Koyama Yuu 小山諭

… Alternative Names

Researcher Number	10323966
Other IDs
Affiliation (Current)	2019: 新潟大学, 医歯学系, 教授
Affiliation (based on the past Project Information) *help	2014 – 2019: 新潟大学, 医歯学系, 教授 2014: 新潟大学, 医歯学系, 准教授 2007 – 2008: 新潟大学, 医歯学系, 助教 2005 – 2006: 新潟大学, 医歯学系, 助手 2002 – 2004: 新潟大学, 大学院・医歯学総合研究科, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / General surgery Except Principal Investigator Digestive surgery / General surgery / Society medicine, Nursing, and related fields / Medical sociology / Basic Section 58060:Clinical nursing-related / Community health nursing
Keywords	Principal Investigator CRP / ビタミンD3 / 乳び胸 / 胃切除後患者 / 骨粗鬆症 / 骨型アルカリフォスファーゼ(BAP) / カルニチン / RTP / Rapid turnover protein / 骨型アルカリフォスファターゼ(BAP) … More Except Principal Investigator スフィンゴシン-1-リン酸 / 食道癌 / ケアプログラム / 摂食嚥下障害 / p62 / DNA二重鎖切断 / 訪問看護ステーション / 抗エストロゲン剤耐性株 / field carcinogenesis / PCR / 乳癌 / 食道外科学 / NQO1 / 在宅褥瘡 / 空腹感 / 血中微小癌細胞 / 治療抵抗性 / 表層拡大進展 / 再発 / 食支援 / QOL / CEA / 看護教育 / 血中癌細胞 / 食欲不振 / 地域看護学 / SCC / 誤嚥性肺炎予防 / 酸化ストレス / 薬剤耐性 / 頭皮悪化 / プログラム / 上皮内癌 / KRAS / Nrf2 / 術前補助化学療法 / 感覚モダリティ / 摂食嚥下障害ケア / 連携型 / 小児がん患児のQOL / 小児がん患児 / p53-binding protein 1 / メタボローム / 臨床試験 / スフィンゴシンキナーゼ / 褥瘡 / 癌代謝 / 栄養 / DNA損傷修復機構 / Keap1 / 抗がん剤脱毛 / 子どもの食行動尺度 / スフィンゴシンキナーゼ１型 / 胆管癌 / 消化管間質腫瘍 / 脂質メディエーター / 皮膚・排泄ケア認定看護師 / γ-H2AX / スフィンゴシン-１-リン酸 / 食意欲の心理量測定 / 褥瘡管理 / 小児がん / 大腸癌 / 早期DNA損傷修復機構 / コンピテンシー / 認定看護師 / 装着型ウェアラブル端末 / 術前化学療法 / CRISPR/Cas9 / 感覚モダリティ変換 / 在宅患者訪問看護 / 抗癌剤耐性 / 精神科 Less

抗がん剤脱毛時の頭皮悪化が予測できるウィッグ装着型ウェアラブル端末の開発Ongoing
- Principal Investigator
  
  内山美枝子
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Niigata University
感覚モダリティ変換を応用した小児がん患児の食意欲の心理量測定ツールの開発Ongoing
- Principal Investigator
  
  住吉智子
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical sociology
- Research Institution
  Niigata University
乳癌ホルモン療法耐性機序における脂質メディエーター分子機構の解明および臨床的意義Ongoing
- Principal Investigator
  
  五十嵐麻由子
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Niigata University
精神科における誤嚥性肺炎予防のための連携型摂食嚥下障害ケアプログラムの開発Ongoing
- Principal Investigator
  
  清野由美子
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Challenging Research (Exploratory)
- Research Field
  
  Society medicine, Nursing, and related fields
- Research Institution
  Niigata University
皮膚・排泄ケア認定看護師の在宅褥瘡管理コンピテンシーリストの開発Ongoing
- Principal Investigator
  
  横野知江
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Community health nursing
- Research Institution
  Niigata University
Serum carnitine kinetics by administration of fat emulsion at the perioperative period and effect of intravenous administration of L-carnitinePrincipal Investigator
- Principal Investigator
  
  Koyama Yu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Niigata University
The molecular mechanism of a lipid mediator involved in metabolic dynamics of breast cancer
- Principal Investigator
  
  Nagahashi Masayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Niigata University
Analysis of gene expression involved in the prognosis and occurrence site of gastrointestinal stromal tumors
- Principal Investigator
  
  ISHIKAWA Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Oxidative stress signaling as the molecular mechanism of chemo-resistance in esophageal cancer
- Principal Investigator
  
  KOSUGI Shin-ichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Elucidation of the mechanism of drug resistance in colorectal cancer by p62-Keap 1-Nrf2 pathway
- Principal Investigator
  
  KAMEYAMA Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma
- Principal Investigator
  
  WAKAI Toshifumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Circulating cancer cells in patients with esophageal squamous cell carcinoma : A multicenter clinical trial
- Principal Investigator
  
  KANDA Tatsuo
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
ビタミンD受容体の遺伝子多型と胃切除後骨障害に関する臨床研究Principal Investigator
- Principal Investigator
  
  小山諭
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University

All 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Intravenous Carnitine Administration in Addition to Parenteral Nutrition with Lipid Emulsion may Decrease the Inflammatory Reaction in Postoperative Surgical Patients.2017
- Author(s)
  KoyamaY, Moro K, Nakano M, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Hanyu T, Shimada Y, Jun Sakata J, Kameyama H, Kobayashi T, Wakai T.
- Journal Title
  
  Journal of Clinical Medicine Research
  
  Volume: 9 Pages: 831-837
- DOI
  10.14740/jocmr3113w
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10047
[Journal Article] Low fat-containing elemental formula is effective for postoperative recovery and potentially useful for preventing chyle leak during postoperative early enteral nutrition after esophagectomy2016
- Author(s)
  Moro K, Koyama Y, Kosugi SI, Ishikawa T, Ichikawa H, Hanyu T, Miura K, Nagahashi M, Nakajima M, Tatsuda K, Tsuchida J, Toshikawa C, Ikarashi M, Shimada Y, Sakata J, Kobayashi T, Kameyama H, Wakai T
- Journal Title
  
  Clinical Nutrition
  
  Volume: 35 Pages: 1423-1428
- DOI
  10.1016/j.clnu.2016.03.018
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10047, KAKENHI-PROJECT-16K10491
[Presentation] 乳癌細胞の代謝動態におけるスフィンゴシン-1-リン酸産生酵素の働き2017
- Author(s)
  永橋昌幸，中島真人，土田純子，諸　和樹，遠藤麻巳子，大渓彩香，庭野稔之，辰田久美子，長谷川美樹，利川千絵，五十嵐麻由子，坂田　純，亀山仁史，小林　隆，高部和明，斎藤哲也，小松雅明，曽我朋義，小山　諭，若井俊文
- Organizer
  第24回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 乳癌細胞の代謝動態におけるスフィンゴシン-1-リン酸産生酵素の働き2017
- Author(s)
  永橋昌幸，中島真人，土田純子，諸　和樹，遠藤麻巳子，大渓彩香，庭野稔之，辰田久美子，長谷川美樹，利川千絵，五十嵐麻由子，坂田　純，亀山仁史，小林　隆，高部和明，斎藤哲也，小松雅明，曽我朋義，小山　諭，若井俊文
- Organizer
  第24回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 周術期末梢静脈栄養　脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果.2017
- Author(s)
  諸　和樹, 小山　諭, 永橋　昌幸, 三浦　宏平, 土田　純子, 中島　真人, 若井　俊文.
- Organizer
  第54回日本外科代謝栄養学会
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] 乳癌および周囲微小環境では高濃度のセラミドが産生される2017
- Author(s)
  諸　和樹，永橋昌幸，遠藤麻巳子，大溪彩香，土田純子，庭野稔之，辰田久美子，長谷川美樹，利川千絵，五十嵐麻由子，中島真人，小山　諭，坂田　純，亀山仁史，小林　隆，高部和明，若井俊文
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 周術期末梢静脈栄養：脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果2017
- Author(s)
  諸　和樹、小山　諭、永橋昌幸、三浦宏平、土田純子、中島真人、若井俊文１
- Organizer
  第5４回日本外科代謝栄養学会
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター（新潟県新潟市）
- Year and Date
  2017-07-06
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] Obesity-induced Sphingosine-1-phosphate in Breast Cancer Interstitial Fluid Promotes Angiogenesis.2017
- Author(s)
  Tsuchida J, Nakajima M, Moro K, Ohtani A, Endo M, Niwano T, Tatsuda K, Toshikawa C, Hasegawa M, Ikarashi M, Koyama Y, Sakata J, Kobayashi T, Kameyama H, Wakai T, Takabe K, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 乳がんのがん細胞と宿主におけるスフィンゴシン-1-リン酸産生酵素の機能解析2017
- Author(s)
  中島　真人，永橋　昌幸，大谷　彩香，遠藤　麻已子，土田　純子，諸　和樹，庭野　稔之，山浦　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，小山　諭，坂田　純，亀山　仁史，小林　隆，若井　俊文
- Organizer
  第25回日本乳癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 精神科看護師が誤嚥性肺炎予防を目的として提供している看護ケアの実態調査2017
- Author(s)
  清野由美子，関井愛紀子，小山諭
- Organizer
  日本精神保健看護学会第27回学術集会
- Data Source
  KAKENHI-PROJECT-17K19800
[Presentation] Validity of adding intravenous carnitine to parenteral nutrition with lipid emulsion for deceasing inflammatory reaction of postoperative surgical patients.2017
- Author(s)
  Koyama Y, Moro K, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Shimada Y, Kameyama H, Kobayashi T, Wakai T
- Organizer
  39th ESPEN
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] 精神科看護師が行う摂食嚥下障害への看護ケア2017
- Author(s)
  清野由美子，関井愛紀子，小山諭
- Organizer
  第24回日本精神科看護専門学術集会
- Data Source
  KAKENHI-PROJECT-17K19800
[Presentation] Sphingosine-1-phosphate affects tumor-associated immune cells in human breast cancer patients2017
- Author(s)
  Tsuchida J, Nagahashi M, Moro K, Otani A, Endo M, Ikarashi M, Nakajima M, Koyama Y, Sakata J, Kobayashi T, Kameyama H, Yan Q, Yan L, Takabe K, Wakai T
- Organizer
  The 13th Annual Academic Surgical Congress
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] シンポジウム15 私たちが日本で行うべき乳癌研究　基礎から臨床まで日本だからこそできるトランスレーショナルリサーチの実践を目指して2017
- Author(s)
  永橋　昌幸，大渓　彩香，遠藤　麻巳子，土田　純子，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，高部　和明，若井　俊文
- Organizer
  第25回日本乳癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 肥満を伴う乳癌患者における血清スフィンゴシン-1-リン酸の定量2016
- Author(s)
  土田　純子、永橋　昌幸、遠藤　麻巳子、大溪　彩香、庭野　稔之、辰田　久美子、利川　千絵、長谷川　美樹、五十嵐　麻由子、小山　諭、高部　和明、若井　俊文
- Organizer
  第78回臨床外科学会総会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 肥満によって促進される乳癌の血管新生に対する抗スフィンゴシン-1-リン酸受容体治療2016
- Author(s)
  永橋　昌幸，大渓　彩香，遠藤　麻巳子，土田　純子，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，山田　顕光，青柳　智義，高部　和明，若井　俊文
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] Serum sphingosine-1-phosphate levels are elevated in breast cancer patients with lymph node metastasis2016
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Kazuki Moro, Toshiyuki Niwano, Kumiko Tatsuda, Chie Toshikawa, Miki Hasegawa, Yu Koyama, Takashi Kobayashi, Shin-ichi Kosugi, Hitoshi Kameyama, Hiroaki Aoki, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 11th Annual Academic Surgical Congress
- Place of Presentation
  Jacksonville, USA
- Year and Date
  2016-02-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 乳がん手術検体におけるスフィンゴリン脂質の定量2016
- Author(s)
  中島　真人，永橋　昌幸，大渓　彩香，遠藤　麻巳子，土田　純子，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，小山　諭，若井　俊文
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 周術期末梢静脈栄養における脂肪乳剤とカルニチン投与の検討2016
- Author(s)
  小山　諭、諸　和樹、永橋昌幸、三浦宏平、辰田久美子、土田純子、中島真人、若井俊文
- Organizer
  第53回日本外科代謝栄養学会
- Place of Presentation
  伊藤国際学術研究センター(東京都文京区）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] Dysregulation of Sphingolipids in Human Breast Cancer2016
- Author(s)
  Masayuki Nagahashi, Junko Tsuchida, Kazuki Moro, Toshiyuki Niwano, Kumiko Tatsuda, Chie Toshikawa, Miki Hasegawa, Yu Koyama, Takashi Kobayashi, Shin-ichi Kosugi, Hitoshi Kameyama, Hiroaki Aoki, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 11th Annual Academic Surgical Congress
- Place of Presentation
  Jacksonville, USA
- Year and Date
  2016-02-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 周術期末梢静脈栄養における脂肪乳剤とカルニチン投与の検討2016
- Author(s)
  小山　諭
- Organizer
  日本外科代謝栄養学会第53回学術集会
- Place of Presentation
  東京大学伊藤国際学術研究センター（文京区・東京都）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] Obesity increases the lipid mediator, sphingosine-1-phosphate in the tumor and tumor microenvironment, and promotes tumor progression2015
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Kazuki Moro, Kumiko Tatsuda, Yu Koyama, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  San Antonio Breast Cancer Symposium 2015
- Place of Presentation
  San Antonio, USA
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 進行再発大腸癌におけるNQO1発現の臨床的意義
- Author(s)
  亀山仁史，廣瀬雄己，佐藤　洋，山田沙季，阿部　馨，庭野稔之，岩城孝和，八木亮磨，田島陽介，中野麻恵，中野雅人，島田能史，坂田　純，小林　隆，皆川昌広，小杉伸一，小山　諭，若井俊文
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Year and Date
  2014-04-16 – 2014-04-18
- Data Source
  KAKENHI-PROJECT-26462006

1. KOSUGI Shin-ichi (90401736)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
2. WAKAI Toshifumi (50372470)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
3. NAGAHASHI Masayuki (30743918)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
4. KOMATSU Masaaki (90356254)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 小林隆 (40464010)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
6. KANDA Tatsuo (80303147)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MATSUDA Yasunobu (40334669)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. AJIOKA Yoichi (80222610)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ISHIKAWA Takashi (70586940)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. KAMEYAMA Hitoshi (40626420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 大橋学 (50345526)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 羽入隆晃 (50719705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. 市川寛 (50721875)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 廣瀬雄己 (10737365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
15. 西條康夫 (10270828)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 横野知江 (50579597)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
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41. KAWACHI Yasuyuki

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42. YABUSAKI Hiroshi

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44. TAMAGUCHI Toshikazu

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Koyama Yuu 小山 諭

KOYAMA Yu 小山 諭

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抗がん剤脱毛時の頭皮悪化が予測できるウィッグ装着型ウェアラブル端末の開発Ongoing

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感覚モダリティ変換を応用した小児がん患児の食意欲の心理量測定ツールの開発Ongoing

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乳癌ホルモン療法耐性機序における脂質メディエーター分子機構の解明および臨床的意義Ongoing

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精神科における誤嚥性肺炎予防のための連携型摂食嚥下障害ケアプログラムの開発Ongoing

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皮膚・排泄ケア認定看護師の在宅褥瘡管理コンピテンシーリストの開発Ongoing

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Serum carnitine kinetics by administration of fat emulsion at the perioperative period and effect of intravenous administration of L-carnitinePrincipal Investigator

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The molecular mechanism of a lipid mediator involved in metabolic dynamics of breast cancer

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Analysis of gene expression involved in the prognosis and occurrence site of gastrointestinal stromal tumors

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Oxidative stress signaling as the molecular mechanism of chemo-resistance in esophageal cancer

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Elucidation of the mechanism of drug resistance in colorectal cancer by p62-Keap 1-Nrf2 pathway

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Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma

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Circulating cancer cells in patients with esophageal squamous cell carcinoma : A multicenter clinical trial

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ビタミンD受容体の遺伝子多型と胃切除後骨障害に関する臨床研究Principal Investigator

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Koyama Yuu 小山諭

KOYAMA Yu 小山諭

[Presentation] 周術期末梢静脈栄養　脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果.2017

[Presentation] シンポジウム15 私たちが日本で行うべき乳癌研究　基礎から臨床まで日本だからこそできるトランスレーショナルリサーチの実践を目指して2017