MIYOSHI Yasuo 三好康雄

Researcher Number	50283784
Other IDs
Affiliation *help	2014 – 2018 : 兵庫医科大学, 医学部, 教授 2012 : 兵庫医科大学, 医学部, 教授 2009 : 兵庫医科大学, 医学部, 准教授 2007 : 兵庫医科大学, 医学部, 准教授 1999 – 2006 : Osaka University Medical School, Assistant Professor, 医学系研究科, 助手 1997 – 1998 : 大阪大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General surgery / Digestive surgery / General surgery Except Principal Investigator Pathological medical chemistry / General surgery / Biological Sciences / Digestive surgery / General surgery
Keywords	Principal Investigator 乳癌 / CYP3A4 / β-tubulin / BRCA2 / Predictive factor / β-catenin / leptin / DiGeorge症候群 / differential display / 易罹患性 … More Except Principal Investigator 乳癌 / 遺伝子診断 / 遺伝子発現プロファイル / 乳がん / STK11 / 化学療法感受性 / BRCA2 / Peutz-Jeghers syndrome / LKB1遺伝子 / 予後 / EB3 / PCR-SSCP法 / APCL / 微小転移 / BRCA1 / 糖転移酵素 / 遺伝性乳癌 / LKB1 / 53BP2 / Mutation search / PJS / EB1 / ATAC-PCR / DiGeorge症候群 / 甲状腺癌 / 易罹患性 / 免疫チェックポイント / ゲノム創薬 / 治療効果 / 共通欠失領域 / Mutaition search / 遺伝子発現 / Nucrinetastasis / Breast cancer / 細胞周期 / 乳癌罹患リスク / サイトカイン / VNTR / 内分泌療法耐性乳癌 / 家族性乳癌 / レドックス / APC遺伝子ファミリー / CATCH22 / ホルモン療法耐性 / βカテニン / エストロゲン受容体 / 22q11 / エストロゲン / 癌 / システムバイオロジー / 内分泌療法耐性乳がん / タキサン / ホルモン / プロファイリング / 薬剤感受性 / 細胞増殖 / WT1 mRNA / 白血病 / APCL(APC-Like) / アロマターゼ阻害剤 / ゲノム / Risk assessment / 悪性度 / 抗癌剤感受性 / Genetic diagnosis / クロストーク / アンスラサイクリン / 細胞周期プロファイリング / 免疫応答 / パクリタキセル / 蛋白質 Less

乳癌術前化学療法の治療効果における局所ならびに全身性の免疫応答の意義の解明Ongoing
- Principal Investigator
  
  今村美智子
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hyogo College of Medicine
FDG-PETによる術前化学療法の早期治療効果判定法の確立Principal InvestigatorOngoing
- Principal Investigator
  
  三好康雄
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hyogo College of Medicine
Therapeutic advances in BIG3-PHB2 inhibition targeting the cross-talk between estrogen and growth factors in breast cancer
- Principal Investigator
  
  YOSHIMARU Tetsuro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokushima
Identification and characterization of a novel unknown glycosyltransferase GTUF in breast cancer cells
- Principal Investigator
  
  MATSUO Taisuke
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Iwate Medical University
  The University of Tokushima
Drug development and biological function study of novel estrogen receptor activity modulator BIG3 protein
- Principal Investigator
  
  KATAGIRI Toyomasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Functional roles of a novel glycosyltrasnferase BCGT1 in breast cancer cells
- Principal Investigator
  
  MATSUO Taisuke
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Molecular Diagnosis of Breast Cancer Characteristics for Personalized Medicine
- Principal Investigator
  
  NOGUCHI Shinzaburo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Establishment of treatment and prevention for breast cancer by adipocytokines.Principal Investigator
- Principal Investigator
  
  MIYOSHI Yasuo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Identification of predictive factors for docetaxel in breast cancersPrincipal Investigator
- Principal Investigator
  
  MIYOSHI Yasuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
乳がんの遺伝子診断とその臨床応用
- Principal Investigator
  
  NOGUCHI Shinzaburo
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Clinical Application of Genetic Diagnosis of Breast Cancer
- Principal Investigator
  
  NOGUCHI Shinzaburo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Peutz-jeghers症候群原因遺伝子の単離
- Principal Investigator
  
  小山公美子
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
CATCH22症候群における遺伝子レベルでの発生機構の解析Principal Investigator
- Principal Investigator
  
  三好康雄
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
Isolation and characterization of Peutz-Jeghers Syndrome Gene
- Principal Investigator
  
  KOYAMA Kumiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Japanese Foundation for Cancer Research
  Osaka University
Isolation of colorectal cancer-related genes, induced by β-catenin activation.Principal Investigator
- Principal Investigator
  
  MIYOSHI Yasuo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
CATCH22症候群における遺伝子レベルでの発生機構の解析
- Principal Investigator
  
  KURAHASHI Hiroki
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University

All 2017 2016 2015 2014 2013 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor.2017
- Author(s)
  Y. Shikata Y, T. Yoshimaru, M. Komatsu, H. Katoh, R. Sato, S. Kanagaki, Y. Okazaki, S. Toyokuni, E. Tashiro, S. Ishikawa, T. Katagiri, M. Imoto,
- Journal Title
  
  Cancer Sci.
  
  Volume : 108 Pages : 785-794
- DOI
  10.1111/cas.13175
- Description
  Epub ahead of print
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-15K08398, KAKENHI-PROJECT-16H06276
[Journal Article] A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells.2017
- Author(s)
  Yoshimaru T, Ono M, Bando Y, Chen YA, Mizuguchi K, Shima H, Komatsu M, Imoto I, Izumi K, Honda J, Miyoshi Y, Sasa M, Katagiri T
- Journal Title
  
  Nature Communications
  
  Volume : 印刷中
- DOI
  10.1038/ncomms15427
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461948
[Journal Article] Stapled BIG3 helical peptide ERAP potentiates antitumour activity for breast cancer therapeutics.2017
- Author(s)
  Yoshimaru T, Aihara K, Komatsu M, Matsushita Y, Okazaki Y, Toyokuni S, Honda J, Sasa M, Miyoshi Y, Otaka A, Katagiri T
- Journal Title
  
  Scientific Reports
  
  Volume : 印刷中
- DOI
  10.1038/s41598-017-01951-6
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461948
[Journal Article] Prognostic significance of preoperative <sup>18</sup>F-FDG PET/CT for breast cancer subtypes.2016
- Author(s)
  Higuchi T, Nishimukai A, Ozawa H, Fujimoto Y, Yanai A, Miyagawa Y, Murase K, Imamura M, Takatsuka Y, Kitajima K, Fukushima K, Miyoshi Y.
- Journal Title
  
  Breast
  
  Volume : 30 Pages : 5-12
- DOI
  10.1016/j.breast.2016.08.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461963
[Journal Article] Present and future role of FDG-PET/CT imaging in the management of breast cancer.2016
- Author(s)
  Kitajima K, Miyoshi Y.
- Journal Title
  
  Jpn J Radiol.
  
  Volume : 34(3) Pages : 167-180
- DOI
  10.1007/s11604-015-0516-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461963
[Journal Article] Diagnostic and prognostic value of (18)F-FDG PET/CT for axillary lymph node staging in patients with breast cancer.2016
- Author(s)
  Kitajima K, Fukushima K, Miyoshi Y, Katsuura T, Igarashi Y, Kawanaka Y, Mouri M, Maruyama K, Yamano T, Doi H, Yamakado K, Hirota S, Hirota S.
- Journal Title
  
  Jpn J Radiol.
  
  Volume : 34(3) Pages : 220-228
- DOI
  10.1007/s11604-015-0515-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461963
[Journal Article] BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells2015
- Author(s)
  Kim NH, Yoshimaru T, Chen YA, Matsuo T, Komatsu M, Miyoshi Y, Tanaka E, Sasa M, Katagiri T
- Journal Title
  
  PLoS One.
  
  Volume : 10
- DOI
  10.1371/journal.pone.0127707
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-25293079
[Journal Article] Association between 18F-FDG uptake and molecular subtype of breast cancer.2015
- Author(s)
  Kitajima K, Fukushima K, Miyoshi Y, Nishimukai A, Hirota S, Igarashi Y, Katsuura T, Maruyama K, Hirota S.
- Journal Title
  
  Eur J Nucl Med Mol Imaging.
  
  Volume : online Pages : 1371-1377
- DOI
  10.1007/s00259-015-3070-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461963
[Journal Article] Therapeutic advances in BIG3-PHB2 inhibition targeting the crosstalk between estrogen and growth factors in breast cancer.2015
- Author(s)
  Yoshimaru T, Komatsu M, Miyoshi Y, Honda J, Sasa M, Katagiri T
- Journal Title
  
  Cancer Sci.
  
  Volume : 106 Pages : 550-558
- DOI
  10.1111/cas.12654
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-25293079
[Journal Article] Activation of mTOR/S6K But Not MAPK Pathways Might Be Associated With High Ki-67, ER+, and HER2- Breast Cancer.2015
- Author(s)
  Yanai A, Inoue N, Yagi T, Nishimukai A, Miyagawa Y, Murase K, Imamura M, Enomoto Y, Takatsuka Y, Watanabe T, Hirota S, Sasa M, Katagiri T, Miyoshi Y.
- Journal Title
  
  Clinical Breast Cancer
  
  Volume : 15 Pages : 197-203
- DOI
  10.1016/j.clbc.2014.12.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293079, KAKENHI-PUBLICLY-25134712
[Journal Article] Involvement of B3GALNT2 overexpression in the cell growth of breast cancer.2014
- Author(s)
  Matsuo T, Komatsu M, Yoshimaru T, Kiyotani K, Miyoshi Y, Sasa M, Katagiri T.
- Journal Title
  
  International Journal of Oncology
  
  Volume : 44 Pages : 427-434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860240
[Journal Article] Involvement of B3GALNT2 overexpression in the cell growth of breast cancer.2014
- Author(s)
  Matsuo T, Komatsu M, Yoshimaru T, Kiyotani K, Miyoshi Y, Sasa M, Katagiri T.
- Journal Title
  
  International Journal of Oncology
  
  Volume : 44 Pages : 427-434
- DOI
  10.3892/ijo.2013.2187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293079
[Journal Article] Xanthohumol suppresses oestrogen-signalling in breast cancer through the specific inhibition of BIG3-PHB2 interactions.2014
- Author(s)
  Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi M, Honda J, Sasa M, and Katagiri T
- Journal Title
  
  Scientific Reports
  
  Volume : 4 Pages : 7335-7335
- DOI
  10.1038/srep07355
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23102006, KAKENHI-PUBLICLY-25134712, KAKENHI-PROJECT-25293079, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-26860212, KAKENHI-PROJECT-221S0001
[Journal Article] Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.2013
- Author(s)
  Yoshimaru T, Komatsu M, Matsuo T, Chen YA, Murakami Y, Mizuguchi K, Mizohata E, Inoue T, Akiyama M, Yamaguchi R, Imoto S, Miyano S, Miyoshi Y, Sasa M, Nakamura Y, Katagiri T.
- Journal Title
  
  Nature Communications
  
  Volume : 4 Pages : 2443-2443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860240
[Journal Article] Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis2013
- Author(s)
  Komatsu M, Yoshimaru T, Matsuo T, Kiyotani K, Miyoshi Y, Tanahashi T, Rokutan K, Yamaguchi R, Saito A, Imoto S, Miyano S, Nakamura Y, Sasa M, Shimada M, Katagiri T
- Journal Title
  
  Int J Oncol
  
  Volume : 42 Pages : 478-506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790369
[Journal Article] Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.2013
- Author(s)
  T. Yoshimaru, M. Komatsu, T. Matsuo, Y.-A. Chen, Y. Murakami, K. Mizuguchi, E. Mizohata, T. Inoue, M. Akiyama, R. Yamaguchi, S. Imoto, S. Miyano, Y. Miyoshi, M. Sasa, Y. Nakamura, and T. Katagiri
- Journal Title
  
  Nature communications
  
  Volume : 4 Pages : 2433-2433
- DOI
  10.1038/ncomms3443
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24109017, KAKENHI-PUBLICLY-25134712, KAKENHI-PROJECT-25293079, KAKENHI-PROJECT-25430186
[Journal Article] Determination of the specific activity of CDK1 and CDK2 as a novel prognostic indicator for early breast cancer.2008
- Author(s)
  Kim, S.J., Nakayama, S., Miyoshi, Y., Taguchi, T., Tamaki, Y., Matsushima, T., Torikoshi, Y., Tanaka, S., Yoshida, T., Ishihara, H., Noguchi, S.
- Journal Title
  
  Ann Oncol 19
  
  Pages : 68-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Association of GSTP1 expression with resistance to docetaxel and paclitaxel in human breast cancers.2008
- Author(s)
  Arai, T., Miyoshi, Y., Kim, S.J., Akazawa, K., Maruyama, N., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Eur J Surg Oncol 34
  
  Pages : 734-738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Topoisomerase llalpha-positive and BRCA1-negative phenotype : Associationwith favorable response to epirubicin-based regimens for human breast cancers2008
- Author(s)
  Miyoshi Y., et.al.
- Journal Title
  
  Cancer Lett 264
  
  Pages : 44-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Low nuclear grade but not cell proliferation predictive of pathological complete response to docetaxel in human breast cancers2008
- Author(s)
  Miyoshi Y., et.al.
- Journal Title
  
  J Cancer Res Clin Oncol 134
  
  Pages : 561-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Topoisomerase IIalpha-positive and BRCA1-negative phenotype: Association with favorable response to epirubicin-based regimens for human breast cancers.2008
- Author(s)
  Miyoshi, Y., Kurosumi, M., Kurebayashi, J., Matsuura, N., Takahashi, M., Tokunaga, E., Egawa, C., Masuda, N., Kim, S.J., Okishiro, M., Yanagisawa, T., Ueda, S., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Cancer Lett 26
  
  Pages : 44-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Quantitative assessment of mammographic density and breast cancer risk for Japanese women.2008
- Author(s)
  Kotsuma, Y., Tamaki, Y., Nishimura, T., Tsubai, M., Ueda, S., Shimazu, K., Jin Kim, S., Miyoshi, Y., Tanji, Y., Taguchi, T., Noguchi, S.
- Journal Title
  
  Breast 17
  
  Pages : 27-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Connexin26 expression is associated with aggressive phenotype in human papillary and follicular thyroid cancers.2008
- Author(s)
  Naoi, Y., Miyoshi, Y., Taguchi, T., Kim, S.J., Arai, T., Maruyama, N., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Cancer Lett 262
  
  Pages : 248-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Low nuclear grade but not cell proliferation predictive of pathological complete response to docetaxel in human breast cancers.2008
- Author(s)
  Miyoshi, Y., Kurosumi, M., Kurebayashi, J., Matsuura, N., Takahashi, M., Tokunaga, E., Egawa, C., Masuda, N., Kim, S.J., Okishiro, M., Yanagisawa, T., Ueda, S., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  J Cancer Res Clin Oncol 134
  
  Pages : 561-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Potential of reduction in total tumor volume measured with 3D-MRI as a prognostic factor for locally-advanced breast cancer patients treated with primary chemotherapy.2008
- Author(s)
  Akazawa, K., Tamaki, Y., Taguchi, T., Tanji, Y., Miyoshi, Y., Kim, S.J., Shimazu, K., Ueda, S., Yanagisawa, T., Okishiro, N., Imazato, M., Yasuyuki, K., Sato, Y., Tamura, S., Noguchi, S.
- Journal Title
  
  Breast J 14
  
  Pages : 523-531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Growth-inhibitory effect of adiponectin via adiponectin receptor 1 on human breast cancer cells through inhibition of S-phase entry without inducing apoptosis.2008
- Author(s)
  Nakayama, S., Miyoshi, Y., Ishihara, H., Noguchi, S.
- Journal Title
  
  Breast Cancer Res Treat 112
  
  Pages : 405-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Demonstration of Adiponectin Receptors 1 and 2 mRNA expression in human breast cancer cells.2007
- Author(s)
  Takahata, C., Miyoshi, Y., Irahara, N., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Cancer Lett 250
  
  Pages : 229-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Low LATS2 mRNA level can predict favorable response to epirubicin plus cyclophosphamide, but not to docetaxel, in breast cancers.2007
- Author(s)
  Takahashi, Y., Miyoshi, Y., Morimoto, K., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  J Cancer Res Clin Oncol 133
  
  Pages : 501-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Low nuclear grade but not cell proliferation predictive of pathological complete response to docetaxel in human breast cancers2007
- Author(s)
  Miyoshi, Y., et. al.
- Journal Title
  
  J Cancer Res Clin Oncol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Clinicopathologic Analysis of Breast Cancers with PIK3CA Mutations in Japanese Women.2007
- Author(s)
  Maruyama, N., Miyoshi, Y., Taguchi, T., Tamaki, Y., Monden, M., Noguchi, S.
- Journal Title
  
  Clin Cancer Res 13
  
  Pages : 408-414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Connexin26 expression is associated with lymphatic vessel invasion and poor prognosis in human breast cancer.2007
- Author(s)
  Naoi, Y., Miyoshi, Y., Taguchi, T., Kim, S.J., Arai, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Breast Cancer Res Treat 106
  
  Pages : 11-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels2006
- Author(s)
  Miyoshi Y
- Journal Title
  
  Int J Cancer 118
  
  Pages : 1414-1419
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] High expression of ubiquitin carboxy-terminal hydrolase-L1 and -L3 mRNA predicts early recurrence in patients with invasive breast cancer2006
- Author(s)
  Miyoshi Y
- Journal Title
  
  Cancer Sci 97
  
  Pages : 523-529
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels.2006
- Author(s)
  Miyoshi, Y., et al.
- Journal Title
  
  Int J Cancer 118・6
  
  Pages : 1414-1419
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591332
[Journal Article] High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels.2006
- Author(s)
  Miyoshi, Y., Funahashi, T., Tanaka, S., Taguchi, T., Tamaki, Y., Shimomura, I., Noguchi, S.
- Journal Title
  
  Int J Cancer 118
  
  Pages : 1414-1419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Preoperative evaluation of residual tumor extent by three-dimensional magnetic resonance imaging in breast cancer patients treated with neoadjuvant chemotherapy.2006
- Author(s)
  Akazawa, K., Tamaki, Y., Taguchi, T., Tanji, Y., Miyoshi, Y., Kim, S.J., Ueda, S., Yanagisawa, T., Sato, Y., Tamura, S., Noguchi, S.
- Journal Title
  
  Breast J 12
  
  Pages : 130-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Association of GSTP1 CpG Islands Hypermethylation with Poor Prognosis in Human Breast Cancers.2006
- Author(s)
  Arai, T., Miyoshi, Y., Kim, S.J., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Breast Cancer Res Treat 100
  
  Pages : 169-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Quantitative analysis of aromatase mRNA expression derived from various promoters (I. 4, I. 3, PII and I. 7) and its association with expression of TNF-alpha, IL-6 and COX-2 mRNAs in human breast cancer.2006
- Author(s)
  Irahara, N., Miyoshi, Y., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Int J Cancer 118
  
  Pages : 1915-1921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Quantitative analysis of aromatase, sulfatase and 17beta-HSD(1) mRNA expression in soft tissue metastases of breast cancer.2006
- Author(s)
  Irahara, N., Miyoshi, Y., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Cancer Lett 243
  
  Pages : 23-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] High expression of ubiquitin carboxy-terminal hydrolase-L1 and -L3 mRNA predicts early recurrence in patients with invasive breast cancer.2006
- Author(s)
  Miyoshi, Y., Nakayama, S., Torikoshi, Y., Tanaka, S., Ishihara, H., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Cancer Sci 97
  
  Pages : 523-529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels.2006
- Author(s)
  Miyoshi Y
- Journal Title
  
  Int J Cancer 118・6
  
  Pages : 1414-1419
- Data Source
  KAKENHI-PROJECT-17591332
[Journal Article] High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels.2006
- Author(s)
  Miyoshi, Y., et al.
- Journal Title
  
  Int J Cancer volume 118, number 6
  
  Pages : 1414-1419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591332
[Journal Article] Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers.2005
- Author(s)
  Takahashi, Y., Miyoshi, Y., Takahata, C., Irahara, N., Taguchi, T., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Clin Cancer Res 11
  
  Pages : 1380-1385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Differentiation of follicular thyroid adenoma from carcinoma by means of gene expression profiling with adapter-tagged competitive polymerase chain reaction.2005
- Author(s)
  Taniguchi, K., Takano, T., Miyauchi, A., Koizumi, K., Ito, Y., Takamura, Y., Ishitobi, M., Miyoshi, Y., Taguchi, T., Tamaki, Y., Kato, K., Noguchi, S.
- Journal Title
  
  Oncology 69
  
  Pages : 428-435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] High thioredoxin expression is associated with resistance to docetaxel in primary breast cancer.2005
- Author(s)
  Kim, S.J., Miyoshi, Y., Taguchi, T., Tamaki, Y., Nakamura, H., Yodoi, J., Kato, K., Noguchi, S.
- Journal Title
  
  Clin Cancer Res 11
  
  Pages : 8425-8430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Possible involvement of aromatase overexpression induced by cyclo-oxygenase-2 in the pathogenesis of idiopathic gynecomastia.2005
- Author(s)
  Irahara, N., Miyoshi, Y., Taguchi, T., Tamaki, Y., Noguchi, S., Harada, N.
- Journal Title
  
  Endocr Res 31
  
  Pages : 219-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Prediction of Response to Docetaxel by Immunohistochemical Analysis of CYP3A4 Expression in Human Breast Cancers.2005
- Author(s)
  Miyoshi, Y., et al.
- Journal Title
  
  Breast Cancer 12
  
  Pages : 11-15
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Prediction of docetaxel response in human breast cancer by gene expression profiling.2005
- Author(s)
  Iwao-Koizumi, K., Matoba, R., Ueno, N., Kim, S.J., Ando, A., Miyoshi, Y., Maeda, E., Noguchi, S., Kato, K.
- Journal Title
  
  J Clin Oncol 23
  
  Pages : 422-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] Prediction of Response to Docetaxel by Immunohistochemical Analysis of CYP3A4 Expression in Human Breast Cancers.2005
- Author(s)
  Miyoshi, Y., Taguchi, T., Kim, S.J., Tamaki, Y., Noguchi, S.
- Journal Title
  
  Breast Cancer 12
  
  Pages : 11-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015027
[Journal Article] 肥満と乳癌2005
- Author(s)
  三好康雄, 他
- Journal Title
  
  アディポサイエンス 2・2
  
  Pages : 168-177
- Data Source
  KAKENHI-PROJECT-17591332
[Journal Article] 肥満と乳癌2005
- Author(s)
  三好康雄他
- Journal Title
  
  アデポサイエンス 2・2
  
  Pages : 168-177
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591332
[Journal Article] Prognostic significance of intra-tumoral estradiol level in breast cancer patients.2004
- Author(s)
  Miyoshi, Y., et al.
- Journal Title
  
  Cancer Lett 216
  
  Pages : 115-121
- Data Source
  KAKENHI-PROJECT-12217075
[Journal Article] Down-regulation of intratumoral aromatase messenger RNA levels by docetaxel in human breast cancers.2004
- Author(s)
  Miyoshi, Y., et al.
- Journal Title
  
  Clin Cancer Res 10
  
  Pages : 8163-8169
- Data Source
  KAKENHI-PROJECT-12217075
[Presentation] エストロゲン受容体陽性・HER2陰性乳癌のFDG-PETにおけるSUVmax値と増殖能との相関2016
- Author(s)
  井上奈都子, 樋口智子, 西向有沙, 尾澤宏美, 柳井亜矢子, 宮川義仁, 村瀬慶子, 今村美智子, 高塚雄一, 山野理子, 三好康雄.
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビッグサイト（東京）
- Data Source
  KAKENHI-PROJECT-26461963
[Presentation] FDG-PETにおけるSUVmax値のサブタイプ別予後因子としての意義2016
- Author(s)
  樋口智子, 西向有沙, 尾澤宏美, 柳井亜矢子, 宮川義仁, 村瀬慶子 ,今村美智子, 高塚雄一, 山野理子, 三好康雄．
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビッグサイト（東京）
- Data Source
  KAKENHI-PROJECT-26461963
[Presentation] Development of chemically modified peptide inhibitor ERAP targeting BIG3-PHB2 complex on hormone-resistant breast cancer2016
- Author(s)
  Tetsuro Yoshimaru, Yosuke Matsushita, Masato Komatsu, Yasumasa Okazaki, Shinya Toyokuni, Mitsunori Sasa, Yasuo Miyoshi, Toyomasa Katagiri
- Organizer
  第75回日本癌学会・学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461948
[Presentation] FDG-PET におけるSUVmax値のサブタイプ別予後因子としての意義2016
- Author(s)
  樋口智子、西向有沙、尾澤宏美、柳井亜矢子、宮川義仁、村瀬慶子、今村美智子、高塚雄一、山野理子、三好康雄
- Organizer
  第24回　日本乳癌学会学術総会
- Place of Presentation
  東京ビッグサイト（東京）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26461963
[Presentation] A novel A-kinase anchoring protein, BIG3, coordinates estrogen signalling in breast cancer cells2016
- Author(s)
  Tetsuro Yoshimaru, Masaya Ono, Kenji Mizuguchi, Yasuo Miyoshi, Mitsunori Sasa, Toyomasa Katagiri
- Organizer
  The 12th International Conference on Protein Phosphatase
- Place of Presentation
  近畿大学東大阪キャンパス 11月ホール（大阪府東大阪市）
- Year and Date
  2016-11-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461948
[Presentation] BIG3-PHB2 interaction is a key potential therapeutic target in luminal-type breast cancer2015
- Author(s)
  Tetsuro Yoshimaru, Masato Komatsu, Etsu Tashiro, Hiroyuki Osada, Masaya Imoto, Shinya Toyokuni, Yasuo Miyoshi, Mitsunori Sasa, Toyomasa Katagiri
- Organizer
  第74回日本癌学会・学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26461948
[Presentation] エストロゲン受容体制御分子BIG3を標的とした新規ER陽性乳がん治療法の開発2015
- Author(s)
  吉丸哲郎、小松正人、三好康雄、本田純子、笹三徳、片桐豊雅
- Organizer
  第72回徳島乳腺研究会
- Place of Presentation
  徳島大学病院日亜メディカルホール（徳島県徳島市）
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-26461948
[Presentation] 19S プロテアソーム構成遺伝子PAG1 の核内過剰発現はトリプルネガティブ乳癌の増殖に関与する2013
- Author(s)
  小松正人、吉丸哲郎、松尾泰佑、清谷一馬、三好康雄、笹三徳、片桐豊雅
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-25860240
[Presentation] エストロゲン受容体活性化制御分子ERAP1 と腫瘍抑制因子REAの相互作用を標的とした内分泌療法耐性乳癌の治療法の開発2013
- Author(s)
  吉丸哲郎、小松正人、松尾泰佑、三好康雄、笹三徳、中村祐輔、片桐豊雅
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-25860240
[Presentation] がん特異的糖転移酵素BCGT1 による小胞体ストレス制御を介した新規乳癌細胞増殖機構の解明2013
- Author(s)
  松尾泰佑、尾野雅哉、吉丸哲郎、小松正人、三好康雄、笹三徳、片桐豊雅
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-25860240
[Presentation] エストロゲン受容体活性化制御分子ERAP1と腫瘍抑制因子REAの相互作用を標的とした内分泌療法耐性乳癌の治療法の開発2013
- Author(s)
  吉丸哲郎, 小松正人, 松尾泰佑, 三好康雄, 笹三徳, 中村祐輔, 片桐豊雅
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-25293079
[Presentation] 悪性度の高いトリプルネガティブ乳癌における核内19S-proteasome関連遺伝子(nPAG1)の役割
- Author(s)
  小松正人、吉丸哲郎、尾野雅哉、松尾泰佑、清谷一馬、三好康雄、笹三徳、片桐豊雅
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25860240
[Presentation] New therapeutics for luminal-type breast cancer targeting BIG3-PHB2 interaction
- Author(s)
  Tetsuro Yoshimaru, Masato Komatsu, Taisuke Matsuo, Yasuo Miyoshi, Mitsunori Sasa, Yusuke Nakamura, Toyomasa Katagiri
- Organizer
  第73回日本癌学会・学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26461948

1. KOYAMA Kumiko (90294066)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
2. KATAGIRI Toyomasa (60291895)

# of Collaborated Projects : 4results

# of Collaborated Products : 22results
3. NOGUCHI Shinzaburo (10303942)

# of Collaborated Projects : 3results

# of Collaborated Products : 24results
4. TAMAKI Yasuhiro (10273690)

# of Collaborated Projects : 3results

# of Collaborated Products : 22results
5. KURAHASHI Hiroki (30243215)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. TAGUCHI Tetsuya (80243260)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. TSUKAMOTO Fumine (70303964)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. MATSUO Taisuke (70533222)

# of Collaborated Projects : 2results

# of Collaborated Products : 7results
9. ONO Masaya (00270900)

# of Collaborated Projects : 2results

# of Collaborated Products : 2results
10. BANDO Yoshimi (00238239)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
11. YOSHIMARU Tetsuro (80424729)

# of Collaborated Projects : 2results

# of Collaborated Products : 14results
12. 芝英一 (90215997)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
13. SASA Mitsunori

# of Collaborated Projects : 2results

# of Collaborated Products : 7results
14. JIN Kim Seung (90346213)

# of Collaborated Projects : 1results

# of Collaborated Products : 13results
15. TANJI Yoshio (90263269)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. MIZUGUCHI Kenji (50450896)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
17. 杉山治夫 (70162906)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. 柳井亜矢子 (00529159)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
19. 北島一宏 (80448860)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
20. 樋口智子 (50786407)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
21. 今村美智子 (50567211)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. 盛本浩二 (00599996)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
23. 藤本由希枝 (10786130)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. OKAZAKI Yasumasa

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
25. SHI Lei

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
26. IMOTO MASAYA

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
27. TASHIRO ETSU

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
28. MURAKAMI Yoichi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
29. 豊國伸哉

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
30. 伊川正人

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
31. 小松正人

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
32. 長田裕之

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
33. 中村努

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
34. 井上豪

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

MIYOSHI Yasuo 三好 康雄

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乳癌術前化学療法の治療効果における局所ならびに全身性の免疫応答の意義の解明Ongoing

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FDG-PETによる術前化学療法の早期治療効果判定法の確立Principal InvestigatorOngoing

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Establishment of treatment and prevention for breast cancer by adipocytokines.Principal Investigator

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Identification of predictive factors for docetaxel in breast cancersPrincipal Investigator

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CATCH22症候群における遺伝子レベルでの発生機構の解析Principal Investigator

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Isolation of colorectal cancer-related genes, induced by β-catenin activation.Principal Investigator

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MIYOSHI Yasuo 三好康雄