Yamaguchi Yoshihiro 山口良弘

… Alternative Names

山口良弘ヤマグチヨシヒロ

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Researcher Number	00737009
Other IDs	https://orcid.org/0000-0003-4663-6963
Affiliation (Current)	2026: 大阪公立大学, 大学院理学研究科, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪公立大学, 大学院理学研究科, 准教授 2019 – 2021: 大阪市立大学, 大学院理学研究科, 准教授 2014 – 2018: 大阪市立大学, 複合先端研究機構, 特任准教授(テニュアトラック)
Review Section/Research Field	Principal Investigator Basic Section 38020:Applied microbiology-related / Applied biochemistry / Applied microbiology Except Principal Investigator Bacteriology (including mycology) / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator Toxin-antitoxin system / MqsR / バイオテクノロジー / 応用微生物 / celll division / cytoskeleton proteins / Pull-down assay / FtsZ / パーシスター / suppresor mutant … More / RNA polymerase / 大腸菌 / アミノ酸合成 / γ-グルタミルアミントランスシクロラーぜ / toxin-antitoxin system / 生育制御 / endoribonuclease / biofilm / MqsA / バイオフィルム / トキシン・アンチトキシンシステム / Escherichia coli / Biofilm / バイオリアクター / Saccharomyces cerevisiae / Yeast / yeast / MazF / SPP system / 遺伝子工学 / 酵素学 / 応用微生物学 / 分子生物 / 分子生物学 / 生化学 … More Except Principal Investigator 下痢 / 食品 / 細菌 / 病原性 / 宿主特異性 / ETEC / 接着因子 / 人獣共通感染症 / 腸管定着因子 / 下痢原性大腸菌 / 腸管毒素原性大腸菌 / プロバイオティクス / 線虫 / 炎症性腸疾患 / 分散接着性大腸菌 / 生菌製剤 / 炎症抑制 / 炎症性サイトカイン / 腸内細菌 / 炎症 Less

分散接着性大腸菌による腸炎抑制メカニズム解明とプロバイオティクスへの応用
- Principal Investigator
  
  中台枝里子 (鹿毛枝里子)
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyoto University
  Osaka Metropolitan University
  Osaka City University
大腸菌の新規 YecE-YecD toxin-antitoxin system の機能解析Principal Investigator
- Principal Investigator
  
  山口良弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Osaka Metropolitan University
Characterization of the novel yafD-yafE toxin-antitoxin systemPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yoshihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Mechanism of biofilm formation and cell death mediated with MqsA in Escherichia coliPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yoshihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Osaka City University
Validation on the possible zoonotic transmission by a novel colonization factor found on pandemic enterotoxigenic E. coli serogroup O169
- Principal Investigator
  
  Nishikawa Yoshikazu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Osaka City University
Development a novel method to produce a single protein in yeastPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yoshihiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied biochemistry
- Research Institution
  Osaka City University
An endogenous protein inhibitor, YjhX (TopI), for topoisomerase I from Escherichia coliPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yoshihiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Applied microbiology
- Research Institution
  Osaka City University

All 2025 2020 2019 2018 2017 2015 Other

All Journal Article Presentation

[Journal Article] An atypical kappa-class chaperone-usher fimbriae of a human enterotoxigenic Escherichia coli strain shows multi-host adherence and distinct phylogenetic feature.2025
- Author(s)
  Inoue H, Tanimoto Y, Zheng D, Ban-Furukawa E, Inoue M, Omori Y, Yamaguchi Y, Tachibana T, Aso H, Zhang W, Kage-Nakadai E, Nishikawa Y, Wada T.
- Journal Title
  
  Microbiology and Immunology
  
  Volume: - Issue: 5 Pages: 270-279
- DOI
  10.1111/1348-0421.13208
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18391, KAKENHI-PROJECT-23K21631, KAKENHI-PROJECT-23K16319
[Journal Article] Diffusely adherent Escherichia coli strains isolated from healthy carriers suppress cytokine secretions of epithelial cells stimulated by inflammatory substances2018
- Author(s)
  Tanimoto Yoshihiko、Tamai Sayaka、Matsuzaki Takehiro、Takeuchi Narumi、Noju Takumi、Yanagida Saki、Kage-Nakadai Eriko、Yamaguchi Yoshihiro、Kodama Toshio、Nakamura Shota、Motooka Daisuke、Iida Tetsuya、Nishikawa Yoshikazu
- Journal Title
  
  Infection and Immunity
  
  Volume: 87 Issue: 1 Pages: e00683-18
- DOI
  10.1128/iai.00683-18
- NAID
  120006548613
- URL
  https://ocu-omu.repo.nii.ac.jp/records/2019889
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08829, KAKENHI-PROJECT-18K10998, KAKENHI-PROJECT-17H04078
[Journal Article] An endogenous protein inhibitor, YjhX (TopAI), for topoisomerase I from Escherichia coli.2015
- Author(s)
  Yoshihiro Yamaguchi and Masayori Inouye
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 43 Pages: 10387-10396
- DOI
  10.1093/nar/gkv1197
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26892025
[Presentation] Genes implicated in the suppression of IL-8 secretion by diffusely adherent Escherichia coli2020
- Author(s)
  202.Takaura, A, Tanimoto, Y., Odani, A., Shinya, S., Tomonori Kamiya[2], Naoko Ohtani, Yoshihiro Yamaguchi, Tomomi Komura, Eriko Kage-Nakadai, Yoshikazu Nishikawa
- Organizer
  第93回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17H04078
[Presentation] Seroepidemiology on novel colonization factor of enterotoxigenic E. coli O169 in pigs and cattle2020
- Author(s)
  201.Inoue, M., Zheng, D., Omori, Y., Komatsu, K., Yamaguchi, Y., Miyata, M., Wada, T., Aso, H., Kage-Nakadai, E., and Nishikawa, Y
- Organizer
  第93回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17H04078
[Presentation] トランスポゾン挿入により上皮細胞に対する炎症性サイトカイン分泌抑制機能を喪失した分散接着性大腸菌2019
- Author(s)
  196.髙浦彩那、谷本佳彦、小谷篤幸、新家早絵、髙山夏行、山口良弘、小村智美、中台（鹿毛）枝里子、西川禎一
- Organizer
  第72回日本細菌学会関西支部会
- Data Source
  KAKENHI-PROJECT-17H04078
[Presentation] ヒト腸管毒素原性大腸菌O169:H41の新規定着因子に対する抗体のブタおよびウシにおける保有状況2019
- Author(s)
  195.井上三代子、小松加奈、鄭　冬明、大森裕子、山口良弘、宮田真人、和田崇之、中台（鹿毛）枝里子、西川禎一
- Organizer
  第72回日本細菌学会関西支部会
- Data Source
  KAKENHI-PROJECT-17H04078
[Presentation] Diffusely adherent Escherichia coli (DAEC) strains isolated from healthy carriers inhibit IL-8 secretion of epithelial cells by the type VI secretion system (T6SS)2017
- Author(s)
  Takeuchi, N., Tanimoto, Y., Tamai, S., Yanagida, S., Yamaguchi, Y., Kage-Nakadai, E., and Nishikawa, Y.
- Organizer
  The 16th Awaji International Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04078
[Presentation] 培養細胞からの炎症性サイトカイン分泌に対する分散接着性大腸菌の抑制機構2017
- Author(s)
  柳田　咲、玉井沙也加、能重　匠、谷本佳彦、松崎壮宏、竹内成美、中臺枝里子、山口良弘、児玉年央、飯田哲也、西川禎一
- Organizer
  第71回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17H04078
[Presentation] MqsR を介した目的タンパク質のみを生産可能な発現系の構築2017
- Author(s)
  釋真緒、井上正順、山口良弘
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-16K14906
[Presentation] 上皮細胞からのサイトカイン分泌に対する分散接着性大腸菌の抑制効果に関与する因子の探索2017
- Author(s)
  谷本佳彦、竹内成美、玉井沙也加、柳田　咲、中台枝里子、山口良弘、西川禎一
- Organizer
  第38回日本食品微生物学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04078
[Presentation] SymE, a hexameric E. coli toxin, is a DNA gyrase inhibitor in E. coli
- Author(s)
  山口良弘
- Organizer
  日本農芸化学会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-27 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26892025

1. 中台枝里子 (40453790)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. Nishikawa Yoshikazu (60183539)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. 大谷直子 (50275195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 和田崇之 (70332450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 立花太郎 (80311752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山崎伸二 (70221653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 増田俊哉 (10219339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 谷本佳彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamaguchi Yoshihiro 山口 良弘

山口 良弘 ヤマグチ ヨシヒロ

Research Projects

Research Products

Co-Researchers

分散接着性大腸菌による腸炎抑制メカニズム解明とプロバイオティクスへの応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

大腸菌の新規 YecE-YecD toxin-antitoxin system の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Characterization of the novel yafD-yafE toxin-antitoxin systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of biofilm formation and cell death mediated with MqsA in Escherichia coliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Validation on the possible zoonotic transmission by a novel colonization factor found on pandemic enterotoxigenic E. coli serogroup O169

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development a novel method to produce a single protein in yeastPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An endogenous protein inhibitor, YjhX (TopI), for topoisomerase I from Escherichia coliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An atypical kappa-class chaperone-usher fimbriae of a human enterotoxigenic Escherichia coli strain shows multi-host adherence and distinct phylogenetic feature.2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diffusely adherent Escherichia coli strains isolated from healthy carriers suppress cytokine secretions of epithelial cells stimulated by inflammatory substances2018

Author(s)

Journal Title

DOI

NAID

URL

Language

Data Source

[Journal Article] An endogenous protein inhibitor, YjhX (TopAI), for topoisomerase I from Escherichia coli.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Genes implicated in the suppression of IL-8 secretion by diffusely adherent Escherichia coli2020

Author(s)

Organizer

Data Source

[Presentation] Seroepidemiology on novel colonization factor of enterotoxigenic E. coli O169 in pigs and cattle2020

Author(s)

Organizer

Data Source

[Presentation] トランスポゾン挿入により上皮細胞に対する炎症性サイトカイン分泌抑制機能を喪失した分散接着性大腸菌2019

Author(s)

Organizer

Data Source

[Presentation] ヒト腸管毒素原性大腸菌O169:H41の新規定着因子に対する抗体のブタおよびウシにおける保有状況2019

Author(s)

Organizer

Yamaguchi Yoshihiro 山口良弘

山口良弘ヤマグチヨシヒロ