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OGIHARA Yukio  荻原 幸夫

ORCIDConnect your ORCID iD *help
Researcher Number 70080166
Affiliation (based on the past Project Information) *help 2003 – 2004: 名城大学, 薬学部, 教授
1997 – 2001: 名古屋市立大学, 薬学部, 教授
1998: 教授
1987 – 1993: 名古屋市立大学, 薬学部, 教授
1986: Faculty of Pharmaceutical Sciences, Nagoya City University, 薬学部, 教授
Review Section/Research Field
Principal Investigator
Chemical pharmacy / General internal medicine (including Psychosomatic medicine)
Except Principal Investigator
Biological pharmacy / General internal medicine (including Psychosomatic medicine) / Chemical pharmacy / Environmental pharmacy
Keywords
Principal Investigator
saikosaponin a / saikosaponin c / saikosaponin d / 漢方方剤 / コルチコステロン / Trypanosoma / Gallic acid / T.vivax(IL1392) / FK506 binding protein 12 / Peptidyl-prolyl cis-trans isomerase … More / Histone H3 / キカラスウリ / カラスリン / 堕胎薬 / アミノ酸配列 / 抗腫瘍活性 / タンパク質多型 / 土壌細菌 / 毛状根培養 / Plant protein / Karasurin / Trichosanthes kirilowii var,japonicum / Abortifacient protein / Antiーtumor protein / Amino and sequence / Isoelectrie focusing / BeWo cell / 小柴胡湯 / 大柴胡湯 / マクロファ-ジ / インタ-ロイキンー1 / サイコサポニン / 溶血 / 貧食能 / グリチルリチン / 複合成分 / 生薬配合 / 大柴胡夜 / サポニン / 薬理作用 / Kampo prescription / Shosaikoto / Daisaikoto / Macrophage / Interleukin-1 / Saikosaponin / Hemolytic action / Phagocytosis / T.ivirax(IL1392) / T.bruci gambiense(Wellcome株) / 抗トリパノソーマ活性 / 細胞致死活性 / Fuchsia hybrida / 花粉 / 走化反応 / T.bruci gambiense(Wellcome Strain / Anti-Trypanosoma activity / Cytotoxic activity / 没食子酸 / ヒガンバナアルカロイド / アポトーシス / 選択性 / FK506 binding protein12 / 没食子酸誘導体 / 細胞死 / カルシウム / 活性酸素 / Gallic Acid / Zephyranthes alkaloids / Apoptosis / Selectivity / アトピー性皮膚炎 / 十全大補湯 / NCマウス / 2,4,6-trinitrochlorobenzene / 制御性T細胞 / ハプテン / 2,4,6-trinitrochlorobenzne / トランスクリプトーム解析 / atopic dermatitis / Kampo medicine / Juzen-taiho-to / NC mice / 2.4.6-trinitrochlorobenzene / regulatory T cell / サイコサポニンa / サイコサポニンd / サイコサポニンc / 腸内細菌 / 構造活性相関 / 下垂体-副腎系刺激作用 / アルカリ反解反応 / intestinal flora / structure-activity relationship / pituitary - adrenocortical axis function / corticosterone / アルコール性アルカリ金属 / 糖鎖切断反応 / Saikosaponin a / Saikosoporin c / Saikosoporin d / コルチコステロン分泌活性 / 赤血球溶血 / 赤血球膜への吸着 / 消化管内代謝物 / 赤血球溶血態 / 細胞膜への吸着 / 20(S)ーginsenosideーRg_2 / alcoholic alkali metal / cleavage of glycosidic bond / corticosterone-secretion / hemolysis … More
Except Principal Investigator
漢方薬 / RFLP / Cinnamomum / Aquilaria / 民族伝統薬物 / 薬物相互作用 / 薬物代謝酵素 / 網羅的遺伝子発現 / SAGE法 / 網羅的遺伝子発現解析 / 漢薬資源 / 品質評価 / 栽培 / 組織培養 / 生物活性 / 繁殖 / 分類 / 漢薬資源植物 / 培養 / 成分 / Chinese medicinal plants / Evaluation / Cultivation / Tissue culture / Biological activity / Breeding / Classification / アクテオシド / フェニルエタノイド配糖体 / 過酸化水素 / マクロファージ / 内皮細胞 / TNF-α / IL-1β / IL-6 / ICAM-1 / シグナル伝達 / Acteoside / Phenylethanoid glycoside / Hydrogen peroxide / Macrophage / Endothelial cell / ベトナム / 桂皮 / 沈香 / フィールドワーク / 薫香料 / 薬用植物 / Vietnam / cinnamon / agarwood / field work / incense / medicinal plants Less
  • Research Projects

    (12 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (25 People)
  •  漢方薬と西洋薬の相互作用をゲノムワイドに探る

    • Principal Investigator
      水上 元
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Nagoya City University
  •  Basic and clinical evaluation of Juzen-taiho-to usedin atopic dermatitisPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Meijo University
  •  Study on the production of medicinal plants characteristic of Vietnam based on the field work.

    • Principal Investigator
      HONDA Gisho
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for University and Society Collaboration
    • Research Field
      Environmental pharmacy
    • Research Institution
      KYOTO UNIVERSITY
  •  Investigation of natural products with selective cytotoxicity against tumor cellsPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  Phenylethanoid glycosides as a new macrophage-activating factor

    • Principal Investigator
      INOUE Makoto
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University
  •  植物タンパクの医薬品への応用開発Principal Investigator

    • Principal Investigator
      荻原 幸夫
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  漢方薬を中心とした民族伝統薬物の先端技術による医薬学的解明と科学的確立

    • Principal Investigator
      菊池 徹
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  The chemical attractant against T.virax from pollen grainsPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya City University
  •  EVALUATION AND DEVELOPMENT OF CHINESE MEDICINAL PLANTS.

    • Principal Investigator
      NAKAJIMA Terumi
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Significance of Crude Drug Composition and Plural Components in Kampo Prescription.Principal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  Cleavage of glycosidic bond in alcoholic alkali metal solutionPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  Structural transformation of saikosaponins by intestinal flora and structure - activity relationship between their derivatives in anti - inflammatory actionPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University

All 2005 2003

All Journal Article

  • [Journal Article] Dermal mast cells play a central role on the incidence of scratching behavior in mice induced by multiple application of the hapten, 2,4,6-trinitrochlorobenzene2005

    • Author(s)
      H.Yamashita, Y.Michibata, H.Mizukami, Y.Ogihara, A.Morita, M.Nose
    • Journal Title

      Experimental Dermatology 14・2

      Pages: 438-444

    • Data Source
      KAKENHI-PROJECT-16659175
  • [Journal Article] Sho-saiko-to and Saiko-keishi-to, the traditional Chinese and Japanese herbal medicines, altered hepatic drug-metabolizing enzymes in mice and rats when administered orally for long time2003

    • Author(s)
      Nose, M., Tamura, M., Ryu, N., Mizukami, H., Ogihara, Y.
    • Journal Title

      Journal of Pharmacy and Pharmacology 50

      Pages: 1419-1426

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590607
  • 1.  NOSE Mituhiko (60228327)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 2.  INOUE Makoto (50191888)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  TAKEDA Tadahiro (90106253)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  AMAGAYA Sakae (80137124)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  YABU Yoshisada (70080083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NAKAJIMA Terumi (50012597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  NOHARA Toshihiro (30037600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YOSHIDA Takashi (20025696)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TSUDA Yoshisuke (40077508)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MURAKOSHI Isamu (30009162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  UENO Akira (30046247)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KOJIMA Keisuke (40275144)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HONDA Gisho (00093310)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ITO Michiho (30283592)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KIUCHI Fumiyuki (60161402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  菊池 徹 (40025680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  渡辺 裕司 (10012642)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  渡辺 和夫 (80019124)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  野村 靖幸 (00034041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  木村 正康 (60019099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  水上 元 (30128219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  田端 守 (60025682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  奥田 拓男 (90025677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  HIRUMI Hiroyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SHIMADA Yasuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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