NISHIKAWA Masashi 西川将司

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Nishikawa Masashi 西川将司

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Researcher Number	00871758
Other IDs	https://orcid.org/0000-0003-2542-8057
Affiliation (Current)	2026: 名古屋大学, 理学研究科, 助教
Affiliation (based on the past Project Information) *help	2026: 名古屋大学, 理学研究科, 助教 2022 – 2024: 名古屋大学, 理学研究科, 助教 2020 – 2021: 愛知県医療療育総合センター発達障害研究所, 分子病態研究部, リサーチレジデント
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / 0902:General internal medicine and related fields
Keywords	Principal Investigator 知的障害 / Gタンパク質 / シグナル伝達 / 細胞骨格 / 発達障害 / 神経発達 / アクチン細胞骨格 / Rhoファミリー / Rho / G蛋白質 … More / 細胞内シグナル伝達 / Cdc42 / 神経発生 / Rho GTPase / Rac / 子宮内胎仔脳遺伝子導入 / 神経細胞移動 / アクチン / 大脳皮質構築 / PAK1 / Rac3 / 子宮内胎児脳電気穿孔法 / 小頭症 / 知的障害(ID) / 発現解析 / マウス組織 / 神経細胞発達 / RhoGEF Less

小児知的障害の遺伝子変異から読み解く神経発生におけるRHOGの役割と病態機序Principal Investigator
- Principal Investigator
  
  西川将司
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya University
Underlying pathomechanisms of Cdc42 variants in microcephaly and cortical malformation with intellectual disabilityPrincipal Investigator
- Principal Investigator
  
  Nishikawa Masashi
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya University
Physiological functions and pathogenic mechanisms of Rac3, an intellectual disability-associated G protein, in cerebral developmentPrincipal Investigator
- Principal Investigator
  
  Nishikawa Masashi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya University
  Institute for Developmental Research Aichi Developmental Disability Center
Pathophysiological analyses of PLEKHG2, a responsible gene for neurodevelopmental disorders, during corticogenesisPrincipal Investigator
- Principal Investigator
  
  Nishikawa Masashi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0902:General internal medicine and related fields
- Research Institution
  Institute for Developmental Research Aichi Developmental Disability Center

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Live Imaging of Migrating Neurons and Glial Progenitors Visualized by in Utero Electroporation2024
- Author(s)
  Nishikawa Masashi、Nagata Koh-ichi、Tabata Hidenori
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: - Pages: 201-209
- DOI
  10.1007/978-1-0716-3810-1_17
- ISBN
  9781071638095, 9781071638101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14946, KAKENHI-PROJECT-21K07309
[Journal Article] A Novel Constitutively Active c.98G>C, p.(R33P) Variant in RAB11A Associated with Intellectual Disability Promotes Neuritogenesis and Affects Oligodendroglial Arborization2023
- Author(s)
  Yumi Tsuneura, Taeko Kawai, Keitaro Yamada, Shintaro Aoki, Mitsuko Nakashima, Shima Eda, Tohru Matsuki, Masashi Nishikawa, Koh-ichi Nagata, Yasushi Enokido, Hirotomo Saitsu, Atsuo Nakayama
- Journal Title
  
  Human Mutation
  
  Volume: 2023 Pages: 8126544-8126544
- DOI
  10.1155/2023/8126544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15912, KAKENHI-PROJECT-23K14946, KAKENHI-PROJECT-22K07882, KAKENHI-PROJECT-20K08224
[Journal Article] Expression analyses of WAC, a responsible gene for neurodevelopmental disorders, during mouse brain development2023
- Author(s)
  Nishikawa Masashi、Matsuki Tohru、Hamada Nanako、Nakayama Atsuo、Ito Hidenori、Nagata Koh-ichi
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 56 Issue: 4 Pages: 266-273
- DOI
  10.1007/s00795-023-00364-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19498, KAKENHI-PROJECT-23K14946, KAKENHI-PROJECT-20K08200, KAKENHI-PROJECT-20K08224, KAKENHI-PROJECT-23K24310
[Journal Article] Expression Analyses of Rich2/Arhgap44, a Rho Family GTPase-Activating Protein, during Mouse Brain Development.2023
- Author(s)
  Goto N, Nishikawa M, Ito H, Noda M, Hamada N, Tabata H, Kinoshita M, Nagata K-I
- Journal Title
  
  Dev. Neurosci.
  
  Volume: 45 Issue: 1 Pages: 19-26
- DOI
  10.1159/000529051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08271, KAKENHI-PROJECT-19K07059, KAKENHI-PROJECT-21K15895, KAKENHI-PROJECT-22K19498, KAKENHI-PROJECT-20K08200
[Journal Article] A missense variant at the RAC1-PAK1 binding site of RAC1 inactivates downstream signaling in VACTERL association2023
- Author(s)
  Seyama Rie、Nishikawa Masashi、Ogata Kazuhiro、Nagata Koh-ichi、Matsumoto Naomichi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 9789-9789
- DOI
  10.1038/s41598-023-36381-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19498, KAKENHI-PROJECT-23K18278, KAKENHI-PROJECT-23K14946, KAKENHI-PROJECT-21K06051, KAKENHI-PROJECT-23K07229, KAKENHI-PROJECT-23K27520, KAKENHI-PROJECT-23K27568
[Journal Article] Impaired Function of PLEKHG2, a Rho-Guanine Nucleotide-Exchange Factor, Disrupts Corticogenesis in Neurodevelopmental Phenotypes.2022
- Author(s)
  Nishikawa M, Ito H, Tabata H, Ueda H, Nagata KI.
- Journal Title
  
  Cells
  
  Volume: 16 Issue: 4 Pages: 696-696
- DOI
  10.3390/cells11040696
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07043, KAKENHI-PROJECT-20K22888, KAKENHI-PROJECT-19K07059, KAKENHI-PROJECT-22K06579, KAKENHI-PROJECT-22K19498, KAKENHI-PROJECT-20K21589, KAKENHI-PROJECT-23K24310
[Journal Article] Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes2022
- Author(s)
  Scala Marcello et al.
- Journal Title
  
  Brain
  
  Volume: 145 Issue: 9 Pages: 3308-3327
- DOI
  10.1093/brain/awac106
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07309, KAKENHI-PROJECT-22K19498, KAKENHI-PROJECT-19K07059, KAKENHI-PROJECT-20K21589, KAKENHI-PROJECT-21K15895, KAKENHI-PROJECT-19H03629, KAKENHI-PROJECT-23K24310
[Journal Article] Gain-of-function p.F28S variant in<i>RAC3</i>disrupts neuronal differentiation, migration and axonogenesis during cortical development, leading to neurodevelopmental disorder2022
- Author(s)
  Nishikawa Masashi、Scala Marcello、Umair Muhammad、Ito Hidenori、Waqas Ahmed、Striano Pasquale、Zara Federico、Costain Gregory、Capra Valeria、Nagata Koh-ichi
- Journal Title
  
  Journal of Medical Genetics
  
  Volume: 60 Issue: 3 Pages: 223-232
- DOI
  10.1136/jmedgenet-2022-108483
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19498, KAKENHI-PROJECT-19K07059, KAKENHI-PROJECT-20K21589, KAKENHI-PROJECT-21K15895, KAKENHI-PROJECT-19H03629, KAKENHI-PROJECT-23K24310
[Journal Article] Expression analyses of Rac3, a Rho family small GTPase, during mouse brain development.2022
- Author(s)
  Nishikawa M, Ito H, Noda M, Hamada N, Tabata H, Nagata K.
- Journal Title
  
  Dev Neurosci
  
  Volume: 44 Issue: 1 Pages: 49-58
- DOI
  10.1159/000521168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07059, KAKENHI-PROJECT-20K08271, KAKENHI-PROJECT-20K21589, KAKENHI-PROJECT-21K15895, KAKENHI-PROJECT-19H03629
[Journal Article] Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What’s behind Neuro-RACopathies2021
- Author(s)
  Scala Marcello、Nishikawa Masashi、Nagata Koh-ichi、Striano Pasquale
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 12 Pages: 3395-3395
- DOI
  10.3390/cells10123395
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15895
[Journal Article] Expression Analyses of Mediator Complex Subunit 13-Like: A Responsible Gene for Neurodevelopmental Disorders during Mouse Brain Development2021
- Author(s)
  Hamada Nanako、Iwamoto Ikuko、Nishikawa Masashi、Nagata Koh-ichi
- Journal Title
  
  Developmental Neuroscience
  
  Volume: - Issue: 1 Pages: 1-10
- DOI
  10.1159/000515188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22888, KAKENHI-PROJECT-19H03629, KAKENHI-PROJECT-20K08200, KAKENHI-PROJECT-20K21589
[Journal Article] Expression analyses of PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, during mouse brain development2021
- Author(s)
  Nishikawa Masashi、Ito Hidenori、Noda Mariko、Hamada Nanako、Tabata Hidenori、Nagata Koh-ichi
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: - Issue: 2 Pages: 146-155
- DOI
  10.1007/s00795-020-00275-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22888, KAKENHI-PROJECT-19H03629, KAKENHI-PROJECT-19K07059, KAKENHI-PROJECT-20K08200, KAKENHI-PROJECT-20K08271, KAKENHI-PROJECT-20K21589
[Presentation] Rac-グアニンヌクレオチド交換因子 Prex1 の神経発達における生理機能2023
- Author(s)
  鳥居紗帆, 西川将司, 内山由理, 後藤直樹, 伊東秀記, 上田浩, 松本直通, 永田浩一, 木下専
- Organizer
  第64回日本神経病理学会総会学術研究会/ 第66回日本神経化学会大会合同大会 2023年7月7日
- Data Source
  KAKENHI-PROJECT-23K14946
[Presentation] 神経発達におけるRac1制御分子Rich2の発現プロファイル解析2022
- Author(s)
  後藤直樹, 西川将司, 木下専, 永田浩一
- Organizer
  第54回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] PLEKHG2遺伝子変異による神経発達障害の発症機構の形態的解析2022
- Author(s)
  永田浩一, 西川将司, 伊東秀記, 田畑秀典
- Organizer
  第54回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K22888
[Presentation] Impaired function of PLEKHG2, a Rho-guanine nucleotide-exchange factor, disrupts corticogenesis in neurodevelopmental phenotypes2022
- Author(s)
  西川将司, 伊東秀記, 田畑秀典, 永田浩一
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-20K22888
[Presentation] 知的障害責任分子RAC3による神経発達障害の病態メカニズム2022
- Author(s)
  西川将司, 伊東秀記, 田畑秀典, 永田浩一
- Organizer
  第86回日本生化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] RAC3遺伝子変異は神経発達過程の大脳皮質形成を障害する2022
- Author(s)
  西川将司, 伊東秀記, 田畑秀典, 永田浩一
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes2022
- Author(s)
  Koh-ichi Nagata, Masashi Nishikawa, Hidenori Ito
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] 知的障害責任分子RAC3による神経発達障害の病態メカニズム2022
- Author(s)
  西川将司, 伊東秀記, 田畑秀典, 永田浩一
- Organizer
  第86回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] 知的障害責任分子群RACファミリーの大脳発達における生理機能と分子病態機構の解明2022
- Author(s)
  西川将司
- Organizer
  第20回東海小児遺伝カンファレンス 2022年2月19日
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] Rac制御分子Rich2は神経発達に伴って発現分布が変化する2022
- Author(s)
  後藤直樹, 西川将司, 伊東秀記, 田畑秀典, 木下専, 永田浩一
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] アダプタータンパク質NCK2によるSH3ドメインを介したRho活性化因子PLEKHG1の活性制御2021
- Author(s)
  井藤拓哉、後藤未沙紀、中野駿、西川将司、山川央、長瀬隆弘、上田浩
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K22888
[Presentation] Pathophysiological significance of RAC3 variants in neurodevelopmental disorders2021
- Author(s)
  西川将司, 伊東秀記, 田畑秀典, 永田浩一
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] 発達障害責任遺伝子Rac3の神経組織における発現解析2021
- Author(s)
  西川将司, 伊東秀記, 野田万理子, 浜田奈々子, 田畑秀典, 永田浩
- Organizer
  第53回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] 知的障害責任分子RAC3の大脳発達における生理機能と分子病態機構の解明2021
- Author(s)
  西川将司
- Organizer
  名古屋大学脳とこころの研究センター第6回拡大ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] 知的障害責任分子RAC3の大脳発達における生理機能と分子病態機構の解明2021
- Author(s)
  西川将司, 伊東秀記, 田畑秀典, 永田浩一
- Organizer
  第43回神経組織培養研究会
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] 知的障害責任分子RAC3の大脳発達における生理機能と分子病態機構の解明2021
- Author(s)
  永田浩一, 西川将司
- Organizer
  第53回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K15895
[Presentation] 発達障害責任遺伝子PLEKHG2の神経組織における発現解析2020
- Author(s)
  永田浩一、西川将司、伊東秀記、野田万理子、浜田奈々子、田畑秀典
- Organizer
  日本臨床分子形態学会
- Data Source
  KAKENHI-PROJECT-20K22888

1. NODA Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 上田浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 常浦祐未

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 永田浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. 伊東秀記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NISHIKAWA Masashi 西川 将司

Nishikawa Masashi 西川 将司

Research Projects

Research Products

Co-Researchers

小児知的障害の遺伝子変異から読み解く神経発生におけるRHOGの役割と病態機序Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Underlying pathomechanisms of Cdc42 variants in microcephaly and cortical malformation with intellectual disabilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological functions and pathogenic mechanisms of Rac3, an intellectual disability-associated G protein, in cerebral developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological analyses of PLEKHG2, a responsible gene for neurodevelopmental disorders, during corticogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Live Imaging of Migrating Neurons and Glial Progenitors Visualized by in Utero Electroporation2024

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] A Novel Constitutively Active c.98G>C, p.(R33P) Variant in RAB11A Associated with Intellectual Disability Promotes Neuritogenesis and Affects Oligodendroglial Arborization2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression analyses of WAC, a responsible gene for neurodevelopmental disorders, during mouse brain development2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression Analyses of Rich2/Arhgap44, a Rho Family GTPase-Activating Protein, during Mouse Brain Development.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A missense variant at the RAC1-PAK1 binding site of RAC1 inactivates downstream signaling in VACTERL association2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired Function of PLEKHG2, a Rho-Guanine Nucleotide-Exchange Factor, Disrupts Corticogenesis in Neurodevelopmental Phenotypes.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gain-of-function p.F28S variant in<i>RAC3</i>disrupts neuronal differentiation, migration and axonogenesis during cortical development, leading to neurodevelopmental disorder2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression analyses of Rac3, a Rho family small GTPase, during mouse brain development.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What’s behind Neuro-RACopathies2021

Author(s)

Journal Title

DOI

Data Source

NISHIKAWA Masashi 西川将司

Nishikawa Masashi 西川将司