TAKAYAMA Hiromitsu 高山廣光

Researcher Number	90171561
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Affiliation *help	2016 – 2017 : 千葉大学, 大学院薬学研究院, 教授 2010 – 2016 : Chiba University, 薬学研究科(研究院), 教授 2007 – 2012 : Chiba University, Graduate School of Pharmaceutical Sciences, Professor 2005 – 2009 : 千葉大, 薬学研究科(研究院), 教授 2005 – 2007 : 千葉大学, 大学院薬学研究院, 教授 … More
Review Section/Research Field	Principal Investigator Natural medicines / Drug development chemistry / Science and Engineering / Bioorganic chemistry / Chemical pharmacy / Living organism molecular science / 医薬分子機能学 / Pharmaceutical Sciences and related fields Except Principal Investigator Chemical pharmacy / Living organism molecular science / Synthetic chemistry / Applied genomics
Keywords	Principal Investigator 構造活性相関 / アルカロイド / オピオイド / インドールアルカロイド / 全合成 / 脳機能改善薬 / Mitragyna speciosa / 天然物化学 / 生物活性物質の探索 / 天然活性物質 … More Except Principal Investigator アルカロイド / Gelsemium elegans / Gelsemium sempervirens / 抗腫瘍活性 / フラボノイド / Rubiaceae / 全合成 / antitumor activity / 毛状根 / メタボロミクス / alkaloid / イリドイド / Indole Alkaloids / シロイヌナズナ / バイオインスパイアード反応 / トランスクリプトミクス / アカネ科 / Loganiaceae / ゲノム機能科学 / インドールアルカロイド / アントシアニン / Raumaclines / Rauwolfia serpentina / オピオイド受容体 / 生合成 / 構造決定 / EC_<50> / インド-ルアルカロイド / indole alkaloid / 化学変換 / Aspidosperma quebracho blanco / camptothecin / 二次代謝 / マチン科 / メタボローム / Mitragyna speciosa / Ophiorrhiza pumila / システイン / 再生植物 / Apocynaceae / hairy roots / Raumacline / 細胞毒性 / Asymmetric Diels-Alder Reaction / Camphothecin / モデル植物 / Aspidochibine / 二次代謝産物 / GST / 機能ゲノミクス / テルペン / <alpha> , <beta> -Unsaturated Sulfoxides / 植物成分 / 融合細胞 / 脱顆粒抑制作用 / Thai medicinal plant / 不斉環化付加 / serotonin receptor / Gelsemium sempervilens / marine natural product / 鎮痛活性 / トランスクリプトム / Indole alkaloid / オピオイド / phylogenelic analyses of DNA / Biomimetic Synthesis / 生物変換 / イロドイド / prolyl endopeptidase / Aspidochibine. / Aspidasperma queblacho blanco / インドール / タイ薬用植物 / Arabidopsis thaliana / イソキノリン / Plant Tissue Cultures / 細胞融合 / opioid / 二量化反応 / 水中反応 / DNAマイクロアレイ / Ca channel / Ophiorrhiza pimila / DNAによる系統解析 / RNAi / 植物細胞培養 / callus / 実用植物 / マナン科 / Secondary metabolism / total synthesis / Ophiorrhiza spp. / 薬用植物 / metabolomics / 転位反応 / 系統解析 / トランスクリプトー / Caチャンネル / α,β-不飽和スルホキシド / ジケトピペラジン / biosynthesis / isoquinoline / 毒性 / opioid agonist / Cell fusion / structure elucidation / anti-HSV-1 / 海洋天然物 / プレニル化反応 / 代謝 / Differentiation / アルカロイド化学合成 / toxicity / 生産制御 / 9-β-D-Glucosyloxycamptothecin / Biotransformation of ajmaline / antioxidant / アントラキノン / 一電子酸化 / transcriptomics / chiral synthesis / gelsedine / deoxypumiloside / 高ジアステレオ選択性 / Malaysian medicinal plant / Gelsemium / functional genomics / Aspidosperma gmbir / キョウチクトウ科 / カンプトテシン / キノリチジンアルカロイド / ミトラガイニン / metabolism / secondary metabolism / 生合成模擬反応 / Deoxypumilosides / anthocyanin / セロトニン受容体 / 腫瘍細胞殺傷活性 / メタボロム / cytotoxic / 物質生産 / グルコシノレート / 多変量解析 / comparative genetics / 再分化 / Mitragyna spociosa / ワンポット反応 / Rauwolfia sumatorana / アジマリン / Rauwolfia serpentina Benth / Hunteria zeylanica / opioid receptor / pumiloside / アゼチジン環 / キラル合成 / 平滑筋収縮作用 / Rhazya stricta / Anthraquinone / 植物組織培養 / regenerated plants / Structure Elucidation / 不斉ディールス・アルダー反応 / analgesic effect / 集団的合成 / アルカロイドの化学合成 / Mitragynine / 化学合成 / カルス / Plant cell culture / indole / ゲノム機能学 / ミトラガイナスペシオーサ / 自己組織化マップ / mitragynine / 栄養ストレス / 組織培養 / Asymmetric Cycloaddition / cytotoxicity / ゲルセミウム / Camptothecin / 2-アシルインドール / 化学変換反応 / Deoxypumilosid / quinolizidine alkaloid / オピオイド作用 / 生合成的化学合成 / 急性毒性 / Gelsedine Less

Collective synthesis of monoterpenoid indole alkaloid using bioinspired reactionsOngoing
- Principal Investigator
  
  石川勇人
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Kumamoto University
アルカロイド由来の新規有機不斉触媒と特定配列オリゴヌクレオチド認識分子の創製Principal InvestigatorOngoing
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Chiba University
植物アルカロイドの探索と合成研究を基盤とした、疼痛および脳機能改善薬の創成Principal InvestigatorOngoing
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Chiba University
Studies on the synthesis of SPECT probe to elucidate the in vivo dynamics of natural opioidsPrincipal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Natural medicines
- Research Institution
  Chiba University
Synthetic study of biologically active alkaloids using bio-inspired reactions
- Principal Investigator
  
  ISHIKAWA HAYATO
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Kumamoto University
Search for natural molecules that control memory and pain from medicinal resources and drug development reserachPrincipal Investigator
- Principal Investigator
  
  TAKAYAMA HIROMITSU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Chiba University
Studies on isolation, total synthesis and medicinal chemistryof natural products with regulating activities on memory and pain.Principal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Chiba University
新規NMDA受容体チャネルブロッカー探索による脳機能改善薬の創製Principal Investigator
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Chiba University
Phytochemical genomics : Genomic basis for phytochemical diversity
- Principal Investigator
  
  SAITO Kazuki
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Chiba University
Search, asymmetric synthesis, and medicinal chemistry study on the plant alkaloids that regulate the brain nervous system.Principal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Chiba University
オピオイド受容体サブタイプを分子標的とする機能性コリナンテ型アルカロイドの開発Principal Investigator
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Chiba University
モルヒネを超える新規オピオイド性鎮痛アルカロイドの探索と創製Principal Investigator
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Chiba University
Comparative genomics of model plant and non-model plants based on metabolome analysis
- Principal Investigator
  
  YAMAZAKI Mami
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Chiba University
Studies on the Gelsemium Alkaloids for the Discovery and Development of New Antitumor Natural Products.
- Principal Investigator
  
  KITAJIMA Mariko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Chiba University
Metabolomics-based post-genome science in plants
- Principal Investigator
  
  SAITO Kazuki
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Chiba University
益々重要性が認識されつつある天然医薬資源の健康科学への拡大応用に関する調査研究
- Principal Investigator
  
  野原稔弘
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kumamoto University
Development of New Type of Potent Opioid Agonists and the Molecular Mechanism for Exhibiting their Analgesic ActivityPrincipal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Study on the Alkaloid Production of Two Gelsemium Plants by Using their Callus Cultures and Chemical and Pharmacological Investigation of Gelsemium Alkaloids.
- Principal Investigator
  
  KITAJIMA Mariko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  CHIBA UNIVERSITY
熱帯雨林地域の資源植物を利用した創薬シード分子の検索と化学的研究Principal Investigator
- Principal Investigator
  
  高山廣光
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Medicinal Chemistry on Alkaloids from Plants in Malaya Area
- Principal Investigator
  
  KUBO Akinori
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Chemical pharmacy
- Research Institution
  MEIJI PHARMACEUTICAL UNIVERSITY
Studies on the development of new opioid agonist by utilizing Mitragyna alkaloids as the lead-compoundsPrincipal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  医薬分子機能学
- Research Institution
  Chiba University
Chemical and Biological Studies on Production of Camptothecin-related Molecules by Use of the Domestic Medicinal Resource Plant
- Principal Investigator
  
  AIMI Norio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Chemical Study of Alkaloids in Tropical Medicinal Plants as the Lead-Compounds to Develop New Biologically Functional Molecules.Principal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Chiba University
Medicinal Chemistry on Indole Alkaloids from Thai Medicinal Plants
- Principal Investigator
  
  SAKAI Shin-ichiro
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Investigation and synthetic studies of bioactive Mitragyna alkaloids.Principal Investigator
- Principal Investigator
  
  TAKAYAMA Hiromitsu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Chiba University
Formation of Alkaloid's by Function of Cultured Plant Cells
- Principal Investigator
  
  AIMI Norio
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Chemical Study on the Indole Alkaloids from Plant Tissue Cultures
- Principal Investigator
  
  SAKAI Shin-ichiro
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Synthetic Studies on the Gelsemium Alkaloids Based on the Biogenetic Speculation
- Principal Investigator
  
  SAKAI Shin-ichiro
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Studies on A Novel Asymmetric Cycloaddition Using Optically Active <alpha> , <beta> -Unsaturated Sulfoxides
- Principal Investigator
  
  KOIZUMI Toru
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toyama Medical & Pharmaceutical University

[Book] The Alkaloids: Chemistry and Biology (Chapter 4: Monoterpenoid Bisindole Alkaloids)2016
- Author(s)
  M. Kitajima, H. Takayama
- Total Pages
  340
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-25293023
[Book] Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source (Chapter 9: Medicinal Chemistry Based on Mitragynine)2015
- Author(s)
  H. Takayama, M. Kitajima
- Total Pages
  366
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-26670042
[Book] Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source (Chapter 8: Chemistry of Mitragyna Alkaloids)2015
- Author(s)
  M. Kitajima, H. Takayama
- Total Pages
  366
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-26670042
[Book] Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source (Chapter 8: Chemistry of Mitragyna Alkaloids)2015
- Author(s)
  Mariko Kitajima and Hiromitsu Takayama
- Total Pages
  366
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-25293023
[Book] Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source (Chapter 9: Medicinal Chemistry Based on Mitragynine)2015
- Author(s)
  Hiromitsu Takayama and Mariko Kitajima
- Total Pages
  366
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-25293023
[Book] パートナー天然物化学2012
- Author(s)
  高山廣光
- Total Pages
  24
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22390019
[Book] Lycopodium Alkaloids: Isolation and Asymmetric Synthesis. Topics in Current Chemistry, "Alkaloid Synthesis"2012
- Author(s)
  Mariko Kitajima and Hiromitsu Takayama
- Publisher
  ed. by H.-J. Knolker, Springer
- Data Source
  KAKENHI-PROJECT-22390019
[Book] Topics in Current Chemistry, "Alkaloid Synthesis"2011
- Author(s)
  M.Kitajima, H.Takayama
- Total Pages
  32
- Publisher
  Lycopodium Alkaloids : Isolation and Asymmetric Synthesis
- Data Source
  KAKENHI-PROJECT-22390019
[Book] パートナー天然物化学(第5章)2007
- Author(s)
  高山廣光(共著)
- Total Pages
  25
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-19310137
[Book] 天然物化学 -植物編-2007
- Author(s)
  高山廣光(共著)
- Total Pages
  10
- Publisher
  アイピーシー
- Data Source
  KAKENHI-PROJECT-18032019
[Book] 天然物化学 -植物編-2006
- Author(s)
  高山廣光 (分担執筆)
- Total Pages
  10
- Publisher
  アイピーシー
- Data Source
  KAKENHI-PROJECT-18032019
[Journal Article] Synthetic Study of Biphenylquinolizidine Alkaloids I. Asymmetric Total Synthesis of Lasubine I Featuring Organocatalyzed Asymmetric Intramolecular aza-Michael Addition2017
- Author(s)
  T. Hirama, T. Umemura, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Tetrahedron Lett.
  
  Volume : 58 Pages : 223-226
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-26293023
[Journal Article] Design and Synthesis of 4-Chlorocolchicine-Derived Prodrug Capable of Forming Nanoparticles by Self-assembly. Heterocycles2017
- Author(s)
  M. Kitajima, A. Morita, S. Endo, N. Kogure, K. Higashi, K. Moribe, H. Takayama
- Journal Title
  
  Heterocycles
  
  Volume : 95 Pages : 181-186
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-26293023
[Journal Article] Identification of Novel Glutathione Adducts of Benzbromarone in Human Liver Microsomes2017
- Author(s)
  N. Cho, K. Kobayashi, M. Yoshida, N. Kogure, H. Takayama, K. Chiba
- Journal Title
  
  Drug. Metab. Pharmacokinet.
  
  Volume : 32 Pages : 46-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05094
[Journal Article] New Lycopodine-type Alkaloids from Lycopodium carinatum2016
- Author(s)
  N. Kogure, M. Maruyama, S. Wongseripipatana, M. Kitajima, H. Takayama
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume : 64 Pages : 0-0
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Asymmetric Total Synthesis of Sarpagine-Related Indole Alkaloids, Hydroxygardnerine, Hydroxygardnutine, Gardnerine, (E)16-epi-Normacusine B, and Koumine2016
- Author(s)
  M. Kitajima, K. Watanabe, H. Maeda, N. Kogure, H. Takayama
- Journal Title
  
  Org. Lett.
  
  Volume : 18 Pages : 1912-1915
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023, KAKENHI-PROJECT-16H05094
[Journal Article] Total Synthesis of Conolidine and Apparicine2016
- Author(s)
  N. Takanashi, K. Suzuki, M. Kitajima, H. Takayama
- Journal Title
  
  Tetrahedron Lett.
  
  Volume : 57 Pages : 375-378
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023
[Journal Article] New Lycopodine-type Alkaloids from Lycopodium carinatum2016
- Author(s)
  N. Kogure, M. Maruyama, S. Wongseripipatana, M. Kitajima, H. Takayama
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume : 64 Pages : 793-799
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094
[Journal Article] Asymmetric Total Synthesis of Kopsiyunnanine K, a Monoterpenoid Indole Alkaloid with a Rearranged Skeleton2016
- Author(s)
  R. Tokuda, Y. Okamoto, T. Koyama, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Org. Lett.
  
  Volume : 18 Pages : 3490-3493
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-26293023
[Journal Article] Kopsiyunnanines L and M, Strychnos-related Monoterpenoid Indole Alkaloids from Yunnan Kopsia arborea2016
- Author(s)
  M. Kitajima, M. Nakazawa, Y. Wu, N. Kogure, R. Zhang, H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume : 72 Pages : 6692-6696
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094, KAKENHI-PROJECT-26293023
[Journal Article] Characterization of a Recently Evolved Flavonol-Phenylacyltransferase Gene Provides Signatures of Natural Light Selection in Brassicaceae2016
- Author(s)
  T. Tohge, R. Wendenburg, H. Ishihara, R. Nakabayashi, M.Watanabe, R. Sulpice, R. Hoefgen, H. Takayama, K. Saito M. Stitt, A. R. Fernie
- Journal Title
  
  Nature Communications
  
  Volume : 7 Pages : 12399-12399
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05094
[Journal Article] Kopsiyunnanines J1 and J2, New Strychnos-type Homo-Monoterpenoid Indole Alkaloids from Kopsia arborea2015
- Author(s)
  M. Kitajima, T. Koyama, Y. Wu, N. Kogure, R. Zhang, and H. Takayama
- Journal Title
  
  Nat. Prod. Commun.
  
  Volume : 10 Pages : 49-51
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Total Synthesis of (±)-Lycoposerramine-R, a Novel Skeletal Type of Lycopodium Alkaloid2015
- Author(s)
  H. Ishida, S. Kimura, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume : 71 Pages : 51-56
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-25460005, KAKENHI-PROJECT-26293023
[Journal Article] The Cellular Toxicology of Mitragynine, the Dominant Alkaloid of the Narcotic-like Herb, Mitragyna speciosa Korth.2015
- Author(s)
  N. A. Saidin, E. Holmes, H. Takayama, N. J. Gooderham
- Journal Title
  
  Toxicol. Res.
  
  Volume : 4 Pages : 1173-1183
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Recent Progress in Total Synthesis of Lycopodium Alkaloids2015
- Author(s)
  H. Takayama
- Journal Title
  
  J. Synth. Org. Chem. Jpn.
  
  Volume : 73 Pages : 1062-1071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] The First Asymmetric Total Synthesis of Lycoposerramine-R2015
- Author(s)
  H. Ishida, S. Kimura, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume : 13 Pages : 7762-7771
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023
[Journal Article] Boosting Sensitivity in Liquid Chromatography-Fourier Transform Ion Cyclotron Resonance-Tandem Mass Spectrometry for Product Ion Analysis of Monoterpene Indole Alkaloids2015
- Author(s)
  R. Nakabayashi, H. Tsugawa, M. Kitajima, H. Takayama, K. Saito
- Journal Title
  
  Front. Plant. Sci.
  
  Volume : 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023
[Journal Article] Iridoids and a Norsesquiterpenoid from the Leaves of Villaria odorata2014
- Author(s)
  M. A. Tan, R. A. U. Villacorta, G. J. D. Alejandro, and H. Takayama
- Journal Title
  
  Nat. Prod. Commun.
  
  Volume : 9 Pages : 1229-1230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Chemical Constituents from Psychotria cadigensis and their chemotaxonomic relevance2014
- Author(s)
  M. A. Tan, G. F. M. Panghulan, M. M. Uy, and H. Takayama
- Journal Title
  
  Am. J. Ess. Oils Nat. Prod.
  
  Volume : 1 Pages : 18-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Biogenetically Inspired Total Syntheses of Lycopodium Alkaloids, (+)-Flabellidine and (–)-Lycodine2014
- Author(s)
  M. Azuma, T. Yoshikawa, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume : 136 Pages : 11618-11621
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-25460005, KAKENHI-PROJECT-26293023
[Journal Article] Asymmetric Total Synthesis of Novel Pentacyclic Indole Alkaloid, Kopsiyunnanine E, Isolated from Kopsia arborea2014
- Author(s)
  M. Kitajima, Y. Murakami, N. Takahashi, Y. Wu, N. Kogure, R. Zhang, and H. Takayama
- Journal Title
  
  Org. Lett.
  
  Volume : 16 Pages : 5000-5003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023
[Journal Article] Identification of indole alkaloid structural units important for stimulus selective TRPM8 inhibition: SAR study of naturally occurring iboga derivatives.2014
- Author(s)
  7.Terada Y., Kitajima M., Taguchi F., Takayama H., Horie S., Watanabe T.
- Journal Title
  
  J. Nat. Prod.
  
  Volume : 77 Pages : 1831-1838
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24580194, KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293023, KAKENHI-PROJECT-12J10919
[Journal Article] Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree.2014
- Author(s)
  Terada Y., Horie S., Takayama H., Uchida K., Tominaga M., Watanabe, T.
- Journal Title
  
  J. Nat. Prod.
  
  Volume : 77 Pages : 285-297
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24580194, KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-25871061, KAKENHI-PROJECT-12J10919
[Journal Article] A New Sesquiterpenoid from Scaphium macropodum (Miq.) Beumee2014
- Author(s)
  L. M. Ramadhan Al Muqarrabun, Norizan Ahmat, S. Ruzaina S. Aris, Nurdiana Shamsulrijal, Syarul N. Baharum, Rafidah Ahmad, A. Rifki Rosandy, M. Nazip Suratman, and H. Takayama
- Journal Title
  
  Nat. Prod. Res.
  
  Volume : 28 Pages : 597-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] 4-Chlorocolchicine Derivatives Bearing a Thiourea Side Chain at the C-7 Position as Potent Anticancer Agents2014
- Author(s)
  H. Nishiyama, M. Ono, T. Sugimoto, T. Sasai, N. Asakawa, S. Ueno, Y. Tominaga, T. Yaegashi, M. Nagaoka, T. Matsuzaki, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Med. Chem. Commun.
  
  Volume : 5 Pages : 452-458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Orally active opioid μ/δ dual agonist MGM-16, a derivative of the indole alkaloid mitragynine, exhibits potent antiallodynic effect on neuropathic pain in mice.2014
- Author(s)
  Matsumoto K, Narita M, Muramatsu N, Nakayama T, Misawa K, Kitajima M, Tashima K, Devi LA, Suzuki T, Takayama H, Horie S.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume : 348 Pages : 383-392
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23590651, KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-25293023, KAKENHI-PROJECT-26293346, KAKENHI-PROJECT-26640015
[Journal Article] Chemotaxonomic relevance of the constituents from the leaves of Rothmannia merrillii2014
- Author(s)
  M. A. Tan, C. N. L. Concepcion1, Grecebio Jonathan D. Alejandro and H. Takayama
- Journal Title
  
  J. Chem. Pharm. Res.
  
  Volume : 6 Pages : 779-781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Indole alkaloids from Kopsia jasminiflora2014
- Author(s)
  M. Kitajima, M. Anbe, N. Kogure, S. Wongseripipatana, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume : 70 Pages : 9099-9106
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Aspidosperma-aspidosperma-type Bisindole Alkaloids from2013
- Author(s)
  M. Kitajima, M. Iwai, N. Kogure, R.Kikura-Hanajiri, Y. Goda, and H. Takayama
- Journal Title
  
  Voacanga africana. Tetrahedron
  
  Volume : 69(2) Pages : 796-801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] β-Carboline-type Indole Alkaloid Glycosides from Ophiorrhiza trichocarpon2013
- Author(s)
  M. Kitajima, S. Ohara, N. Kogure, D. Santiarworn, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume : 69 Pages : 9451-9456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293023
[Journal Article] Syntheses of Fawcettimine-type Lycopodium Alkaloids Utilizing Pauson-Khand Reaction2012
- Author(s)
  A. Nakayama, M. Kitajima, and H.Takayama
- Journal Title
  
  Synlett
  
  Volume : 23(14) Pages : 2014-2024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] Chemical Conversion of Strychnine into Kopsiyunnanine-I, a New Hexacyclic Indole Alkaloid from Yunnan Kopsia arborea2012
- Author(s)
  N. Kogure, Y. Suzuki, Y. Wu, M.Kitajima, R. Zhang, and H. Takayama
- Journal Title
  
  Tetrahedron Lett
  
  Volume : 53(48) Pages : 6523-6526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224, KAKENHI-PROJECT-23790124
[Journal Article] Synthesis and Biological Evaluation of 4-Chlorocolchicine Derivatives as Potent Anticancer Agents with Broad Effective Dosage Ranges2012
- Author(s)
  H. Nishiyama, M. Ono, T. Sugimoto, T.Sasai, N. Asakawa, T. Matsumoto, T. Yaegashi, M. Nagaoka, T. Matsuzaki, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Med. Chem. Comm
  
  Volume : 3(12) Pages : 1500-1504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224, KAKENHI-PROJECT-23790124
[Journal Article] Secondary Metabolites from Pandanus simplex2012
- Author(s)
  M. A. Tan, M. G. Nonato, M. Kitajima, N. Kogure, and H. Takayama
- Journal Title
  
  Biochem. Syst. Ecol
  
  Volume : 40 Pages : 4-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] New Indole Alkaloids from Melodinus henryi2012
- Author(s)
  M. Kitajima, S. Ohara, N. Kogure, Y.Wu, R. Zhang, and H. Takayama
- Journal Title
  
  Heterocycles
  
  Volume : 85(8) Pages : 1949-1959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Asymmetric Total Synthesis of an Iboga-Type Indole Alkaloid, Voacangalactone, Newly Isolated from Voacanga africana2012
- Author(s)
  M. Harada, K. Asaba, M. Iwai, N.Kogure, M. Kitajima, and H.Takayama
- Journal Title
  
  Org. Lett
  
  Volume : 14(22) Pages : 5800-5803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] Seven New Monoterpenoid Indole Alkaloids from Gelsemium elegans2011
- Author(s)
  Y. Yamada, M. Kitajima, N. Kogure, S.Wongseripipatana, and H. Takayama
- Journal Title
  
  Chem. Asian J.
  
  Volume : 6(1) Pages : 166-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] Inhibitory Effect of Iboga-type Indole Alkaloids on Capsaicin-induced Contraction in Isolated Mouse Rectum2011
- Author(s)
  M. Lo, K. Matsumoto, M. Iwai, K.Tashima, M. Kitajima, S. Horie, and H. Takayama
- Journal Title
  
  J. Nat. Med
  
  Volume : 65(1) Pages : 157-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Discovery of Indole Alkaloids with Cannabinoid CB1 Receptor Antagonistic Activity2011
- Author(s)
  M. Kitajima, M. Iwai, R.Kikura-Hanajiri, Y. Goda, M. Iida, H. Yabushita, and H. Takayama
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume : 21(7) Pages : 1962-1964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Total Synthesis Guided Structure Elucidation of (+)-Psychotetramine2011
- Author(s)
  K. Foo, T. Newhouse, I. Mori, H.Takayama, and P.l S. Baran
- Journal Title
  
  Angew. Chem., Int. Ed
  
  Volume : 50(12) Pages : 2716-2719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Two New Alkaloids from Crinum asiaticum var. sinicum2011
- Author(s)
  N. Kogure, N. Katsuta, M. Kitajima, and H. Takayama
- Journal Title
  
  Chem. Pharm. Bull
  
  Volume : 59(12) Pages : 1545-1548
- URL
  https://www.jstage.jst.go.jp/article/cpb/59/12/59_12_1545/_pdf.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Total Synthesis of Dubiusamine C, A Plausible Minor Alkaloid in Pandanus dubius2011
- Author(s)
  M. A. Tan, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Phillippine Sci. Lett
  
  Volume : 4(2) Pages : 98-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Ten New Fawcettimine-related Alkaloids from Three Species of Lycopodium2011
- Author(s)
  K. Katakawa, H. Mito, N. Kogure, M.Kitajima, S. Wongseripipatana, M. Arisawa, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume : 67(35) Pages : 6561-6567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-23790124
[Journal Article] Asymmetric Total Synthesis of a Pentacyclic Lycopodium Alkaloid, Huperzine-Q. Angew2011
- Author(s)
  A. Nakayama, N. Kogure, M. Kitajima, and H. Takayama
- Journal Title
  
  Chem., Int. Ed.
  
  Volume : 50(35) Pages : 8025-8028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-23790124
[Journal Article] Design, Synthesis,and Antitumor Activity of4-Halocolchicines and their Pro-drugs Activated by Cathepsin B2011
- Author(s)
  N. Yasobu, M. Kitajima, N. Kogure, Y.Shishido, T. Matsuzaki, M. Nagaoka, and H. Takayama
- Journal Title
  
  ACS Med. Chem. Lett
  
  Volume : 2(5) Pages : 348-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Metacolchicine, A New Colchicinoid from Sandersonia aurantiaca2011
- Author(s)
  M. Kitajima, A. Tanaka, N. Kogure, and H. Takayama
- Journal Title
  
  Heterocycles
  
  Volume : 83(8) Pages : 1903-1907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Two New Aspidosperma Indole Alkaloids from Yunnan Kopsia arborea2010
- Author(s)
  Y. Wu, M. Kitajima, N. Kogure, Y.Wang, R. Zhang, and H. Takayama
- Journal Title
  
  Chem. Pharm. Bull
  
  Volume : 58(7) Pages : 961-963
- URL
  https://www.jstage.jst.go.jp/article/cpb/58/7/58_7_961/_pdf.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] New Pyrrolidine Alkaloids from the Roots of Pandanus amaryllifolius2010
- Author(s)
  M. A. Tan, M. Kitajima, N. Kogure, M.G. Nonato, and H. Takayama
- Journal Title
  
  Tetrahedron Lett
  
  Volume : 51(31) Pages : 4143-4146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] New Oxindole andIndole Alkaloids from Gelsemium rankinii2010
- Author(s)
  M. Kitajima, H. Kobayashi, N. Kogure, and H. Takayama
- Journal Title
  
  Tetrahedron
  
  Volume : 66(32) Pages : 5987-5992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019, KAKENHI-PROJECT-22510224
[Journal Article] Isolation of Pandamarilactonine-H from the Roots of Pandanus amaryllifolius and Synthesis of epi-Pandamarilactonine-H2010
- Author(s)
  M. A. Tan, M. Kitajima, N. Kogure, M.G. Nonato, and H. Takayama
- Journal Title
  
  J. Nat. Prod
  
  Volume : 73(8) Pages : 1453-1455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] 生物活性リコポジウムアルカロイドの探索と不斉合成2010
- Author(s)
  高山廣光
- Journal Title
  
  有合化
  
  Volume : 68(5) Pages : 457-469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390019
[Journal Article] Determination of Absolute Configuration of Trimeric Indole Alkaloid, Psychotrimine, by First Asymmetric Total Synthesis2010
- Author(s)
  N. Takahashi, T. Ito, Y. Matsuda, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Chem.Commun. 46
  
  Pages : 2501-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Metabolomics-oriented isolation and structure elucidation of 37 compounds including two new anthocyanins from Arabidopsis thaliana.2009
- Author(s)
  Ryo Nakabayashi, Miyako Kusano, Makoto Kobayashi, Takayuki Tohge, Keiko Yonekura-Sakakibara, Noriyuki Kogure, Mami Yamazaki, Mariko Kitajima, Kazuki Saito, Hiromitsu Takayama
- Journal Title
  
  Phytochemistry 70
  
  Pages : 1017-1029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] Metabolomics-oriented isolation and structure elucidation of 37 compounds including two new anthocyanins from Arabidopsis thaliana.2009
- Author(s)
  Ryo Nakabayashi, Miyako Kusano, Makoto Kobayashi, Takayuki Tohge, Keiko Yonekura-Sakakibara, Noriyuki Kogure, Mami Yamazaki, Mariko Kitajima, Kazuki Saito, Hiromitsu Takayama
- Journal Title
  
  Phytochemistry
  
  Volume : 70 Pages : 1017-1029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] Metabolomics-oriented isolation and structure elucidation of 37 compounds including two new anthocyanins from Arabidopsis thaliana2009
- Author(s)
  Ryo Nakabayashi, Miyako Kusano, Makoto Kobayashi, Takayuki Tohge, Keiko Yonekura-Sakakibara, Noriyuki Kogure, Mami Yamazaki, Mariko Kitajima, Kazuki Saito, Hiromitsu Takayama
- Journal Title
  
  Phytochemistry 70
  
  Pages : 1017-1029
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] Kopsiyunnanines F and Isocondylocarpines : New Tubotaiwine-type Alkaloids from Yunnan Kopsia arborea2009
- Author(s)
  Y. Wu, M. Kitajima, N. Kogure, Y. Wang, R. Zhang, H. Takayama
- Journal Title
  
  J.Nat.Med. 63
  
  Pages : 283-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] A Divergent Approach for the Total Syntheses of Cernuanetype and Quinolizidine-type Lycopodium Alkaloids2009
- Author(s)
  Y. Nishikawa, M. Kitajima, N. Kogure, H. Takayama
- Journal Title
  
  Tetrahedron 65
  
  Pages : 1608-1617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] A New Lycopodium Alkaloid, Lycoposerramine-R, with a Novel Sleleton and Three New Fawcettimie-Relted Alkaloids from Lycopodium serratum2009
- Author(s)
  K. Katakawa, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Helv.Chim.Acta 92
  
  Pages : 445-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Asymmetric Total Syntheses of Cyclic-Nitrone-Containing Phlegmarine-Type Lycopodium Alkaloids, Lycoposerramines-X and-Z2009
- Author(s)
  T. Tanaka, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  J.Org.Chem. 74
  
  Pages : 8675-8680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Rhazinilam and Quebrachamine Derivatives from Yunnan Kopsia arborea2009
- Author(s)
  Y. Wu, M. Suehiro, M. Kitajima, T. Matsuzaki, S. Hashimoto, M. Nagaoka, Masato, R. Zhang, H. Takayama
- Journal Title
  
  J.Nat.Prod. 72
  
  Pages : 204-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] First Asymmetric Total Syntheses of Fawcettimine-Type Lycopodium Alkaloids, Lycoposerramine-C and Phlegmariurine-A2009
- Author(s)
  A. Nakayama, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Org.Lett. 11
  
  Pages : 5554-5557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Comprehensive Flavonol Profiling and Transcriptome Coexpression Analysis Leading to Decoding Gene-Metabolite Correlation in Arabidopsis2008
- Author(s)
  Keiko Yonekura-Sakakibara, Takayuki Tohge, Fumio Matsuda, Ryo Nakabayashi, Hiromitsu Takayama, Rie Niida, Akiko Watanabe-Takahashi, Eri Inoue, Kazuki Saito
- Journal Title
  
  The Plant Cell 20
  
  Pages : 2160-2176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] First Asymmetric Total Syntheses of Cernuane-Type Lycopodium Alkaloids, Cernuine, and Cermizine D2008
- Author(s)
  Y. Nishikawa, M. Kitajima, H. Takayama
- Journal Title
  
  Org.Lett. 10
  
  Pages : 1987-1990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] MGM-9 [(E)-Methyl 2-(3-ethyl-7a, 12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo [2,3-a] quinolizin-2-yl)-3-methoxyacrylate], a Derivative of the Indole Alkaloid Mitragynine : A Novel Dual-acting μ-and κ-Opioid Agonist with Potent Antinociceptive and Weak Rewarding Effects in Mice2008
- Author(s)
  K. Matsumoto, H. Takayama, M. Narita, A. Nakamura, M. Suzuki, T. Suzuki, T. Murayama, S. Wongseripipatana, K. Misawa, M. Kitajima, K. Tashima, S. Horie
- Journal Title
  
  Neuropharmacology 55
  
  Pages : 154-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] First Total Synthesis of Trimeric Indole Alkaloid, Psychotrimine2008
- Author(s)
  Y. Matsuda, M. Kitajima, H. Takayama
- Journal Title
  
  Org.Lett. 10
  
  Pages : 125-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Comprehensive Flavonol Profiling and Transcriptome Coexpression Analysis Leading to Decoding Gene-Metabolite Correlation in Arabidopsis.2008
- Author(s)
  Keiko Yonekura-Sakakibara, Takayuki Tohge, Fumio Matsuda, Ryo Nakabayashi, Hiromitsu Takayama, Rie Niida, Akiko Watanabe-Takahashi, Eri Inoue, Kazuki Saito
- Journal Title
  
  Plant Cell 20
  
  Pages : 2160-2176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201043
[Journal Article] Two Novel Indole Alkaloids, Kopsiyunnanines A and B, from a Yunnan Kopsia2008
- Author(s)
  Y. Wu, M. Kitajima, N. Kogure, R. Zhang, H. Takayama
- Journal Title
  
  Tetrahedron Lett. 49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Design,synthesis,and biological evaluation of tricyclic heterocycle-tetraamine conjugates as potent NMDA channel blockers2007
- Author(s)
  H.Takayama, et. al.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 17
  
  Pages : 4729-4732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Design, Synthesis and Biological Evaluation of Tricyclic Heterocycle-Tetraamine Conjugates as Potent NMDA Channel Blockers2007
- Author(s)
  H. Takayama, Y. Yaegashi, M. Kitajima, X. Han, K. Nishimura, S. Okuyama, K. Igarashi
- Journal Title
  
  Bioorg.Med.Chem.Lett. 17
  
  Pages : 4729-4732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Fawcettimine-Related Alkaloids from Lycopodium serratum2007
- Author(s)
  K. Katakawa, A. Nozoe, N. Kogure, M. Kitajima, M. Hosokawa, H. Takayama
- Journal Title
  
  J.Nat.Prod. 70
  
  Pages : 1024-1028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] Asymmetric Total Syntheses of Two Phlegmarine-Type Alkaloids, Lycoposerramines-V and -W, Newly Isolated from Lycopodium serratum2007
- Author(s)
  T. Shigeyama, K. Katakawa, N. Kogure, M. Kitajima, H. Takayama
- Journal Title
  
  Org.Lett. 9
  
  Pages : 4069-4072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310137
[Journal Article] New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Application to the Preparation of Potent Opioid Receptor Agonists with a Corynanthe Skeleton.2006
- Author(s)
  H.Takayama, et al.
- Journal Title
  
  Org.Lett. 8・25
  
  Pages : 5705-5708
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Application to the Preparation of Potent Opioid Receptor Agonists with Corynanthe Skeleton.2006
- Author(s)
  H.Takayama
- Journal Title
  
  Organic Letters 8・25
  
  Pages : 5705-5708
- Data Source
  KAKENHI-PROJECT-18032019
[Journal Article] New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Application to the Preparation of Potent Opioid Receptor Agonists with a Corynanthe Skeleton.2006
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Org. Lett. 8・25
  
  Pages : 5705-5708
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Application to the Preparation of Potent Opioid Receptor Agonists with a Corynanthe Skeleton.2006
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Org.Lett. 8
  
  Pages : 5705-5708
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] Determination of absolute configuration of Pandanus alkaloid, pandamarilactonine-A, by first asymmetric total synthesis.2005
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Tetrahedron Lett. 46・35
  
  Pages : 5795-5797
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] Chemistry of Indole Alkaloids Related to the Corynanthe-Type from Uncaria, Nauclea and Mitragyna Plants.2005
- Author(s)
  H.Takayama
- Journal Title
  
  Current Organic Chemistry 9・15
  
  Pages : 1445-1464
- Data Source
  KAKENHI-PROJECT-17035016
[Journal Article] A New 9-Methoxyyohimbine-Type Alkaloid from Mitragyna africanus.2004
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Chem.Pharm.Bull. 52・3
  
  Pages : 359-361
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] New Type of Trimeric and Pentameric Indole Alkloids from Psychotria rostrata.2004
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Organic Lett. 6・17
  
  Pages : 2945-2948
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] Isolation, Structure Elucidation, and Total Synthesis of Two New Chimonanthus Alkaloids, Chimonamidine and Chimonanthidine.2004
- Author(s)
  H.Takayama et al.
- Journal Title
  
  Tetrahedron 60・4
  
  Pages : 893-900
- Data Source
  KAKENHI-PROJECT-16510156
[Journal Article] A new 9-methoxyyohimbine-type alkaloid from Mitragyna africanus.2004
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages : 359-361
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] A New 9-Methoxyyohimbine-Type Indole Alkaloid from Mitragyna africanus.2004
- Author(s)
  Takayama H.
- Journal Title
  
  Chem.Pharm.Bull. 52(3)
  
  Pages : 359-361
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Chemistry and Pharmacology of Analgesic Indole Alkaloids from the Rubiaceous Plant, Mitragyna speciosa.2004
- Author(s)
  Takayama H.
- Journal Title
  
  Chem.Pharm.Bull. 52(8)
  
  Pages : 916-9128
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Chemistry and pharmacology of analgesic indole alkaloids from Rubiaceous plant, Mitragyna speciosa.2004
- Author(s)
  Takayama, H.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages : 916-928
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] A new 9-methoxyyohimbine-type alkaloid from Mitragyna africanus.2004
- Author(s)
  Takayama, H.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages : 359-361
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Chemistry and pharmacology of analgesic indole alkaloids from Rubiaceous plant, Mitragyna speciosa.2004
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages : 916-928
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Biosynthesis of camptothecin. In silico and in vivo tracer study from [1-^<13> C] glucose2004
- Author(s)
  Yamazaki, Y., Kitajima, M., Arita, M., Takayama, H., Sudo, H., Yamazaki, M., Aimi N. and Saito, K.
- Journal Title
  
  Plant Physiol 134
  
  Pages : 161-170
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310137
[Journal Article] Camptothecin production by in vitro cultures of Ophiorrhiza liukiuensis and O. kurolwai2004
- Author(s)
  Asano, T., Watase, I., Sudo, H., Kitajima, M., Takayama, H., Aimi, N., Yamazaki, M., Saito, K.
- Journal Title
  
  Plant Biotech 21
  
  Pages : 275-281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310137
[Journal Article] First asymmetric total synthesis of Us-7and -8, novel D-seco Corynanthe-type oxindole alkaloids from Uncaria attenuata.2003
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Org.Lett. 5
  
  Pages : 2967-2970
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] First asymmetric total synthesis of Us-7 and-8,novel D-seco Corynanthe-type oxindole alkaloids from Uncaria attenuata.2003
- Author(s)
  Takayama, H.
- Journal Title
  
  Org.Lett. 5
  
  Pages : 2967-2970
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] 未利用薬用資源植物から創薬シード分子を探す2002
- Author(s)
  高山廣光
- Journal Title
  
  化学と生物 40
  
  Pages : 676-682
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Studies on the synthesis and opioid agonistic activities of mitragynine-related alkaloids. Discovery of opioid agonists structurally different from other opioid ligands2002
- Author(s)
  Takayama, H.
- Journal Title
  
  J.Med.Chem. 49
  
  Pages : 1949-1956
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Formation of an unusual dimeric compound by lead tetraacetate oxidation of a Corynanthe-type indole alkaloid, mitragynine.2002
- Author(s)
  Takayama, H.
- Journal Title
  
  Chem.Pharm.Bull. 50
  
  Pages : 960-963
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Studies on the synthesis and opioid agonistic activities of mitragynine-related alkaloids. Discovery of opioid agonists structurally different from other opioid ligands.2002
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  J.Med.Chem. 49
  
  Pages : 1949-1956
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Formation of an unusual dirneric compound by lead tetraacetate oxidation of a Corynanthe-type indole alkaloid, mitragynine.2002
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Chem.Pharm.Bull. 50
  
  Pages : 960-963
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Journal Article] Search for the seeds molecules for drug development from the untapped medicinal plant resources.2002
- Author(s)
  Takayama, H. et al.
- Journal Title
  
  Chemistry and Biology 40
  
  Pages : 676-682
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370718
[Presentation] Iboga型インドールアルカロイドVoacangine類の不斉全合成研究2017
- Author(s)
  和田凌太, 浅場絢ヌネッツ, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Bioinspired Total Syntheses of Alkaloids Isolated from Medicinal Plants2017
- Author(s)
  H. Takayama
- Organizer
  Frontiers on Medicinal Chemistry
- Place of Presentation
  Bern（スイス）
- Year and Date
  2017-02-13
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Akuammiline 型インドールアルカロイド Strictamine の形式全合成2017
- Author(s)
  佐藤圭悟, 高梨憲幸, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 加齢による脳梗塞悪化とアクロレインの関係並びに新規脳保護薬の開発2017
- Author(s)
  渡辺健太, 植村武史, 東恭平, 小暮紀行, 北島満里子, 高山廣光, 高尾浩一, 杉田義昭, 西村和洋, 五十嵐一衛, 戸井田敏彦
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 有機分子触媒を用いた立体選択的3,3-二置換ピペリジン骨格構築法の開発2017
- Author(s)
  森田暁洋, 片山健, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 不斉Claisen転位反応を鍵段階とした新規インドールアルカロイドKAM1の不斉全合成研究2017
- Author(s)
  戸田遥介, 德田涼子, 佐々木みゆき, 高橋伸明, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Kopsia jasminiflora含有新規Eburnane型アルカロイド類の不斉全合成研究2017
- Author(s)
  仲村修平, 長尾昂紀, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 新規二量体型アルカロイドLA-1の全合成研究2017
- Author(s)
  林弥沙, 中野秋香, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Fawcettimine型リコポジウムアルカロイドLycopoclavamine-Aの不斉全合成研究2017
- Author(s)
  金子弘樹, 高橋駿介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] ミソハギ科植物含有新規ビフェニルキノリジジンアルカロイド類の不斉全合成研究2017
- Author(s)
  川端遥, 平間拓, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] LycopodiumアルカロイドLycopodine類の生合成経路を模擬した不斉全合成研究2017
- Author(s)
  和田健太郎, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Ophiorrhiza nutans含有新規環状テトラペプチドON16の単離と不斉全合成研究2017
- Author(s)
  小野沢忠吉, 小暮紀行, 北島満里子, SANTIARWORN DAMMRONG, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 植物系危険ドラッグ・シニクイチHeimia salicifolia含有新規生物活性アルカロイドの探索研究2017
- Author(s)
  塚原真理, 柳沢朋美, 山口恭加, 小暮紀行, 北島満里子, 杉村康司, 飯田修, 川原信夫, 花尻(木倉)瑠理, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] インドールアルカロイドandranginineの不斉全合成と天然物の絶対立体配置について2017
- Author(s)
  通山紫乃, 三森雄二, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 新規KopsiaアルカロイドKopsiyunnanine Kの不斉全合成2016
- Author(s)
  徳田涼子, 岡本佳樹, 小山徹也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Iboga型インドールアルカロイドVoacangine類の全合成研究2016
- Author(s)
  和田凌太, 浅場絢ヌネッツ, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第42回反応と合成の進歩シンポジウム
- Place of Presentation
  静岡市清水文化会館マリナート（静岡県静岡市）
- Year and Date
  2016-11-08
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Kopsia arborea 含有インドールアルカロイドArboflorineの不斉全合成研究2016
- Author(s)
  真鍋ひとみ, 村上洋介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第21回天然薬物の開発と応用シンポジウム
- Place of Presentation
  千葉大学薬学部120周年記念講堂（千葉県千葉市）
- Year and Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] アカネ科植物Ophiorrhiza nutans含有成分の探索と化学的研究2016
- Author(s)
  小野沢忠吉, 小暮紀行, 北島満里子, Dammrong Santiarworn, 高山廣光
- Organizer
  第21回天然薬物の開発と応用シンポジウム
- Place of Presentation
  千葉大学薬学部120周年記念講堂（千葉県千葉市）
- Year and Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Kopsia arborea 含有新規 Strychnos 型関連インドールアルカロイドの構造解析2016
- Author(s)
  北島満里子, 中澤麻衣子, Yuqui Wu, 小暮紀行, Rongping Zhang, 高山廣光
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 16-(R)-Hydroxysempervirineの不斉全合成2016
- Author(s)
  鎌谷美友紀, 山田洋介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] KopsiaアルカロイドArboflorineの不斉全合成研究2016
- Author(s)
  真鍋ひとみ, 村上洋介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] ミソハギ科植物含有ビフェニルキノリジジンアルカロイド類の不斉全合成研究2016
- Author(s)
  平間拓, 梅村隆之, 柳沢朋美, 山口恭加, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 変形Fawcettimine型LycopodiumアルカロイドHuperzine Hの不斉全合成研究2016
- Author(s)
  部家有紗, 早乙女航, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 五環性モノテルペノイドインドールアルカロイドAndranginineの不斉全合成研究2016
- Author(s)
  通山紫乃, 三森雄二, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Akuammiline型インドールアルカロイドの全合成研究2016
- Author(s)
  高梨憲幸, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKAM1の不斉全合成研究2016
- Author(s)
  德田涼子, 高橋伸明, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] タイ産アカネ科 Ophiorrhiza nutans 含有アルカロイド成分探索2016
- Author(s)
  小野沢忠吉, 小暮紀行, 北島満里子, Santiarworn Dammrong, 高山廣光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Bioinspired Syntheses of Alkaloids Isolated from Medicinal Plants2016
- Author(s)
  H. Takayama
- Organizer
  The 9th CSP-KSP-JSP Joint Symposium on Pharmacognosy & 2016 Annual Conference of Committee of Chinese Traditional and Natural Medicines, Chinese Pharmaceutical Association
- Place of Presentation
  上海（中国）
- Year and Date
  2016-05-09
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 天然物の生合成に関する知見・考察をアルカロイド全合成に活かす2016
- Author(s)
  高山廣光
- Organizer
  徳島大学創薬先端合成化学セミナー
- Place of Presentation
  徳島大学薬学部（徳島県徳島市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] 生物活性アルカロイドの探索と精密構造解析2016
- Author(s)
  高山廣光
- Organizer
  理研シンポジウム: 高磁場・高感度NMR利活用促進のための天然物関連シンポジウム2016
- Place of Presentation
  理化学研究所・横浜キャンパス（神奈川県横浜市）
- Year and Date
  2016-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-16H05094
[Presentation] Fawcettimine型リコポジウムアルカロイドLycopoclavamine-Aの不斉全合成研究2015
- Author(s)
  高橋駿介, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] ヒガンバナアルカロイド生合成仮想中間体の一斉分析系の開発2015
- Author(s)
  小野寺蓮, 浅野孝, 小暮紀行, 高山廣光, 藤井勲
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 金触媒環化反応を用いたSarpagine型インドールアルカロイドの不斉全合成研究2015
- Author(s)
  渡邉慧介, 前田博行, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKAM1の不斉全合成研究2015
- Author(s)
  德田涼子, 高橋伸明, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 生物活性アルカロイドの探索・合成・創薬化学研究2015
- Author(s)
  高山廣光
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKopsiyunnanine Kのスペクトル解析及び不斉全合成による構造決定2015
- Author(s)
  北島満里子, 岡本佳樹, 小山徹也, Yuqiu Wu, 小暮紀行, Rongping Zhang, 高山廣光
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 非オピオイド様鎮痛活性を有する C5-nor stemmadenine 型インドールアルカロイドの全合成研究2015
- Author(s)
  高梨憲幸, 鈴木健太, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  千葉
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] ヒカゲノカズラ科 Lycopodium carinatum 含有アルカロイドの探索研究2015
- Author(s)
  丸山萌, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Lycodine 型アルカロイド類の生合成経路を模擬した効率的不斉全合成研究2015
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第57回天然有機化合物討論会
- Place of Presentation
  横浜
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] オクトレオチドユニットを配したコルヒチン系ダブルプロドラッグ化合物の創製研究2015
- Author(s)
  北島満里子, 遠藤慎平, 森田暁洋, 小暮紀行, 高山廣光
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  千葉
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 五環性モノテルペノイドインドールアルカロイド Andranginine の不斉全合成研究2015
- Author(s)
  通山紫乃, 三森雄二, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  千葉
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規骨格Lycopodiumアルカロイド(–)-Lycoposerramine-Rの不斉全合成2015
- Author(s)
  石田寛明, 木村真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 金触媒環化反応を用いたサルパギン型インドールアルカロイドの不斉全合成2015
- Author(s)
  渡辺慧介, 前田博行, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第41回反応と合成の進歩シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] キョウチクトウ科植物Kopsia arborea含有新規インドールアルカロイドKopsiyunnanines E, I, J1, J22014
- Author(s)
  村上洋介, 小山徹也, 鈴木悠太, 高橋伸明, Yuqui Wu , 小暮紀行, Rongping Zhang, 北島満里子, 高山廣光
- Organizer
  第56回天然有機化合物討論会
- Place of Presentation
  高知
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規骨格 Lycopodium アルカロイド Lycoposerramine-R の不斉全合成研究2014
- Author(s)
  石田寛明, 木村真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第40回反応と合成の進歩シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2014-11-10
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 温度感受性TRPチャネルアンタゴニスト活性を有するVoacangine関連化合物の全合成研究と構造活性相関2014
- Author(s)
  北島満里子，寺田祐子，田口芙悠美，浅場絢ヌネッツ，小暮紀行，渡辺達夫，高山廣光
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Voacangine類縁化合物を用いた構造―活性相関研究化学アゴニスト選択的TRPM8阻害に重要な構造の同定2014
- Author(s)
  寺田祐子, 北島満里子, 田口芙悠美, 高山廣光, 堀江俊治, 渡辺達夫
- Organizer
  第29回日本香辛料研究会学術講演会
- Place of Presentation
  札幌
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Lycopodiumアルカロイド Lycodineの生合成経路を模擬した短段階不斉全合成2014
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第105回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-06-10
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] キョウチクトウ科Kopsia arborea含有インドールアルカロイドの探索2014
- Author(s)
  北島満里子, 小山徹也, Yuqiu Wu, 小暮紀行, Rongping Zhang, 高山廣光
- Organizer
  日本生薬学会第61回年会
- Place of Presentation
  福岡
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 生物活性天然物の探索と全合成-創薬研究に向けて2013
- Author(s)
  高山廣光
- Organizer
  創薬懇話会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Bioinspired Short Asymmetric Total Synthesis of Lycopodium Alkaloid, (-)-Lycodine2013
- Author(s)
  M. Azuma, N. Kogure, M. Kitajima, H. Takayama
- Organizer
  3rd Junior International Conference on Cutting-Edge Organic Chemistry in Asia
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規骨格LycopodiumアルカロイドLycoposerramine-Rの不斉全合成研究2013
- Author(s)
  石田寛明,木村真也,小暮紀行,北島満里子,高山廣光
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2012
- Author(s)
  高山廣光
- Organizer
  有機合成2月セミナー「有機合成のニュートレンド2012」
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] アルカロイドの探索と全合成研究から得られるもの2012
- Author(s)
  高山廣光
- Organizer
  第47回天然物化学談話会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2012
- Author(s)
  高山廣光
- Organizer
  明治薬科大学ハイテクリサーチセンター平成20-24年度研究成果発表会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索から全合成へ. そして創薬研究へ2012
- Author(s)
  高山廣光
- Organizer
  平成24年度前期（春期）有機合成化学講習会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 栃木県産Lycopodiumserratum含有アルカロイドの成分探索2012
- Author(s)
  池城沙耶子,北島満里子,小暮紀行,片川和明,高山廣光
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2012
- Author(s)
  高山廣光
- Organizer
  有機合成2月セミナー「有機合成のニュートレンド2012」
- Place of Presentation
  大阪
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Pauson-Khand反応を基盤としたFawcettimineの不斉全合成研究2012
- Author(s)
  中山淳,小暮紀行,北島満里子,高山廣光
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 有機合成化学の醍醐味-戦略的アプローチの最前線-2012
- Author(s)
  高山廣光
- Organizer
  生物活性アルカロイドの探索から全合成へ.そして創薬研究へ.平成24年度前期(春期)有機合成化学講習会
- Place of Presentation
  東京
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] アルカロイドの探索と全合成研究から得られるもの2012
- Author(s)
  高山廣光
- Organizer
  第47回天然物化学談話会
- Place of Presentation
  熊本
- Year and Date
  2012-07-04
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2011
- Author(s)
  高山廣光
- Organizer
  第6回有機合成化学のフロンティア
- Place of Presentation
  和光(招待講演)
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 生物活性アルカロイドの探索と全合成2011
- Author(s)
  高山廣光
- Organizer
  理研シンポジウム第6回有機合成化学のフロンティア
- Place of Presentation
  和光
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Fawcettimine型リコポジウムアルカロイドHuperzine-Qの不斉全合成2011
- Author(s)
  中山淳,小暮紀行,北島満里子,高山廣光
- Organizer
  第99回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Synthetic Study of Lycoposerramine-R, A Novel Skeletal Type of Lycopodium Alkaloids2011
- Author(s)
  S. Kimura, N. Kogure, M. Kitajima, and H. Takayama
- Organizer
  8th AFMC International Medicinal Chemistry Symposium (AIMECS11)
- Place of Presentation
  Tokyo
- Year and Date
  2011-12-30
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Synthetic Studies of Fawcettimine-type Lycopodium Alkaloids, Potential Seed Molecules for Drug Development2011
- Author(s)
  A. Nakayama, N. Kogure, M. Kitajima,and H. Takayama
- Organizer
  8th AFMC International Medicinal Chemistry Symposium (AIMECS11)
- Place of Presentation
  Tokyo
- Year and Date
  2011-12-30
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] リコポジウム属植物トウゲシバ含有アルカロイドの探索と化学.2010
- Author(s)
  高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Pauson-Khand反応を基盤としたfawcettimine型リコポジウムアルカロイド類の不斉全合成研究2010
- Author(s)
  中山淳,小暮紀行,北島満里子,高山廣光
- Organizer
  第36回反応と合成の進歩シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] Investigation and Syntheses of Novel Analgesic Indole Alkaloids in Rubiaceous Medicinal Plants2010
- Author(s)
  H. Takayama
- Organizer
  The 1^<st> Joint Symposium on Pharmaceutical Sciences between College of Pharmacy, Seoul National University and Graduate School ofPharmaceutical Sciences, Chiba University - Cutting-Edge Research on Natural Products -
- Place of Presentation
  Chiba
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] 不斉 Claisen 転位を鍵段階とした三量体型インドールアルカロイド Psychotrimine の不斉全合成2010
- Author(s)
  高橋伸明, 伊藤健, 松田洋平, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Investigation and Syntheses of Novel Analgesic Indole Alkaloids in Rubiaceous Medicinal Plants.2010
- Author(s)
  H.Takayama
- Organizer
  The 1^<st> Joint Symposium on Pharmaceutical Sciences between College of Pharmacy, Seoul National University and Graduate School of Pharmaceutical Sciences, Chiba University
- Place of Presentation
  千葉
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22390019
[Presentation] オピオイド性鎮痛アルカロイド mitragynine の構造活性相関研究2010
- Author(s)
  小柳美寿々, 中山輝美, 三澤香織, 小暮紀行, 北島満里子, 松本健次郎, 堀江俊治, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] ヒカゲノカズラ科植物2種より単離した新規アルカロイド類の構造2010
- Author(s)
  片川和明, 小暮紀行, 北島満里子, 本澤勝年, 有澤宗久, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Lycoposerramine-Cおよび-Sの不斉全合成研究2010
- Author(s)
  中山淳, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] リコポジウム属植物トウゲシバ含有アルカロイドの探索と化学2010
- Author(s)
  高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 中国雲南省産 Kopsia arborea 含有新規アルカロイド成分の探索研究2010
- Author(s)
  佐々木みゆき, 〓〓秋, 北島満里子, 小暮紀行, 張栄平, 高山廣光
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 新規 Kopsia アルカロイド Kopsiyunnanine Eの不斉全合成研究2009
- Author(s)
  高橋伸明, 〓〓秋, 北島満里子, 高山廣光
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] タイ産 Lycopodiumu squarrosam 含有アルカロイドの成分探索2009
- Author(s)
  見藤裕子, 北島満里子, 小暮紀行, 高山廣光
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 化学研究デザイン塾創薬をリードする新しい機能性天然分子の発見と創薬を目指して2009
- Author(s)
  高山廣光
- Organizer
  第26回和漢薬医薬学会
- Place of Presentation
  千葉
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Lycopodium serratum 由来新規 Lycopodium アルカロイド類の不斉全合成2009
- Author(s)
  中山淳, 田中智之, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第51回天然有機化合物討論会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-07
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 抗腫瘍性新規三量体型インドールアルカロイド Psychotrimine の不斉全合成2009
- Author(s)
  高橋伸明, 伊藤健, 松田洋平, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] シロイヌナズナにおける二つのMYB遺伝子同時過剰発現による遺伝子発現及びフラボノイド蓄積への効果2009
- Author(s)
  中林亮,榊原圭子,松田史生,峠隆之,北島満里子,高山廣光,山崎真巳,斉藤和季
- Organizer
  第4回メタボロームシンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] 新規リコポジウムアルカロイド Lycoposerramine Cの不斉全合成研究2009
- Author(s)
  中山淳, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] シロイヌナズナにおける二つのMYB遺伝子同時過剰発現による遺伝子発現及びフラボノイド蓄積への効果2009
- Author(s)
  中林亮, 榊原圭子, 松田史生, 峠隆之, 北島満里子, 高山廣光, 山崎真巳, 斉藤和季
- Organizer
  第4回メタボロームシンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] 化学研究デザイン塾創薬をリードする新しい機能性天然分子発見と創薬を目指して.2009
- Author(s)
  高山廣光
- Organizer
  第26回和漢薬医薬学会学術大会
- Place of Presentation
  千葉
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Cernuine および関連リコポジウムアルカロイド類の全合成2008
- Author(s)
  西川泰弘, 北島満里子, 高山廣光
- Organizer
  第93回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Quinolizidine 型リコポジウムアルカロイド類の全合成研究2008
- Author(s)
  西川泰弘, 北島満里子, 高山廣光
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Novel Indole Alkaloids, Kopsiyunnanines A～D from Kopsia officinalis2008
- Author(s)
  〓〓秋, 末弘真有, 高橋伸明, 小暮紀行, 北島満里子, 高山廣光, 張栄平
- Organizer
  第50回天然有機化合物討論会
- Place of Presentation
  福岡
- Year and Date
  2008-09-30
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 新規リコポジウムアルカロイド Lycoposerramine-XおよびZの不斉全合成研究2008
- Author(s)
  田中智之, 重山貴秀, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第27回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-11-26
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Flavonoid profiling and transcriptome in Arabidopsis overexpressing two MYB genes.2008
- Author(s)
  R.Nakabayashi, K.Yonekura-Sakakibara, F.Matsuda, T.Tohge, M.Kitajima, H.Takayama, M.Yamazaki, K.Saito
- Organizer
  5^<th> International Conference on Plant Metabolomics.
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] 新規四量体型インドールアルカロイド psychotetramine の全合成研究2008
- Author(s)
  松田洋平, 北島満里子, 高山廣光
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 中国雲南省産 Kopsia officinalis より新規アルカロイドの探索2008
- Author(s)
  〓〓秋, 小暮紀行, 北島満里子, 張栄平, 高山廣光
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] オピオイド性鎮痛アルカロイド、mitragynine を基盤とした構造活性相関研究2008
- Author(s)
  中山輝美, 松本健次郎, 北島満里子, 堀江俊治, 高山廣光
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 二つのMYB遺伝子の同時過剰発現体におけるトランスクリプトームとフラボノイドプロファイル2008
- Author(s)
  中林亮,榊原圭子,松田史生,北島満里子,高山廣光,山崎真巳,斉藤和季
- Organizer
  第26回日本植物細胞分子生物学会大阪大会・シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] Flavonoid profiling and transcriptome in Arabidopsis overexpressing two MYB genes2008
- Author(s)
  R.Nakabayashi, K.Yonekura-Sakakibara, F.Matsuda, T.Tohge, M.Kitajima, H.Takayama, M.Yamazaki, K.Saito
- Organizer
  5^<th> International Conference on Plant Metabolomics
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] 二つのMYB遺伝子の同時過剰発現体におけるトランスクリプトームとフラボノイドプロファイル2008
- Author(s)
  中林亮, 榊原圭子, 松田史生, 北島満里子, 高山廣光, 山崎真巳, 斉藤和季
- Organizer
  第26回日本植物細胞分子生物学会大阪大会・シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19201043
[Presentation] 三環性複素環とポリアミンのハイブリッド型構造を有する新規NMDA受容体阻害剤の創製研究2007
- Author(s)
  八重樫優一, 北島満里子, 韓霞, 西村和洋, 奥山茂, 五十嵐一衛, 高山廣光
- Organizer
  第26回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Quinolizidine 型リコポジウムアルカロイド類のダイバージェント合成研究2007
- Author(s)
  西川泰弘, 北島満里子, 高山廣光
- Organizer
  第33回反応と合成の進歩シンポジウム
- Place of Presentation
  長崎
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] 新規三量体型インドールアルカロイド psychotrimine の全合成2007
- Author(s)
  松田洋平, 森郁江, 北島満里子, 高山廣光
- Organizer
  第49回天然有機化合物討論会
- Place of Presentation
  札幌
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Investigation and Synthesis of Novel Analgesic Indole Alkaloids in Rubiaceous Medicinal Plants.2007
- Author(s)
  H. Takayama
- Organizer
  The JSPS 2nd Medicinal Chemistry Seminor of Asia/Africa Science Olatform Program
- Place of Presentation
  Phuket (Thailand)
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-18032019
[Presentation] 新規 Phlegmarine 型リコポジウムアルカロイド Lycoposerramine-VおよびWの不斉全合成2007
- Author(s)
  重山貴秀, 片川和明, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第92回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-19310137
[Presentation] Voacanga africana含有生物活性新規インドールアルカロイドの探索と不斉全合成研究
- Author(s)
  浅場絢ヌネッツ, 原田真也, 岩井真澄, Mee Wah Lo, 小暮紀行, 北島満里子, 花尻（木倉）瑠理, 合田幸広, 高山廣光
- Organizer
  第55回天然有機化合物討論会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKAM1の不斉全合成研究
- Author(s)
  德田涼子, 高橋伸明, 佐々木みゆき, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規iboga型インドールアルカロイドの不斉全合成研究
- Author(s)
  浅場絢ヌネッツ, 原田真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] ミソハギ科植物含有新規ビフェニルキノリチジンアルカロイド類の全合成研究
- Author(s)
  梅村隆之, 瓦井克孝, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Akuammiline型インドールアルカロイドGomalineの全合成研究
- Author(s)
  高梨憲幸, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] オピオイド性鎮痛インドールアルカロイドMitragynine誘導体の医薬化学的研究
- Author(s)
  片山健, 井上峻, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 腫瘍細胞選択性を指向したコルヒチン系ダブルプロドラッグ化合物の合成研究
- Author(s)
  遠藤慎平, 八十歩直子, 北島満里子, 小暮紀行, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規骨格LycopodiumアルカロイドLycoposerramine-Rの不斉全合成研究
- Author(s)
  石田寛明, 木村真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規KopsiaアルカロイドKopsiyunnanune Eの不斉全合成研究
- Author(s)
  村上洋介, 高橋伸明, 呉煜秋, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] KopsiaアルカロイドAndranginineの全合成研究
- Author(s)
  三森雄二, 玉田卓矢, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 新規Colchicine誘導体の合成を抗腫瘍効果
- Author(s)
  西山裕之, 小野雅弘, 杉本卓弥, 笹井俊雄, 浅川直之, 上野哲, 富永恵隆, 八重樫隆, 長岡正人, 松崎健, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Voacanga africana由来アルカロイドVoacangineのThrmo-TRPsへの作用
- Author(s)
  寺田祐子, 堀江俊治, 高山廣光, 渡辺達夫
- Organizer
  第28回日本香辛料研究会学術講演会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] LycopodiumアルカロイドLycodineの生合成経路を模擬した短段階不斉全合成
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第39回反応と合成の進歩シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Lycopodium nummularifolium含有のアルカロイドの探索研究
- Author(s)
  岡部慧, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 金触媒環化反応を用いたSarpagine型インドールアルカロイドの全合成研究
- Author(s)
  前田博行, 鈴木健太, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] LycopodiumアルカロイドLycodineの生合成経路を模擬した短段階不斉全合成
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] シロイヌナズナ花粉特異的フラボノールの高次配糖化酵素遺伝子の機能同定とその局在性
- Author(s)
  榊原圭子, 中林亮, 菅原聡子, 峠隆之, 伊藤卓也, 小柳美寿々, 北島満里子, 高山廣光, 斉藤和季
- Organizer
  第55回植物生理学会年会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] 金触媒環化反応を用いたAkuammiline型インドールアルカロイドの全合成研究
- Author(s)
  高梨憲幸, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第48回天然物化学談話会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] キョウチクトウ科Kopsia arborea含有インドールアルカロイドの構造解析
- Author(s)
  北島満里子, 小山徹也, Yuqui Wu, 小暮紀行, Rongping Zhang, 高山廣光
- Organizer
  日本生薬学会第60回年会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] Lycoposerramine-Rの不斉全合成研究
- Author(s)
  石田寛明, 木村真也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第48回天然物化学談話会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] LycopodiumアルカロイドLycodineの生合成経路を模擬した不斉全合成研究
- Author(s)
  東雅之, 良川哲也, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第48回天然物化学談話会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-25293023
[Presentation] フキ (Petasites japonicus) に含有されるピロリジジンアルカロイド類の検索研究
- Author(s)
  岡部慧, 小暮紀行, 北島満里子, 高山廣光
- Organizer
  第5回食品薬学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293023

1. KITAJIMA Mariko (60195261)

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40. 山口健太郎 (50159208)

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# of Collaborated Products : 0results
41. 谷時雄 (80197516)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
42. OBITZ Peter

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
43. TONGROCH Pavich

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
44. ZENK M.H.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
45. STOECKIGT Joachim

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
46. ZENK Meinhart H.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
47. ZENK M.K.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
48. CARL M Ruyte

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
49. JOACHIM Stoe

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
50. PANG Peter K

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
51. KTPANG Peter

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
52. JOACHIM Stoc

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
53. PAVICH Tongr

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
54. JOACHIM Sto

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
55. PETER KT Pa

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
56. DHAVADEE Po

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
57. PAVICH Tong

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
58. PETER KT Pan

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
59. WATANABE Tatsuo

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
60. UCHIDA Kunitoshi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
61. NARITA Minoru

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
62. SUZUKI Tsutomu

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

TAKAYAMA Hiromitsu 高山 廣光

Research Projects

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Co-Researchers

Collective synthesis of monoterpenoid indole alkaloid using bioinspired reactionsOngoing

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アルカロイド由来の新規有機不斉触媒と特定配列オリゴヌクレオチド認識分子の創製Principal InvestigatorOngoing

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植物アルカロイドの探索と合成研究を基盤とした、疼痛および脳機能改善薬の創成Principal InvestigatorOngoing

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Studies on the synthesis of SPECT probe to elucidate the in vivo dynamics of natural opioidsPrincipal Investigator

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Search for natural molecules that control memory and pain from medicinal resources and drug development reserachPrincipal Investigator

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Studies on isolation, total synthesis and medicinal chemistryof natural products with regulating activities on memory and pain.Principal Investigator

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新規NMDA受容体チャネルブロッカー探索による脳機能改善薬の創製Principal Investigator

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Search, asymmetric synthesis, and medicinal chemistry study on the plant alkaloids that regulate the brain nervous system.Principal Investigator

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オピオイド受容体サブタイプを分子標的とする機能性コリナンテ型アルカロイドの開発Principal Investigator

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モルヒネを超える新規オピオイド性鎮痛アルカロイドの探索と創製Principal Investigator

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TAKAYAMA Hiromitsu 高山廣光