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WATANABE Kazuo  渡辺 和夫

ORCIDConnect your ORCID iD *help
Researcher Number 80019124
External Links
Affiliation (based on the past Project Information) *help 2000: Chiba University Faculty of Pharmaceutical Sciences Professor, 薬学部, 名誉教授
1988 – 1999: 千葉大学, 薬学部, 教授
Review Section/Research Field
Principal Investigator
Biological pharmacy
Except Principal Investigator
Chemical pharmacy / 医薬分子機能学 / Biological pharmacy
Keywords
Principal Investigator
グルタミン酸受容体 / 脳機能改善薬 / GABA / gastric ulcer / カプサイシン / 胃酸分泌 / 中枢神経 / 胃潰瘍 / 胃液分泌 / Receptor … More / Glutamic Acid / Opiodes / Drugs for Brain Insufficiency / Gamma-amino-butyric acid / Appetite / Gastric Acid Secretion / Central Nervous System / レセプター / オビオイドペプチド / ペントバルビタール / レセプタ- / グルタミン酸 / オピオイド / γ-アミノ酪酸 / 食欲 / Nootropic Drug / Opioid receptor / Glutamate receptor / GABA receptor / Neurotropic Crude Drug Components / Neurotropic Fungal Metabolites / 1-Substituted Tetrahydro-beta-carbolines / Asymmetric Pictet-Spengler Reaction / 抗痴呆薬 / 向精神性伝承薬 / GABA作動性神経 / グルタミン酸作動性神経 / 八方向放射状迷路 / 痙攣性菌類代謝産物 / ニューロステロイド / mitragynine / NO / 向神経性伝承薬 / 不斉Pictet-spengler反応 / β-カルボリン系菌類代謝産物 / インドールアルカロイド / MAO阻害活性成分 / 身体依存性 / 鎮痛作用 / 酢酸ライジング抑制活性成分 / 不斉Picter-Spengler反応 / 1-置換-テトラヒドロ-β-カルボリン / オピオイド受容体 / GABA受容体 / 向神経性生薬成分 / 向神経性菌類代謝産物 / 不斉Pictet-Spengler反応 / enterocromaffin like cell / glutamate receptor / oxygen radical / gastric mucosal defense system / Helicobacter pylori / antiulcer drugs / gastric antral ulcer / 2-デオキシ-D-グルコース / ヘリコバクター ピロリ / 胃粘膜血流 / 胃粘膜保護作用 / 胃幽門洞 / 幽門洞 / 実験潰瘍 / エンテロクロマフィン様細胞 / 活性酸素 / 胃粘膜防御系 / ヘリコバクター・ピロリ / 潰瘍治療薬 / 幽門洞潰瘍 / hypothalamus / central nervous system / receptor / excitatory amino acids / gastric motility / gastric acid secretion / gastric function / プロゲステロン / 視床下部 / 胃運動 / 胃機能 / マイクロダイアリシス / 塩素イオン / 重炭酸イオン / 受容体 / コレシストキニン / 興奮性アミノ酸 … More
Except Principal Investigator
Pueraria mirifica / オピオイド受容体 / Mitragynine / インドールアルカロイド / Mitragyna speciosa / Structure-activity relationship / Opioid receptor / Analgesic activity / Opioid agonist / Indole alkaloid / Mitragyna plant / 構造活性相関 / 鎮痛 / オピオイド作用薬 / ミトラガイニン / ミトラガイナ属 / Solid dispersion / Pharmaceutical technology / Evaluation of biological activity / Estrogenic activity / Natural Product Chemistry / Tropical Medicinal Resources / Thailand / 環境化学 / 分析化学 / 薬理学 / 固体分散 / 製剤工学 / 生物活性評価 / エストロゲン様作用 / Pueraria myrifica / 天然物化学 / 熱帯薬用資源 / タイ / Ca channel / opioid receptor / serotonin receptor / analgesic effect / mitragynine / indole alkaloid / Thai medicinal plant / アルカロイドの化学合成 / Rauwolfia sumatorana / Hunteria zeylanica / オピオイド作用 / アルカロイド化学合成 / 平滑筋収縮作用 / Caチャンネル / セロトニン受容体 / 鎮痛活性 / タイ薬用植物 / Alkaloid / Pharmaceuticals / Antimicrobial activity / Biological active substance / Pharmacological effect / Compounds of medical plants / Development of medicines / Tropical and medical plants / 生物活性物質の探索 / 薬用植物成分の化学構造 / 有効成分の分離方法 / 医薬品開発の基礎研究 / アルカロイド / 医薬品製剤 / 抗微生物活性 / 生理活性物質 / 薬理作用 / 薬用植物成分 / 医薬品開発 / 熱帯薬用植物 / Fungi / Gastric Acid Secretion / Monoamine Oxidase Inhibitors / Central Nervous System / Manzamine C / Eudistomins / beta-Carbolines / Cerebral Insufficiency Improving Activity / 胃液分泌の中枢性調節 / グルタミン酸受容体 / β-カルボリン / 胃液分泌中枢性調節 / 子嚢菌 / モノアミン酸化酵素 / 向中枢神経作用物質 / ユ-ディストミン / スフィンゴ脂質 / βーカルボリン / 脳機能改善薬 / pharmacy education / drug safety / mechanism of drug action / evaluation / pharmaceutical / synthetic drug / natural resources / new drug development / 安全性 / 体内動態 / 薬理学的研究 / 天然薬用資源 / 薬学教育 / 薬物の安全性 / 薬効発現機構 / 薬効評価 / 合成医薬品 / 天然資源 / 新薬開発 / 民族伝統薬物 / 漢方薬 Less
  • Research Projects

    (11 results)
  • Co-Researchers

    (102 People)
  •  Studies on the development of new opioid agonist by utilizing Mitragyna alkaloids as the lead-compounds

    • Principal Investigator
      TAKAYAMA Hiromitsu
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      医薬分子機能学
    • Research Institution
      Chiba University
  •  Utilization and Evaluation of Tropical Medicinal Resources

    • Principal Investigator
      AIMI Norio
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Chemical pharmacy
    • Research Institution
      Chiba University
  •  Studies on the beta-Carboline Derivatives as Lead Compounds of Therapeutics for Brain-Gut and Central Nervous DiseasesPrincipal Investigator

    • Principal Investigator
      WATANABE Kazuo
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  •  Studies on the pharmacological properties of a novel animal model for gastric antral ulcer and on its application to drug evaluation for antiulcer drugsPrincipal Investigator

    • Principal Investigator
      WATANABE Kazuo
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  •  Medicinal Chemistry on Indole Alkaloids from Thai Medicinal Plants

    • Principal Investigator
      SAKAI Shin-ichiro
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  漢方薬を中心とした民族伝統薬物の先端技術による医薬学的解明と科学的確立

    • Principal Investigator
      菊池 徹
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  Basic study on development of medicines from tropical plants

    • Principal Investigator
      HIROSE Seiyu
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Pharmacological Studies on the Role of Excitatory Amino Acids Receptors in the Hypothalamus in the Control of Gastric Functions.Principal Investigator

    • Principal Investigator
      WATANABE Kazuo
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University,Faculty of Pharmaceutical Sciences
  •  General Studies on the Development of Novel Materials and their Evaluation as new Drugs

    • Principal Investigator
      SUZUKI Tokuji
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Survey Investigation of Lead Compounds Towards Cerebral Insufficiency Improving Activity

    • Principal Investigator
      HINO Tohru
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Chiba University
  •  Pharmacological studies on central nervous control systems in gastric acid secretion and on their signal tranduction systems.Principal Investigator

    • Principal Investigator
      WATANABE Kazuo
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  • 1.  YANO Shingo (90009655)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  YAMAZAKI Mikio (70089598)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  HORIE Syunji (50209285)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  HINO Toru (10009160)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  NAKAGAWA Masao (40009171)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  SAKAI Shin-ichiro (20009161)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  AIMI Norio (30009170)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  JAMARI F.
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  KNAUS
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  FRIESEN
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  NOUJAIM
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  LOCOCK
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  TAM
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  PASUTTO
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  BIGGS
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  MICETICH
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  WIEBE
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  WOLOWYK
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  SAWAI Testuo (70009174)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  SATO Testuo (60092061)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  HIROSE Seiyu (40009163)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  WATANABE Hiroshi (10012642)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  ISHII Hisashi (70009166)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  MURAKOSHI Isamu (30009162)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  YAMAMOTO Keiji (50110341)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  TAKAYAMA Hiromitsu (90171561)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 27.  PONGLUX Dhavadee
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 28.  COUTTS
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 29.  MOSKALYK
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 30.  SUZUKI Tokuji (40010219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  UNEMOTO Tsutomu (30089601)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  IMANARI Toshio (20012619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  IGARASHI Kazuei (60089597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  ISHII Itsuko (00202929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  YAMAGUCHI Akihito (60114336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  KITAJIMA Mariko (60195261)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  TSUCHIYA Shizuko (60241973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  SUZUKI Kazuo,t. (90109918)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  ISHIKAWA Tsutomu (20114233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  菊池 徹 (40025680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  野村 靖幸 (00034041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  木村 正康 (60019099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  荻原 幸夫 (70080166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  山根 靖弘 (40009155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  仲井 由宣 (80009159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  細谷 東一郎 (10019648)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  池上 文雄 (90159608)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  ATMIYANAN Preeya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  STOCKIGT Joachim
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  TONGROCH Pavich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  BIGGS D. F.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  KNAUS E. E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  LOCOCK R. A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  PASUTTO F. M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  FRIESEN A. J. D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  COUTTS R. T.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  TAM Y. K.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  NOUJAIM A. A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  WOLOWYK M. W.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  MICETICH R. G.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 61.  MOSKALYK R. E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 62.  WIEBE L. I.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 63.  COUTIS
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 64.  BAVOVADA Rap
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  SAIFAH Ekari
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 66.  KULVANICH Po
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 67.  NIMMANNIT Ub
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 68.  TANTISIRA Ma
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 69.  TONGROACH Pa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 70.  PUMMANGURA S
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 71.  LIPIPAN Vimo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 72.  PRAMYOTHIN P
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 73.  PORNPEN Pramyothin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 74.  RAPEPOL Bavovada
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 75.  UBONTHIP Nimmannit
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 76.  VIMOLMAS Lipipan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 77.  EKARIN Saifah
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 78.  PUMMANGURA Sunibhond
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 79.  TANTISIRA Mayuree H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 80.  PAVICHI Tongroach
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 81.  POJ Kulvanich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 82.  U Nimmannit
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 83.  R Bavovada
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 84.  P Tongroach
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 85.  P Kulvanich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 86.  M Tantisira
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 87.  S Pummangura
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 88.  P Atmiyanan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 89.  D Pouglux
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 90.  SAISORN B.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 91.  POUGLUX D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 92.  TANTISIRA M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 93.  PANG Peter K
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 94.  KTPANG Peter
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 95.  JOACHIM Stoc
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 96.  DHAVADEE Pon
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 97.  PAVICH Tongr
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 98.  JOACHIM Sto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 99.  PETER KT Pa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 100.  DHAVADEE Po
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 101.  PAVICH Tong
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 102.  PETER KT Pan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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