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Wiriyasermkul Pattama  Wiriyasermkul Pattama

ORCIDConnect your ORCID iD *help
Researcher Number 80825836
Other IDs
Affiliation (Current) 2023: 東京慈恵会医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2020 – 2022: 東京慈恵会医科大学, 医学部, 助教
2020: 東京慈恵会医科大学, 医学部, 特任助教
2019: 奈良県立医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 48040:Medical biochemistry-related / Basic Section 43030:Functional biochemistry-related
Except Principal Investigator
Basic Section 53040:Nephrology-related / Basic Section 59040:Nutrition science and health science-related
Keywords
Principal Investigator
cystinuria / amino acid / transporter / structure / kidney / biogenesis / calcium / cryo-EM / cystine / Transporter … More / Cystinuria / Structure / Amino acids / SLC7 / Kidney disease / Cystine / Mutation / mass spectrometry … More
Except Principal Investigator
細胞老化 / 細胞増殖 / 多発性嚢胞腎 / トランスポーター / マルチオミクス / プロテオミクス / D-アミノ酸 Less
  • Research Projects

    (4 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (15 People)
  •  Molecular mechanism of amino acid harmonization: a paradigm of heterodimeric amino acid transportersPrincipal Investigator

    • Principal Investigator
      Wiriyasermkul Pattama
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Jikei University School of Medicine
  •  階層的アプローチによる膜輸送体の隠されている生理的基質の解明

    • Principal Investigator
      永森 收志
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Jikei University School of Medicine
  •  Pathophysiological roles of cell senescence related gene in the polycystic kidney disease

    • Principal Investigator
      波多野 亮
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Chiba University
  •  Molecular mechanism of the pathogenic protein interaction at the C-terminus of amino acid transporter b0,+AT/SLC7A9 in Japanese-type cystinuriaPrincipal Investigator

    • Principal Investigator
      Wiriyasermkul Pattama
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Jikei University School of Medicine
      Nara Medical University

All 2022 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] Ca2+-mediated higher-order assembly of heterodimers in amino acid transport system b0,+ biogenesis and cystinuria2022

    • Author(s)
      Lee Yongchan、Wiriyasermkul Pattama、Kongpracha Pornparn、Moriyama Satomi、Mills Deryck J.、Kuhlbrandt Werner、Nagamori Shushi
    • Journal Title

      Nature Communications

      Volume: -

    • DOI

      10.1038/s41467-022-30293-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Journal Article] Simple but efficacious enrichment of integral membrane proteins and their interactions for in-depth membrane proteomics2022

    • Author(s)
      Kongpracha Pornparn、Wiriyasermkul Pattama、Isozumi Noriyoshi、Moriyama Satomi、Kanai Yoshikatsu、Nagamori Shushi
    • Journal Title

      Molecular and Cellular Proteomics

      Volume: - Pages: 100206-100206

    • DOI

      10.1016/j.mcpro.2022.100206

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07373, KAKENHI-PROJECT-19H03407
  • [Journal Article] ヒト栄養素トランスポーターと分子標的創薬研究2020

    • Author(s)
      永森 收志, 森山 理美, パッタマ ウィリヤサムクン
    • Journal Title

      化学と生物

      Volume: 58 Pages: 520-528

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Journal Article] D-Serine, an emerging biomarker of kidney diseases, is a hidden substrate of sodium-coupled monocarboxylate transporters2020

    • Author(s)
      Wiriyasermkul Pattama、Moriyama Satomi、Tanaka Yoko、Kongpracha Pornparn、Nakamae Nodoka、Suzuki Masataka、Kimura Tomonori、Mita Masashi、Sasabe Jumpei、Nagamori Shushi
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2020.08.10.244822

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Journal Article] Membrane transport proteins in melanosomes: Regulation of ions for pigmentation2020

    • Author(s)
      Wiriyasermkul Pattama、Moriyama Satomi、Nagamori Shushi
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Biomembranes

      Volume: 1862 Pages: 183318-183318

    • DOI

      10.1016/j.bbamem.2020.183318

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Journal Article] Consensus mutagenesis approach improves the thermal stability of system x c ? transporter, xCT , and enables cryo‐EM analyses2020

    • Author(s)
      Oda Kazumasa、Lee Yongchan、Wiriyasermkul Pattama、Tanaka Yoko、Takemoto Mizuki、Yamashita Keitaro、Nagamori Shushi、Nishizawa Tomohiro、Nureki Osamu
    • Journal Title

      Protein Science

      Volume: 29 Pages: 2398-2407

    • DOI

      10.1002/pro.3966

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07373, KAKENHI-PROJECT-18J21256, KAKENHI-PROJECT-20H03216
  • [Journal Article] Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc2019

    • Author(s)
      Lee Yongchan、Wiriyasermkul Pattama、Jin Chunhuan、Quan Lili、Ohgaki Ryuichi、Okuda Suguru、Kusakizako Tsukasa、Nishizawa Tomohiro、Oda Kazumasa、Ishitani Ryuichiro、Yokoyama Takeshi、Nakane Takanori、Shirouzu Mikako、Endou Hitoshi、Nagamori Shushi、Kanai Yoshikatsu、Nureki Osamu
    • Journal Title

      Nat. Struct. Mol. Biol.

      Volume: 26 Pages: 510-517

    • DOI

      10.1038/s41594-019-0237-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06931, KAKENHI-PROJECT-19K07373, KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-18K19429, KAKENHI-PROJECT-16H06294
  • [Presentation] Multi-hierarchical approach unveils unexpected transport proteins for D-serine, a biomarker for kidney injury2022

    • Author(s)
      Wiriyasermkul Pattama
    • Organizer
      Kanazawa University International Web Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Presentation] A combinatorial approach to enlighten hidden substrates of the renowned transporters2021

    • Author(s)
      Wiriyasermkul Pattama
    • Organizer
      第94回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Presentation] Ca2+を介した高次構造形成は、ヘテロ二量体アミノ酸トランスポーター b0,+AT-rBATの 生合成において重要なステップである2021

    • Author(s)
      Wiriyasermkul Pattama、Lee Yongchan、Kongpracha Pornparn、Kuhlbrandt Werner、Nagamori Shushi
    • Organizer
      第 138 回成医会総会
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Presentation] Biogenesis and function of rBAT-b0,+AT: a heterodimeric amino acid transporter2021

    • Author(s)
      Wiriyasermkul Pattama、Lee Yongchan、Kuhlbrandt Werner、Nagamori Shushi
    • Organizer
      2021 年度 生理研研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Presentation] Function and structure of heterodimeric amino acid transporters2020

    • Author(s)
      Wiriyasermkul P, Nagamori S.
    • Organizer
      Ron Kaback博士追悼記念 第二回細胞形成研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Presentation] Function and structure of heterodimeric amino acid transporters: toward the understanding of their physiological properties and pharmaceutical relevance2020

    • Author(s)
      Wiriyasermkul P, Nagamori S
    • Organizer
      The 140th Annual Meeting of the Pharmaceutical Society of Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Presentation] Function and structure of heterodimeric amino acid transporters2019

    • Author(s)
      Wiriyasermkul P, Nagamori S
    • Organizer
      生体コモンスペース研究会
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Presentation] Combination of structural and biochemical approaches reveals transport mechanism of Nucleobase/ascorbate transporter2019

    • Author(s)
      Wiriyasermkul P, Quick M
    • Organizer
      The 92nd annual meeting of the Japanese Biochemical Society
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07373
  • [Presentation] Proteomics and phosphoproteomics of brain organoids2019

    • Author(s)
      Wiriyasermkul P, Nagamori S
    • Organizer
      ASUKA symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07373
  • 1.  Kongpracha Pornparn (70817767)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  波多野 亮 (60521713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  伊藤 素行 (20377906)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  三木 隆司 (50302568)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  永森 收志 (90467572)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  笹部 潤平 (10398612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  西山 賢一 (80291334)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  李 勇燦 (00894932)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OHGAKI Ryuichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  ISHITANI Ryuichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  NISHIZAWA Tomohiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  コンプラシャ ポーンパン
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 13.  金井 好克
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 14.  奥田 傑
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  濡木 理
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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