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HIRAMATSU Keiichi  平松 啓一

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平松 啓一

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Researcher Number 10173262
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2017: 順天堂大学, 医学部, 特任教授
2010 – 2012: 順天堂大学, 医学部, 教授
1992 – 2005: 順天堂大学, 医学部, 教授
1990 – 1991: 順天堂大学, 医学部, 助教授
1986: 東京医科歯科大学, 歯学部, 講師
Review Section/Research Field
Principal Investigator
Bacteriology (including Mycology) / 細菌学 / Biological Sciences / Bacteriology (including Mycology)
Except Principal Investigator
Bacteriology (including Mycology) / Immunology
Keywords
Principal Investigator
MRSA / SCCmec / VRSA / hetero-VRSA / 黄色ブドウ球菌 / Staphylococcus aureus / vancomycin / mecA / mecI / ゲノム … More / cell wall / SCC mec / バンコマイシン / 細胞壁 / MLST / PFGE / ペニシリン結合蛋白 / エレクトロポレ-ション / mecR1 / プロトタイプMRSA / リボタイピング / パルスフィールド / コアグラーゼ / 隔壁 / 高度耐性 / ホモ耐性 / ヘテロ耐性 / 病原性 / 塩基配列 / leukocidin / CA-MRSA / HA-MRSA / PVL / MW1941 / MW1942 / MW1941/MW1942 / 白血球溶解 / Leukocidin / バンコマイシン耐性 / ムレインモノマー / affinity trapping / 細胞集団解析 / 併用療法 / hetero- VRSA / ムレインモノアー / 疫学 / PBP / genotyping / 細胞壁合成 / peptidoglycan / teicoplanin / glycopeptide / Ccr A / Ccr B / herero-VRSA / CcrA / CcrB / ヘテロVRSA / hetoro-VRSA / resistance / ccrA / ccrB / 耐性遺伝子 / 抗生物質 / DNAアレイ / トランスクリプトーム / 耐性菌 / 肺炎 / 敗血症 / Vancomycin resistance / SCC / oriC environ / clogging of peptidoglycan / Staphylococcus haemolvticus / Whole eenome seauencine / 市中獲得型MRSA / 病院内獲得型MRSA / 一般健康児 / 健康成人 / コアグラーゼ型 / MRC-NS / 看護師 / 院内獲得型MRSA / 市中感染 / メチシリン耐性遺伝子 / ブドウ球菌 / 小児 / 健康キャリアー / フィールド調査 / Community aquired MRSA / Hospital MRSA / Healthy children / Healthy / Coagulase typing … More
Except Principal Investigator
薬剤耐性 / MRSA / 黄色ブドウ球菌 / VRSA / 表層タンパク質 / 細胞壁 / バンコマイシン / 組織接着 / フィブロネクチン / ウイルス / 白血病 / 発症機構 / 癌遺伝子 / 再構成ウイルス / 細菌 / 細胞膜 / 膜透過 / 排出ポンプ / 能動排出 / 修飾酵素 / 薬剤標的 / 薬剤 / 耐性 / 透過性 / 排出 / 膜蛋白 / 抗生物質 / 消毒薬 / 楽剤耐性 / 細菌感染 / 多剤耐性 / 病院内感染 / 膜 / 緑膿菌 / beta-ラクタマーゼ / クローニング / drug resistance / bacteria / membrane / permeability / extrusion pump / active afflux / antibiotic target / beta-lactamase / 腸内細菌 / 食物繊維 / 短鎖脂肪酸 / 制御性T細胞 / 胸腺 / Aire / GPR41 / 酪酸 / 妊娠 / Treg Less
  • Research Projects

    (15 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (30 People)
  •  Maternal high fiber diet during pregnancy and lactation influences regulatory T cell differentiation in offspring in mice

    • Principal Investigator
      NAKAJIMA Akihito
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Juntendo University
  •  Identification of novel toxin genes in CA-MRSAPrincipal Investigator

    • Principal Investigator
      HIRAMATSU Keiichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Juntendo University
  •  Elucidation and conquest of S. aureus antibiotic resistance based on the whole genome sequence informationPrincipal Investigator

    • Principal Investigator
      HIRAMATSU Keiichi
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      untendo University
  •  Observation with time of the rise and fall of community-acquired MRSA and its pathogenicinvestigationPrincipal Investigator

    • Principal Investigator
      HIRAMATSU Keiichi
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      JUNTENDO UNIVERSITY
  •  黄色ブドウ球菌の全ゲノム情報に基づく薬剤耐性機構の解明とその克服Principal Investigator

    • Principal Investigator
      平松 啓一
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
  •  バンコマイシン耐性黄色ブドウ球菌特異的表層タンパク質の感染症治療への応用

    • Principal Investigator
      BABA Tadashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Juntendo University
  •  Epidemiology of MRSA in the world and mechanism of vancomycin resistancePrincipal Investigator

    • Principal Investigator
      HIRAMATSU Keiichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Special Purpose.
    • Research Institution
      JUNTENDO UNIVERSITY
  •  Emergence of vancomycin-resistant MRSA and its countermesuresPrincipal Investigator

    • Principal Investigator
      HIRAMATSU Keiichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Juntendo University
  •  MRSA高度耐性化因子HmrA,HmrBの機能の研究Principal Investigator

    • Principal Investigator
      平松 啓一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Juntendo University
  •  黄色ブドウ球菌の細胞隔壁合成調節遺伝子のクローニングPrincipal Investigator

    • Principal Investigator
      平松 啓一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Juntendo University
  •  Involvement of bacterial membranes in drug resistance

    • Principal Investigator
      NAKAE Taiji
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Tokai University
  •  分子生物学的手法を用いたMRSAの遺伝的多様性の解析Principal Investigator

    • Principal Investigator
      平松 啓一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Juntendo University
  •  メチシリン耐性遺伝子mecAを担うブドウ球菌染色体上の挿入DNAの同定と構造決定Principal Investigator

    • Principal Investigator
      平松 啓一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Juntendo University
  •  黄色ブドウ球菌のペニシリン結合蛋白(PBP)遺伝子のクロ-ニングの試みPrincipal Investigator

    • Principal Investigator
      平松 啓一
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Juntendo University
  •  ウイルス性白血病の発症機構の解析

    • Principal Investigator
      小高 健
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo

All 2017 2006 2005 2004 Other

All Journal Article

  • [Journal Article] Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice.2017

    • Author(s)
      Nakajima, A. Kaga, N. Nakanishi, Y. Ohno, H. Miyamoto, J. Kimura, I. Hori, S. Sasaki, T. Hiramatsu, K. Okumura, K. Miyake, S. Habu, S. Watanabe, S.
    • Journal Title

      The Journal of Immunology

      Volume: 199 Pages: 3516-3524

    • DOI

      10.4049/jimmunol.1700248

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05789, KAKENHI-PROJECT-15H04747, KAKENHI-PROJECT-17H04218, KAKENHI-PROJECT-15H05344, KAKENHI-PROJECT-15K08533
  • [Journal Article] Novel Mechanism of Antibiotic Resistance Originating in Vancomycin-Intermediate Staphylococcus aureus2006

    • Author(s)
      Cui L, Iwamoto A, Lian J-Q, Neoh Hui-min, Maruyama T, Horikawa Y, Hiramatsu K.
    • Journal Title

      AAC 50

      Pages: 428-438

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Cross-resistance of vancomycin-intermediate Staphylococcus aureus to daptomycin and vancomycin.2006

    • Author(s)
      Cui L, Tominaga E, Neoh Hui-min, Hiramatsu K.
    • Journal Title

      Antimicrob Agents Chemother 50

      Pages: 1079-1082

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Susceptibilities to antiseptic agents and distribution of antiseptic-resistance genes qacA/B and smr of methicillin- resistant Staphylococcus aureus isolated in Asia during 1998 and 1999.2005

    • Author(s)
      Noguchi N, Suwa J, Narui K, Sasatsu M, Ito T, Hiramatsu K, Song JH.
    • Journal Title

      J Med Microbiol. 54

      Pages: 557-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus.2005

    • Author(s)
      Cui L, Lian JQ, Neoh HM, Reyes E, Hiramatsu K.
    • Journal Title

      Antimicrob Agents Chemother. 49

      Pages: 3404-13

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Antibacterial activity of dipropofol and related compounds.2005

    • Author(s)
      Ogata M, Tutumimoto Sato K, Kunikane T, Oka K, Seki M, Urano S, Hiramatsu K, Endo T.
    • Journal Title

      Biol Pharm Bull. 28

      Pages: 1120-2

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Genetic differentiation of methicillin-resistant Staphylococcus aureus strains from Korea and Japan.2005

    • Author(s)
      Soo Ko K, Peck KR, Sup Oh W, Lee NY, Hiramatsu K, Song JH.
    • Journal Title

      Microb Drug Resist. 11

      Pages: 279-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Structural comparison of ten serotypes of staphylocoagulases in Staphylococcus aureus.2005

    • Author(s)
      Watanabe S, Ito T, Takeuchi F, Endo M, Okuno E, Hiramatsu K.
    • Journal Title

      J Bacteriol. 187

      Pages: 3698-707

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Augmentation of the bactericidal activities of human cathelicidin CAP18/LL-37-derived antimicrobial peptides by amino acid substitutions.2005

    • Author(s)
      Nagaoka I, Kuwahara-Arai K, Tamura H, Hiramatsu K, Hirata M.
    • Journal Title

      Inflamm Res. 54

      Pages: 66-73

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Dissemination of methicillin-resistant staphylococci among healthy Japanese children.2005

    • Author(s)
      Hisata K, Kuwahara-Arai K, Yamanoto M, Ito T, Nakatomi Y, Cui L, Baba T, Terasawa M, Sotozono C, Kinoshita S, Yamashiro Y, Hiramatsu K.
    • Journal Title

      J Clin Microbiol. 43

      Pages: 3364-72

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Advance in Vancomycin Resistance : Research in Staphylococcus aureus2005

    • Author(s)
      Hiramatsu K. et al.
    • Journal Title

      Anti-infective Drug Discovery (in press)

    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Community-acquired methicillin-resistant Staphylococcus aureus,Uruguay.2005

    • Author(s)
      Ma XX, Galiana A, Pedreira W, Mowszowicz M, Christophersen I, Machiavello S, Lope L, Benaderet S, Buela F, Vincentino W, Albini M, Bertaux 0, Constenla I, Bagnulo H, Llosa L, Ito T, Hiramatsu K.
    • Journal Title

      Emerg Infect Dis.Erratum in : Emerg Infect Dis 1111

      Pages: 973-61329

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Two heterogeneously vancomycin-intermediate clinical isolates of methicillin-sensitive and methicillin-resistant Staphylococcus aureus in a Turkish university hospital : brief report of a surveillance study.2005

    • Author(s)
      Torun MM, Bahar H, Demirci M, Altas K, Bagdatli Y, Kocazeybek B, Kapi M, Hiramatsu K.
    • Journal Title

      Int J Antimicrob Agents. 26

      Pages: 508-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species.2005

    • Author(s)
      Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M, Ankai A, Baba S, Fukui S, Lee JC, Hiramatsu K.
    • Journal Title

      J Bacteriol. 187

      Pages: 7292-308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Heterogeneous vancomy cin-resistant Staphylococcus aureus (hetero-VISA) in Singapore.2005

    • Author(s)
      Sng LH, Koh TH, Wang GC, Hsu LY, Kapi M, Hiramatsu K.
    • Journal Title

      Int J Antimicrob Agents. 25

      Pages: 177-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Has vancomycin-resistant Staphylococcus aureus started going it alone?2004

    • Author(s)
      Hiramatsu K. et al.
    • Journal Title

      Lancet 364(9434)

      Pages: 565-566

    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Genetic characterization of methicillin-resistant Staphylococcus aureus.2004

    • Author(s)
      Hiramatsu K, Watanabe S, Takeuchi F, Ito T, Baba T.
    • Journal Title

      Vaccine. 22 Suppl

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Asian Network for Surveillance of Resistant Pathogens Study Group. Emergence in Asian countries of Staphylococcus aureus with reduced susceptibility to vancomycin.2004

    • Author(s)
      Song JH, Hiramatsu K, Suh JY, Ko KS, Ito T, Kapi M, Kiem S, Kim YS, Oh WS, Peck KR, Lee NY
    • Journal Title

      Antimicrob Agents Chemother 48

      Pages: 4926-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Has vancomycin-resistant Staphylococcus aureus started going it alone?2004

    • Author(s)
      Hiramatsu K, Cui L, Kuwahara-Arai K.
    • Journal Title

      Lancet. 364

      Pages: 565-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Nucleotide substitutions in Staphylococcus aureus strains, Mu50, Mu3, and N315.2004

    • Author(s)
      Ohta T, Hirakawa H, Morikawa K, Maruyama A, Inose Y, Yamashita A, Oshima K, Kuroda M, Hattori M, Hiramatsu K, Kuhara S, Hayashi H.
    • Journal Title

      DNA Res. 29

      Pages: 51-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC.2004

    • Author(s)
      Ito T, Ma XX, Takeuchi F, Okuma K, Yuzawa H, Hiramatsu K.
    • Journal Title

      Antimicrob Agents Chemother 48

      Pages: 2637-51

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] Genetic characterization of methicillin-resistant Staphylococcus aureus.2004

    • Author(s)
      Hiramatsu K. et al.
    • Journal Title

      Vaccine 22

    • Data Source
      KAKENHI-PROJECT-14021113
  • [Journal Article] The pore-forming activities of Leukocidin/hemolysin toxin family proteins

    • Author(s)
      Isamu HONGO, Miki MATSUO , Shinya MIYAZAKI , Chikara KAITO, Teruyo ITO, Kazuhisa SEKIMIZU, and Keiichi HIRAMATSU
    • Journal Title

      MW1941 and MW1942 of community-acquired MRSA strain, MW2. Submitted to Microbes and Infection

    • Data Source
      KAKENHI-PROJECT-22590403
  • 1.  KURODA Makoto (80317411)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  BABA Tadashi (30317458)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  KUWAHARA Kyoko (10167976)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  HANAKI Hideaki (60286747)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  ITO Teruyo (10095763)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NAKAE Taiji (50102851)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  GOTOH Naomasa (30121560)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YAMAGUCHI Akihito (60114336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  INOUE Matsuhisa (10008336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IYOBE Shizuko (90008318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SASAKI Kazumi (90276478)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  CUI Longzhu (50306932)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YAMAMOTO Munetaka (50338414)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAKAJIMA Akihito (30439294)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  OKUMURA Ko (50009700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  HABU Sonoko (30051618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  MIYAKE Sachiko (50266045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  WATANABE Sumio (20138225)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  NAKANISHI Yumiko (10614274)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  OHNO Hiroshi (50233226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  HORI Shohei (50392113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  小高 健 (00012691)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  竹森 利忠 (60114295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  甲斐 一成 (60085628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  石本 秋稔 (50073127)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  井川 洋二 (40085618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  河野 恵 (10057292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  堀 典子 (50245700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KONDO Noriko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  木村 郁夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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