TAKAYAMA Hiromitsu 高山廣光

… Alternative Names

Researcher Number	90171561
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016 – 2020: 千葉大学, 大学院薬学研究院, 教授 2012 – 2016: 千葉大学, 薬学研究科(研究院), 教授 2007 – 2012: Chiba University, Graduate School of Pharmaceutical Sciences, Professor 2005 – 2006: 千葉大学, 大学院薬学研究院, 教授 2004 – 2005: Chiba University, Graduate School of Pharmaceutical Sciences, Professor, 大学院・薬学研究院, 教授 … More
Review Section/Research Field	Principal Investigator Natural medicines / Chemical pharmacy / Science and Engineering / Drug development chemistry / Bioorganic chemistry / Living organism molecular science / 医薬分子機能学 / Pharmaceutical Sciences and related fields Except Principal Investigator Chemical pharmacy / Living organism molecular science / Synthetic chemistry / Applied genomics
Keywords	Principal Investigator アルカロイド / 構造活性相関 / インドールアルカロイド / オピオイド / 全合成 / 脳機能改善薬 / Mitragyna speciosa / リコポジウム / 天然活性物質 / 生物活性物質の探索 … More Except Principal Investigator アルカロイド / Gelsemium elegans / Gelsemium sempervirens / メタボロミクス / フラボノイド / 全合成 / インドールアルカロイド / Rubiaceae / 毛状根 / alkaloid / 抗腫瘍活性 / antitumor activity / indole alkaloid / トランスクリプトミクス / 生合成 / シロイヌナズナ / ゲノム機能科学 / バイオインスパイアード反応 / インド-ルアルカロイド / 構造決定 / Rauwolfia serpentina / Raumaclines / Aspidosperma quebracho blanco / 化学変換 / Indole Alkaloids / アカネ科 / 二次代謝 / Mitragyna speciosa / オピオイド受容体 / Ophiorrhiza pumila / camptothecin / マチン科 / イリドイド / Loganiaceae / アントシアニン / メタボローム / EC_<50> / antioxidant / opioid agonist / prolyl endopeptidase / 脱顆粒抑制作用 / cytotoxic / Malaysian medicinal plant / anti-HSV-1 / 植物成分 / 二次代謝産物 / ゲノム機能学 / 薬用植物 / システイン / 水中反応 / ワンポット反応 / ジケトピペラジン / 転位反応 / プレニル化反応 / 一電子酸化 / 二量化反応 / 植物組織培養 / 生物変換 / Aspidochibine / Raumacline / アジマリン / Aspidasperma queblacho blanco / Aspidosperma gmbir / Plant Tissue Cultures / Structure Elucidation / Rauwolfia serpentina Benth / Biotransformation of ajmaline / Aspidochibine. / ゲルセミウム / 生合成的化学合成 / 生合成模擬反応 / 化学変換反応 / Gelsemium / Biomimetic Synthesis / 植物細胞培養 / 細胞融合 / 再分化 / キョウチクトウ科 / アントラキノン / 融合細胞 / Rhazya stricta / Ophiorrhiza spp. / Plant cell culture / Cell fusion / Differentiation / Apocynaceae / Indole alkaloid / Anthraquinone / Secondary metabolism / タイ薬用植物 / Mitragynine / 鎮痛活性 / セロトニン受容体 / Caチャンネル / 平滑筋収縮作用 / アルカロイド化学合成 / オピオイド作用 / Hunteria zeylanica / Rauwolfia sumatorana / アルカロイドの化学合成 / Thai medicinal plant / mitragynine / analgesic effect / serotonin receptor / opioid receptor / Ca channel / Ophiorrhiza pimila / 再生植物 / Camphothecin / Deoxypumilosid / キラル合成 / Camptothecin / 9-β-D-Glucosyloxycamptothecin / 組織培養 / pumiloside / Deoxypumilosides / regenerated plants / hairy roots / deoxypumiloside / chiral synthesis / ミトラガイナスペシオーサ / インドール / イソキノリン / 海洋天然物 / オピオイド / ミトラガイニン / 化学合成 / Mitragyna spociosa / indole / isoquinoline / marine natural product / structure elucidation / total synthesis / opioid / Gelsemium sempervilens / カルス / DNAによる系統解析 / 毒性 / テルペン / 急性毒性 / アゼチジン環 / 系統解析 / callus / phylogenelic analyses of DNA / toxicity / 代謝 / 多変量解析 / 自己組織化マップ / 栄養ストレス / 機能ゲノミクス / グルコシノレート / DNAマイクロアレイ / metabolomics / transcriptomics / functional genomics / metabolism / Arabidopsis thaliana / カンプトテシン / キノリチジンアルカロイド / 実用植物 / トランスクリプトー / 物質生産 / GST / RNAi / モデル植物 / 生産制御 / メタボロム / トランスクリプトム / anthocyanin / quinolizidine alkaloid / secondary metabolism / comparative genetics / biosynthesis / Gelsedine / 腫瘍細胞殺傷活性 / イロドイド / マナン科 / 細胞毒性 / 2-アシルインドール / gelsedine / cytotoxicity / α,β-不飽和スルホキシド / 不斉ディールス・アルダー反応 / 不斉環化付加 / 高ジアステレオ選択性 / <alpha> , <beta> -Unsaturated Sulfoxides / Asymmetric Diels-Alder Reaction / Asymmetric Cycloaddition / セコロガニン / 不斉有機触媒反応 / 生合成模倣反応 / 集団的合成 / 生合成模擬的全合成 / 集団的全合成 / Pictet-Spegler反応 / ストリクトシジン / ガイソシジン / 生合成模擬的合成 / Pictet-Spengler反応 / キニーネ / 有機分子触媒 / モノテルペノイドインドールアルカロイド / 生物活性アルカロイド / 生合成模擬的反応 Less

Studies on development of novel asymmetric organocatalysts and oligonucleotide-recognition probes based on natural alkaloidPrincipal Investigator
- Principal Investigator
  
  Takayama Hiromitsu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Chiba University
Collective synthesis of monoterpenoid indole alkaloid using bioinspired reactions
- Principal Investigator
  
  Ishikawa Hayato
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Kumamoto University
Studies on search and synthesis of plant alkaloids for the development of new medicines for pain and improving the memory disordersPrincipal Investigator
- Principal Investigator
  
  TAKAYAMA HIROMITSU
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Chiba University
Studies on the synthesis of SPECT probe to elucidate the in vivo dynamics of natural opioidsPrincipal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Natural medicines
- Research Institution
  Chiba University
Synthetic study of biologically active alkaloids using bio-inspired reactions
- Principal Investigator
  
  ISHIKAWA HAYATO
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Kumamoto University
Search for natural molecules that control memory and pain from medicinal resources and drug development reserachPrincipal Investigator
- Principal Investigator
  
  TAKAYAMA HIROMITSU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Chiba University
Studies on isolation, total synthesis and medicinal chemistryof natural products with regulating activities on memory and pain.Principal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Chiba University
新規NMDA受容体チャネルブロッカー探索による脳機能改善薬の創製Principal Investigator
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Chiba University
Phytochemical genomics : Genomic basis for phytochemical diversity
- Principal Investigator
  
  SAITO Kazuki
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Chiba University
Search, asymmetric synthesis, and medicinal chemistry study on the plant alkaloids that regulate the brain nervous system.Principal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Chiba University
オピオイド受容体サブタイプを分子標的とする機能性コリナンテ型アルカロイドの開発Principal Investigator
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Chiba University
モルヒネを超える新規オピオイド性鎮痛アルカロイドの探索と創製Principal Investigator
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Chiba University
Comparative genomics of model plant and non-model plants based on metabolome analysis
- Principal Investigator
  
  YAMAZAKI Mami
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Chiba University
Studies on the Gelsemium Alkaloids for the Discovery and Development of New Antitumor Natural Products.
- Principal Investigator
  
  KITAJIMA Mariko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Chiba University
Metabolomics-based post-genome science in plants
- Principal Investigator
  
  SAITO Kazuki
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Chiba University
益々重要性が認識されつつある天然医薬資源の健康科学への拡大応用に関する調査研究
- Principal Investigator
  
  野原稔弘
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kumamoto University
Development of New Type of Potent Opioid Agonists and the Molecular Mechanism for Exhibiting their Analgesic ActivityPrincipal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Study on the Alkaloid Production of Two Gelsemium Plants by Using their Callus Cultures and Chemical and Pharmacological Investigation of Gelsemium Alkaloids.
- Principal Investigator
  
  KITAJIMA Mariko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  CHIBA UNIVERSITY
熱帯雨林地域の資源植物を利用した創薬シード分子の検索と化学的研究Principal Investigator
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Medicinal Chemistry on Alkaloids from Plants in Malaya Area
- Principal Investigator
  
  KUBO Akinori
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Chemical pharmacy
- Research Institution
  MEIJI PHARMACEUTICAL UNIVERSITY
Studies on the development of new opioid agonist by utilizing Mitragyna alkaloids as the lead-compoundsPrincipal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  医薬分子機能学
- Research Institution
  Chiba University
Chemical and Biological Studies on Production of Camptothecin-related Molecules by Use of the Domestic Medicinal Resource Plant
- Principal Investigator
  
  AIMI Norio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Chemical Study of Alkaloids in Tropical Medicinal Plants as the Lead-Compounds to Develop New Biologically Functional Molecules.Principal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Chiba University
Medicinal Chemistry on Indole Alkaloids from Thai Medicinal Plants
- Principal Investigator
  
  SAKAI Shin-ichiro
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Investigation and synthetic studies of bioactive Mitragyna alkaloids.Principal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Chiba University
Formation of Alkaloid's by Function of Cultured Plant Cells
- Principal Investigator
  
  AIMI Norio
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Chemical Study on the Indole Alkaloids from Plant Tissue Cultures
- Principal Investigator
  
  SAKAI Shin-ichiro
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Synthetic Studies on the Gelsemium Alkaloids Based on the Biogenetic Speculation
- Principal Investigator
  
  SAKAI Shin-ichiro
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Studies on A Novel Asymmetric Cycloaddition Using Optically Active <alpha> , <beta> -Unsaturated Sulfoxides
- Principal Investigator
  
  KOIZUMI Toru
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toyama Medical & Pharmaceutical University

[Book] 天然物の化学II 自然からの贈り物 (科学のとびら 64)2018
- Author(s)
  高山廣光
- Total Pages
  178
- Publisher
  東京化学同人
- ISBN
  9784807915057
- Data Source
  KAKENHI-PROJECT-16H05094
[Book] トキシコロジー（第3版） (日本毒性学会教育委員会編）（4.7 天然毒性物質)2018
- Author(s)
  高山廣光
- Total Pages
  404
- Publisher
  朝倉書店
- ISBN
  9784254340310
- Data Source
  KAKENHI-PROJECT-16H05094
[Book] アルカロイドの科学 (高山廣光編）（序章 Overview アルカロイド研究の概観, 第9章生合成にヒントを得たアルカロイドの化学合成)2017
- Author(s)
  高山廣光
- Total Pages
  560
- Publisher
  化学同人
- ISBN
  9784759814187
- Data Source
  KAKENHI-PROJECT-16H05094
[Book] The Alkaloids: Chemistry and Biology (Chapter 4: Monoterpenoid Bisindole Alkaloids)2016
- Author(s)
  M. Kitajima, H. Takayama
- Total Pages
  340
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-25293023
[Book] Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source (Chapter 9: Medicinal Chemistry Based on Mitragynine)2015
- Author(s)
  Hiromitsu Takayama and Mariko Kitajima
- Total Pages
  366
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-25293023
[Book] Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source (Chapter 8: Chemistry of Mitragyna Alkaloids)2015
- Author(s)
  Mariko Kitajima and Hiromitsu Takayama
- Total Pages
  366
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-25293023
[Book] Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source (Chapter 8: Chemistry of Mitragyna Alkaloids)2015
- Author(s)
  M. Kitajima, H. Takayama
- Total Pages
  366
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-26670042
[Book] Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source (Chapter 9: Medicinal Chemistry Based on Mitragynine)2015
- Author(s)
  H. Takayama, M. Kitajima
- Total Pages
  366
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-26670042
[Book] Lycopodium Alkaloids: Isolation and Asymmetric Synthesis. Topics in Current Chemistry, "Alkaloid Synthesis"2012
- Author(s)
  Mariko Kitajima and Hiromitsu Takayama
- Publisher
  ed. by H.-J. Knolker, Springer
- Data Source
  KAKENHI-PROJECT-22390019
[Book] パートナー天然物化学2012
- Author(s)
  高山廣光
- Total Pages
  24
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22390019
[Book] Topics in Current Chemistry, "Alkaloid Synthesis"2011
- Author(s)
  M.Kitajima, H.Takayama
- Total Pages
  32
- Publisher
  Lycopodium Alkaloids : Isolation and Asymmetric Synthesis
- Data Source
  KAKENHI-PROJECT-22390019
[Book] パートナー天然物化学(第5章)2007
- Author(s)
  高山廣光(共著)
- Total Pages
  25
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-19310137
[Book] 天然物化学 -植物編-2007
- Author(s)
  高山廣光(共著)
- Total Pages
  10
- Publisher
  アイピーシー
- Data Source
  KAKENHI-PROJECT-18032019
[Book] 天然物化学 -植物編-2006
- Author(s)
  高山廣光 (分担執筆)
- Total Pages
  10
- Publisher
  アイピーシー
- Data Source
  KAKENHI-PROJECT-18032019
[Journal Article] Concise Asymmetric Total Synthesis of Lycopodine and Flabelliformine via Cascade Cyclization Reaction.2019
- Author(s)
  K. Wada, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 60 Pages: 187-190
- DOI
  10.1016/j.tetlet.2018.12.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-17H03993
[Journal Article] Total Syntheses of Pleiocarpamine, Normavacurine, and C-Mavacurine2019
- Author(s)
  K. Sato, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Organic Letters
  
  Volume: 21 Pages: 3342-3345
- DOI
  10.1021/acs.orglett.9b01084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-16K08155, KAKENHI-PROJECT-19K06969, KAKENHI-PROJECT-17H03993
[Journal Article] Asymmetric Total Synthesis of Fawcettimine-Type Lycopodium Alkaloid, Lycopoclavamine-A2019
- Author(s)
  H. Kaneko, S. Takahashi, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 84 Pages: 5645-5654
- DOI
  10.1021/acs.joc.9b00586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-19K06969, KAKENHI-PROJECT-17H03993
[Journal Article] New Indole Alkaloids from Ervatamia cumingiana2019
- Author(s)
  M. Kitajima, S. Nakano, N. Kogure, S. Subhadhirasakul, and H. Takayama
- Journal Title
  
  HETEROCYCLES
  
  Volume: 99 Pages: 213-213
- DOI
  10.3987/com-18-s(f)11
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-19K06969, KAKENHI-PROJECT-17H03993
[Journal Article] New Otonecine-type Pyrrolizidine Alkaloid from Petasites japonicus.2019
- Author(s)
  M. Kitajima, K. Okabe, M. Yoshida, R. Nakabayashi, K, Saito, N. Kogure, and H. Takayama
- Journal Title
  
  J. Nat. Med.
  
  Volume: 73
- DOI
  10.1007/s11418-019-01285-9
- NAID
  40021912727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-17H03993
[Journal Article] Protective Effects of Brain Infarction by N-Acetylcysteine Derivatives.2018
- Author(s)
  Uemura Takeshi、Watanabe Kenta、Ko Kenta、Higashi Kyohei、Kogure Noriyuki、Kitajima Mariko、Takayama Hiromitsu、Takao Koichi、Sugita Yoshiaki、Sakamoto Akihiko、Terui Yusuke、Toida Toshihiko、Kashiwagi Keiko、Igarashi Kazuei
- Journal Title
  
  Stroke
  
  Volume: 49 Pages: 1727-1733
- DOI
  10.1161/strokeaha.118.021755
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06652, KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-16K08244
[Journal Article] Biphenyl Ether and Biphenyl Quinolizidine Lactone Alkaloids from Heimia salicifolia2018
- Author(s)
  M. Kitajima, T. Yanagisawa, M. Tsukahara, Y. Yamaguchi, N. Kogure, R. Kikura-Hanajiri, Y. Goda, O. Iida, Y. Sugimura, N. Kawahara, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume: 74 Pages: 441-452
- DOI
  10.1016/j.tet.2017.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-17H03993
[Journal Article] Asymmetric Total Synthesis and Evaluation of Antitumor Activity of Ophiorrhisine A and Its Derivatives.2018
- Author(s)
  T. Onozawa, M. Kitajima, N. Kogure, and H. Takayama
- Journal Title
  
  J. Org. Chem.
  
  Volume: 83 Pages: 15312-15322
- DOI
  10.1021/acs.joc.8b02554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-17H03993
[Journal Article] Design and Synthesis of 4-Chlorocolchicine-Derived Prodrug Capable of Forming Nanoparticles by Self-assembly2017
- Author(s)
  M. Kitajima, A. Morita, S. Endo, N. Kogure, K. Higashi, K. Moribe, H. Takayama
- Journal Title
  
  Heterocycles
  
  Volume: 95 Pages: 181-186
- DOI
  10.3987/com-16-s(s)51
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-26293023
[Journal Article] Asymmetric Total Synthesis of Pentacyclic Indole Alkaloid Andranginine and Absolute Configuration of Natural Product Isolated from Kopsia arborea2017
- Author(s)
  S. Tooriyama, Y. Mimori, Y. Wu, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Org. Lett.
  
  Volume: 19 Pages: 2722-2725
- DOI
  10.1021/acs.orglett.7b01076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-17H03993
[Journal Article] Synthetic Study of Biphenylquinolizidine Alkaloids I. Asymmetric Total Synthesis of Lasubine I Featuring Organocatalyzed Asymmetric Intramolecular aza-Michael Addition2017
- Author(s)
  T. Hirama, T. Umemura, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Tetrahedron Lett
  
  Volume: 58 Pages: 223-226
- DOI
  10.1016/j.tetlet.2016.12.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-26293023
[Journal Article] A Cyclopeptide and a Tetrahydroisoquinoline Alkaloid from Ophiorrhiza nutans2017
- Author(s)
  T. Onozawa, M. Kitajima, N. Kogure, N. Peerakam, D. Santiarworn, and H. Takayama
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 80 Pages: 2156-2160
- DOI
  10.1021/acs.jnatprod.7b00290
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-17H03993
[Journal Article] Identification of novel glutathione adducts of benzbromarone in human liver microsomes2017
- Author(s)
  N. Cho, K. Kobayashi, M. Yoshida, N. Kogure, H. Takayama, K. Chiba
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 32 Issue: 1 Pages: 46-52
- DOI
  10.1016/j.dmpk.2016.10.412
- NAID
  210000165087
- ISSN
  1347-4367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05094
[Journal Article] Characterization of a Recently Evolved Flavonol-Phenylacyltransferase Gene Provides Signatures of Natural Light Selection in Brassicaceae2016
- Author(s)
  T. Tohge, R. Wendenburg, H. Ishihara, R. Nakabayashi, M.Watanabe, R. Sulpice, R. Hoefgen, H. Takayama, K. Saito M. Stitt, A. R. Fernie
- Journal Title
  
  Nature Communications
  
  Volume: 7 Pages: 12399-12399
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094
[Journal Article] Asymmetric Total Synthesis of Kopsiyunnanine K, a Monoterpenoid Indole Alkaloid with a Rearranged Skeleton2016
- Author(s)
  R. Tokuda, Y. Okamoto, T. Koyama, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Org. Lett.
  
  Volume: 18 Pages: 3490-3493
- DOI
  10.1021/acs.orglett.6b01704
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-26293023
[Journal Article] The First Asymmetric Total Synthesis of Lycoposerramine-R2016
- Author(s)
  H. Ishida, S. Kimura, N. Kogure, M. Kitajima and H. Takayama
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 13 Pages: 7762-7771
- DOI
  10.1039/c5ob00827a
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460005, KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023
[Journal Article] Asymmetric Total Synthesis of Sarpagine-Related Indole Alkaloids Hydroxygardnerine, Hydroxygardnutine, Gardnerine, (E)-16-epi-Normacusine B, and Koumine2016
- Author(s)
  M. Kitajima, K. Watanabe, H. Maeda, N. Kogure, H. Takayama
- Journal Title
  
  Org. Lett.
  
  Volume: 18 Pages: 1912-1915
- DOI
  10.1021/acs.orglett.6b00661
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023, KAKENHI-PROJECT-16H05094
[Journal Article] New Lycopodine-Type Alkaloids from <i>Lycopodium carinatum</i>2016
- Author(s)
  N. Kogure, M. Maruyama, S. Wongseripipatana, M. Kitajima, H. Takayama
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 64 Issue: 7 Pages: 793-799
- DOI
  10.1248/cpb.c16-00171
- NAID
  130005160041
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094
[Journal Article] Kopsiyunnanines L and M, Strychnos-related Monoterpenoid Indole Alkaloids from Yunnan Kopsia arborea2016
- Author(s)
  M. Kitajima, M. Nakazawa, Y. Wu, N. Kogure, R. Zhang, H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume: 72 Pages: 6692-6696
- DOI
  10.1016/j.tet.2016.08.082
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-26293023
[Journal Article] Total Synthesis of Conolidine and Apparicine2016
- Author(s)
  N. Takanashi, K. Suzuki, M. Kitajima, H. Takayama
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 57 Pages: 375-378
- DOI
  10.1016/j.tetlet.2015.12.029
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023
[Journal Article] New Lycopodine-type Alkaloids from Lycopodium carinatum2016
- Author(s)
  N. Kogure, M. Maruyama, S. Wongseripipatana, M. Kitajima, H. Takayama
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: 64 Pages: 0-0
- NAID
  130005160041
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Total Synthesis of (±)-Lycoposerramine-R, a Novel Skeletal Type of Lycopodium Alkaloid.2015
- Author(s)
  H. Ishida, S. Kimura, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume: 71 Pages: 51-56
- DOI
  10.1016/j.tet.2014.11.038
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-25460005, KAKENHI-PROJECT-26293023
[Journal Article] Recent Progress in Total Synthesis of Lycopodium Alkaloids2015
- Author(s)
  H. Takayama
- Journal Title
  
  J. Synth. Org. Chem. Jpn.
  
  Volume: 73 Pages: 1062-1071
- NAID
  130005113515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Boosting Sensitivity in Liquid Chromatography-Fourier Transform Ion Cyclotron Resonance-Tandem Mass Spectrometry for Product Ion Analysis of Monoterpene Indole Alkaloids2015
- Author(s)
  R. Nakabayashi, H. Tsugawa, M. Kitajima, H. Takayama, K. Saito
- Journal Title
  
  Front. Plant. Sci.
  
  Volume: 6
- DOI
  10.3389/fpls.2015.01127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023
[Journal Article] The Cellular Toxicology of Mitragynine, the Dominant Alkaloid of the Narcotic-like Herb, Mitragyna speciosa Korth.2015
- Author(s)
  N. A. Saidin, E. Holmes, H. Takayama, N. J. Gooderham
- Journal Title
  
  Toxicol. Res.
  
  Volume: 4 Pages: 1173-1183
- DOI
  10.1039/c5tx00113g
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Kopsiyunnanines J1 and J2, New Strychnos-type Homo-Monoterpenoid Indole Alkaloids from Kopsia arborea2015
- Author(s)
  M. Kitajima, T. Koyama, Y. Wu, N. Kogure, R. Zhang, and H. Takayama
- Journal Title
  
  Nat. Prod. Commun.
  
  Volume: 10 Pages: 49-51
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Indole alkaloids from Kopsia jasminiflora2014
- Author(s)
  M. Kitajima, M. Anbe, N. Kogure, S. Wongseripipatana, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume: 70 Pages: 9099-9106
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree.2014
- Author(s)
  Yuko Terada, Syunji Horie, Hiromitsu Takayama, Kunitoshi Uchida, Makoto, Tominaga, and Tatsuo Watanabe
- Journal Title
  
  The Journal of Natural Products
  
  Volume: 77 Pages: 285-297
- DOI
  10.1021/np400885u
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J10919, KAKENHI-PROJECT-24580194, KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-25871061
[Journal Article] Iridoids and a Norsesquiterpenoid from the Leaves of Villaria odorata2014
- Author(s)
  M. A. Tan, R. A. U. Villacorta, G. J. D. Alejandro, and H. Takayama
- Journal Title
  
  Nat. Prod. Commun.
  
  Volume: 9 Pages: 1229-1230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Chemical Constituents from Psychotria cadigensis and their chemotaxonomic relevance2014
- Author(s)
  M. A. Tan, G. F. M. Panghulan, M. M. Uy, and H. Takayama
- Journal Title
  
  Am. J. Ess. Oils Nat. Prod.
  
  Volume: 1 Pages: 18-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] A New Sesquiterpenoid from Scaphium macropodum (Miq.) Beumee2014
- Author(s)
  L. M. Ramadhan Al Muqarrabun, Norizan Ahmat, S. Ruzaina S. Aris, Nurdiana Shamsulrijal, Syarul N. Baharum, Rafidah Ahmad, A. Rifki Rosandy, M. Nazip Suratman, and H. Takayama
- Journal Title
  
  Nat. Prod. Res.
  
  Volume: 28 Pages: 597-605
- DOI
  10.1080/14786419.2014.886211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Asymmetric Total Synthesis of Novel Pentacyclic Indole Alkaloid, Kopsiyunnanine E, Isolated from Kopsia arborea2014
- Author(s)
  M. Kitajima, Y. Murakami, N. Takahashi, Y. Wu, N. Kogure, R. Zhang, and H. Takayama
- Journal Title
  
  Org. Lett.
  
  Volume: 16 Pages: 5000-5003
- DOI
  10.1021/ol502265q
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023
[Journal Article] Orally Active Opioid μ/δ Dual Agonist MGM-16, a Derivative of the Indole Alkaloid Mitragynine, Exhibits Potent Antiallodynic Effect on Neuropathic Pain in Mice.2014
- Author(s)
  Matsumoto K, Narita M, Muramatsu N, Nakayama T, Misawa K, Kitajima M, Tashima K, Devi LA, Suzuki T, Takayama H, Horie S.
- Journal Title
  
  J. Pharmacol. Exp. Ther.
  
  Volume: 348 Pages: 383-392
- DOI
  10.1124/jpet.113.208108
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590651, KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293346, KAKENHI-PROJECT-26640015
[Journal Article] Chemotaxonomic relevance of the constituents from the leaves of Rothmannia merrillii2014
- Author(s)
  M. A. Tan, C. N. L. Concepcion1, Grecebio Jonathan D. Alejandro and H. Takayama
- Journal Title
  
  J. Chem. Pharm. Res.
  
  Volume: 6 Pages: 779-781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Biogenetically Inspired Total Syntheses of Lycopodium Alkaloids, (+)-Flabellidine and (–)-Lycodine.2014
- Author(s)
  M. Azuma, T. Yoshikawa, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Pages: 11618-11621
- DOI
  10.1021/ja507016g
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-25460005, KAKENHI-PROJECT-26293023
[Journal Article] Identification of indole alkaloid structural units important for stimulus selective TRPM8 inhibition: SAR study of naturally occurring iboga derivatives.2014
- Author(s)
  Yuko Terada, Mariko Kitajima, Fuyumi Taguchi, Hiromitsu Takayama, Syunji Horie, and Tatsuo Watanabe
- Journal Title
  
  J. Nat. Prod
  
  Volume: 77 Pages: 1831-1838
- DOI
  10.1021/np500235b
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J10919, KAKENHI-PROJECT-24580194, KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023
[Journal Article] 4-Chlorocolchicine Derivatives Bearing a Thiourea Side Chain at the C-7 Position as Potent Anticancer Agents2014
- Author(s)
  H. Nishiyama, M. Ono, T. Sugimoto, T. Sasai, N. Asakawa, S. Ueno, Y. Tominaga, T. Yaegashi, M. Nagaoka, T. Matsuzaki, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Med. Chem. Commun.
  
  Volume: 5 Pages: 452-458
- DOI
  10.1039/c3md00287j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] β-Carboline-type Indole Alkaloid Glycosides from Ophiorrhiza trichocarpon2013
- Author(s)
  M. Kitajima, S. Ohara, N. Kogure, D. Santiarworn, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Pages: 9451-9456
- DOI
  10.1016/j.tet.2013.08.070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Aspidosperma-aspidosperma-type Bisindole Alkaloids from Voacanga africana.2013
- Author(s)
  M. Kitajima, M. Iwai, N. Kogure, R.Kikura-Hanajiri, Y. Goda, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume: 69(2) Pages: 796-801
- DOI
  10.1016/j.tet.2012.10.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] Chemical Conversion of Strychnine into Kopsiyunnanine-I, a New Hexacyclic Indole Alkaloid from Yunnan Kopsia arborea.2012
- Author(s)
  N. Kogure, Y. Suzuki, Y. Wu, M.Kitajima, R. Zhang, and H. Takayama
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 53(48) Pages: 6523-6526
- DOI
  10.1016/j.tetlet.2012.09.078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224, KAKENHI-PROJECT-23790124
[Journal Article] Asymmetric Total Synthesis of an Iboga-Type Indole Alkaloid, Voacangalactone, Newly Isolated from Voacanga africana.2012
- Author(s)
  M. Harada, K. Asaba, M. Iwai, N.Kogure, M. Kitajima, and H.Takayama
- Journal Title
  
  Org. Lett.
  
  Volume: 14(22) Pages: 5800-5803
- DOI
  10.1021/ol3027945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] Secondary Metabolites from Pandanus simplex2012
- Author(s)
  M. A. Tan, M. G. Nonato, M. Kitajima, N. Kogure, and H. Takayama
- Journal Title
  
  Biochem. Syst. Ecol
  
  Volume: 40 Pages: 4-5
- DOI
  10.1016/j.bse.2011.09.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Synthesis and Biological Evaluation of 4-Chlorocolchicine Derivatives as Potent Anticancer Agents with Broad Effective Dosage Ranges.2012
- Author(s)
  H. Nishiyama, M. Ono, T. Sugimoto, T.Sasai, N. Asakawa, T. Matsumoto, T. Yaegashi, M. Nagaoka, T. Matsuzaki, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Med. Chem. Comm.
  
  Volume: 3(12) Pages: 1500-1504
- DOI
  10.1039/c2md20250f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224, KAKENHI-PROJECT-23790124
[Journal Article] New Indole Alkaloids from Melodinus henryi2012
- Author(s)
  M. Kitajima, S. Ohara, N. Kogure, Y.Wu, R. Zhang, and H. Takayama
- Journal Title
  
  Heterocycles
  
  Volume: 85(8) Pages: 1949-1959
- NAID
  40019359686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Syntheses of Fawcettimine-type Lycopodium Alkaloids Utilizing Pauson-Khand Reaction.2012
- Author(s)
  A. Nakayama, M. Kitajima, and H.Takayama
- Journal Title
  
  Synlett
  
  Volume: 23(14) Pages: 2014-2024
- DOI
  10.1055/s-0032-1316680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] Total Synthesis Guided Structure Elucidation of (+)-Psychotetramine2011
- Author(s)
  K. Foo, T. Newhouse, I. Mori, H.Takayama, and P.l S. Baran
- Journal Title
  
  Angew.Chem., Int.Ed.
  
  Volume: 50(12) Pages: 2716-2719
- DOI
  10.1002/anie.201008048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Two New Alkaloids from Crinum asiaticum var. sinicum2011
- Author(s)
  N. Kogure, N. Katsuta, M. Kitajima, and H. Takayama
- Journal Title
  
  Chem. Pharm. Bull
  
  Volume: 59(12) Pages: 1545-1548
- NAID
  130001852130
- URL
  https://www.jstage.jst.go.jp/article/cpb/59/12/59_12_1545/_pdf.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Total Synthesis of Dubiusamine C, A Plausible Minor Alkaloid in Pandanus dubius2011
- Author(s)
  M. A. Tan, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Phillippine Sci. Lett
  
  Volume: 4(2) Pages: 98-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Seven New Monoterpenoid Indole Alkaloids from Gelsemium elegans2011
- Author(s)
  Y. Yamada, M. Kitajima, N. Kogure, S.Wongseripipatana, and H. Takayama
- Journal Title
  
  Chem. Asian J
  
  Volume: 6(1) Pages: 166-173
- DOI
  10.1002/asia.201000538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] Ten New Fawcettimine-related Alkaloids from Three Species of Lycopodium2011
- Author(s)
  K. Katakawa, H. Mito, N. Kogure, M.Kitajima, S. Wongseripipatana, M. Arisawa, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume: 67(35) Pages: 6561-6567
- DOI
  10.1016/j.tet.2011.05.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-23790124
[Journal Article] First Asymmetric Total Synthesis of a Pentacyclic Lycopodium Alkaloid, Huperzine-Q2011
- Author(s)
  A. Nakayama, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Angew. Chem., Int. Ed
  
  Volume: 50(35) Pages: 8025-8028
- DOI
  10.1002/anie.201103550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-23790124
[Journal Article] Metacolchicine, A New Colchicinoid from Sandersonia aurantiaca2011
- Author(s)
  M. Kitajima, A. Tanaka, N. Kogure, and H. Takayama
- Journal Title
  
  Heterocycles
  
  Volume: 83(8) Pages: 1903-1907
- NAID
  40018903002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Design, Synthesis,and Antitumor Activity of4-Halocolchicines and their Pro-drugs Activated by Cathepsin B2011
- Author(s)
  N. Yasobu, M. Kitajima, N. Kogure, Y.Shishido, T. Matsuzaki, M. Nagaoka, and H. Takayama
- Journal Title
  
  ACS Med. Chem. Lett
  
  Volume: 2(5) Pages: 348-352
- DOI
  10.1021/ml100287y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Discovery of Indole Alkaloids with Cannabinoid CB1 Receptor Antagonistic Activity2011
- Author(s)
  M. Kitajima, M. Iwai, R.Kikura-Hanajiri, Y. Goda, M. Iida, H. Yabushita, and H. Takayama
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 21(7) Pages: 1962-1964
- DOI
  10.1016/j.bmcl.2011.02.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Inhibitory Effect of Iboga-type Indole Alkaloids on Capsaicin-induced Contraction in Isolated Mouse Rectum2011
- Author(s)
  M. Lo, K. Matsumoto, M. Iwai, K.Tashima, M. Kitajima, S. Horie, and H. Takayama
- Journal Title
  
  J. Nat. Med
  
  Volume: 65(1) Pages: 157-165
- DOI
  10.1007/s11418-010-0478-6
- NAID
  10029460707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Determination of Absolute Configuration of Trimeric Indole Alkaloid, Psychotrimine, by First Asymmetric Total Synthesis2010
- Author(s)
  N. Takahashi, T. Ito, Y. Matsuda, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Chem.Commun. 46
  
  Pages: 2501-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] 生物活性リコポジウムアルカロイドの探索と不斉合成2010
- Author(s)
  高山廣光
- Journal Title
  
  有合化
  
  Volume: 68(5) Pages: 457-469
- NAID
  10026868803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Two New Aspidosperma Indole Alkaloids from Yunnan Kopsia arborea2010
- Author(s)
  Y. Wu, M. Kitajima, N. Kogure, Y.Wang, R. Zhang, and H. Takayama
- Journal Title
  
  Chem. Pharm. Bull
  
  Volume: 58(7) Pages: 961-963
- NAID
  130000299794
- URL
  https://www.jstage.jst.go.jp/article/cpb/58/7/58_7_961/_pdf.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Synthesis and Biological Evaluation of Indole Alkaloids from Gelsemiumrankinii2010
- Author(s)
  M. Kitajima, H. Kobayashi, N. Kogure, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume: 66(32) Pages: 5987-5992
- DOI
  10.1016/j.tet.2010.06.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] Isolation of Pandamarilactonine-H from the Roots of Pandanus amaryllifolius and Synthesis of epi-Pandamarilactonine-H2010
- Author(s)
  M. A. Tan, M. Kitajima, N. Kogure, M.G. Nonato, and H. Takayama
- Journal Title
  
  J. Nat. Prod
  
  Volume: 73(8) Pages: 1453-1455
- DOI
  10.1021/np1003998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] New Pyrrolidine Alkaloids from the Roots of Pandanus amaryllifolius2010
- Author(s)
  M. A. Tan, M. Kitajima, N. Kogure, M.G. Nonato, and H. Takayama
- Journal Title
  
  Tetrahedron Lett
  
  Volume: 51(31) Pages: 4143-4146
- DOI
  10.1016/j.tetlet.2010.05.150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] A Divergent Approach for the Total Syntheses of Cernuanetype and Quinolizidine-type Lycopodium Alkaloids2009
- Author(s)
  Y. Nishikawa, M. Kitajima, N. Kogure, H. Takayama
- Journal Title
  
  Tetrahedron 65
  
  Pages: 1608-1617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] First Asymmetric Total Syntheses of Fawcettimine-Type Lycopodium Alkaloids, Lycoposerramine-C and Phlegmariurine-A2009
- Author(s)
  A. Nakayama, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Org.Lett. 11
  
  Pages: 5554-5557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Asymmetric Total Syntheses of Cyclic-Nitrone-Containing Phlegmarine-Type Lycopodium Alkaloids, Lycoposerramines-X and-Z2009
- Author(s)
  T. Tanaka, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  J.Org.Chem. 74
  
  Pages: 8675-8680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Rhazinilam and Quebrachamine Derivatives from Yunnan Kopsia arborea2009
- Author(s)
  Y. Wu, M. Suehiro, M. Kitajima, T. Matsuzaki, S. Hashimoto, M. Nagaoka, Masato, R. Zhang, H. Takayama
- Journal Title
  
  J.Nat.Prod. 72
  
  Pages: 204-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Metabolomics-oriented isolation and structure elucidation of 37 compounds including two new anthocyanins from Arabidopsis thaliana.2009
- Author(s)
  Ryo Nakabayashi, Miyako Kusano, Makoto Kobayashi, Takayuki Tohge, Keiko Yonekura-Sakakibara, Noriyuki Kogure, Mami Yamazaki, Mariko Kitajima, Kazuki Saito, Hiromitsu Takayama
- Journal Title
  
  Phytochemistry
  
  Volume: 70 Pages: 1017-1029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] Kopsiyunnanines F and Isocondylocarpines : New Tubotaiwine-type Alkaloids from Yunnan Kopsia arborea2009
- Author(s)
  Y. Wu, M. Kitajima, N. Kogure, Y. Wang, R. Zhang, H. Takayama
- Journal Title
  
  J.Nat.Med. 63
  
  Pages: 283-289
- NAID
  10025826391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] A New Lycopodium Alkaloid, Lycoposerramine-R, with a Novel Sleleton and Three New Fawcettimie-Relted Alkaloids from Lycopodium serratum2009
- Author(s)
  K. Katakawa, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Helv.Chim.Acta 92
  
  Pages: 445-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Metabolomics-oriented isolation and structure elucidation of 37 compounds including two new anthocyanins from Arabidopsis thaliana.2009
- Author(s)
  Ryo Nakabayashi, Miyako Kusano, Makoto Kobayashi, Takayuki Tohge, Keiko Yonekura-Sakakibara, Noriyuki Kogure, Mami Yamazaki, Mariko Kitajima, Kazuki Saito, Hiromitsu Takayama
- Journal Title
  
  Phytochemistry 70
  
  Pages: 1017-1029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] Metabolomics-oriented isolation and structure elucidation of 37 compounds including two new anthocyanins from Arabidopsis thaliana2009
- Author(s)
  Ryo Nakabayashi, Miyako Kusano, Makoto Kobayashi, Takayuki Tohge, Keiko Yonekura-Sakakibara, Noriyuki Kogure, Mami Yamazaki, Mariko Kitajima, Kazuki Saito, Hiromitsu Takayama
- Journal Title
  
  Phytochemistry 70
  
  Pages: 1017-1029
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] First Asymmetric Total Syntheses of Cernuane-Type Lycopodium Alkaloids, Cernuine, and Cermizine D2008
- Author(s)
  Y. Nishikawa, M. Kitajima, H. Takayama
- Journal Title
  
  Org.Lett. 10
  
  Pages: 1987-1990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Comprehensive Flavonol Profiling and Transcriptome Coexpression Analysis Leading to Decoding Gene-Metabolite Correlation in Arabidopsis2008
- Author(s)
  Keiko Yonekura-Sakakibara, Takayuki Tohge, Fumio Matsuda, Ryo Nakabayashi, Hiromitsu Takayama, Rie Niida, Akiko Watanabe-Takahashi, Eri Inoue, Kazuki Saito
- Journal Title
  
  The Plant Cell 20
  
  Pages: 2160-2176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] Two Novel Indole Alkaloids, Kopsiyunnanines A and B, from a Yunnan Kopsia2008
- Author(s)
  Y. Wu, M. Kitajima, N. Kogure, R. Zhang, H. Takayama
- Journal Title
  
  Tetrahedron Lett. 49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] First Total Synthesis of Trimeric Indole Alkaloid, Psychotrimine2008
- Author(s)
  Y. Matsuda, M. Kitajima, H. Takayama
- Journal Title
  
  Org.Lett. 10
  
  Pages: 125-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Comprehensive Flavonol Profiling and Transcriptome Coexpression Analysis Leading to Decoding Gene-Metabolite Correlation in Arabidopsis.2008
- Author(s)
  Keiko Yonekura-Sakakibara, Takayuki Tohge, Fumio Matsuda, Ryo Nakabayashi, Hiromitsu Takayama, Rie Niida, Akiko Watanabe-Takahashi, Eri Inoue, Kazuki Saito
- Journal Title
  
  Plant Cell 20
  
  Pages: 2160-2176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] MGM-9 [(E)-Methyl 2-(3-ethyl-7a, 12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo [2,3-a] quinolizin-2-yl)-3-methoxyacrylate], a Derivative of the Indole Alkaloid Mitragynine : A Novel Dual-acting μ-and κ-Opioid Agonist with Potent Antinociceptive and Weak Rewarding Effects in Mice2008
- Author(s)
  K. Matsumoto, H. Takayama, M. Narita, A. Nakamura, M. Suzuki, T. Suzuki, T. Murayama, S. Wongseripipatana, K. Misawa, M. Kitajima, K. Tashima, S. Horie
- Journal Title
  
  Neuropharmacology 55
  
  Pages: 154-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Design,synthesis,and biological evaluation of tricyclic heterocycle-tetraamine conjugates as potent NMDA channel blockers2007
- Author(s)
  H.Takayama, et. al.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 17
  
  Pages: 4729-4732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Asymmetric Total Syntheses of Two Phlegmarine-Type Alkaloids, Lycoposerramines-V and -W, Newly Isolated from Lycopodium serratum2007
- Author(s)
  T. Shigeyama, K. Katakawa, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Org.Lett. 9
  
  Pages: 4069-4072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Design, Synthesis and Biological Evaluation of Tricyclic Heterocycle-Tetraamine Conjugates as Potent NMDA Channel Blockers2007
- Author(s)
  H. Takayama, Y. Yaegashi, M. Kitajima, X. Han, K. Nishimura, S. Okuyama, K. Igarashi
- Journal Title
  
  Bioorg.Med.Chem.Lett. 17
  
  Pages: 4729-4732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Fawcettimine-Related Alkaloids from Lycopodium serratum2007
- Author(s)
  K. Katakawa, A. Nozoe, N. Kogure, M. Kitajima, M. Hosokawa, H. Takayama
- Journal Title
  
  J.Nat.Prod. 70
  
  Pages: 1024-1028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Application to the Preparation of Potent Opioid Receptor Agonists with a Corynanthe Skeleton.2006
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Org.Lett. 8
  
  Pages: 5705-5708
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Application to the Preparation of Potent Opioid Receptor Agonists with Corynanthe Skeleton.2006
- Author(s)
  H.Takayama
- Journal Title
  
  Organic Letters 8・25
  
  Pages: 5705-5708
- Data Source
  KAKENHI-PROJECT-18032019
[Journal Article] New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Application to the Preparation of Potent Opioid Receptor Agonists with a Corynanthe Skeleton.2006
- Author(s)
  H.Takayama, et al.
- Journal Title
  
  Org.Lett. 8・25
  
  Pages: 5705-5708
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Application to the Preparation of Potent Opioid Receptor Agonists with a Corynanthe Skeleton.2006
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Org. Lett. 8・25
  
  Pages: 5705-5708
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] Chemistry of Indole Alkaloids Related to the Corynanthe-Type from Uncaria, Nauclea and Mitragyna Plants.2005
- Author(s)
  H.Takayama
- Journal Title
  
  Current Organic Chemistry 9・15
  
  Pages: 1445-1464
- Data Source
  KAKENHI-PROJECT-17035016
[Journal Article] Determination of absolute configuration of Pandanus alkaloid, pandamarilactonine-A, by first asymmetric total synthesis.2005
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Tetrahedron Lett. 46・35
  
  Pages: 5795-5797
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] Chemistry and pharmacology of analgesic indole alkaloids from Rubiaceous plant, Mitragyna speciosa.2004
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages: 916-928
- NAID
  110003615687
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] A new 9-methoxyyohimbine-type alkaloid from Mitragyna africanus.2004
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages: 359-361
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Isolation, Structure Elucidation, and Total Synthesis of Two New Chimonanthus Alkaloids, Chimonamidine and Chimonanthidine.2004
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Tetrahedron 60・4
  
  Pages: 893-900
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] A New 9-Methoxyyohimbine-Type Indole Alkaloid from Mitragyna africanus.2004
- Author(s)
  Takayama H.
- Journal Title
  
  Chem.Pharm.Bull. 52(3)
  
  Pages: 359-361
- NAID
  110003615565
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] New Type of Trimeric and Pentameric Indole Alkloids from Psychotria rostrata.2004
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Organic Lett. 6・17
  
  Pages: 2945-2948
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] A New 9-Methoxyyohimbine-Type Alkaloid from Mitragyna africanus.2004
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Chem.Pharm.Bull. 52・3
  
  Pages: 359-361
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] Camptothecin production by in vitro cultures of Ophiorrhiza liukiuensis and O. kurolwai2004
- Author(s)
  Asano, T., Watase, I., Sudo, H., Kitajima, M., Takayama, H., Aimi, N., Yamazaki, M., Saito, K.
- Journal Title
  
  Plant Biotech 21
  
  Pages: 275-281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310137
[Journal Article] A new 9-methoxyyohimbine-type alkaloid from Mitragyna africanus.2004
- Author(s)
  Takayama, H.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages: 359-361
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Chemistry and Pharmacology of Analgesic Indole Alkaloids from the Rubiaceous Plant, Mitragyna speciosa.2004
- Author(s)
  Takayama H.
- Journal Title
  
  Chem.Pharm.Bull. 52(8)
  
  Pages: 916-9128
- NAID
  110003615687
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Chemistry and pharmacology of analgesic indole alkaloids from Rubiaceous plant, Mitragyna speciosa.2004
- Author(s)
  Takayama, H.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages: 916-928
- NAID
  110003615687
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Biosynthesis of camptothecin. In silico and in vivo tracer study from [1-^<13> C] glucose2004
- Author(s)
  Yamazaki, Y., Kitajima, M., Arita, M., Takayama, H., Sudo, H., Yamazaki, M., Aimi N. and Saito, K.
- Journal Title
  
  Plant Physiol 134
  
  Pages: 161-170
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310137
[Journal Article] First asymmetric total synthesis of Us-7 and-8,novel D-seco Corynanthe-type oxindole alkaloids from Uncaria attenuata.2003
- Author(s)
  Takayama, H.
- Journal Title
  
  Org.Lett. 5
  
  Pages: 2967-2970
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] First asymmetric total synthesis of Us-7and -8, novel D-seco Corynanthe-type oxindole alkaloids from Uncaria attenuata.2003
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Org.Lett. 5
  
  Pages: 2967-2970
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] 未利用薬用資源植物から創薬シード分子を探す2002
- Author(s)
  高山廣光
- Journal Title
  
  化学と生物 40
  
  Pages: 676-682
- NAID
  10012132207
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Studies on the synthesis and opioid agonistic activities of mitragynine-related alkaloids. Discovery of opioid agonists structurally different from other opioid ligands2002
- Author(s)
  Takayama, H.
- Journal Title
  
  J.Med.Chem. 49
  
  Pages: 1949-1956
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Studies on the synthesis and opioid agonistic activities of mitragynine-related alkaloids. Discovery of opioid agonists structurally different from other opioid ligands.2002
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  J.Med.Chem. 49
  
  Pages: 1949-1956
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Search for the seeds molecules for drug development from the untapped medicinal plant resources.2002
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Chemistry and Biology 40
  
  Pages: 676-682
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Formation of an unusual dimeric compound by lead tetraacetate oxidation of a Corynanthe-type indole alkaloid, mitragynine.2002
- Author(s)
  Takayama, H.
- Journal Title
  
  Chem.Pharm.Bull. 50
  
  Pages: 960-963
- NAID
  110003616278
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Formation of an unusual dirneric compound by lead tetraacetate oxidation of a Corynanthe-type indole alkaloid, mitragynine.2002
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Chem.Pharm.Bull. 50
  
  Pages: 960-963
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Patent] Opioid Analgesic2016
- Inventor(s)
  高山廣光
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-04-26
- Overseas
- Data Source
  KAKENHI-PROJECT-26670042
[Patent] オピオイド鎮痛剤 (Opioid Analgesic)2016
- Inventor(s)
  高山廣光
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016
- Acquisition Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16H05094
[Patent] オピオイド鎮痛剤2016
- Inventor(s)
  高山廣光
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-545005
- Filing Date
  2016-04-28
- Data Source
  KAKENHI-PROJECT-16H05094
[Patent] オピオイド鎮痛剤2016
- Inventor(s)
  高山廣光
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-545005
- Filing Date
  2016-04-28
- Data Source
  KAKENHI-PROJECT-26670042
[Patent] Opioid Analgesic2016
- Inventor(s)
  高山廣光
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-04-26
- Overseas
- Data Source
  KAKENHI-PROJECT-16H05094
[Patent] 特許2014
- Inventor(s)
  高山廣光
- Industrial Property Rights Holder
  高山廣光
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-28
- Overseas
- Data Source
  KAKENHI-PROJECT-25293023
[Patent] Indole Alkaloid Derivatives Having Opioid Receptor Antagonistic Effect, and Therapeutic Compositions and Methods Relating to Same2014
- Inventor(s)
  H. Takayama, M. Kitajima et al
- Industrial Property Rights Holder
  H. Takayama, M. Kitajima et al
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-11
- Overseas
- Data Source
  KAKENHI-PROJECT-25293023
[Patent] 特許2014
- Inventor(s)
  高山廣光
- Industrial Property Rights Holder
  高山廣光
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-28
- Overseas
- Data Source
  KAKENHI-PROJECT-26670042
[Patent] オピオイド鎮痛剤2013
- Inventor(s)
  高山廣光
- Industrial Property Rights Holder
  高山廣光
- Industrial Property Rights Type
  特許
- Filing Date
  2013-10-29
- Data Source
  KAKENHI-PROJECT-25293023
[Patent] Compound Having Activity of Blocking NMDA Receptor Channel, and Pharmaceutical Agent Using the Same.2012
- Inventor(s)
  K. Igarashi, H. Takayama
- Industrial Property Rights Holder
  K. Igarashi, H. Takayama
- Industrial Property Rights Type
  特許
- Filing Date
  2012-05-14
- Overseas
- Data Source
  KAKENHI-PROJECT-22390019
[Patent] Indole Alkaloid Derivatives Having Opioid Receptor Antagonistic Effect, and Therapeutic Compositions and Methods Relating to Same.2012
- Inventor(s)
  H. Takayama, M. Kitajima, et al.
- Industrial Property Rights Holder
  H. Takayama, M. Kitajima, et al.
- Industrial Property Rights Type
  特許
- Filing Date
  2012-08-21
- Acquisition Date
  2012-08-21
- Overseas
- Data Source
  KAKENHI-PROJECT-22390019
[Patent] Colchicine Derivatives2011
- Inventor(s)
  H. Takayama et al.
- Industrial Property Rights Holder
  千葉大学他
- Filing Date
  2011-02-24
- Data Source
  KAKENHI-PROJECT-22390019
[Patent] Colchicine Derivatives.2011
- Inventor(s)
  H.Takayama, etal.
- Industrial Property Rights Holder
  千葉大学, 他
- Filing Date
  2011-02-24
- Overseas
- Data Source
  KAKENHI-PROJECT-22390019
[Patent] ボアカンガアフリカーナより得られるカンナビノイド受容体薬およびその利用2011
- Inventor(s)
  合田幸広, 花尻瑠理, 高山廣光, 他
- Industrial Property Rights Holder
  千葉大学他
- Filing Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22390019
[Patent] コルヒチン誘導体2010
- Inventor(s)
  高山廣光, 他
- Industrial Property Rights Holder
  千葉大学, 他
- Filing Date
  2010-08-20
- Data Source
  KAKENHI-PROJECT-22390019
[Patent] コルヒチン誘導体2010
- Inventor(s)
  高山廣光,, 他
- Industrial Property Rights Holder
  千葉大学他
- Filing Date
  2010-08-20
- Data Source
  KAKENHI-PROJECT-22390019
[Patent] コルヒチン誘導体2010
- Inventor(s)
  高山廣光, 八十歩直子, 北島満里子, 八重樫隆, 松崎健, 長岡正人, 橋本秀介
- Industrial Property Rights Holder
  千葉大学, 株式会社ヤクルト本社
- Filing Date
  2010-03-03
- Data Source
  KAKENHI-PROJECT-19310137
[Patent] オピオイド鎮痛剤2008
- Inventor(s)
  高山廣光、北島満里子、松本健次郎、堀江俊治
- Industrial Property Rights Holder
  千葉大学、城西国際大学
- Filing Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19310137
[Patent] Indole Alkaloid Derivatives Having Opioid Receptor Agonisitc Effect, and Therapeutic Compositions and Methods Relating Same.2008
- Inventor(s)
  高山廣光、北島満里子、松本健次郎、堀江俊治
- Industrial Property Rights Holder
  千葉大学、城西国際大学
- Filing Date
  2008-11-07
- Overseas
- Data Source
  KAKENHI-PROJECT-19310137
[Patent] オピオイド性鎮痛剤2008
- Inventor(s)
  高山廣光, 北島満里子, 松本健次郎, 堀江俊治
- Industrial Property Rights Holder
  千葉大学, 城西国際大学
- Filing Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19310137
[Patent] Indole Alkaloid Derivatives Having Opioid Receptor Agonistic Effect, and Therapeutic Compositions and Methods Relating to Same2008
- Inventor(s)
  Hiromitsu Takayama, Mariko Kitajima, Kenjiro Matsumoto, Syunji Horie
- Industrial Property Rights Holder
  千葉大学, 城西国際大学
- Filing Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-19310137
[Patent] Compound having activity of blocking NMDA receptor channel, and pharmaceutical agent using the same2007
- Inventor(s)
  Igarashi, K., Takayama, H.
- Industrial Property Rights Holder
  Kozai, T.
- Filing Date
  2007-04-26
- Overseas
- Data Source
  KAKENHI-PROJECT-19310137
[Patent] Compound Having Activity of Blocking NMDA Receptor Channel, and Pharmaceutical Agent Using the Same2007
- Inventor(s)
  Kazuei Igarashi, Hiromitsu Takayama
- Industrial Property Rights Holder
  千葉大学
- Filing Date
  2007-04-26
- Data Source
  KAKENHI-PROJECT-19310137
[Patent] Indole Alkaloid Derivatives Having Opioid Receptor Agonistic Effect and Therapeutic Comp ositions and Methods Relating To Same.2007
- Inventor(s)
  Takayama, Hら
- Industrial Property Rights Holder
  Kozai, T.
- Filing Date
  2007-01-18
- Overseas
- Data Source
  KAKENHI-PROJECT-18032019
[Patent] オピオイド性鎮痛剤2007
- Inventor(s)
  高山廣光, 北島満里子, 松本健次郎, 堀江俊治
- Industrial Property Rights Holder
  千葉大学, 城西国際大学
- Filing Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] (+)-カリカンチンを用いた新規有機不斉触媒の開発研究2020
- Author(s)
  山西恭輔、小暮紀行、北島満里子、高山廣光
- Organizer
  日本薬学会第１４０年会
- Data Source
  KAKENHI-PROJECT-17K19474
[Presentation] Pyrrolizidine アルカロイド Otonecine の不斉全合成研究2019
- Author(s)
  金澤修平, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] ゲルセミウムアルカロイドGelsefuranidine及び関連アルカロイドの不斉全合成2019
- Author(s)
  齊藤惇, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] アカネ科Ophiorrhiza pumila毛状根の成分探索研究2019
- Author(s)
  門間古都, 北島満里子, 小暮紀行, 中谷泰貴, Amit Rai, 山崎真巳, 斉藤和季, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Claisen転位反応を鍵段階とした新規インドールアルカロイドKopsiyunnanine Nの不斉全合成研究2019
- Author(s)
  森田幸輝, 戸田遥介, 佐々木みゆき,小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] インドールアルカロイドStrictamineの生合成を模擬した不斉全合成研究2019
- Author(s)
  佐藤圭悟, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Iboga型インドールアルカロイド類の網羅的不斉全合成研究2019
- Author(s)
  多田隈太輝, 宮路和則, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 3,3-二置換ピペリジン骨格をもつLeucomidine Aの不斉全合成研究2019
- Author(s)
  冨永翔太, 森田暁洋, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K19474
[Presentation] 転位型新規リコポジウムアルカロイド Huperzine H の不斉全合成2019
- Author(s)
  小暮紀行, Kaewsri Wilailak, 早乙女航, 北島満里子, Thongsornkleeb Charnsak, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Ophiorrhiza pumila含有新規ヘテロヨヒンビン型インドールアルカロイドON-9の単離と全合成研究2019
- Author(s)
  小野沢忠吉, 北島満里子, 小暮紀行, Peerakam Nichakan, Santiarworn Dammrong, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 3,3-二置換ピペリジン骨格をもつLeucomidine Aの不斉全合成研究2019
- Author(s)
  冨永翔太, 森田暁洋, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Lycopodiumアルカロイド Lycopodineの生合成経路を模擬した不斉全合成2019
- Author(s)
  和田健太郎, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Lycopodiumアルカロイド Lycopodine の生合成経路を模擬した不斉全合成2018
- Author(s)
  和田健太郎, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Gelsedine 型ゲルセミウムアルカロイドの全合成研究2018
- Author(s)
  齊藤惇, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 不斉Claisen転位反応を鍵段階とした新規インドールアルカロイド Kopsiyunnanine N の不斉全合成研究2018
- Author(s)
  戸田遥介, 德田涼子, 佐々木みゆき, 高橋伸明, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 新規二量体型ヒガンバナ科アルカロイドAlbifloramineの不斉全合成研究2018
- Author(s)
  林弥沙, 中野秋香, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Ophiorrhiza nutans含有新規シクロファン型環状ペプチドOphiorrhisine Aの単離と不斉全合成による構造決定2018
- Author(s)
  小野沢忠吉, 北島満里子, 小暮紀行, Nichakan Peerakam, Dammrong Santiarworn, 高山廣光
- Organizer
  第60回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 有機分子触媒を用いた光学活性 3,3-二置換ピペリジン骨格構築法の開発と天然物合成への応用2018
- Author(s)
  森田暁洋, 片山健, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Akuammiline 型インドールアルカロイドStrictamineの生合成を模擬した不斉全合成研究2018
- Author(s)
  佐藤圭悟, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Iboga 型インドールアルカロイド Voacangine 類及び Catharanthine の不斉全合成研究2018
- Author(s)
  宮路和則, 原口敬佑, 和田凌太, 浅場絢ヌネッツ, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Kopsia arborea含有新規アルカロイドの構造解析2018
- Author(s)
  五十嵐舞, 北島満里子, Yuqui Wu, 小暮紀行, Rongping Zhang, 高山廣光
- Organizer
  日本生薬学会第65回年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 新規 Kopsiaアルカロイド Kopsiyunnanine L の生合成経路にヒントを得た全合成研究2018
- Author(s)
  福田勇斗, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 有機分子触媒を用いた光学活性 3,3-二置換ピペリジン骨格構築法の開発と天然物合成への応用2018
- Author(s)
  森田暁洋, 片山健, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K19474
[Presentation] エキウム属植物含有ピロリジジンアルカロイドの探索及びPAsの新規分析法の開発研究2018
- Author(s)
  吉田恵, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本生薬学会第65回年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] TRPV1アンタゴニスト活性を有するVoacangine類の不斉全合成研究2018
- Author(s)
  原口敬佑, 宮路和則, 和田凌太, 浅場絢ヌネッツ, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第54回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 14-Hydroxygelsedilam及び、関連アルカロイドの不斉全合成研究2018
- Author(s)
  齊藤惇, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第44回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] シニクイチ (Heimia salicifolia) 含有新規ビフェニルキノリチジンアルカロイド類の不斉全合成研究2018
- Author(s)
  川端遥, 平間拓, 北島満里子, 小暮紀行, 高山廣光
- Organizer
  第22回天然薬物の開発と応用シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] パラシクロファン型新規環状テトラペプチドOphiorrhisine Aの不斉全合成および誘導体合成2018
- Author(s)
  小野沢忠吉, 北島満里子, 小暮紀行, Peerakam Nichakan, Santiarworn Dammrong, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Fawcettimine型リコポジウムアルカロイドLycopoclavamine-A及び Lycophlegmarinone の不斉全合成研究2018
- Author(s)
  金子弘樹, 高橋駿介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第44回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] ミソハギ科植物含有新規ビフェニルキノリチジンアルカロイド類の不斉全合成研究2018
- Author(s)
  川端遥, 平間拓, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Pyrrolizidine アルカロイド Otonecine の不斉全合成研究2018
- Author(s)
  金澤修平, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 生物活性アルカロイドの探索・全合成と医薬化学研究2018
- Author(s)
  高山廣光
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Fawcettimine型リコポジウムアルカロイドLycopoclavamine-Aの不斉全合成2018
- Author(s)
  金子弘樹, 高橋駿介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] キョウチクトウ科 Kopsia arborea 含有新規インドールアルカロイド Kopsiyunnanines K, L, M の構造と Andranginine の絶対立体配置2017
- Author(s)
  小暮紀行, 徳田涼子, 通山紫乃, 中澤麻衣子, 小山徹也, 岡本佳樹, 三森雄二, Yuqui Wu, Rong-Ping Zhang, 北島満里子, 高山廣光
- Organizer
  第59回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 有機分子触媒を用いた立体選択的 3,3-二置換ピペリジン骨格構築法の開発と天然物合成への応用2017
- Author(s)
  森田暁洋, 片山健, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-17K19474
[Presentation] Bioinspired Total Syntheses of Alkaloids Isolated from Medicinal Plants2017
- Author(s)
  H. Takayama
- Organizer
  Frontiers on Medicinal Chemistry
- Place of Presentation
  Bern（スイス）
- Year and Date
  2017-02-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] インドールアルカロイドandranginineの不斉全合成と天然物の絶対立体配置について2017
- Author(s)
  通山紫乃, 三森雄二, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Fawcettimine型リコポジウムアルカロイドLycopoclavamine-Aの不斉全合成研究2017
- Author(s)
  金子弘樹, 高橋駿介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] LycopodiumアルカロイドLycopodine類の生合成経路を模擬した不斉全合成研究2017
- Author(s)
  和田健太郎, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 植物系危険ドラッグ・シニクイチHeimia salicifolia含有新規生物活性アルカロイドの探索研究2017
- Author(s)
  塚原真理, 柳沢朋美, 山口恭加, 小暮紀行, 北島満里子, 杉村康司, 飯田修, 川原信夫, 花尻(木倉)瑠理, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 不斉Claisen転位反応を鍵段階とした新規インドールアルカロイドKAM1の不斉全合成研究2017
- Author(s)
  戸田遥介, 德田涼子, 佐々木みゆき, 高橋伸明, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 有機分子触媒を用いた立体選択的3,3-二置換ピペリジン骨格構築法の開発2017
- Author(s)
  森田暁洋, 片山健, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Kopsia jasminiflora含有新規Eburnane型アルカロイド類の不斉全合成研究2017
- Author(s)
  仲村修平, 長尾昂紀, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 新規二量体型アルカロイドLA-1の全合成研究2017
- Author(s)
  林弥沙, 中野秋香, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 生合成経路模擬の連続的環化反応を鍵とするLycopodineの不斉全合成研究2017
- Author(s)
  和田健太郎, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  創薬懇話会2017 in 加賀
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] キョウチクトウ科Ervatamia cumingiana含有新規インドールアルカロイドの構造解析2017
- Author(s)
  中野峻平, 小暮紀行, 北島満里子, Sanan Subhadhirasakul, 高山廣光
- Organizer
  日本生薬学会第64回年会
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Akuammiline 型インドールアルカロイド Strictamine の形式全合成2017
- Author(s)
  佐藤圭悟, 高梨憲幸, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 加齢による脳梗塞悪化とアクロレインの関係並びに新規脳保護薬の開発2017
- Author(s)
  渡辺健太, 植村武史, 東恭平, 小暮紀行, 北島満里子, 高山廣光, 高尾浩一, 杉田義昭, 西村和洋, 五十嵐一衛, 戸井田敏彦
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] ミソハギ科植物含有新規ビフェニルキノリジジンアルカロイド類の不斉全合成研究2017
- Author(s)
  川端遥, 平間拓, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 有機分子触媒を用いた立体選択的 3,3-二置換ピペリジン骨格構築法の開発と天然物合成への応用2017
- Author(s)
  森田暁洋, 片山健, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Iboga型インドールアルカロイドVoacangine類の不斉全合成研究2017
- Author(s)
  和田凌太, 浅場絢ヌネッツ, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Ophiorrhiza nutans含有新規環状テトラペプチドON16の単離と不斉全合成研究2017
- Author(s)
  小野沢忠吉, 小暮紀行, 北島満里子, SANTIARWORN DAMMRONG, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] パラシクロファン型新規環状テトラペプチドOphiorrhisine Aの不斉全合成2017
- Author(s)
  小野沢忠吉, 北島満里子, 小暮紀行, Nichakan Peerakam, Dammrong Santiarworn, 高山廣光
- Organizer
  第53回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Kopsia arborea 含有新規 Strychnos 型関連インドールアルカロイドの構造解析2016
- Author(s)
  北島満里子, 中澤麻衣子, Yuqui Wu, 小暮紀行, Rongping Zhang, 高山廣光
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 天然物の生合成に関する知見・考察をアルカロイド全合成に活かす2016
- Author(s)
  高山廣光
- Organizer
  徳島大学創薬先端合成化学セミナー
- Place of Presentation
  徳島大学薬学部（徳島県徳島市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 16-(R)-Hydroxysempervirineの不斉全合成2016
- Author(s)
  鎌谷美友紀, 山田洋介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 生物活性アルカロイドの探索と精密構造解析2016
- Author(s)
  高山廣光
- Organizer
  理研シンポジウム: 高磁場・高感度NMR利活用促進のための天然物関連シンポジウム2016
- Place of Presentation
  理化学研究所・横浜キャンパス（神奈川県横浜市）
- Year and Date
  2016-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] アカネ科植物Ophiorrhiza nutans含有成分の探索と化学的研究2016
- Author(s)
  小野沢忠吉, 小暮紀行, 北島満里子, Dammrong Santiarworn, 高山廣光
- Organizer
  第21回天然薬物の開発と応用シンポジウム
- Place of Presentation
  千葉大学薬学部120周年記念講堂（千葉県千葉市）
- Year and Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Kopsia arborea 含有インドールアルカロイドArboflorineの不斉全合成研究2016
- Author(s)
  真鍋ひとみ, 村上洋介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第21回天然薬物の開発と応用シンポジウム
- Place of Presentation
  千葉大学薬学部120周年記念講堂（千葉県千葉市）
- Year and Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] ミソハギ科植物含有ビフェニルキノリジジンアルカロイド類の不斉全合成研究2016
- Author(s)
  平間拓, 梅村隆之, 柳沢朋美, 山口恭加, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKopsiyunnanine Kの不斉全合成2016
- Author(s)
  徳田涼子, 岡本佳樹, 小山徹也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Iboga型インドールアルカロイドVoacangine類の全合成研究2016
- Author(s)
  和田凌太, 浅場絢ヌネッツ, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第42回反応と合成の進歩シンポジウム
- Place of Presentation
  静岡市清水文化会館マリナート（静岡県静岡市）
- Year and Date
  2016-11-08
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 五環性モノテルペノイドインドールアルカロイドAndranginineの不斉全合成研究2016
- Author(s)
  通山紫乃, 三森雄二, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] タイ産アカネ科 Ophiorrhiza nutans 含有アルカロイド成分探索2016
- Author(s)
  小野沢忠吉, 小暮紀行, 北島満里子, Santiarworn Dammrong, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Bioinspired Syntheses of Alkaloids Isolated from Medicinal Plants2016
- Author(s)
  H. Takayama
- Organizer
  The 9th CSP-KSP-JSP Joint Symposium on Pharmacognosy & 2016 Annual Conference of Committee of Chinese Traditional and Natural Medicines, Chinese Pharmaceutical Association
- Place of Presentation
  上海（中国）
- Year and Date
  2016-05-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] KopsiaアルカロイドArboflorineの不斉全合成研究2016
- Author(s)
  真鍋ひとみ, 村上洋介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Akuammiline型インドールアルカロイドの全合成研究2016
- Author(s)
  高梨憲幸, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 変形Fawcettimine型LycopodiumアルカロイドHuperzine Hの不斉全合成研究2016
- Author(s)
  部家有紗, 早乙女航, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKAM1の不斉全合成研究2016
- Author(s)
  德田涼子, 高橋伸明, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] ヒガンバナアルカロイド生合成仮想中間体の一斉分析系の開発2015
- Author(s)
  小野寺蓮, 浅野孝, 小暮紀行, 高山廣光, 藤井勲
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Lycodine 型アルカロイド類の生合成経路を模擬した効率的不斉全合成研究2015
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第57回天然有機化合物討論会
- Place of Presentation
  横浜
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKopsiyunnanine Kのスペクトル解析及び不斉全合成による構造決定2015
- Author(s)
  北島満里子, 岡本佳樹, 小山徹也, Yuqiu Wu, 小暮紀行, Rongping Zhang, 高山廣光
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 非オピオイド様鎮痛活性を有する C5-nor stemmadenine 型インドールアルカロイドの全合成研究2015
- Author(s)
  高梨憲幸, 鈴木健太, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  千葉
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 金触媒環化反応を用いたサルパギン型インドールアルカロイドの不斉全合成2015
- Author(s)
  渡辺慧介, 前田博行, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第41回反応と合成の進歩シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKAM1の不斉全合成研究2015
- Author(s)
  德田涼子, 高橋伸明, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 生物活性アルカロイドの探索・合成・創薬化学研究2015
- Author(s)
  高山廣光
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 五環性モノテルペノイドインドールアルカロイド Andranginine の不斉全合成研究2015
- Author(s)
  通山紫乃, 三森雄二, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  千葉
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] オクトレオチドユニットを配したコルヒチン系ダブルプロドラッグ化合物の創製研究2015
- Author(s)
  北島満里子, 遠藤慎平, 森田暁洋, 小暮紀行, 高山廣光
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  千葉
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Fawcettimine型リコポジウムアルカロイドLycopoclavamine-Aの不斉全合成研究2015
- Author(s)
  高橋駿介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規骨格Lycopodiumアルカロイド(–)-Lycoposerramine-Rの不斉全合成2015
- Author(s)
  石田寛明, 木村真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 金触媒環化反応を用いたSarpagine型インドールアルカロイドの不斉全合成研究2015
- Author(s)
  渡邉慧介, 前田博行, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] ヒカゲノカズラ科 Lycopodium carinatum 含有アルカロイドの探索研究2015
- Author(s)
  丸山萌, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] キョウチクトウ科植物Kopsia arborea含有新規インドールアルカロイドKopsiyunnanines E, I, J1, J22014
- Author(s)
  村上洋介, 小山徹也, 鈴木悠太, 高橋伸明, Yuqui Wu , 小暮紀行, Rongping Zhang, 北島満里子, 高山廣光
- Organizer
  第56回天然有機化合物討論会
- Place of Presentation
  高知
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Lycopodiumアルカロイド Lycodineの生合成経路を模擬した短段階不斉全合成2014
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第105回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-06-10
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 温度感受性TRPチャネルアンタゴニスト活性を有するVoacangine関連化合物の全合成研究と構造活性相関2014
- Author(s)
  北島満里子，寺田祐子，田口芙悠美，浅場絢ヌネッツ，小暮紀行，渡辺達夫，高山廣光
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規骨格 Lycopodium アルカロイド Lycoposerramine-R の不斉全合成研究2014
- Author(s)
  石田寛明, 木村真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第40回反応と合成の進歩シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2014-11-10
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Voacangine類縁化合物を用いた構造―活性相関研究化学アゴニスト選択的TRPM8阻害に重要な構造の同定2014
- Author(s)
  寺田祐子, 北島満里子, 田口芙悠美, 高山廣光, 堀江俊治, 渡辺達夫
- Organizer
  第29回日本香辛料研究会学術講演会
- Place of Presentation
  札幌
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] キョウチクトウ科Kopsia arborea含有インドールアルカロイドの探索2014
- Author(s)
  北島満里子, 小山徹也, Yuqiu Wu, 小暮紀行, Rongping Zhang, 高山廣光
- Organizer
  日本生薬学会第61回年会
- Place of Presentation
  福岡
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 生物活性天然物の探索と全合成-創薬研究に向けて2013
- Author(s)
  高山廣光
- Organizer
  創薬懇話会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Bioinspired Short Asymmetric Total Synthesis of Lycopodium Alkaloid, (-)-Lycodine2013
- Author(s)
  M. Azuma, N. Kogure, M. Kitajima, H. Takayama
- Organizer
  3rd Junior International Conference on Cutting-Edge Organic Chemistry in Asia
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規骨格LycopodiumアルカロイドLycoposerramine-Rの不斉全合成研究2013
- Author(s)
  石田寛明,木村真也,小暮紀行,北島満里子,高山廣光
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2012
- Author(s)
  高山廣光
- Organizer
  明治薬科大学ハイテクリサーチセンター平成20-24年度研究成果発表会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2012
- Author(s)
  高山廣光
- Organizer
  有機合成2月セミナー「有機合成のニュートレンド2012」
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] アルカロイドの探索と全合成研究から得られるもの2012
- Author(s)
  高山廣光
- Organizer
  第47回天然物化学談話会
- Place of Presentation
  熊本
- Year and Date
  2012-07-04
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Pauson-Khand反応を基盤としたFawcettimineの不斉全合成研究2012
- Author(s)
  中山淳,小暮紀行,北島満里子,高山廣光
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索から全合成へ. そして創薬研究へ2012
- Author(s)
  高山廣光
- Organizer
  平成24年度前期（春期）有機合成化学講習会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 栃木県産Lycopodiumserratum含有アルカロイドの成分探索2012
- Author(s)
  池城沙耶子,北島満里子,小暮紀行,片川和明,高山廣光
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 有機合成化学の醍醐味-戦略的アプローチの最前線-2012
- Author(s)
  高山廣光
- Organizer
  生物活性アルカロイドの探索から全合成へ.そして創薬研究へ.平成24年度前期(春期)有機合成化学講習会
- Place of Presentation
  東京
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2012
- Author(s)
  高山廣光
- Organizer
  有機合成2月セミナー「有機合成のニュートレンド2012」
- Place of Presentation
  大阪
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Fawcettimine型リコポジウムアルカロイドHuperzine-Qの不斉全合成2011
- Author(s)
  中山淳,小暮紀行,北島満里子,高山廣光
- Organizer
  第99回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2011
- Author(s)
  高山廣光
- Organizer
  理研シンポジウム第6回有機合成化学のフロンティア
- Place of Presentation
  和光
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Synthetic Study of Lycoposerramine-R, A Novel Skeletal Type of Lycopodium Alkaloids2011
- Author(s)
  S. Kimura, N. Kogure, M. Kitajima, and H. Takayama
- Organizer
  8th AFMC International Medicinal Chemistry Symposium (AIMECS11)
- Place of Presentation
  Tokyo
- Year and Date
  2011-12-30
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2011
- Author(s)
  高山廣光
- Organizer
  第6回有機合成化学のフロンティア
- Place of Presentation
  和光(招待講演)
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Synthetic Studies of Fawcettimine-type Lycopodium Alkaloids, Potential Seed Molecules for Drug Development2011
- Author(s)
  A. Nakayama, N. Kogure, M. Kitajima,and H. Takayama
- Organizer
  8th AFMC International Medicinal Chemistry Symposium (AIMECS11)
- Place of Presentation
  Tokyo
- Year and Date
  2011-12-30
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] ヒカゲノカズラ科植物2種より単離した新規アルカロイド類の構造2010
- Author(s)
  片川和明, 小暮紀行, 北島満里子, 本澤勝年, 有澤宗久, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] リコポジウム属植物トウゲシバ含有アルカロイドの探索と化学.2010
- Author(s)
  高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] オピオイド性鎮痛アルカロイド mitragynine の構造活性相関研究2010
- Author(s)
  小柳美寿々, 中山輝美, 三澤香織, 小暮紀行, 北島満里子, 松本健次郎, 堀江俊治, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] リコポジウム属植物トウゲシバ含有アルカロイドの探索と化学2010
- Author(s)
  高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Pauson-Khand反応を基盤としたfawcettimine型リコポジウムアルカロイド類の不斉全合成研究2010
- Author(s)
  中山淳,小暮紀行,北島満里子,高山廣光
- Organizer
  第36回反応と合成の進歩シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Lycoposerramine-Cおよび-Sの不斉全合成研究2010
- Author(s)
  中山淳, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 不斉 Claisen 転位を鍵段階とした三量体型インドールアルカロイド Psychotrimine の不斉全合成2010
- Author(s)
  高橋伸明, 伊藤健, 松田洋平, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 中国雲南省産 Kopsia arborea 含有新規アルカロイド成分の探索研究2010
- Author(s)
  佐々木みゆき, 〓〓秋, 北島満里子, 小暮紀行, 張栄平, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Investigation and Syntheses of Novel Analgesic Indole Alkaloids in Rubiaceous Medicinal Plants.2010
- Author(s)
  H.Takayama
- Organizer
  The 1^<st> Joint Symposium on Pharmaceutical Sciences between College of Pharmacy, Seoul National University and Graduate School of Pharmaceutical Sciences, Chiba University
- Place of Presentation
  千葉
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Investigation and Syntheses of Novel Analgesic Indole Alkaloids in Rubiaceous Medicinal Plants2010
- Author(s)
  H. Takayama
- Organizer
  The 1^<st> Joint Symposium on Pharmaceutical Sciences between College of Pharmacy, Seoul National University and Graduate School ofPharmaceutical Sciences, Chiba University - Cutting-Edge Research on Natural Products -
- Place of Presentation
  Chiba
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] シロイヌナズナにおける二つのMYB遺伝子同時過剰発現による遺伝子発現及びフラボノイド蓄積への効果2009
- Author(s)
  中林亮,榊原圭子,松田史生,峠隆之,北島満里子,高山廣光,山崎真巳,斉藤和季
- Organizer
  第4回メタボロームシンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] Lycopodium serratum 由来新規 Lycopodium アルカロイド類の不斉全合成2009
- Author(s)
  中山淳, 田中智之, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第51回天然有機化合物討論会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-07
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 新規 Kopsia アルカロイド Kopsiyunnanine Eの不斉全合成研究2009
- Author(s)
  高橋伸明, 〓〓秋, 北島満里子, 高山廣光
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 抗腫瘍性新規三量体型インドールアルカロイド Psychotrimine の不斉全合成2009
- Author(s)
  高橋伸明, 伊藤健, 松田洋平, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] タイ産 Lycopodiumu squarrosam 含有アルカロイドの成分探索2009
- Author(s)
  見藤裕子, 北島満里子, 小暮紀行, 高山廣光
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 新規リコポジウムアルカロイド Lycoposerramine Cの不斉全合成研究2009
- Author(s)
  中山淳, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 化学研究デザイン塾創薬をリードする新しい機能性天然分子の発見と創薬を目指して2009
- Author(s)
  高山廣光
- Organizer
  第26回和漢薬医薬学会
- Place of Presentation
  千葉
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 化学研究デザイン塾創薬をリードする新しい機能性天然分子発見と創薬を目指して.2009
- Author(s)
  高山廣光
- Organizer
  第26回和漢薬医薬学会学術大会
- Place of Presentation
  千葉
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Cernuine および関連リコポジウムアルカロイド類の全合成2008
- Author(s)
  西川泰弘, 北島満里子, 高山廣光
- Organizer
  第93回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 中国雲南省産 Kopsia officinalis より新規アルカロイドの探索2008
- Author(s)
  〓〓秋, 小暮紀行, 北島満里子, 張栄平, 高山廣光
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 新規四量体型インドールアルカロイド psychotetramine の全合成研究2008
- Author(s)
  松田洋平, 北島満里子, 高山廣光
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Flavonoid profiling and transcriptome in Arabidopsis overexpressing two MYB genes.2008
- Author(s)
  R.Nakabayashi, K.Yonekura-Sakakibara, F.Matsuda, T.Tohge, M.Kitajima, H.Takayama, M.Yamazaki, K.Saito
- Organizer
  5^<th> International Conference on Plant Metabolomics.
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] オピオイド性鎮痛アルカロイド、mitragynine を基盤とした構造活性相関研究2008
- Author(s)
  中山輝美, 松本健次郎, 北島満里子, 堀江俊治, 高山廣光
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 二つのMYB遺伝子の同時過剰発現体におけるトランスクリプトームとフラボノイドプロファイル2008
- Author(s)
  中林亮,榊原圭子,松田史生,北島満里子,高山廣光,山崎真巳,斉藤和季
- Organizer
  第26回日本植物細胞分子生物学会大阪大会・シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] Flavonoid profiling and transcriptome in Arabidopsis overexpressing two MYB genes2008
- Author(s)
  R.Nakabayashi, K.Yonekura-Sakakibara, F.Matsuda, T.Tohge, M.Kitajima, H.Takayama, M.Yamazaki, K.Saito
- Organizer
  5^<th> International Conference on Plant Metabolomics
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] 新規リコポジウムアルカロイド Lycoposerramine-XおよびZの不斉全合成研究2008
- Author(s)
  田中智之, 重山貴秀, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第27回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-11-26
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Quinolizidine 型リコポジウムアルカロイド類の全合成研究2008
- Author(s)
  西川泰弘, 北島満里子, 高山廣光
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Novel Indole Alkaloids, Kopsiyunnanines A～D from Kopsia officinalis2008
- Author(s)
  〓〓秋, 末弘真有, 高橋伸明, 小暮紀行, 北島満里子, 高山廣光, 張栄平
- Organizer
  第50回天然有機化合物討論会
- Place of Presentation
  福岡
- Year and Date
  2008-09-30
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Quinolizidine 型リコポジウムアルカロイド類のダイバージェント合成研究2007
- Author(s)
  西川泰弘, 北島満里子, 高山廣光
- Organizer
  第33回反応と合成の進歩シンポジウム
- Place of Presentation
  長崎
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 三環性複素環とポリアミンのハイブリッド型構造を有する新規NMDA受容体阻害剤の創製研究2007
- Author(s)
  八重樫優一, 北島満里子, 韓霞, 西村和洋, 奥山茂, 五十嵐一衛, 高山廣光
- Organizer
  第26回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 新規三量体型インドールアルカロイド psychotrimine の全合成2007
- Author(s)
  松田洋平, 森郁江, 北島満里子, 高山廣光
- Organizer
  第49回天然有機化合物討論会
- Place of Presentation
  札幌
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Investigation and Synthesis of Novel Analgesic Indole Alkaloids in Rubiaceous Medicinal Plants.2007
- Author(s)
  H. Takayama
- Organizer
  The JSPS 2nd Medicinal Chemistry Seminor of Asia/Africa Science Olatform Program
- Place of Presentation
  Phuket (Thailand)
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-18032019
[Presentation] 新規 Phlegmarine 型リコポジウムアルカロイド Lycoposerramine-VおよびWの不斉全合成2007
- Author(s)
  重山貴秀, 片川和明, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第92回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 新規KopsiaアルカロイドKopsiyunnanune Eの不斉全合成研究
- Author(s)
  村上洋介, 高橋伸明, 呉煜秋, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 腫瘍細胞選択性を指向したコルヒチン系ダブルプロドラッグ化合物の合成研究
- Author(s)
  遠藤慎平, 八十歩直子, 北島満里子, 小暮紀行, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] オピオイド性鎮痛インドールアルカロイドMitragynine誘導体の医薬化学的研究
- Author(s)
  片山健, 井上峻, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規iboga型インドールアルカロイドの不斉全合成研究
- Author(s)
  浅場絢ヌネッツ, 原田真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] ミソハギ科植物含有新規ビフェニルキノリチジンアルカロイド類の全合成研究
- Author(s)
  梅村隆之, 瓦井克孝, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Voacanga africana含有生物活性新規インドールアルカロイドの探索と不斉全合成研究
- Author(s)
  浅場絢ヌネッツ, 原田真也, 岩井真澄, Mee Wah Lo, 小暮紀行, 北島満里子, 花尻（木倉）瑠理, 合田幸広, 高山廣光
- Organizer
  第55回天然有機化合物討論会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] シロイヌナズナ花粉特異的フラボノールの高次配糖化酵素遺伝子の機能同定とその局在性
- Author(s)
  榊原圭子, 中林亮, 菅原聡子, 峠隆之, 伊藤卓也, 小柳美寿々, 北島満里子, 高山廣光, 斉藤和季
- Organizer
  第55回植物生理学会年会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規骨格LycopodiumアルカロイドLycoposerramine-Rの不斉全合成研究
- Author(s)
  石田寛明, 木村真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] LycopodiumアルカロイドLycodineの生合成経路を模擬した短段階不斉全合成
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 金触媒環化反応を用いたAkuammiline型インドールアルカロイドの全合成研究
- Author(s)
  高梨憲幸, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第48回天然物化学談話会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] LycopodiumアルカロイドLycodineの生合成経路を模擬した短段階不斉全合成
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第39回反応と合成の進歩シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] KopsiaアルカロイドAndranginineの全合成研究
- Author(s)
  三森雄二, 玉田卓矢, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] LycopodiumアルカロイドLycodineの生合成経路を模擬した不斉全合成研究
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第48回天然物化学談話会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Lycoposerramine-Rの不斉全合成研究
- Author(s)
  石田寛明, 木村真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第48回天然物化学談話会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Voacanga africana由来アルカロイドVoacangineのThrmo-TRPsへの作用
- Author(s)
  寺田祐子, 堀江俊治, 高山廣光, 渡辺達夫
- Organizer
  第28回日本香辛料研究会学術講演会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Lycopodium nummularifolium含有のアルカロイドの探索研究
- Author(s)
  岡部慧, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Akuammiline型インドールアルカロイドGomalineの全合成研究
- Author(s)
  高梨憲幸, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] フキ (Petasites japonicus) に含有されるピロリジジンアルカロイド類の検索研究
- Author(s)
  岡部慧, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第5回食品薬学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 金触媒環化反応を用いたSarpagine型インドールアルカロイドの全合成研究
- Author(s)
  前田博行, 鈴木健太, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKAM1の不斉全合成研究
- Author(s)
  德田涼子, 高橋伸明, 佐々木みゆき, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規Colchicine誘導体の合成を抗腫瘍効果
- Author(s)
  西山裕之, 小野雅弘, 杉本卓弥, 笹井俊雄, 浅川直之, 上野哲, 富永恵隆, 八重樫隆, 長岡正人, 松崎健, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] キョウチクトウ科Kopsia arborea含有インドールアルカロイドの構造解析
- Author(s)
  北島満里子, 小山徹也, Yuqui Wu, 小暮紀行, Rongping Zhang, 高山廣光
- Organizer
  日本生薬学会第60回年会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-25293023

1. KITAJIMA Mariko (60195261)

# of Collaborated Projects: 11 results

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2. AIMI Norio (30009170)

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3. HORIE Shunji (50209285)

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4. SAKAI Shin-ichiro (20009161)

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5. KOGURE Noriyuki (80396689)

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6. SAITO Kazuki (00146705)

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7. YAMAZAKI Mami (70222370)

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8. NOJI Masaaki (80271534)

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9. YANO Shingo (90009655)

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11. KANAYA Shigehiko (90224584)

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14. ARITA Masanori (10356389)

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15. 五十嵐一衛 (60089597)

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16. STOCKIGT Joachim

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17. PONGLUX D.

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18. STOCKIGT J.

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19. DHAVADEE Pon

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20. YOSHIMOTO Naoko (10415333)

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21. KUSANO MIYAKO (60415148)

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22. NAKABAYASHI Ryo (30586160)

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23. AOKI Toshio (80287606)

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24. WATANABE Hiroshi (10012642)

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25. KUBO Akinori (60097201)

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26. SAITO Naoki (80142545)

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27. MURAYAMA Toshihiko (90174317)

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28. NAKAMURA Tomonori (30251151)

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29. KOIZUMI Toru (40012611)

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30. ARAI Yoshitsugu (10115157)

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31. TAKEUCHI Yoshio (20111750)

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36. 宮瀬敏男 (60112497)

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40. 谷時雄 (80197516)

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41. OBITZ Peter

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42. TONGROCH Pavich

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44. STOECKIGT Joachim

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48. JOACHIM Stoe

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49. PANG Peter K

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50. KTPANG Peter

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51. JOACHIM Stoc

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52. PAVICH Tongr

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53. JOACHIM Sto

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58. TERUI Yusuke

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63. 成田年

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TAKAYAMA Hiromitsu 高山 廣光

TAKAYAMA Hiromitu 高山 広光

高山 広光 タカヤマ ヒロミツ

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Studies on development of novel asymmetric organocatalysts and oligonucleotide-recognition probes based on natural alkaloidPrincipal Investigator

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Studies on search and synthesis of plant alkaloids for the development of new medicines for pain and improving the memory disordersPrincipal Investigator

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Studies on the synthesis of SPECT probe to elucidate the in vivo dynamics of natural opioidsPrincipal Investigator

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Search for natural molecules that control memory and pain from medicinal resources and drug development reserachPrincipal Investigator

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Studies on isolation, total synthesis and medicinal chemistryof natural products with regulating activities on memory and pain.Principal Investigator

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新規NMDA受容体チャネルブロッカー探索による脳機能改善薬の創製Principal Investigator

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Search, asymmetric synthesis, and medicinal chemistry study on the plant alkaloids that regulate the brain nervous system.Principal Investigator

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オピオイド受容体サブタイプを分子標的とする機能性コリナンテ型アルカロイドの開発Principal Investigator

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モルヒネを超える新規オピオイド性鎮痛アルカロイドの探索と創製Principal Investigator

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TAKAYAMA Hiromitsu 高山廣光

TAKAYAMA Hiromitu 高山広光

高山広光タカヤマヒロミツ