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Hirose Yuki  廣瀬 雄己

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… Alternative Names

廣瀬 雄己  ヒロセ ユウキ

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Researcher Number 10737365
Other IDs
Affiliation (Current) 2022: 新潟大学, 医歯学総合研究科, 客員研究員
Affiliation (based on the past Project Information) *help 2019 – 2022: 新潟大学, 医歯学総合研究科, 客員研究員
2018 – 2020: 新潟大学, 医歯学総合病院, 特任助教
2014 – 2016: 新潟大学, 医歯学総合病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Digestive surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords
Principal Investigator
S1P / 肝細胞癌 / スフィンゴ脂質 / SphK1 / TCGA / 免疫組織化学 / セラミド / スフィンゴシン-1-リン酸 / 脈管侵襲 / 抗がん剤耐性 … More / 変異シグネチャー / 固形癌 / 塩基置換 / 遺伝子パネル検査 / mutational signature … More
Except Principal Investigator
脂質メディエーター / 食道癌 / 術前化学療法 / NQO1 / 細菌叢 / 食道外科学 / 術前補助化学療法 / 酸化ストレス / 治療抵抗性 / 大腸癌 / 抗癌剤耐性 / KRAS / Nrf2 / Keap1 / p62 / 胃癌 / 相同組換え修復 / がん遺伝子パネル検査 / 白金系抗癌剤 / homologous recombination / 癌遺伝子パネル / mutational signature / DNA二重鎖切断 / 化学療法 / ヒト共生細菌叢 / 癌遺伝子異常 / 消化器 / 伝播経路 / 薬物療法 / バイオマーカー / 体液 / 潰瘍性大腸炎 / 回腸嚢炎 / 炎症 / 腸内細菌叢 / 膵癌 / S1P / 免疫微小環境 / 膵島移植 / セラミド / 遺伝子多型 Less
  • Research Projects

    (10 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (34 People)
  •  食道癌術前化学療法の治療効果予測を目指したNQO1遺伝子多型の臨床的意義の解明

    • Principal Investigator
      石川 卓
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  変異シグネチャー解析による固形癌の塩基置換パターン分類の確立及び臨床的意義の解明Principal Investigator

    • Principal Investigator
      廣瀬 雄己
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  潰瘍性大腸炎術後回腸嚢炎の発症機序解明:腸内細菌叢および脂質メディエーターの解析

    • Principal Investigator
      亀山 仁史
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  膵癌患者の免疫微小環境における脂質メディエーター分子の役割と臨床的意義

    • Principal Investigator
      滝沢 一泰
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  セラミドによる免疫制御機構を応用した膵島移植における膵島生着延長の試み

    • Principal Investigator
      小林 隆
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  Elucidation of the interaction between human commensal bacterial flora and host genetic alterations in the digestive tract

    • Principal Investigator
      若井 俊文
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  The role of lipid mediators for lymphvascular invasion in hepatocellular carcinoma and its clinical significancePrincipal Investigator

    • Principal Investigator
      Hirose Yuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Clinical significance of defective DNA double-strand break repair pathway in gastric cancer

    • Principal Investigator
      Katada Tomohiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Oxidative stress signaling as the molecular mechanism of chemo-resistance in esophageal cancer

    • Principal Investigator
      KOSUGI Shin-ichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Elucidation of the mechanism of drug resistance in colorectal cancer by p62-Keap 1-Nrf2 pathway

    • Principal Investigator
      KAMEYAMA Hitoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University

All 2021 2020 2019 2018 2017 2016 Other

All Journal Article Presentation

  • [Journal Article] Dysregulation of sphingolipid metabolic enzymes leads to high levels of sphingosine-1-phosphate and ceramide in human hepatocellular carcinoma2021

    • Author(s)
      Miura Kohei、Nagahashi Masayuki、Prasoon Pankaj、Hirose Yuki、Kobayashi Takashi、Sakata Jun、Abe Manabu、Sakimura Kenji、Matsuda Yasunobu、Butash Ali L.、Katsuta Eriko、Takabe Kazuaki、Wakai Toshifumi
    • Journal Title

      Hepatology Research

      Volume: 51 Pages: 614-626

    • DOI

      10.1111/hepr.13625

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18K08672
  • [Journal Article] Inguinal Herniation After Living Donor Kidney Transplantation: A Case Report.2020

    • Author(s)
      Kobayashi T, Miura K, Saito K, Tasaki M, Saito K, Sakata J, Takizawa K, Katada T, Hirose Y, Yuza K, Ando T, Nagahashi M, Kameyama H, Wakai T.
    • Journal Title

      Transplant Proc

      Volume: 52 Pages: 1940-1943

    • DOI

      10.1016/j.transproceed.2020.02.131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21628
  • [Journal Article] Living donor liver transplantation for more than 30-year survived patients with native liver after Kasai operation for biliary atresia2020

    • Author(s)
      Kobayashi T, Miura K, Kubota M, Kinoshita Y, Sakata J, Takizawa K, Katada T, Hirose Y, Yuza K, Ando T, Miura Y, Nagahashi M, Kameyama H, Wakai T
    • Journal Title

      Transplantation Reports

      Volume: 5 Pages: 100052-100052

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21628
  • [Journal Article] Clinical significance of NQO1 expression in patients with advanced KRAS wild colorectal cancer2017

    • Author(s)
      Hitoshi Kameyama, Yuki Hirose, Yasunobu Matsuda, Masayuki Nagahashi, Hiroshi Ichikawa, You Sato, Saki Yamada, Shinnosuke Hotta, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Toshifumi Wakai
    • Journal Title

      Int J Clin Exp Pathol

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462006
  • [Journal Article] Prognostic significance of NQO1 expression in esophageal squamous cell carcinoma after preoperative chemotherapy with cisplatin and 5-fluorouracil followed by curative esophagectomy2016

    • Author(s)
      Ichikawa H, Kosugi S, Hirose Y, Matsuda Y, Ishikawa T, Hanyu T, Usui K, Muneoka Y, Nagahashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T
    • Journal Title

      International Journal of Clinical and Experimental Pathology

      Volume: 9 Pages: 7393-7401

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461971
  • [Presentation] 慢性炎症による癌の増殖・転移を促進する脂質メディエーター分子機構2020

    • Author(s)
      永橋 昌幸, 土田 純子, 油座 築, 諸 和樹, 根本 万里子, 廣瀬 雄己, 利川 千絵, 五十嵐 麻由子, 三浦 宏平, 田島 陽介, 市川 寛, 羽入 隆晃, 滝沢 一泰, 中島 真人, 島田 能史, 小林 隆, 坂田 純, 石川 卓, 亀山 仁史, 若井 俊文
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-20K09074
  • [Presentation] Defective Homologous Recombination in Platinum-based Chemotherapy for Gastric Cancer2019

    • Author(s)
      T. Katada, H. Ichikawa, Y. Hirose, M. Nagahashi, Y. Shimada, T. Hanyu, T. Ishikawa, Y. Kano, Y. Muneoka, J. Sakata, T. Kobayashi, H. Kameyama, T. Wakai
    • Organizer
      14th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08698
  • [Presentation] 肝細胞癌患者における脂質メディエーター・スフィンゴシン-1-リン酸及びセラミドの定量とその意義2018

    • Author(s)
      永橋 昌幸, 廣瀬 雄己, 三浦 宏平, 油座 築, 相馬 大輝, 安藤 拓也, 峠 弘治, 石川 博輔, 堅田 朋大, 坂田 純, 小林 隆, 中島 真人, 羽入 隆晃, 市川 寛, 石川 卓, 島田 能史, 亀山 仁史, 高部 和明, 若井 俊文
    • Organizer
      日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-18K08672
  • [Presentation] 大腸癌化学療法におけるNQO1発現解析の意義2016

    • Author(s)
      亀山仁史,廣瀬雄己,島田能史,八木亮磨,田島陽介,岡村拓磨,中野雅人,市川 寛,永橋昌幸,坂田 純,小林 隆,若井俊文
    • Organizer
      JDDW 2016
    • Place of Presentation
      神戸コンベンションセンター(兵庫県神戸市)
    • Year and Date
      2016-11-05
    • Data Source
      KAKENHI-PROJECT-26462006
  • [Presentation] Clinical significance of NQO1 expression in patients with KRAS wild-type unresectable colorectal cancer2016

    • Author(s)
      Hitoshi Kameyama, Yuki Hirose, Yoshifumi Shimada, Ryoma Yagi, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Masayuki Nagahashi, Takashi Kobayashi, Toshifumi Wakai
    • Organizer
      IASGO 2016
    • Place of Presentation
      Seoul (South Korea)
    • Year and Date
      2016-09-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462006
  • [Presentation] 進行再発大腸癌におけるNQO1発現の臨床的意義

    • Author(s)
      亀山仁史,廣瀬雄己,佐藤 洋,山田沙季,阿部 馨,庭野稔之,岩城孝和,八木亮磨,田島陽介,中野麻恵,中野雅人,島田能史,坂田 純,小林 隆,皆川昌広,小杉伸一,小山 諭,若井俊文
    • Organizer
      第115回日本外科学会定期学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-04-16 – 2014-04-18
    • Data Source
      KAKENHI-PROJECT-26462006
  • [Presentation] NQO1 EXPRESSION HAS PROGNOSTIC SIGNIFICANCE IN KRAS-WILD UNRESECTABLE COLORECTAL CANCER

    • Author(s)
      Y. Hirose, H. Kameyama, T. Ohashi, K. Takizawa, M. Nagahashi, T. Kobayashi, J. Sakata, T. Wakai
    • Organizer
      46th World Congress of Surgery
    • Place of Presentation
      Bangkok
    • Year and Date
      2015-08-23 – 2015-08-27
    • Data Source
      KAKENHI-PROJECT-26462006
  • 1.  若井 俊文 (50372470)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 9 results
  • 2.  永橋 昌幸 (30743918)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 10 results
  • 3.  市川 寛 (50721875)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 4.  KOSUGI Shin-ichi (90401736)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 5.  油座 築 (00745565)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 6.  坂田 純 (70447605)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 7.  島田 能史 (20706460)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 8.  KAMEYAMA Hitoshi (40626420)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 9.  小林 隆 (40464010)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 10.  三浦 宏平 (70733658)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 11.  奥田 修二郎 (00512310)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  KOMATSU Masaaki (90356254)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  石川 卓 (70586940)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 14.  羽入 隆晃 (50719705)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 15.  小山 諭 (10323966)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 16.  松田 康伸 (40334669)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 17.  竹内 志穂 (70422277)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  諸 和樹 (10745566)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  Katada Tomohiro (20815782)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  味岡 洋一 (80222610)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  西條 康夫 (10270828)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  中島 真人 (60588250)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  中野 麻恵 (20790281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  中野 雅人 (70744788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  小柳 英人 (70831725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  田島 陽介 (30757505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 27.  滝沢 一泰 (30706437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  長櫓 宏規 (90888033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  木下 義晶 (80345529)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 30.  宗岡 悠介 (00769391)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  赤澤 宏平 (10175771)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  加納 陽介 (90745580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  須貝 美佳 (10772030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  崎村 建司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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