OGIHARA Yukio 荻原幸夫

Researcher Number	70080166
Affiliation (based on the past Project Information) *help	2003 – 2004: 名城大学, 薬学部, 教授 1997 – 2001: 名古屋市立大学, 薬学部, 教授 1998: 教授 1987 – 1993: 名古屋市立大学, 薬学部, 教授 1986: Faculty of Pharmaceutical Sciences, Nagoya City University, 薬学部, 教授
Review Section/Research Field	Principal Investigator Chemical pharmacy / General internal medicine (including Psychosomatic medicine) Except Principal Investigator Biological pharmacy / General internal medicine (including Psychosomatic medicine) / Chemical pharmacy / Environmental pharmacy
Keywords	Principal Investigator saikosaponin a / saikosaponin c / saikosaponin d / 漢方方剤 / コルチコステロン / Trypanosoma / Gallic acid / T.vivax(IL1392) / FK506 binding protein 12 / Peptidyl-prolyl cis-trans isomerase … More / Histone H3 / キカラスウリ / カラスリン / 堕胎薬 / アミノ酸配列 / 抗腫瘍活性 / タンパク質多型 / 土壌細菌 / 毛状根培養 / Plant protein / Karasurin / Trichosanthes kirilowii var,japonicum / Abortifacient protein / Antiーtumor protein / Amino and sequence / Isoelectrie focusing / BeWo cell / 小柴胡湯 / 大柴胡湯 / マクロファ-ジ / インタ-ロイキンー1 / サイコサポニン / 溶血 / 貧食能 / グリチルリチン / 複合成分 / 生薬配合 / 大柴胡夜 / サポニン / 薬理作用 / Kampo prescription / Shosaikoto / Daisaikoto / Macrophage / Interleukin-1 / Saikosaponin / Hemolytic action / Phagocytosis / T.ivirax(IL1392) / T.bruci gambiense(Wellcome株) / 抗トリパノソーマ活性 / 細胞致死活性 / Fuchsia hybrida / 花粉 / 走化反応 / T.bruci gambiense(Wellcome Strain / Anti-Trypanosoma activity / Cytotoxic activity / 没食子酸 / ヒガンバナアルカロイド / アポトーシス / 選択性 / FK506 binding protein12 / 没食子酸誘導体 / 細胞死 / カルシウム / 活性酸素 / Gallic Acid / Zephyranthes alkaloids / Apoptosis / Selectivity / アトピー性皮膚炎 / 十全大補湯 / NCマウス / 2,4,6-trinitrochlorobenzene / 制御性T細胞 / ハプテン / 2,4,6-trinitrochlorobenzne / トランスクリプトーム解析 / atopic dermatitis / Kampo medicine / Juzen-taiho-to / NC mice / 2.4.6-trinitrochlorobenzene / regulatory T cell / サイコサポニンa / サイコサポニンd / サイコサポニンc / 腸内細菌 / 構造活性相関 / 下垂体-副腎系刺激作用 / アルカリ反解反応 / intestinal flora / structure-activity relationship / pituitary - adrenocortical axis function / corticosterone / アルコール性アルカリ金属 / 糖鎖切断反応 / Saikosaponin a / Saikosoporin c / Saikosoporin d / コルチコステロン分泌活性 / 赤血球溶血 / 赤血球膜への吸着 / 消化管内代謝物 / 赤血球溶血態 / 細胞膜への吸着 / 20(S)ーginsenosideーRg_2 / alcoholic alkali metal / cleavage of glycosidic bond / corticosterone-secretion / hemolysis … More Except Principal Investigator 漢方薬 / RFLP / Cinnamomum / Aquilaria / 民族伝統薬物 / 薬物相互作用 / 薬物代謝酵素 / 網羅的遺伝子発現 / SAGE法 / 網羅的遺伝子発現解析 / 漢薬資源 / 品質評価 / 栽培 / 組織培養 / 生物活性 / 繁殖 / 分類 / 漢薬資源植物 / 培養 / 成分 / Chinese medicinal plants / Evaluation / Cultivation / Tissue culture / Biological activity / Breeding / Classification / アクテオシド / フェニルエタノイド配糖体 / 過酸化水素 / マクロファージ / 内皮細胞 / TNF-α / IL-1β / IL-6 / ICAM-1 / シグナル伝達 / Acteoside / Phenylethanoid glycoside / Hydrogen peroxide / Macrophage / Endothelial cell / ベトナム / 桂皮 / 沈香 / フィールドワーク / 薫香料 / 薬用植物 / Vietnam / cinnamon / agarwood / field work / incense / medicinal plants Less

漢方薬と西洋薬の相互作用をゲノムワイドに探る
- Principal Investigator
  
  水上元
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Nagoya City University
Basic and clinical evaluation of Juzen-taiho-to usedin atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Meijo University
Study on the production of medicinal plants characteristic of Vietnam based on the field work.
- Principal Investigator
  
  HONDA Gisho
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  Environmental pharmacy
- Research Institution
  KYOTO UNIVERSITY
Investigation of natural products with selective cytotoxicity against tumor cellsPrincipal Investigator
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nagoya City University
Phenylethanoid glycosides as a new macrophage-activating factor
- Principal Investigator
  
  INOUE Makoto
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
植物タンパクの医薬品への応用開発Principal Investigator
- Principal Investigator
  
  荻原幸夫
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nagoya City University
漢方薬を中心とした民族伝統薬物の先端技術による医薬学的解明と科学的確立
- Principal Investigator
  
  菊池徹
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toyama Medical and Pharmaceutical University
The chemical attractant against T.virax from pollen grainsPrincipal Investigator
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya City University
EVALUATION AND DEVELOPMENT OF CHINESE MEDICINAL PLANTS.
- Principal Investigator
  
  NAKAJIMA Terumi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  THE UNIVERSITY OF TOKYO
Significance of Crude Drug Composition and Plural Components in Kampo Prescription.Principal Investigator
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nagoya City University
Cleavage of glycosidic bond in alcoholic alkali metal solutionPrincipal Investigator
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nagoya City University
Structural transformation of saikosaponins by intestinal flora and structure - activity relationship between their derivatives in anti - inflammatory actionPrincipal Investigator
- Principal Investigator
  
  OGIHARA Yukio
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nagoya City University

All 2005 2003

All Journal Article

[Journal Article] Dermal mast cells play a central role on the incidence of scratching behavior in mice induced by multiple application of the hapten, 2,4,6-trinitrochlorobenzene2005
- Author(s)
  H.Yamashita, Y.Michibata, H.Mizukami, Y.Ogihara, A.Morita, M.Nose
- Journal Title
  
  Experimental Dermatology 14・2
  
  Pages: 438-444
- Data Source
  KAKENHI-PROJECT-16659175
[Journal Article] Sho-saiko-to and Saiko-keishi-to, the traditional Chinese and Japanese herbal medicines, altered hepatic drug-metabolizing enzymes in mice and rats when administered orally for long time2003
- Author(s)
  Nose, M., Tamura, M., Ryu, N., Mizukami, H., Ogihara, Y.
- Journal Title
  
  Journal of Pharmacy and Pharmacology 50
  
  Pages: 1419-1426
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590607

1. NOSE Mituhiko (60228327)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
2. INOUE Makoto (50191888)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. TAKEDA Tadahiro (90106253)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. AMAGAYA Sakae (80137124)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YABU Yoshisada (70080083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKAJIMA Terumi (50012597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NOHARA Toshihiro (30037600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIDA Takashi (20025696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TSUDA Yoshisuke (40077508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MURAKOSHI Isamu (30009162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. UENO Akira (30046247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KOJIMA Keisuke (40275144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HONDA Gisho (00093310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ITO Michiho (30283592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KIUCHI Fumiyuki (60161402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 菊池徹 (40025680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 渡辺裕司 (10012642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 渡辺和夫 (80019124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 野村靖幸 (00034041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 木村正康 (60019099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 水上元 (30128219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 田端守 (60025682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 奥田拓男 (90025677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. HIRUMI Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SHIMADA Yasuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OGIHARA Yukio 荻原 幸夫

Research Projects

Research Products

Co-Researchers

漢方薬と西洋薬の相互作用をゲノムワイドに探る

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic and clinical evaluation of Juzen-taiho-to usedin atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the production of medicinal plants characteristic of Vietnam based on the field work.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of natural products with selective cytotoxicity against tumor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Phenylethanoid glycosides as a new macrophage-activating factor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

植物タンパクの医薬品への応用開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

漢方薬を中心とした民族伝統薬物の先端技術による医薬学的解明と科学的確立

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The chemical attractant against T.virax from pollen grainsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

EVALUATION AND DEVELOPMENT OF CHINESE MEDICINAL PLANTS.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Significance of Crude Drug Composition and Plural Components in Kampo Prescription.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cleavage of glycosidic bond in alcoholic alkali metal solutionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural transformation of saikosaponins by intestinal flora and structure - activity relationship between their derivatives in anti - inflammatory actionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Dermal mast cells play a central role on the incidence of scratching behavior in mice induced by multiple application of the hapten, 2,4,6-trinitrochlorobenzene2005

Author(s)

Journal Title

Data Source

[Journal Article] Sho-saiko-to and Saiko-keishi-to, the traditional Chinese and Japanese herbal medicines, altered hepatic drug-metabolizing enzymes in mice and rats when administered orally for long time2003

OGIHARA Yukio 荻原幸夫