECT-18H02819
[Journal Article] Chemotherapy Induced Changes to Fibrin Clots Properties in Lung Cancer: Is It Favorable?2019
- Author(s)
  Sato M.
- Journal Title
  
  J Thorac Dis
  
  Volume: 11(Suppl 9) Issue: S9 Pages: S1126-S1128
- DOI
  10.21037/jtd.2019.04.103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22617
[Journal Article] Chemotherapy Induced Changes to Fibrin Clots Properties in Lung Cancer: Is It Favorable?2019
- Author(s)
  Mitsuo Sato
- Journal Title
  
  J Thorac Dis .
  
  Volume: 11(Suppl 9)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02819
[Journal Article] eIF2β, a Subunit of Translation-Initiation Factor EIF2, Is a Potential Therapeutic Target for Non-Small Cell Lung Cancer2018
- Author(s)
  Tanaka Ichidai、Sato Mitsuo、Kato Toshio、Goto Daiki、Kakumu Tomohiko、Miyazawa Ayako、Yogo Naoyuki、Hase Tetsunari、Morise Masahiro、Sekido Yoshitaka、Girard Luc、Minna John D.、Byers Lauren A.、Heymach John V.、Coombes Kevin R.、Kondo Masashi、Hasegawa Yoshinori
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 1843-1852
- DOI
  10.1111/cas.13602
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09216
[Journal Article] Regulation of PD-L1 expression by matrix stiffness in lung cancer cells2018
- Author(s)
  Miyazawa Ayako、Ito Satoru、Asano Shuichi、Tanaka Ichidai、Sato Mitsuo、Kondo Masashi、Hasegawa Yoshinori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 3 Pages: 2344-2349
- DOI
  10.1016/j.bbrc.2017.12.115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09216, KAKENHI-PROJECT-16K09578
[Journal Article] Specific copy number changes as potential predictive markers for adjuvant chemotherapy in non-small cell lung cancer2018
- Author(s)
  Mitsuo Sato
- Journal Title
  
  Transl Lung Cancer Res.
  
  Volume: 7(Suppl 4) Issue: S4 Pages: S346-S348
- DOI
  10.21037/tlcr.2018.11.04
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02819
[Journal Article] Identification of Proteasomal Catalytic Subunit PSMA6 as a Therapeutic Target for Lung Cancer.2017
- Author(s)
  Kakumu T, Sato M, Goto D, Kato T, Yogo N, Hase T, Morise M, Fukui T, Yokoi K, Sekido Y, Girard L, Minna JD, Byers LA, Heymach JV, Coombes KR, Kondo M, Hasegawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 4 Pages: 732-743
- DOI
  10.1111/cas.13185
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293197, KAKENHI-PROJECT-15K09216
[Journal Article] ZEB1 drives epithelial-to-mesenchymal transition in lung cancer.2016
- Author(s)
  Larsen JE, Nathan V, Osborne JK, Farrow RK, Deb D, Sullivan JP, Dospoy PD, Augustyn A, Hight SK, Sato M, Girard L, Behrens C, Wistuba II, Gazdar AF, Hayward NK, Minna JD.
- Journal Title
  
  J Clin Invest.
  
  Volume: 126 Issue: 9 Pages: 3219-35
- DOI
  10.1172/jci76725
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293197
[Journal Article] Nuclear Receptor Expression and Function in Human Lung Cancer Pathogenesis.2015
- Author(s)
  Kim J, Sato M, Choi JW, Kim HW, Yeh BI, Larsen JE, Minna JD, Cha JH, Jeong Y.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 8 Pages: e0134842-e0134842
- DOI
  10.1371/journal.pone.0134842
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670416, KAKENHI-PROJECT-26293197
[Journal Article] Growth inhibitory effects of miR-221 and miR-222 in non-small cell lung cancer cells.2015
- Author(s)
  Yamashita R, Sato M, Kakumu T, Hase, T, Yogo, N, Maruyama E, Sekido Y, Kondo M, Hasegawa, Y.
- Journal Title
  
  Cancer Medicine
  
  Volume: 4 Issue: 4 Pages: 551-564
- DOI
  10.1002/cam4.412
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09216, KAKENHI-PROJECT-26670416, KAKENHI-PROJECT-26293197
[Journal Article] Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.2013
- Author(s)
  Sato M, Larsen JE, Lee W, Sun H, Shames DS, Dalvi MP, Ramirez RD, Tang H, Dimaio JM, Gao B, Xie Y, Wistuba II, Gazdar AF, Shay JW, Minna JD
- Journal Title
  
  Mol Cancer Res
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591145
[Journal Article] TIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival2013
- Author(s)
  Yoshida K, Sato M, Hase T, Elshazley M, Yamashita R, Usami N, Taniguchi T, Yokoi K, Nakamura S, Kondo M, Girard L, Minna JD, Hasegawa Y
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 171-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591144
[Journal Article] NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.2013
- Author(s)
  Osborne JK, Larsen JE, Shields MD, Gonzales JX, Shames DS, Sato M, Kulkarni A, Wistuba II, Girard L, Minna JD, Cobb MH
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 110 Issue: 16 Pages: 6524-9
- DOI
  10.1073/pnas.1303932110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591145
[Journal Article] Endobronchial ultrasound transbronchial needle aspiration in older people2013
- Author(s)
  Okachi S, Imai N, Imaizumi K, Hase T,Shindo Y, Sakamoto K, Aso H, Wakahara K,Hashimoto I, Ito S, Hashimoto N, Sato M,Kondo M, Hasegawa Y.
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 13 Issue: 4 Pages: 986-992
- DOI
  10.1111/ggi.12043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590857
[Journal Article] TIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival.2013
- Author(s)
  Yoshida K, Sato M, Hase T, Kondo M
- Journal Title
  
  Cancer Sci.
  
  Volume: 104(2) Pages: 171-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591144
[Journal Article] An aqueous fraction of Sauropus androgynus might be responsible for bronchiolitis obliterans.2013
- Author(s)
  Hashimoto I, Imaizumi K, Hashimoto N,Furukawa H, Noda Y, Kawabe T, Honda T,Ogawa T, Matsuo M, Imai N, Ito S, Sato M,Kondo M, Shimokata K, Hasegawa Y.
- Journal Title
  
  Respirology
  
  Volume: 18(2) Pages: 340-347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590857
[Journal Article] IMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival.2013
- Author(s)
  Yoshida K, Sato M, Hase T, Elshazley M, Yamashita R, Usami N, Taniguchi T, Yokoi K, Nakamura S, Kondo M, Girard L, Minna JD, Hasegawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 2 Pages: 171-7
- DOI
  10.1111/cas.12068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591144, KAKENHI-PROJECT-23591145
[Journal Article] Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.2013
- Author(s)
  Sato M, Larsen JE, Lee W, Sun H, Shames DS, Dalvi MP, Ramirez RD, Tang H, DiMaio JM, Gao B, Xie Y, Wistuba II, Gazdar AF, Shay JW, Minna JD
- Journal Title
  
  Mol Cancer Res
  
  Volume: 11 Issue: 6 Pages: 638-650
- DOI
  10.1158/1541-7786.mcr-12-0634-t
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591145
[Journal Article] NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibition.2013
- Author(s)
  Osborne JK, Larsen JE, Gonzales JX, Shames DS, Sato M, Wistuba II, Girard L, Minna JD, Cobb MH.
- Journal Title
  
  Oncogenesis.
  
  Volume: 2 Issue: 8 Pages: e63-e63
- DOI
  10.1038/oncsis.2013.24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591145
[Journal Article] Transient but Not Stable ZEB1 Knockdown Dramatically Inhibits Growth of Malignant Pleural Mesothelioma Cells2012
- Author(s)
  Horio M, Sato M, Takeyama Y, Elshazley M, Yamashita R, Hase T, Yoshida K, Usami N, Yokoi K, Sekido Y, Kondo M, Toyokuni S, Gazdar AF, Minna JD, Hasegawa Y
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19 Pages: 634-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591144
[Journal Article] Transient but Not Stable ZEB1 Knockdown Dramatically Inhibits Growth of Malignant Pleural Mesothelioma Cells.2012
- Author(s)
  Horio M, Sato M, Takeyama Y, Elshazley M, Yamashita R, Hase T, Yoshida K, Usami N, Yokoi K, Sekido Y, Kondo M, Toyokuni S, Gazdar AF, Minna JD, Hasegawa Y.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591145
[Journal Article] Non-Genomic Effects of Fluticasone Propionate and Budesonide on Human Airway Anion Secretion2012
- Author(s)
  Mizutani T, Morise M, Ito Y, Hibino Y,Matsuno T, Ito S, Hashimoto N, Sato M, Kondo M, Imaizumi K, Hasegawa Y
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 47(5) Pages: 645-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590857
[Journal Article] Oncogenic KRAS-induced epiregulin overexpression contributes to aggressive phenotype and is a promising therapeutic target in non-small-cell lung cancer.2012
- Author(s)
  Sunaga N, Kaira K, Imai H, Shimizu K, Nakano T, Shames DS, Girard L, Soh J, Sato M, Iwasaki Y, Ishizuka T, Gazdar AF, Minna JD, Mori M.
- Journal Title
  
  Oncogene
  
  Volume: 印刷中 Issue: 34 Pages: 4034-4042
- DOI
  10.1038/onc.2012.402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591134, KAKENHI-PROJECT-23591145
[Journal Article] STIM1 regulates platelet-derived growth factor-induced migration and Ca2+ influx in human airway smooth muscle cells.2012
- Author(s)
  Suganuma N, Ito S, Aso H, Kondo M, Sato M, Sokabe M, Hasegawa Y.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590837
[Journal Article] STIM1 regulates platelet-derived growth factor-induced migration and Ca^2+ influx in human airway smooth muscle cells2012
- Author(s)
  Suganuma N, Ito S, Aso H, Kondo M, Sato M, Sokabe M, Hasegawa Y
- Journal Title
  
  PLoS One
  
  Volume: 7:
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590837
[Journal Article] Transient but not stable ZEB1 knockdown dramatically inhibits growth of malignant pleural mesothelioma cells.2012
- Author(s)
  Horio M, Sato M, Takeyama Y, Elshazley M, Yamashita R, Hase T, Yoshida K, Usami N, Yokoi K, Sekido Y, Kondo M, Toyokuni S, Gazdar AF, Minna JD, Hasegawa Y
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19 Supple3 Issue: S3 Pages: 634-645
- DOI
  10.1245/s10434-011-2142-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300338, KAKENHI-PROJECT-23591145
[Journal Article] The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma2012
- Author(s)
  Elshazley M, Sato M, Hase T, Yamashita R, Yoshida K, Toyokuni S, Ishiguro F, Osada H, Sekido Y, Yokoi K, Usami N, Shames DS, Kondo M, Gazdar AF, Minna JD, Hasegawa Y
- Journal Title
  
  Int J Cancer
  
  Volume: 131 Pages: 2820-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591144
[Journal Article] The circadian clock gene BMAL1 is a novel therapeutic target for malignant mesothelioma.2012
- Author(s)
  Elshazley M, Sato M, Hase T, Yamashita R, Yoshida K, Toyokuni S, Ishiguro F, Osada H, Sekido Y, Yokoi K, Usami N, Shames DS, Kondo M, Gazdar AF, Minna JD, Hasegawa Y
- Journal Title
  
  Int J Cancer
  
  Volume: 131 Issue: 12 Pages: 2820-31
- DOI
  10.1002/ijc.27598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300338, KAKENHI-PROJECT-23501281, KAKENHI-PROJECT-23591145
[Journal Article] Emerging evidence of Epithelial-to-Mesenchymal Transition in lung carcinogenesis.2012
- Author(s)
  Sato M, Shames DS, Hasegawa Y.
- Journal Title
  
  Respirology.
  
  Volume: 印刷中 Issue: 7 Pages: 1048-1059
- DOI
  10.1111/j.1440-1843.2012.02173.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591145, KAKENHI-PROJECT-23659431
[Journal Article] Knockdown of Oncogenic KRAS in Non-Small Cell Lung Cancers Suppresses Tumor Growth and Sensitizes Tumor Cells to Targeted Therapy.2011
- Author(s)
  Sunaga N, Sato M, et al.
- Journal Title
  
  Mol Cancer Ther 10
  
  Pages: 336-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] Pivotal role of epithelial cell adhesion molecule in the survival of lung cancer cells2011
- Author(s)
  Hase T, et al
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 8 Pages: 1493-1500
- DOI
  10.1111/j.1349-7006.2011.01973.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390257, KAKENHI-PROJECT-23591144, KAKENHI-PROJECT-23591145
[Journal Article] Capsaicinoids regulate airway anion transporters through Rho kinase- and cAMP-dependent mechanisms2011
- Author(s)
  Hibino Y, Morise M, Ito Y, Mizutani T, Matsuno T, Ito S, Hashimoto N, Sato M, Kondo M, Imaizumi K, and Hasegawa Y
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 45(4) Pages: 684-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590857
[Journal Article] Involvement of the transcription factor twist in phenotype alteration through epithelial-mesenchymal transition in lung cancer cells.2011
- Author(s)
  Nakashima H, Hashimoto N, Aoyama D, Kohnoh T, Sakamoto K, Kusunose M,Imaizumi K, Takeyama Y, Sato M, Kawabe T, Hasegawa Y
- Journal Title
  
  Mol Carcinog.
  
  Volume: 51(5) Pages: 400-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590857
[Journal Article] Knockdown of Oncogenic KRAS in Non-Small Cell Lung Cancers SuppressesTumor Growth and Sensitizes Tumor Cells to Targeted Therapy.2011
- Author(s)
  N Sunaga, Sato, ら
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 10 Pages: 336-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] ciations between oxaliplatin-induced peripheral neuropathy and polymorphisms of the ERCC1 and GSTP1 aenes.2010
- Author(s)
  M Inada, M Sato, ら
- Journal Title
  
  Int J Clin Pharmacol Ther
  
  Volume: 48 Pages: 729-734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] Knockdown of ZEB1, a master epithelial-to-mesenchymal transition(EMT)gene, suppresses anchorage-independent cell growth of lung cancer cells.2010
- Author(s)
  Y.Takeyama, M Sato, ら
- Journal Title
  
  Cancer Letters
  
  Volume: 296 Pages: 216-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] Associations between oxaliplatin-induced peripheral neuropathy and polymorphisms of the ERCC1 and GSTP1 genes.2010
- Author(s)
  Megumi Inada, Mitsuo Sato, Ayako Mitsuma, Masataka Sawaki, Yuichi Ando, et al.
- Journal Title
  
  Int J Clin Pharmacol Ther 48
  
  Pages: 729-734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590537
[Journal Article] Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage-independent cell growth of lung cancer cells.2010
- Author(s)
  Takeyama Y, Sato M, Horio M, et al.
- Journal Title
  
  Cancer Lett 296
  
  Pages: 216-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] Associations between oxaliplatin-induced peripheral neuropathy and polymorphisms of the ERCC1 and GSTP1 genes.2010
- Author(s)
  Inada M, Sato M, Morita S, et al.
- Journal Title
  
  Int J Clin Pharmacol Ther 48
  
  Pages: 729-734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] 副作用とその対策 ; 肝・腎・心毒性2009
- Author(s)
  佐藤光夫、安藤雄一
- Journal Title
  
  日本臨牀 67巻増刊
  
  Pages: 505-512
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer.2008
- Author(s)
  Iwanaga K, Sato M, et al.
- Journal Title
  
  Cancer Res 68
  
  Pages: 1119-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] PIK3CA mutations and copy number gains in human lung cancers2008
- Author(s)
  Yamamoto H, Sato M, Gazdar A F., その他
- Journal Title
  
  Cancer Research 68
  
  Pages: 6913-6921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer.2008
- Author(s)
  Kwei KA, Sato M, et al.
- Journal Title
  
  Oncogene 27
  
  Pages: 3635-3640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS2008
- Author(s)
  Guha U, Sato M, Varmus HE, その他
- Journal Title
  
  Proc Natl Acad Sci USA 105
  
  Pages: 14112-14117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS.2008
- Author(s)
  Guha U, Sato M, et al.
- Journal Title
  
  Proc Natl Acad Sci U S A 105
  
  Pages: 14112-14117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Journal Article] PIK3CA mutations and copy number gains in human lung cancers.2008
- Author(s)
  Yamamoto H, Sato M, et al.
- Journal Title
  
  Cancer Res 68
  
  Pages: 6913-6921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590919
[Presentation] LOX は癌遺伝子誘導性細胞老化を機序とする治療標的としての可能性を持つ2023
- Author(s)
  村木那緒、川邉のぞみ、田中一大、砂長則明、佐藤光夫
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19522
[Presentation] 変異型 KRAS によって発現増加する遺伝子 A は肺がんの治療標的としての可能性を持つ2023
- Author(s)
  川邉のぞみ、村木那緒、田中一大、砂長則明、佐藤光夫
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19522
[Presentation] An hTERT/Cdk4-immortalized normal human bronchial epithelial cell line is highly resistant to mutant KRAS-induced senescence2022
- Author(s)
  Nao Muraki, Mitsuo Satoら
- Organizer
  第25回アジア太平洋呼吸器学会（APSR）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02924
[Presentation] Oxytocin receptor is a promising therapeutic target of malignant mesothelioma2022
- Author(s)
  田中一大, 佐藤龍洋, 佐藤光夫, 関戸好孝
- Organizer
  第81回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03689
[Presentation] An hTERT/CDK4-immortalized normal human bronchial epithelial cell line is highly resistant to mutant KRAS-induced senescence2021
- Author(s)
  Nao Muraki, Hinako Doki, Riho Nakai, Mizuki Yamada, Kazuki Komeda, Nozomi Kawabe, Kouhei Matsuoka, Miyoko Matsushima, Tsutomu Kawabe, Ichidai Tanaka, Masahiro Morise and Mitsuo Sato
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology (APSR 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22617
[Presentation] 悪性中皮腫におけるオキシトシン受容体(OXTR)を標的とした新規治療法の開発2021
- Author(s)
  小玉勇太, 田中一大, 佐藤龍洋, 玄崇永, 堀和美, 森瀬昌宏, 佐藤光夫, 関戸好孝
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03689
[Presentation] UHRF1, a regulator of methylation, as a diagnostic and prognostic marker for lung cancer2020
- Author(s)
  佐藤光夫、後藤大輝、上床菜月、中嶋萌夏、小池眞由、川合花穂、米田一樹、小玉　勇太、宮沢亜矢子、田中一大、長谷哲成、森瀬　昌宏、関戸好孝、川部　勤、長谷川好規
- Organizer
  第60回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K22617
[Presentation] Identification of Proteasomal Catalytic Subunit PSMA6 as a Therapeutic Target for Lung Cancer2016
- Author(s)
  佐藤光夫、各務智彦、加藤俊夫、與語直之、長谷哲成、森瀬昌宏、福井高幸、横井香平、Luc Girard 、John Minna、近藤征史、長谷川好規
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-26293197
[Presentation] Cytochrome c oxidase subunit 5a (COX5A) is identified as a potential therapeutic target for lung cancer with high therapeutic index through a pooled shRNA screen2016
- Author(s)
  Kato T, Sato M, Kondo M, Goto , Kato T, Kakumu T, Yogo N, Hase, Morise M, Fukui T, Girard L, Minna JD, Hasegawa Y
- Organizer
  アメリカ癌学会
- Place of Presentation
  ニューオリンズ、アメリカ
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09216
[Presentation] 翻訳開始因子Eurokaryotic initiation factor 2 subunit 2(EIF2S2)は非小細胞肺癌細胞株の増殖を抑制する2016
- Author(s)
  加藤俊夫佐藤光夫,與語直之,;長谷哲成, 森瀬昌宏, 後藤大輝, 宮澤亜矢子, 近藤征史,長谷川好規
- Organizer
  日本肺癌学会
- Place of Presentation
  福岡国際会議場（福岡県、博多市）
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-15K09216
[Presentation] Cytochrome c oxidase subunit 5a (COX5A) is identified as a potential therapeutic target for lung cancer with high therapeutic index through a pooled shRNA screen2016
- Author(s)
  Toshio Kato, Mitsuo Sato, Masashi Kondo, Tomohiko Kakumu, Naoyuki Yogo, Tetsunari Hase, Masahiro Morise, Yoshionori Hasegawa, John D. Minnna, Luc Girard.
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  New Orleans,USa
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15K09216
[Presentation] Cytochrome c oxidase subunit 5a (COX5A) is identified as a potential therapeutic target for lung cancer with high therapeutic index through a pooled shRNA screen2016
- Author(s)
  1.Toshio Kato, Mitsuo Sato, Masashi Kondo, Tomohiko Kakumu, Naoyuki Yogo, Tetsunari Hase, Masahiro Morise, John D Minna, Yoshinori Hasegawa
- Organizer
  アメリカ癌学会年次総会
- Place of Presentation
  ニューオリンズ（アメリカ合衆国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293197
[Presentation] 肺がん治療標的としてのCDK11 の可能性2015
- Author(s)
  各務智彦、佐藤光夫、加藤俊夫、與語直之、長谷哲成、森瀬昌宏、近藤政史、関戸好孝、長谷川好規
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  国際会議場（愛知県名古屋市９
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26293197
[Presentation] 肺がん治療標的としてのCDK11 の可能性2015
- Author(s)
  各務智彦、佐藤光夫、加藤俊夫、與語直之、長谷哲成、森瀬昌宏、近藤政史、関戸好孝、長谷川好規
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  国際会議場（愛知県、名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670416
[Presentation] 非小細胞肺癌治療薬としてのmiR-221とmiR-222の可能性2014
- Author(s)
  佐藤光夫、長谷哲成、近藤征史、長谷川好規
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  神奈川県、横浜市、パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26293197
[Presentation] Why, When and How to Test for EGFR2014
- Author(s)
  Mitsuo Sato
- Organizer
  フィリピン呼吸器学会
- Place of Presentation
  フィリピン、マニラ
- Invited
- Data Source
  KAKENHI-PROJECT-23591145
[Presentation] 非小細胞肺癌におけるmiR-127の機能解析2014
- Author(s)
  丸山英一、各務智弘、梶川茂久、山下良、佐藤光夫、近藤征史、長谷川好規
- Organizer
  第54回呼吸器学会
- Place of Presentation
  大阪
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-23591144
[Presentation] Tumor suppressive roles of miR-221 and miR-222 in lung cancer2014
- Author(s)
  Mitsuo Sato, Ryo Yamashita, Tomohiko Kakumu, Naoyuki Yogo, Tetsunari Hase, Eiichi Maruyama, Yoshitaka Sekido, Masashi Kondo, and Yoshinori Hasegawa
- Organizer
  ENA-2014 Symposium
- Place of Presentation
  バルセロナ、スペイン
- Year and Date
  2014-11-19
- Data Source
  KAKENHI-PROJECT-26670416
[Presentation] Tumor suppressive roles of miR-221 and miR-222 in lung cancer2014
- Author(s)
  Yamashita R, Sato M, Kakumu T, Hase T, Yogo N, Maruyama E, Sekido Y, Kondo M, Hasegawa Y.
- Organizer
  ENA-2014 Symposium
- Place of Presentation
  バルセロナ、スペイン
- Year and Date
  2014-11-19
- Data Source
  KAKENHI-PROJECT-26293197
[Presentation] Functional analysis of miR-127 in non-small-cell lung cancer 非小細胞肺癌におけるmiR-127の機能解析2014
- Author(s)
  丸山　英一、佐藤　光夫、近藤　征史
- Organizer
  日本呼吸器学会
- Place of Presentation
  大阪国際会議場（大阪市北区）
- Data Source
  KAKENHI-PROJECT-23591144
[Presentation] Why, when and how to test for EGFR2014
- Author(s)
  佐藤光夫
- Organizer
  第33回フィリピン呼吸器学会
- Place of Presentation
  フィリピン、マニラ
- Year and Date
  2014-03-08
- Invited
- Data Source
  KAKENHI-PROJECT-23591145
[Presentation] 時計遺伝子Bmal1 ノックダウンはアポトーシスと細胞老化を介して肺癌細胞の増殖を抑制する2013
- Author(s)
  山下　良、佐藤　光夫、長谷川　好規ら
- Organizer
  第54 回日本肺癌学会総会
- Place of Presentation
  ホテルニューオータニ東京(東京都、千代田区）
- Data Source
  KAKENHI-PROJECT-23591145
[Presentation] 時計遺伝子Bmal1ノックダウンはアポトーシスと細胞老化を介して肺癌細胞の増殖を抑性する2013
- Author(s)
  山下　良、佐藤　光夫、近藤　征史
- Organizer
  日本肺癌学会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-23591144
[Presentation] 時計遺伝子Bmal1ノックダウンはアポトーシスと細胞老化を介して肺癌細胞の増殖を抑制する2013
- Author(s)
  山下良、佐藤光夫、長谷川好規, ら
- Organizer
  第54回日本肺癌学会
- Place of Presentation
  ホテルニューオータニ、東京都千代田区
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-23591145
[Presentation] 時計遺伝子Bmal1ノックダウンはアポトーシスと細胞老化を介して肺癌細胞の増殖を抑性する2013
- Author(s)
  山下良、佐藤光夫、Momen Elshazley、長谷哲成、丸山英一、梶川茂久、各務智彦、近藤征史、長谷川好規
- Organizer
  第54回日本肺癌学会
- Place of Presentation
  東京千代田区
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-23591144
[Presentation] Silencing TIMELESS induceds growth suppression, apoptosis and enhanced cytotoxicity of cisplation in H157 lung cancer cell lines2012
- Author(s)
  Yoshida K, Sato M, Hase T, Elshazley M, Yamashita R, Usami N, Taniguchi T, Yokoi K, Nakamura S, Kondo M, Girard L, Minna JD, Hasegawa Y
- Organizer
  2012年アメリカ癌学会
- Place of Presentation
  米国シカゴ
- Year and Date
  2012-04-04
- Data Source
  KAKENHI-PROJECT-23591144
[Presentation] TIMELESS IS OVEREXPRESSED IN LUNG CANCER AND ITS KNOCKDOWN INDUCES APOPTOSIS AND CHEMOSENSITI- ZATION IN LUNG CANCER CELLS2012
- Author(s)
  Yoshida K, Sato M, Hase T, Momen Elshazley, Yamashita R, Usami N, Taniguchi T, Yokoi K, Kondo M,Girard L, Minna J, Hasegawa Y
- Organizer
  5th APLCC (Asian Pacific Lung Cancer Congress)
- Place of Presentation
  Fukuoka Japan
- Data Source
  KAKENHI-PROJECT-23591145
[Presentation] "THE COMBINATION OF FIVE CHANGES (TELOMERASE, P16/RB BYPASS, P53 KNOCKDOWN, KRASV12, C-MYC) TO- GETHER WITH SERUM-INDUCED EPITHELIAL MESENCHYMAL TRANSITION PROGRESSES NORMAL HUMAN BRONCHIAL EPITHELIAL CELLS TO FULL MALIGNANCY "2012
- Author(s)
  Sato M, Larsen J, Lee W, Shames D, Ignacio I. Gazdar W, Shay J, Minna D, Kondo M, Hasegawa Y.
- Organizer
  5th APLCC (Asian Pacific Lung Cancer Congress)
- Place of Presentation
  Fukuoka Japan
- Data Source
  KAKENHI-PROJECT-23591145
[Presentation] THE COMBINATION OF FIVE CHANGES (TELOMERASE, P16/RB BYPASS, P53 KNOCKDOWN, KRASV12, C-MYC) TOGETHERWITH SERUM-INDUCED EPITHELIAL MESENCHYMAL TRANSITION PROGRESSES NORMAL HUMAN BRONCHIAL EPITHELIAL CELLS TO FULL MALIGNANCY2012
- Author(s)
  Mitsuo Sato, Jill E. Larsen, Woochang Lee, David Shames, Ignacio I. Wistuba, Adi F. Gazdar3, Jerry W. Shay, John D. Minna, Masashi Kondo, Yoshinori Hasegawa
- Organizer
  第5回アジア太平洋肺癌会議
- Place of Presentation
  Hilton Fukuoka Sea Hawkホテル、福岡市
- Year and Date
  2012-11-28
- Data Source
  KAKENHI-PROJECT-23591145
[Presentation] STIM1 regulates Ca^2+influx and migration induced by platelet-derived growth factor in human airway smooth muscle cells2012
- Author(s)
  Ito S, Suganuma N, Aso H, Kondo M, Sato M, Hasegawa Y.
- Organizer
  ATS 2012 International Conference
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2012-05-21
- Data Source
  KAKENHI-PROJECT-22590837
[Presentation] Silencing of TIMELESS induces growth suppression, apoptosis and enhanced cytotoxicity of cisplatin in H157 lung cancer cells2012
- Author(s)
  Kenya Yoshida, Mitsuo Sato, Tetsunari Hase, Momen Elshazley,
- Organizer
  アメリカ癌学会
- Place of Presentation
  シカゴ　アメリカ
- Data Source
  KAKENHI-PROJECT-23591144
[Presentation] Transient but Not Stable ZEB1 Knockdown Dramatically Inhibits Growth of Malignant Pleural Mesothelioma Cells: Implication of EpCAM Up-regulation Induced by ZEB1 Knockdown2011
- Author(s)
  M. Horio, M. Sato, Y. Takeyama, T. Hase, E. Momen, K. Yoshida, Y. Sekido, M. Kondo, A.F. Gazdar, J.D. Minna, Y. Hasegawa
- Organizer
  第14回世界肺がん学会
- Place of Presentation
  オランダ、アムステルダム
- Data Source
  KAKENHI-PROJECT-23591145
[Presentation] Transient but not stable ZEB1 knockdown dramatically inhibits growth of malignant pleural mesothelioma cells2011
- Author(s)
  Horio M, Sato M, Takeyama Y, Elshazley M, Yamashita R, Hase T, Yoshida K, Usami N, Yokoi K, Sekido Y, Kondo M, Toyokuni S, Gazdar AF, Minna JD, Hasegawa Y
- Organizer
  第14回世界肺癌学会
- Place of Presentation
  オランダ、アムステルダム
- Year and Date
  2011-07-04
- Data Source
  KAKENHI-PROJECT-23591145
[Presentation] Knockdown of ZEB1, a master EMT gene, suppresses anchorage-independent cell growth of lung cancer cells.2010
- Author(s)
  佐藤光夫, ら
- Organizer
  第101回アメリカ癌学会総会
- Place of Presentation
  ワシントンDC、アメリカ
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-20590919
[Presentation] Knockdown of ZEB1, a master EMT gene, suppresses growth of pleural mesothelioma cell lines.2010
- Author(s)
  堀尾美穂子、佐藤光夫, ら
- Organizer
  第101回アメリカ癌学会総会
- Place of Presentation
  ワシントンDG、アメリカ
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-20590919
[Presentation] Knockdown of ZEB1, a master EMT gene, suppresses anchorage-independent cell growth of lung cancer cells.2010
- Author(s)
  佐藤光夫, ら, et al.
- Organizer
  第101回アメリカ癌学会総会、2010年4月、ワシントンDC,アメリカ合衆国
- Place of Presentation
  ポスター発表
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-20590919
[Presentation] 5つの遺伝子変化と血清によるEMT誘導は正常気管支上皮細胞を完全にがん化させる2010
- Author(s)
  佐藤光夫, ら
- Organizer
  第69日本癌学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590919
[Presentation] 大阪、5つの遺伝子変化と血清によるEMT誘導は正常気管支上皮細胞を完全にがん化させる2010
- Author(s)
  佐藤光夫, ら
- Organizer
  第69回日本癌学会学術総会、2010年9月
- Place of Presentation
  口頭発表
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590919
[Presentation] Knockdown of ZEB1, a master EMT gene, suppresses growth of pleural mesothelioma cell lines.2010
- Author(s)
  Mihoko Horio, Mitsuo Sato, et al.
- Organizer
  第101回アメリカ癌学会総会、2010年4月、ワシントンDC,アメリカ合衆国
- Place of Presentation
  ポスター発表
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-20590919
[Presentation] STIM1 regulates Ca2+ influx and migration induced by platelet-derived growth factor in human airway smooth muscle cells.
- Author(s)
  Ito S, Suganuma N, Aso H, Kondo M, Sato M, Hasegawa Y.
- Organizer
  ATS 2012 International Conference
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-22590837

1. HASE Tetsunari (30621635)

# of Collaborated Projects: 7 results

# of Collaborated Products: 10 results
2. KONDO Masashi (00378077)

# of Collaborated Projects: 6 results

# of Collaborated Products: 30 results
3. TANAKA ICHIDAI (40809810)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
4. YUKAWA Hiroshi (30634646)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
5. ITO Satoru (60378073)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. ANDO Yuichi (10360083)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. SAWAKI Masataka (20402597)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. MITSUMA Ayako (10467326)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. KAWADA Kenji (30418743)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. HASEGAWA Yoshinori (20270986)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
11. IMAIZUMI Kazuyoshi (50362257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
12. YOKOI Kohei (60378007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. YOGO Naoyuki (70817874)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
14. 芳川豊史 (00452334)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 川口晃司 (10402611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 川井久美 (50362231)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. 関戸好孝 (00311712)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
18. SOKABE Masahiro (10093428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 橋本直純 (30378020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
20. 山本直樹 (00267957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 星雅人 (40633996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 成瀬恵治 (40252233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 松井佑介 (90761495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 森瀬昌宏 (00612756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. 松原大祐 (80415554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 田口歩 (50817567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 佐藤龍洋 (70547893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 堀和美 (31000177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. Miyazawa Ayako

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
30. KAWABE Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. MATSUSHIMA Miyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 砂長則明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 田中宏昌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SATO Mitsuo 佐藤 光夫

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MAPKシグナル伝達経路を負に制御するフォスファターゼ遺伝子を標的とする肺癌治療Principal Investigator

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長鎖非翻訳RNAを標的とする変異KRAS肺癌の合成致死治療の開発Principal Investigator

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ドライバー癌遺伝子誘導性の細胞老化を作用機序とする変異KRAS肺癌の創薬研究Principal Investigator

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Development of therapeutics for lung cancer that target factors stabilizing epithelial-to-mesenchymal transitionPrincipal Investigator

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Development of novel therapeutics that utilize driver oncogene-induced senescencePrincipal Investigator

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Identification of driver genes in lung cancer through a semi-genome wide shRNA library screen based on anoikis resistance phenotypePrincipal Investigator

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Development of a novel therapeutic strategy targeting genes contributing to forming cluster in EGFR mutated lung cancerPrincipal Investigator

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SATO Mitsuo 佐藤光夫