Tajima Ayasa 田島彩沙

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TAJIMA AYASA 田島彩沙

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Researcher Number	20780688
Other IDs
Affiliation (Current)	2026: 東京慈恵会医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 東京慈恵会医科大学, 医学部, 助教 2017 – 2019: 東京慈恵会医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Metabolomics Except Principal Investigator Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator ポリアミン / ポリアミン代謝 / 核内受容体 / 動脈硬化 / DHA / ドコサヘキサエン酸 / 脂質 / 3T3-L1 / 脂肪酸 / 脂質代謝 / 肥満 / ATPクエン酸リアーゼ / アンチザイム … More Except Principal Investigator … More メタボロミクス / プロテオミクス / プロテオリポソーム / 多階層的解析 / 輸送システム / トランスポーター Less

生理活性物質の吸収メカニズムを担う輸送体分子群の同定と機能解析基盤の確立
- Principal Investigator
  
  永森收志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Jikei University School of Medicine
ポリアミンバランスの破綻がもたらす細胞死メカニズムの解析Principal Investigator
- Principal Investigator
  
  田島彩沙
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Jikei University School of Medicine
Molecular Biological Mechanisms Underlying the Anti-atherosclerotic Effects of Docosahexaenoic AcidPrincipal Investigator
- Principal Investigator
  
  Tajima Ayasa
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Jikei University School of Medicine
Elucidation of the relationship between polyamine synthesis and fatty acid synthesis in obesity formation and the investigation of drug targetsPrincipal Investigator
- Principal Investigator
  
  TAJIMA AYASA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Jikei University School of Medicine

All 2025 2024 2023 2022 2020 2018 2017

All Journal Article Presentation

[Journal Article] Polyamines enhance repeat-associated non-AUG translation from CCUG repeats by stabilizing the tertiary structure of RNA2025
- Author(s)
  Oguro Akihiro、Uemura Takeshi、Machida Kodai、Kitajiri Kanta、Tajima Ayasa、Furuchi Takemitsu、Kawai Gota、Imataka Hiroaki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 301 Issue: 3 Pages: 108251-108251
- DOI
  10.1016/j.jbc.2025.108251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23H04264, KAKENHI-PROJECT-22K07357, KAKENHI-PROJECT-22K11860, KAKENHI-PROJECT-23K23875, KAKENHI-PROJECT-24K14635
[Journal Article] Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase2024
- Author(s)
  Yoshida Saishu、Kawamura Akira、Aoki Katsuhiko、Wiriyasermkul Pattama、Sugimoto Shinya、Tomiyoshi Junnosuke、Tajima Ayasa、Ishida Yamato、Katoh Yohei、Tsukada Takehiro、Tsuneoka Yousuke、Yamada Kohji、Nagamori Shushi、Nakayama Kazuhisa、Yoshida Kiyotsugu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 121 Issue: 28
- DOI
  10.1073/pnas.2320070121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24H01334, KAKENHI-PROJECT-23K21292, KAKENHI-PROJECT-23K18244, KAKENHI-PROJECT-24K02022, KAKENHI-PROJECT-24K02888, KAKENHI-PROJECT-24K10341, KAKENHI-PROJECT-24K14635
[Journal Article] Investigation of the effects of urea cycle amino acids on the expression of ALB and CEBPB in the human hepatocellular carcinoma cell line FLC-42020
- Author(s)
  Takahiko J. Fujimi, Yoshihiro Mezaki, Takahiro Masaki, Ayasa Tajima, Mariko Nakamura, Akira Yoshikawa, Noriyuki Murai, Mamoru Aizawa, Soichi Kojima, Yoshihiro Matsumoto, Hideki Aizaki, Tomokazu Matsuura,
- Journal Title
  
  Human Cell
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16156
[Journal Article] Novel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 22018
- Author(s)
  Murai Noriyuki、Murakami Yasuko、Tajima Ayasa、Matsufuji Senya
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 3005-3005
- DOI
  10.1038/s41598-018-21189-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16156, KAKENHI-PROJECT-15K09666
[Presentation] ATP citrate lyase suppresses the cell death of ornithine decarboxylase-overproducing cells2024
- Author(s)
  Ayasa Tajima
- Organizer
  International Conference on the Biological Roles of Polyamines 2024, 7th Yamada Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K14635
[Presentation] ATP citrate lyase suppresses the cell death of ornithine decarboxylase-overproducing cell line2023
- Author(s)
  Ayasa Tajima
- Organizer
  Gordon Research Conference on Polyamines
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K17836
[Presentation] ポリアミン過剰産生が引き起こす細胞死における ATP クエン酸リアーゼの役割2023
- Author(s)
  田島彩沙
- Organizer
  日本ポリアミン学会第 14 回年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K17836
[Presentation] Docosahexaenoic acid suppresses the generation of reactive oxygen species in endothelial cells: a role for retinoid X receptor RXR2022
- Author(s)
  Ayasa Tajima, Gregory C. Shearer, Hiroshi Yoshida, Senya Matsufuji, A. Catharine Ross
- Organizer
  22nd IUNS-International Congress of Nutrition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K17836
[Presentation] Antizyme and ATP citrate lyase suppresses the cell death of ornithine decarboxylase-overproducing cell line2018
- Author(s)
  Ayasa Tajima
- Organizer
  5th International Conference on Polyamines: Biochemical, Physiological and Clinical Perspectives
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16156
[Presentation] Relationship between ATP citrate lyase and Polyamine metabolism2017
- Author(s)
  Ayasa Tajima
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16156

1. Wiriyasermkul Pattama (80825836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 永森收志 (90467572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NAGAMORI Shushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 町田幸大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tajima Ayasa 田島 彩沙

TAJIMA AYASA 田島 彩沙

Research Projects

Research Products

Co-Researchers

生理活性物質の吸収メカニズムを担う輸送体分子群の同定と機能解析基盤の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ポリアミンバランスの破綻がもたらす細胞死メカニズムの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular Biological Mechanisms Underlying the Anti-atherosclerotic Effects of Docosahexaenoic AcidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the relationship between polyamine synthesis and fatty acid synthesis in obesity formation and the investigation of drug targetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Polyamines enhance repeat-associated non-AUG translation from CCUG repeats by stabilizing the tertiary structure of RNA2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Investigation of the effects of urea cycle amino acids on the expression of ALB and CEBPB in the human hepatocellular carcinoma cell line FLC-42020

Author(s)

Journal Title

Data Source

[Journal Article] Novel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 22018

Author(s)

Journal Title

DOI

Data Source

[Presentation] ATP citrate lyase suppresses the cell death of ornithine decarboxylase-overproducing cells2024

Author(s)

Organizer

Data Source

[Presentation] ATP citrate lyase suppresses the cell death of ornithine decarboxylase-overproducing cell line2023

Author(s)

Organizer

Data Source

[Presentation] ポリアミン過剰産生が引き起こす細胞死における ATP クエン酸リアーゼの役割2023

Author(s)

Organizer

Data Source

[Presentation] Docosahexaenoic acid suppresses the generation of reactive oxygen species in endothelial cells: a role for retinoid X receptor RXR2022

Author(s)

Organizer

Data Source

[Presentation] Antizyme and ATP citrate lyase suppresses the cell death of ornithine decarboxylase-overproducing cell line2018

Author(s)

Organizer

Data Source

[Presentation] Relationship between ATP citrate lyase and Polyamine metabolism2017

Author(s)

Organizer

Data Source

Tajima Ayasa 田島彩沙

TAJIMA AYASA 田島彩沙