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OGIHARA Yukio  荻原 幸夫

ORCIDConnect your ORCID iD *help
Researcher Number 70080166
Affiliation (based on the past Project Information) *help 2003 – 2004: 名城大学, 薬学部, 教授
1997 – 2001: 名古屋市立大学, 薬学部, 教授
1998: 教授
1987 – 1993: 名古屋市立大学, 薬学部, 教授
1986: Faculty of Pharmaceutical Sciences, Nagoya City University, 薬学部, 教授
Review Section/Research Field
Principal Investigator
Chemical pharmacy / General internal medicine (including Psychosomatic medicine)
Except Principal Investigator
Biological pharmacy / Environmental pharmacy / Chemical pharmacy / General internal medicine (including Psychosomatic medicine)
Keywords
Principal Investigator
saikosaponin d / saikosaponin c / saikosaponin a / Histone H3 / Peptidyl-prolyl cis-trans isomerase / FK506 binding protein 12 / T.vivax(IL1392) / Gallic acid / Trypanosoma / コルチコステロン … More / 漢方方剤 / hemolysis / corticosterone-secretion / cleavage of glycosidic bond / alcoholic alkali metal / 20(S)ーginsenosideーRg_2 / 細胞膜への吸着 / 赤血球溶血態 / 消化管内代謝物 / 赤血球膜への吸着 / 赤血球溶血 / コルチコステロン分泌活性 / Saikosoporin d / Saikosoporin c / Saikosaponin a / 糖鎖切断反応 / アルコール性アルカリ金属 / corticosterone / pituitary - adrenocortical axis function / structure-activity relationship / intestinal flora / アルカリ反解反応 / 下垂体-副腎系刺激作用 / 構造活性相関 / 腸内細菌 / サイコサポニンc / サイコサポニンd / サイコサポニンa / regulatory T cell / 2.4.6-trinitrochlorobenzene / NC mice / Juzen-taiho-to / Kampo medicine / atopic dermatitis / トランスクリプトーム解析 / 2,4,6-trinitrochlorobenzne / ハプテン / 制御性T細胞 / 2,4,6-trinitrochlorobenzene / NCマウス / 十全大補湯 / アトピー性皮膚炎 / Selectivity / Apoptosis / Zephyranthes alkaloids / Gallic Acid / 活性酸素 / カルシウム / 細胞死 / 没食子酸誘導体 / FK506 binding protein12 / 選択性 / アポトーシス / ヒガンバナアルカロイド / 没食子酸 / Cytotoxic activity / Anti-Trypanosoma activity / T.bruci gambiense(Wellcome Strain / 走化反応 / 花粉 / Fuchsia hybrida / 細胞致死活性 / 抗トリパノソーマ活性 / T.bruci gambiense(Wellcome株) / T.ivirax(IL1392) / Phagocytosis / Hemolytic action / Saikosaponin / Interleukin-1 / Macrophage / Daisaikoto / Shosaikoto / Kampo prescription / 薬理作用 / サポニン / 大柴胡夜 / 生薬配合 / 複合成分 / グリチルリチン / 貧食能 / 溶血 / サイコサポニン / インタ-ロイキンー1 / マクロファ-ジ / 大柴胡湯 / 小柴胡湯 / BeWo cell / Isoelectrie focusing / Amino and sequence / Antiーtumor protein / Abortifacient protein / Trichosanthes kirilowii var,japonicum / Karasurin / Plant protein / 毛状根培養 / 土壌細菌 / タンパク質多型 / 抗腫瘍活性 / アミノ酸配列 / 堕胎薬 / カラスリン / キカラスウリ … More
Except Principal Investigator
Aquilaria / Cinnamomum / RFLP / 漢方薬 / medicinal plants / incense / field work / agarwood / cinnamon / Vietnam / 薬用植物 / 薫香料 / フィールドワーク / 沈香 / 桂皮 / ベトナム / Endothelial cell / Macrophage / Hydrogen peroxide / Phenylethanoid glycoside / Acteoside / シグナル伝達 / ICAM-1 / IL-6 / IL-1β / TNF-α / 内皮細胞 / マクロファージ / 過酸化水素 / フェニルエタノイド配糖体 / アクテオシド / Classification / Breeding / Biological activity / Tissue culture / Cultivation / Evaluation / Chinese medicinal plants / 成分 / 培養 / 漢薬資源植物 / 分類 / 繁殖 / 生物活性 / 組織培養 / 栽培 / 品質評価 / 漢薬資源 / 網羅的遺伝子発現解析 / SAGE法 / 網羅的遺伝子発現 / 薬物代謝酵素 / 薬物相互作用 / 民族伝統薬物 Less
  • Research Projects

    (12 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (25 People)
  •  漢方薬と西洋薬の相互作用をゲノムワイドに探る

    • Principal Investigator
      水上 元
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Nagoya City University
  •  Basic and clinical evaluation of Juzen-taiho-to usedin atopic dermatitisPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Meijo University
  •  Study on the production of medicinal plants characteristic of Vietnam based on the field work.

    • Principal Investigator
      HONDA Gisho
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for University and Society Collaboration
    • Research Field
      Environmental pharmacy
    • Research Institution
      KYOTO UNIVERSITY
  •  Investigation of natural products with selective cytotoxicity against tumor cellsPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  Phenylethanoid glycosides as a new macrophage-activating factor

    • Principal Investigator
      INOUE Makoto
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University
  •  植物タンパクの医薬品への応用開発Principal Investigator

    • Principal Investigator
      荻原 幸夫
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  漢方薬を中心とした民族伝統薬物の先端技術による医薬学的解明と科学的確立

    • Principal Investigator
      菊池 徹
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  The chemical attractant against T.virax from pollen grainsPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya City University
  •  EVALUATION AND DEVELOPMENT OF CHINESE MEDICINAL PLANTS.

    • Principal Investigator
      NAKAJIMA Terumi
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Significance of Crude Drug Composition and Plural Components in Kampo Prescription.Principal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  Cleavage of glycosidic bond in alcoholic alkali metal solutionPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  Structural transformation of saikosaponins by intestinal flora and structure - activity relationship between their derivatives in anti - inflammatory actionPrincipal Investigator

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University

All 2005 2003

All Journal Article

  • [Journal Article] Dermal mast cells play a central role on the incidence of scratching behavior in mice induced by multiple application of the hapten, 2,4,6-trinitrochlorobenzene2005

    • Author(s)
      H.Yamashita, Y.Michibata, H.Mizukami, Y.Ogihara, A.Morita, M.Nose
    • Journal Title

      Experimental Dermatology 14・2

      Pages: 438-444

    • Data Source
      KAKENHI-PROJECT-16659175
  • [Journal Article] Sho-saiko-to and Saiko-keishi-to, the traditional Chinese and Japanese herbal medicines, altered hepatic drug-metabolizing enzymes in mice and rats when administered orally for long time2003

    • Author(s)
      Nose, M., Tamura, M., Ryu, N., Mizukami, H., Ogihara, Y.
    • Journal Title

      Journal of Pharmacy and Pharmacology 50

      Pages: 1419-1426

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590607
  • 1.  NOSE Mituhiko (60228327)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 2.  INOUE Makoto (50191888)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  TAKEDA Tadahiro (90106253)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  AMAGAYA Sakae (80137124)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  YABU Yoshisada (70080083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NAKAJIMA Terumi (50012597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  NOHARA Toshihiro (30037600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YOSHIDA Takashi (20025696)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TSUDA Yoshisuke (40077508)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MURAKOSHI Isamu (30009162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  UENO Akira (30046247)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KOJIMA Keisuke (40275144)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HONDA Gisho (00093310)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ITO Michiho (30283592)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KIUCHI Fumiyuki (60161402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  菊池 徹 (40025680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  渡辺 裕司 (10012642)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  渡辺 和夫 (80019124)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  野村 靖幸 (00034041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  木村 正康 (60019099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  水上 元 (30128219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  田端 守 (60025682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  奥田 拓男 (90025677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  HIRUMI Hiroyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SHIMADA Yasuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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