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Kimura Yasuyuki  木村 泰之

… Alternative Names

KIMURA Yasuyuki  木村 泰之

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Researcher Number 20423171
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-7927-9483
Affiliation (Current) 2022: 国立研究開発法人国立長寿医療研究センター, 研究所 認知症先進医療開発センター, 副部長
Affiliation (based on the past Project Information) *help 2021 – 2022: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 副部長
2017 – 2020: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 室長
2016 – 2017: 国立研究開発法人国立長寿医療研究センター, 脳機能画像診断開発部, 室長
2015: 国立研究開発法人放射線医学総合研究所, 分子イメージング研究センター, 主任研究員
2014: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 主任研究員
2012 – 2013: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 研究員
Review Section/Research Field
Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related / Medium-sized Section 52:General internal medicine and related fields
Except Principal Investigator
Basic Section 52030:Psychiatry-related / Radiation science / Neurology / Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 52010:General internal medicine-related
Keywords
Principal Investigator
PET / 陽電子断層撮像法 / アルツハイマー病 / CSF1R / ミクログリア / 代謝型グルタミン酸受容体サブタイプ 5 / ポジトロンエミッショントモグラフィー / reproducibility / 代謝型グルタミン酸受容体サブタイプ5 / mGluR5 … More / ドーパミントランスポーター / AMPA受容体 / 陽電子断層撮影法 / 陽電子射出断層撮影 / 陽電子断層撮像 / マイクログリア / 神経炎症 / microglia / Alzheimer's disease / 生体直交反応 / IEDDA / 神経変性疾患 … More
Except Principal Investigator
PET / アルツハイマー病 / バイオマーカー / 11C標識分子プローブ / アルツハイマー型認知症 / イソプロテレノール / マイクロドーズ試験 / 陽電子断層撮像法 / アルツハイマー / タウ蛋白 / 被曝線量 / MIRD法 / 神経機能画像 / タウPET / 認知症 / タウオパチー / 進行性核上性麻痺 / 重症度評価 / Alzheimer病 / 大脳皮質基底核症候群 / 神経機能画像学 / タウ / O6-メチルグアニン-DNA-トランスフェラーゼ / O6-ベンジルグアニン / 遺伝子変異イソクエン酸脱水素酵素1 / α-ケトグルタル酸 / 脳内神経炎症 / ポジトロンCT / トランスロケーター蛋白 / 認知症行動心理症状 / 血液バイオマーカー / PET炎症イメージング / トランスロケーター蛋白(TSPO) / 炎症イメージング / グリア細胞 / 非環式レチノイド(ペレチノイン) / 高速クロスカップリング / 11C標識 / 脳イメージング / 血液脳関門透過性 / 非環式レチノイド / PET脳イメージング / 高い血液脳関門透過性 / 核内受容体 / 非環式レチノイド(4,5-ジデヒドロGGA) / PETイメージング / プロドラッグ / 脳内移行性 / システマティックレビュー / 炎症系サイトカイン / 全身性炎症 / 精神行動症状 Less
  • Research Projects

    (12 results)
  • Research Products

    (45 results)
  • Co-Researchers

    (44 People)
  •  アルツハイマー病前臨床期の血液およびPETバイオマーカーの有用性に関する調査研究

    • Principal Investigator
      二橋 尚志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  The research of the systemic inflammation as a cause of neuropsychiatric symptoms in Alzheimer's disease

    • Principal Investigator
      安野 史彦
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  Development of PET imaging of brain immunity as a biomarker for drug development to treat neurodegenerative diseasesPrincipal Investigator

    • Principal Investigator
      木村 泰之
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  Development of brain PET imaging using bioorthogonal reactionsPrincipal Investigator

    • Principal Investigator
      木村 泰之
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  特異的発現酵素を標的とした脳腫瘍イメージングPETプローブの斬新化

    • Principal Investigator
      鈴木 正昭
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 37:Biomolecular chemistry and related fields
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  In vivo investigation of neuroinflammation of AD with PET molecular imaging

    • Principal Investigator
      Yasuno Fumihiko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  PET imaging of microglia, a novel drug target for neurodegenerative diseasesPrincipal Investigator

    • Principal Investigator
      Kimura Yasuyuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  Synthesis of 11C-labeled acyclic retinoids with high brain permeability

    • Principal Investigator
      Koyama Hiroko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Gifu University
  •  PET microdose study for finding appropriate dose of isoproterenol as a disease modifying treatment of dementia

    • Principal Investigator
      Ito Kengo
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  Quantitative PET imaging of AMPA receptors in humansPrincipal Investigator

    • Principal Investigator
      KIMURA Yasuyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Center for Geriatrics and Gerontology
      National Institute of Radiological Sciences
  •  Tau PET study for revealing the pathogenesis and establishing the objective marker of disease severity in neurodegenerative dementia

    • Principal Investigator
      Shimada Hitoshi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Neurology
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  PET measurements of interaction between glutamatergic and dopaminergic neuronsPrincipal Investigator

    • Principal Investigator
      KIMURA Yasuyuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      National Institute of Radiological Sciences

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

  • [Journal Article] Kinetic modeling and non-invasive approach for translocator protein quantification with 11C-DPA-713.2022

    • Author(s)
      Yasuno F, Kimura Y, Ogata A, Ikenuma H, Abe J, Minami H, Nihashi T, Yokoi K, Hattori S, Shimoda N, Ichise M, Sakurai T, Ito K, Kato T.
    • Journal Title

      Nucl Med Biol

      Volume: 108 Pages: 76-84

    • DOI

      10.1016/j.nucmedbio.2022.02.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03590
  • [Journal Article] [11C]NCGG401, a novel PET ligand for imaging of colony stimulating factor 1 receptors2022

    • Author(s)
      Ogata Aya、Ji Bin、Yamada Takashi、Hattori Saori、Abe Junichiro、Ikenuma Hiroshi、Ichise Masanori、Koyama Hiroko、Suzuki Masaaki、Kato Takashi、Ito Kengo、Kimura Yasuyuki
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 65 Pages: 128704-128704

    • DOI

      10.1016/j.bmcl.2022.128704

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02876
  • [Journal Article] Brain pharmacokinetics and biodistribution of 11C-labeled isoproterenol in rodents2020

    • Author(s)
      Ogata Aya、Kimura Yasuyuki、Ikenuma Hiroshi、Yamada Takashi、Abe Junichiro、Koyama Hiroko、Suzuki Masaaki、Ichise Masanori、Kato Takashi、Ito Kengo
    • Journal Title

      Nucl. Med. Biol.

      Volume: - Pages: 52-58

    • DOI

      10.1016/j.nucmedbio.2020.06.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04269, KAKENHI-PROJECT-18K06575
  • [Journal Article] First prototyping of a dedicated PET system with the hemisphere detector arrangement.2019

    • Author(s)
      Hideaki Tashima, Eiji Yoshida, Yuma Iwao, Hidekatsu Wakizaka, Takamasa Maeda, Chie Seki, Yasuyuki Kimura, Yuhei Takado, Makoto Higuchi, Tetsuya Suhara, Taichi Yamashita, Taiga Yamaya
    • Journal Title

      Phys Med Biol.

      Volume: 64 Issue: 6 Pages: 065004-065004

    • DOI

      10.1088/1361-6560/ab012c

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05324, KAKENHI-PROJECT-16K21637, KAKENHI-PROJECT-15K21774, KAKENHI-PROJECT-18K06575
  • [Journal Article] 22.Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11C]acetone2019

    • Author(s)
      Ikenuma Hiroshi、Koyama Hiroko、Kajino Naoya、Kimura Yasuyuki、Ogata Aya、Abe Junichiro、Kawasumi Yasuhiro、Kato Takashi、Takashima Akihiko、Ito Kengo、Suzuki Masaaki
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 29 Pages: 2107-2111

    • DOI

      10.1016/j.bmcl.2019.07.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04269, KAKENHI-PROJECT-18K06575
  • [Journal Article] Tau imaging detects distinctive distribution of tau pathology in ALS/PDC on the Kii Peninsula.2019

    • Author(s)
      Shinotoh Hitoshi、Shimada Hitoshi、Kokubo Yasumasa、Tagai Kenji、Niwa Fumitoshi、Kitamura Soichiro、Endo Hironobu、Ono Maiko、Kimura Yasuyuki、Hirano Shigeki、Mimuro Maya、Ichise Masanori、Sahara Naruhiko、Zhang Ming-Rong、Suhara Tetsuya、Higuchi Makoto
    • Journal Title

      Neurology.

      Volume: 92

    • DOI

      10.1212/wnl.0000000000006736

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07368, KAKENHI-PROJECT-18KK0239, KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-17H01689, KAKENHI-PROJECT-16H05324, KAKENHI-PROJECT-15K09364, KAKENHI-PROJECT-16K19872, KAKENHI-PROJECT-18K06575
  • [Journal Article] Tau-induced focal neurotoxicity and network disruption related to apathy in Alzheimer's disease2018

    • Author(s)
      Soichiro Kitamura, Hitoshi Shimada*, Fumitoshi Niwa, Hironobu Endo, Hitoshi Shinotoh, Keisuke Takahata, Manabu Kubota, Yuhei Takado, Shigeki Hirano, Yasuyuki Kimura, Ming-Rong Zhang, Satoshi Kuwabara, Tetsuya Suhara, Makoto Higuchi
    • Journal Title

      Journal of Neurology, Neurosurgery, and Psychiatry

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Journal Article] A human PET study of [11C]HMS011, a potential radioligand for AMPA receptors.2018

    • Author(s)
      Keisuke Takahata et al.,
    • Journal Title

      EJNMMI Research

      Volume: 16 Pages: 63-63

    • DOI

      10.1186/s13550-017-0313-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19789, KAKENHI-PROJECT-16K19790, KAKENHI-PROJECT-16H05324, KAKENHI-PROJECT-15K09977
  • [Journal Article] Association between Aβ and tau accumulations and their influence on clinical features in aging and Alzheimer's disease spectrum brains: A [11C]PBB3-PET study.2017

    • Author(s)
      Shimada H, Kitamura S, Shinoto H, Endo H, Niwa F, Hirano, S Zhang M-R, Suhara T, Higuchi M
    • Journal Title

      Alzheimers Dement (Amst)

      Volume: 6 Pages: 11-20

    • DOI

      10.1016/j.dadm.2016.12.009

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-16H05324, KAKENHI-PROJECT-26713031
  • [Journal Article] PET Quantification in Molecular Brain Imaging Taking into Account the Contribution of the Radiometabolite Entering the Brain2016

    • Author(s)
      Ichise M., Kimura Y., Shimada H., Higuchi M., Suhara T.
    • Journal Title

      Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy

      Volume: 1 Pages: 219-228

    • Open Access
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Journal Article] A new method to quantify tau pathologies with (11)C-PBB3 PET using reference tissue voxels extracted from brain cortical gray matter.2016

    • Author(s)
      Kimura Y, Endo H, Ichise M, Shimada H, Seki C, Ikoma Y, Shinotoh H, Yamada M, Higuchi M, Zhang MR, Suhara T
    • Journal Title

      EJNMMI Res.

      Volume: 6 Pages: 24-24

    • DOI

      10.1186/s13550-016-0182-y

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23111009, KAKENHI-PROJECT-23390235, KAKENHI-PROJECT-26713031
  • [Journal Article] PET Quantification of Tau Pathology in Human Brain with 11C-PBB3.2015

    • Author(s)
      Yasuyuki Kimura, Masanori Ichise, Hiroshi Ito, Hitoshi Shimada, Yoko Ikoma, Chie Seki, Harumasa Takano, Soichiro Kitamura, Hitoshi Shinotoh, Kazunori Kawamura, Ming-Rong Zhang, Naruhiko Sahara, Tetsuya Suhara, Makoto Higuchi
    • Journal Title

      Journal of Nuclear Medicine

      Volume: 56 Pages: 1359-1365

    • DOI

      10.2967/jnumed.115.160127

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K06793, KAKENHI-PLANNED-23111009, KAKENHI-PROJECT-23390235, KAKENHI-PROJECT-25461862, KAKENHI-PROJECT-26713031, KAKENHI-PLANNED-26117008
  • [Patent] 1.[11C]標識非環式レチノイド、中枢神経系活性化剤及びそれらの製造方法2020

    • Inventor(s)
      鈴木 正昭、伊藤 健吾、木村 泰之、古山 浩子、他
    • Industrial Property Rights Holder
      鈴木 正昭、伊藤 健吾、木村 泰之、古山 浩子、他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-18K06575
  • [Presentation] PET imaging of [11C]NCGG401 for colony stimulating factor 1 receptor2021

    • Author(s)
      Ogata A, Yamada T, Abe J, Ichise M, Ikenuma H, Koyama H, Suzuki M, Kato T, Ito K, Kimura Y
    • Organizer
      NRM 2021 MAPPING NEURORECEPTORS AT WORK
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02876
  • [Presentation] RIPK1を標的とした新規PETリガンド開発の試みと有効性の評価2021

    • Author(s)
      池沼 宏、古山浩子、小懸綾、季斌、山田貴史、永井裕司、阿部潤一郎、市瀬正則、加藤隆司、鈴木正昭、木村泰之
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02876
  • [Presentation] Development of novel PET ligands to image the Receptor Interacting Protein Kinase 12021

    • Author(s)
      Sakai T, Yamada T, Ikenuma H, Ogata A, Ichise M, Hattori S, Abe J, Suzuki M, Ito K, Kato T, Imamura S, Kimura Y
    • Organizer
      NRM 2021 MAPPING NEURORECEPTORS AT WORK
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02876
  • [Presentation] Development of a novel PET ligand for receptor-interacting protein kinase 1 in brain2021

    • Author(s)
      Ikenuma H, Ogata A, Koyama H, Yamada T, Abe J, Ichise M, Kato T, Suzuki M, Ito K, Kimura Y
    • Organizer
      NRM 2021 MAPPING NEURORECEPTORS AT WORK
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02876
  • [Presentation] In vitro脳内出血病理モデルに対するレチノイドの組織保護効果2021

    • Author(s)
      中西咲乃,倉内祐樹,関貴弘,木村泰之,鈴木正昭,鈴木恵一,古山浩子,香月博志
    • Organizer
      第141年会日本薬学会
    • Data Source
      KAKENHI-PROJECT-18K06575
  • [Presentation] PET Imaging in Drug Development for Neurodegenerative Diseases.2020

    • Author(s)
      Kimura Y
    • Organizer
      The 14th International Conference on Complex Medical and Engineering
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02776
  • [Presentation] Improved (R,S)-[11C]isoproterenol formulation toward clinical study2019

    • Author(s)
      Hiroshi Ikenuma, Hiroko Koyama, Yasuyuki Kimura, Junichiro Abe, Yasuhiro Kawasumi, Aya Ogata, Takashi Yamada, Takashi Kato, Kengo Ito, Masaaki Suzuki
    • Organizer
      The 59th Annual Scientific Meeting of the Japanese Society of Nuclear Medicine
    • Data Source
      KAKENHI-PROJECT-18K06575
  • [Presentation] PET imaging of colony stimulating factor 1 receptor in rat brains2019

    • Author(s)
      A. Ogata,Y. Kimura, T. Yamada, M. Ichise, H. Ikenuma, J, Abe, H. Koyama, M. Suzuki, T. Kato, K. Ito
    • Organizer
      Brain & Brain PET 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06575
  • [Presentation] PET imaging of colony stimulating factor 1 receptor in rat brains.2019

    • Author(s)
      Ogata A, Kimura Y, Yamada T, Ichise M, Ikenuma H, Abe J, Koyama H, Suzuki M, Kato T, Ito K.
    • Organizer
      Brain & Brain PET 2019,
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02776
  • [Presentation] PET imaging of colony stimulating factor 1 receptor2019

    • Author(s)
      Aya Ogata, Yasuyuki Kimura, Takashi Yamada, Masanori Ichise, Junichiro Abe, Hiroshi Ikenuma, Hiroko Koyama, Masaaki Suzuki, Takashi Kato, and Kengo Ito
    • Organizer
      The 59th Annual Scientific Meeting of the Japanese Society of Nuclear Medicine
    • Data Source
      KAKENHI-PROJECT-18K06575
  • [Presentation] Colony stimulating factor 1 receptorを標的としたミクログリア特異的PETイメージングの開発2019

    • Author(s)
      小縣綾、木村泰之、山田貴史、市瀬正則、阿部潤一郎、池沼宏、古山浩子、鈴木正昭、加藤隆司、伊藤健吾
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02776
  • [Presentation] Formulation of 11C-labeled (R,S)-isoproterenol and pharmacokinetic studies in rats2019

    • Author(s)
      Hiroshi Ikenuma, Aya Ogata, Yasuyuki Kimura, Hiroko Koyama, Junichiro Abe, Takashi Yamada, Masanori Ichise, Takashi Kato, Masaaki Suzuki, and Kengo Ito
    • Organizer
      Brain & Brain PET 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06575
  • [Presentation] Formulation of 11C-labeled (R,S)-isoproterenol and pharmacokinetic studies in rats.2019

    • Author(s)
      Ikenuma H, Ogata A, Kimura Y, Koyama H, Abe J, Yamada T, Ichise M, Kato T, Suzuki M, Ito K
    • Organizer
      Brain & Brain PET 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04269
  • [Presentation] Improved (R,S)-[11C]isoproterenol formulation toward clinical study2019

    • Author(s)
      池沼宏、古山浩子、木村泰之、阿部潤一郎、川角保広、小縣綾、山田貴史、加藤隆司、伊藤健吾、鈴木正昭
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04269
  • [Presentation] 脳移行性グルコース・ギンゴライド連結体の設計とPETプローブ化2019

    • Author(s)
      鈴木 恵一,古山 浩子,池沼 宏,沢田 知辰,石井 里咲,石井 英樹,土居 久志,木村 泰之,鈴木 正昭
    • Organizer
      第50回中部化学関係学協会支部連合秋季大会
    • Data Source
      KAKENHI-PROJECT-18K06575
  • [Presentation] Synthesis of 11C-Labeled (R,S)-Isoproterenol and Preclinical PET Study2018

    • Author(s)
      Ikenuma H, Koyama H, Kajino N, Kimura Y, Ogata A, Abe J, Kawasumi Y, Kato T, Suzuki M, Ito K
    • Organizer
      The World Molecular Imaging Congress 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04269
  • [Presentation] Development of PET imaging of Colony Stimulating Factor 1 Receptor Expressed on Microglia.2018

    • Author(s)
      Ogata A, Kimura Y, Yamada T, Bin Ji, Seki C, Ichise M, Abe J, Ikenuma H, Koyama H, Suzuki M, Kato T, Ito K
    • Organizer
      The XII International Symposium of Functional Neuroreceptor Mapping of the Living Brain
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02776
  • [Presentation] The evaluation of a novel PET ligand for colony stimulating factor 1 receptor in status epilepticus model rat brains.2018

    • Author(s)
      Ogata A, Kimura Y, Yamada T, Bin Ji, Seki C, Ichise M, Abe J, Ikenuma H, Koyama H, Suzuki M, Kato T, Ito K
    • Organizer
      nnual Congress of the European Association of Nuclear Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02776
  • [Presentation] PET quantification of binding of a novel tau radioligand, 18F-AM-PBB3, in consideration of time-dependent changes in its plasma free fraction.2017

    • Author(s)
      北村 聡一郎, 木村 泰之, 市瀬 正則, 関 千江, 島田 斉, 篠遠 仁, ら.
    • Organizer
      Brain and Brain PET 201
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Presentation] Synthesis of highly-qualified 11C-labeled (R,S)-isoproterenol aimed at a clinical study2017

    • Author(s)
      Ikenuma H, Koyama H, Kimura Y, Abe J, Kawasumi K, Ogata A, Kato T, Ito K, Suzuki M.
    • Organizer
      The 12th Asia Oceania Congress of Nuclear Medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04269
  • [Presentation] 臨床研究を目的とした11C標識化(R,S)-イソプロテレノールの高効率合成法の開発2017

    • Author(s)
      池沼 宏、古山浩子、木村泰之、阿部潤一郎、川角保広、小縣 綾、加藤隆司、伊藤健吾、鈴木正昭
    • Organizer
      第57回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04269
  • [Presentation] A human PET study of [11C]HMS011, a potential radioligand for AMPA receptors2017

    • Author(s)
      Keisuke Takahata, Yasuyuki Kimura, Chie Seki, Masanori Ichise, Kazunori Kawamura, Soichiro Kitamura, Manabu Kubota, Sho Moriguchi, Tatsuya Ishi, Yuhei Takado, Fumitoshi Niwa, Hironobu Endo, Tomohisa Nagashima, Ming-Rong Zhang, Tetsuya Suhara, and Makoto Higuchi
    • Organizer
      Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09977
  • [Presentation] 認知症治療薬としてのイソプロテレノールの小動物PETを用いたラット脳内移行性の検討2017

    • Author(s)
      小縣 綾、木村泰之、池沼 宏、古山浩子、関千江、山田貴史、鈴木正昭、加藤隆司、伊藤健吾
    • Organizer
      第57回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04269
  • [Presentation] Alzheimer病における アパシー症状とタウ病変の関係性2017

    • Author(s)
      北村 聡一郎, 島田 斉, 篠遠 仁, 丹羽文俊, 遠藤浩信, 高畑 圭輔, 久保田 学, 高堂 裕平, 平野 成樹, 木村 泰之, 張 明栄, 桑原聡, 須原 哲也, 樋口 真人
    • Organizer
      第56回千葉核医学研究会
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Presentation] Brain penetration of isoproterenol as a drug of dementia measured in rats with a micro-PET2017

    • Author(s)
      Ogata A, Kimura Y, Ikenuma H, Koyama H, Seki C, Yamada T, Suzuki M, Kato T, Ito K.
    • Organizer
      The 12th Asia Oceania Congress of Nuclear Medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04269
  • [Presentation] Quantification and reference optimization of tau PET imaging with [11C] PBB3 in PSP patients2016

    • Author(s)
      Hitoshi Shimada , Yasuyuki Kimura , Masanori Ichise , Hiroshi Ito , Hironobu Endo , Keisuke Takahata , Fumitoshi Niwa , Soichiro Kitamura , Shigeki Hirano , Hitoshi Shinotoh , Naruhiko Sahara , Makiko Yamada , Ming-Rong Zhang , Makoto Higuchi , Tetsuya Suhara.
    • Organizer
      10th Human Amyloid Imaging
    • Place of Presentation
      Miami, USA
    • Year and Date
      2016-01-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Presentation] Brain metabolic correlates of tau accumulation in progressive supranuclear palsy2015

    • Author(s)
      Shogo Furukawa , Shigeki Hirano , Hitoshi Shimada , Hitoshi Shinotoh , Naruhiko Sahara , Hironobu Endo , Soichiro Kitamura , Fumitoshi Niwa , Keisuke Takahata , Yasuyuki Kimura , Makiko Yamada , Ming-Rong Zhang , Hiroshi Ito , Makoto Higuchi , Satoshi Kuwabara , Tetsuya Suhara
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟コンベンションセンター)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Presentation] Parametric visualisation and quantification of tau pathology in human brain using PET with [C-11]PBB32015

    • Author(s)
      木村 泰之 , 市瀬 正則 , 生駒 洋子 , 島田 斉 , 関 千江 , 北村 聡一郎 , 篠遠 仁 , 伊藤 浩 , 須原 哲也 , 樋口 真人.
    • Organizer
      Society of Nuclear Medicine and Molecular Imaging annual meeting 2015
    • Place of Presentation
      Baltimore, MD, USA
    • Year and Date
      2015-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Presentation] Recent advances in clinical tau PET imaging with [11C]PBB32015

    • Author(s)
      島田 斉 , 篠遠 仁 , 遠藤 浩信 , 古賀 俊介 , 北村 聡一郎 , 丹羽 文俊 , 石川 愛 , 平野 成樹 , 木村 泰之 , 市瀬 正則 , 山田 真希子 , 佐原 成彦 , 樋口 真人 , 須原 哲也.
    • Organizer
      千葉大神経内科教室例会
    • Place of Presentation
      オークラ千葉ホテル
    • Year and Date
      2015-12-12
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Presentation] Clinical significance of tau accumulation assessed by [11C]PBB3 PET in diverse tauopathies2015

    • Author(s)
      島田 斉 , 須原 哲也 , 篠遠 仁 , 平野 成樹 , 山田 真希子 , 木村 泰之 , 佐原 成彦 , 張 明栄 , 伊藤 浩 , 樋口 真人 , 桑原 聡.
    • Organizer
      2015 World Molecular Imaging Congress
    • Place of Presentation
      Hawaii Convention Center
    • Year and Date
      2015-09-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Presentation] Diagnostic utility and clinical significance of tau PET imaging with 11C-PBB32015

    • Author(s)
      Hitoshi Shimada , Hitoshi Shinotoh , Naruhiko Sahara , Shigeki Hirano , Shogo Furukawa , Hironobu Endo , Soichiro Kitamura , Fumitoshi Niwa , Keisuke Takahata , Yasuyuki Kimura , Makiko Yamada , Yasumasa Yoshiyama , Ming-Rong Zhang , Hiroshi Ito , Makoto Higuchi , Satoshi Kuwabara , Tetsuya Suhara
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ 新潟コンベンションセンター
    • Year and Date
      2015-05-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-26713031
  • [Presentation] 11C-PBB3を用いたタウ病変のPET定量解析2015

    • Author(s)
      木村 泰之 , 市瀬 正則 , 伊藤 浩 , 島田 斉 , 生駒 洋子 , 関 千江 , 高野 晴成 , 北村 聡一郎 , 篠遠 仁 , 須原 哲也 , 樋口 真人.
    • Organizer
      第55回日本核医学会学術総会
    • Place of Presentation
      ハイアットリージェンシー東京
    • Year and Date
      2015-11-05
    • Data Source
      KAKENHI-PROJECT-26713031
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