Wiriyasermkul Pattama ＷｉｒｉｙａｓｅｒｍｋｕｌＰａｔｔａｍａ

Researcher Number	80825836
Other IDs
Affiliation (Current)	2023: 東京慈恵会医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2022: 東京慈恵会医科大学, 医学部, 助教 2020: 東京慈恵会医科大学, 医学部, 特任助教 2019: 奈良県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Basic Section 53040:Nephrology-related / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator cystinuria / amino acid / transporter / structure / kidney / biogenesis / calcium / cryo-EM / cystine / Transporter … More / Cystinuria / Structure / Amino acids / SLC7 / Kidney disease / Cystine / Mutation / mass spectrometry … More Except Principal Investigator 細胞老化 / 細胞増殖 / 多発性嚢胞腎 / トランスポーター / マルチオミクス / プロテオミクス / D－アミノ酸 Less

Molecular mechanism of amino acid harmonization: a paradigm of heterodimeric amino acid transportersPrincipal Investigator
- Principal Investigator
  
  Wiriyasermkul Pattama
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Jikei University School of Medicine
階層的アプローチによる膜輸送体の隠されている生理的基質の解明
- Principal Investigator
  
  永森收志
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Jikei University School of Medicine
Pathophysiological roles of cell senescence related gene in the polycystic kidney disease
- Principal Investigator
  
  波多野亮
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Chiba University
Molecular mechanism of the pathogenic protein interaction at the C-terminus of amino acid transporter b0,+AT/SLC7A9 in Japanese-type cystinuriaPrincipal Investigator
- Principal Investigator
  
  Wiriyasermkul Pattama
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Jikei University School of Medicine
  Nara Medical University

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Ca2+-mediated higher-order assembly of heterodimers in amino acid transport system b0,+ biogenesis and cystinuria2022
- Author(s)
  Lee Yongchan、Wiriyasermkul Pattama、Kongpracha Pornparn、Moriyama Satomi、Mills Deryck J.、Kuhlbrandt Werner、Nagamori Shushi
- Journal Title
  
  Nature Communications
  
  Volume: -
- DOI
  10.1038/s41467-022-30293-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07373
[Journal Article] Simple but efficacious enrichment of integral membrane proteins and their interactions for in-depth membrane proteomics2022
- Author(s)
  Kongpracha Pornparn、Wiriyasermkul Pattama、Isozumi Noriyoshi、Moriyama Satomi、Kanai Yoshikatsu、Nagamori Shushi
- Journal Title
  
  Molecular and Cellular Proteomics
  
  Volume: - Pages: 100206-100206
- DOI
  10.1016/j.mcpro.2022.100206
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07373, KAKENHI-PROJECT-19H03407
[Journal Article] ヒト栄養素トランスポーターと分子標的創薬研究2020
- Author(s)
  永森收志, 森山理美, パッタマウィリヤサムクン
- Journal Title
  
  化学と生物
  
  Volume: 58 Pages: 520-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07373
[Journal Article] D-Serine, an emerging biomarker of kidney diseases, is a hidden substrate of sodium-coupled monocarboxylate transporters2020
- Author(s)
  Wiriyasermkul Pattama、Moriyama Satomi、Tanaka Yoko、Kongpracha Pornparn、Nakamae Nodoka、Suzuki Masataka、Kimura Tomonori、Mita Masashi、Sasabe Jumpei、Nagamori Shushi
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2020.08.10.244822
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07373
[Journal Article] Membrane transport proteins in melanosomes: Regulation of ions for pigmentation2020
- Author(s)
  Wiriyasermkul Pattama、Moriyama Satomi、Nagamori Shushi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: 1862 Pages: 183318-183318
- DOI
  10.1016/j.bbamem.2020.183318
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07373
[Journal Article] Consensus mutagenesis approach improves the thermal stability of system x c ? transporter, xCT , and enables cryo‐EM analyses2020
- Author(s)
  Oda Kazumasa、Lee Yongchan、Wiriyasermkul Pattama、Tanaka Yoko、Takemoto Mizuki、Yamashita Keitaro、Nagamori Shushi、Nishizawa Tomohiro、Nureki Osamu
- Journal Title
  
  Protein Science
  
  Volume: 29 Pages: 2398-2407
- DOI
  10.1002/pro.3966
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07373, KAKENHI-PROJECT-18J21256, KAKENHI-PROJECT-20H03216
[Journal Article] Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc2019
- Author(s)
  Lee Yongchan、Wiriyasermkul Pattama、Jin Chunhuan、Quan Lili、Ohgaki Ryuichi、Okuda Suguru、Kusakizako Tsukasa、Nishizawa Tomohiro、Oda Kazumasa、Ishitani Ryuichiro、Yokoyama Takeshi、Nakane Takanori、Shirouzu Mikako、Endou Hitoshi、Nagamori Shushi、Kanai Yoshikatsu、Nureki Osamu
- Journal Title
  
  Nat. Struct. Mol. Biol.
  
  Volume: 26 Pages: 510-517
- DOI
  10.1038/s41594-019-0237-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06931, KAKENHI-PROJECT-19K07373, KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-18K19429, KAKENHI-PROJECT-16H06294
[Presentation] Multi-hierarchical approach unveils unexpected transport proteins for D-serine, a biomarker for kidney injury2022
- Author(s)
  Wiriyasermkul Pattama
- Organizer
  Kanazawa University International Web Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-19K07373
[Presentation] A combinatorial approach to enlighten hidden substrates of the renowned transporters2021
- Author(s)
  Wiriyasermkul Pattama
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07373
[Presentation] Ca2+を介した高次構造形成は、ヘテロ二量体アミノ酸トランスポーター b0,+AT-rBATの生合成において重要なステップである2021
- Author(s)
  Wiriyasermkul Pattama、Lee Yongchan、Kongpracha Pornparn、Kuhlbrandt Werner、Nagamori Shushi
- Organizer
  第 138 回成医会総会
- Data Source
  KAKENHI-PROJECT-19K07373
[Presentation] Biogenesis and function of rBAT-b0,+AT: a heterodimeric amino acid transporter2021
- Author(s)
  Wiriyasermkul Pattama、Lee Yongchan、Kuhlbrandt Werner、Nagamori Shushi
- Organizer
  2021 年度生理研研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07373
[Presentation] Function and structure of heterodimeric amino acid transporters2020
- Author(s)
  Wiriyasermkul P, Nagamori S.
- Organizer
  Ron Kaback博士追悼記念第二回細胞形成研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07373
[Presentation] Function and structure of heterodimeric amino acid transporters: toward the understanding of their physiological properties and pharmaceutical relevance2020
- Author(s)
  Wiriyasermkul P, Nagamori S
- Organizer
  The 140th Annual Meeting of the Pharmaceutical Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-19K07373
[Presentation] Function and structure of heterodimeric amino acid transporters2019
- Author(s)
  Wiriyasermkul P, Nagamori S
- Organizer
  生体コモンスペース研究会
- Data Source
  KAKENHI-PROJECT-19K07373
[Presentation] Combination of structural and biochemical approaches reveals transport mechanism of Nucleobase/ascorbate transporter2019
- Author(s)
  Wiriyasermkul P, Quick M
- Organizer
  The 92nd annual meeting of the Japanese Biochemical Society
- Invited
- Data Source
  KAKENHI-PROJECT-19K07373
[Presentation] Proteomics and phosphoproteomics of brain organoids2019
- Author(s)
  Wiriyasermkul P, Nagamori S
- Organizer
  ASUKA symposium
- Invited
- Data Source
  KAKENHI-PROJECT-19K07373

1. Kongpracha Pornparn (70817767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 波多野亮 (60521713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 伊藤素行 (20377906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 三木隆司 (50302568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 永森收志 (90467572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 笹部潤平 (10398612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 西山賢一 (80291334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 李勇燦 (00894932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OHGAKI Ryuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. ISHITANI Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. NISHIZAWA Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. コンプラシャポーンパン

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
13. 金井好克

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 奥田傑

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 濡木理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Wiriyasermkul Pattama Ｗｉｒｉｙａｓｅｒｍｋｕｌ Ｐａｔｔａｍａ

Research Projects

Research Products

Co-Researchers

Molecular mechanism of amino acid harmonization: a paradigm of heterodimeric amino acid transportersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

階層的アプローチによる膜輸送体の隠されている生理的基質の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological roles of cell senescence related gene in the polycystic kidney disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of the pathogenic protein interaction at the C-terminus of amino acid transporter b0,+AT/SLC7A9 in Japanese-type cystinuriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Ca2+-mediated higher-order assembly of heterodimers in amino acid transport system b0,+ biogenesis and cystinuria2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simple but efficacious enrichment of integral membrane proteins and their interactions for in-depth membrane proteomics2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ヒト栄養素トランスポーターと分子標的創薬研究2020

Author(s)

Journal Title

Data Source

[Journal Article] D-Serine, an emerging biomarker of kidney diseases, is a hidden substrate of sodium-coupled monocarboxylate transporters2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Membrane transport proteins in melanosomes: Regulation of ions for pigmentation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Consensus mutagenesis approach improves the thermal stability of system x c ? transporter, xCT , and enables cryo‐EM analyses2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Multi-hierarchical approach unveils unexpected transport proteins for D-serine, a biomarker for kidney injury2022

Author(s)

Organizer

Data Source

[Presentation] A combinatorial approach to enlighten hidden substrates of the renowned transporters2021

Author(s)

Organizer

Data Source

[Presentation] Ca2+を介した高次構造形成は、ヘテロ二量体アミノ酸トランスポーター b0,+AT-rBATの 生合成において重要なステップである2021

Author(s)

Organizer

Data Source

[Presentation] Biogenesis and function of rBAT-b0,+AT: a heterodimeric amino acid transporter2021

Author(s)

Organizer

Data Source

[Presentation] Function and structure of heterodimeric amino acid transporters2020

Author(s)

Wiriyasermkul Pattama ＷｉｒｉｙａｓｅｒｍｋｕｌＰａｔｔａｍａ

[Presentation] Ca2+を介した高次構造形成は、ヘテロ二量体アミノ酸トランスポーター b0,+AT-rBATの生合成において重要なステップである2021