Kohno Mikihiro 河野幹寛

… Alternative Names

KOHNO Mikihiro 河野幹寛

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Researcher Number	00906323
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 九州大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 55040:Respiratory surgery-related Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator 腫瘍関連マクロファージ / がん微小環境 / 肺切除 / 原発性肺癌 / 間質性肺炎 / 腫瘍免疫 / 外科切除 / 特発性線維症 / 間質性肺疾患 / 肺癌 … More / 中皮腫 / 免疫療法 / 腫瘍内微小環境 / 悪性胸膜中皮腫 … More Except Principal Investigator 腫瘍免疫 / 代謝酵素 / プロテオミクス / 胸膜中皮腫 / 肺扁平上皮癌 / 腫瘍微小環境 / SLC38A7 / 肺腺癌 / グルタミントランスポーター / 放射線・病理画像診断 / バーチャルスライド / 腫瘍遺伝子変異量 / 免疫チェックポイント阻害薬 / 人工知能（AI） / Radiomics / テクスチャ解析 / 病理画像 / CT画像 / TMB（腫瘍遺伝子変異量） / 肺癌 Less

Overcoming acute exacerbation of interstitial lung diseases and progression of lung cancer by M2 macrophage inhibitionPrincipal Investigator
- Principal Investigator
  
  河野幹寛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kyushu University
次世代プロテオミクスとグルタミン代謝に着目した胸膜中皮腫に対する新規免疫代謝療法
- Principal Investigator
  
  田川哲三
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  National Hospital Organization, Kyushu Medical Center (Clinical Institute)
放射線・病理画像テクスチャ解析を用いた肺癌の腫瘍遺伝子変異量予測モデルの開発
- Principal Investigator
  
  山崎元彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Niigata University
肺扁平上皮癌に対する新規グルタミントランスポーター阻害療法の確立
- Principal Investigator
  
  竹中朋祐
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kyushu University
Development of novel immunotherapy targeting pleural macrophage subsets in malignant pleural mesotheliomaPrincipal Investigator
- Principal Investigator
  
  KOHNO Mikihiro
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kyushu University

All 2025 2023 2022

All Journal Article Presentation

[Journal Article] Comparison of radiological and pathological tumor sizes in resected non-small cell lung cancer2023
- Author(s)
  Nagano Taichi、Takamori Shinkichi、Hashinokuchi Asato、Matsydo Kyoto、Kohno Mikihiro、Miura Naoko、Takenaka Tomoyoshi、Kamitani Takeshi、Shimokawa Mototsugu、Ishigami Kousei、Oda Yoshinao、Yoshizumi Tomoharu
- Journal Title
  
  General Thoracic and Cardiovascular Surgery
  
  Volume: 71 Issue: 12 Pages: 708-714
- DOI
  10.1007/s11748-023-01938-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16572
[Journal Article] Granzyme B (GZMB)-Positive Tumor-Infiltrating Lymphocytes in Lung Adenocarcinoma: Significance as a Prognostic Factor and Association with Immunosuppressive Proteins2023
- Author(s)
  Kinoshita Fumihiko、Takada Kazuki、Wakasu Sho、Saito Shunichi、Hashinokuchi Asato、Matsudo Kyoto、Nagano Taichi、Akamine Takaki、Kohno Mikihiro、Takenaka Tomoyoshi、Shimokawa Mototsugu、Oda Yoshinao、Yoshizumi Tomoharu
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 30 Issue: 12 Pages: 7579-7589
- DOI
  10.1245/s10434-023-14085-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16572
[Journal Article] Transducin Beta-Like 2 is a Potential Driver Gene that Adapts to Endoplasmic Reticulum Stress to Promote Tumor Growth of Lung Adenocarcinoma.2023
- Author(s)
  Kosai K, Masuda T, Kitagawa A, Tobo T, Ono Y, Ando Y, Takahashi J, Haratake N, Kohno M, Takenaka T, Yoshizumi T, Mimori K.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 30(12) Issue: 12 Pages: 7538-7548
- DOI
  10.1245/s10434-023-13864-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-22K16572
[Journal Article] Impact of Chronic Obstructive Pulmonary Disease on the Long-term Prognosis of Patients Undergoing Lobectomy for Non-small-cell Lung Cancer: A Propensity Score-matched Analysis2023
- Author(s)
  MATSUDO KYOTO、TAKENAKA TOMOYOSHI、HASHINOKUCHI ASATO、NAGANO TAICHI、KINOSHITA FUMIHIKO、TAKAMORI SHINKICHI、AKAMINE TAKAKI、KOHNO MIKIHIRO、MIURA NAOKO、YOSHIZUMI TOMOHARU
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 11 Pages: 5215-5222
- DOI
  10.21873/anticanres.16723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16572
[Journal Article] Skeletal muscle area predicts the outcomes of non-small-cell lung cancer after trimodality therapy2023
- Author(s)
  Watanabe Kenji、Kinoshita Fumihiko、Takenaka Tomoyoshi、Nagano Taichi、Oku Yuka、Kosai Keisuke、Ono Yuki、Haratake Naoki、Kohno Mikihiro、Kamitani Takeshi、Yoshitake Tadamasa、Okamoto Tatsuro、Shimokawa Mototsugu、Ishigami Kousei、Yoshizumi Tomoharu
- Journal Title
  
  Interdisciplinary CardioVascular and Thoracic Surgery
  
  Volume: 36 Issue: 2
- DOI
  10.1093/icvts/ivad020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16572
[Journal Article] Is radical local therapy effective in postoperative recurrent <scp><i>EGFR</i></scp>‐mutated non‐small cell lung cancer?2023
- Author(s)
  Takenaka Tomoyoshi、Yano Tokujiro、Yamazaki Koji、Okamoto Tatsuro、Hamatake Motoharu、Takamori Shinkichi、Kohno Mikihiro、Miura Naoko、Shimokawa Mototsugu、Yoshizumi Tomoharu、Kyushu University Lung Surgery Study Group
- Journal Title
  
  Thoracic Cancer
  
  Volume: 14 Issue: 18 Pages: 1660-1667
- DOI
  10.1111/1759-7714.14911
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16572
[Journal Article] Prognostic Impact of C-Reactive Protein-to-Lymphocyte Ratio in Non-small Cell Lung Cancer: A Propensity Score-Matching Analysis2023
- Author(s)
  Nagano Taichi、Kinoshita Fumihiko、Hashinokuchi Asato、Matsudo Kyoto、Watanabe Kenji、Takamori Shinkichi、Kohno Mikihiro、Miura Naoko、Shimokawa Mototsugu、Takenaka Tomoyoshi、Yoshizumi Tomoharu
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 30 Issue: 6 Pages: 3781-3788
- DOI
  10.1245/s10434-023-13250-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16572
[Journal Article] Defining and targeting tumor-associated macrophages in malignant mesothelioma2023
- Author(s)
  Wu Licun、Kohno Mikihiro、Murakami Junichi、Zia Amin、Allen Jonathan、Yun Hana、Chan Meilin、Baciu Cristina、Liu Mingyao、Serre-Beinier Veronique、De Palma Michele、Felley-Bosco Emanuela、Yeung Jonathan、Pugh Trevor J.、de Perrot Marc
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 9
- DOI
  10.1073/pnas.2210836120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16572
[Journal Article] Clinical significance of the combination of preoperative SUVmax and CEA in patients with clinical stage IA lung adenocarcinoma2022
- Author(s)
  Hashinokuchi Asato、Haratake Naoki、Takenaka Tomoyoshi、Matsudo Kyoto、Nagano Taichi、Watanabe Kenji、Kosai Keisuke、Oku Yuka、Ono Yuki、Takamori Shinkichi、Kohno Mikihiro、Baba Shingo、Ishigami Kousei、Yoshizumi Tomoharu
- Journal Title
  
  Thoracic Cancer
  
  Volume: 13 Issue: 18 Pages: 2624-2632
- DOI
  10.1111/1759-7714.14599
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16572
[Journal Article] Relationship between consolidation tumor ratio and tumor‐infiltrating lymphocytes in small‐sized lung adenocarcinoma2022
- Author(s)
  Ono Yuki、Tagawa Tetsuzo、Kinoshita Fumihiko、Haratake Naoki、Takada Kazuki、Kohno Mikihiro、Takenaka Tomoyoshi、Kamitani Takeshi、Shimokawa Mototsugu、Oda Yoshinao、Mori Masaki、Yoshizumi Tomoharu
- Journal Title
  
  Thoracic Cancer
  
  Volume: 13 Issue: 15 Pages: 2134-2141
- DOI
  10.1111/1759-7714.14524
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16572
[Presentation] 肺腺癌におけるSLC38A7の発現と生物学的・臨床的意義の検討2025
- Author(s)
  橋之口朝仁, 德永貴之, 溝田和弘, バッスィジャコモ, 松堂響人, 木下郁彦, 赤嶺貴紀, 河野幹寛原武直紀, 竹中朋祐, 吉住朋晴
- Organizer
  第125回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23K08322
[Presentation] M2マクロファージを標的とした特発性肺線維症合併肺癌の新規治療戦略の開発2025
- Author(s)
  河野幹寛
- Organizer
  第125回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-24K12016
[Presentation] 代謝経路の網羅的解析（iMPAQT法）を用いた胸膜中皮腫の新たな治療標的の探索2025
- Author(s)
  徳永貴之、田川哲三、河野幹寛、竹中朋祐
- Organizer
  第４２回日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-24K12023

1. 竹中朋祐 (20645361)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. 山崎元彦 (30772032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 石川浩志 (90377151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大橋瑠子 (20447600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 若井俊文 (50372470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 奥田修二郎 (00512310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 島田能史 (20706460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 後藤達哉 (20899512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 土田正則 (60293221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高森信吉 (20839542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 岡本龍郎 (80568626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 坪内和哉 (60961927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 橋迫美貴子 (70774678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 吉住朋晴 (80363373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 田川哲三 (90419557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 山崎宏司 (60404068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 高橋純一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 三森功士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kohno Mikihiro 河野 幹寛

KOHNO Mikihiro 河野 幹寛

Research Projects

Research Products

Co-Researchers

Overcoming acute exacerbation of interstitial lung diseases and progression of lung cancer by M2 macrophage inhibitionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

次世代プロテオミクスとグルタミン代謝に着目した胸膜中皮腫に対する新規免疫代謝療法

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

放射線・病理画像テクスチャ解析を用いた肺癌の腫瘍遺伝子変異量予測モデルの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺扁平上皮癌に対する新規グルタミントランスポーター阻害療法の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel immunotherapy targeting pleural macrophage subsets in malignant pleural mesotheliomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Comparison of radiological and pathological tumor sizes in resected non-small cell lung cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Granzyme B (GZMB)-Positive Tumor-Infiltrating Lymphocytes in Lung Adenocarcinoma: Significance as a Prognostic Factor and Association with Immunosuppressive Proteins2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transducin Beta-Like 2 is a Potential Driver Gene that Adapts to Endoplasmic Reticulum Stress to Promote Tumor Growth of Lung Adenocarcinoma.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of Chronic Obstructive Pulmonary Disease on the Long-term Prognosis of Patients Undergoing Lobectomy for Non-small-cell Lung Cancer: A Propensity Score-matched Analysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Skeletal muscle area predicts the outcomes of non-small-cell lung cancer after trimodality therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Is radical local therapy effective in postoperative recurrent <scp><i>EGFR</i></scp>‐mutated non‐small cell lung cancer?2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic Impact of C-Reactive Protein-to-Lymphocyte Ratio in Non-small Cell Lung Cancer: A Propensity Score-Matching Analysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Defining and targeting tumor-associated macrophages in malignant mesothelioma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical significance of the combination of preoperative SUVmax and CEA in patients with clinical stage IA lung adenocarcinoma2022

Author(s)

Journal Title

DOI

Data Source

Kohno Mikihiro 河野幹寛

KOHNO Mikihiro 河野幹寛