ASAKA Masahiro 浅香正博

Researcher Number	10113507
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Affiliation *help	2016 – 2018 : 北海道医療大学, その他, 学長 2000 – 2005 : 北海道大学, 大学院・医学研究科, 教授 2004 : 北海道大学, 大学院医学研究科, 教授 2000 : 北海道大学, 医学研究科, 教授 1995 – 2000 : 北海道大学, 医学部, 教授 1986 : 北海道大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Biological Sciences / Gastroenterology / Gastroenterology / 内科学一般 Except Principal Investigator Gastroenterology / Virology / Gastroenterology / Biological Sciences
Keywords	Principal Investigator 胃癌 / H.pylori / 腸上皮化生 / 萎縮性胃炎 / 胃炎 / Cag A gene / gastritis / EMR / Helicobacter pylori / H. pylori … More Except Principal Investigator 胃癌 / H.pylori / ESXR1 / CagA / K-ras / アポトーシス / SHP-2 / ヘリコバクタ・ピロリ / 転写制御 / NF-kB activation / Nod2遺伝子 / 消化性潰瘍 / オーダーメイド治療 / API2-MALT1 chimeric transcript / cancer gene therapy / NF-κB / 分子多型 / tyrosine phosphorylation / RT-PCR / ADHESION / TYPE 4 SECRETION MACHINERY / 潜伏感染遺伝子発現 / H.pylon / GASTRIC CANCER / HELICOBACTER PYLOR / 胃酸分泌 / トランスジェニックマウス / HELICOBACTER PYLORI / アジア / ヘリコバクター・ピロリ菌 / 分子多型性 / ワクチン / VACCINATION / 外膜蛋白 / NF-kB / CATALASE / Gastric MALT lymphoma / CARD15 / Epstein-Barr virus / Helicobacterpylori / 胃上皮細胞 / API2-MALT1遺伝子転座 / molecular polymorphism / H.Pylori / immunoblotting / OUTER MEMBRANE / 遺伝子治療 / 接着 / チロシンリン酸化 / ヘリコバクター属 / クローン病 / カタラーゼ / DNAアレイ / 胃マルトリンパ腫 / 4型分泌機構 Less

Helicobacter pylori感染と胃癌粘膜病変の検討 -特に胃癌との関わりPrincipal Investigator
- Principal Investigator
  
  浅香正博
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
解糖系のキー酵素であるアルドラーゼAの抑制による癌細胞発育抑制の試みPrincipal Investigator
- Principal Investigator
  
  浅香正博
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
クローン病と関連する新規ヘリコバクター属の同定
- Principal Investigator
  
  杉山敏郎
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  University of Toyama
  Toyama Medical and Pharmaceutical University
Helicobacter pylori感染と胃粘膜病変の検討 ―特に胃癌との関わり―Principal Investigator
- Principal Investigator
  
  浅香正博
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Helicobacter pylori感染と胃粘膜病変 ―特に胃癌との関わり―Principal Investigator
- Principal Investigator
  
  浅香正博
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Molecular mechanism for the development of gastric lesions by Helicobacter pylori infection
- Principal Investigator
  
  HATAKEYAMA Masanori
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  HOKKAIDO UNIVERSITY
API2-MALT1 translocation and tumorgenesis in gastric MALT lymphoma
- Principal Investigator
  
  SUGIYAMA Toshiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  HOKKAIDO UNIVERSITY
Helicobacter pyloriと胃癌粘膜病変 ―特に胃癌との関わり―Principal Investigator
- Principal Investigator
  
  浅香正博
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
ヘリコバクター感染による胃癌発症関連宿主因子の同定
- Principal Investigator
  
  杉山敏郎
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
アジアにおけるH.pylori感染と胃酸分泌および疾患特異性の関係についての研究
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Basic Research for Development of Vaccination for Gastric Cancer Prevention by Catalase of Helicobacter pylori
- Principal Investigator
  
  SUGIYAMA Toshiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  HOKKAIDO UNIVERSITY
ANALYSIS OF INTERACTION BETWEEN HELICOBACTER AND GASTRC EPITHELIAL CELLS BY YEAST TWO-HYBRID METHOD
- Principal Investigator
  
  SUGIYAMA Toshiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  HOKKAIDO UNIVERSITY
Helicobacter pylori and gastric cancerPrincipal Investigator
- Principal Investigator
  
  ASAKA Masahiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  HOKKAIDO UNIVERSITY
Helicobacter pyloriと胃癌発生との関わりについての疫学的研究Principal Investigator
- Principal Investigator
  
  浅香正博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
Helicobacter pylori and its association with gastric cancerPrincipal Investigator
- Principal Investigator
  
  ASAKA Masahiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  HOKKAIDO UNIVERSITY
Helicobacter pylori感染と胃粘膜病変発生の関連性について-胃癌との関わりを中心に-Principal Investigator
- Principal Investigator
  
  浅香正博
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
ヒト正常胃上皮細胞におけるEpstein-Barrウイルス感染と癌化機構解析
- Principal Investigator
  
  今井章介
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Hokkaido University
アルドラーゼアイソザイムの免疫化学的研究Principal Investigator
- Principal Investigator
  
  浅香正博
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Hokkaido University

All 2005 2004 2003 2002 2001

All Journal Article

[Journal Article] Intraperitoneal injection of adenovirus expressing anitisense K-ras RNA suppresses peritoneal dissemination of hamster synegeneic pancreatic cancer without systemic toxicity.2005
- Author(s)
  Miura Y, Asaka M, et al.
- Journal Title
  
  Cancer Lett. 218
  
  Pages : 53-62
- Data Source
  KAKENHI-PROJECT-16659177
[Journal Article] Long-term follow-up of chronic hepatitis B after the emergence of mutations in the hepatitis B virus polymerase region.2005
- Author(s)
  Natsuizaka M, Asaka M, et al.
- Journal Title
  
  J.Viral Hepatol. 12
  
  Pages : 154-159
- Data Source
  KAKENHI-PROJECT-16659177
[Journal Article] Progressive disappearance of anti-hepatitis B surface antigen antibody and reverse sercoversion after allogeneic hematopietic stem cell transplantation in patients with previous hepatitis B virus infection.2005
- Author(s)
  Onozawa M, Asaka M, et al.
- Journal Title
  
  Transplantation 79
  
  Pages : 616-619
- Data Source
  KAKENHI-PROJECT-16659177
[Journal Article] Pathophysiological roles of macrophage migration inhibitory factor in gastrointestinal, hepatic, and pancreatic disorders.2005
- Author(s)
  Ohkawara T, Asaka M, et al.
- Journal Title
  
  J.Gastoroenterol. 40
  
  Pages : 117-122
- Data Source
  KAKENHI-PROJECT-16659177
[Journal Article] Transgenic over-expression of macrophage migration inhibitory factor renders mice markedly more susceptible to experimental colitis.2005
- Author(s)
  Ohkawara T, Asaka M, et al.
- Journal Title
  
  Clin.Exp.Immunol. 140
  
  Pages : 241-248
- Data Source
  KAKENHI-PROJECT-16659177
[Journal Article] Side effects and good effects from new chemotherapeutic agents. Case 2. Thalidomide-induced intersitiital pneumonitis.2005
- Author(s)
  Onozawa M, Asaka M, et al.
- Journal Title
  
  J.Clin.Oncol. 23
  
  Pages : 2425-2426
- Data Source
  KAKENHI-PROJECT-16659177
[Journal Article] Helicobacter pylori and Gastric Malignacies.2004
- Author(s)
  Asaka M, et al.
- Journal Title
  
  Helicobacter 9(Suppl 1)
  
  Pages : 35-41
- Data Source
  KAKENHI-PROJECT-16024201
[Journal Article] Helicobacter pylori and Gastric Malignacies.2004
- Author(s)
  Asaka M., et al.
- Journal Title
  
  Helicobacter 37
  
  Pages : 149-157
- Data Source
  KAKENHI-PROJECT-16659177
[Journal Article] The effects of Helicobacter pylori CagA protein on the growth and survival of B lymphocytes, the origin of MALT lymphoma.2003
- Author(s)
  Umehara, S., Higashi, H., Ohnishi, N., Asaka, M, Hatakeyama, M.
- Journal Title
  
  Oncogene 22
  
  Pages : 8337-8342
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370171
[Journal Article] SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein.2002
- Author(s)
  Higashi, H., Tsutsumi, R., Muto, S., Sugiyama, T., Azuma, T., Asaka, M, Hatakeyama, M.
- Journal Title
  
  Science 295
  
  Pages : 683-686
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370171
[Journal Article] Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites.2002
- Author(s)
  Higashi, H., Tsutsumi, R., Fujita, A., Yamazaki, S., Asaka, M., Azuma, T, Hatakeyama, M.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 99
  
  Pages : 14428-14433
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370171
[Journal Article] SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein.2001
- Author(s)
  Higashi, H., Tsutsumi, R., Muto, S., Sugiyama, T., Azuma, T., Asaka, M, Hatakeyama, M.
- Journal Title
  
  Science 106747
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370171

1. SUGIYAMA Toshiro (00196768)

# of Collaborated Projects : 11results

# of Collaborated Products : 0results
2. KATO Mototsugu (60271673)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
3. AZUMA Takeshi (60221040)

# of Collaborated Projects : 2results

# of Collaborated Products : 3results
4. 今井章介 (60232592)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. 千葉勉 (30188487)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. KIKUCHI Syogo (40224901)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. AKAIKE Takaaki (20231798)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. MORIUCHI Tetsuya (20174394)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. HATAKEYAMA Masanori (40189551)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
10. 杉浦亮 (20241317)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. 藤岡利生 (90145368)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 三木一正 (70107639)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. 木下芳一 (30243306)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. 菅野健太郎 (60179116)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. 穂刈格 (70301885)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. KEIDA Yoshihide

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. OGOSHI Kazuei

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. HIRAYAMA Fumihiro

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

ASAKA Masahiro 浅香 正博

Research Projects

Research Products

Co-Researchers

Helicobacter pylori感染と胃癌粘膜病変の検討 -特に胃癌との関わりPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

解糖系のキー酵素であるアルドラーゼAの抑制による癌細胞発育抑制の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

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Principal Investigator

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Helicobacter pylori感染と胃粘膜病変の検討 ―特に胃癌との関わり―Principal Investigator

Principal Investigator

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Research Institution

Helicobacter pylori感染と胃粘膜病変 ―特に胃癌との関わり―Principal Investigator

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Helicobacter pyloriと胃癌粘膜病変 ―特に胃癌との関わり―Principal Investigator

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Helicobacter pylori and gastric cancerPrincipal Investigator

Principal Investigator

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Helicobacter pyloriと胃癌発生との関わりについての疫学的研究Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Helicobacter pylori and its association with gastric cancerPrincipal Investigator

ASAKA Masahiro 浅香正博