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Ohtani Naoko  大谷 直子

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OHTANI Naoko  大谷 直子

藤田 直子  フジタ ナオコ

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Researcher Number 50275195
Other IDs
Affiliation (Current) 2023: 大阪公立大学, 大学院医学研究科, 教授
Affiliation (based on the past Project Information) *help 2022: 大阪公立大学, 大学院医学研究科, 教授
2017 – 2021: 大阪市立大学, 大学院医学研究科, 教授
2016: 東京理科大学, 理工学部応用生物科学科, 教授
2014 – 2015: 東京理科大学, 理工学部, 教授
2013: 公益財団法人がん研究会, がん研究所, 主任研究員 … More
2013: 公益財団法人がん研究会, がん研究所がん生物部, 主任研究員
2012: 公益財団法人がん研究会, がん研究所 がん生物部, 主任研究員
2011: 公益財団法人がん研究会, がん研究所・がん生物部, 主任研究員
2010: Japanese Foundation For Cancer Research, 癌研究所がん生物部, 主任研究員
2010: 財団法人癌研究会, 癌研究所がん生物部, 主任研究員
2009: Japanese Foundation For Cancer Research, 主任研究員
2009: Japanese Foundation For Cancer Research, 財団法人癌研究所, 主任研究員
2008: Japanese Foundation For Cancer Research, がん生物部, 主任研究員
2008: (財)癌研究会, 癌研究所, 主任研究員
2008: Japanese Foundation For Cancer Research, 癌研究所がん生物部, 主任研究員
2007 – 2008: The University of Tokushima, Institute For Genome Research, Associate Professor
2004 – 2006: 徳島大学, ゲノム機能研究センター, 助教授
1998: 京都府立医大, 医学部, 助手
1997: 京都府立医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Ophthalmology / Applied health science / Carcinogenesis / Dermatology / Applied health science / Basic Section 59020:Sports sciences-related / Tumor biology / Basic Section 59040:Nutrition science and health science-related
Except Principal Investigator
Biological Sciences … More / Dermatology / Basic Section 59040:Nutrition science and health science-related / Hygiene / Gastroenterology Less
Keywords
Principal Investigator
イメージング / 細胞老化 / 炎症性サイトカイン / 肥満 / がん微小環境 / 運動 / p21 / p16 / がん予防 / 網膜芽細胞腫 … More / RB遺伝子 / メチル化 / 発現 / 生活習慣病 / 概日リズム / 発癌 / p53 / RB / 慨日リズム / p16^<INK4a> / p21^<Waf1/Cip1> / メタボリックストレス / 炎症とがん / 癌微小環境 / 肝がん / p16^<INK4a>遺伝子 / 皮膚癌 / p16^<Ink4a>遺伝子 / 可視化 / BAC / p16^<INK4a> gene / bioluminescence in vivo imaging / skin cancer / 規則的運動 / 肥満誘導性肝癌 / 臓器連関 / 細胞老化随伴分泌現象 / IL-33 / 制御性T細胞 / 肥満関連肝がん / 肝星細胞 / SASP / 肥満誘導性肝がん / メタボライト … More
Except Principal Investigator
発がん / 有棘細胞癌 / 日光角化症 / 脂漏性角化症 / 免疫染色 / NADPH oxidase 1 / Nox organizer 1 / SIRT1 / gadd45遺伝子 / プロモーター / Δ^<12>-プロスタグランディンJ_2 / 紫外線 / ケルセチン / gadd45 / DNA修復 / 化学予防 / p16^<INK4a> / RB / EBウイルス / LMP1 / CRM1 / 細胞周期 / 癌抑制 / 皮膚腫瘍学 / 表皮角化細胞 / エピジェネティクス / 癌細胞 / 細胞老化 / p53 / HICl / FGFR3 / セネッセンス / γ-H2AX / 造血幹細胞 / 幹細胞ニッチ / 幹細胞代謝 / メタボローム解析 / 単一細胞トランスクリプトーム解析 / 低酸素 / ストレス応答 / SASP / in vivoイメージング / メタボロミクス / ニッチ / 老化 / 巨核球 / 感染応答 / 遺伝子改変マウス / 消化管粘膜 / 自然免疫応答 / 炎症 / TNF-α / Gene-targeted mice / Gastrointestinal mucosa / Innate immunity / Inflammation / Carcinogenesis / tumor necrosis factor-alpha / 基底細胞癌 / ボーエン病 / 細胞周期関連遺伝子 / p27 / squamous cell carcinoma / basal cell carcinoma / Bowen's disease / actinic keratosis / seborrheic keratosis / cell cycle / immunohistochemical analysis / ミトコンドリア / 脂肪肝 / 肝発がん / 分散接着性大腸菌 / 炎症性サイトカイン / プロバイオティクス / 炎症抑制 / 炎症性腸疾患 Less
  • Research Projects

    (18 results)
  • Research Products

    (140 results)
  • Co-Researchers

    (53 People)
  •  規則的な運動による肝がん抑制機構の解明:オンコメタボライトの分解機構に着目してPrincipal Investigator

    • Principal Investigator
      大谷 直子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Osaka Metropolitan University
  •  Clarify the role of mitochondria function on the development of fatty liver and hepatic carcinogenesis by targeting Apop-1

    • Principal Investigator
      福尾 惠介
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Mukogawa Women's University
  •  分散接着性大腸菌による腸炎抑制メカニズム解明とプロバイオティクスへの応用

    • Principal Investigator
      中台 枝里子 (鹿毛枝里子)
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Osaka Metropolitan University
      Osaka City University
  •  The molecular mechanism of the inhibitory effect of liver cancer development via inter-organ relationship by regular exercise: its application to cancer preventionPrincipal Investigator

    • Principal Investigator
      Ohtani Naoko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Osaka City University
  •  The mechanism of obesity-associated liver cancer progression through cytokine cross-talk in tumor microenvironment.Principal Investigator

    • Principal Investigator
      Ohtani Naoko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Osaka City University
      Tokyo University of Science
  •  The effect of regular exercise on obesity-associated liver cancer from the aspect of gut microbiota and lipid metabolitesPrincipal Investigator

    • Principal Investigator
      Ohtani Naoko
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied health science
    • Research Institution
      Tokyo University of Science
  •  Aging and anti-aging mechanisms in niche-hematopoietic stem cell interaction

    • Principal Investigator
      TAKUBO Keiyo
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      National Center for Global Health and Medicine
  •  The molecular mechanism of senescence-associated prolongation of inflammatory signaling and its effect on cancer micro-environments.Principal Investigator

    • Principal Investigator
      OHTANI Naoko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Carcinogenesis
    • Research Institution
      Japanese Foundation for Cancer Research
  •  メタボリックストレス応答におけるCDKインヒビターの役割Principal Investigator

    • Principal Investigator
      大谷 直子
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
  •  分子イメージングを利用したCDKインヒビターp21の生体内機能の解明Principal Investigator

    • Principal Investigator
      大谷 直子
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Mechanism of Tumor formation by deregulated circadian rhythm and strategy for its preventionPrincipal Investigator

    • Principal Investigator
      OHTANI Naoko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied health science
    • Research Institution
      Japanese Foundation For Cancer Research
  •  The regulation and abnormalities of the epigenetics on epidermal keratinocytes

    • Principal Investigator
      KUBO Yoshiaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokushima
  •  Analysis and pathophysiology of dysregulated expression of the Noxl gene using Noxl knockout mice

    • Principal Investigator
      ROKUTAN Kazuhito
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokushima
  •  Molecular abnormalities of cell cycle regulations in epidermal keratinocytes for the clinical applications

    • Principal Investigator
      KUBO Yoshiaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      The University of Tokushima
  •  EBウイルスLMP1癌蛋白によるp16^<INK4a>/RB経路阻害機構の解明

    • Principal Investigator
      HARA Eiji
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Induction of p16^<INK4a> gene expression by oncogenic stress is involved in the tumor suppression mechanism of skin cancerPrincipal Investigator

    • Principal Investigator
      OHTANI Naoko
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      University of Tokushima
  •  網膜芽細胞腫におけるRB遺伝子の過剰メチル化による失活機構の解明Principal Investigator

    • Principal Investigator
      藤田 直子
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Ophthalmology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  DNA修復遺伝子gadd45の誘導物質の検索-新しい化学予防物質の検索法の確立に向けて-

    • Principal Investigator
      酒井 敏行
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2006 2005 Other

All Journal Article Presentation Book

  • [Book] 消化器疾患の最新医療 トピックス 腸内細菌と消化器がん2018

    • Author(s)
      田尻久雄(編集顧問)大谷直子(分担執筆)
    • Total Pages
      485
    • Publisher
      寺田国際事務所/先端医療技術研究所
    • ISBN
      9784925089616
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Book] Chronic Inflammation (Msayuki Miyasaka and Kiyoshi Takatsu Editors) Part III No 15. Cellular Senescence as a Novel Mechanism of Chronic Inflammation and Cancer Progression2016

    • Author(s)
      Naoko Ohtani
    • Total Pages
      702
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Book] Chronic Inflammation (Msayuki Miyasaka and Kiyoshi Takatsu Editors) Part III No 15. Cellular Senescence as a Novel Mechanism of Chronic Inflammation and Cancer Progression2016

    • Author(s)
      Naoko Ohtani
    • Total Pages
      702
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Book] 組織幹細胞の老化(佐方功幸、稲垣昌樹、岸本武雄 編集)(細胞周期フロンティア)2010

    • Author(s)
      大谷直子 執筆担当
    • Publisher
      共立出版
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization2019

    • Author(s)
      M. Iwamoto, W. Saso, R. Sugiyama, K. Ishii, M. Ohki, S. Nagamori, R. Suzuki, H. Aizaki, A. Ryo, J-H Yun, S-Y Park, N. Ohtani, M. Muramatsu, S. Iwami, Y. Tanaka, C. Sureau, T. Wakita and K. Watashi
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 116 Pages: 1-6

    • DOI

      10.1073/pnas.1811064116

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05819, KAKENHI-PROJECT-16H04845, KAKENHI-PROJECT-18H01139, KAKENHI-PROJECT-16KT0111, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-15KT0107, KAKENHI-PROJECT-16K08825, KAKENHI-PROJECT-16K13777, KAKENHI-PROJECT-19K16672, KAKENHI-PROJECT-18H02413, KAKENHI-PROJECT-19J21455, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
  • [Journal Article] Role of the Gut-Liver Axis in Liver Inflammation, Fibrosis, and Cancer: A Special Focus on the Gut Microbiota Relationship2019

    • Author(s)
      Ohtani N, Kawada N.
    • Journal Title

      Hepatology Communications

      Volume: 3 Pages: 456-470

    • DOI

      10.1002/hep4.1331

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-16H04699
  • [Journal Article] The aryl hydrocarbon receptor-cytochrome P450 1A1 pathway controls lipid accumulation and enhances the permissiveness for hepatitis C virus assembly2018

    • Author(s)
      Ohashi Hirofumi、Nishioka Kazane、Nakajima Syo、Kim Sulyi、Suzuki Ryosuke、Aizaki Hideki、Fukasawa Masayoshi、Kamisuki Shinji、Sugawara Fumio、Ohtani Naoko、Muramatsu Masamichi、Wakita Takaji、Watashi Koichi
    • Journal Title

      J Biol Chem

      Volume: 293 Pages: 19559-19571

    • DOI

      10.1074/jbc.ra118.005033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-18K05343, KAKENHI-PROJECT-18J14277, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
  • [Journal Article] Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.2018

    • Author(s)
      Takahashi A, Loo TM, Okada R, Kamachi F, Watanabe Y, Wakita M, Watanabe S, Kawamoto S, Miyata K, Barber GN, Ohtani N, Hara E
    • Journal Title

      Nat Commun

      Volume: 9 Pages: 1-12

    • DOI

      10.1038/s41467-018-03555-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19031, KAKENHI-PUBLICLY-17H05628, KAKENHI-PROJECT-16H04700, KAKENHI-PROJECT-17K19618, KAKENHI-PROJECT-18K15065, KAKENHI-PROJECT-16H04699
  • [Journal Article] Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide.2018

    • Author(s)
      Kaneko M, Futamura Y, Tsukuda S, Kondoh Y, Sekine T, Hirano H, Fukano K, Ohashi H, Saso W, Morishita R, Matsunaga S, Kawai F, Ryo A, Park S-Y, Suzuki R, Aizaki H, Ohtani N, Sureau C, Wakita T, Osada H, Watashi K
    • Journal Title

      Sci Rep

      Volume: 8 Pages: 1-13

    • DOI

      10.1038/s41598-018-20987-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05366, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
  • [Journal Article] Functional association of cellular microtubules with viral capsid assembly supports efficient hepatitis B virus replication2017

    • Author(s)
      Iwamoto M、Cai D、Sugiyama M、Suzuki R、Aizaki H、Ryo A、Ohtani N、Tanaka Y、Mizokami M、Wakita T、Guo H、Watashi K
    • Journal Title

      Sci Rep.

      Volume: 7 Pages: 1-10

    • DOI

      10.1038/s41598-017-11015-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
  • [Journal Article] Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity.2017

    • Author(s)
      Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Iwama A, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo MM, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N.
    • Journal Title

      Cancer Discov

      Volume: 7 Pages: 522-538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Journal Article] Gut microbiota promotes obesity-associated liver cancer throug PGE2-mediated suppression of antitumor immunity2017

    • Author(s)
      Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Iwama A, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo MM, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N
    • Journal Title

      Cancer Discovery

      Volume: in press Pages: 522-538

    • DOI

      10.1158/2159-8290.cd-16-0932

    • Description
      Epub ahead of print
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-14J06998, KAKENHI-PROJECT-15K12709, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-26670030, KAKENHI-PROJECT-15K19031, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-16H04699
  • [Journal Article] Impact of senescence-associated secretory phenotype and its potential as a therapeutic target for senescence-associated diseases2017

    • Author(s)
      Watabnabe, S., Kawamoto, S., Ohtani, N., & Hara, E.
    • Journal Title

      Cancer Sci.

      Volume: - Pages: 563-569

    • DOI

      10.1111/cas.13184

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-26430116, KAKENHI-PROJECT-16H04699
  • [Journal Article] Dysregulation of the Bmi-1/p16 pathway provokes an aging-associated decline of submandibular gland function.2015

    • Author(s)
      Yamakoshi K, Katano S, Iida M, Kimura H, Okuma A, Ikemoto-Uezumi M, Ohtani N, Hara E, Maruyama M.
    • Journal Title

      Aging Cell.

      Volume: - Pages: 616-624

    • DOI

      10.1111/acel.12337

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J10280, KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-15K12709, KAKENHI-PROJECT-25861349
  • [Journal Article] Crosstalk between the RB-pathway and AKT signaling forms a Quiescence-Senescence switch.2014

    • Author(s)
      Imai, Y., Takahashi, A., Hanyuu, A., Hori, S., Sato, S., Naka, K., Hirao, A., Ohtani, N., Hara, E.
    • Journal Title

      Cell Rep.

      Volume: 7 Pages: 194-207

    • DOI

      10.1016/j.celrep.2014.03.006

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-23300343, KAKENHI-PROJECT-23300352, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24650625, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25290046, KAKENHI-PROJECT-26250028
  • [Journal Article] Crosstalk between RB-pathway and AKT signaling forms a Quiescence-Senescence switch2014

    • Author(s)
      Imai Y, Takahashi A, Hanyuu A, Hori S, Sato S, Naka K, Hirao A, Ohtani N, and Hara E
    • Journal Title

      Cell Reports 10

      Volume: 7 Pages: 194-207

    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] Roles and mechanisms of cellular senescence in regulation of tissue homeostasis2013

    • Author(s)
      Ohtani N and Hara E
    • Journal Title

      Cancer Science

      Volume: 104 Pages: 525-30

    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome2013

    • Author(s)
      Yoshimoto S, Loo TM, Atarashi K, Kanda H, Sato S, Oyadomari S, Iwakura Y, Oshima K, Morita H, Hattori M, Honda K, Ishikawa Y, Hara E, Ohtani N
    • Journal Title

      Nature

      Volume: 499 Pages: 97-101

    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] 細胞老化による発がん制御-細胞老化の功罪-2013

    • Author(s)
      佐藤正大、大谷直子、原 英二
    • Journal Title

      実験医学

      Volume: 31 Pages: 733-738

    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] マイクロバイオームとがん2013

    • Author(s)
      大谷直子、原 英二
    • Journal Title

      医学のあゆみ

      Volume: 246 Pages: 1095-1101

    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] Antitumor Impact of p14ARF on Gefitinib-Resistant Non-Small Cell Lung Cancers2013

    • Author(s)
      Saito K, Takigawa N, Ohtani N, Iioka H, Tomita Y, Ueda R, Fukuoka J, Kuwahara K, Ichihara E, Kiura K, Kondo E
    • Journal Title

      Mol Cancer Ther

      Volume: 12 Pages: 1616-28

    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] Antitumor impact of p14ARF on gefitinib-resistant non-small cell lung cancers. Mol Cancer Ther. 2013 Aug;12(8):1616-28. doi:2013

    • Author(s)
      Saito K, Takigawa N, Ohtani N, Iioka H, Tomita Y, Ueda R, Fukuoka J, Kuwahara K, Ichihara E, Kiura K, Kondo E.
    • Journal Title

      Mol Cancer Ther.

      Volume: 12 Pages: 1-13

    • DOI

      10.1158/1535-7163.mct-12-1239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300343, KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24590388, KAKENHI-PUBLICLY-25112716, KAKENHI-PROJECT-25290062, KAKENHI-PROJECT-25670263
  • [Journal Article] Cellular senescence : a double-edged sword in the fight against cancer2012

    • Author(s)
      Ohtani N, Takahashi A, Mann D.J., Hara E.
    • Journal Title

      Experimental Dermatology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22019042
  • [Journal Article] DNA Damage Signaling Triggers Degradation of Histo Methyltransferases through APC/C^<Cdh1> in Senescent Cells2012

    • Author(s)
      Takahashi A, Imai Y, Yamakoshi K, Kuninaka S, Ohtani N, Yoshimoto S, Hori S, Tachibana M, Anderton E, Takeuchi T, Shinkai Y, Peters G, Saya H, Hara E
    • Journal Title

      Molecular Cell

      Volume: Vol 45 Pages: 123-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22019042
  • [Journal Article] Cellular senescence : a double-edged sword in the fight against cancer2012

    • Author(s)
      Ohtani N, Takahashi A, Mann D.J., Hara E
    • Journal Title

      Experimental Dermatology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] DNA Damage Signaling Triggers Degradation of Histone Methyltransferases through APC/C^<Cdh1> in Senescent Cells2012

    • Author(s)
      Takahashi A, Imai Y, Yamakoshi K, Kuninaka S, Ohtani N, Yoshimoto S, Hori S, Tachibana M, Anderton E, Takeuchi T, Shinkai Y, Peters G, Saya H, Hara E
    • Journal Title

      Molecular Cell

      Volume: Vol 45 Pages: 123-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] Cellular senescence: a double-edged sword in the fight against cancer.2012

    • Author(s)
      Ohtani N, Takahashi A, Mann DJ, Hara E.
    • Journal Title

      Experimental Dermatology

      Volume: 21, supplement 1 Pages: 1-4

    • DOI

      10.1111/j.1600-0625.2012.01493.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] 細胞老化のがん抑制と発癌促進における役割2011

    • Author(s)
      大谷直子、原英二
    • Journal Title

      実験医学

      Volume: vol.29 Pages: 85-91

    • Data Source
      KAKENHI-PROJECT-23300343
  • [Journal Article] 細胞老化のがん抑制と発癌促進における役割2011

    • Author(s)
      大谷直子、原英二
    • Journal Title

      実験医学

      Volume: vol.29 Pages: 85-91

    • Data Source
      KAKENHI-PUBLICLY-22019042
  • [Journal Article] Intrinsic cooperation between p16^<Ink4a> and p21^<Waf/Cip1> in the onset of cellular senescence and tumor suppression in vivo.2010

    • Author(s)
      Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Hirao A, Yanagi S, Fukami K, Ishikawa Y, Sone S., Hara E., Ohtani N.
    • Journal Title

      Cancer Research

      Volume: 70 Pages: 9381-9390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] Real-time in vivo imaging of p16^<Ink4a> gene expression : a new approach to st〓senescence stress signaling in living animals2010

    • Author(s)
      Ohtani N, Yamakoshi K, Takahashi A, Hara E.
    • Journal Title

      Cell Division 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20058027
  • [Journal Article] Real-time in vivo imaging of p16^<Ink4a> gene expression : a new approach to study senescence stress signaling in living animals.2010

    • Author(s)
      Ohtani N, Yamakoshi K, Takahashi A, Hara E
    • Journal Title

      Cell Division 5:1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] Intrinsic cooperation between p16^<Ink4a> and p21^<Waf/Cip1> in the onset of cellular senescence and tumor suppression in vivo.2010

    • Author(s)
      Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Hirao A, Yanagi S, Fukami K, Ishikawa Y, Sone S., Hara E., Ohtani N
    • Journal Title

      Cancer Research 70

      Pages: 9381-9390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] Intrinsic cooperation between p16^<Ink4a> and p21^<Waf/Cip1> in the onset of cellular senescence and tumor suppression in vivo.2010

    • Author(s)
      Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Hirao A, Yanagi S, Fukami K, Ishikawa Y, Sone S., Hara E., Ohtani N.
    • Journal Title

      Cancer Research

      Volume: 70 Pages: 9381-9390

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22019042
  • [Journal Article] Real-time in vivo imaging of p16^<Ink4a> gene expression : a new approach to study senescence stress signaling in living animals2010

    • Author(s)
      Ohtani N, Yamakoshi K, Takahashi A, Hara E.
    • Journal Title

      Cell Division 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] Cellular senescence : Its role in tumor suppression and aging.2009

    • Author(s)
      Ohtani N, Mann D. J., Hara E.
    • Journal Title

      Cancer Science 100

      Pages: 792-797

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] Real-time in vivo imaging of p16^<Ink4a> reveals cross talk with p53.2009

    • Author(s)
      Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, J. Mann D. J, Ohmura M., Hirao A, Saya H, Arase S, Hayashi Y, Nakao K., Matsumoto M, Ohtani N, Hara E
    • Journal Title

      J.Cell Biol. 186

      Pages: 393-407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] Real-time in vivo imaging of p16^<Ink4a> reveals cross talk with p532009

    • Author(s)
      Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, J.Mann D.J, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E
    • Journal Title

      Journal of Cell Biology 186

      Pages: 393-407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20058027
  • [Journal Article] Real-time in vivo imaging of p16^<Ink4a> reveals cross talk with p532009

    • Author(s)
      Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, J.Mann D.J, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E
    • Journal Title

      Journal of Cell Biology 186

      Pages: 393-407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] Cellular senescence: Its role in tumor suppression and aging.2009

    • Author(s)
      Naoko Ohtani, David J. Mann, and Eiji Hara
    • Journal Title

      Cancer Science 100

      Pages: 792-797

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20058027
  • [Journal Article] Cellular senescence : Its role in tumor suppression and aging2009

    • Author(s)
      Naoko Ohtani, et al.
    • Journal Title

      Cancer Science 100

      Pages: 792-797

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] CDKインヒビターp21^<Waf1/Cip1>遺伝子発現ダイナミクスの生体内イメージング 生命現象の動的理解を目指すライブイメージング2008

    • Author(s)
      大谷直子、原英二
    • Journal Title

      実験医学 増刊号 vol.26,No.17

      Pages: 50-58

    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] 生体内におけるp21遺伝子発現のリアルタイム・イメージング2008

    • Author(s)
      大谷直子、原英二
    • Journal Title

      細胞工学 vol27,No.2

      Pages: 170-171

    • Data Source
      KAKENHI-PROJECT-20300229
  • [Journal Article] Epigenetic abnormalities in cutaneous squamous cell carcinomas : Frequent inactivation of the RBI/p16 and p53 pathways.2006

    • Author(s)
      Murao, K., Kubo, Y., Ohtani, N., Hara, E., Arase S
    • Journal Title

      British Journal of Dermatology 155

      Pages: 999-1005

    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] and Arase S Epigenetic abnormalities in cutaneous squamous cell carcinomas : Frequent inactivation of the RB1/p16 and p53 pathways.2006

    • Author(s)
      Murao, K., Kubo, Y., Ohtani, N., Hara, E.
    • Journal Title

      British Journal of Dermatology 155

      Pages: 999-1005

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Mitogenic signalling and the p16INK4a/Rb pathway co-operate to enforce irreversible cellular senescence2006

    • Author(s)
      Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
    • Journal Title

      Nature Cell Biology 8

      Pages: 1291-1297

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Mitogenic signalling and the p16INK4a/Rb pathway co-operate to enforce irreversible cellular senescence.2006

    • Author(s)
      Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
    • Journal Title

      Nature Cell Biology 8

      Pages: 1291-1297

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Mitogenic signalling and the p16INK4a/Rb pathway co-operate to enforce irreversible cellular senescence.2006

    • Author(s)
      Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., H., Saya, H., Hara, E.
    • Journal Title

      Nature Cell Biology 8

      Pages: 1291-1297

    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Epigenetic abnormalities in cutaneous squamous cell carcinomas : Frequent inactivation of the RB1/p16 and p53 pathways.2006

    • Author(s)
      Murao, K., Kubo, Y., Ohtani, N., Hara, E., Arase S
    • Journal Title

      British Journal of Dermatology 155

      Pages: 999-1005

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53.2005

    • Author(s)
      Maehara K, Yamakoshi K, Ohtani N, Kubo Y, Takahashi A, Arase S, Jones N, Hara E
    • Journal Title

      Journal of Cell Biology 168

      Pages: 552-560

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Presentation] Obesity-induced gut microbiome and liver cancer ~ The suppression mechanism of anti-tumor immunity ~2019

    • Author(s)
      Naoko Ohtani
    • Organizer
      U.S.-Japan Cooperative Medical Sciences Program Cancer Panel Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Regular exercise suppresses obesity-associated HCC development2019

    • Author(s)
      Naoki Takada, Miho Kumagai, Tatsuya Ando, Fumitaka Kamachi, and Naoko Ohtani
    • Organizer
      the 9th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Obesity-induced gut microbiome and liver cancer2019

    • Author(s)
      Naoko Ohtani
    • Organizer
      21st International Conference on Emerging Infectious Diseases in the Pacific Rim
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 肥満関連腸内細菌による肝がんの進展機構~がん微小環境の変化に着目して~2018

    • Author(s)
      大谷直子
    • Organizer
      千葉大学リーディング研究育成プログラム 第3回免疫希少・難治性疾患に対する革新的治療創生研究シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] The role of gut microbial metabolites in obesity-associated liver cancer development via gut liver axis2018

    • Author(s)
      Naoko Ohtani, Tze Mun Loo, Fumitaka Kamachi
    • Organizer
      第41回 日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 腸内細菌を指標とした大腸癌診断キットの開発研究2018

    • Author(s)
      奥村 慎太郎, 長山 聡, 大谷 直子, 坂井 義治, 原 英二
    • Organizer
      第77回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] The Role of SASP and Anti-tumor Immunity in Tumor-microenvironment of Obesity-associated liver cancer2018

    • Author(s)
      Naoko Ohtani
    • Organizer
      Australia Japan Medical Research Symposium September 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Toll-like Receptor及びDNAセンサーを介した肥満誘導性肝癌の発症2018

    • Author(s)
      羅 智文, 岡田 遼, 原 英二, 大谷 直子, 高橋 暁子
    • Organizer
      第77回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 門亢症の包括的マネジメント 当院におけるリファキシミンの初期使用成績 腸内細菌叢の変化を踏まえて2018

    • Author(s)
      湯川 芳美, 大谷 直子, 河田 則文
    • Organizer
      日本門脈圧亢進症学会
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] The role and the mechanism of SASP in tumor micro-environment of obesity-associated liver cancer2018

    • Author(s)
      Naoko Ohtani
    • Organizer
      The 37th Sapporo International Cancer Symposium -Deciphering the complexity of cancer microenvironment-
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] The Role of SASP and Anti-tumor Immunity in Tumor-microenvironment of Obesity-associated liver cancer2018

    • Author(s)
      Naoko Ohtani
    • Organizer
      The 45th Naito Conference Immunological and Molecular Bases for Cancer Immunotherapy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Gut-Liver axis~腸内細菌代謝物による肝癌の進展機構~2017

    • Author(s)
      大谷直子
    • Organizer
      第27回日本病態生理学会大会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Obesity-associated gut microbiota and cancer development2017

    • Author(s)
      Naoko Ohtani, Tze Mun Loo, Fumitaka Kamachi
    • Organizer
      The 76th Annual meeting of JCA  Symposium 8
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] がん微小環境の細胞老化随伴分泌現象による肥満誘導性肝がんの促進機構2017

    • Author(s)
      大谷直子
    • Organizer
      第38回日本炎症・再生医学会 シンポジウム3 炎症と老化
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Gut Microbiota Promotes Obesity-associated Liver Cancer through PGE2 mediated Suppression of Antitumor Immunity2017

    • Author(s)
      Naoko Ohtani
    • Organizer
      International Symposium on Imaging Frontier (ISIF2017)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 腸内細菌由来リガンドとTLRシグナルによるPGE2の生成と肝癌の進展2017

    • Author(s)
      大谷直子
    • Organizer
      第11回メタボロームシンポジウム セッション 医薬分野
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] The Role of SASP in Tumor Microenvironment of Obesity-associated Liver Cancer2017

    • Author(s)
      Naoko Ohtani
    • Organizer
      The 48th International Symposium of The Princess Takamatsu Cancer Research Fund
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 腸内細菌叢が肥満誘導性肝癌の進展を促進する:デオキシコール酸(DCA)とリポタイコ酸(LTA)の協調作用2017

    • Author(s)
      羅 智文、蒲池 史卓、渡辺 喜洋、神田  浩明、大島  正伸、岩間  厚志、有田 誠、原 英二、大谷 直子
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] IL-33 from senescent HSCs promotes obesity-associated liver cancer development by suppression of anti-tumor immunity2017

    • Author(s)
      Fumitaka Kamachi, Masaru Nakamura, Shota Ymazaki, Susumu Nakae, Eiji Hara & Naoko Ohtani
    • Organizer
      19th International Symposium on Cells of the Hepatic Sinusoid (ISCHS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 腸内細菌によるリノール酸代謝産物の免疫系への作用2017

    • Author(s)
      新井 達也、蒲池 史卓、有田 誠、岸野 重信、小川 順、大谷 直子
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 腸内細菌代謝産物が形成する肝癌微小環境におけるinterleukin-33の役割解明2017

    • Author(s)
      蒲池 史卓、中村 大、山﨑 翔太、中島 将博、羅 智文、吉本 真、新井 達也、原田 陽介、久保 允人、田口 速男、中江 進、原 英二、大谷 直子
    • Organizer
      第1回消化器臓器間ネットワーク研究会
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] IL-33/ST2 pathway promotes obesity-associated liver cancer development2017

    • Author(s)
      Fumitaka Kamachi, Masaru Nakamura, Shota Yamazaki, Tze Mun Loo, Shin Yoshimoto, Tatsuya Arai, Yohsuke Harada, Masato Kubo, Susumu Nakae, Eiji Hara, Naoko Ohtani
    • Organizer
      The 19h Takeda Science Foundation Symposium on Biosciences
    • Place of Presentation
      Suita, Osaka, Japan
    • Year and Date
      2017-01-20
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] SASP因子の相乗効果による肥満誘導性肝がん形成促進機構の解明2017

    • Author(s)
      山崎 翔太、蒲池 史卓、中村 大、中島 将博、Loo Mun、吉本 真、新井 達也、田口 速男、中江 進、原 英二、大谷 直子
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Effects of gut microbial metabolites of linoleic acid on cytokine production by immune cells2017

    • Author(s)
      Fumitaka Kamachi, Tatsuya Arai, Makoto, Arita, Naoko Ohtani
    • Organizer
      第46回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 細胞老化・SASP:その誘導機構と生体における役割2017

    • Author(s)
      大谷直子
    • Organizer
      第44回日本毒性学会学術年会 シンポジウム7 ストレスバイオロジーから分子毒性学への展開
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 肝臓オルガノイドを用いた肥満誘導性肝臓がん発症モデルの構築及び、がんの起源細胞の解明2017

    • Author(s)
      窪田 達寛、安藤 達也、福井 優也、渡辺 喜洋、小澤 崇之、蒲池 史卓、八尾 良司、佐藤 俊朗、大谷 直子
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 細胞老化の生体における役割~腸内細菌代謝物による肝星細胞の老化~2017

    • Author(s)
      大谷直子
    • Organizer
      脳血管抗加齢研究会 特別講演2
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Gut Microbiota Promotes Obesity-associated Liver Cancer through PGE2 mediated Suppression of Antitumor Immunity2017

    • Author(s)
      Naoko Ohtani
    • Organizer
      KEYSTONE SYMPOSIA Aging and Mechanism of Aging-related Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Gut Microbiota Promotes Obesity-associated Liver Cancer Development: a collaborative role of lipoteichoic acid and deoxycholic acid2017

    • Author(s)
      Naoko Ohtani
    • Organizer
      The 4th JSGE International Topic Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 腸肝軸と肝がん~腸内細菌代謝物デオキシコール酸による肝がんの進展機構~2017

    • Author(s)
      大谷直子
    • Organizer
      第39回胆汁酸研究会 シンポジウム 胆汁酸代謝と腸内細菌
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] TLRシグナルによる脂質代謝物の生成と肝がんの促進2017

    • Author(s)
      大谷直子
    • Organizer
      第5回がんと代謝研究会 in 札幌 セッション4 腸内細菌と代謝
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Synergism of SASP factors: activation mechanism of interleukin-33 in senescent hepatic stellate cells in promoting obesity-associated liver cancer2017

    • Author(s)
      Shota Yamazaki, Fumitaka Kamachi, Masaru Nakamura, Masahiro Nakajima, Tze Mun Loo, Shin Yoshimoto, Tatsuya Arai, Hayao Taguchi, Susumu Nakae, Eiji Hara, Naoko Ohtani
    • Organizer
      The 19h Takeda Science Foundation Symposium on Biosciences
    • Place of Presentation
      Suita, Osaka, Japan
    • Year and Date
      2017-01-20
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 肥満により増加する腸内細菌による肝がん進展メカニズム2016

    • Author(s)
      大谷直子
    • Organizer
      第16回抗加齢医学会総会シンポジウム 腸内フローラの臨床への展開
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-06-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] The Mechanism of Obesity-associated Liver Carcinogenesis: a co-operation between gut microbial metabolites and lipid.2016

    • Author(s)
      Naoko Ohtani
    • Organizer
      EASL, European association for the study of the liver, The International Liver Congress 2016
    • Place of Presentation
      Fira Barcelona Gran Via (Barcelona, Spain)
    • Year and Date
      2016-04-14
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] p16INK4aによる個体老化の新たなメカニズム2016

    • Author(s)
      大谷直子
    • Organizer
      第89回日本生化学会大会 シンポジウム 加齢にともなう幹細胞変化と疾患の分子基盤
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 細胞老化・SASPとその生体における役割2016

    • Author(s)
      大谷直子
    • Organizer
      日本放射線影響学会 第59回大会 シンポジウム 低線量放射線生物影響の課題への分子生物学的アプローチ
    • Place of Presentation
      JMSアステールプラザ(広島県・広島市)
    • Year and Date
      2016-10-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] Cooperative role of gut microbial components and metabolites in obesity-associated liver cancer development.2016

    • Author(s)
      Tze Mun Loo and Naoko Ohtani
    • Organizer
      The 75th Annual Meeting of the Japanese Cancer Association Symposium 10(日本癌学会), Therapeutic vulnerability in infection/inflammation-associated cancer
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-10-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] p16INK4aによる個体老化の新たなメカニズム2016

    • Author(s)
      大谷直子
    • Organizer
      第89回日本生化学会大会 シンポジウム 加齢にともなう幹細胞変化と疾患の分子基盤
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] 細胞老化・SASPとその生体における役割2016

    • Author(s)
      大谷直子
    • Organizer
      日本放射線影響学会 第59回大会 シンポジウム 低線量放射線生物影響の課題への分子生物学的アプローチ
    • Place of Presentation
      JMSアステールプラザ(広島県広島市)
    • Year and Date
      2016-10-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] The role of gut microbiota for obesity-induced liver cancer development.2016

    • Author(s)
      Naoko Ohtani
    • Organizer
      RIKEN IMS-JSI International Symposium on Immunology 2016, Immune homeostasis and diseases.
    • Place of Presentation
      Pasifico Yokohama(Yokohama, Kanagawa Japan)
    • Year and Date
      2016-06-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] The role of gut microbiota for obesity-induced liver cancer development.2016

    • Author(s)
      Naoko Ohtani
    • Organizer
      RIKEN IMS-JSI International Symposium on Immunology 2016, Immune homeostasis and diseases.
    • Place of Presentation
      Pacifico Yokohama(Yokohama, Kanagawa Japan)
    • Year and Date
      2016-06-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 肥満誘導性の腸内細菌代謝物による肝星細胞の細胞老化・SASPと肝がんの促進2016

    • Author(s)
      羅 智文、蒲池史卓、渡辺喜洋、大谷直子
    • Organizer
      第39回日本分子生物学会年会 シンポジウム 臓器老化による臓器間ネットワークの破綻を探る
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-12-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] 肥満により増加する腸内細菌による肝がん進展メカニズム2016

    • Author(s)
      大谷直子
    • Organizer
      第16回抗加齢医学会総会シンポジウム 腸内フローラの臨床への展開
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-06-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 肥満誘導性の腸内細菌代謝物による肝星細胞の細胞老化・SASPと肝がんの促進2016

    • Author(s)
      羅 智文、蒲池史卓、渡辺喜洋、大谷直子
    • Organizer
      第39回日本分子生物学会年会 シンポジウム 臓器老化による臓器間ネットワークの破綻を探る
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-12-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] The role of gut microbiota for obesity-associated liver cancer progression.2016

    • Author(s)
      Naoko Ohtani
    • Organizer
      International Symposium of the Center for Animal Disease Models 2016 -Metabolic disease and Aging- Tokyo, Japan
    • Place of Presentation
      Tokyo Garden Palace(Tokyo Japan)
    • Year and Date
      2016-07-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] 肥満誘導性肝臓癌におけるinterleukin-33の役割解明2016

    • Author(s)
      中村 大、蒲池 史卓、山崎 翔太、新井 達也、原田 陽介、久保 允人、羅 智文、吉本 真、中江 進、原 英二、大谷 直子
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] IL-33 promotes obesity-associated liver cancer development2016

    • Author(s)
      Fumitaka Kamachi, Shota Yamazaki, Tatsuya Arai, Yohsuke Harada, Masato Kubo, Susumu Nakae, and Naoko Ohtani
    • Organizer
      第45回日本免疫学会学術集会The 45th Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      沖縄コンベンションセンター、(沖縄県宜野湾市)
    • Year and Date
      2016-12-06
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] The mechanism of obesity-induced liver cancer development through gut microbial components and metabolites.2016

    • Author(s)
      Naoko Ohtani
    • Organizer
      Bridging Biomedical Worlds meeting, Frontiers in Human Microbiota Symbiotic Interactions
    • Place of Presentation
      University of Hong Kong (Hong Kong, China)
    • Year and Date
      2016-05-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] The role of gut microbiota for obesity-associated liver cancer progression.2016

    • Author(s)
      Naoko Ohtani
    • Organizer
      Tokyo University of Science, International Symposium of the Center for Animal Disease Models 2016 -Metabolic disease and Aging-.
    • Place of Presentation
      Tokyo Garden Palace(Tokyo Japan)
    • Year and Date
      2016-07-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] 規則的な運動は肥満誘導性肝腫瘍の発症を抑制する2016

    • Author(s)
      熊谷 実保、蒲池 史卓、安藤 達也、新井 友里子、井手口 真理、中村 大、小澤 崇之、渡辺 喜洋、山埼 翔太、羅 智文、大谷 直子
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-16H04699
  • [Presentation] Cooperative role of gut microbial components and metabolites in obesity-associated liver cancer development.2016

    • Author(s)
      Tze Mun Loo and Naoko Ohtani
    • Organizer
      The 75th Annual Meeting of the Japanese Cancer Association Symposium 10(日本癌学会), Therapeutic vulnerability in infection/inflammation-associated cancer
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-10-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] The mechanism of obesity-induced liver cancer development through gut microbial components and metabolites.2016

    • Author(s)
      Naoko Ohtani
    • Organizer
      Bridging Biomedical Worlds meeting, Frontiers in Human Microbiota Symbiotic Interactions
    • Place of Presentation
      University of Hong Kong (Hong Kong, China)
    • Year and Date
      2016-05-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] The Mechanism of Obesity-associated Liver Carcinogenesis: a co-operation between gut microbial metabolites and lipid.2016

    • Author(s)
      Naoko Ohtani
    • Organizer
      EASL, European association for the study of the liver, The International Liver Congress 2016
    • Place of Presentation
      Fira Barcelona Gran Via (Barcelona, Spain)
    • Year and Date
      2016-04-14
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] 肥満による肝がん促進機構 ~腸内細菌代謝物の関与~2015

    • Author(s)
      大谷直子
    • Organizer
      第18回 日本臨床腸内微生物学会総会・学術集会 教育講演 III 病態と治療法を探る
    • Place of Presentation
      日本医科大学附属病院橘桜会館(東京都)
    • Year and Date
      2015-08-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] Gut microbiota and obesity-associated hepatocarcinogenesis, The 74th Annual meeting of The JCA2015

    • Author(s)
      Naoko Ohtani
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2015-10-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] Obesity-induced gut microbial metabolite promotes liver cancer through senencnce-associated secretome2015

    • Author(s)
      Naoko Ohtani
    • Organizer
      24th Symposium on Intestinal Flora, Dynamism of Intestinal microbiota - pathophysiology of microbial metabolites
    • Place of Presentation
      ヤクルトホール(東京都)
    • Year and Date
      2015-10-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] 腸内細菌代謝産物による細胞老化の誘導と肝がん2015

    • Author(s)
      大谷直子
    • Organizer
      第11回 日本食品免疫学会学術大会、シンポジウム3 「老化と腸内環境、腸管機能」
    • Place of Presentation
      伊藤謝恩ホール(東京都)
    • Year and Date
      2015-10-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] 肥満により増加する腸内細菌による肝がん促進機構2015

    • Author(s)
      大谷直子、羅 智文
    • Organizer
      第36回 日本肥満学会 シンポジウム「肥満と臓器障害」
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2015-10-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12709
  • [Presentation] 細胞老化・SASPによる発がん-肥満により増加する腸内細菌の代謝産物DCAは肝がんを促進する-2014

    • Author(s)
      大谷直子
    • Organizer
      第23回日本小児胆汁酸研究会
    • Year and Date
      2014-02-15
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] 肥満に伴い増加する腸内細菌の代謝産物デオキシコール酸によるSASPを介した肝がん促進作用2014

    • Author(s)
      大谷直子, 吉本 真, 羅 智文, 原 英二
    • Organizer
      第47回日本無菌生物ノートバイオロジー学会総会 シンポジウム
    • Year and Date
      2014-01-31
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] 細胞老化による炎症とがん -肥満に伴い増加する腸内細菌の代謝産物による肝がん促進作用-2013

    • Author(s)
      大谷直子, 吉本 真, 羅 智文, 原 英二
    • Organizer
      第36回日本分子生物学会年会 ワークショップ 「生老病死」の分子生物学の最前線
    • Year and Date
      2013-12-03
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] The role of cellular senescence in obesity-associated hepatic carcinogenesis2013

    • Author(s)
      Ohtani N, Hara E
    • Organizer
      第72回日本癌学会総会 シンポジウム Animal models in cancer research
    • Year and Date
      2013-10-05
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] 細胞老化の二面性 -がん抑制機構SASP-2013

    • Author(s)
      大谷直子
    • Organizer
      第65回日本細胞生物学会大会 シンポジウム 老化の分子機構
    • Year and Date
      2013-06-21
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] 肥満により増加する腸内細菌の代謝産物DCAは肝癌発症を促進する2013

    • Author(s)
      大谷直子
    • Organizer
      第1回がんと代謝研究会
    • Year and Date
      2013-10-30
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] 細胞老化による炎症とがん-肥満により増加する腸内細菌の代謝産物が肝がんを促進する-2013

    • Author(s)
      大谷直子
    • Organizer
      第45回北陸実験動物研究会
    • Year and Date
      2013-09-14
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] 肥満により増加する腸内細菌の代謝産物が肝がんを促進する2013

    • Author(s)
      大谷直子
    • Organizer
      第41回臨床免疫学会総会 シンポジウム
    • Year and Date
      2013-11-28
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Senescence-associated inflammatory secretome and cancer development2013

    • Author(s)
      Naoko Ohtani
    • Organizer
      JST-CREST International Symposium "Frontiers in Immunology and Inflammation"
    • Year and Date
      2013-02-13
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Obesity-induced gut microbial metabolite promotes liver cancer via senescence secretome2013

    • Author(s)
      Naoko Ohtani, Shin Yoshimoto, Tze Mun Loo, Hiroaki Kanda, Seidai Sato, Yuichi Ishikawa and Eiji Hara
    • Organizer
      Welcome Trust scientific conference. Cell Senescence in Cancer and Aging
    • Year and Date
      2013-07-22
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Cellular senescence-associated inflammation and cancer2012

    • Author(s)
      Naoko Ohtani
    • Organizer
      2nd Japanese-French Cancer Workshop
    • Year and Date
      2012-11-29
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Senescence-Associated Secretory Phenotypes (SASPs) Promote Obesity Associated Hepatocarcinogenesis2012

    • Author(s)
      Naoko Ohtani
    • Organizer
      Keystone Symposia "Aging and Dideases of Aging"
    • Year and Date
      2012-10-25
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Senescence-associated secretory phenotype (SASP) in fatty-liver based hepatic cancer2011

    • Author(s)
      Naoko Ohtani, Shin Yoshimoto, Eiji Hara
    • Organizer
      第34回日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Senescence-associated secretory phenotype (SASP) in fatty-liver based hepatic cancer2011

    • Author(s)
      Naoko Ohtani, Shin Yoshimoto, Eiji Hara
    • Organizer
      第34回日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PUBLICLY-22019042
  • [Presentation] Intrinsic cooperation between p16^<Ink4a> and p21^<Waf/Cip1> in the onset of cellular senescence and tumor suppression in vivo.2010

    • Author(s)
      Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Ishikawa Y, Sone S, Hara E., Ohtani N.
    • Organizer
      Cold Spring Harbor Laboratory Meeting, Molecular Genetics of Aging
    • Place of Presentation
      Cold Spring Harbor, NewYork, USA
    • Year and Date
      2010-09-29
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Presentation] Identification of tumor stimulating factors in cellular senescence.2010

    • Author(s)
      Imai Y, Takahashi A, Yao R, Ohtani N, HirotaT, Tahara H, Ide T, Noda T, Hara E
    • Organizer
      日本癌学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Presentation] Intrinsic cooperation between p16^<Ink4a> and p21^<Waf/Cip1> in the onset of cellular senescence and tumor suppression in vivo.2010

    • Author(s)
      Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Ishikawa Y, Sone S, Hara E., Ohtani N
    • Organizer
      Cold Spring Harbor Laboratory Meeting, Molecular Genetics of Aging Cold Spring Harbor
    • Place of Presentation
      New York, USA
    • Year and Date
      2010-09-29
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Presentation] Intrinsic cooperation between p16^<Ink4a> and p21^<Waf/Cip1> in the onset of cellular senescence and tumor suppression in vivo.2010

    • Author(s)
      Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Ishikawa Y, Sone S, Hara E., Ohtani N.
    • Organizer
      Cold Spring Harbor Laboratory Meeting, Molecular Genetics of Aging
    • Place of Presentation
      Cold Spring Harbor, New York, USA
    • Year and Date
      2010-09-29
    • Data Source
      KAKENHI-PUBLICLY-22019042
  • [Presentation] Visualizing the dynamics of Oncogenic stress response in living mice.2009

    • Author(s)
      Naoko Ohtani
    • Organizer
      American Association for cancer Research (AACR) special conference in Cancer Research: Mouse Models of Cancer
    • Place of Presentation
      米国 サンフランシスコ Hyatt Regency
    • Year and Date
      2009-01-13
    • Data Source
      KAKENHI-PROJECT-20058027
  • [Presentation] Real-time in vivo imaging of oncogenic stress response in living animals.2009

    • Author(s)
      大谷直子
    • Organizer
      Cell Proliferation Control International Symposium CELL CYCLE and CELL ARCHITECTURE
    • Place of Presentation
      Nagoya(招待講演)
    • Year and Date
      2009-02-28
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Presentation] Cooperative role of p21^<Waf1/Cip1> and p16^<INK4a> in skin cancer prevention in mice2009

    • Author(s)
      Takeuchi S, Takahashi A, Motoi N, Yamakoshi K, Ishikawa Y, Sone S, Hara E, Ohtani N
    • Organizer
      日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Presentation] Real-time in vivo imaging of p16^<INK4a> expression unveils a cross-talk between p53 and p16^<INK4a>2009

    • Author(s)
      Yamakoshi K, Takahashi A, Ohtani N, Hara E
    • Organizer
      Salk Institute, Mechanism & Models of Cancer meeting
    • Place of Presentation
      La Jolla, U.S.A.
    • Year and Date
      2009-08-14
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Presentation] 癌抑制機構としての細胞老化2009

    • Author(s)
      大谷直子
    • Organizer
      日本再生医療学会シンポジウム、ステムセルエイジング
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2009-03-05
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Presentation] Visualizing the dynamics of Oncogenic stress response in living mice2009

    • Author(s)
      Naoko Ohtani
    • Organizer
      American Association for cancer Research (AACR) special conference in Cancer Research : Mouse Models of Cancer
    • Place of Presentation
      米国サンフランンシスコ Hyatt Regency
    • Year and Date
      2009-01-13
    • Data Source
      KAKENHI-PROJECT-20300229
  • [Presentation] The role of cellular senescence in obesity-associated hepatic carcinogenesis

    • Author(s)
      Naoko Ohtani and Eiji Hara
    • Organizer
      第72回日本癌学会総会シンポジウム
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Senescence-Associated Secretory Phenotypes(SASPs) Promote Obesity Associated Hepatocarcinogenesis

    • Author(s)
      Naoko Ohtani
    • Organizer
      Keystone Symposia〝Aging and Dideases of Aging″
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] 肥満により増加する腸内細菌の代謝産物DCAは肝がん発症を促進する

    • Author(s)
      大谷直子
    • Organizer
      第1回がんと代謝研究会 特別講演
    • Place of Presentation
      鶴岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Induction of cellular senescence in obesity-associated hepatic carcinogenesis

    • Author(s)
      Shin Yoshimoto, Tze Mun Loo, Hiroaki Kanda, Seidai Sato, Yuichi Ishikawa, Eiji Hara & Naoko Ohtani
    • Organizer
      Keystone Symposia〝The Role of Inflammation during Carcinogenesis″
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Cellular senescence-associated inflammation and cancer

    • Author(s)
      Naoko Ohtani
    • Organizer
      2nd Japanese-French Cancer Workshop
    • Place of Presentation
      Naruto, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] 細胞老化による炎症とがん-肥満に伴い増加する腸内細菌の代謝産物による肝がん促進作用-

    • Author(s)
      大谷直子
    • Organizer
      第36回分子生物学会年会 ワークショップ
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] Senescence-associated inflammatory secretome and cancer development

    • Author(s)
      Naoko Ohtani
    • Organizer
      JST-CREST International Symposium 〝Frontiers in Immunology and Inflammation″
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300343
  • [Presentation] 肥満により増加する腸内細菌の代謝産物が肝がんを促進する

    • Author(s)
      大谷直子
    • Organizer
      第41回日本臨床免疫学会総会シンポジウム
    • Place of Presentation
      下関
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300343
  • 1.  KUBO Yoshiaki (10260069)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  HIDA Yasutoshi (90380039)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  HARA Eiji (80263268)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 4.  TAKUBO Keiyo (50502788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  ROKUTAN Kazuhito (10230898)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  酒井 敏行 (20186993)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  村尾 和俊 (40363171)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  蒲池 史卓 (00747800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 19 results
  • 9.  福尾 惠介 (40156758)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  安田 修 (00372615)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  西川 浩樹 (30769609)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  榎本 平之 (40449880)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  横路 三有紀 (80757188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  中台 枝里子 (40453790)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  山口 良弘 (00737009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  和田 崇之 (70332450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  IMAI Akiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 18.  Iwamoto Masashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  KOGA Tomoaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  OSHIMA Masanobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  OZAWA Manabu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  ABE Manabu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  KAMISUKI Shinji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  MIYATA kenichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  OKADA ryo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 26.  LOO tze mun
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  WATANABE Sugiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  Tsukuda Senko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 29.  Ohashi Hirofumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  KONDO Eisaku
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  平尾 敦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  鈴木 信弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  岩見 真吾
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  渡士 幸一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 35.  相崎 英樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 36.  石井 孝司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  朴 三用
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  有田 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  有田 正規
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  杉本 幸彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  中村 卓郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  井本 正哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  神田 浩明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  成宮 周
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  脇田 隆字
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  池本 円
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  脇田 将裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  河田 則文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  近藤 恭光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  瀧川 奈義夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  市原 英基
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 52.  木浦 勝行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 53.  桑原 一彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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