YAMAGUCHI Akihito 山口明人

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YAMAGUCHI AKIHITO 山口明人

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Researcher Number	60114336
Other IDs
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Affiliation (based on the past Project Information) *help	2007 – 2011: Osaka University, 産業科学研究所, 教授 1995 – 2005: Osaka Univ.Inst.Indst.Sci., Professor, 産業科学研究所, 教授 1996: 大阪大学, 産業化学研究所, 教授 1991 – 1995: 千葉大学, 薬学部, 助教授 1987: 千葉大学, 薬学部, 助教授 1986: Faculty of Pharmaceutical Sciencies, Chiba University, 薬学部, 講師
Review Section/Research Field	Principal Investigator Structural biochemistry / Biological pharmacy / Molecular biology / Biological pharmacy / 分子細胞生物学 / Biological Sciences / Bacteriology (including Mycology) Except Principal Investigator Bacteriology (including Mycology)
Keywords	Principal Investigator アンチポーター / テトラサイクリン / テトラサイクリン排出蛋白 / 薬剤排出蛋白 / 多剤耐性 / 部位特異変異導入 / 薬剤耐性 / site-directed mutagenesis / 異物排出蛋白 / 膜輸送 … More / 薬剤排出 / 異物排出タンパク / 多剤排出タンパク / AcrB / 異物排出トランスポーター / テトラサイクリン耐性 / tetracycline / multidrug resistance / NEM / トポロジー / 構造決定 / X線結晶構造解析 / 発現制御 / インドール / マイクロアレイ / 逆輸送 / antiporter / drug efflux / antiport / drug resistance / 多剤排出蛋白 / NorA / MexAB / TetK / TetB / 耐性菌 / Cys走査変異 / ポストゲノム / xenobiotic exporter / efflux / X-ray crystallography / 多剤排出 / 能動輸送 / トランスポーター / イオンチャンネル / プロトン輸送 / H^+アンチポーター / ヒスチジン残基 / ナトリウム / プロトンアンチポート / イオンチャネル / K^+ / 立体構造モデル / 膜蛋白高次構造 / 部位特異的化学修飾 / Cys走査変異体 / 膜蛋白 / 結晶化 / 膜タンパク質結晶構造 / ペリスタポンプ機構 / マルチサイト結合 / 環境センシング / 構造解析 / 機能的回転機構 / ペリスタルティック機構 / 構造生物学 / 異物排出 / サルモネラ / 発現誘導機構 / 膜蛋白質結晶構造 / AcrAB / 抗生物質耐性 / 膜蛋白質 / 遺伝子工学 / 薬剤排出ポンプ / アンチポ-ト / 大腸菌 / tetracycline efflux protein / antibiotic resistance / membrane protein / gene engineering / 二次性能動輸送体 / 阻害剤 / スクリーニング / 緑膿菌 / 黄色ぶどう球菌 / 黄色ブドウ球菌 / inhibitor / multidrug exporter / screening / Cys走査異変 / 部位特異化学修飾 / 基質特異性 / xenobiotic efflux pump / tetracycline resistance / multidrug efflux proteins / Cys-scanning mutagenesis / topology / site-directed chemical modification / 排出 / 排出蛋白 / X線結晶解析 / cMOAT / Acr / ABCトランスポーター / Tet(B) / exporter / post genome / X線結晶構造 / 異物認識 / 結晶構造 / フェニルアラニンクラスタ / 基質結合型結晶 / 部位特異的変異導入 / フェニルアラニンクラスター / 膜タンパク質 / RND / 分子構造 / Xenobiotic exporter / X-ray crystal structure / multidrug efflux / membrane transport / active transporter / xenobiotic recognition / 発現調節 / 二成分情報伝達系 / 病原性 / 結晶構造解析 / 二成分情報伝達 / クオラムセンシング / β-ラクタム耐性 / TolC / 核様体タンパク / 強制発現 / 遺伝子ライブラリ / 排出タンパク / 発現ライブラリ / transporter / two-component signal transduction / expression regulation system / indole / pathogenicity / 反転膜小胞 / 再構成膜 / バクテリオロドプシン / 排出系 / counter transport / inside-out membrane vesicle / reconstituted membrane / bacteriorhodopsin / resistant cell … More Except Principal Investigator テトラサイクリン / クローニング / 耐性 / 抗生物質 / 共役物質輸送 / Na^+ / H^+アンチポーター / H^+ / ジペプチドシンポーター / Band 3 / アラニンキャリアー / バクテリオロドプシン / K^+-ATPase / イオン輸送 / H^+-アンチポーター / ジペプチド輸送系 / H^+ヘキソース共輸送 / テトラサイクリン排出タンパク質 / H^+ーアンチポーター / 酸性アミノ酸輸送系 / K^+ーATPase / イオン / トランスポータ / チャネル / 構造と機能 / シンポータ / アンチポ-タ / 能動的排出 / マグネシウム排出 / コバルト排出 / 反転膜小胞 / 大腸菌 / TnIO / 熱帯薬用植物 / 医薬品開発 / 薬用植物成分 / 薬理作用 / 生理活性物質 / 抗微生物活性 / 医薬品製剤 / アルカロイド / 医薬品開発の基礎研究 / 有効成分の分離方法 / 薬用植物成分の化学構造 / 生物活性物質の探索 / Tropical and medical plants / Development of medicines / Compounds of medical plants / Pharmacological effect / Biological active substance / Antimicrobial activity / Pharmaceuticals / Alkaloid / 薬剤耐性 / 細菌 / 細胞膜 / 膜透過 / 排出ポンプ / 能動排出 / 修飾酵素 / 薬剤標的 / 薬剤 / 透過性 / 排出 / 膜蛋白 / 消毒薬 / 楽剤耐性 / 細菌感染 / 多剤耐性 / 病院内感染 / MRSA / 膜 / 緑膿菌 / beta-ラクタマーゼ / drug resistance / bacteria / membrane / permeability / extrusion pump / active afflux / antibiotic target / beta-lactamase Less

Structures, functions, regulations and physiological roles of xenobiotic exportersPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Akihito
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
Studies on the crystal structure of antiporters for organic compounds and the mechanismsPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Akihito
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Post-Genomic Approach to Bacterial Xenobiotic Exporter Gene Resources and Investigation of Novel Drug Resistance Mechanisms of BacteriaPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Akihito
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Osaka University
テトラサイクリン排出蛋白の結晶構造解析Principal Investigator
- Principal Investigator
  
  山口明人
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
Molecular Basis and Physiological Roles of Xenobiotic ExportersPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Akihito
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
部位特異的化学修飾による膜蛋白質高次構造の決定Principal Investigator
- Principal Investigator
  
  山口明人
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
テトラサイクリン/H^+アンチポーターのプロトン輸送機構とイオンチャンネル機能Principal Investigator
- Principal Investigator
  
  山口明人
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
膜輸送蛋白高次構造の解明Principal Investigator
- Principal Investigator
  
  山口明人
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Studies on the Bacterial Xenobiotic Efflux MechanismPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Akihito
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
イオン駆動型トランスポーターとチャネルの構造・機能協関
- Principal Investigator
  
  土屋友房
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
テトラサイクリン/H^+アンチポーターのプロトン輸送機構とイオンチャンネル機能Principal Investigator
- Principal Investigator
  
  山口明人
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Development of the Screening System for Inhibitors of Bacterial Drug ExportersPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Akihito
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
  Chiba University
Involvement of bacterial membranes in drug resistance
- Principal Investigator
  
  NAKAE Taiji
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokai University
Studies on the Molecular Structure and Function of Tetracycline Efflux ProteinPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Akihito
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  CHIBA UNIVERSITY
イオン・溶質輸送と共役ネットワーク
- Principal Investigator
  
  川喜田正夫
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Basic study on development of medicines from tropical plants
- Principal Investigator
  
  HIROSE Seiyu
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Studies on the Bacterial Tetracyclin/H^+ Antiport Mechanisms using Site-directed MutagenesisPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Akihito
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子細胞生物学
- Research Institution
  CHIBA UNIVERSITY
大腸菌テトラサイクリン排出系のエネルギー共役機構
- Principal Investigator
  
  SAWAI Tetsuo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
STUDIES ON ACTIVE TRANSPORT CARRIER OF TETRACYCLINE IN RESISTANT ESCHERICHIA COLI USING RECONSTITUTED MEMBRANE CONTAINING BACTERIORHODOPSIPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI AKIHITO
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University

All 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 Other

All Journal Article Presentation Book Patent

[Book] 化学療法学.医療のあるべき姿を見据えて.[抗生物質最前線]2010
- Author(s)
  山口明人
- Total Pages
  315
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-19109002
[Book] トランスポーター科学最前線-フロンティアサイエンスへの招き-2008
- Author(s)
  山口明人
- Total Pages
  384
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-19109002
[Book] トランスポーター科学最前線-フロンティアサイエンスへの招き-2008
- Author(s)
  山口明人, 他分担執筆
- Total Pages
  374
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-19109002
[Book] タンパク質科学構造・物性・機能2005
- Author(s)
  山口明人 (分担執筆)
- Total Pages
  579
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-13854012
[Book] タンパク質科学構造・物性・機能(編集者:後藤祐児、桑島邦博、谷澤克行)2005
- Author(s)
  山口明人(分担執筆)
- Total Pages
  579
- Publisher
  化学同人
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Book] タンパク質科学構造・物性・機能2005
- Author(s)
  山口明人(分担執筆)
- Total Pages
  579
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-13142205
[Book] タンパク質科学構造・物性・機能(編集者 : 後藤祐児、桑島邦博、谷澤克行)2005
- Author(s)
  山口明人(分担執筆)
- Total Pages
  579
- Publisher
  化学同人
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] 多剤耐性細菌の異物排出タンパク質のしくみを解明2012
- Author(s)
  山口明人、中島良介
- Journal Title
  
  月刊化学
  
  Volume: 2 Pages: 74-74
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] A microfluidic device for simple and rapid evaluation of multidrug efflux pump inhibitors2012
- Author(s)
  Iino R, Nishino K, Noji H, Yamaguchi A, Matsumoto Y
- Journal Title
  
  frontiers in MICROBIOLOGY
  
  Volume: 3(in press)
- DOI
  10.3389/fmicb.2012.00040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Antibacterial and antifungal activities of new acylated derivatives of epigallocatechin gallate2012
- Author(s)
  Matsumoto Y, Kaihatsu K, Nishino K, Ogawa M, Kato N, Yamaguchi A
- Journal Title
  
  frontiers in MICROBIOLOGY
  
  Volume: 3(in press)
- DOI
  10.3389/fmicb.2012.00053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Roles of Salmonella multidrug efflux pumps in tigecycline resistance2011
- Author(s)
  T.Horiyama, E.Nikaido, A.Yamaguchi, K.Nishino
- Journal Title
  
  The Journal of Antimicrobial Chemotherapy
  
  Volume: 66 Pages: 105-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Effect of overexpression of small non-coding DsrA RNA on multidrug efflux in Escherichia coli2011
- Author(s)
  K.Nishino, S.Yamasaki, M.Hayashi-Nishino, A.Yamaguchi
- Journal Title
  
  The Journal of Antimicrobial Chemotherapy
  
  Volume: 66 Pages: 291-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Evaluation of multidrug efflux pump inhibitors by a new method using microfluidic channels2011
- Author(s)
  Matsumoto Y, Hayama K, Sakakihara S, Nishino K, Noji H, Iino R, Yamaguchi A
- Journal Title
  
  PLoS One
  
  Volume: 6
- DOI
  10.1371/journal.pone.0018547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Roles of Salmonella multidrug efflux pumps in tigecycline resistance2011
- Author(s)
  Horiyama T., Nikaid E., Yamaguchi A., Nishino K.
- Journal Title
  
  J. Antimicrob. Chemother.
  
  Volume: vol.66 Pages: 105-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Small RNAによる多剤耐性制御2011
- Author(s)
  西野邦彦、山崎聖司、西野-林美都子、山口明人
- Journal Title
  
  日本化学療法学会雑誌
  
  Volume: 59 Pages: 1-7
- NAID
  10027817029
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Regulation of AcrAB multidrug efflux pump in Salmonella enterica serovar Typhimurium in response to indole and paraquat2011
- Author(s)
  E.Nikaido, I.Shirosaka, A.Yamaguchi, K.Nishino
- Journal Title
  
  Microbiology
  
  Volume: 158 Pages: 648-655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY7202011
- Author(s)
  Hisano Y., Kobayashi N., Kawahara A., Yamaguchi A., Nishi T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: vol.286 Pages: 1758-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar Typhimurium2011
- Author(s)
  Yamasaki S, Nagasawa S, Hayashi-Nishino M, Yamaguchi A, Nishino K
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 64 Pages: 433-437
- DOI
  10.1038/ja.2011.28
- NAID
  10030639300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket2011
- Author(s)
  Nakashima R, Sakurai K, Yamasaki S, Nishino K, Yamaguchi A
- Journal Title
  
  Nature
  
  Volume: 480 Pages: 565-569
- DOI
  10.1038/nature10641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket2011
- Author(s)
  Nakashima R., Sakurai K., Yamasaki S., Nishino K., Yamaguchi A.
- Journal Title
  
  Nature
  
  Volume: vol.480 Pages: 565-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Effect of overexpression of small non-coding DsrA RNA on multidrug efflux in Escherichia coli2011
- Author(s)
  Nishino K., Yamasaki S., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  J. Antimicrob. Chemother.
  
  Volume: vol.66 Pages: 291-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Impact of RNA chaperone Hfq on multidrug resistance in Escherichia coli2010
- Author(s)
  J.Yamada, S.Yamasaki, H.Hirakawa, M.Hayashi-Nishino, A.Yamaguchi, K.Nishino
- Journal Title
  
  Journal of Antimicrobial Chemotherapy
  
  Volume: 65 Pages: 853-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Effect of NlpE overproduction on multidrug resistance in Escherichia coli2010
- Author(s)
  Nishino K., Yamasaki Y., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  Antimicrob. Agents Chemother.
  
  Volume: vol.54 Pages: 2239-2243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Indole enhances acid resistance in Escherichia coli2010
- Author(s)
  H.Hirakawa, M.Hayashi-Nishino, A.Yamaguchi, K Nishino
- Journal Title
  
  Microbial Pathogenesis
  
  Volume: 49 Pages: 90-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY7202010
- Author(s)
  Y.Hisano, N.Kobayashi, A.Kawahara, A.Yamaguchi, T.Nishi
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286 Pages: 1758-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Macrophage ABCA5 deficiency influences cellular cholesterol efflux and increases susceptibility to atherosclerosis in female LDLr knockout mice2010
- Author(s)
  Ye D, Meurs I, Ohigashi M, Calpe-Berdiel L, Habets KL, Zhao Y, Kubo Y, Yamaguchi A, Van Berkel TJ, Nishi T, Van Eck M
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 395 Pages: 387-394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Effect of NlpE overproduction on multidrug resistance in Escherichia coli2010
- Author(s)
  K.Nishino, S.Yamasaki, M.Hayashi-Nishino, A.Yamaguchi
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 54 Pages: 2239-2243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium2010
- Author(s)
  Horiyama T., Yamaguchi A., Nishino K.
- Journal Title
  
  J. Antimicrob. Chemother.
  
  Volume: vol.65 Pages: 1372-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Impact of RNA chaperone Hfq on multidrug resistance in Escherichia coli2010
- Author(s)
  Yamada J., Yamasaki S., Hirakawa H., Hayashi-Nishino M., Yamaguchi A., Nishino K.
- Journal Title
  
  J. Antimicrob. Chemother.
  
  Volume: vol.65 Pages: 853-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium2010
- Author(s)
  T.Horiyama, A.Yamaguchi, K Nishino
- Journal Title
  
  Journal of Antimicrobial Chemotherapy
  
  Volume: 65 Pages: 1372-1376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] A subdomain of the endoplasmic reticulum forms a cradle for autophago someformation2010
- Author(s)
  Hayashi-Nishino M., Fujita N., Noda T., Yamaguchi A., Yoshimori T., Yamamoto A.
- Journal Title
  
  Nature cell Biology 11
  
  Pages: 1433-1437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF2009
- Author(s)
  Nishino K., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  Antimicrob Agents Chemother. 53
  
  Pages: 3541-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] スフィンゴシン-1-リン酸の輸送体Spns2は心臓前駆細胞の移動を制御よる2009
- Author(s)
  川原敦雄、西毅、山口明人、望月直樹
- Journal Title
  
  細胞工学 28
  
  Pages: 390-391
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors2009
- Author(s)
  A. Kawahara, T. Nishi, Y. Hisano, H. F., A. Yamaguchi, N. Mochizuki
- Journal Title
  
  Science 323
  
  Pages: 524-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Secreted indole serves as a signal for expression of type III secretion system translocators in enterohaemorrhagic Escherichia coli O157 : H72009
- Author(s)
  H. Hirakawa, T. Kodama, A. Takumi-Kobayashi, T. Honda, A. Yamaguchi
- Journal Title
  
  Microbiology 155
  
  Pages: 541-550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Regulation and physiological function of multidrug efflux pumps in Escherichia coli and Salmonella2009
- Author(s)
  Nishino K., Nikaido E., Yamaguchi A.
- Journal Title
  
  Biochim.Biophys.Acta-Proteins and Proteomics 1794
  
  Pages: 834-843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Characterization of the ATP-dependent sphingosine-1-phosphate transporter in rat erythrocytes, Kobayashi2009
- Author(s)
  N., Kobayashi N., Yamaguchi A., Nishi T.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 21192-21200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF2009
- Author(s)
  Nishino K., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  Antimicrob. Agents Chemother 53
  
  Pages: 3541-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] トランスポーターによる多剤認識の構造的基礎2009
- Author(s)
  山口明人, 中島良介
- Journal Title
  
  遺伝子医学MOOK12創薬研究者必見! 最新トランスポーター研究2009 12
  
  Pages: 61-66
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors2009
- Author(s)
  Kawahara A., Nishi T., Hisano Y., Fukui H., Yamaguchi A., Mochizuki N.
- Journal Title
  
  Science 323
  
  Pages: 524-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors2009
- Author(s)
  Kawahara A., Nishi T., Hisano Y., Fukui H., Yamaguchi A., Mochizuki N.
- Journal Title
  
  scuence
  
  Volume: vol.323 Pages: 524-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF2009
- Author(s)
  Nishino K., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  Antimicrob Agents Chemother.
  
  Volume: vol.53 Pages: 3541-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Role of the AraC/XylS family regulator YdeO in multidrug resistance of Escherichia coli2009
- Author(s)
  Nishino K., Senda Y., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  J.Antibiot. 62
  
  Pages: 251-257
- NAID
  10030635180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Characterization of the ATP-dependent sphingosine-1-phosphate transporter in rat erythrocytes2009
- Author(s)
  Kobayashi N., Kobayashi N., Yamaguchi A., Tsuyoshi N.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 21192-21200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Regulation mechanism of Salmonella AcrAB-TolC xenobiotic transport system in response to bacterial metabolites2008
- Author(s)
  Eiji Nikaido, Kunihiko Nishino and Akihito Yamaguchi
- Journal Title
  
  Journal of the Pharmaceutical Society of Japan 128
  
  Pages: 27-28
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Rapid detection of drug efflux from single bacterial cell enclosed in femtoliter chamber array2008
- Author(s)
  Ryota Iino, Kunihiko Nishino, Masayoshi Nakata, Eiji Nikaido, Yoshimi Matsumoto, Syoichi Sakakihara, Syoji Takeuchi, Akihito Yamaguchi and Hiroyuki Noji
- Journal Title
  
  Micro Total Analysis Systems 1
  
  Pages: 757-759
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Physiological functions of drug efflux systems in Gram-negative bacteria : Their roles in bacterial drug resistance and virulence2008
- Author(s)
  K. Nishino, A. Yamaguchi
- Journal Title
  
  Jaoanese Jouanal Chemotherapy 56
  
  Pages: 443-452
- NAID
  10022594782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] AcrS/EnvR Represses the Expression of the acrAB Multidrug Efflux Genes in Escherichia coli2008
- Author(s)
  H. Hirakawa, A. Takumi-Kobayashi, U. Theisen, T. Hirata, K. Nishino, A. Yamaguchi
- Journal Title
  
  Journal of Bacteriology 190
  
  Pages: 6276-6279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] 異物排出タンパクのメカニズム2008
- Author(s)
  山口明人
- Journal Title
  
  感染・炎症・免疫 37
  
  Pages: 106-115
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] 細菌の異物排出タンパク2008
- Author(s)
  山口明人
- Journal Title
  
  日本細菌学雑誌 63
  
  Pages: 437-446
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] シナプス終末の内膜系を3Dで見る2008
- Author(s)
  西野一林美都子, 山口明人
- Journal Title
  
  細胞工学別冊電子顕微鏡で読み解く生命のなぞ
  
  Pages: 107-113
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] AcrAB Multidrug Efflux Pump Regulationin Salmonella enterica serovar Typhimurium by RamA in Response to Environmental Signals2008
- Author(s)
  Nikaido E., Yamaguchi A., Nishino K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: vol.283 Pages: 24245-24253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Virulence and Drug Resistance Roles of Multidrug Efflux Pumps in Escherichia coli and Salmonella2008
- Author(s)
  K. Nishino, A. Yamaguchi
- Journal Title
  
  Bioscience and Microflora 27
  
  Pages: 75-85
- NAID
  10021956022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] The AraC-family regulator GadX enhances multidrug resistance of Escherichia coli by activating expression of the mdtEF multidrug efflux genes2008
- Author(s)
  Kunihiko Nishino, Yasuko Senda and Akihito Yamaguchi
- Journal Title
  
  Journal of Infection and chemotherapy 14
  
  Pages: 23-29
- NAID
  10021193134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] AcrAB Multidrug Efflux Pump Regulation in Salmonella enterica serovar Typhimurium by RamA in Response to Environmental Signals2008
- Author(s)
  E. Nikaido, A. Yamaguchi, K. Nishino
- Journal Title
  
  The Journal of Biological Chemistry 283
  
  Pages: 24245-24253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] CRP regulator modulates multidrug resistance of Escherichia coli by repressing expression of the mdtEF multidrug efflux genes2008
- Author(s)
  Kunihiko Nishino, Yasuko Senda and Akihito Yamaguchi
- Journal Title
  
  The Journal of Antibiotics (in press)
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Identification of a spermidine excretion protein complex (MdtJI) in Esch erichia coli2008
- Author(s)
  Kyohei Higashi, Hiroyuki Ishigure, Risa Demizu, Takeshi Uemura, Kunihiko Nishino, Akihito Yamaguchi, Keiko Kashiwagi and Kazuei Igarashi
- Journal Title
  
  Journal of Bacteriology 190
  
  Pages: 872-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] AcrAB Multidrug Efflux Pump Regulation in Salmonella enterica serovar Typhimurium by RamA in Response to Environmental Signals2008
- Author(s)
  Nikaido E., Yamaguchi A., Nishino K.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 24245-24253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Regulation of multidrug efflux systems involved in multidrug and metal resistance of Salmonella enterica serovar Typhimurium2008
- Author(s)
  Kunihiko Nishino, Eiji Nikaido and Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 189
  
  Pages: 9066-9075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] 大腸菌の異物排出トランスポーターAcrBの構造と異物認識機構2008
- Author(s)
  村上聡、山口明人
- Journal Title
  
  生化学 79
  
  Pages: 542-549
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Tissue specific expression of the splice variants of the mouse vacuolar proton-translocating ATPase a4 subunit2008
- Author(s)
  Kawasaki-Nishi Shoko, Yamaguchi Akihito, Forgac Michael and Nishi Tsuyoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications 364
  
  Pages: 1032-1036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Role of Xenobiotic Transporters in Bacterial Drug Resistance and Virulence (Review)2008
- Author(s)
  Kunihiko Nishino and Akihito Yamaguchi
- Journal Title
  
  IUBMB Life (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Regulation of multidrug efflux systems involved in multidrug and metal resistance of Salmonella enterica serovar Typhimurium2007
- Author(s)
  Nishino K., Nikaido E., Yamaguchi A.
- Journal Title
  
  J.Bacteriol. 189
  
  Pages: 9066-9075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner2006
- Author(s)
  Nobuyoshi Kobayashi, Tsuyoshi Nishi, Takahiro Hirata, Akio Kihara, Takamitsu Sano, Yasuyuki Igarashi, Akihito Yamaguchi
- Journal Title
  
  Journal of Lipid Research 47
  
  Pages: 614-621
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner2006
- Author(s)
  Nobuyoshi Kobayashi, Tsuyoshi Nishi, Takahiro Hirata, Akio Kihara, Takamitsu Sano, Yasuyuki Igarashi, Akihito Yamaguchi
- Journal Title
  
  Journal of Lipid Research 47
  
  Pages: 614-621
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Genome-Wide analyses of Escherichia coli gene expression responsive to the BaeSR two-component regulatory system2005
- Author(s)
  Kunihiko Nishino, Takeshi Honda, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 187
  
  Pages: 1763-1772
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Genome-Wide analyses of Escherichia coli gene expression responsive to the BaeSR two-component regulatory system2005
- Author(s)
  Kunihiko Nishino, Takeshi Honda, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 187
  
  Pages: 1763-1772
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Indole induces the expression of multidrug exporter genes in Escherichia coli2005
- Author(s)
  Hidetada Hirakawa, Yoshihiko Inazumi, Takeshi Masaki, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Molecular Microbiology 55
  
  Pages: 1113-1126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] ABCA5 resides in lysosomes and ABCA5 knockout mice develop lysosomal disease-like symptoms.2005
- Author(s)
  Kubo, Y., S.Sekiya, M.Ohigashi, C.Takenaka, K.Tamura, S.Nada, T.Nishi, A.Yamamoto, A.Yamaguchi.
- Journal Title
  
  Molecular and Cellular Biology (in press)
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms2005
- Author(s)
  Yoshiyuki Kubo, Sayaka Sekiya, Megumi Ohigashi, Chiemi Takenaka, Kyoko Tamura, Shigeyuki Nada, Tsuyoshi Nishi, Akitsugu Yamamoto, Akihito Yamaguchi
- Journal Title
  
  Molecular and Cellular Biology 25
  
  Pages: 4138-4149
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms2005
- Author(s)
  Yoshiyuki Kubo, Sayaka Sekiya, Megumi Ohigashi, Chiemi Takenaka, Kyoko Tamura, Shigeyuki Nada, Tsuyoshi Nishi, Akitsugu Yamamoto, Akihito Yamaguchi
- Journal Title
  
  Molecular and Cellular Biology 25
  
  Pages: 4138-4149
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Indole induces the expression of multidrug exporter genes in Escherichia coil.2005
- Author(s)
  Hirakawa, H., Y.Inazumi, T.Masaki, T.Hirata, A.Yamaguchi
- Journal Title
  
  Molecular Microbiology 55
  
  Pages: 1113-1126
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Direct interaction of multidrug efflux transporter AcrB and outer membrane channel To1C detected via site-directed disulfide cross-linking2005
- Author(s)
  Norihisa Tamura, Satoshi Murakami, Yoshiaki Oyama, Masaji Ishiguro, Akihito Yamaguchi
- Journal Title
  
  Biochemistry 44
  
  Pages: 11115-11121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] ABCA5 resides in lysosomes and ABCA5 knockout mice develop lysosomal disease-like symptoms.2005
- Author(s)
  Kubo, Y., S.Sekiya, M.Ohigashi, C.Takenaka, K.Tamura, S.Nada, T.Nishi, A.Yamamoto, A.Yamaguchi.
- Journal Title
  
  Molecular and Cellular Biology (in press)
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking2005
- Author(s)
  Norihisa Tamura, Satoshi Murakami, Yoshiaki Oyama, Masaji Ishiguro, Akihito Yamaguchi
- Journal Title
  
  Biochemistry 44
  
  Pages: 11115-11121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Genome-Wide analyses of Escherichia coil gene expression responsive to the BaeSR two-component regulatory system.2005
- Author(s)
  Nishino, K., T.Honda, A.Yamaguchi.
- Journal Title
  
  Journal of Bacteriology 187
  
  Pages: 1763-1772
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Indole induces the expression of multidrug exporter genes in Esche richia coli.2005
- Author(s)
  Hirakawa, H., Y.Inazumi, T.Masaki, T.Hirata, A.Yamaguchi.
- Journal Title
  
  Molecular Microbiology 55
  
  Pages: 1113-1126
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Indole induces the expression of multidrug exporter genes in Escherichia coli2005
- Author(s)
  Hidetada Hirakawa, Yoshihiko Inazumi, Takeshi Masaki, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Molecular Microbiology 55
  
  Pages: 1113-1126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Genome-Wide analyses of Escherichia coli gene expression responsive to the BaeSR two-component regulatory system.2005
- Author(s)
  Nishino, K., T.Honda, A.Yamaguchi.
- Journal Title
  
  Journal of Bacteriology 187
  
  Pages: 1763-1772
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Extramembrane central pore of multidrug exporter AcrB in Escherichia coil plays an important role in drug transport.2004
- Author(s)
  Murakami, S., N.Tamura, A.Saito, T.Hirata, A.Yamaguchi.
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 3743-3748
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Extramembrane central pore of multidrug exporter AcrB in Escherichia coli plays an important role in drug transport2004
- Author(s)
  Satoshi Murakami, Norihisa Tamura, Asami Saito, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  The Journal of Biological Chemistry 279
  
  Pages: 3743-3748
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Membrane protein crystallization using laser irradiation2004
- Author(s)
  Hiroaki Adachi, Satoshi Murakami, Ai Niino, Hiroyoshi Matsumura, Kazufumi Takano, Tsuyoshi Inoue, Yusuke Mori, Akihito Yamaguchi, Takatomo Sasaki
- Journal Title
  
  Japanese Journal of Applied Physics 43
- NAID
  10013744655
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Effects of efflux transporter genes on susceptibility of Escherichia coli to tigecycline(GAR-936).2004
- Author(s)
  Hirata, T., A.Saito, K.Nishino, N.Tamura, A.Yamaguchi.
- Journal Title
  
  Antimicrobial Agents Chemotherapy 48
  
  Pages: 2179-2184
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Extramembrane central pore of multidrug exporter AcrB in Escherichia coli plays an important role in drug transport2004
- Author(s)
  Satoshi Murakami, Norihisa Tamura, Asami Saito, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  The Journal of Biological Chemistry 279
  
  Pages: 3743-3748
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Membrane protein crystallization using laser irradiation2004
- Author(s)
  Hiroaki Adachi, Satoshi Murakami, Ai Niino, Hiroyoshi Matsumura, Kazufumi Takano, Tsuyoshi Inoue, Yusuke Mori, Akihito Yamaguchi, Takatomo Sasaki
- Journal Title
  
  Japanese Journal of Applied Physics 43
- NAID
  10013744655
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Extramembrane central pore of multidrug exporter AcrB in Escherichia coil plays an important role in drug transport.2004
- Author(s)
  Murakami, S., N.Tamura, A.Saito, T.Hirata, A.Yamaguchi.
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 3743-3748
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Effects of efflux transporter genes on susceptibility of Escherichia coil to tigecycline (GAR-936).2004
- Author(s)
  Hirata, T., A.Saito, K.Nishino, N.Tamura, A.Yamaguchi.
- Journal Title
  
  Antimicrobial Agents Chemotherapy 48
  
  Pages: 2179-2184
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Role of histone-like protein H-NS in multidrug resistance o Escherichia coli2004
- Author(s)
  Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 186
  
  Pages: 1423-1429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Role of histone-like protein H-NS in multidrug resistance of Escherichia coli2004
- Author(s)
  Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 186
  
  Pages: 1423-1429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Effects of efflux transporter genes on susceptibility of Escherichia coli to Tigecycline (GAR-936)2004
- Author(s)
  Takahiro Hirata, Asami Saito, Kunihiko Nishino, Norihisa Tamur, Akihito Yamaguchi
- Journal Title
  
  Antimicrob. Agents Chemother. 48
  
  Pages: 2179-2184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Effects of efflux transporter genes on susceptibility of Escherichia coli to Tigecycline (GAR-936)2004
- Author(s)
  Takahiro Hirata, Asami Saito, Kunihiko Nishino, Norihisa Tamura, Akihito Yamaguchi
- Journal Title
  
  Antimicrob.Agents Chemother. 48
  
  Pages: 2179-2184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Multidrug-exporting secondary transporters2003
- Author(s)
  Satoshi Murakami, Akihito Yamaguchi
- Journal Title
  
  Current Opinion in Structural Biology 13
  
  Pages: 443-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Membrane topology of ABC-type macrolide antibiotic exporter MacB in Escherichia coli2003
- Author(s)
  Nobuyoshi Kobayashi, Kunihiko Nishino, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  FEBS Letter 546
  
  Pages: 241-246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Global analysis of genes regulated by EvgA of the two-component regulatory system in Escherichia coli2003
- Author(s)
  Kunihiko Nishino, Yoshihiko Inazumi, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 185
  
  Pages: 2667-2672
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Mechanisms of drug/H^+ antiport : complete cysteine-scanning mutagenesis and the protein engineering approach2003
- Author(s)
  Norihisa Tamura, Satoko Konishi, Akihito Yamaguchi
- Journal Title
  
  Current Opinion in Chemical Biology 7
  
  Pages: 570-579
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] beta-Lactam resistance modulated by the overexpression o response regulators of two-component signal transduction systems in Escherichia coli2003
- Author(s)
  Hidetada Hirakawa, Kunihiko Nishino, Junko Yamada, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Journal of Antimicrobial Chemotherapy 52
  
  Pages: 576-582
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Cloning of rat ABCA7 and its preferential expression in platelets2003
- Author(s)
  Mari Sasaki, Yoshiyuki Kubo, Shigeyuki Nada, Akihito Yamaguchi
- Journal Title
  
  Biochemical and Biophysical Research Communications 304
  
  Pages: 777-782
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Global analysis of genes regulated by EvgA of the two-component regulatory system in Escherichia coli2003
- Author(s)
  Kunihiko Nishino, Yoshihiko Inazumi, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 185
  
  Pages: 2667-2672
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Comprehensive studies of drug resistance mediated by overexpression of response regulators of two-component signal transduction systems in Escherichia coli2003
- Author(s)
  Hidetada Hirakawa, Kunihiko Nishino, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 185
  
  Pages: 1851-1856
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] beta-Lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli2003
- Author(s)
  Hidetada Hirakawa, Kunihiko Nishino, Junko Yamada, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Journal of Antimicrobial Chemotherapy 52
  
  Pages: 576-582
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Comprehensive studies of drug resistance mediated by overexpression of response regulators of two-component signal transduction systems in Escherichia coli2003
- Author(s)
  Hidetada Hirakawa, Kunihiko Nishino, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 185
  
  Pages: 1851-1856
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Membrane topology of ABC-type macrolide antibiotic exporter MacB in Escherichia coli2003
- Author(s)
  Nobuyoshi Kobayashi, Kunihiko Nishino, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  FEBS Letter 546
  
  Pages: 241-246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Cloning of rat ABCA7 and its preferential expression in platelets2003
- Author(s)
  Mari Sasaki, Yoshiyuki Kubo, Shigeyuki Nada, Akihito Yamaguchi
- Journal Title
  
  Biochemical and Biophysical Research Communications 304
  
  Pages: 777-782
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Roles of TolC-dependent multidrug transporters of Escherichia coli in resistance to beta-lactams2003
- Author(s)
  Kunihiko Nishino, Junko Yamada, Hidetada Hirakawa, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 47
  
  Pages: 3030-3033
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Roles of To1C-dependent multidrug transporters of Escherichia col in resistance to beta-lactams2003
- Author(s)
  Kunihiko Nishino, Junko Yamada, Hidetada Hirakawa, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 47
  
  Pages: 3030-3033
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Multidrug-exporting secondary transporters2003
- Author(s)
  Satoshi Murakami, Akihito Yamaguchi
- Journal Title
  
  Current Opinion in Structural Biology 13
  
  Pages: 443-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Mechanisms of drug/H^+ antiport : complete cysteine-scanning mutagenesis and the protein engineering approach2003
- Author(s)
  Norihisa Tamura, Satoko Konishi, Akihito Yamaguchi
- Journal Title
  
  Current Opinion in Chemical Biology 7
  
  Pages: 570-579
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] EvgA of the two-component signal transduction system modulates production of the YhiUV multidrug transporter in Escherichia coli2002
- Author(s)
  Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 184
  
  Pages: 2319-2323
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Membrane topology of a multidrug efflux transporter, AcrB in Escherichia coli2002
- Author(s)
  Erika Fujihira, Norihisa Tamura, Akihito Yamaguchi
- Journal Title
  
  Journal of Biochemistry (Tokyo) 131
  
  Pages: 145-151
- NAID
  10010645229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Crystal structure of the bacterial multidrug efflux transporter AcrB2002
- Author(s)
  Satoshi Murakami, Ryosuke Nakashima, Eiki Yamashita, Akihito Yamaguchi
- Journal Title
  
  Nature 419
  
  Pages: 587-593
- NAID
  10012663441
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] The putative response regulator BaeR stimulates multidrug resistance of Escherichia coil via a novel multidrug exporter system, MdtABC2002
- Author(s)
  Satoshi Nagakubo, Kunihiko Nishino, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 184
  
  Pages: 4161-4167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Crystal structure of the bacterial multidrug efflux transporter AcrB2002
- Author(s)
  Satoshi Murakami, Ryosuke Nakashima, Eiki Yamashita, Akihito Yamaguchi
- Journal Title
  
  Nature 419
  
  Pages: 587-593
- NAID
  10012663441
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] EvgA of the two-component signal transduction system modulates production of the YhiUV multidrug transporter in Escherichia coil2002
- Author(s)
  Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 184
  
  Pages: 2319-2323
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC2002
- Author(s)
  Satoshi Nagakubo, Kunihiko Nishino, Takahiro Hirata, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 184
  
  Pages: 4161-4167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Membrane topology of a multidrug efflux transporter, AcrB in Escherichia coli2002
- Author(s)
  Erika Fujihira, Norihisa Tamura, Akihito Yamaguchi
- Journal Title
  
  Journal of Biochemistry(Tokyo) 131
  
  Pages: 145-151
- NAID
  10010645229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Complete cysteine-scanning mutagenesis and site-directed chemical modification of the Tn10-encoded metal-tetracycline/H^+ antiporter2001
- Author(s)
  Norihisa Tamura, Satoko Konishi, Shinobu Iwaki, Tomomi Kimura-Someya, Shigeyuki Nada, Akihito Yamaguchi
- Journal Title
  
  The Journal of Biological Chemistry 276
  
  Pages: 20330-20339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Novel macrolide-specific ABC-type efflux transporter in Escherichia coil2001
- Author(s)
  Nobuyoshi Kobayashi, Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 183
  
  Pages: 5639-5644
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Complete cysteine-scanning mutagenesis and site-directed chemical modification of the Tn10-encoded metal-tetracycline/H^+ antiporter2001
- Author(s)
  Norihisa Tamura, Satoko Konishi, Shinobu Iwaki, Tomomi Kimura-Someya, Shigeyuki Nada, Akihito Yamaguchi
- Journal Title
  
  The Journal of Biological Chemistry 276
  
  Pages: 20330-20339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Overexpression of the response regulator evgA of the two-component signal transduction system modulates multidrug resistance conferred by multidrug resistance transporters2001
- Author(s)
  Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 183
  
  Pages: 1455-1458
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Type II topoisomerase mutations in fluoroquinolone-resistant clinical strains of Pseudomonas aeruginosa isolated in 1998 and 1999 : role of target enzyme in mechanism of fluoroquinolone resistance2001
- Author(s)
  Takaaki Akasaka, Mayumi Tanaka, Akihito Yamaguchi, Kenichi Sato
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 45
  
  Pages: 2263-2268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Overexpression of the response regulator evgA of the two-component signal transduction system modulates multidrug resistance conferred by multidrug resistance transporters2001
- Author(s)
  Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 183
  
  Pages: 1455-1458
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Monoclonal antibody that binds to the central loop of the Tn10-encoded metal tetracycline/H^+ antiporter of Escherichia coli2001
- Author(s)
  Shigeyuki Nada, Satoshi Murakami, Shizuka Okamoto, Yoshiyuki Kubo, Akihito Yamaguchi
- Journal Title
  
  Journal of Biochemistry (Tokyo) 129
  
  Pages: 87-91
- NAID
  130003534056
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Analysis of a complete library of putative drug transporter genes in Escherichia coli2001
- Author(s)
  Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 183
  
  Pages: 5803-5812
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Type II topoisomerase mutations in fluoroquinolone-resistant clinical strains of Pseudomonas aeruginosa isolated in 1998 and 1999 : role of target enzyme in mechanism of fluoroquinolone resistance2001
- Author(s)
  Takaaki Akasaka, Mayumi Tanaka, Akihito Yamaguchi, Kenichi Sato
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 45
  
  Pages: 2263-2268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Journal Article] Novel macrolide-specific ABC-type efflux transporter in Escherichia coli2001
- Author(s)
  Nobuyoshi Kobayashi, Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 183
  
  Pages: 5639-5644
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Analysis of a complete library of putative drug transporter genes in Escherichia coli2001
- Author(s)
  Kunihiko Nishino, Akihito Yamaguchi
- Journal Title
  
  Journal of Bacteriology 183
  
  Pages: 5803-5812
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Monoclonal antibody that binds to the central loop of the Tn10-encoded metal tetracycline/H^+ antiporter of Escherichia coli2001
- Author(s)
  Shigeyuki Nada, Satoshi Murakami, Shizuka Okamoto, Yoshiyuki Kubo, Akihito Yamaguchi
- Journal Title
  
  Journal of Biochemistry(Tokyo) 129
  
  Pages: 87-91
- NAID
  130003534056
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Journal Article] Impact of RNA chaperone Hfq on Multidrug resistance in Escherichia coli
- Author(s)
  Yamada J., Yamasaki S., Hirakawa H., Hayashi-Nishino M., Yamaguchi A., Nishino K.
- Journal Title
  
  J.Antimicrob.Chemother. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Journal Article] Effect of NlpE overproduction on multidrug resistance in Escherichia coli
- Author(s)
  Nishino K., Yamasaki S., Hayashi-Nishino M., Yamaguchi A.
- Journal Title
  
  Antimicrob.Agents Chemother. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109002
[Patent] 細菌または真菌の抗菌薬感受性の検査方法およびそれに用いるシステム2011
- Inventor(s)
  松本佳巳、葉山浩平、榊原昇一、西野邦彦、山口明人、野地博行、飯野亮太
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Industrial Property Number
  2011-200036
- Filing Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-19109002
[Patent] スフィンゴシン1-リン酸の新規トランスポーター分子2008
- Inventor(s)
  望月直樹、川原敦雄、西毅、山口明人
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団/国立大学法人大阪大学
- Industrial Property Number
  2008-245177
- Filing Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19109002
[Patent] スフィンゴシン1-リン酸の新規トランスポーター分子2008
- Inventor(s)
  望月直樹, 川原敦雄, 西毅, 山口明人
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団
- Industrial Property Number
  2008-245177
- Filing Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19109002
[Patent] L-システイン生産菌及びL-システインの製造法2004
- Inventor(s)
  高木博史, 中森茂, 山口明人, 西野邦彦
- Industrial Property Rights Holder
  味の素株式会社
- Industrial Property Number
  2004-103652
- Filing Date
  2004-03-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13854012
[Patent] L-システイン生産菌及びL-システインの製造法2004
- Inventor(s)
  高木博史, 中森茂, 山口明人, 西野邦彦
- Industrial Property Rights Holder
  味の素株式会社
- Industrial Property Number
  2004-103652
- Filing Date
  2004-03-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142205
[Presentation] Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket2012
- Author(s)
  Seiji Yamasaki, Ryosuke Nakashima, Keisuke Sakurai, Kunihiko Nishino, Akihito Yamaguchi
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Outer Membrane Permeabilizing Effects of Phe-Arg-β-Naphthylamide on Pseudomonas aeruginosa2012
- Author(s)
  Yoshimi Matsumoto, Kunihiko Nishino, Akihito Yamaguchi
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 外膜透過性亢進薬としてのPhe-Arg-β-naphtylamide (PAN)2012
- Author(s)
  松本佳巳, 西野邦彦, 山口明人
- Organizer
  第46回緑膿菌感染症研究会
- Place of Presentation
  東京
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Immuno-Electron Tomography for Elucidation of Localization of the Mutidrug Efflux Pump in Salmonella2012
- Author(s)
  Mitsuko Hayashi-Nishino, Akihito Yamaguchi, Kunihiko Nishino
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Mechanism of multidrug recognition by the RamR regulatory protein required for the induction of the AcrAB multidrug efflux pump2012
- Author(s)
  S.Yamasaki, E.Nikaido, K.Sakurai, R.Nakashima, A.Yamaguchi, K.Nishino
- Organizer
  The 15th SANKEN International Symposium 2012, The 10th SANKEN Nanotechnology Symposium
- Place of Presentation
  大阪
- Year and Date
  2012-01-12
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Peristaltic Mechanism of Multidrug Efflux Transporter AcrB Revealed by the Crystal Structure of AcrB with High-Molecular-Weight Drugs2011
- Author(s)
  Nakashima R., Sakurai K., Yamasaki S., Nishino K., Yamaguchi A.
- Organizer
  7th Handai Nanoscience and Nanotechnology International Symposium
- Place of Presentation
  大阪
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 多剤耐性サルモネラ異物排出トランスポーターAcrB発現制御機構の解析2011
- Author(s)
  山崎優、二階堂英司、城阪郁江、櫻井啓介、中島良介、山口明人、西野邦彦
- Organizer
  産業科学研究第67回学術講演会
- Place of Presentation
  大阪
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar typhimurium2011
- Author(s)
  Seiji Yamasaki, Saya Nagasawa, Mitsuko Hayashi-Nishino, Akihito Yamaguchi, Kunihiko Nishino
- Organizer
  国際微生物学連盟2011(IUMS 2011)会議/第84回日本細菌学会総会
- Place of Presentation
  北海道
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Functional network of multi-component drug efflux systems in Salmonella enterica serovar typhimurium2011
- Author(s)
  Yamasaki, S., S.Nagasawa, M.Hayashi-Nishino, A.Yamaguchi, K.Nishino
- Organizer
  The 14^<th> SANKEN international symposium
- Place of Presentation
  ロイヤルオークホテル、大津
- Year and Date
  2011-01-25
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] The Reguration of the AcrAB multidrug efflux pump in Salmonella2011
- Author(s)
  Suguru Yamasaki, nikaido eiji, Keisuke Sakurai, Ryousuke Nakashima, Akihito Yamaguchi, Kunihiko Nishino
- Organizer
  France 4th Symposium on Antimicrobial Resistance in Animals and the Environment
- Place of Presentation
  France
- Year and Date
  2011-06-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 排出ポンプ阻害剤Phe-Arg-ss-naphtylamide (PAN)の作用メカニズム2011
- Author(s)
  松本佳巳、葉山浩平、飯野亮太、西野邦彦、野地博行、山口明人
- Organizer
  第45回緑膿菌感染症研究会
- Place of Presentation
  仙台、宮城
- Year and Date
  2011-02-04
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Small RNAによる細菌多剤耐性化メカニズムの解明2011
- Author(s)
  山崎聖司、西野-林美都子、山口明人、西野邦彦
- Organizer
  第84回日本生化学大会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Peristaltic mechanism of multidrug efflux transport2011
- Author(s)
  Akihito Yamaguchi, Ryosuke Nakashima, Keisuke Sakurai, Seiji Yamasaki, Kunihiko Nishino
- Organizer
  FRANCE-JAPAN WORKSHOP, Bio-inspired approaches : Micro-& Nano-Architectures, Materials & Imaging
- Place of Presentation
  France
- Year and Date
  2011-10-11
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Streptococcus pneumoniaeの自然免疫回避におけるPfbAの役割2011
- Author(s)
  山口雅也、寺尾豊、西野邦彦、山口明人、浜田茂幸、川端重忠
- Organizer
  第3回口腔環境制御研究カテゴリー集会
- Place of Presentation
  長崎
- Year and Date
  2011-02-04
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Development of novel therapeutic strategies to tackle multidrug-resistant pathogens2011
- Author(s)
  Nishino, K., S.Yamasaki, M.Hayashi-Nishino, A.Yamaguchi
- Organizer
  The American Association for the Advancement of Science (AAAS) 2011 Annual Meeting
- Place of Presentation
  Washington, DC, U.S.A.
- Year and Date
  2011-02-20
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 多剤耐性サルモネラ異物排出トランスポーターAcrB発現制御因子RamRと基質との相互作用解析2011
- Author(s)
  山崎優, 二階堂英司, 櫻井啓介, 中島良介, 山口明人, 西野邦彦
- Organizer
  第5回細菌学若手コロッセウム
- Place of Presentation
  高知
- Year and Date
  2011-08-10
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 生物はいかにして異物を認識するか2011
- Author(s)
  山口明人
- Organizer
  産業科学研究第67回学術講演会
- Place of Presentation
  大阪
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] マイクロデバイスを用いた簡易迅速多剤耐性緑膿菌(MDRP)検出法2011
- Author(s)
  葉山浩平、松本佳巳、西野邦彦、山口明人
- Organizer
  第59回日本化学療法学会西日本支部総会/第54回日本感染症学会中日本地方会学術集会
- Place of Presentation
  奈良
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrB発現制御ネットワーク解析2011
- Author(s)
  山崎優, 二階堂英司, 城阪郁江, 櫻井啓介, 中島良介, 山口明人, 西野邦彦
- Organizer
  第84回日本生化学大会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Function of mammalian sphingosin 1-phosphate transporter2011
- Author(s)
  Nishi, T., Hisano, Y., Kawasaki-Nishi, S., Yamaguchi, A.
- Organizer
  The 14^<th> SANKEN international symposium
- Place of Presentation
  ロイヤルオークホテル、大津
- Year and Date
  2011-01-25
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 排出ポンプ阻害薬と外膜透過性亢進薬の有用性2011
- Author(s)
  松本佳巳、西野邦彦、山口明人
- Organizer
  第59回日本化学療法学会総会
- Place of Presentation
  札幌
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] マイクロデバイスを用いた迅速多剤耐性緑膿菌(MDRP)検出法2011
- Author(s)
  葉山浩平、松本佳巳、西野邦彦、山口明人
- Organizer
  第58回日本化学療法学会東日本支部総会/第60回日本感染症学会東日本地方学術集会合同学会
- Place of Presentation
  山形
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Structural basis of multidrug efflux2011
- Author(s)
  Yamaguchi A.
- Organizer
  The 80th Anniversary Commemoration of Osaka University International Symposium Series
- Place of Presentation
  Hampshire Hotel-Plaza(Groningen, The Netherlands)(招待講演)
- Year and Date
  2011-06-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Antibiotic Augmenting Activities of Phe-Arg-β-Naphthylamide Based on its Membrane Permeabilizing Effects2011
- Author(s)
  Y.Matsumoto, K.Nishino, A.Yamaguchi
- Organizer
  51st Interscience Conference on Antimicrobial Agents and Chemotherapy(ICAAC)
- Place of Presentation
  U.S.A.
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Effect of efflux pump inhibition versus outer membrane permeabilization to antimicrobial activities of ciprofloxacin and erythromycin against Pseudomonas aeruginosa2011
- Author(s)
  Y.MATSUMOTO, K.NISHINO, A.YAMAGUCHI
- Organizer
  国際微生物学連盟2011(IUMS 2011)会議/第84回日本細菌学会総会
- Place of Presentation
  北海道
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Structural basis of multidrug efflux2011
- Author(s)
  Akihito Yamaguchi
- Organizer
  The 80th Anniversary Commemoration of Osaka University International Symposium Series
- Place of Presentation
  Netherlands(招待)
- Year and Date
  2011-06-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Deveropment of novel therapeutic strategies to tackle multidrug-resistant pathogens2011
- Author(s)
  Mitsuko Hayashi-Nishino, Ryosuke Nakashima, Keisuke Sakurai, Akihito Yamaguchi, Kunihiko Nishino
- Organizer
  FRANCE-JAPAN WORKSHOP, Bio-inspired approaches : Micro-& Nano-Architectures, Materials & Imaging
- Place of Presentation
  France
- Year and Date
  2011-10-11
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ薬物排出トランスポーターの生理機能解析2011
- Author(s)
  大野愛子、尾島学、西野美都子、山口明人、西野邦彦
- Organizer
  第33回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  岡山
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 生物による異物認識の原点:異物排出タンパクの構造に見る異物認識原理2011
- Author(s)
  山口明人
- Organizer
  第3回知の拠点セミナー
- Place of Presentation
  東京(招待)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 新たな共結晶構造から明らかになった多剤排出タンパクAcrBの多剤認識機構2011
- Author(s)
  山崎聖司, 中島良介, 櫻井啓介, 西野邦彦, 山口明人
- Organizer
  第64回日本細菌学会関酉支部総会
- Place of Presentation
  大阪
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 細菌異物排出トランスポーターの機能解析2011
- Author(s)
  山崎聖司、中島良介、櫻井啓介、西野邦彦、山口明人
- Organizer
  第33回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  岡山
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 異物排出タンパクAcrBに存在する基質結合マルチサイトの解明2011
- Author(s)
  櫻井啓介、中島良介、山崎聖司、西野邦彦、山口明人
- Organizer
  平成23年度日本結晶学会年会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 排出タンパクによる異物認識機構-最新の知見2011
- Author(s)
  山口明人
- Organizer
  第33回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  岡山(招待)
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Immuno-electron tomography for elucidation of localization of the mutidrug efflux pumps in Salmonella2011
- Author(s)
  Mitsuko Hayashi-Nishino, Akihito Yamaguchi, Kunihiko Nishino
- Organizer
  7th Handai Nanoscience and Nanotechnology International Symposium
- Place of Presentation
  大阪
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 大腸菌を用いた緑膿菌のRND型排出ポンプMexABおよびMexXYの活性測定2010
- Author(s)
  松本佳巳、葉山浩平、飯野亮太、西野邦彦、野地博行、山口明人
- Organizer
  第42回緑膿菌感染症研究会
- Place of Presentation
  東京
- Year and Date
  2010-02-12
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Analysis of the mammalian sphingosine 1-phosphate transporters2010
- Author(s)
  Nishi T., Hisano Y., Kobayashi N., Yamaguchi A.
- Organizer
  The 27th Naito Conference, Membrane Dynamics and Lipid Biology[I]
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrABの発現制御に関与するRamRの解析2010
- Author(s)
  二階堂英司、櫻井啓介、中島良介、城阪郁江、山口明人、西野邦彦
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Streptococcus pneumoniaeは赤血球に侵入し好中球免疫を回避する2010
- Author(s)
  山口雅也、寺尾豊、八木哲也、西野邦彦, 山口明人、川端重忠
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Overexpressed Lipoprotein Increases Multidrug Resistance by Induction of Multidrug Transporters in E.coli2010
- Author(s)
  S.Yamasaki, M.Hayashi-Nishino, A.Yamaguchi, K.Nishino
- Organizer
  American Society for Microbiology 110th General Meeting
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2010-05-25
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Structural basis of multidrug recognition2010
- Author(s)
  Yamaguchi A.
- Organizer
  Nanofair 2010-8th International Nanotechnology Symposium
- Place of Presentation
  International Congress Center(Dresden, Germany)(招待講演)
- Year and Date
  2010-07-06
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 大腸菌薬剤排出ポンプ制御におけるNlpEの役割2010
- Author(s)
  山崎聖司、西野美都子、山口明人、西野邦彦
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] スフィンゴシン1リン酸輸送体の同定と機能解析2010
- Author(s)
  西毅、小林直木、久野悠、川原敦雄、山口明人
- Organizer
  日本生体エネルギー研究会第35回討論会
- Place of Presentation
  北海道
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 大腸菌多剤耐性化におけるRNAシャペロンHfqの役割2010
- Author(s)
  山崎聖司、山田純子、平川秀忠、西野美都子、山口明人、西野邦彦
- Organizer
  第22回微生物シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Functional analysis of novel S1P transporter, Spns22010
- Author(s)
  Hisano, Y., Yamaguchi, A., Nishi T.
- Organizer
  The 27th Naito Conference, Membrane Dynamics and Lipid Biology[I]
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Electron Tomography Revealed the Endoplasmic Reticulum as a Source of Autophagosomal Membranes2010
- Author(s)
  M.Hayashi-Nishino, N.Fujita, T.Noda, A.Yamaguchi, K.Nishino, T.Yoshimori, A.Yamamoto
- Organizer
  American Society for Microbiology 110th General Meeting
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2010-05-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrAB発現制御メカニズムの解析2010
- Author(s)
  二階堂英司、櫻井啓介、中島良介、城阪郁江、山口明人、西野邦彦
- Organizer
  第22回微生物シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrAB発現制御因子RamRの構造機能解析2010
- Author(s)
  二階堂英司、櫻井啓介、中島良介、城阪郁江、山口明人、西野邦彦
- Organizer
  平成22年度日本結晶学会年会
- Place of Presentation
  大阪大学コンベンションセンター
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Sphingoshine 1-Phosphate Efflux Transporter2010
- Author(s)
  Akihito Yamaguchi
- Organizer
  The 27th Naito Conference, Membrane Dynamics and Lipid Biology[I]
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Effects of NlpE overproduction on the induction of xenobiotic transporters involved in multidrug resistance in Escherichia coli2010
- Author(s)
  Yamasaki S., Nishino-Hayashi M., Yamaguchi A., Nishino K.
- Organizer
  The 13th SANKEN International Symposium
- Place of Presentation
  大阪
- Year and Date
  2010-01-18
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 免疫抑制剤FTY720の作用機序におけるS1P輸送体SPNS2の役割2010
- Author(s)
  久野悠、山口明人、西毅
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Year and Date
  2010-11-29
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] The analysis of sphingosine 1-phosphate secretion from cells expressing Spns22010
- Author(s)
  Hisano, Y., Yamaguchi, A., Nish, T.
- Organizer
  51st International conference on the Bioscience of Lipids
- Place of Presentation
  Alhondiga Conference Center, Bilbao, Spain
- Year and Date
  2010-09-07
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Structural basis of multidrug recognition2010
- Author(s)
  Akihito Yamaguchi
- Organizer
  Nanofair 2010 8th International Nanotechnology Symposium
- Place of Presentation
  International Congress Center Dresden, Germany(招待講演)
- Year and Date
  2010-07-06
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] スフィンゴシン1リン酸輸送体の同定と生理機能の解析2010
- Author(s)
  西毅、久野悠、山口明人
- Organizer
  第52回日本脂質生化学会
- Place of Presentation
  伊香保・森秋旅館
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Effects of pyridopyrimidine(PP)and Phe-Arg-β-naphthylamide(PAN)on MexB & MexY in Escherichia coli2010
- Author(s)
  Matsumoto Y., Hayama K., Iino R., Nishino K., Noji H., Yamaguchi A.
- Organizer
  第83回日本細菌学会総会
- Place of Presentation
  神奈川
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] RNA chaperone regulates the multidrug transporter AcrB in Escherichia coli2010
- Author(s)
  S.Yamasaki, J.Yamada, H.Hirakawa, M.Hayashi-Nishino, A.Yamaguchi, K.Nishino
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Impact of Hfq on multidrug resistance in Escherichia coli2010
- Author(s)
  S.Yamasaki, J.Yamada, H.Hirakawa, M.Hayashi-Nishino, A.Yamaguchi, K.Nishino
- Organizer
  The 10th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji, Hyogo
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] S1P輸送体SPNS2の生理機能の解析2010
- Author(s)
  西毅、久野悠、山口明人
- Organizer
  第36回日本生体エネルギー研究会
- Place of Presentation
  大阪大学銀杏会館
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Functional analysis of a novel S1P transporter, SPNS22010
- Author(s)
  Y.Hisano, A.Yamaguchi, T.Nishi
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrABの発現制御機構解析2010
- Author(s)
  二階堂英司、城阪郁江、中島良介、櫻井啓介、山口明人、西野邦彦
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrABの発現制御ネットワーク解析2010
- Author(s)
  二階堂英司、城阪郁江、中島良介、山口明人、西野邦彦
- Organizer
  第83回日本細菌学会総会
- Place of Presentation
  神奈川
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Role of the RNA chaperon Hfq in multidrug resistance of Escherichia coli2010
- Author(s)
  Nishino, K., S.Yamasaki, M.Hayashi-Nishino, A.Yamaguchi
- Organizer
  Joint meeting of the NZ Microbiological Society and NZ Society for Biochemistry & Molecular Biology
- Place of Presentation
  The Univ.Auckland, New Zealand
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] S1P輸送体Spns2のヒトオルソログの機能解析2010
- Author(s)
  久野悠、川原敦雄、山口明人、西毅
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrAB発現制御因子RamRのX線結晶構造解析2010
- Author(s)
  二階堂英司、櫻井啓介、西野邦彦、山口明人、中島良介
- Organizer
  第48回日本生物物理学会
- Place of Presentation
  東北大、宮城
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 排出ポンプ阻害剤Phe-Arg-ss-naphtylamide (PAN)の外膜障害作用2010
- Author(s)
  松本佳巳、葉山浩平、飯野亮太、西野邦彦、野地博行、山口明人
- Organizer
  第39回薬剤耐性菌研究会
- Place of Presentation
  伊香保、群馬
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 大腸菌マクロライド排出蛋白質の膜局在2010
- Author(s)
  平田隆弘、北村昭夫、西野邦彦、山口明人
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium2010
- Author(s)
  T.Horiyama, A.Yamaguchi, K.Nishino
- Organizer
  The 10th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji, Hyogo
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium2010
- Author(s)
  T.Horiyama, A.Yamaguchi, K.Nishino
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Characterization of the sphingoshin-1-phosphate transporter2009
- Author(s)
  Nishi N., Kobayashi N., Hisano Y., Yamaguchi A.
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-11-30
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Effects of lipoprotein overproduction on the induction of xenobiotic transporters involved in multidrug resistance in Salmonella enterica2009
- Author(s)
  Shirosaka I., Nikaido E., Yamaguchi A., Nishino K.
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 血小板様分子を産生するMEG-01細胞を用いたS1P輸送体の探索2009
- Author(s)
  久野悠、西毅、山口明人
- Organizer
  第4回トランスポーター研究会
- Place of Presentation
  東京
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Salmonella gene regulation mechanism by RamA in response to signals(ポスター)2009
- Author(s)
  Nikaido E., Shirosaka I, Nakashima R., Yamaguchi A., Nishino K.
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Membrane-damaging activity of Phe-Arg-β-Naphthylamide in Escherichiacol2009
- Author(s)
  Matsumoto Y., Hayama K., Iino R., Nishino K., Noji H., Yamaguchi A.
- Organizer
  49years ICAAC, Interscience Conference on Antimicrobial Agents and Chemotherapy
- Place of Presentation
  San Francisco, USA
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 外部シグナルによるサルモネラ異物排出トランスポーターAcrAB発現制御メカニズム解析2009
- Author(s)
  二階堂英司、城阪郁江、中島良介、山口明人、西野邦彦
- Organizer
  第3回細菌学・若手コロッセウム
- Place of Presentation
  宮崎
- Year and Date
  2009-10-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Regulation mechanism of Salmonella AcrAB Multidrug Efflux Pump in Response to Extracellular Signals2009
- Author(s)
  Nikaido E., Shirosaka I., Nakashima R., Yamaguchi A., Nishino K.
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-11-30
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrAB誘導に関与するRamAおよびRamRの解析2009
- Author(s)
  城阪郁江、二階堂英司、中島良介、山口明人
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Autophagy and the Endoplasmic Reticulum2009
- Author(s)
  Hayashi-Nishino M., Fujita N., Noda T., Yamaguchi A., Yoshimori T., Yamamoto A.
- Organizer
  5th International Symposium on Autophagy
- Place of Presentation
  滋賀
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Electron tomography revealed a subdomain of the endoplasmic reticulum as a cradle for autophagosome formation2009
- Author(s)
  Hayashi-Nishino M., Fujita N., Noda T., Yamaguchi A., Nishino K., Yoshimori T., Yamamoto A.
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Roles of bacterial xenobiotic transporters in immune evasion2009
- Author(s)
  Ueda T., Hayashi-Nishino M., Yamaguchi A., Nishino K.
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 排出ポンプ阻害活性と膜障害作用の分離評価2009
- Author(s)
  松本佳巳、西野邦彦、飯野亮太、野地博行、山口明人
- Organizer
  第57回日本化学療法学会総会
- Place of Presentation
  東京
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 新規S1P輸送体Spns2の機能解析2009
- Author(s)
  久野悠、川原敦雄、山口明人、西毅
- Organizer
  日本生体エネルギー研究会第35回討論会
- Place of Presentation
  北海道
- Year and Date
  2009-12-19
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] ラット赤血球におけるATP依存的スフィンゴシン1リン酸輸送体の解析2009
- Author(s)
  小林直木、小林伸好、西毅、山口明人
- Organizer
  第4回トランスポーター研究会
- Place of Presentation
  東京
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Functional analysis of human spinster-like protein 3 ; a homologue of sphingosine 1-phosphate transporter, spns22009
- Author(s)
  Murata M., Hisano Y., Yamaguchi A., Nishi T.
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Roles of xenobiotic transporters in bacterial drug resistance and virulence2009
- Author(s)
  Nishino K., Yamaguchi A.
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 大腸菌RND型薬剤排出ポンプの進化2009
- Author(s)
  田中真奈美、川下理日人、高木達也、安永照雄、山口明人、西野邦彦
- Organizer
  第11回日本進化学会大会
- Place of Presentation
  北海道
- Year and Date
  2009-09-03
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] スフィンゴシン1-リン酸(S1P)輸送体Spns2による心臓発生の制御機構2009
- Author(s)
  久野悠、川原敦雄、山口明人、西毅、望月直樹
- Organizer
  第19回日本循環薬理学会
- Place of Presentation
  京都
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Sphingosine-1-phosphate (S1P) Release From Erythrocytes Mediated By ATP-dependent Transporter2009
- Author(s)
  N. Kobayashi, N. Kobayashi, T. Nishi, A. Yamaguchi
- Organizer
  12th Sanken International Symposium/7th nanote chnology center international symposium/2nd MSTEC international symposium/1st Sanken Alliance Symposium
- Place of Presentation
  Osaka
- Year and Date
  2009-01-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] スフィンゴシン1-リン酸(S1P)の光反応性アナログを用いたS1P輸送体の探索2009
- Author(s)
  小林直木、西毅、山口明人
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Spns2はスフィンゴシン-1-リン酸(S1P)の細胞外への放出を制御する2009
- Author(s)
  川原敦雄、西毅、久野悠、山口明人、望月直樹
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Identification of the transporter that export sphingosine 1-phosphate from the cells2009
- Author(s)
  Yamaguchi A.
- Organizer
  11th International Conference-Cancun
- Place of Presentation
  Mexico
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Sphingosine 1-phosphate Exporter Spins2 Identification of the transporter that export sphingosine 1-phosphate from the cells2009
- Author(s)
  Yamaguchi A.
- Organizer
  11th International Conference
- Place of Presentation
  Cancun, Mexico
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Electron Tomography Revealed a Subdomain of the Endoplasmic Reticulum as a Cradle for Autophagosome Formation2009
- Author(s)
  Hayashi-Nishlino M., Fujita N., Noda T., Yamaguchi A., Yoshimori T., Yamamoto A.
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  愛知
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] The localization study of a bacterial efflux transporter2009
- Author(s)
  Hirata T., Kitamura A., Nishino K., Yamaguchi A.
- Organizer
  第31回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-11-30
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Fluorescein di-β-D-galactopyranoside(FDG)を用いた排出ポンプ阻害剤の評価2009
- Author(s)
  松本佳巳、葉山浩平、飯野亮太、西野邦彦、野地博行、山口明人
- Organizer
  第38回薬剤耐性菌研究会
- Place of Presentation
  群馬
- Year and Date
  2009-11-19
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Roles of xenobiotic transporters in bacterial drug resistance and virulence2009
- Author(s)
  Nishino, K., Yamaguchi A.
- Organizer
  The Awaji International Forum on Infection and Immunity
- Place of Presentation
  兵庫
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 血小板モデル細胞を用いたS1P輸送体の探索2009
- Author(s)
  久野悠、山口明人、西毅
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Salmonella gene regulation mechanism by RamA in response to signals(口頭)2009
- Author(s)
  Nikaido E., Shirosaka I, Nakashima R., Yamaguchi A., Nishino K.
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ多剤排出トランスポーターの生理機能解明2009
- Author(s)
  西野邦彦、二階堂英司、松本佳巳、山口明人
- Organizer
  第57回日本化学療法学会西日本支部総会
- Place of Presentation
  愛知
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Roles of multidrug efflux pumps in antimicrobial peptide resistance of Salmonella enterica2008
- Author(s)
  ○Tomoyuki Nakano, Kunihiko Nishino and Akihito Yamaguchi
- Organizer
  Florence Conference on Phenotype MicroArray Analysis of Microorganisms
- Place of Presentation
  Florence, Italy
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 異物排出トランスポーターの構造・機能とその制御に関する研究2008
- Author(s)
  山口明人
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  パシフィコ横浜(横浜)(日本薬学会賞受賞公演、招待講演)
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Regulatory Network of Multidrug Transporters Reveals their Physiological Role in Salmonella Virulence2008
- Author(s)
  K. Nishino, A. Yamaguchi
- Organizer
  American Society for Microbiology 108th General Meeting
- Place of Presentation
  Boston, Massachusetts
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Regulatory network of multidrug transporters reveals their physiological role in Salmonella virulence2008
- Author(s)
  西野邦彦, 山口明人
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 大腸菌薬剤排出タンパク質の細胞内局在2008
- Author(s)
  ○平田隆弘、北村昭夫、西野邦彦、山口明人
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 脂溶性情報伝達物質の細胞外放出機構の解明2008
- Author(s)
  西毅, 小林直木, 山口明人
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Regulatory network of AcrAB multidrug efflux pump in Salmonella and its role in response to metabolites2008
- Author(s)
  ○Eiji Nikaido, Kunihiko Nishino and Akihito Yamaguchi
- Organizer
  Florence Conference on Phenotype MicroArray Analysis of Microorganisms
- Place of Presentation
  Florence, Italy
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Characterization of ATP-dependent transport of the sphingosine-1-phosphate (S1P) in rat erythrocytes2008
- Author(s)
  ○小林直木、小林信好、西毅、山口明人
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrABの発現制御と環境応答におけるRamAの役割2008
- Author(s)
  二階堂英司, 西野邦彦, 山口明人
- Organizer
  第2回細菌学・若手コロッセウム
- Place of Presentation
  神奈川
- Year and Date
  2008-08-03
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 輸送体を介した赤血球からのスフィンゴシン1リン酸放出機構2008
- Author(s)
  小林直木, 小林伸好, 西毅, 山口明人
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 細菌異物排出タンパクの構造・機能とその発現制御に関する研究2008
- Author(s)
  ○山口明人
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Regulatory network of multidrug efflux pumps reveals their physiological role in Salmonella virulence2008
- Author(s)
  K. Nishino, A. Yamaguchi
- Organizer
  Gordon Research Conference
- Place of Presentation
  MA, USA
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrAB生理的役割と発現誘導機構の解析2008
- Author(s)
  ○二階堂英司、西野邦彦、山口明人
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ菌薬剤排出ポンプの生理機能 -多剤耐性および病原性発現における役割について-2008
- Author(s)
  ○西野邦彦、山口明人
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターEmrABの機能解析2008
- Author(s)
  ○坂田博樹、西野邦彦、山口明人
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Studies on the Structure, Function and Regulation of Xenobiotic Exporters2008
- Author(s)
  ○山口明人
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 電子線トモグラフィーを用いたダイナミン1KOシナプスにおけるエンドサイトーシス中間体の解析2008
- Author(s)
  西野-林美都子, Eileen O'Toole, Shawn Ferguson, 西野邦彦, 山口明人, Pietro De Camilli
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターEmrABの機能解析2008
- Author(s)
  ○坂田博樹、西野邦彦、山口明人
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 細菌異物排出タンパクの構造・機能とその発現制御に関する研究2008
- Author(s)
  山口明人
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  国立京都国際会館(京都)(浅川賞受賞講演、招待講演)
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Analysis of the S1P transporter in MEG-01 cell line2008
- Author(s)
  ○久野悠、西毅、山口明人
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Metal Resistance Roles of Multidrug Transporters in Salmonella enterica2008
- Author(s)
  ○西野邦彦、二階堂英司、山口明人
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Cellular localization of drug efflux transporters in Escherichia coli2008
- Author(s)
  ○平田隆弘、北村昭夫、西野邦彦、山口明人
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 細菌トランスポートソームのレジストーム解析2008
- Author(s)
  西野邦彦, 二階堂英司, 坂田博樹, 中濃知志, 田中真奈美, 西野-林美都子, 上田珠美, 城阪郁江, 山口明人
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Molecular Design of the Carbenicillin Hyper-Resistance AcrB Multidrug Exporter in Escherichia coli2008
- Author(s)
  A. Iwata, N. Kobayashi, S. Murakami, A. Yamaguchi
- Organizer
  22nd Annual Symposium of The Protein Siciety
- Place of Presentation
  San Diego, California USA
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Physiological functions of bacterial multidrug efflux pumps2008
- Author(s)
  ○Kunihiko Nishino and Akihito Yamaguchi
- Organizer
  The 3rd CNU-SANKEN Joint Symposium on Advanced Materials Science
- Place of Presentation
  Chungnam National University, Korea
- Year and Date
  2008-02-27
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 神経細胞におけるABC (ATP Binding Cassette)輸送体ABCA5の発現2008
- Author(s)
  大東穂, 西毅, 山口明人
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Regulation of the AcrAB Multidrug Efflux Pump in Salmonella enterica by RamA in Response to Environmental Signals2008
- Author(s)
  E. Nikaido, K. Nishino, A. Yamaguchi
- Organizer
  American Society for Microbiology 108th General Meeting
- Place of Presentation
  Boston, Massachusetts
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 多剤排出トランスポーターの構造と機能発現2008
- Author(s)
  ○山口明人
- Organizer
  第2回分子生物薬剤学セミナー「トランスポーター科学最前線」
- Place of Presentation
  金沢大学、石川県
- Year and Date
  2008-02-16
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Electron Tomography Revealed the Endoplasmic Reticulum as a Cradle for Autophagosome Formation2008
- Author(s)
  M. Hayashi-Nishino, N. Fujita, T. Noda, A. Yamaguchi, T. Yoshimori, A. Yamamoto
- Organizer
  The American Society for Cell Biology 48th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Analysis of the expression site and the physiological role of mouse ABC A52008
- Author(s)
  ○大東穂、西毅、山口明人
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 大腸菌異物排出タンパク質AcrBの基質認識における芳香族アミノ酸の重要性2008
- Author(s)
  岩田歩, 村上聡, 山口明人
- Organizer
  第46回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] サルモネラ異物排出トランスポーターAcrAB制御因子の同定2008
- Author(s)
  ○二階堂英司、西野邦彦、山口明人
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Structure and Mechanism of the Tripartite Multidrug Exporter2008
- Author(s)
  Yamaguchi A.
- Organizer
  The Joint 4th AOHUPO(Asian Oceania Human Proteome Organisation) and 2nd PRICPS(Pacific Rim International Conference on Protein Science)
- Place of Presentation
  Carins Convention Center, Australia
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 膜傷害保護における異物排出トランスポーターの役割2008
- Author(s)
  坂田博樹, 西野邦彦, 上田珠美, 山口明人
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 膜傷害保護における異物排出トランスポーターの役割2008
- Author(s)
  坂田博樹, 西野邦彦, 山口明人
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 異物排出蛋白質発現抑制因子AcrSの機能解明とAcrAB,AcrEFの発現制御2008
- Author(s)
  ○平川秀忠、西野邦彦、平田隆弘、山口明人
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 抗菌ペプチド耐性における多剤排出ポンプの役割2008
- Author(s)
  中濃知志, 西野邦彦, 山口明人
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] MC-7-05 MEG-01細胞からのS1P放出輸送体のsiRNAによる検索2008
- Author(s)
  久野悠, 西毅, 山口明人
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] RamAによるサルモネラ異物排出トランスポーターAcrAB発現制御機構の解析2008
- Author(s)
  二階堂英司, 西野邦彦, 城阪郁江, 山口明人
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] AcrAB multidrug efflux pump regulation in Salmonella enterica serovar Typhimurium by RamA in response to environmental signals2008
- Author(s)
  K. Nishino, E. Nikaido, A. Yamaguchi
- Organizer
  The Awaji International Forum on Infection and Immunity
- Place of Presentation
  兵庫
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Structure and Mechanism of the Tripartite Multidrug Exporter2008
- Author(s)
  A. Yamaguchi, S. Murakami
- Organizer
  The Joint 4^<th> AOHUPO (Asian Oceania Human Proteome Organization) and 2^<nd> PRICPS (Pacific Rim International Conference on Protein Science)
- Place of Presentation
  Cairns, Australia
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Electron tomographic reconstruction of clathrin coated endocytic intermediates in nerve terminals that lack dynamin 12008
- Author(s)
  M. Hayashi-Nishino, E. O'Toole, S. Ferguson, A. Yamaguchi, P. De Camilli
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Structural Basis of Bacterial Multidrug Export2008
- Author(s)
  ○Akihito Yamaguchi
- Organizer
  11th Sanken International Symposium/6th nanotechnology center international symposium/1st MSTEC international symposium
- Place of Presentation
  Hyogo
- Year and Date
  2008-02-05
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Cellular localization of mouse ABCA5 proteins in various mouse tissues2007
- Author(s)
  ○大東穂、西毅、山口明人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Regulation mechanisms of the acrAB multidrug efflux pump in Salmonella enterica in response to bacterial metabolites2007
- Author(s)
  ○Eiji Nikaido, Kunihiko Nishino and Akihito Yamaguchi
- Organizer
  7th The Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji Yumebutai International Conference Center
- Year and Date
  2007-09-03
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Metabolites of Escherichia coli Induce the Expression of Multidrug Efflux pumps in Salmonella enterica2007
- Author(s)
  ○Eiji Nikaido, Kunihiko Nishino and Akihito Yamaguchi
- Organizer
  American Society of Microbiology, 107th General Meeting
- Place of Presentation
  Metro Toronto Convention Center, Toronto, Canada
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] マウスABCA5の生理機能の解明2007
- Author(s)
  ○大東穂、西毅、山口明人
- Organizer
  日本生体エネルギー研究会第33回討論会
- Place of Presentation
  山口
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Regulatory network of multidrug transporters reveals their physiological role in Salmonella virulence2007
- Author(s)
  ○Kunihiko Nishino, Eiji Nikaido, Hiroki Sakata, Tomoyuki Nakano, Manami Tanaka and Akihito Yamaguchi
- Organizer
  7th The Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji Yumebutai International Conference Center
- Year and Date
  2007-09-01
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 細菌代謝物によるサルモネラ菌異物排出トランスポーターAcrAB発現誘導機構の解析2007
- Author(s)
  ○二階堂英司、西野邦彦、坂田博樹、中濃知志、田中真奈美、山口明人
- Organizer
  第19回微生物シンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Analysis of the xenobiotic exporter EmrAB in Salmonella enterica serovar Typhimurium2007
- Author(s)
  ○坂田博樹、西野邦彦、山口明人
- Organizer
  第19回微生物シンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Identification of the sphingosine-1-phosphate export system in rat erythrocytes2007
- Author(s)
  ○小林直木、小林伸好、西毅、山口明人
- Organizer
  第29回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-11-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Roles of indole signaling and intercellular signal transduction on type III secretion system-dependent pathogenicity in EHEC2007
- Author(s)
  ○Hidetada Hirakawa, Toshio Kodama, Takeshi Honda and Akihito Yamaguchi
- Organizer
  3rd ASM Conference on Cell-Cell Communication in Bacteria
- Place of Presentation
  Texas, USA
- Year and Date
  2007-10-07
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Identification of novel gene products which play roles on biofilm formation in Escherichia coli2007
- Author(s)
  ○王麗媛、平田隆弘、平川秀忠、西野邦彦、山口明人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Identification of novel gene products which play roles on biofilm formation in Escherichia coli2007
- Author(s)
  ○王麗媛、平田隆弘、平川秀忠、西野邦彦、山口明人
- Organizer
  第19回微生物シンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Analysis of the xenobiotic exporter EmrAB in Salmonella enterica serovar Typhimurium2007
- Author(s)
  ○坂田博樹、西野邦彦、山口明人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 大腸菌異物排出蛋白質MacABの極への局在2007
- Author(s)
  ○平田隆弘、北村昭夫、西野邦彦、山口明人
- Organizer
  第4回21世紀大腸菌研究会
- Place of Presentation
  静岡
- Year and Date
  2007-07-18
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Characterization of ATP-dependent sphingosine-1-phosphate transport in rat erythrocytes by using the inside-out membrane vesicles2007
- Author(s)
  ○小林直木、小林伸好、西毅、山口明人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] The regulatory mechanism of the AcrAB and AcrEF multidrug exporter system by AcrS in Escherichia coli2007
- Author(s)
  ○平川秀忠、Ulrike Theisen、小林あすか、平田隆弘、西野邦彦、山口明人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Visualization of Escherichia coli AcrAB-TolC efflux pump activity using ultra small chambers2007
- Author(s)
  ○Yoshimi Matsumoto, Kunihiko Nishino, Ryota Iino, Syoichi Sakakihara, Masayoshi Nakata, Hiroyuk Nojii and Akihito Yamaguchi
- Organizer
  47th Interscience Conference on Antimicrobial Agents and Chemotherapy
- Place of Presentation
  McCormick Place, Illinois USA
- Year and Date
  2007-09-18
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] フェムトリッター(fL)チャンバーを用いた薬剤排出ポンプ阻害薬の評価法2007
- Author(s)
  ○松本佳巳、西野邦彦、飯野亮太、榊原昇一、仲田昌義、二階堂英司、山口明人、野地博行、竹内昌治
- Organizer
  第55回日本化学療法学会総会
- Place of Presentation
  仙台
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Novel Aspects of Mechanisms of Antibacterial Resistance Revealed by Crystal Structure2007
- Author(s)
  Yamaguchi A.
- Organizer
  47th Interscience Conference on Antimicrobial Agents and Chemotherapy
- Place of Presentation
  McCormick Place, Illinois USA
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] フェムトリッターチャンバーを用いた薬剤排出ポンプの研究2007
- Author(s)
  ○松本佳巳、西野邦彦、飯野亮太、榊原秀一、仲田昌義、野地博行、山口明人
- Organizer
  第19回微生物シンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2007-09-08
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Single Cell Measurement of Bacterial Drug Efflux in Femtoliter Chamber Array2007
- Author(s)
  ○Kunihiko Nishino, Ryota Iino, Masaaki Nakata, Yoshimi Matsumoto, Eiji Nikaido, Syoichi Sakakihara, Syoji Takeuchi, Akihito Yamaguchi and Hiroyuki Noji
- Organizer
  American Society of Microbiology, 107th General Meeting
- Place of Presentation
  Metro Toronto Convention Center, Toronto, Canada
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Identification of the function of ABCA7 in mouse platelets2007
- Author(s)
  ○尾上麻実子、柴田紗貴子、西毅、山口明人
- Organizer
  第29回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-11-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] ライフサイエンスの新展開2007
- Author(s)
  ○山口明人
- Organizer
  平成19年度産研テクノサロン(第3回例会)
- Place of Presentation
  大阪大学接合科学研究所
- Year and Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Novel Aspects of Mechanisms of Antibacterial Resistance Revealed by Crystal Structure2007
- Author(s)
  Yamaguchi A.
- Organizer
  47th Interscience Conference on Antimicrobial Agents and Chemotherapy
- Place of Presentation
  McCormick Place(Chicago, Illinois, USA)(招待講演)
- Year and Date
  2007-09-18
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 細菌代謝物によるサルモネラ菌異物排出トランスポーターAcrAB-TolCシステム発現制御機構の解析2007
- Author(s)
  ○二階堂英司、西野邦彦、山口明人
- Organizer
  第29回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-11-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Functional roles of ABCA7 in mouse platelet2007
- Author(s)
  ○尾上麻実子、柴田紗貴子、西毅、山口明人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Expression and cellular localization of ABCA6 in mouse liver2007
- Author(s)
  ○宮田耕資、大東穂、西毅、山口明人
- Organizer
  第29回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-11-26
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Release of sphingosine 1-phosphate from platelet-like particles derived from MEG-01 cells MEG-012007
- Author(s)
  ○久野悠、西毅、山口明人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Induction mechanism of AcrAB in Salmonella enterica2007
- Author(s)
  ○二階堂英司、西野邦彦、山口明人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] 細菌オーファン輸送体の生理機能解明2007
- Author(s)
  ○西野邦彦、山口明人
- Organizer
  第55回日本化学療法学会総会
- Place of Presentation
  仙台
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] ATP依存的な輸送体を介した脂質メディエーター放出機構2007
- Author(s)
  ○西毅、小林直木、山口明人
- Organizer
  日本生体エネルギー研究会第33回討論会
- Place of Presentation
  山口
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19109002
[Presentation] Tissue and subcellular localization of mouse ABCA6 transporter2007
- Author(s)
  ○宮田耕資、大東穂、西毅、山口明人
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19109002

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YAMAGUCHI Akihito 山口 明人

YAMAGUCHI AKIHITO 山口 明人

Research Projects

Research Products

Co-Researchers

Structures, functions, regulations and physiological roles of xenobiotic exportersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the crystal structure of antiporters for organic compounds and the mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

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Post-Genomic Approach to Bacterial Xenobiotic Exporter Gene Resources and Investigation of Novel Drug Resistance Mechanisms of BacteriaPrincipal Investigator

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テトラサイクリン排出蛋白の結晶構造解析Principal Investigator

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Molecular Basis and Physiological Roles of Xenobiotic ExportersPrincipal Investigator

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部位特異的化学修飾による膜蛋白質高次構造の決定Principal Investigator

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テトラサイクリン/H^+アンチポーターのプロトン輸送機構とイオンチャンネル機能Principal Investigator

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膜輸送蛋白高次構造の解明Principal Investigator

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Studies on the Bacterial Xenobiotic Efflux MechanismPrincipal Investigator

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イオン駆動型トランスポーターとチャネルの構造・機能協関

Principal Investigator

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テトラサイクリン/H^+アンチポーターのプロトン輸送機構とイオンチャンネル機能Principal Investigator

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Development of the Screening System for Inhibitors of Bacterial Drug ExportersPrincipal Investigator

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Involvement of bacterial membranes in drug resistance

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Studies on the Molecular Structure and Function of Tetracycline Efflux ProteinPrincipal Investigator

YAMAGUCHI Akihito 山口明人

YAMAGUCHI AKIHITO 山口明人

[Book] タンパク質科学構造・物性・機能2005

[Book] タンパク質科学構造・物性・機能(編集者:後藤祐児、桑島邦博、谷澤克行)2005

[Book] タンパク質科学構造・物性・機能2005

[Book] タンパク質科学構造・物性・機能(編集者 : 後藤祐児、桑島邦博、谷澤克行)2005