Lee Yongchan 李勇燦

Researcher Number	00894932
Other IDs
Affiliation (Current)	2026: 横浜市立大学, 生命医科学研究科, 助教 2026: 横浜市立大学, 理学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 横浜市立大学, 生命医科学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related Except Principal Investigator Basic Section 38050:Food sciences-related / Transformative Research Areas, Section (II) / Basic Section 43030:Functional biochemistry-related
Keywords	Principal Investigator 構造解析 / クライオ電子顕微鏡 / 阻害剤 / Cryo-EM / 痛風 / 阻害薬 / 輸送体 / 尿酸 / 生体膜 / ナノディスク / アミノ酸輸送体 … More Except Principal Investigator … More 栄養素 / トランスポーター / タンパク質複合体 / 代謝 / 吸収 / 構造生物学 / クライオ電子顕微鏡 / 輸送体 / 膜タンパク質 / mass spectrometry / amino acid / exchanger / homeostasis / HATs / structure / kidney / transporter / amino acids / cystinuria / マルチオミクス / 構造解析 / 病気 / 恒常性 / 腎臓 / 構造 / アミノ酸 Less

トランスポータークラスターの分子機序解明による栄養素吸収の理解
- Principal Investigator
  
  Wiriyasermkul Pattama
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Iwate University
クライオ電子顕微鏡による膜輸送タンパク質の動的構造解析と機能制御
- Principal Investigator
  
  西澤知宏
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Yokohama City University
Elucidating structural basis of substrate recognition by urate transportersPrincipal Investigator
- Principal Investigator
  
  李勇燦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Yokohama City University
Molecular mechanism of amino acid harmonization: a paradigm of heterodimeric amino acid transporters
- Principal Investigator
  
  Wiriyasermkul Pattama
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Iwate University
  Jikei University School of Medicine
Structural and functional elucidation of L-type amino acid transporter under lipid environmentPrincipal Investigator
- Principal Investigator
  
  Lee Yongchan
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Yokohama City University

All 2025 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Structural basis of urate transport by glucose transporter 92025
- Author(s)
  Matsushita Daiki、Toyoda Yu、Lee Yongchan、Aoi Maeda、Matsuo Hirotaka、Takada Tappei、Nishizawa Tomohiro
- Journal Title
  
  Cell Reports
  
  Volume: 44 Issue: 4 Pages: 115514-115514
- DOI
  10.1016/j.celrep.2025.115514
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27132, KAKENHI-PROJECT-24K18064
[Journal Article] 多階層的アプローチによる栄養素輸送システムの解明2024
- Author(s)
  ウィリヤサムクンパッタマ，永森收志
- Volume
  42
- Pages
  2845
- DOI
  10.18958/7569-00001-0001741-00
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-22K06150
[Journal Article] A “Multi-hierarchical Approach” to elucidate the functions of membrane transport proteins in living organisms2024
- Author(s)
  ウィリヤサムクンパッタマ、永森收志
- Journal Title
  
  生化学
  
  Volume: 96 Issue: 5 Pages: 695-700
- DOI
  10.14952/SEIKAGAKU.2024.960695
- ISSN
  0037-1017
- Year and Date
  2024-10-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24H01334, KAKENHI-PROJECT-22K06150, KAKENHI-PROJECT-24K02888
[Journal Article] Structural basis of anticancer drug recognition and amino acid transport by LAT12023
- Author(s)
  Lee Yongchan、Jin Chunhuan、Ohgaki Ryuichi、Xu Minhui、Ogasawara Satoshi、Warshamanage Rangana、Yamashita Keitaro、Murshudov Garib、Nureki Osamu、Murata Takeshi、Kanai Yoshikatsu
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2023.12.03.567112
- Open Access
- Data Source
  KAKENHI-PROJECT-21K15031
[Journal Article] Ca2+-mediated higher-order assembly of b0,+AT-rBAT is a key step for system b0,+ biogenesis and cystinuria2021
- Author(s)
  Lee Yongchan、Wiriyasermkul Pattama、Moriyama Satomi、Mills Deryck J.、Kuehlbrandt Werner、Nagamori Shushi
- Journal Title
  
  bioRxiv
  
  Volume: －
- DOI
  10.1101/2021.05.06.443019
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15031
[Presentation] SLCトランスポーターが示す多選択的な薬物相互作用の構造基盤2025
- Author(s)
  李勇燦
- Organizer
  日本薬学会第145年会
- Invited
- Data Source
  KAKENHI-PROJECT-24K18064
[Presentation] Structural Pharmacology of SLC Transporters2024
- Author(s)
  Yongchan Lee
- Organizer
  ISDD & KSSB Joint Symposium 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K18064
[Presentation] Cryo-EMによるSLC輸送体の構造薬学2024
- Author(s)
  李勇燦
- Organizer
  第97回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-24K18064
[Presentation] クライオ電子顕微鏡によるアミノ酸輸送体の構造薬学的研究2023
- Author(s)
  李勇燦
- Organizer
  日本顕微鏡学会第66回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K15031
[Presentation] 哺乳類が持つヘテロ複合体型アミノ酸輸送体の構造解析2023
- Author(s)
  李勇燦
- Organizer
  第23回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15031
[Presentation] Structural studies of SLC amino acid transporters relevant to health and diseases2023
- Author(s)
  Yongchan Lee
- Organizer
  International Conference on Biological Physics (ICBP2023)
- Invited
- Data Source
  KAKENHI-PROJECT-21K15031
[Presentation] Structural Studies of Membrane Transporters Relevant to Health and Diseases2022
- Author(s)
  Yongchan Lee
- Organizer
  2022 China-Japan-Korea Youth Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15031
[Presentation] Cryo-EM Structure of L-type Amino Acid Transporter 2 (LAT2)2022
- Author(s)
  Saki Takahashi, Yongchan Lee, Satoshi Ogasawara, Takeshi Murata, Yoshikatsu Kanai, Tomohiro Nishizawa
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15031
[Presentation] 脂質二重膜に埋め込まれた膜タンパク質のCryo-EM構造解析2021
- Author(s)
  李勇燦
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15031
[Presentation] Structural mechanisms of heteromeric amino acid transporters revealed by cryo-EM and insights into cystinuria2021
- Author(s)
  Yongchan Lee
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15031

1. Wiriyasermkul Pattama (80825836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 西澤知宏 (80599077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 西山賢一 (80291334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Lee Yongchan 李 勇燦

Research Projects

Research Products

Co-Researchers

トランスポータークラスターの分子機序解明による栄養素吸収の理解

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

クライオ電子顕微鏡による膜輸送タンパク質の動的構造解析と機能制御

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating structural basis of substrate recognition by urate transportersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of amino acid harmonization: a paradigm of heterodimeric amino acid transporters

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural and functional elucidation of L-type amino acid transporter under lipid environmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Structural basis of urate transport by glucose transporter 92025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 多階層的アプローチによる栄養素輸送システムの解明2024

Author(s)

Volume

Pages

DOI

Language

Data Source

[Journal Article] A “Multi-hierarchical Approach” to elucidate the functions of membrane transport proteins in living organisms2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Structural basis of anticancer drug recognition and amino acid transport by LAT12023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ca2+-mediated higher-order assembly of b0,+AT-rBAT is a key step for system b0,+ biogenesis and cystinuria2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] SLCトランスポーターが示す多選択的な薬物相互作用の構造基盤2025

Author(s)

Organizer

Data Source

[Presentation] Structural Pharmacology of SLC Transporters2024

Author(s)

Organizer

Data Source

[Presentation] Cryo-EMによるSLC輸送体の構造薬学2024

Author(s)

Organizer

Data Source

[Presentation] クライオ電子顕微鏡によるアミノ酸輸送体の構造薬学的研究2023

Author(s)

Organizer

Data Source

Lee Yongchan 李勇燦