KOBAYASHI Shinjiro 古林伸二郎

… Alternative Names

KOBAYASHI Shinjiroh 古林伸二郎

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Researcher Number	10186744
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2004: HOKURIKU University, Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Professor, 薬学部, 教授 1998 – 2003: 北陸大学, 薬学部, 助教授 1987 – 1988: 富山医科薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy Except Principal Investigator General pharmacology
Keywords	Principal Investigator Nifedipine / 血管新生 / β-eudesmol / N^ε-(carboxymethyl)lysine / VEGF / Tetrandrine / 抗血管新生作用 / 血管内皮増殖因子 / Advanced Glycation End Product / Anti-angiogenic action … More / Neovascularization / Vascular endothelial progenitor cell / Age-related disease / Cultured choroidal explant / 2 / ERK 1 / CD34陽性内皮前駆細胞 / 血管内皮細胞 / N^ε-(Carboxymethyl)lysine (CML) / beta-eudesmol / 血管内皮前駆細胞 / 加齢関連疾患 / N^ε-(Carboxymethyl)lysine(CML) / 培養脈絡膜 / Tumor Necrosis Factor-alpha / Choroidal Capillary / Angiogenesis / THF-α / 糖尿病性網膜症 / 網膜 / Advanced Glycation Endproduct / 腫瘍懐死因子-alpha / Fangchinoline / 腫瘍壊死因子-alpha / 脈絡膜 / カルボキシメチルリジン / Advanced Glycation End Products / derivatives of tetrandrine / vascular endothelial growth factor / advanced glycation end product / anti CML antibody(6D12) / neovascularization / cultured retinal capillary / cultured choroidal capillary / diabetic retinopathy / テトランドリン関連化合物 / テトランドリン / 血管新生増強作用 / 糖尿病態 / 血管新生定量法 / 脈絡膜血管新生 / Vascular Endothelial Growth Factor / 血管新生因子遊離作用 / 抗CMI抗体(6D12) / N(ε)-(Carboxymethyl)lysine / Advanced Glycation Endproducts / 血管新生作用 / 培養脈絡膜組織 / 糖尿病生増殖型網膜症 / 加齢 / 血管新生因子 / テトランドリン誘導体 / 抗カルボキシメチル抗体(6D12) / 培養網膜血管組織 / 培養脈絡膜血管組織 / 糖尿病性増殖型網膜症 … More Except Principal Investigator diabetic state-induced modification of intracellular Ca^<2+> mobilization / potentiation mechanism of -eudesmol / site of action of succinylcholine / intracellular Ca^<2+> mobilization / muscle cell membrane / diabetic state / 筋Ca含有量 / 細胞膜の修飾 / 細胞内Ca / アセチルコリン受容体チャネルコンダクタンス / アセチルコリンエステレース阻害剤 / スクシニルコリン / Ca トランジェント / 筋細胞内の遊離Ca / β-ユーデスモール / パッチクランプ法 / Ca誘発脱感作 / 糖尿病態による細胞内Ca動員 / Bーユーデスモールの増強作用機序 / 新しいCaトランジェント成分 / スクシニルコリンの作用点 / 細胞内Ca動員 / 筋細胞膜 / 糖尿病態 / 糖尿病態細胞 / PGF_<2α>抑制作用 / エピネフリン抑制作用 / インスリン抑制作用 / 増殖抑制作用 / 培養血管平滑筋細胞 / 川〓成分 Less

Roles of AGE for neovascularization and proliferation of fibroblast-like cells in cultured rat choroidal explainsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Shinjiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKURIKU University
Roles of AGE for mechanism of angiogenesisPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Shinjiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokuriku University
Regulation of drugs on abnormal neovascularization of choroidal capillaries in diabetic ratsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Shinjiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokuriku University
糖尿病性血管平滑筋のインスリンによる培養細胞増殖機序とその抑制物質の研究
- Principal Investigator
  
  KIMURA Masayasu
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Toyama Medical and Pharmaceutical University
The mechanism of hypersensitization in diabetic state of neuromuscular synapse to depolarizing blockers
- Principal Investigator
  
  KIMURA Masayasu
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Toyama Medical & Pharmaceutical University

All 2005 2004

All Journal Article

[Journal Article] Inhibitory effect of nifedipine on tumor necrosis factor a-induced neovascularization in cultured choroidal explant of streptozotocin-diabetic rat2005
- Author(s)
  S Kobayashi, M Fukita, M Suzuki, H Tsuneki, I Kimura
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 242-246
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] Inhibitory effect of nifedipine on tumor necrosis factor a-induced neovascularization in cultured choroidal explants of streptozotocin-diabetic rat2005
- Author(s)
  S Kobayashi, M Fukuta, M Suzuki, H Tsuneki, I Kimura
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 242-246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] Antiangiogenic activity of beta-eudesmol in vitro and in vivo2005
- Author(s)
  H Tsuneki, E-L Ma, S Kobayashi, N Sekizaki, T Sasaoka, M-W Wang, I Kimura
- Journal Title
  
  Eur.J.Pharmacol. 512
  
  Pages: 105-115
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] A role of TNF-α for N^ε-(carboxymethyl)lysine-facilitated neovascularization of cultured choroidal explant in aged rat2005
- Author(s)
  S Kobayashi, M Suzuki, M Nomura, S Horiuchi, N Hagino
- Journal Title
  
  J.Pharm.Sci 97
  
  Pages: 187-187
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] Inhibitory effect of nifedipine on tumor necrosis factor α-induced neovascularization in cultured choroidal explants of streptozotocin-diabetic rat2005
- Author(s)
  S Kobayashi, M Fukita, M Suzuki, H Tsuneki, I Kimura
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 242-246
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] Antiangiogenic activity of beta-eudesmol in vitro and in vivo2005
- Author(s)
  H Tsuneki, E-L Ma, S Kobayashi, N Sekizaki, T Sasaoka, M-W Wang, I Kimura
- Journal Title
  
  Eur.J.Pharmacol. (In press)
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] A role of TNF-α for N^ε-(carboxymethyl)lysine-facilitated neovascularization of cultured choroidal explant in aged rat2005
- Author(s)
  S Kobayashi, M Suzuki, M Nomura, S Horiuchi, N Hagino
- Journal Title
  
  J.Pharm.Sci. 97
  
  Pages: 187-187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] N^ε-(Carboxymethyl)lysine proliferated CD34^+ cells from rat choroidal explant in culture2004
- Author(s)
  S Kobayashi, H Shinohara, H Tsuneki, R Nagai, S Horiuchi
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1382-1387
- NAID
  110003608980
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] Overproduction of N^ε-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of streptozotocin-diabetic rat2004
- Author(s)
  S Kobayashi, M Suzuki, H Tsuneki, R Nagai, S Horiuchi, N Hagino
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1565-1571
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] N^ε-(Carboxymethyl) lysine proliferated CD34^+ cells from rat choroidal explant in culture2004
- Author(s)
  S Kobayashi, H Shinohara, H Tsuneki, R Nagai, S Horiuchi
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1382-1387
- NAID
  110003608980
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590074
[Journal Article] Overproduction of N^ε-(Carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of streptozotocin-diabetic rat2004
- Author(s)
  S Kobayashi, M Suzuki, H Tsuneki, R Nagai, S Horiuchi, N Hagino
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1565-1571
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590074

1. KIMURA Masayasu (60019099)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KIMURA Ikuko (70019131)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HORIUCHI Seikoh (10117377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SHINOHARA Harumichi (20135007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. HAGINO Nobuyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOBAYASHI Shinjiro 古林 伸二郎

KOBAYASHI Shinjiroh 古林 伸二郎

Research Projects

Research Products

Co-Researchers

Roles of AGE for neovascularization and proliferation of fibroblast-like cells in cultured rat choroidal explainsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of AGE for mechanism of angiogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of drugs on abnormal neovascularization of choroidal capillaries in diabetic ratsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

糖尿病性血管平滑筋のインスリンによる培養細胞増殖機序とその抑制物質の研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

The mechanism of hypersensitization in diabetic state of neuromuscular synapse to depolarizing blockers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inhibitory effect of nifedipine on tumor necrosis factor a-induced neovascularization in cultured choroidal explant of streptozotocin-diabetic rat2005

Author(s)

Journal Title

Data Source

[Journal Article] Inhibitory effect of nifedipine on tumor necrosis factor a-induced neovascularization in cultured choroidal explants of streptozotocin-diabetic rat2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Antiangiogenic activity of beta-eudesmol in vitro and in vivo2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] A role of TNF-α for N^ε-(carboxymethyl)lysine-facilitated neovascularization of cultured choroidal explant in aged rat2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Inhibitory effect of nifedipine on tumor necrosis factor α-induced neovascularization in cultured choroidal explants of streptozotocin-diabetic rat2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Antiangiogenic activity of beta-eudesmol in vitro and in vivo2005

Author(s)

Journal Title

Data Source

[Journal Article] A role of TNF-α for N^ε-(carboxymethyl)lysine-facilitated neovascularization of cultured choroidal explant in aged rat2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] N^ε-(Carboxymethyl)lysine proliferated CD34^+ cells from rat choroidal explant in culture2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Overproduction of N^ε-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of streptozotocin-diabetic rat2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] N^ε-(Carboxymethyl) lysine proliferated CD34^+ cells from rat choroidal explant in culture2004

Author(s)

KOBAYASHI Shinjiro 古林伸二郎

KOBAYASHI Shinjiroh 古林伸二郎