Wakai Toshifumi 若井俊文

… Alternative Names

Researcher Number	50372470
Other IDs
Affiliation (Current)	2019: 新潟大学, 医歯学系, 教授
Affiliation (based on the past Project Information) *help	2012 – 2019: 新潟大学, 医歯学系, 教授 2009 – 2011: 新潟大学, 医歯学総合病院, 講師 2009: Niigata University, 医歯学総合病院, 助教 2007: Niigata University, Medical and Dental Hospital, Assistant Professor 2005 – 2006: Niigata University, Medical and Dental Hospital, Fellow, 医歯学総合病院, 医員 2004: Niigata University, Medical and Dental Hospital, Assistant, 医歯学総合病院, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / 消化器外科学 / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Human pathology / 消化器外科学 / Public health/Health science / Hygiene / Gastroenterology … More
Keywords	Principal Investigator 胆道外科学 / 胆管癌 / p53-binding protein 1 / 上皮内癌 / Ampullary carcinoma / Metastasis / Lymph node metastasis / Micrometastasis / Cytokeratin / Immunohistochemistry … More Except Principal Investigator 大腸癌 / 免疫組織化学 / 脂質メディエーター / スフィンゴシン-1-リン酸 / 薬剤耐性 / 胃癌 / 食道癌 / 炎症性発癌 / DNA二重鎖切断 / リンパ節転移 / 膵癌 / 胆道外科学 / 胆嚢癌 / リンパ管侵襲 / 食道扁平上皮癌 / 潰瘍性大腸炎 / DNA損傷応答 / 肝がん / γH2AX / 食道外科学 / NQO1 / Nrf2 / p62 / 簇出 / 免疫染色 / 化学療法 / 肝転移 / スフィンゴシンキナーゼ1型 / 肝細胞癌 / 発癌メカニズム / 遺伝子解析 / 発癌 / S1P / 薬物療法抵抗性 / 乳癌 / 治療 / 肝内進展様式 / 静脈侵襲 / モノクローナル抗体 / 肝切除術 / 癌の転移 / 根治手術 / 疫学 / 国際保健学 / 健康管理 / 保健医療行政 / 地域保健 / 集団検診 / 医療情報学 / 中国疫学調査 / リスク因子 / 窒素化合物 / ロジスティック回帰分析 / ホットスポット分析 / 腺癌 / 条件付きロジスティック回帰分析 / マッチングデータ / 環境因子 / 喫煙 / 飲酒 / 扁平上皮癌 / dysplasia / 胆嚢がん / スクリーニング / 特異蛋白 / 質量分析 / 腫瘍マーカー / 特異蛋白質 / 国際情報交換 / チリ / プロテオミクス解析 / lymph node ratio / リンパ節転移個数 / ソラフェニブ / 分子標的薬 / TGF-beta / sorafenib / hepatocellular carcinoma / drug resistance / 肝芽腫 / CEACAM / 接着因子 / CEACAM6 / CEACAM1 / 病期 / 遠隔転移 / 大腸癌の発生 / 腺腫の癌化 / 鋸歯状病変 / DNA損傷修復応答 / 蛍光二重免疫染色 / 大腸鋸歯状病変 / SSA/P / 消化管間質腫瘍 / 術前補助化学療法 / 酸化ストレス / 術前化学療法 / 治療抵抗性 / 抗癌剤耐性 / KRAS / Keap1 / 粘膜下層浸潤癌 / 内視鏡的粘膜切除術 / 大腸粘膜下層浸潤癌 / HE染色 / CAM5.2モノクローナル抗体 / 5-ALA / 光線力学診断 / アミノレブリン酸 / PEPT-1 / PEPT-2 / 増殖能 / アポトーシス / 細胞増殖活性 / Ki-67 / TUNEL / AE1/AE3染色 / 微小転移 / 肝内微小転移 / 抗サイトケラチン抗体 / 抗サイトケラチン20抗体 / 生存分析 / colorectal carcinoma / liver metastasis / micrometastasis / hepatic micrometastasis / immunohistochemistry / anticytokeratin antibody / surgery / prognosis / カルニチン / 静脈栄養 / 脂肪乳剤 / 術後回復 / CRP / 経腸栄養 / 乳び胸 / 低脂肪経腸栄養剤 / タンパク代謝 / インスリン抵抗性 / Rapid turnover protein / 末梢静脈栄養 / RTP / RBP / スフィンゴシンキナーゼ / リンパ管新生 / リピドミクス解析 / スフィンゴシンキナーゼ１型 / エクソソーム / シスプラチン / 消化器内科 / 肝臓学 / リンパ行性進展 / 免疫組織化学染色 / pSphK1 / オートファジー / KEAP1 / リン酸化p62 / 腫瘍増殖能亢進 / 抗癌剤耐性獲得 / HCV / de novo癌 / 遺伝子関連タンパク / 発生メカニズム / アクチビン2型受容体 / マイクロサテライト不安定 / Hypermutation / 次世代シークエンサー / CRISPR/Cas9 / アクチビン受容体 / 相同組み換え修復 / BRCA / 遺伝子変異 / スフィンゴシン1リン酸 / 炎症性腸疾患 / 大腸癌肝転移 / 肝臓外科学 / 薬物療法効果予測 / マクロファージ遊走阻止因子 / 腫瘍関連マクロファージ / 腫瘍微小環境 / 胆管癌 / 胆管生検試料 / 53BP1 / スフィンゴシン‐１‐リン酸 / MED12 / 転写メディエーター / がんゲノム / データベース / 精密医療 / スフィンゴシン‐1-リン酸 / 腫瘍免疫微小環境 / 卵巣癌 / 直腸間膜リンパ節 / 直腸浸潤 / 門脈 / HER2陽性胃癌 / 抗HER2療法 / ERBB2 / 癌遺伝子解析パネル / TGF-β / SMAD4 / 脈管侵襲 / スフィンゴ脂質 / 抗がん剤耐性 / 相同組換え修復 / 癌代謝 / トリプルネガティブ乳癌 Less

乳癌免疫微小環境における脂質メディエーター分子の役割解明と治療応用を目指した研究Ongoing
- Principal Investigator
  
  永橋昌幸
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Niigata University
卵巣癌肝転移における直腸間膜リンパ節転移を経由した新たな転移経路の解明Ongoing
- Principal Investigator
  
  中野雅人
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
HER2陽性胃癌における遺伝子異常の包括的評価と臨床的意義の解明Ongoing
- Principal Investigator
  
  臼井賢司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Elucidation of the interaction between human commensal bacterial flora and host genetic alterations in the digestive tractPrincipal InvestigatorOngoing
- Principal Investigator
  
  若井俊文
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Niigata University
がんゲノム医療実現化に向けた高次元データ解析基盤構築Ongoing
- Principal Investigator
  
  奥田修二郎
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 62:Applied informatics and related fields
- Research Institution
  Niigata University
発癌の分子メカニズムの違いに着目した大腸癌TGF-βシグナル伝達経路の新たな分類Ongoing
- Principal Investigator
  
  島田能史
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
肝細胞癌の脈管侵襲における脂質メディエーター分子機構の解明と臨床的意義Ongoing
- Principal Investigator
  
  廣瀬雄己
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Clinical significance of defective DNA double-strand break repair pathway in gastric cancerOngoing
- Principal Investigator
  
  堅田朋大
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Mechanisms of cancer metabolism and drug resistance regulated by S1P in triple negative breast cancerOngoing
- Principal Investigator
  
  永橋昌幸
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Niigata University
大腸de novo癌の発生分子メカニズムの解明Ongoing
- Principal Investigator
  
  味岡洋一
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Niigata University
胃癌におけるアクチビン受容体変異による新規シグナル伝達機構の解明及び臨床的意義Ongoing
- Principal Investigator
  
  油座築
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
胃癌におけるBRCA1/2遺伝子変異解析およびタンパク質発現とその臨床的意義Ongoing
- Principal Investigator
  
  滝沢一泰
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
潰瘍性大腸炎関連大腸癌における脂質メディエーターを介した新たな発癌機構の解明Ongoing
- Principal Investigator
  
  亀山仁史
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
大腸癌肝転移における抗酸化ストレス蛋白質発現の臨床的意義と抗癌剤耐性機序の解明Ongoing
- Principal Investigator
  
  中野麻恵
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
腫瘍関連マクロファージを介した膵癌の腫瘍微小環境形成機序の解明および臨床的意義Ongoing
- Principal Investigator
  
  高野可赴
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
早期DNA損傷修復機構に基づく胆管生検試料における確証的な良悪性判定評価法の確立Ongoing
- Principal Investigator
  
  石川博補
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
脂質メディエーター産生酵素の膵癌微小環境形成における役割と臨床的意義Ongoing
- Principal Investigator
  
  中島真人
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
The mechanism of exosome-mediated drug resistance in hepatoma cells
- Principal Investigator
  
  Yasunobu MATSUDA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  消化器内科学
- Research Institution
  Niigata University
Clinical significance of sphingosine-1-phosphate and sphingosine kinase 1 in lymphatic spread of esophageal cancer
- Principal Investigator
  
  Ichikawa Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  消化器外科学
- Research Institution
  Niigata University
Elucidation of molecular mechanism through autophagy in carcinogenesis of hepatocellular carcinoma
- Principal Investigator
  
  Sakata Jun
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  消化器外科学
- Research Institution
  Niigata University
Elucidation of a novel cell signaling mechanism by lipid mediators and bile acids in biliary diseasesPrincipal Investigator
- Principal Investigator
  
  WAKAI TOSHIFUMI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  消化器外科学
- Research Institution
  Niigata University
Serum carnitine kinetics by administration of fat emulsion at the perioperative period and effect of intravenous administration of L-carnitine
- Principal Investigator
  
  Koyama Yu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Niigata University
Clinical Significance and elucidation of molecular regulation mechanism of lipid mediators in invasion and metastatic ability of gastric cancer
- Principal Investigator
  
  Hanyu Takaaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Elucidation of molecular mechanism of lipid mediator involved in metastatic ability of biliary tract cancer / pancreatic cancer and clinical applicationPrincipal Investigator
- Principal Investigator
  
  WAKAI TOSHIFUMI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
The role of MED12 expression in molecular mechanism of drug resistance of colorectal cancer
- Principal Investigator
  
  Yoshifumi Shimada
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Significance of DNA damage response in histogenesis of colorectal carcinoma
- Principal Investigator
  
  AJIOKA Yoichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Niigata University
Analysis of gene expression involved in the prognosis and occurrence site of gastrointestinal stromal tumors
- Principal Investigator
  
  ISHIKAWA Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Oxidative stress signaling as the molecular mechanism of chemo-resistance in esophageal cancer
- Principal Investigator
  
  KOSUGI Shin-ichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Elucidation of the mechanism of drug resistance in colorectal cancer by p62-Keap 1-Nrf2 pathway
- Principal Investigator
  
  KAMEYAMA Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Biological evaluation and significance of tumor budding using fluorescence immunohistochemistry in pT1b colorectal cancer
- Principal Investigator
  
  NOGAMI Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Prediction of Chemotherapy Response to Pancreatic Cancer Using Photodynamic diagnosis
- Principal Investigator
  
  MINAGAWA Masahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Assessment of proliferation and apoptotic rate of tumor budding cells in pancreatic ductal adenocarcinoma.
- Principal Investigator
  
  Takizawa Kazuyasu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Molecular Analysis of Cytokine-mediated Sorafenib Resistance
- Principal Investigator
  
  MATSUDA YASUNOBU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinomaPrincipal Investigator
- Principal Investigator
  
  WAKAI Toshifumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Molecular Analysis of CEACAM Family in Hepatoblastoma
- Principal Investigator
  
  NAKAYA KENGO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Niigata University
Significance of DNA damage response in cancerization in ulcerative colitis
- Principal Investigator
  
  AJIOKA Yoichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Niigata University
SEARCHING OF SPECIFIC PROTEINS PRODUCED IN GALLBLADDER CANCER TISSUES FOR THE EARLY DETECTION OF THE CANCER
- Principal Investigator
  
  TSUCHIYA Yasuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Niigata University of Health and Welfare
A Proposal of New Nodal Classification in Gallbladder Cancer
- Principal Investigator
  
  SAKATA Jun
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Epidemiological study for identifying risk factors of esophageal adenocarcinoma in north China.
- Principal Investigator
  
  AKAZAWA Kohei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Niigata University
Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinomaPrincipal Investigator
- Principal Investigator
  
  WAKAI Toshifumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Mode of Hepatic Spread from Gallbladder Carcinoma : An Immunohistochemical Analysis of 42 Hepatectomized Specimens
- Principal Investigator
  
  SHIRAI Yoshio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
The mechanism and clinical significance of loss of CEACAM1 expression in hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  WAKAI Toshifumi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Clinical significance of lymph node micrometastasis in ampullary carcinomaPrincipal Investigator
- Principal Investigator
  
  WAKAI Toshifumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Colorectal Carcinoma liver Metastases : Immunohistochemical Detection of Hepatic Micrometastases Using Monoclonal Anticytokeratin Antibody
- Principal Investigator
  
  SHIRAI Yoshio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  NIIGATA UNIVERSITY

[Journal Article] Hyperbilirubinemia predicts the infectious complications after esophagectomy for esophageal cancer2019
- Author(s)
  Muneoka Yusuke、Ichikawa Hiroshi、Kosugi Shin-ichi、Hanyu Takaaki、Ishikawa Takashi、Kano Yosuke、Shimada Yoshifumi、Nagahashi Masayuki、Sakata Jun、Kobayashi Takashi、Kameyama Hitoshi、Akazawa Kohei、Wakai Toshifumi
- Journal Title
  
  Annals of Medicine and Surgery
  
  Volume: 39 Pages: 16-21
- DOI
  10.1016/j.amsu.2019.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04093, KAKENHI-PROJECT-16K10491
[Journal Article] Phospho-Sphingosine Kinase 1 Expression in Lymphatic Spread of Esophageal Squamous Cell Carcinoma2019
- Author(s)
  Nemoto Mariko、Ichikawa Hiroshi、Nagahashi Masayuki、Hanyu Takaaki、Ishikawa Takashi、Kano Yosuke、Muneoka Yusuke、Wakai Toshifumi
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 234 Pages: 123-131
- DOI
  10.1016/j.jss.2018.09.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10491
[Journal Article] SMAD4 alteration associates with invasive-front pathological markers and poor prognosis in colorectal cancer2019
- Author(s)
  Oyanagi H, Shimada Y, Nagahashi M, Ichikawa H, Tajima Y, Abe K, Nakano M, Kameyama H, Takii Y, Kawasaki T, Homma KI, Ling Y, Okuda S, Takabe K, Wakai T.
- Journal Title
  
  Histopathology
  
  Volume: 74 Pages: 873-882
- DOI
  10.1111/his.13805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08612
[Journal Article] Robot-assisted laparoscopic radical cystectomy is a safe and effective procedure for patients with bladder cancer compared to laparoscopic and open surgery: Perioperative outcomes of a single-center experience.2019
- Author(s)
  Hotta S, Shimada Y, Nakano M, Yamada S, Abe K, Oyanagi H, Yagi R, Tajima Y, Nakano M, Kameyama H, Nagahashi M, Sakata J, Kobayashi T, Wakai T.
- Journal Title
  
  Asian J Surg
  
  Volume: 印刷中 Pages: 189-196
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10624, KAKENHI-PROJECT-15K10648
[Journal Article] Pathogenic Germline BRCA1/2 Mutations and Familial Predisposition to Gastric Cancer2018
- Author(s)
  Ichikawa H, Wakai T, Nagahashi M, Shimada Y, Hanyu T, Kano Y, Muneoka Y, Ishikawa T, Takizawa K, Tajima Y, Sakata J, Kobayashi T, Kameyama H, Yabusaki H, Nakagawa S, Sato N, Kawasaki T, Homma K, Okuda S, Lyle S, Takabe K
- Journal Title
  
  JCO precision oncology
  
  Volume: 5 Pages: 1-8
- DOI
  10.1200/jco.2018.36.15_suppl.e13618
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10580
[Journal Article] Expression of phosphorylated sphingosine kinase 1 is associated with diffuse type and lymphatic invasion in human gastric cancer.2018
- Author(s)
  Hanyu T, Nagahashi M, Ichikawa H, Ishikawa T, Kobayashi T, Wakai T.
- Journal Title
  
  Surgery
  
  Volume: [Epub ahead of print]
- DOI
  10.1016/j.surg.2017.11.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10087
[Journal Article] Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis2018
- Author(s)
  Hirose Y, Nagahashi M, Katsuta E, Yuza K, Miura K, Sakata J, Kobayashi T, Ichikawa H, Shimada Y, Kameyama H, McDonald KA, Takabe K, Wakai T
- Journal Title
  
  Sci Rep
  
  Volume: 8 Pages: 10814-10814
- DOI
  10.1038/s41598-018-29144-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Journal Article] Different Roles of Sphingosine Kinase 1 and 2 in Pancreatic Cancer Progression.2018
- Author(s)
  Yuza Kizuki、Nakajima Masato、Nagahashi Masayuki、Tsuchida Junko、Hirose Yuki、Miura Kohei、Tajima Yosuke、Abe Manabu、Sakimura Kenji、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  J Surg Res
  
  Volume: 232 Pages: 186-194
- DOI
  10.1016/j.jss.2018.06.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-17K10692
[Journal Article] Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer.2018
- Author(s)
  Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Takabe K, Wakai T.
- Journal Title
  
  Journal of surgical research
  
  Volume: 231 Pages: 323-330
- DOI
  10.1016/j.jss.2018.05.085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10624
[Journal Article] Genomic characterization of colitis-associated colorectal cancer.2018
- Author(s)
  Kameyama H, Nagahashi M, Shimada Y, Tajima Y, Ichikawa H, Nakano M, Sakata J, Kobayashi T, Narayanan S, Takabe K, Wakai T.
- Journal Title
  
  World journal of surgical oncology
  
  Volume: 16 Pages: 121-121
- DOI
  10.1186/s12957-018-1428-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10624
[Journal Article] Next generation sequencing-based gene panel tests for the management of solid tumors.2018
- Author(s)
  Nagahashi M, Shimada Y, Ichikawa H, Kameyama H, Takabe K, Okuda S, Wakai T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 110 Pages: 6-15
- DOI
  10.1111/cas.13837
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04123
[Journal Article] The role of sphingosine-1-phosphate in inflammation and cancer progression2018
- Author(s)
  Nagahashi Masayuki、Abe Manabu、Sakimura Kenji、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Pages: 3671-3678
- DOI
  10.1111/cas.13802
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Journal Article] Feasibility of restorative proctocolectomy in patients with ulcerative colitis-associated lower rectal cancer: A retrospective study.2018
- Author(s)
  Hotta S, Shimada Y, Nakano M, Yamada S, Abe K, Oyanagi H, Yagi R, Tajima Y, Nakano M, Kameyama H, Nagahashi M, Sakata J, Kobayashi T, Wakai T.
- Journal Title
  
  Asian Journal of Surgery
  
  Volume: 印刷中
- DOI
  10.1016/j.asjsur.2018.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10130
[Journal Article] Hypermutation and microsatellite instability in gastrointestinal cancers2017
- Author(s)
  Yuza Kizuki、Nagahashi Masayuki、Watanabe Satoshi、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 112103-112115
- DOI
  10.18632/oncotarget.22783
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10579
[Journal Article] Utility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer2017
- Author(s)
  Shimada Y, Yagi R, Kameyama H, Nagahashi M, Ichikawa H, Tajima Y, Okamura T, Nakano M, Nakano M, Sato Y, Matsuzawa T, Sakata J, Kobayashi T, Nogami H, Maruyama S, Takii Y, Kawasaki T, Homma KI, Izutsu H, Kodama K, Ring JE, Protopopov A, Lyle S, Okuda S, Akazawa K, Wakai T.
- Journal Title
  
  Human Pathology
  
  Volume: 66 Pages: 1-9
- DOI
  10.1016/j.humpath.2017.02.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10130
[Journal Article] Relevance of Dissection of the Posterior Superior Pancreaticoduodenal Lymph Nodes in Gallbladder Carcinoma.2017
- Author(s)
  Sakata J，Kobayashi T，Tajima Y，Ohashi T，Hirose Y，Takano K，Takizawa K，Miura K，Wakai T
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 24 Pages: 2474-2481
- DOI
  10.1245/s10434-017-5939-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15610
[Journal Article] The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications2017
- Author(s)
  Nakajima M, Nagahashi M, Rashid OM, Takabe K, Wakai T.
- Journal Title
  
  Tumor Biology
  
  Volume: 39 Pages: 1010428-1010428
- DOI
  10.1177/1010428317699133
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610, KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15H05676
[Journal Article] 癌と宿主におけるスフィンゴシン-1-リン酸の役割2017
- Author(s)
  永橋　昌幸，若井　俊文
- Journal Title
  
  BIO Clinica
  
  Volume: 32 Pages: 397-404
- Data Source
  KAKENHI-PROJECT-15H04927
[Journal Article] Prognostic heterogeneity of the seventh edition of UICC Stage III gallbladder carcinoma: Which patients benefit from surgical resection?2017
- Author(s)
  Sakata J, Kobayashi T, Ohashi T, Hirose Y, Takano K, Takizawa K, Miura K, Ishikawa H, Toge K, Yuza K, Soma D, Ando T, Wakai T
- Journal Title
  
  Eur J Surg Oncol.
  
  Volume: 43 Pages: 780-787
- DOI
  10.1016/j.ejso.2017.01.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-16K15610
[Journal Article] Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer2017
- Author(s)
  Shimada Y, Kameyama H, Nagahashi M, Ichikawa H, Muneoka Y, Yagi R, Tajima Y, Okamura T, Nakano M, Sakata J, Kobayashi T, Nogami H, Maruyama S, Takii Y, Hayashida T, Takaishi H, Kitagawa Y, Oki E, Konishi T, Ishida F, Kudo SE, Ring JE, Protopopov A, Lyle S, Ling Y, Okuda S, Ishikawa T, Akazawa K, Takabe K, Wakai T.
- Journal Title
  
  Oncotarget
  
  Volume: 24 Pages: 93567-93579
- DOI
  10.18632/oncotarget.20510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10130
[Journal Article] Intravenous Carnitine Administration in Addition to Parenteral Nutrition with Lipid Emulsion may Decrease the Inflammatory Reaction in Postoperative Surgical Patients.2017
- Author(s)
  KoyamaY, Moro K, Nakano M, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Hanyu T, Shimada Y, Jun Sakata J, Kameyama H, Kobayashi T, Wakai T.
- Journal Title
  
  Journal of Clinical Medicine Research
  
  Volume: 9 Pages: 831-837
- DOI
  10.14740/jocmr3113w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10047
[Journal Article] Association between poorly differentiated clusters and efficacy of 5-fluorouracil-based adjuvant chemotherapy in stage III colorectal cancer2017
- Author(s)
  Tajima Y, Shimada Y, Kameyama H, Yagi R, Okamura T, Kobayashi T, Kosugi SI, Wakai T.
- Journal Title
  
  Japan Journal of Clinical Oncology
  
  Volume: 47 Pages: 313-320
- DOI
  10.1093/jjco/hyw209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10130
[Journal Article] Clinical significance of NQO1 expression in patients with advanced KRAS wild colorectal cancer2017
- Author(s)
  Hitoshi Kameyama, Yuki Hirose, Yasunobu Matsuda, Masayuki Nagahashi, Hiroshi Ichikawa, You Sato, Saki Yamada, Shinnosuke Hotta, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Toshifumi Wakai
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462006
[Journal Article] 肝細胞癌発癌過程におけるオートファジーを介した分子制御機構の解明2017
- Author(s)
  坂田純、廣瀬雄己、齊藤哲也、小松雅明、若井俊文
- Journal Title
  
  Medical Science Digest
  
  Volume: 43 Pages: 331-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10565
[Journal Article] 癌と宿主におけるスフィンゴシン-1-リン酸の役割2017
- Author(s)
  永橋昌幸、若井俊文
- Journal Title
  
  BIO Clinica
  
  Volume: 32 Pages: 397-404
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K15610
[Journal Article] Prognostic factors after imatinib secondary resistance: survival analysis in patients with unresectable and metastatic gastrointestinal stromal tumors.2016
- Author(s)
  Kanda T, Ishikawa T, Kosugi S-I, Ueki K, Naito T, Wakai T, Hirota S.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 21 Pages: 295-301
- DOI
  10.1007/s10147-015-0903-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05166, KAKENHI-PROJECT-26461970
[Journal Article] The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases2016
- Author(s)
  Nagahashi M, Yuza K, Hirose Y, Nakajima M, Ramanathan R, Hait NC, Hylemon PB, Zhou H, Takabe K, Wakai T.
- Journal Title
  
  J Lipid Res
  
  Volume: 57 Pages: 1636-1643
- DOI
  10.1194/jlr.r069286
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471, KAKENHI-PROJECT-16K15610
[Journal Article] Interstitial fluid sphingosine-1-phosphate in murine mammary gland and cancer and human breast tissue and cancer determined by novel methods2016
- Author(s)
  Nagahashi M, Yamada A, Miyazaki H, Allegood JC, Tsuchida J, Aoyagi T, Huang WC, Terracina KP, Adams BJ, Rashid OM, Milstien S, Wakai T, Spiegel S, Takabe K.
- Journal Title
  
  J Mammary Gland Biol Neoplasia
  
  Volume: 21 Pages: 9-17
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15H05676
[Journal Article] Clinical significance of MED12 expression in colorectal cancer.2016
- Author(s)
  Shimada Y, Tajima Y, Kameyama H, Yagi R, Okamura T, Hirose Y, Sakata J, Kobayashi T, Matsuda Y, Ajioka Y, Kosugi SI, Wakai T
- Journal Title
  
  Int J Clin Exp Pathol.
  
  Volume: 9 Pages: 6937-44
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10130
[Journal Article] 脂質メディエーターを介した胆汁酸シグナル伝達系の役割2016
- Author(s)
  永橋昌幸, 大橋拓, 滝沢一泰, 坂田純, 小林隆, 若井俊文
- Journal Title
  
  胆道
  
  Volume: 30 Pages: 220-227
- NAID
  130005157398
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K15610
[Journal Article] Prognostic significance of NQO1 expression in esophageal squamous cell carcinoma after preoperative chemotherapy with cisplatin and 5-fluorouracil followed by curative esophagectomy2016
- Author(s)
  Ichikawa H, Kosugi S, Hirose Y, Matsuda Y, Ishikawa T, Hanyu T, Usui K, Muneoka Y, Nagahashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T
- Journal Title
  
  International Journal of Clinical and Experimental Pathology
  
  Volume: 9 Pages: 7393-7401
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461971
[Journal Article] Comparison of Number Versus Ratio of Positive Lymph Nodes in the Assessment of Lymph Node Status in Extrahepatic Cholangiocarcinoma2016
- Author(s)
  Sakata J, Wakai T, Matsuda Y, Ohashi T, Hirose Y, Ichikawa H, Kobayashi T, Minagawa M, Kosugi S, Koyama Y, Akazawa K, Ajioka Y
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 23 Pages: 225-234
- DOI
  10.1245/s10434-015-4609-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04927
[Journal Article] Surgical and long-term outcomes following oesophagectomy in oesophageal cancer patients with comorbidity2016
- Author(s)
  Ichikawa H, Kosugi SI, Kanda T, Yajima K, Ishikawa T, Hanyu T, Muneoka Y, Otani T, Nagahashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T
- Journal Title
  
  International Journal of Surgery
  
  Volume: 36 Pages: 212-218
- DOI
  10.1016/j.ijsu.2016.10.041
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K10491
[Journal Article] Sphingosine-1-phosphate in the lymphatic fluid determined by novel methods2016
- Author(s)
  Nagahashi M, Yamada A, Aoyagi T, Allegood J, Wakai T, Spiegel S, Takabe K
- Journal Title
  
  Heliyon
  
  Volume: 2
- DOI
  10.1016/j.heliyon.2016.e00219
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K15610, KAKENHI-PROJECT-16K19055
[Journal Article] Low fat-containing elemental formula is effective for postoperative recovery and potentially useful for preventing chyle leak during postoperative early enteral nutrition after esophagectomy2016
- Author(s)
  Moro K, Koyama Y, Kosugi SI, Ishikawa T, Ichikawa H, Hanyu T, Miura K, Nagahashi M, Nakajima M, Tatsuda K, Tsuchida J, Toshikawa C, Ikarashi M, Shimada Y, Sakata J, Kobayashi T, Kameyama H, Wakai T
- Journal Title
  
  Clinical Nutrition
  
  Volume: 35 Pages: 1423-1428
- DOI
  10.1016/j.clnu.2016.03.018
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10047, KAKENHI-PROJECT-16K10491
[Journal Article] Tumor Budding Detection by Immunohistochemical Staining is Not Superior to Hematoxylin and Eosin Staining for Predicting Lymph Node Metastasis in pT1 Colorectal Cancer.2016
- Author(s)
  Takuma Okamura
- Journal Title
  
  Diseases of the colon and rectum
  
  Volume: 59 Pages: 396-402
- DOI
  10.1097/dcr.0000000000000567
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462007
[Journal Article] Prognostic significance of NQO1 expression in esophageal squamous cell carcinoma after preoperative chemotherapy with cisplatin and 5-fluorouracil followed by curative esophagectomy2016
- Author(s)
  Ichikawa H, Kosugi S, Hirose Y, Matsuda Y, Ishikawa T, Hanyu T, Usui K, Muneoka Y, Nagahashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T
- Journal Title
  
  International Journal of Clinical and Experimental Pathology
  
  Volume: 9 Pages: 7393-7401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10491
[Journal Article] Surgical resection of recurrent gastrointestinal stromal tumor after interruption of long-term nilotinib therapy.2016
- Author(s)
  Sugase T, Takahashi T, Ishikawa T, Ichikawa H, Kanda T, Hirota S, Nakajima K, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Takiguchi S, Wakai T, Mori M, Doki Y.
- Journal Title
  
  Surg Case Rep.
  
  Volume: 2 Pages: 137-137
- DOI
  10.1186/s40792-016-0266-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461970
[Journal Article] Resolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancer2016
- Author(s)
  Moro K, Nagahashi M, Ramanathan R, Takabe K, Wakai T.
- Journal Title
  
  World J Clin Cases
  
  Volume: 4 Pages: 155-164
- DOI
  10.12998/wjcc.v4.i7.155
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471
[Journal Article] Nagahashi M, Matsuda Y, Moro K, Tsuchida J, Soma D, Hirose Y, Kobayashi T, Kosugi SI, Takabe K, Komatsu M, Wakai T Nagahashi M, Yamada A, Aoyagi T, Allegood J, Wakai T, Spiegel S, Takabe K2016
- Author(s)
  Nagahashi M, Matsuda Y, Moro K, Tsuchida J, Soma D, Hirose Y, Kobayashi T, Kosugi SI, Takabe K, Komatsu M, Wakai T
- Journal Title
  
  Surg Today
  
  Volume: 印刷中 Pages: 995-1005
- DOI
  10.1007/s00595-015-1270-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471, KAKENHI-PROJECT-16K15610
[Journal Article] Valproic acid overcomes transforming growth factor-β-mediated sorafenib resistance in hepatocellular carcinoma2014
- Author(s)
  Yasunobu Matsuda, Toshifumi Wakai, Masayuki Kubota, Mami Osawa, Yuki Hirose, Jun Sakata, Takashi Kobayashi, Shun Fujimaki, Masaaki Takamura, Satoshi Yamagiwa, Yutaka Aoyagi
- Journal Title
  
  International Journal of Clinical & Experimental Pathology
  
  Volume: 7(4) Pages: 1299-1313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590962
[Journal Article] Valproic acid overcomes transforming growth factor-β-mediated sorafenib resistance in hepatocellular carcinoma.2014
- Author(s)
  Matsuda Y, Wakai T, Kubota M, Osawa M, Hirose Y, Sakata J, Kobayashi T, Fujimaki S, Takamura M, Yamagiwa S, Aoyagi Y.
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 7 (4) Pages: 1299-1313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590962
[Journal Article] Alteration of the DNA damage response in colorectal tumor progression2013
- Author(s)
  Takabayashi H, Wakai T, Ajioka Y, Korita, Yamaguchi N
- Journal Title
  
  Human Pathology
  
  Volume: 44 Pages: 1038-1046
- DOI
  10.1016/j.humpath.2012.09.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590391
[Journal Article] Risk of subsequent biliary malignancy in patients undergoing cyst excision for congenital choledochal cysts2013
- Author(s)
  Ohashi T, Wakai T, Kubota M, Matsuda Y, Arai Y, Ohyama T, Nakaya K, Okuyama N, Sakata J, Shirai Y, Ajioka Y
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Pages: 243-247
- DOI
  10.1111/j.1440-1746.2012.07260.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592693, KAKENHI-PROJECT-24659773
[Journal Article] Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma.2013
- Author(s)
  Wakai T, Shirai Y, Sakata J, Korita PV, Ajioka Y, Hatakeyama K
- Journal Title
  
  J Hepatobiliary Pancreat Sci
  
  Volume: 11 Pages: 362-369
- DOI
  10.1007/s00534-012-0539-1
- NAID
  10031168232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590391, KAKENHI-PROJECT-24592021
[Journal Article] Assessment of lymph node status in gallbladder cancer: location, number, or ratio of positive nodes2013
- Author(s)
  Shirai Y, Sakata J, Wakai T, Ohashi T, Ajioka Y, Hatakeyama K
- Journal Title
  
  World Journal of Surgical Oncology
  
  Volume: 10 Pages: 87-87
- DOI
  10.1186/1477-7819-10-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592004
[Journal Article] Heavy alcohol intake is a risk factor for esophageal squamous cell carcinoma among middle-aged Chinese men : a case-control study and simulation2013
- Author(s)
  Kumagai N, Akazawa K, Wakai T et al
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22406021
[Journal Article] Effects of rapamycin on granulation formation in response to centrally-doubled coiled stents as a tracheal substitute.2013
- Author(s)
  Kubota M, Matsuda Y, Fujimaki S, Osawa M, Wakai T, Nakaya K
- Journal Title
  
  J Pediatr Surg
  
  Volume: 48 Pages: 2416-2424
- DOI
  10.1016/j.jpedsurg.2013.08.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592693, KAKENHI-PROJECT-24659773
[Journal Article] pT_<2-3> (ss/se)胆嚢癌に対する外科切除2012
- Author(s)
  若井俊文
- Journal Title
  
  肝胆膵画像
  
  Volume: 14 Pages: 23-29
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] Assessment of lymph node status in gallbladder cancer : location, number, or ratio of positive nodes2012
- Author(s)
  Shirai Y, Sakata J, Wakai T, Ohashi T, Ajioka Y, Hatakeyama K.
- Journal Title
  
  World J Surg Oncol
  
  Volume: 10 Pages: 87-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592004
[Journal Article] Extended radical cholecystectomy for gallbladder cancer : long-term outcomes, indications and limitations2012
- Author(s)
  Shirai Y, Sakata J, Wakai T, Ohashi T, Hatakeyama K.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 18 Pages: 4736-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592004
[Journal Article] Surgical Outcomes of Minor Hepatectomy for Locally Advanced Gallbladder Carcinoma2012
- Author(s)
  Wakai T, Shirai Y, Sakata J, Tsuchiya Y, Nomura T, Hatakeyama K
- Journal Title
  
  Hepatogastroenterology
  
  Volume: (掲載確定済み) Pages: 59-59
- DOI
  10.5754/hge12097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] Extended radical cholecystectomy for gallbladder cancer : long-term outcomes, indications, and limitations2012
- Author(s)
  Shirai Y, Sakata J, Wakai T, Ohashi T, Hatakeyama K
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: (掲載確定済み)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] Regional lymphadenectomy for gallbladder cancer : rational extent, technical details, and patient outcomes2012
- Author(s)
  Shirai Y, Wakai T, Sakata J, Hatakeyama K.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 18 Pages: 2775-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592004
[Journal Article] Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling.2012
- Author(s)
  Fujimaki S, Matsuda Y, Wakai T, Sanpei A, Kubota M, Takamura M, Yamagiwa S, Yano M, Ohkoshi S, Aoyagi Y.
- Journal Title
  
  Cancer lett
  
  Volume: 319 Pages: 98-108
- DOI
  10.1155/2013/597095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590962
[Journal Article] Full-thickness cholecystectomy with limited lymphadenectomy for gallbladder cancer2012
- Author(s)
  Shirai Y, Sakata J, Wakai T, Hatakeyama K.
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 59 Pages: 1338-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592004
[Journal Article] pT2-3(ss/se)胆嚢癌に対する外科切除2012
- Author(s)
  若井俊文、白井良夫、坂田純、大橋拓、山口尚之、味岡洋一、畠山勝義
- Journal Title
  
  肝胆膵画像
  
  Volume: 14 Pages: 23-29
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] 胆嚢癌肝内進展様式とその診断2012
- Author(s)
  若井俊文、坂田純、大橋拓、井上真、白井良夫、畠山勝義
- Journal Title
  
  肝胆膵
  
  Volume: 64 Pages: 523-530
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] Regional lymphadenectomy for gallbladder cancer: rational extent, technical details, and patient outcomes2012
- Author(s)
  Shirai Y, Wakai T, Sakata J, Hatakeyama K
- Journal Title
  
  World J Gastroenterol
  
  Volume: 18(22) Pages: 2775-83
- DOI
  10.3748/wjg.v18.i22.2775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592004
[Journal Article] Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2011
- Author(s)
  Wakai T, Shirai Y, Sakata J, Korita PV, Matsuda Y, Takamura M, Ohashi R, Nagahashi M, Ajioka Y, Hatakeyama K
- Journal Title
  
  International Journal of Oncology
  
  Volume: 38 Pages: 1227-1236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590391
[Journal Article] Alcohol Consumption as a Risk Factor for Esophageal Adenocarcinoma in North China2011
- Author(s)
  Chen J, Zhang N, Ling Y, Wakai T, He Y, Wei L, Wang S, Akazawa K
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 224(1) Issue: 1 Pages: 21-27
- DOI
  10.1620/tjem.224.21
- NAID
  10028233735
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22406021
[Journal Article] p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma.2011
- Author(s)
  若井俊文、松田康伸, 他8名
- Journal Title
  
  International Journal of Oncology
  
  Volume: 38 Pages: 1227-1236
- DOI
  10.3892/ijo.2011.959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835, KAKENHI-PROJECT-21591768, KAKENHI-PROJECT-23590391
[Journal Article] 胆嚢癌2011
- Author(s)
  若井俊文
- Journal Title
  
  臨床外科
  
  Volume: 66 Pages: 1342-1347
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2011
- Author(s)
  Wakai T, Shirai Y, Sakata J, Korita PV, Matsuda Y, Takamura M, Ohashi R, Nagahashi M, Ajioka Y, Hatakeyama K
- Journal Title
  
  Int J Oncol
  
  Volume: 38(5) Pages: 1227-1236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591768
[Journal Article] 胆管癌根治切除後の胆管切離断端に遺残した上皮内癌における早期DNA損傷修復応答と局所再発との関連2010
- Author(s)
  若井俊文, 他
- Journal Title
  
  胆道
  
  Volume: 24 Pages: 667-674
- NAID
  10030361447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591768
[Journal Article] Mode of hepatic spread from gallbladder cazcinoma : an immunohistochemical analysis of 42 hepatectomized specimens2010
- Author(s)
  若井俊文, 白井良夫, ほか4名
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: Vol.34 Pages: 65-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] Mode of hepatic spread from gallbladder carcinoma : an immunohistochemical analysis of 42 hepatectomized specimens2010
- Author(s)
  若井俊文, 白井良夫, ほか4名
- Journal Title
  
  American Journal of Surgical Pathology Vol.34
  
  Pages: 65-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] 胆管癌根治切除後の胆管切離断端に遺残した上皮内癌における早期DNA損傷修復応答と局所再発との関連2010
- Author(s)
  若井俊文, 白井良夫, 坂田純, Korita V. Pavel, 味岡洋一, 畠山勝義
- Journal Title
  
  胆道
  
  Volume: 24(5) Pages: 667-674
- NAID
  10030361447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591768
[Journal Article] Mode of hepatic spread from gallbladder carcinoma American Journal of Surgical Pathology : an immunohistochemical analysis of 42 hepatectomized specimens2010
- Author(s)
  Wakai T, Shirai Y, Sakata J, Nagahashi M, Ajioka Y, Hatakeyama K
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: 34 Pages: 65-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] 進行胆嚢癌における術式選択2010
- Author(s)
  若井俊文, 白井良夫, ほか4名
- Journal Title
  
  外科治療
  
  Volume: Vol.102 Pages: 232-238
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] Effect of the interaction between the amount and duration of alcohol consumption and tobacco smoking on the risk of esophageal cancer:A case-control study2010
- Author(s)
  Chen J, Zhang N, Wakai T, Wei L, He Y, Kumagai N, Kitsu K, Wang S, Akazawa K
- Journal Title
  
  Experimental and therapeutic medicine
  
  Volume: 1(6) Pages: 991-997
- DOI
  10.3892/etm.2010.152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22406021
[Journal Article] Number of positive lymph nodes independently determines the prognosis after resection in patients with gallbladder carcinoma2010
- Author(s)
  Sakata J, Shirai Y, Wakai T, Ajioka Y, Hatakeyama K
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 17 Pages: 1831-1840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591769
[Journal Article] Tumor suppressor carcinoembryonic antigen-related cell adhesion molecule 1 potentates the anchorage-independent growth of human hepatoma HepG2 cells2007
- Author(s)
  Hokari, M, Matsuda, Y, Wakai, T, et. al.
- Journal Title
  
  Life Science 81
  
  Pages: 336-345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591504
[Journal Article] Tumor suppressor carcinoembryonic antigen-related cell adhesion molecule 1 potentates the anchorage-independent growth of human hepatoma HepG2 cells.2007
- Author(s)
  Hokari M, Matsuda Y, Wakai T, et. al.
- Journal Title
  
  Life Science 81
  
  Pages: 336-345
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591504
[Journal Article] Long-term outcomes after hepatectomy for recurrences after prior local ablation for hepatocellular carcinoma.2007
- Author(s)
  Sakata J, Shirai Y, Wakai T, et. al.
- Journal Title
  
  European Journal of Surgical Oncology
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591504
[Journal Article] Anatomic resection independently improves long-term survival in patients with T1-T2 hepatocellular carcinoma.2007
- Author(s)
  Wakai, T, Shirai, Y, Sakata, J, et. al.
- Journal Title
  
  Annals of Surgical Oncology 14
  
  Pages: 1356-1365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591504
[Journal Article] Anatomic resection independently improves long-term survival in patients with T1-T2 hepatocellular carcinoma.2007
- Author(s)
  Wakai T, Shirai Y, Sakata J, et. al.
- Journal Title
  
  Annals of Surgical Oncology 14
  
  Pages: 1356-1365
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591504
[Journal Article] Long-term outcomes after hepatectomy for recurrences after prior local ablation for hepatocellular carcinoma.2007
- Author(s)
  Sakata, J, Shirai, Y, Wakai, T, et. al.
- Journal Title
  
  European Journal of Surgical Oncology, PMID 17475439
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591504
[Journal Article] Long-term outcomes of hepatectomy vs percutaneous ablation for treatment of hepatocellular carcinoma 【less than or equal】 4 cm2006
- Author(s)
  Wakai T, Shirai Y, Suda T, Yokoyama N, Sakata J, Cruz PV, Kawai H, Matsuda Y, Watanabe M, Aoyagi Y, Hatakeyama K
- Journal Title
  
  World Journal of Gastroenterology 12・4
  
  Pages: 546-552
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Long-term outcomes of hepatectomy vs percutaneous ablation for treatment of hepatocellular carcinomas 【less than or equal】 4 cm.2006
- Author(s)
  Wakai T, Shirai Y, Suda T, Yokoyama N, Sakata J, Cruz PV, Kawai H, Matsuda Y, Watanabe M, Aoyagi Y, Hatakeyama K.
- Journal Title
  
  World Journal of Gastroenterology 12(4)
  
  Pages: 546-552
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Jaundice at presentation heralds advanced disease and poor prognosis in patients with ampullary carcinoma.2005
- Author(s)
  Yokoyama N, Shirai Y, Wakai T, Nagakura S, Akazawa K, Hatakeyama K
- Journal Title
  
  World Journal of Surgery 29・4
  
  Pages: 519-523
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Loss of carcinoembryonic antigen-related cell adhesion molecule 1 expression is an adverse prognostic factor in hepatocellular carcinoma.2005
- Author(s)
  Cruz PV, Wakai T, Shirai Y, Yokoyama N, Hatakeyama K
- Journal Title
  
  Cancer 104・2
  
  Pages: 354-360
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Peroral cholangioscopy for non-invasive papillary cholangiocarcinoma with extensive superficial ductal spread.2005
- Author(s)
  Wakai T, Shirai Y, Hatakeyama K.
- Journal Title
  
  World Journal of Gastroenterology 11(41)
  
  Pages: 6554-6556
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Loss of carcinoembryonic antigen-related cell adhesion molecule 1 expression is an adverse prognostic factor in hepatocellular carcinoma.2005
- Author(s)
  Cruz PV, Wakai t, Shirai Y, Yokoyama N, Hatakeyama K.
- Journal Title
  
  Cancer 104(2)
  
  Pages: 354-360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Jaundice at presentation heralds advanced disease and poor prognosis in patients with ampullary carcinoma.2005
- Author(s)
  Yokoyama N, Shirai Y, Wakai T, Nagakura S, Akazawa K, Hatakeyama K.
- Journal Title
  
  World Journal of Surgery 29(4)
  
  Pages: 519-523
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Impact of ductal resection margin status on long-term survival in patients undergoing resection for extrahepatic cholangiocarcinoma.2005
- Author(s)
  Wakai T, Shirai Y, Moroda T, Yokoyama N, Hatakeyama K
- Journal Title
  
  Cancer 103・6
  
  Pages: 1210-1216
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Impact of ductal resection margin status on long-term survival in patients undergoing resection for extrahepatic cholangiocarcinoma.2005
- Author(s)
  Wakai T, Shirai Y, Moroda T, Yokoyama N, Hatakeyama K.
- Journal Title
  
  Cancer 103(6)
  
  Pages: 1210-1216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Loss of carcinoembryonic antigen-related cell adhesion molecule 1 expression is an adverse prognostic factor in hepatocellular carcinoma.2005
- Author(s)
  Cruz PV, Wakai t, Shirai Y, Yokoyama N, Hatakeyama K
- Journal Title
  
  Cancer 104・2
  
  Pages: 354-360
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Peroral cholangioscopy for non-invasive papillary cholangiocarcinoma with extensive superficial ductal spread.2005
- Author(s)
  Wakai T, Shirai Y, Hatakeyama K
- Journal Title
  
  World Journal of Gastroenterology 11・41
  
  Pages: 6554-6556
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Hepatitis viral status affects the pattern of intrahepatic recurrence after resection for hepatocellular carcinoma2003
- Author(s)
  Toshifumi Wakai
- Journal Title
  
  European Journal of Surgical Oncology 29
  
  Pages: 266-271
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591390
[Journal Article] Hepatitis viral status affects the pattern of intrahepatic recurrence after resection for hepatocellular carcinoma.2003
- Author(s)
  T.Wakai
- Journal Title
  
  European Journal of Surgical Oncology Vol.29
  
  Pages: 266-271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591390
[Journal Article] Clinical significance of lymph node micrometastasis in ampullary carcinoma.
- Author(s)
  Sakata E, Shirai Y, Yokoyama N, Wakai T, Sakata J, Hatakeyama K.
- Journal Title
  
  World Journal of Surgery (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Journal Article] Clinical significance of lymph node micrometastasis in ampullary carcinoma
- Author(s)
  Sakata E, Shirai Y, Yokoyama N, Wakai T, Sakata J, Hatakeyama K
- Journal Title
  
  World Journal of Surgery (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591301
[Presentation] NQO1 Expression Predicts OS and Response to Preoperative Chemotherapy in Colorectal Liver Metastasis2019
- Author(s)
  廣瀬雄己、坂田純、小林隆、滝沢一泰、三浦宏平、堅田朋大、永橋昌幸、島田能史、市川寛、亀山仁史、若井俊文
- Organizer
  14th ANNUAL ACADEMIC SURGICAL CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10663
[Presentation] Macrophage migration inhibitory factor expression predicts clinical outcomes in patients with resected pancreatic ductal adenocarcinoma2019
- Author(s)
  Kabuto Takano, Jun Sakata, Yuki Hirose, Kohei Miura, Hiroshi Ichikawa, Masayuki Nagahashi, Yoshifumi Shimada, Hitoshi Kameyama, Takashi Kobayashi, Toshifumi Wakai
- Organizer
  The 7th Biennial Congress of the Asian-Pacific-Hepato-Pancreato-Biliary Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10690
[Presentation] Defective Homologous Recombination in Platinum-based Chemotherapy for Gastric Cancer2019
- Author(s)
  T. Katada, H. Ichikawa, Y. Hirose, M. Nagahashi, Y. Shimada, T. Hanyu, T. Ishikawa, Y. Kano, Y. Muneoka, J. Sakata, T. Kobayashi, H. Kameyama, T. Wakai
- Organizer
  14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08698
[Presentation] Sphingosine-1-phospate Signaling Regulates Drug Resistance Mediated by Glutathione2019
- Author(s)
  Nagahashi M, Tsuchida J, Moro K, Ikarashi M, Nakajima M, Abe M, Saito T, Komatsu M, Soga T, Takabe K, Sakimura K, Wakai T
- Organizer
  The 14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] Pathogenic germline BRCA1/2 mutations and familial predisposition to gastric cancer2018
- Author(s)
  Ichikawa H，Nagahashi M，Shimada Y，Hanyu T，Ishikawa T，Muneoka Y，Kano Y，Takizawa K，Miura K，Hirose Y，Yuza K，Tsuchida J，Sakata J，Kobayashi T，Kameyama H，Yabusaki H，Nakagawa S，Okuda S，Takabe K，Wakai T
- Organizer
  2018 American Society of Clinical Oncology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10580
[Presentation] 大腸癌肝転移に対する術前化学療法　NQO1発現を用いた治療効果予測の可能性2018
- Author(s)
  相馬大輝、坂田純、小林隆、滝沢一泰、三浦宏平、堅田朋大、石川博補、廣瀬雄己、峠弘治、油座築、安藤拓也、田島陽介、市川寛、羽入隆晃、永橋昌幸、中島真人、島田能史、亀山仁史、若井俊文
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10663
[Presentation] High levels of sphingolipids in human pancreatic cancer2018
- Author(s)
  K. Yuza, M. Nagahashi, Y. Hirose, M. Nakajima, K. Miura, H. Ichikawa, Y. Shimada, J. Sakata, H. Kameyama, T. Kobayashi, K. Takabe, T. Wakai
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Sphingosine-1-phosphate produced by sphingosine kinase type 1 and type 2 works differently in pancreatic cancer2018
- Author(s)
  M. Nakajima, K. Yuza, J. Tsuchida, Y. Hirose, K. Miura, H. Ichikawa, Y. Shimada, T. Kobayashi, J. Sakata, H. Kameyama, M. Abe, K. Sakimura, T. Wakai, M. Nagahashi
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] High Expression of Sphingosine Kinase 1 in Colitis-Associated Cancer2018
- Author(s)
  Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Ichikawa H, Sakata J, Kobayashi T, Takabe K, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] 胆管生検で採取した正常上皮・炎症上皮・癌組織におけるDNA二本鎖切断のマーカーであるγH2AX発現の検討2018
- Author(s)
  廣瀬雄己, 坂田純, 安藤拓也, 油座築, 堅田朋大, 三浦宏平, 滝沢一泰, 永橋昌幸, 小林隆, 若井俊文
- Organizer
  日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10691
[Presentation] ヒト胆道癌組織における脂質メディエーターS1Pの発現とその意義2018
- Author(s)
  廣瀬雄己, 永橋昌幸, 油座築, 安藤拓也, 相馬大輝, 諸和樹, 峠弘治, 石川博補, 堅田朋大, 三浦宏平, 市川寛, 滝沢一泰, 中島真人, 島田能史, 坂田純, 小林隆, 亀山仁史, 若井俊文
- Organizer
  第118回日本外科学会定期学術集会（東京都）
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] Chemotherapeutic biomarkers for predicting tumor response in patients with gastric cancer: Defective homologous2018
- Author(s)
  Ichikawa H，Hanyu T，Ishikawa T，Katada T，Shimada Y，Sakata J，Kobayashi T，Nakagawa S，Kameyama H，Wakai T
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10580
[Presentation] シンポジウム 5　ゲノム医療推進に向けた取り組みの課題と展望　当科におけるゲノム医療推進に向けた取組み2018
- Author(s)
  永橋　昌幸，土田　純子，遠藤　麻巳子，諸　和樹，庭野　稔之，山浦　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，神林　智寿子，金子　耕司，佐藤　信昭，若井　俊文
- Organizer
  第26回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] The Significance of Phospho-Sphingosine Kinase 1 in the Lymphatic Spread of Esophageal Carcinoma2018
- Author(s)
  Ichikawa H, Nagahashi M, Nemoto M, Hanyu T, Ishikawa T, Kano Y, Muneoka Hirose Y, Shimada Y, Sakata J, Kobayashi T, Kameyama H, Kazuaki T, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] High Levels of Sphingolipids in Human Pancreatic Cancer2018
- Author(s)
  Yuza K, Nagahashi M, Hirose Y, Nakajima M, Miura K, Ichikawa H, Shimada Y, Sakata J, Kameyama H, Kobayashi T, Takabe K, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] 食道扁平上皮癌リンパ行性進展におけるphospho-sphingosine kinase 1発現の意義2018
- Author(s)
  市川　寛，根本　万理子，石川　卓，羽入　隆晃，角田　知行，須藤　翔，島田　能史，永橋　昌幸，坂田　純，小林　隆，亀山　仁史，若井　俊文
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] 潰瘍性大腸炎関連大腸癌診断における脂質メディエーター(S1P)解析の有用性2018
- Author(s)
  亀山仁史，永橋昌幸，油座　築，田島陽介，羽入隆晃，中野雅人，中島真人，島田能史，坂田　純，若井俊文
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] 大腸癌肝転移におけるNQO1発現が肝切除術後の遠隔成績に与える影響2018
- Author(s)
  廣瀬雄己、坂田純、安藤拓也、油座築、峠弘治、堅田朋大、三浦宏平、滝沢一泰、小林隆、永橋昌幸、島田能史、亀山仁史、若井俊文
- Organizer
  第26回日本消化器関連週間（第17回日本消化器外科学会大会）
- Data Source
  KAKENHI-PROJECT-17K10663
[Presentation] Dysregulation of Sphingolipids in Human Hepatocellular Carcinoma2018
- Author(s)
  Miura K, Nagahashi M, Hirose Y, Kobayashi T, Sakata J, Kameyama H, Shimada Y, Ichikawa H, Takabe K, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] Sphingosine Kinase Type 1 and Type 2 Works Differently in Pancreatic Cancer2018
- Author(s)
  Nakajima M, Yuza K, Tsuchida J, Hirose Y, Miura K, Ichikawa H, Shimada Y, Kobayashi T, Sakata J, Kameyama H, Abe M, Sakimura K, Wakai T, Nagahashi M
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] Dysregulation of Sphingolipids in Human Hepatocellular Carcinoma2018
- Author(s)
  K. Miura, M. Nagahashi, Y. Hirose, T. Kobayashi, J. Sakata, H. Kameyama, Y. Shimada, H. Ichikawa, K. Takabe, T. Wakai
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] High Expression of Sphingosine Kinase 1 in Colitis-Associated Cancer2018
- Author(s)
  Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Ichikawa H, Sakata J, Kobayashi T, Takabe K, Wakai T
- Organizer
  14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] Human Biliary Tract Cancer Contains High Levels of S1P2018
- Author(s)
  Hirose Y, Nagahashi M, Yuza K, Miura K, Sakata J, Kobayashi T, Ichikawa H, Shimada Y, Kameyama H, Takabe K, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] 潰瘍性大腸炎に合併した大腸癌（colitic cancer）におけるリン酸化スフィンゴシンキナーゼ1高発現の意義2018
- Author(s)
  油座　築、永橋昌幸、島田能史、中野麻恵、田島陽介、亀山仁史、中島真人、市川　寛、坂田　純、小林　隆、高部和明、若井俊文
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] 胆管生検組織標本の良・悪性判定にγH2AX発現が有用である2018
- Author(s)
  石川博補, 廣瀬雄己, 永橋昌幸, 坂田純, 相馬大輝, 安藤拓也, 油座築, 堅田朋大, 三浦宏平, 滝沢一泰, 小林隆, 田島陽介, 市川寛, 羽入隆晃, 島田能史, 亀山仁史, 若井俊文
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10691
[Presentation] 肥満が引き起こす慢性炎症による乳癌の転移促進と脂質メディエーターの役割2018
- Author(s)
  永橋　昌幸，土田　純子，油座　築，中島　真人，高部　和明，若井　俊文
- Organizer
  第25回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] 肝細胞癌患者における脂質メディエーター・スフィンゴシン-1-リン酸及びセラミドの定量とその意義2018
- Author(s)
  永橋昌幸, 廣瀬雄己, 三浦宏平, 油座築, 相馬大輝, 安藤拓也, 峠弘治, 石川博輔, 堅田朋大, 坂田純, 小林隆, 中島真人, 羽入隆晃, 市川寛, 石川卓, 島田能史, 亀山仁史, 高部和明, 若井俊文
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08672
[Presentation] がんプレシジョンメディシン実現に向けたバイオインフォマティクス：遺伝子変異と治療薬の知識ベース2018
- Author(s)
  竹内志穂、凌一葦、渡邉由、若井俊文、奥田修二郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04123
[Presentation] The Significance of Phospho-Sphingosine Kinase 1 in the Lymphatic Spread of Esophageal Carcinoma2018
- Author(s)
  Hiroshi Ichikawa, Masayuki Nagahashi, Mariko Nemoto, Takaaki Hanyu, Takashi Ishikawa, Yosuke Kano, Yusuke Muneoka, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] Human biliary tract cancer contains high levels of S1P2018
- Author(s)
  Yuki Hirose, Masayuki Nagahashi, Kizuki Yuza, Kohei Miura, Jun Sakata, Takashi Kobayashi, Hiroshi Ichikawa, Yoshifumi Shimada, Hitoshi Kameyama, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 13th Annual Academic Surgical Congress (Florida, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] Human biliary tract cancer contains high levels of S1P2018
- Author(s)
  Y. Hirose, M. Nagahashi, K. Yuza, K. Miura, J. Sakata, T. Kobayashi, H. Ichikawa, Y. Shimada, H. Kameyama, K. Takabe, T. Wakai
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] リン酸化スフィンゴシンキナーゼ1の発言と胃癌の進行についての関連2018
- Author(s)
  羽入隆晃, 永橋昌幸, 市川寛, 石川卓, 角田知行, 須藤翔, 根本万理子, 小杉伸一, 島田能史, 坂田純, 小林隆, 亀山仁史, 若井俊文
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15K10087
[Presentation] Tumor mutation burden in triple negative breast cancer patients in Japan2018
- Author(s)
  Nagahashi M, Ling Y, Hayashida T, Kitagawa Y, Futamura M, Yoshida K, Kuwayama T, Nakamura S, Toshikawa C, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Miyoshi Y, Tsuchida J, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Takabe K, Okuda S, Wakai T
- Organizer
  2018 American Society of Clinical Oncology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] 胃癌における相同組換え修復機構の破綻と予後2018
- Author(s)
  市川　寛，羽入　隆晃，石川　卓，加納　陽介，宗岡　悠介，堅田　朋大，島田　能史，永橋　昌幸，坂田　純，小林　隆，亀山　仁史，中川　悟，若井　俊文
- Organizer
  第26回日本消化器関連学会週間JDDW2018
- Data Source
  KAKENHI-PROJECT-17K10580
[Presentation] 胃癌におけるDNAミスマッチ修復遺伝子変異とアクチビン2型受容体遺伝子変異の検討2017
- Author(s)
  油座　築，永橋　昌幸，市川　寛，島田　能史，若井　俊文
- Organizer
  第5回新潟大学医学系基礎-臨床研究交流会
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] Association of activin type II receptor mutation with microsatellite instability in gastric cancer.2017
- Author(s)
  Yuza K，Nagahashi M，Ichikawa H，Nakajima M，Hanyu T，Ishikawa T，Shimada Y，Sakata J，Kameyama H，Kobayashi T，Nakagawa S，Sato N，Honma K，Kawasaki T，Okuda S，Takabe K，Wakai T
- Organizer
  2017 ASCO Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] Expression of phosphorylated sphingosine kinase 1 is associated with invasiveness of gastric cancer2017
- Author(s)
  Takaaki Hanyu, Masayuki Nagahashi, Hiroshi Ichikawa, Takashi Ishikawa, Shin-ichi Kosugi, Masato Nakajima, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas（USA）
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10087
[Presentation] 膵がんにおけるCRISPR/Cas9を用いたスフィンゴシン-1-リン酸産生酵素の機能解析2017
- Author(s)
  中島　真人，永橋　昌幸，三浦　要平，安藤　拓也，油座　築，土田　純子，田島　陽介，坂田　純，小林　隆，亀山　仁史，阿部　学，崎村　建司，若井　俊文
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Expression of phosphorylated sphingosine kinase 1 is associated with invasiveness of gastric cancer2017
- Author(s)
  Takaaki Hanyu, Masayuki Nagahashi, Hiroshi Ichikawa, Takashi Ishikawa, Shin-ichi Kosugi, Masato Nakajima, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  The 12th Annual Academic Surgical Congress（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10087
[Presentation] Function Analysis of Sphingosine-1-Phosphate Produced by Sphingosine Kinases in Pancreatic Cancer Progression.2017
- Author(s)
  Masato Nakajima，Masayuki Nagahashi，Junko Tsuchida，Hiroshi Ichikawa，Yoshifumi Shimada，Toshifumi Wakai
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] 膵癌細胞におけるスフィンゴシン-1-リン酸産生酵素の働きとその代謝動態制御の解析2017
- Author(s)
  中島　真人，永橋　昌幸，三浦　要平，安藤　拓也，油座　築，土田　純子，田島　陽介，坂田　純，小林　隆，亀山　仁史，阿部　学，﨑村　建司，曽我　朋義，若井　俊文
- Organizer
  日本外科代謝栄養学会第54回学術集会
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] 胃癌におけるマイクロサテライト不安定性とアクチビン受容体遺伝子変異の検討2017
- Author(s)
  油座　築，永橋　昌幸，市川　寛，羽入　隆晃，石川　卓，中島　真人，島田　能史，坂田　純，亀山　仁史，小林　隆，中川　悟，井筒　浩，兒玉　啓輔，高部　和明，若井　俊文
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] Roles of Sphingosine-1-Phosphate Produced by Sphingosine Kinases in Pancreatic Cancer Progression2017
- Author(s)
  Nakajima M, Miura Y, Ando T, Yuza K, Tsuchida J, Tajima Y, Abe M, Sakimura K, Wakai T, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] Expression of phosphorylated sphingosine kinase 1 is associated with invasiveness of human gastric cancer2017
- Author(s)
  Takaaki Hanyu, Masayuki Nagahashi, Hiroshi Ichikawa, Takashi Ishikawa, Shin-ichi Kosugi, Masato Nakajima, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  第89回日本胃癌学会総会
- Data Source
  KAKENHI-PROJECT-15K10087
[Presentation] Validity of adding intravenous carnitine to parenteral nutrition with lipid emulsion for deceasing inflammatory reaction of postoperative surgical patients.2017
- Author(s)
  Koyama Y, Moro K, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Shimada Y, Kameyama H, Kobayashi T, Wakai T
- Organizer
  39th ESPEN
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] Activin type II receptor as an affordable surrogate to identify microsatellite instability2017
- Author(s)
  Yuza K，Nagahashi M，Ichikawa H，Hanyu T，Ishikawa T，Shimada Y，Sakata J，Kameyama H，Kobayashi T，Izutsu H，Kodama K，Takabe K，Wakai T
- Organizer
  12th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] 膵癌切除例における Macrophage migration inhibitory factorの発現と治療成績2017
- Author(s)
  高野可赴、滝沢一泰、坂田純、小林隆、若井俊文、安藤拓也、油座築、峠弘治、石川博補、三浦宏平、大橋拓、市川寛、羽入隆晃、永橋昌幸、石川卓、亀山仁史
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10690
[Presentation] Symposia S1：New trends for studying cancer invasion and metastasis The role of sphingosine-1-phosphate in tumor microenvironment and metastasis2017
- Author(s)
  Nagahashi M, Tsuchida J, Nakajima M, Takabe K, Wakai T
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] Association between Activin receptor type 2A mutation and microsatellite instability in gastric cancer2017
- Author(s)
  Yuza K，Nagahashi M，Ichikawa H，Shimada Y，Nakajima M，Takabe K，Wakai T
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] Sphingosine-1-phosphate in the Lymphatic Fluid Determined by Novel Methods2017
- Author(s)
  Nagahashi M, Yamada A, Aoyagi T, Allegood J, Wakai T, Spiegel S, Takabe K
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] γH2AX expression discriminates between benign and malignant biliary tract biopsy specimens2017
- Author(s)
  Yuki HIROSE, Masayuki NAGAHASHI, Hirosuke ISHIKAWA, Kizuki YUZA, Kohei MIURA, Hiroshi ICHIKAWA, Yoshifumi SHIMADA, Hitoshi KAMEYAMA, Jun SAKATA, Takashi KOBAYASHI, Toshifumi WAKAI
- Organizer
  Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10691
[Presentation] 周術期末梢静脈栄養　脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果.2017
- Author(s)
  諸　和樹, 小山　諭, 永橋　昌幸, 三浦　宏平, 土田　純子, 中島　真人, 若井　俊文.
- Organizer
  第54回日本外科代謝栄養学会
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] 周術期末梢静脈栄養：脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果2017
- Author(s)
  諸　和樹、小山　諭、永橋昌幸、三浦宏平、土田純子、中島真人、若井俊文１
- Organizer
  第5４回日本外科代謝栄養学会
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター（新潟県新潟市）
- Year and Date
  2017-07-06
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] MED 12 expression may be a significant prognosis prediction in colorectal cancer.2016
- Author(s)
  Toge K, Shimada Y, Tajima Y, Kameyama H, Yagi R, Okamura T, Hirose Y, Sakata J, Kobayashi T, Ajioka Y, Wakai T
- Organizer
  26th World Congress of International Association of Surgeons, Gastroenterologists and Oncologists
- Place of Presentation
  Seoul, Korea
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10130
[Presentation] Clinical significance of NQO1 expression in nontumorous squamous epithelium of esophageal cancer patients2016
- Author(s)
  Kosugi S, Ichikawa H, Hanyu T, Ishikawa T, Wakai T
- Organizer
  15th World Congress of the International Society for Diseases of the Esophagus
- Place of Presentation
  Singapore (Republic of Singapore)
- Year and Date
  2016-09-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461971
[Presentation] 5-Aminolevulinic Acid-induced Fluorescence Relates to Prognosis in Pancreatic Cancer2016
- Author(s)
  Masahiro Minagawa, Tetsuya Naito, Jun Hasegawa, Tatsuo Tani, Naohiro Shimakage,　Kazuyasu Takizawa, Kabuto Takano, Toshifumi Wakai
- Organizer
  71th General Meeting of the Japanese Society of Gastroenterological Surgery
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2016-07-15
- Data Source
  KAKENHI-PROJECT-26462055
[Presentation] 周術期末梢静脈栄養における脂肪乳剤とカルニチン投与の検討2016
- Author(s)
  小山　諭、諸　和樹、永橋昌幸、三浦宏平、辰田久美子、土田純子、中島真人、若井俊文
- Organizer
  第53回日本外科代謝栄養学会
- Place of Presentation
  伊藤国際学術研究センター(東京都文京区）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] 肥満を伴う乳癌患者における血清スフィンゴシン-1-リン酸の定量2016
- Author(s)
  土田純子, 永橋昌幸, 遠藤麻巳子, 大溪彩香, 庭野稔之, 辰田久美子, 利川千絵, 長谷川美樹, 五十嵐麻由子, 中島真人, 小山諭, 高部和明, 若井俊文
- Organizer
  第78回　日本臨床外科学会総会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] 大腸癌化学療法におけるNQO1発現解析の意義2016
- Author(s)
  亀山仁史，廣瀬雄己，島田能史，八木亮磨，田島陽介，岡村拓磨，中野雅人，市川　寛，永橋昌幸，坂田　純，小林　隆，若井俊文
- Organizer
  JDDW 2016
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-26462006
[Presentation] スフィンゴシンキナーゼ欠損細胞の開発とその機能解析2016
- Author(s)
  中島真人, 永橋昌幸, 土田純子, 市川寛, 島田能史, 若井俊文
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Clinical significance of NQO1 expression in patients with KRAS wild-type unresectable colorectal cancer2016
- Author(s)
  Hitoshi Kameyama, Yuki Hirose, Yoshifumi Shimada, Ryoma Yagi, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Masayuki Nagahashi, Takashi Kobayashi, Toshifumi Wakai
- Organizer
  IASGO 2016
- Place of Presentation
  Seoul (South Korea)
- Year and Date
  2016-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462006
[Presentation] 膵癌におけるアミノレブリン酸蛍光と予後との相関2016
- Author(s)
  皆川昌広　内藤哲也　長谷川潤　谷達夫　島影尚弘滝沢一泰　高野可赴　若井俊文
- Organizer
  第７１回日本消化器外科学会総会
- Place of Presentation
  アスティ徳島（徳島県、徳島市）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26462055
[Presentation] スフィンゴシンキナーゼ欠損細胞の開発とその機能解析2016
- Author(s)
  中島真人, 永橋昌幸, 土田純子, 市川寛, 島田能史, 若井俊文
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] 検診発見および自己発見乳癌の臨床病理学的特徴と長期成績2016
- Author(s)
  土田純子, 永橋昌幸, 諸和樹, 庭野稔之, 辰田久美子, 利川千絵, 長谷川美樹, 萬羽尚子, 五十嵐麻由子, 小山諭, 市川寛, 中島真人, 島田能史, 坂田純, 小林隆, 亀山仁史, 若井俊文
- Organizer
  第116回　日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] 大腸癌における転写メディエーターMED12異常発現の臨床的意義．2016
- Author(s)
  島田能史，田島陽介，亀山仁史，八木亮磨，岡村拓磨，中野雅人，坂田　純，小林　隆，小杉伸一，若井俊文．
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  アスティとくしま（徳島県、徳島市）
- Data Source
  KAKENHI-PROJECT-15K10130
[Presentation] 胆汁酸はスフィンゴシン-1-リン酸シグナル伝達系を介して肝臓における脂質代謝を調節している2015
- Author(s)
  永橋　昌幸，廣瀬　雄己，須藤　翔，大橋　拓，滝沢　一泰，高野　可赴，坂田　純，小林　隆，若井　俊文
- Organizer
  第51日本胆道学会学術集会
- Place of Presentation
  ホテル東日本宇都宮（栃木県宇都宮市）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] 肝胆膵「肝胆膵外科診療の最前線」2015
- Author(s)
  若井俊文
- Organizer
  第53回日本癌治療学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] 肥満はスフィンゴシン-1-リン酸を癌微小環境において増加させる2015
- Author(s)
  永橋　昌幸，諸　和樹，土田　純子，辰田　久美子，利川　千絵，長谷川　美樹，萬羽　尚子，五十嵐　真由子，坂田　純，小林　隆，亀山　仁史，皆川　昌広，小杉　伸一，小山　諭，高部　和明，若井　俊文
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] IMPACT OF SURGICAL RESECTION AND CHEMOTHERAPY ON LONG-TERM OUTCOMES IN PATIENTS WITH LOCALLY ADVANCED GALLBLADDER CARCINOMA2015
- Author(s)
  T. Wakai, J. Sakata, Y. Hirose, N. Sudo, T. Katada, K. Takizawa, M. Nagahashi, T. Kobayashi
- Organizer
  46th World Congress of Surgery
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2015-08-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] SymposiumⅢ Laparoscopic cholecystectomy with LN dissection2015
- Author(s)
  Toshifumi Wakai
- Organizer
  The 36th Annual Meeting of the Korean Society of Endoscopic & Laparoscopic Surgeons, 2015 International Symposium
- Place of Presentation
  Jeju, Korea
- Year and Date
  2015-05-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Expression of NQO1 in esophageal cancer cells after neoadjuvant chemotherapy2014
- Author(s)
  Takashi Ishikawa, Shin-ichi Kosugi, Hiroshi Ichikawa, Takaaki Hanyu, Tsutomu Suzuki, Toshifumi Wakai
- Organizer
  14th World Congress of The International Society for Diseases of the Esophagus
- Place of Presentation
  The Westin Bayshore（バンクーバー、カナダ）
- Year and Date
  2014-09-24
- Data Source
  KAKENHI-PROJECT-26461971
[Presentation] 大腸粘膜下層浸潤癌における簇出（budding）の組織学的評価2014
- Author(s)
  岡村拓磨、島田能史、若井俊文、味岡洋一
- Organizer
  日本大腸肛門病学会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-26462007
[Presentation] Regional lymphadenectomy for gallbladder cancer : rational extent and patient outcomes2014
- Author(s)
  Sakata J, Wakai T, Hirose Y, Katada T, Sudo N, Ohashi T, Takizawa K, Takano K, Kobayashi T, Minagawa M.
- Organizer
  IHPBA World Congress 2014
- Place of Presentation
  Seoul, Korea
- Year and Date
  2014-03-25
- Data Source
  KAKENHI-PROJECT-23592004
[Presentation] VALPROIC ACID CONFERS RESISTANCE TO SORAFENIB IN MICE WITH HEPATOCELLULAR CARCINOMA2013
- Author(s)
  Y. Matsuda, M. Osawa, S. Fujimaki, T. Wakai, M. Kubota, M. Takamura, S. Yamagiwa, Y. Aoyagi
- Organizer
  欧州消化器病学会
- Place of Presentation
  ベルリン(ドイツ）
- Data Source
  KAKENHI-PROJECT-24590962
[Presentation] 潰瘍性大腸炎の炎症性発癌過程におけるDNA損傷2013
- Author(s)
  谷　優佑、味岡洋一、渡辺佳緒里、若井俊文、山口尚之、高林広明、小林和恵
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590391
[Presentation] Assessment of lymph node status in gallbladder cancer: location, number, or ratio of positive nodes2013
- Author(s)
  Sakata J, Ohashi T, Hirose Y, Takizawa K, Takano K, Kobayashi T, Minagawa M, Wakai T
- Organizer
  International Surgical Week 2013
- Place of Presentation
  Helsinki, Finland
- Data Source
  KAKENHI-PROJECT-23592004
[Presentation] 潰瘍性大腸炎の炎症性発癌過程におけるDNA損傷応答2013
- Author(s)
  谷優佑, 味岡洋一, 渡辺佳緒里, 若井俊文, 山口尚之, 高林広明, 小林和恵
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Year and Date
  2013-06-07
- Data Source
  KAKENHI-PROJECT-23590391
[Presentation] Assessment of lymph node status in gallbladder cancer : location, number, or ratio of positive nodes2013
- Author(s)
  Sakata J, Ohashi T, Hirose Y, Takizawa K, Takano K, Kobayashi T, Minagawa M, Wakai T.
- Organizer
  International Surgical Week 2013
- Place of Presentation
  Helsinki, Finland
- Data Source
  KAKENHI-PROJECT-23592004
[Presentation] 大腸腫瘍の発育進展における, 53BP1を介したDNA損傷修復応答の変化2011
- Author(s)
  高林広明, 味岡洋一, 若井俊文.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23590391
[Presentation] Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2011
- Author(s)
  Wakai T, Shirai Y, Sakata J, Korita PV, Nagahashi M, Ajioka Y, Hatakeyama K
- Organizer
  INTERNATIONAL SURGICAL WEEK 2011
- Place of Presentation
  Yokohama
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-21591768
[Presentation] Early DNA Damage Response and Local Recurrence at Ductal Resection Margins in Patients Undergoing Resection for Extrahepatic Cholangiocarcinoma2010
- Author(s)
  Wakai T, Shirai Y, Sakata J, Korita PV, Nagahashi M, Hatakeyama K
- Organizer
  96th Annual Clinical Congress, American College of Surgeons
- Place of Presentation
  Washington, DC
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PROJECT-21591768
[Presentation] 肝門部胆管癌術後の胆管切離断端部遺残腫瘍におけるDNA damage responseと予後との関連2010
- Author(s)
  若井俊文, 他
- Organizer
  第65回日本消化器外科学会総会
- Place of Presentation
  下関
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21591768
[Presentation] <ワークショップ>肝門部胆管癌術後の胆管切離断端部遺残腫瘍におけるDNA damage responseと予後との関連2010
- Author(s)
  若井俊文,白井良夫,坂田純,永橋昌幸,井上真,畠山勝義
- Organizer
  第65回日本消化器外科学会総会
- Place of Presentation
  下関
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21591768
[Presentation] 胆管癌における53BP1を介したDNA損傷修復機構の解明及びその臨床的意義2009
- Author(s)
  若井俊文
- Organizer
  第17回日本消化器関連学会週間 JDDW 2009
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-21591768
[Presentation] 胆管断端における癌遺残が肝外胆管癌根治術後の遠隔成績に与える影響2009
- Author(s)
  若井俊文,白井良夫,坂田純,金子和弘,永橋昌幸,畠山勝義
- Organizer
  第64回日本消化器外科学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-07-16
- Data Source
  KAKENHI-PROJECT-21591768
[Presentation] 胆管癌における53BP1を介したDNA損傷修復機構の解明及びその臨床的意義2009
- Author(s)
  若井俊文,白井良夫,松田康伸,坂田純,味岡洋一,畠山勝義
- Organizer
  第17回日本消化器関連学会週間JDDW 2009
- Place of Presentation
  京都
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-21591768
[Presentation] 胆管癌根治切除後の胆管切離断端部遺残腫瘍におけるDNA damage responseと局所再発との関連2009
- Author(s)
  若井俊文
- Organizer
  第45回日本胆道学会学術集会
- Place of Presentation
  東京ベイ幕張(千葉)
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21591768
[Presentation] 胆管癌根治切除後の胆管切離断端部遺残腫瘍におけるDNA damage responseと局所再発との関連2009
- Author(s)
  若井俊文,白井良夫,坂田純,金子和弘,永橋昌幸,畠山勝義
- Organizer
  第45回日本胆道学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21591768
[Presentation] 脈管侵襲を伴う肝細胞癌における細胞接着因子の臨床的意義2007
- Author(s)
  Pavel Korita, 若井俊文, 白井良夫, 他
- Organizer
  第107回日本外科学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-04-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591504
[Presentation] Clinical significance of cell adhesion molecules in hepatocellular carcinoma with vascular invasion2007
- Author(s)
  Korita, P, Wakai, T, Shirai, Y, et. al.
- Organizer
  The 107th Annual Congress of Japan Surgical Society
- Place of Presentation
  Osaka
- Year and Date
  2007-04-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591504
[Presentation] 表層拡大進展を伴う広範囲胆管癌に対する術前評価と外科治療戦略
- Author(s)
  若井俊文，堅田朋大，須藤　翔，齋藤敬太，丸山智宏，滝沢一泰，坂田　純，高野可赴，小林　隆，皆川昌広
- Organizer
  第69回日本消化器外科学会総会
- Place of Presentation
  郡山、ホテルハマツ2Ｆ白鳥第14会場
- Year and Date
  2014-07-18 – 2014-07-20
- Data Source
  KAKENHI-PROJECT-24592021
[Presentation] TGF-BETA IS A CRITICAL MEDIATOR OF SORAFENIB RESISTANCE IN HEPATOCELLULAR CARCINOMA
- Author(s)
  Y. Matsuda, M. Osawa, T. Wakai, M. Kubota
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590962
[Presentation] NQO1 EXPRESSION HAS PROGNOSTIC SIGNIFICANCE IN KRAS-WILD UNRESECTABLE COLORECTAL CANCER
- Author(s)
  Y. Hirose, H. Kameyama, T. Ohashi, K. Takizawa, M. Nagahashi, T. Kobayashi, J. Sakata, T. Wakai
- Organizer
  46th World Congress of Surgery
- Place of Presentation
  Bangkok
- Year and Date
  2015-08-23 – 2015-08-27
- Data Source
  KAKENHI-PROJECT-26462006
[Presentation] 5-Aminolevulinic Acid-induced Fluorescence Relates to the Gemcitabine Clearance in Pancreatic Cancer
- Author(s)
  Masahiro Minagawa, Kazuyasu Takizawa, Kohei Miura, Jun Sakata, Takashi Kobayashi, Toshifumi Wakai
- Organizer
  Asian-Pacific Hepato-Pancreato-Biliary Association
- Place of Presentation
  シンガポール
- Year and Date
  2015-03-18 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26462055
[Presentation] 進行再発大腸癌におけるNQO1発現の臨床的意義
- Author(s)
  亀山仁史，廣瀬雄己，佐藤　洋，山田沙季，阿部　馨，庭野稔之，岩城孝和，八木亮磨，田島陽介，中野麻恵，中野雅人，島田能史，坂田　純，小林　隆，皆川昌広，小杉伸一，小山　諭，若井俊文
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Year and Date
  2014-04-16 – 2014-04-18
- Data Source
  KAKENHI-PROJECT-26462006
[Presentation] 胆道癌として外科切除された良性胆管病変の検討
- Author(s)
  若井俊文、坂田　純、皆川昌広
- Organizer
  第49回日本胆道学会学術集会
- Place of Presentation
  浦安
- Data Source
  KAKENHI-PROJECT-24592021
[Presentation] Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma
- Author(s)
  Toshifumi Wakai
- Organizer
  11th World Congress oh the International Hepato-Pancreato-Biliary Association
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-24592021

1. NAGAHASHI Masayuki (30743918)

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52. 榎本隆之 (90283754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. 吉原弘祐 (40547535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. 臼井賢司 (70769413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. Hylemon Phillip B.

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
56. MUNEOKA Yusuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
57. TANAKA Kana

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. SAKIMURA Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
59. 横山直行

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
60. 廣田誠一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 石井大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Wakai Toshifumi 若井 俊文

WAKAI Toshifumi 若井 俊文

Research Projects

Research Products

Co-Researchers

乳癌免疫微小環境における脂質メディエーター分子の役割解明と治療応用を目指した研究Ongoing

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卵巣癌肝転移における直腸間膜リンパ節転移を経由した新たな転移経路の解明Ongoing

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HER2陽性胃癌における遺伝子異常の包括的評価と臨床的意義の解明Ongoing

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Elucidation of the interaction between human commensal bacterial flora and host genetic alterations in the digestive tractPrincipal InvestigatorOngoing

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がんゲノム医療実現化に向けた高次元データ解析基盤構築Ongoing

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発癌の分子メカニズムの違いに着目した大腸癌TGF-βシグナル伝達経路の新たな分類Ongoing

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肝細胞癌の脈管侵襲における脂質メディエーター分子機構の解明と臨床的意義Ongoing

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Clinical significance of defective DNA double-strand break repair pathway in gastric cancerOngoing

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Mechanisms of cancer metabolism and drug resistance regulated by S1P in triple negative breast cancerOngoing

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大腸de novo癌の発生分子メカニズムの解明Ongoing

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胃癌におけるアクチビン受容体変異による新規シグナル伝達機構の解明及び臨床的意義Ongoing

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胃癌におけるBRCA1/2遺伝子変異解析およびタンパク質発現とその臨床的意義Ongoing

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潰瘍性大腸炎関連大腸癌における脂質メディエーターを介した新たな発癌機構の解明Ongoing

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Wakai Toshifumi 若井俊文

WAKAI Toshifumi 若井俊文