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HIROMURA MUNENORI  広村 宗範

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… Alternative Names

広村 宗範  ヒロムラ ムネノリ

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Researcher Number 00773186
Other IDs
Affiliation (Current) 2025: 昭和大学, 医学部, 兼任講師
Affiliation (based on the past Project Information) *help 2023: 昭和大学, 医学部, 兼任講師
2020 – 2022: 昭和大学, 医学部, 講師
Review Section/Research Field
Except Principal Investigator
Basic Section 47040:Pharmacology-related / Basic Section 42040:Laboratory animal science-related
Keywords
Except Principal Investigator
アプタマー / 終末糖化産物 / AGE / 動脈硬化 / マウス / 糖尿病 / RAGE / 男性不妊症 / マウスモデル / DNAアプタマー … More / 男性不妊 / RAGEアプタマー / マクロファージ / atherosclerosis / macrophage / aptamer / AGEs / 心肥大 Less
  • Research Projects

    (3 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (3 People)
  •  Effects of AGE-inhibitory DNA aptamer on male infertility

    • Principal Investigator
      Mori Yusaku
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Showa University
  •  Evaluation of DNA aptamer raised against advanced glycation end products on comprehensive prevention of aging-related disorders

    • Principal Investigator
      Yamagishi Shoichi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Showa University
  •  Effects of DNA-aptamer raised against AGEs on atherosclerosis in ApoE-null mice

    • Principal Investigator
      Terasaki Michishige
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Showa University

All 2022 2020

All Journal Article Presentation

  • [Journal Article] ①AGE-RAGE axis stimulates oxidized LDL uptake into macrophages through cyclin-dependent kinase 5-CD36 pathway via oxidative stress generation2020

    • Author(s)
      Yashima H, Terasaki M, Sotokawauchi A, Matsui T, Mori Y, Saito T, Osaka N, Kushima H, Hiromura M, Ohara M, Fukui T, Yamagishi S-i.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 23 Pages: 9263-9263

    • DOI

      10.3390/ijms21239263

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07075
  • [Journal Article] A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression2020

    • Author(s)
      Terasaki M, Yashima H, Mori Y, Saito T, Matsui T, Hiromura M, Kushima H, Osaka N, Ohara M, Fukui T, Hirano T, Yamagishi SI.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 13 Pages: 4811-4811

    • DOI

      10.3390/ijms21134811

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07075
  • [Presentation] DNA-aptamer raised against receptor for advanced glycaion end products inhibits atherosclerosis.2022

    • Author(s)
      Terasaki M, Mori Y, Yashima H, Saito T, Sotokawauchi A, Matsui T, Hiromura M, Osaka N, Kawakami R, Shiraga Y, Ohara M, Fukui T, Yamagishi SI.
    • Organizer
      The 29th Scientific Meeting of the International Society of Hypertension.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] DNA-aptamer raised against receptor for advanced glycation end products inhibits atherosclerosis2022

    • Author(s)
      Terasaki M, Mori Y, Yashima H, Saito T, Sotokawauchi A, Matsui T, Hiromura M, Osaka N, Kawakami R, Shiraga Y, Ohara M, Fukui T, Yamagishi SI.
    • Organizer
      第29回国際高血圧学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07075
  • [Presentation] 終末糖化産物受容体(RAGE)阻害アプタマーは動脈硬化進展を抑制する.2022

    • Author(s)
      寺崎 道重, 森 雄作, 八島 広典, 松井 孝憲, 斎藤 智美, 大坂 直也, 広村 宗範, 高畑 洋, 藤川大輝, 川上 来知, 白神 佳枝, 外川内 亜美, 小原 信, 福井 智康, 山岸 昌一.
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] 終末糖化産物受容体(RAGE)に対するDNAアプタマーは動脈硬化進展を抑制する~動脈硬化モデルマウスによる検討~.2022

    • Author(s)
      寺﨑 道重, 森 雄作, 八島 広典, 外川内 亜美, 松井 孝憲, 斎藤 智美, 広村 宗範, 大坂 直也, 藤川 大輝, 川上 来知, 白神 佳枝, 小原 信, 福井 智康, 山岸 昌一.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] 終末糖化産物受容体(RAGE)阻害アプタマーは動脈硬化進展を抑制する2022

    • Author(s)
      寺崎 道重、森 雄作、八島 広典、松井 孝憲、斎藤 智美、大坂 直也、広村 宗範、高畑 洋、藤川 大輝、川上 来知、白神 佳枝、外川内 亜美、小原 信、福井 智康、山岸 昌一
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K07075
  • 1.  Yamagishi Shoichi (40281026)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 2.  Mori Yusaku (90595919)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  Terasaki Michishige (90621342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

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