SHINOTOH HITOSHI 篠遠仁

Researcher Number	10178882
Affiliation (based on the past Project Information) *help	2017: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所脳機能イメージング研究部, 上席研究員 2016 – 2017: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所脳機能イメージング研究部, 上席研究員(任非) 2015: 国立研究開発法人放射線医学総合研究所, 分子イメージング研究センター, 研究員 2014: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 研究員
Review Section/Research Field	Except Principal Investigator Neurology
Keywords	Except Principal Investigator PET / 進行性核上性麻痺 / タウ / タウオパチー / 神経機能画像学 / 大脳皮質基底核症候群 / Alzheimer病 / 重症度評価 / アルツハイマー病 / バイオマーカー … More / 認知症 / タウPET / 神経機能画像 / 糖代謝脳が俗 / ポジトロンCT / 脳機能画像 / 脳代謝 / 診断能 / ネットワーク解析 / 脳血流画像 / 脳糖代謝画像 / 大脳皮質基底核変性症 / ネットワーク / 脳血流 / FDG PET / 皮質基底核症候群 Less

Multimodal neuroimaging study in tauopathies.
- Principal Investigator
  
  Hirano Shigeki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Chiba University
Tau PET study for revealing the pathogenesis and establishing the objective marker of disease severity in neurodegenerative dementia
- Principal Investigator
  
  Shimada Hitoshi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology

All 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Tau-induced focal neurotoxicity and network disruption related to apathy in Alzheimer's disease2018
- Author(s)
  Soichiro Kitamura, Hitoshi Shimada*, Fumitoshi Niwa, Hironobu Endo, Hitoshi Shinotoh, Keisuke Takahata, Manabu Kubota, Yuhei Takado, Shigeki Hirano, Yasuyuki Kimura, Ming-Rong Zhang, Satoshi Kuwabara, Tetsuya Suhara, Makoto Higuchi
- Journal Title
  
  Journal of Neurology, Neurosurgery, and Psychiatry
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26713031
[Journal Article] Association between Aβ and tau accumulations and their influence on clinical features in aging and Alzheimer’s disease spectrum brains: A [11C]PBB3-PET study2017
- Author(s)
  Shimada H, Kitamura S, Shinoto H, Endo H, Niwa F, Hirano, S Zhang M-R, Suhara T, Higuchi M
- Journal Title
  
  Alzheimer’s & Dementia (Amst)
  
  Volume: 6 Issue: 1 Pages: 11-20
- DOI
  10.1016/j.dadm.2016.12.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-16H05324, KAKENHI-PROJECT-26713031
[Journal Article] A new method to quantify tau pathologies with 11C-PBB3 PET using reference tissue voxels extracted from brain cortical gray matter.2016
- Author(s)
  Kimura Y, Endo H, Ichise M, Shimada H, Seki C, Ikoma Y, Shinotoh H, Yamada M, Higuchi M, Zhang MR, Suhara T
- Journal Title
  
  EJNMMI Res
  
  Volume: 6 Issue: 1 Pages: 24-24
- DOI
  10.1186/s13550-016-0182-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23111009, KAKENHI-PROJECT-23390235, KAKENHI-PROJECT-26713031
[Journal Article] PET Quantification of Tau Pathology in Human Brain with 11C-PBB32015
- Author(s)
  Yasuyuki Kimura, Masanori Ichise, Hiroshi Ito, Hitoshi Shimada, Yoko Ikoma, Chie Seki, Harumasa Takano, Soichiro Kitamura, Hitoshi Shinotoh, Kazunori Kawamura, Ming-Rong Zhang, Naruhiko Sahara, Tetsuya Suhara, Makoto Higuchi
- Journal Title
  
  Journal of nuclear medicine
  
  Volume: 56 Issue: 9 Pages: 1359-1365
- DOI
  10.2967/jnumed.115.160127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06793, KAKENHI-PLANNED-23111009, KAKENHI-PROJECT-23390235, KAKENHI-PROJECT-25461862, KAKENHI-PROJECT-26713031, KAKENHI-PLANNED-26117008
[Presentation] PET quantification of binding of a novel tau radioligand, 18F-AM-PBB3, in consideration of time-dependent changes in its plasma free fraction.2017
- Author(s)
  北村　聡一郎, 木村　泰之, 市瀬　正則, 関　千江, 島田　斉, 篠遠　仁, ら.
- Organizer
  Brain and Brain PET 201
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Abnormal metabolic brain networks in progressive supranuclear palsy and corticobasal syndrome: Diagnostic performance using perfusion SPECT Scans In patients with movement disorders2017
- Author(s)
  Shigeki Hirano, Yilong Ma, Shichun Peng, Hitoshi Shimada, Hitoshi Shinotoh, Hironobu Endo, Yoshikazu Nakano, Hongliang Li, Makoto Higuchi, Satoshi Kuwabara,, David Eidelberg, Tetsuya Suhara
- Organizer
  23rd World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461307
[Presentation] Alzheimer病のアパシー症状とタウ病変の関連性 11C-PBB3 PET研究2017
- Author(s)
  北村　聡一郎, 島田　斉, 篠遠　仁, ら.
- Organizer
  第32会日本老年精神医学会
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Alzheimer病におけるアパシー症状とタウ病変の関係性2017
- Author(s)
  北村　聡一郎, 島田　斉, 篠遠　仁, 丹羽文俊, 遠藤浩信, 高畑　圭輔, 久保田　学, 高堂　裕平, 平野　成樹, 木村　泰之, 張　明栄, 桑原聡, 須原　哲也, 樋口　真人
- Organizer
  第56回千葉核医学研究会
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] 進行性核上性麻痺の脳機能ネットワーク障害パターンの確立2016
- Author(s)
  平野成樹、島田斉、篠遠仁、遠藤浩信、桑原聡、樋口真人、須原哲也
- Organizer
  第10回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都ホテルオークラ(京都府京都市)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461307
[Presentation] Quantification and reference optimization of tau PET imaging with [11C] PBB3 in PSP patients2016
- Author(s)
  Hitoshi Shimada , Yasuyuki Kimura , Masanori Ichise , Hiroshi Ito , Hironobu Endo , Keisuke Takahata , Fumitoshi Niwa , Soichiro Kitamura , Shigeki Hirano , Hitoshi Shinotoh , Naruhiko Sahara , Makiko Yamada , Ming-Rong Zhang , Makoto Higuchi , Tetsuya Suhara.
- Organizer
  10th Human Amyloid Imaging
- Place of Presentation
  Miami, USA
- Year and Date
  2016-01-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Brain metabolic correlates of pallidal tau in progressive supranuclear palsy.2015
- Author(s)
  Shogo Furukawa, Shigeki Hirano, Hitoshi Shimada, Hitoshi Shinotoh, Naruhiko Sahara, Hironobu Endo1 Soichiro Kitamura, Fumitoshi Niwa, Keisuke Takahata, Yasuyuki Kimura, Makiko Yamada, Ming-rong Zhang, Hiroshi Ito, Makoto Higuchi, Satoshi Kuwabara, Tetsuya Suhara
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟県新潟市新潟コンベンションセンター
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26461307
[Presentation] 高血圧症はアルツハイマー型認知症のタウ蓄積に寄与するか？～PET画像を用いた検討2015
- Author(s)
  丹羽　文俊 , 島田　斉 , 篠遠　仁 , 遠藤　浩信 , 北村　聡一郎 , 平野　成樹 , 古川　彰吾 , 樋口　真人 , 須原　哲也.
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ(新潟コンベンションセンター)
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] [11C]PBB3 PETによるMAPT遺伝子変異症例のタウイメージング2015
- Author(s)
  篠遠　仁 , 佐原　成彦 , 島田　斉 , Wszorek, Z. , 池内　健 , 羽生　春夫 , 石井　賢二 , 樋口　真人 , 須原　哲也
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーションホール青森、ホテル青森
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Brain metabolic correlates of tau accumulation in progressive supranuclear palsy2015
- Author(s)
  Shogo Furukawa , Shigeki Hirano , Hitoshi Shimada , Hitoshi Shinotoh , Naruhiko Sahara , Hironobu Endo , Soichiro Kitamura , Fumitoshi Niwa , Keisuke Takahata , Yasuyuki Kimura , Makiko Yamada , Ming-Rong Zhang , Hiroshi Ito , Makoto Higuchi , Satoshi Kuwabara , Tetsuya Suhara
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ(新潟コンベンションセンター)
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Progressive supranuclear palsy患者における臨床症候と[11C]-PBB3 PET集積の関係2015
- Author(s)
  遠藤　浩信 , 島田　斉 , 篠遠　仁 , 丹羽　文俊 , 北村　聡一郎 , 平野　成樹 , 古川　彰吾 , 樋口　真人 , 須原　哲也
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ(新潟コンベンションセンター)
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Parametric visualisation and quantification of tau pathology in human brain using PET with [C-11]PBB32015
- Author(s)
  木村　泰之 , 市瀬　正則 , 生駒　洋子 , 島田　斉 , 関　千江 , 北村　聡一郎 , 篠遠　仁 , 伊藤　浩 , 須原　哲也 , 樋口　真人.
- Organizer
  Society of Nuclear Medicine and Molecular Imaging annual meeting 2015
- Place of Presentation
  Baltimore, MD, USA
- Year and Date
  2015-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] 11C-PBB3を用いたタウ病変のPET定量解析2015
- Author(s)
  木村　泰之 , 市瀬　正則 , 伊藤　浩 , 島田　斉 , 生駒　洋子 , 関　千江 , 高野　晴成 , 北村　聡一郎 , 篠遠　仁 , 須原　哲也 , 樋口　真人.
- Organizer
  第55回日本核医学会学術総会
- Place of Presentation
  ハイアットリージェンシー東京
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Recent advances in clinical tau PET imaging with [11C]PBB32015
- Author(s)
  島田　斉 , 篠遠　仁 , 遠藤　浩信 , 古賀　俊介 , 北村　聡一郎 , 丹羽　文俊 , 石川　愛 , 平野　成樹 , 木村　泰之 , 市瀬　正則 , 山田　真希子 , 佐原　成彦 , 樋口　真人 , 須原　哲也.
- Organizer
  千葉大神経内科教室例会
- Place of Presentation
  オークラ千葉ホテル
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Clinical significance of tau accumulation assessed by [11C]PBB3 PET in diverse tauopathies2015
- Author(s)
  島田　斉 , 須原　哲也 , 篠遠　仁 , 平野　成樹 , 山田　真希子 , 木村　泰之 , 佐原　成彦 , 張　明栄 , 伊藤　浩 , 樋口　真人 , 桑原　聡.
- Organizer
  2015 World Molecular Imaging Congress
- Place of Presentation
  Hawaii Convention Center
- Year and Date
  2015-09-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Diagnostic utility and clinical significance of tau PET imaging with 11C-PBB32015
- Author(s)
  Hitoshi Shimada , Hitoshi Shinotoh , Naruhiko Sahara , Shigeki Hirano , Shogo Furukawa , Hironobu Endo , Soichiro Kitamura , Fumitoshi Niwa , Keisuke Takahata , Yasuyuki Kimura , Makiko Yamada , Yasumasa Yoshiyama , Ming-Rong Zhang , Hiroshi Ito , Makoto Higuchi , Satoshi Kuwabara , Tetsuya Suhara
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター
- Year and Date
  2015-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Tau accumulation in patients with MAPT gene mutation measured by [11C]PBB3 PET.2015
- Author(s)
  Hitoshi Shinotoh , Hitoshi Shimada , Wszolek Zbigniew , Takeshi Ikeuchi , Fumitoshi Niwa , Hironobu Endo , Soichiro Kitamura , Shigeki Hirano , Shunsuke Koga , Naruhiko Sahara , Dickson Dennis , Makoto Higuchi , Tetsuya Suhara.
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ(新潟コンベンションセンター)
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26713031
[Presentation] Brain metabolic correlates of cortical tau in progressive supranuclear palsy.A [11C]PBB3 and [18F]FDG PET study.
- Author(s)
  Shogo Furukawa, Shigeki Hirano, Hitoshi Shimada，Hitoshi Shinotoh， Naruhiko Sahara, Hironobu Endo， Soichiro Kitamura， Fumitoshi Niwa， Keisuke Takahata， Yasuyuki Kimura, Makiko Yamada，Ming-rong Zhang， Hiroshi Ito， Makoto Higuchi，Satoshi Kuwabara, Tetsuya Suhara
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟コンベンションセンター（新潟県新潟市）
- Year and Date
  2015-05-20 – 2015-05-23
- Data Source
  KAKENHI-PROJECT-26461307

1. Hirano Shigeki (60375756)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. Shimada Hitoshi (10422239)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
3. HIGUCHI MAKOTO (10373359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
4. SUHARA TETSUYA (90216490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. KIMURA YASUYUKI (20423171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. KITAMURA SOICHIRO (10714389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
7. 古川彰吾 (00722943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐原成彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHINOTOH HITOSHI 篠遠 仁

Research Projects

Research Products

Co-Researchers

Multimodal neuroimaging study in tauopathies.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Tau PET study for revealing the pathogenesis and establishing the objective marker of disease severity in neurodegenerative dementia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Tau-induced focal neurotoxicity and network disruption related to apathy in Alzheimer's disease2018

Author(s)

Journal Title

Data Source

[Journal Article] Association between Aβ and tau accumulations and their influence on clinical features in aging and Alzheimer’s disease spectrum brains: A [11C]PBB3-PET study2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A new method to quantify tau pathologies with 11C-PBB3 PET using reference tissue voxels extracted from brain cortical gray matter.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PET Quantification of Tau Pathology in Human Brain with 11C-PBB32015

Author(s)

Journal Title

DOI

Data Source

[Presentation] PET quantification of binding of a novel tau radioligand, 18F-AM-PBB3, in consideration of time-dependent changes in its plasma free fraction.2017

Author(s)

Organizer

Data Source

[Presentation] Abnormal metabolic brain networks in progressive supranuclear palsy and corticobasal syndrome: Diagnostic performance using perfusion SPECT Scans In patients with movement disorders2017

Author(s)

Organizer

Data Source

[Presentation] Alzheimer病のアパシー症状とタウ病変の関連性 11C-PBB3 PET研究2017

Author(s)

Organizer

Data Source

[Presentation] Alzheimer病における アパシー症状とタウ病変の関係性2017

Author(s)

Organizer

Data Source

[Presentation] 進行性核上性麻痺の脳機能ネットワーク障害パターンの確立2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Quantification and reference optimization of tau PET imaging with [11C] PBB3 in PSP patients2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Brain metabolic correlates of pallidal tau in progressive supranuclear palsy.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 高血圧症はアルツハイマー型認知症のタウ蓄積に寄与するか？～PET画像を用いた検討2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] [11C]PBB3 PETによるMAPT遺伝子変異症例のタウイメージング2015

Author(s)

Organizer

Place of Presentation

Year and Date

SHINOTOH HITOSHI 篠遠仁

[Presentation] Alzheimer病におけるアパシー症状とタウ病変の関係性2017