Kunishima Munetaka 国嶋崇隆

… Alternative Names

Researcher Number	10214975
Other IDs
External Links
Affiliation (Current)	2019: 金沢大学, 薬学系, 教授
Affiliation (based on the past Project Information) *help	2008 – 2019: Kanazawa University, 薬学系, 教授 2007: Kobe Gakuin University, 薬学部, 教授 2006: 神戸学院大学, 薬学部, 助教授 2003 – 2004: 神戸学院大学, 薬学部, 助教授 2002: 神戸学院大学, 薬学部, 講師 1998 – 1999: 神戸学院大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Chemical pharmacy / Chemical pharmacy / Medium-sized Section 47:Pharmaceutical sciences and related fields Except Principal Investigator Radiation science / Tumor therapeutics / Medium-sized Section 52:General internal medicine and related fields / Medical pharmacy / Risk sciences of radiation and chemicals
Keywords	Principal Investigator トリアジン / アミド / 脱水縮合 / 脱水縮合剤 / 含窒素複素環 / アルキル化剤 / 脱離基 / 分子認識 / タンパク質検索 / カルボン酸 … More Except Principal Investigator 薬物代謝酵素活性 / 低分子化合物 / 個別化薬物療法 / 阻害剤 / ヌクレオチド除去修復 / 分子イメージング / トランスポータ / 可視化 / スクリーニング / 放射性画像診断薬 / 個別化治療 / 放射性診断薬 / シスプラチン / 副作用 / 増感作用 / MRP2 / 核医学 / 個体差要因 / 薬物誘導性肝障害 / 薬効・副作用の個体差要因 / 神経化学的評価 / 治療効果判定 / 治療効果 / 胆汁排泄 / 核医学画像診断法 / 汎用的基盤形成 / 遺伝子発現解析 / 薬物トランスポータ / 分子標的 / ケミカルバイオロジー / 個別化医療 / 肝細胞 / 多剤耐性 / 輸送体 / 小動物イメージング / 化合物ライブラリー / 精神神経疾患 / 抗がん剤 / SPECT / 個体差 / 抗癌剤 / 薬物間相互作用 Less

創薬・生命科学への展開を指向した短寿命高活性カルボカチオン種の制御Principal InvestigatorOngoing
- Principal Investigator
  
  国嶋崇隆
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kanazawa University
個別化薬物療法最適化の基盤となる薬物代謝酵素活性を評価する核医学画像診断法の確立Ongoing
- Principal Investigator
  
  川井恵一
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Kanazawa University
Development of novel reagents taking the advantage of the electron deficient nitrogen-containing heterocyclesPrincipal InvestigatorOngoing
- Principal Investigator
  
  国嶋崇隆
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
Development of high accuracy multidrug resistance prediction method using SPECT imaging for individualized anticancer therapy
- Principal Investigator
  
  KOBAYASHI Masato
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Development of novel pi-electron deficient nitrogen-containing heterocycles for dehydrocondensationsPrincipal Investigator
- Principal Investigator
  
  KUNISHIMA MUNETAKA
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
Asymmetric induction by using carbocations as a reactive speciesPrincipal Investigator
- Principal Investigator
  
  KUNISHIMA MUNETAKA
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
Application of chemical biology to a mechanistic study of human nucleotide excision repair
- Principal Investigator
  
  MATSUNAGA Tsukasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kanazawa University
Development of a molecular targeted radiolabeled diagnostic agent useful for personalized drug therapy of psychoneurotic diseases
- Principal Investigator
  
  KAWAI Keiichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Analysis of a novel small-molecule compound inducing the degradation of a cisplatin resistance-related factor ERCC1
- Principal Investigator
  
  MATSUNAGA Tsukasa
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kanazawa University
Development of Efficient Sensing Method for Targeting Proteins Based on Dehydrocondensing ReactionsPrincipal Investigator
- Principal Investigator
  
  KUNISHIMA MUNETAKA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
Application of Sandwich-cultured hepatocytes for analysis of drug-drug interaction on bile canalicular transporters
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
DEVELOPMENT OF REACTION FIEILDS FOR DEHYDROCONDENSATIONS TOWARD CREATION OF NEW TECHNOLOGIES ON THE BASIS OF TRIAZINE CHEMISTRYPrincipal Investigator
- Principal Investigator
  
  KUNISHIMA Munetaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
二本鎖脂質分子の膜内での化学合成によって誘起される膜の形態変化に関する研究Principal Investigator
- Principal Investigator
  
  国嶋崇隆
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kobe Gakuin University
Development and application of artificial acyltransferase models based on host compoundsPrincipal Investigator
- Principal Investigator
  
  KUNISHIMA Munetaka
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kobe Gakuin University
新規な分子インプリンティング法を用いた反応触媒高分子の開発Principal Investigator
- Principal Investigator
  
  国嶋宗隆
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kobe Gakuin University

[Book] 医療・診断をささえるペプチド化学－再生医療・DDS・診断への応用－2017
- Author(s)
  北村正典、国嶋崇隆
- Total Pages
  315
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-17H03970
[Book] e-EROS (Encyclopedia of Reagents for Organic Synthesis) 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl )-4-methylmorpholinium chloride2013
- Author(s)
  M. Kitamura, M. Kunishima
- Total Pages
  5
- Publisher
  John Wiley & Sons, Ltd
- Data Source
  KAKENHI-PROJECT-23590004
[Book] e-EROS (Encyclopedia of Reagents for Organic Synthesis)　4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride.2013
- Author(s)
  Masanori Kitamura, Munetaka Kunishima
- Total Pages
  5
- Publisher
  John Wiley & Sons, Ltd
- Data Source
  KAKENHI-PROJECT-23590004
[Book] 化学フロンティア19創薬をめざす有機合成最前線, 宍戸宏造, 新藤充編策1章トリアジン誘導体を用いた脱水縮合反応2007
- Author(s)
  国嶋崇隆(分担執筆)
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-18659006
[Book] フルオラスケミストリー2005
- Author(s)
  国嶋崇隆
- Total Pages
  9
- Publisher
  シーエムシー出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Book] 第5版実験化学講座 16 有機化合物の合成IV 酸アミド,ラクタム2005
- Author(s)
  国嶋崇隆
- Total Pages
  55
- Publisher
  丸善株式会社
- Data Source
  KAKENHI-PROJECT-14572025
[Book] 第5版実験化学講座第16巻,有機化合物の合成IV,1.7 酸アミドおよび酸イミド2005
- Author(s)
  国嶋崇隆
- Total Pages
  37
- Publisher
  丸善
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Book] 第5版実験化学講座第16巻,有機化合物の合成IV,1.8 ラクタム2005
- Author(s)
  国嶋崇隆
- Total Pages
  20
- Publisher
  丸善
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Development of Triazine-Based Benzylating Reagents Possessing t-Butyl Group on the Triazine Core: Thermally Controllable Reagents for the Initiation of Reaction2018
- Author(s)
 Karuo Yukiko、Yamada Kohei、Kunishima Munetaka
- Journal Title
 
 Chem. Pharm. Bull.
 
 Volume: 66 Issue: 3 Pages: 303-308
- DOI
 10.1248/cpb.c17-00897
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-17H03970
[Journal Article] Development of highly electron-deficient and less sterically-hindered phosphine ligands possessing 1,3,5-triazinyl groups2018
- Author(s)
  Kazumi Abe, Masanori Kitamura, Hikaru Fujita, Munetaka Kunishima
- Journal Title
  
  Mol Cat.
  
  Volume: 445 Pages: 87-93
- DOI
  10.1016/j.mcat.2017.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08161, KAKENHI-PROJECT-17H03970
[Journal Article] Development of radioiodine-labeled acetaminophen for specific, high-contrast imaging of malignant melanoma2018
- Author(s)
  Wen Jing Zhu , Masato Kobayashi , Kohei Yamada , Kodai Nishi , Kotaro Takahashi , Asuka Mizutani , Ryuichi Nishii , Leo G. Flores II , Naoto Shikano , Munetaka Kunishima , Keiichi Kawai
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 59 Pages: 16-21
- DOI
  10.1016/j.nucmedbio.2017.12.008
- Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05397, KAKENHI-PROJECT-15K09949
[Journal Article] N,N’-Dimethylated Benzyloxytriazinedione: A Stable Solid Reagent for Acid-Catalyzed O-Benzylation2017
- Author(s)
  Hikaru Fujita, Satoshi Kakuyama, Munetaka Kunishima
- Journal Title
  
  Eur. J. Org. Chem.
  
  Volume: 2017 Pages: 833-839
- DOI
  10.1002/ejoc.201601387
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293003
[Journal Article] Development of a method for the synthesis of 2,4,5-trisubstituted oxazoles composed of carboxylic acid, amino acid, and boronic acid2017
- Author(s)
  Yamada Kohei、Kamimura Naoto、Kunishima Munetaka
- Journal Title
  
  Beilstein J. Org. Chem.
  
  Volume: 13 Pages: 1478-1485
- DOI
  10.3762/bjoc.13.146
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03970
[Journal Article] Study of O-Allylation Using Triazine-Based Reagents2017
- Author(s)
 Kohei Yamada, Naoko Hayakawa, Hikaru Fujita, Masanori Kitamura, Munetaka Kunishima
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 65 Issue: 1 Pages: 112-115
- DOI
 10.1248/cpb.c16-00744
- Language
 English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
 KAKENHI-PROJECT-26293003, KAKENHI-PROJECT-16K08161
[Journal Article] トリアジンの特性を活用した新規アルキル化剤2017
- Author(s)
  国嶋崇隆，山田耕平，藤田光，北村正典
- Journal Title
  
  有機合成化学協会誌
  
  Volume: 75 Pages: 1023-1034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03970
[Journal Article] Development of Acid-Catalyzed Fluorous Benzylating Reagents Based on a Triazinedione Core2016
- Author(s)
  Munetaka Kunishima, Ryohei Asao, Kohei Yamada, Masanori Kitamura, Hikaru Fujita
- Journal Title
  
  J. Fluorine Chem.
  
  Volume: 190 Pages: 68-74
- DOI
  10.1016/j.jfluchem.2016.09.003
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293003, KAKENHI-PROJECT-16K08161
[Journal Article] Development of a Triazine-Based tert-Butylating Reagent, TriAT-tBu2016
- Author(s)
  Kohei Yamada, Naoko Hayakawa, Hikaru Fujita, Masanori Kitamura, Munetaka Kunishima
- Journal Title
  
  Eur. J. Org. Chem.
  
  Volume: 2016 Pages: 4093-4098
- DOI
  10.1002/ejoc.201600663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293003, KAKENHI-PROJECT-16K08161
[Journal Article] Hydroxy and Amino Group-Tolerant Synthesis of Six-Membered Cyclic Quaternary Ammonium Salts Using a Triazine-Based Reagent2016
- Author(s)
  Masanori Kitamura, Seina Yamamura, Kohei Yamada, Munetaka Kunishima
- Journal Title
  
  Asian J. Org. Chem.
  
  Volume: 5 Pages: 1508-1517
- DOI
  10.1002/ajoc.201600429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293003, KAKENHI-PROJECT-16K08161
[Journal Article] Potent triazine-based dehydrocondensing reagents substituted by an amido group2016
- Author(s)
  Munetaka Kunishima, Daiki Kato, Nobu Kimura, Masanori Kitamura, Kohei Yamada, Kazuhito Hioki
- Journal Title
  
  Beilstein J. Org. Chem.
  
  Volume: 12 Pages: 1897-1903
- DOI
  10.3762/bjoc.12.179
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293003, KAKENHI-PROJECT-16K08161
[Journal Article] Mild Amide-Cleavage Reaction Mediated by Electrophilic Benzylation2016
- Author(s)
  Kohei Yamada, Yukiko Karuo, Yuichi Tsukada, Munetaka Kunishima
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 22 Pages: 14042-14047
- DOI
  10.1002/chem.201603120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293003
[Journal Article] Study of the Reactivities of Acid-Catalyzed O-Benzylating Reagents Based on Structural Isomers of 1,3,5-Triazine.2015
- Author(s)
  Hikaru Fujita, Naoko Hayakawa, and Munetaka Kunishima
- Journal Title
  
  J. Org. Chem
  
  Volume: 80 Pages: 11200-11205
- DOI
  10.1021/acs.joc.5b02059
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J07110, KAKENHI-PROJECT-26670001, KAKENHI-PROJECT-26293003
[Journal Article] O-Benzylation of Carboxylic Acids Using 2,4,6-Tris(benzyloxy)-1,3,5-triazine (TriBOT) under Acidic or Thermal Conditions.2015
- Author(s)
  Kohei Yamada, Saki Yoshida, Hikaru Fujita, Masanori Kitamura, and Munetaka Kunishima
- Journal Title
  
  Eur. J. Org. Chem
  
  Volume: 36 Pages: 79978002-79978002
- DOI
  10.1002/ejoc.201501172
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J07110, KAKENHI-PROJECT-25460012, KAKENHI-PROJECT-25460013, KAKENHI-PROJECT-26670001, KAKENHI-PROJECT-26293003
[Journal Article] Specific Labeling of Streptavidin for Better Understanding of Ligand Modification in Modular Method for Affinity Labeling (MoAL)2014
- Author(s)
  Munetaka Kunishima, Daiki Kato, Shuichi Nakanishi, Masanori Kitamura, Kohei Yamada, Keiji Terao, Tomoya Asano
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: 62 Issue: 11 Pages: 1146-1150
- DOI
  10.1248/cpb.c14-00468
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460013, KAKENHI-PROJECT-26293003
[Journal Article] Development of a New Benzylating Reagent Spontaneously Releasing Benzyl Cation Equivalents at Room Temperature2014
- Author(s)
  Kohei Yamada, Yuichi Tsukada, Yukiko Karuo, Masanori Kitamura, Munetaka Kunishima
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 20 Pages: 12274-12278
- DOI
  10.1002/chem.201403158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460013, KAKENHI-PROJECT-26293003, KAKENHI-PROJECT-26670001
[Journal Article] Synthesis of Pyrrolidinium Salts Using a Triazine-based Reagent under Mild Conditions2014
- Author(s)
  Masanori Kitamura, Seina Yamamura, Hiroko Kobayashi, Mariko Yamamoto, Kayo Tada, Kazuhito Hioki, Kohei Yamada, Munetaka Kunishima
- Journal Title
  
  Chem. Lett.
  
  Volume: 43 Issue: 10 Pages: 1593-1595
- DOI
  10.1246/cl.140503
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460013, KAKENHI-PROJECT-26293003
[Journal Article] Role of Linkers in Tertiary Amines that Mediate or Catalyze 1,3,5-Triazine-based Amide-forming Reactions2014
- Author(s)
  M. Kitamura, F. Kawasaki, K. Ogawa, S. Nakanishi, H. Tanaka, K. Yamada, M. Kunishima
- Journal Title
  
  J. Org. Chem.
  
  Volume: 79 Pages: 3709-3714
- DOI
  10.1021/jo500376m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590004, KAKENHI-PROJECT-25460013, KAKENHI-PROJECT-26293003
[Journal Article] A New Method Using 2-Chloro-4,6-dimethoxy-1,3,5-triazine forFacile Elimination of Dimethylamino Groupin Eschenmoser's Methylenation forSynthesis of α,β-Unsaturated Esters2013
- Author(s)
  Kohei Yamada, Kazumasa Masaki, Yuri Hagimoto, Seina Kamiya, Munetaka Kunishima
- Journal Title
  
  Tetahedron Letters
  
  Volume: 54 Pages: 1758-1760
- DOI
  10.1016/j.tetlet.2013.01.092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590004, KAKENHI-PROJECT-23790009
[Journal Article] Binding of Sulforhodamine B to Human Serum Albumin: A Spectroscopic Study.2013
- Author(s)
  Kitamura M., Murakami K., Yamada K., Kawai K., Kunishima M.
- Journal Title
  
  Dyes and Pigments.
  
  Volume: 99(3) Pages: 588-593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293260
[Journal Article] Study of 1,3,5-Triazine-Based Catalytic Amide-Forming Reactions: Effect of Solvents and Basicity of Reactants2013
- Author(s)
  Munetaka Kunishima, Masanori Kitamura, Hiroyuki Tanaka, Ichiro Nakakura, Takahiro Moriya, Kazuhito Hioki
- Journal Title
  
  Study of 1,3,5-Triazine-Based Catalytic Amide-Forming Reactions: Effect of Solvents and Basicity of Reactants
  
  Volume: 61 Issue: 8 Pages: 882-886
- DOI
  10.1248/cpb.c13-00368
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590004, KAKENHI-PROJECT-25460013
[Journal Article] A Practical Method for p-Methoxybenzylation of Hydroxy Groups Using 2,4,6-Tris(p-methoxybenzyloxy)-1,3,5-triazine (TriBOT-PM)2013
- Author(s)
  Kohei Yamada, Hikaru Fujita, Masanori Kitamura, Munetaka Kuni shima
- Journal Title
  
  Synthesis
  
  Volume: 45 Pages: 2989-2997
- DOI
  10.1055/s-0033-1339713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J07110, KAKENHI-PROJECT-23590004, KAKENHI-PROJECT-25460013
[Journal Article] Binding of Sulforhodamine B to Human Serum Albumin : A Spectroscopic Study2013
- Author(s)
  Masanori Kitamura, Koji Murakami, Kohei Yamada, Keiichi Kawai, Munetaka Kunishima
- Journal Title
  
  Dyes Pigm
  
  Volume: 99 Pages: 588-593
- DOI
  10.1016/j.dyepig.2013.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590004
[Journal Article] A Novel Acid-Catalyzed O-Benzylating Reagent with the Smallest Unit of Imidate Structure2012
- Author(s)
  Kohei Yamada, Hikaru Fujita, Munetaka Kunishima
- Journal Title
  
  Org. Lett
  
  Volume: 14 Pages: 5026-5029
- DOI
  10.1021/ol302222p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590004, KAKENHI-PROJECT-23790009
[Journal Article] One-Pot Preparation of Oxazol-5(4H)-ones from Amino Acids in Aqueous Solvents2012
- Author(s)
 H. Fujita, M. Kunishima
- Journal Title
 
 Chem. Pharm. Bull
 
 Volume: 60 Issue: 7 Pages: 907-912
- DOI
 10.1248/cpb.c12-00291
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-23590004
[Journal Article] Substrate-Selective Dehydrocondensation at an Interface of Micelles and Emulsions of Common Surfactants2012
- Author(s)
  M. Kunishima, K. Kikuchi, Y. Kawai, K. Hioki
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 51 Pages: 2080-2083
- DOI
  10.1002/anie.201107706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590004
[Journal Article] Study on 1,3,5-Triazine Chemistry in Dehydrocondensation : Gauche Effect on the Generation of Active Triazinylammonium Species2012
- Author(s)
  Munetaka Kunishima, Takae Ujigawa, Yoshie Nagaoka, Chiho Kawachi, Kazuhito Hioki, Motoo Shiro
- Journal Title
  
  Chem. Eur. J
  
  Volume: 18 Pages: 15856-15867
- DOI
  10.1002/chem.201202236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590004
[Journal Article] New approach to oligotriazoles using a cobalt complex of propargyl azides as a synthetic component2011
- Author(s)
  Y.Tsukada, K.Yamada, M.Kunishima
- Journal Title
  
  Tetrahedron Lett. Vol 52,印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] Labeling study of avidin by modular method for affinity labeling (MoAL)2010
- Author(s)
  S.Nakanishi, H.Tanaka, K.Hioki, K.Yamada, M.Kunishima
- Journal Title
  
  Bioorg.Med.Chem.Lett. Vol.20
  
  Pages: 7050-7053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] Effects of stereochemistry and β-substituents on the rates of vinylic S_N2 reaction of hypervalent vinyl(phenyl)-λ3-iodanes with tetrabutylammonium halides2010
- Author(s)
  K.Miyamoto, T.Okubo, M.Hirobe, M.Kunishima, M.Ochiai
- Journal Title
  
  Tetrahedron Vol:66
  
  Pages: 5819-5826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] Convenient Modular Method for Affinity Labeling(MoAL Method)Based on a Catalytic Amidation2009
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Chem.Commun.
  
  Pages: 5597-5599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] A Simple Practical Method for Synthesis of 4,6-Dimethoxy-1,3,5-triazin-2(1H)-one Using Dimethylamine-Functionalized Solid-Phase Reagent2009
- Author(s)
  K.Hioki, K.Ohshima, Y.Sota, M.Tanaka, M.Kunishima
- Journal Title
  
  Synthesis
  
  Pages: 542-544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] Synthesis of Aza-bridged Calix(4-methoxy)triazines toward Flattened p-Conjugated Macrocycles2009
- Author(s)
  H.Tanaka, 1 A.Wada, M.Shiro, K.Hioki, D.Morisaki, M.Kunishima
- Journal Title
  
  Heterocycles Vol.79
  
  Pages: 609-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] Convenient Modular Method for Affinity Labeling (MoAL Method) Based on a Catalytic Amidation2009
- Author(s)
  M.Kunishima, S.Nakanishi, J.Nishida, H.Tanaka, D.Morisaki, K.Hioki, H.Nomoto
- Journal Title
  
  Chem. Commun.
  
  Pages: 5597-5599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] Convenient One-Pot Synthesis of 2-Oxazolines from Carboxylic Acids2008
- Author(s)
  K.Hioki, Y.Takechi, N.Kimura, H.Tanaka, M.Kunishima
- Journal Title
  
  Chem.Pharm.Bull. Vol.56
  
  Pages: 1735-1737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] 反応場の特性を基盤とする反応制御と実用的試薬の開発研究2008
- Author(s)
  国嶋崇隆
- Journal Title
  
  薬誌 Vol.128
  
  Pages: 425-438
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] Direct Preparation of Primary Amides by Reaction of Carboxylic Acids and Ammonia in Alcohols Using DMT-MM2008
- Author(s)
  T.Mizuhara, K.Hioki, M.Yamada, H.Sasaki, D.Morisaki, M.Kunishima
- Journal Title
  
  Chem Lett. Vol.37
  
  Pages: 1190-1191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] Antitumor Studies-Part 2 : Structure-Activity Relationship Study for Flavin Analogs Including Investigations on Their in vitro Antitumor Assay and Docking Simulation into Protein Tyrosine Kinase.2008
- Author(s)
  H.I.Ali, K.Tomita, E.Akaho, M.Kunishima, Y.Kawashima, T.Yamagishi, H.Ikeya, T.Nagamatsu
- Journal Title
  
  Eur.J.Med.Chem. Vol.43
  
  Pages: 1376-1389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] 反応場の特性を基盤とする反応制御と実用的試薬の開発研究2008
- Author(s)
  国嶋崇隆
- Journal Title
  
  薬学雑 3(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659006
[Journal Article] 機能拡張性を備えた実用的なポリマー型脱水縮合剤の開発2008
- Author(s)
  国嶋崇隆
- Journal Title
  
  薬学研究の進歩 Vol.24
  
  Pages: 29-35
- Data Source
  KAKENHI-PROJECT-20390007
[Journal Article] Primary-Amine-Specific Lactamization of ω-Amino Acids by an Artificial Cyclotransferase Based on [18]Crown-62006
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Angew.Chem.Int.Ed. 45-8
  
  Pages: 1252-1255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Primary-Amine-Specific Lactamization of ω-Amino Acids by an Artificial Cyclotransferase Based on 〔18〕Crown-62006
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Angew. Chem. Int. Ed. 45,8
  
  Pages: 1252-1255
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Spontaneous Membrane Fusion Induced by Chemical Formation of Ceramides in a Lipid Bilayer2006
- Author(s)
  M.Kunishima et al.
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 14452-14452
- Data Source
  KAKENHI-PROJECT-18659006
[Journal Article] Unusual Rate Enhancement of Bimolecular Dehydrocondensation Forming Amides at the Interface of Micelles of Fatty Acid Salt2005
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Angew. Chem. Int. Ed. 44,44
  
  Pages: 7254-7257
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Development of Novel Polymer-type Dehydrocondensing Reagents Comprised of Chlorotriazines2005
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Chem.Commun. 21
  
  Pages: 2698-2700
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Development of Novel Polymer-type Dehydrocondensing Reagents Comprised of Chlorotriazines2005
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Chem. Commun. 21
  
  Pages: 2698-2700
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] メディアとしての水の特性を利用したアミド化反応2005
- Author(s)
  国嶋崇隆
- Journal Title
  
  ファルマシア 44,7
  
  Pages: 654-658
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Unusual Rate Enhancement of Bimolecular Dehydrocondensation Forming Amides at the Interface of Micelles of Fatty Acid Salt2005
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Angew.Chem.Int.Ed. 44-44
  
  Pages: 7254-7257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] 新規トリアジン型脱水縮合剤の合成と用途開発2004
- Author(s)
  国嶋崇隆
- Journal Title
  
  和光純報 72
  
  Pages: 8-8
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Substrate-Specific Amidation of Carboxylic Acids in a Liquid-Liquid Two-Phase System Using Cyclodextrins As an Inverse Phase Transfer Catalyst2004
- Author(s)
  M.Kunishima, Y.Watanabe, K.Terao, S.Tani
- Journal Title
  
  Eur.J.Org.Chem.
  
  Pages: 4535-4535
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Substrate-Specific Amidation of Carboxylic Acids in a Liquid-Liquid Two-Phase System Using Cyclodextrins As an Inverse Phase Transfer Catalyst2004
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Eur. J. Org. Chem 22
  
  Pages: 4535-4540
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Substrate-Specific Amidation of Carboxylic Acids in a Liquid-Liquid Two-Phase System Using Cyclodextrins As an Inverse Phase Transfer Catalyst2004
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Eur J.Org.Chem. 22
  
  Pages: 4535-4540
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Development of a Simple System for Dehydrocondensation Using Solid-Phase Adsorption of a Water-Soluble Dehydrocondensing Reagent (DMT-MM)2004
- Author(s)
  Y.Watanabe, T.Fuji, K.Hioki, S.Tani, M.Kunishima
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages: 1223-1223
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Approach to Green Chemistry of DMT-MM : Recovery and Recycle of Coproduct to Chloromethane-Free DMT-MM2002
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Tetrahedron Lett. 43-18
  
  Pages: 3323-3326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Journal Article] Approach to Green Chemistry of DMT-MM : Recovery and Recycle of Coproduct to Chloromethane-Free DMT-MM2002
- Author(s)
  Munetaka Kunishima
- Journal Title
  
  Tetrahedron Lett., 43,18
  
  Pages: 3323-3326
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572025
[Presentation] トリアジンジオンを基盤とする新規アシル化剤の開発2017
- Author(s)
  古田美佳、軽尾友紀子、李政洙、山田耕平、北村正典、国嶋崇隆
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター、仙台
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] カルボン酸、アミノ酸、ボロン酸からなる多様性志向型三置換オキサゾール合成法の開発2017
- Author(s)
  山田耕平，上村直人，国嶋崇隆
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17H03970
[Presentation] 新規トリアジン型酸化剤の開発と反応2017
- Author(s)
  五十嵐佑貴、別役樹、山田耕平、国嶋崇隆
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター、仙台
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 実用的な酸触媒アルキル化剤の開発2017
- Author(s)
  角山哲史、藤田光、寺﨑博満、山田耕平、国嶋崇隆
- Organizer
  日本プロセス化学会 2017 サマーシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03970
[Presentation] トリアジニルピリジニウム塩を用いたエステル化反応の開発2017
- Author(s)
  劉杰、山田耕平、北村正典、国嶋崇隆
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター、仙台
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 求核触媒を内包した新規エステル化剤の開発2017
- Author(s)
  劉杰、山田耕平、北村正典、国嶋崇隆
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03970
[Presentation] 酸触媒ジアルキルトリアジンジオン型フルオラスベンジル化剤の開発2017
- Author(s)
  山田耕平，藤井崇徳，山下莉奈，国嶋崇隆
- Organizer
  フルオラス科学研究会第10回シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03970
[Presentation] Development of Electron-Poor Phosphine Ligands Having 1,3,5-Triazinyl Groups2017
- Author(s)
  Kazumi Abe, Masanori Kitamura, Hikaru Fujita, Munetaka Kunishima, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa, Japan
- Organizer
  26th International Society of Heterocyclic Chemistry
- Data Source
  KAKENHI-PROJECT-17H03970
[Presentation] カルボン酸・アミノ酸・アリールボロン酸からなる三置換オキサゾールの短工程合成法の開発2016
- Author(s)
  上村直人、山田耕平、藤田光、国嶋崇隆
- Organizer
  第46回複素環化学討論会
- Place of Presentation
  歌劇座、金沢
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] サイトⅠ特異的な薬物タンパク結合を検出する蛍光標識化アルブミンの開発2016
- Author(s)
  瀧澤祐美佳, 山田耕平, 国嶋崇隆
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] Development of HSA Sensor for Detection of Site II Drug Binding.2016
- Author(s)
  Kunishima M.
- Organizer
  Asian Chemical Biology Initiative (ACBI) 2016 Jakarta Meeting
- Place of Presentation
  Jakarta, Indonesia
- Year and Date
  2016-01-30
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] Development of triazine-type dehydrocondensing reagents having an amido group2016
- Author(s)
  Daiki Kato, Nobu Kimura, Kohei Yamada, Masanori Kitamura, Munetaka Kunishima
- Organizer
  XXVII European Colloquium on Heterocyclic Chemistry (ECHC 2016)
- Place of Presentation
  Beurs van berlage, Amsterdam, Netherlands
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 塩化トリアジンを用いた六員環状第四級アンモニウム塩合成法の開発2016
- Author(s)
  北村正典、山村聖奈、山田耕平、国嶋崇隆
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば国際会議場、つくば
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] アミド基を置換基に有するトリアジニルアンモニウム型脱水縮合剤の開発2016
- Author(s)
  古田美佳, 山田耕平, 藤田光, 国嶋崇隆
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 新規トリアジノン型脱水縮合剤の開発2016
- Author(s)
  古田美佳、高橋　健輔、山田耕平、藤田光、国嶋崇隆
- Organizer
  第46回複素環化学討論会
- Place of Presentation
  歌劇座、金沢
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 互変異性化を駆動力とした新規トリアジン型酸化剤の開発2016
- Author(s)
  五十嵐佑貴、山田耕平、平田紘基、国嶋崇隆
- Organizer
  日本薬学会北陸支部第128回例会
- Place of Presentation
  北陸大学、金沢
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] ポリアクリルアミドを担体とする親水性固定化脱水縮合剤の開発2016
- Author(s)
  夏俊卿, 山田耕平, 国嶋崇隆
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] アミノトリアジンを脱離基とするベンジル化剤の開発：置換基効果に基づく分解反応の制御2015
- Author(s)
  軽尾友紀子、小峰彩、北村正典、国嶋崇隆
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸、神戸学院大学
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] Development of a method for the synthesis of trisubstituted oxazoles by Suzuki-Miyaura Coupling2015
- Author(s)
  Yamada K, Kamimura N, Fujita H, Kunishima M.
- Organizer
  the 18th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-06-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] Development of acid-catalyzed alkylating reagents based on triazine chemistry2015
- Author(s)
  Hayakawa N, Yamada K, Fujita H, Kitamura M, Yoshimura K, Kunishima M.
- Organizer
  The 3rd International Symposium on Process Chemistry
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2015-07-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] トリアジン骨格を基盤とする酸触媒tert-ブチル化剤の開発2015
- Author(s)
  早川奈緒子、山田耕平、藤田光、国嶋崇隆
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸、神戸学院大学
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] π電子欠乏性新規トリアジン型脱水縮合剤の開発2015
- Author(s)
  木村円、矢内秀、山田耕平、北村正典、国嶋崇隆
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸、神戸学院大学
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] カルボン酸・アミノ酸・アリールボロン酸からなる三置換オキサゾール合成法の開発2015
- Author(s)
  上村直人、山田耕平、藤田光、国嶋崇隆
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸、神戸学院大学
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] Quick and mild methods for cleavage of amide-bonds by using a triazine-based benzylating reagent2015
- Author(s)
  Karuo Y, Yamada K, Kunishima M.
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] Study of the reactivity of benzyloxytriazine derivatives (BOTs) for acid catalyzed O-benzylation2015
- Author(s)
  Fujita H, Kunishima M.
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] 電子的効果の軽微な置換基を有するトリアジン型縮合剤の反応性に関する研究学会等名2015
- Author(s)
  小峰彩、北村正典、岡田有加里、国嶋崇隆
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸、神戸学院大学
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] トリアジン骨格を基盤とする酸触媒tert-ブチル化剤の開発2015
- Author(s)
  早川奈緒子、山田耕平、藤田光、国嶋崇隆
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸、神戸学院大学
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] トリアジン型酸触媒ベンジル化剤のジプロトン化機構によるO-ベンジル化反応2015
- Author(s)
  藤田光, 国嶋崇隆
- Organizer
  第41回反応と合成の進歩シンポジウム
- Place of Presentation
  近畿大学、大阪
- Year and Date
  2015-10-27
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] 薬物タンパク結合を検出する蛍光標識化アルブミンの開発2015
- Author(s)
  巻口真穂, 木野徹平, 山田耕平, 浅野智哉, 国嶋崇隆
- Organizer
  日本薬学会北陸支部第127回例会
- Place of Presentation
  富山大学、富山
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 電子欠乏性トリアジニルホスフィン配位子の開発2015
- Author(s)
  安倍一実、北村正典、国嶋崇隆
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸、クリエイティブセンター神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] Quick and mild methods for cleavage of amide-bonds by using a triazine-based benzylating reagent2015
- Author(s)
  Karuo Y, Yamada K, Kunishima M.
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] アミノトリアジンを脱離基とするベンジル化剤の開発：置換基効果に基づく分解反応の制御2015
- Author(s)
  軽尾友紀子、小峰彩、北村正典、国嶋崇隆
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸、神戸学院大学
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] Study of the reactivity of benzyloxytriazine derivatives (BOTs) for acid catalyzed O-benzylation2015
- Author(s)
  Fujita H, Kunishima M.
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 新規酸触媒トリアジノン型ベンジル化剤の開発2015
- Author(s)
  角山哲史, 藤田光, 北村正典, 山田耕平, 国嶋崇隆
- Organizer
  第45回複素環化学討論会
- Place of Presentation
  早稲田大学、東京
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] Development of acid-catalyzed alkylating reagents based on triazine chemistry2015
- Author(s)
  Hayakawa N, Yamada K, Fujita H, Kitamura M, Yoshimura K, Kunishima M.
- Organizer
  The 3rd International Symposium on Process Chemistry
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2015-07-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] イメージングによる肝臓の薬物代謝酵素CYP活性測定を可能にするヨウ素標識診断薬の開発2015
- Author(s)
  水谷明日香，髙橋浩太郎，外間つづみ，小林正和，北村正典，国嶋宗隆，川井恵一，福地一樹．
- Organizer
  第55回日本核医学会学術総会
- Place of Presentation
  ハイアットリージェンシー東京(東京都千代田区)
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-15K09949
[Presentation] 新規酸触媒トリアジノン型ベンジル化剤の開発2015
- Author(s)
  角山哲史, 藤田光, 北村正典, 山田耕平, 国嶋崇隆
- Organizer
  第45回複素環化学討論会
- Place of Presentation
  早稲田大学、東京
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] Effect of carbon substituents on the reactivity of triazine-based dehydrocondensing reagents2015
- Author(s)
  Komine S, Kitamura M, Kunishima M.
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 酸触媒ベンジル化剤TriBOTを用いた低環境負荷型エステル化反応の開発2014
- Author(s)
  山田耕平、吉田紗季、吉村和真、藤田光、北村正典、河合伸高、国嶋崇隆
- Organizer
  日本プロセス化学会２０１４サマーシンポジウム
- Place of Presentation
  東京、タワーホール船堀
- Year and Date
  2014-08-01
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 未知の薬物標的タンパク質の探索を志向した親和標識化法2014
- Author(s)
  加藤大輝, 北村正典, 山田耕平, 浅野智哉, 国嶋崇隆
- Organizer
  創薬懇話会 2014 in 岐阜
- Place of Presentation
  岐阜、岐阜長良川温泉　ホテルパーク
- Year and Date
  2014-07-09
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] トリアジニルアミンを脱離基とした分子内閉環反応によるピロリジニウム塩の合成2014
- Author(s)
  山村聖奈，北村正典，小林比呂子，山本真理子，多田佳世，日置和人，山田耕平，国嶋崇隆
- Organizer
  第40回反応と合成の進歩シンポジウム
- Place of Presentation
  仙台、東北大学　川内萩ホール
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 電子欠乏性アミノトリアジンを脱離基としたベンジル化剤の開発2014
- Author(s)
  軽尾友紀子, 塚田裕以智, 山田耕平, 北村正典, 国嶋崇隆
- Organizer
  第44回複素環化学討論会
- Place of Presentation
  北海道、札幌市民ホール
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] 電子欠乏性アミノトリアジンを脱離基としたベンジル化剤の開発2014
- Author(s)
  軽尾友紀子, 塚田裕以智, 山田耕平, 北村正典, 国嶋崇隆
- Organizer
  第44回複素環化学討論会
- Place of Presentation
  北海道、札幌市民ホール
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] Development of a new benzylating reagent which releases benzyl cation-like species at room temperature2014
- Author(s)
  Kohei Yamada, Yukiko Karuo, Yuichi Tsukada, Masanori Kitamura, Munetaka Kunishima
- Organizer
  14th Tetrahedron Symposium Asia Edition
- Place of Presentation
  Singapore、Singapore EXPO Convention and Exhibition Centre
- Year and Date
  2014-10-30
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] ベンジルカチオン種の求電子付加に基づくアミド結合開裂反応の開発2014
- Author(s)
  軽尾友紀子，山田耕平，北村正典，国嶋崇隆
- Organizer
  創薬懇話会 2014 in 岐阜
- Place of Presentation
  岐阜、岐阜長良川温泉　ホテルパーク
- Year and Date
  2014-07-09
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] Development of a new benzylating reagent which releases benzyl cation-like species at room temperature2014
- Author(s)
  Kohei Yamada, Yukiko Karuo, Yuichi Tsukada, Masanori Kitamura, Munetaka Kunishima
- Organizer
  14th Tetrahedron Symposium Asia Edition
- Place of Presentation
  Singapore、Singapore EXPO Convention and Exhibition Centre
- Year and Date
  2014-10-30
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] 酸触媒ベンジル化剤TriBOTを用いた低環境負荷型エステル化反応の開発2014
- Author(s)
  山田耕平、吉田紗季、吉村和真、藤田光、北村正典、河合伸高、国嶋崇隆
- Organizer
  日本プロセス化学会２０１４サマーシンポジウム
- Place of Presentation
  東京、タワーホール船堀
- Year and Date
  2014-08-01
- Data Source
  KAKENHI-PROJECT-26670001
[Presentation] 脱水縮合反応を基盤とするタンパク質修飾法（MoAL法）におけるプローブ設計とその評価2014
- Author(s)
  加藤大輝，山田耕平，北村正典，浅野　智哉，国嶋崇隆
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] ベンジルカチオン種の求電子付加に基づくアミド結合開裂反応の開発2014
- Author(s)
  軽尾友紀子，山田耕平，北村正典，国嶋崇隆
- Organizer
  創薬懇話会 2014 in 岐阜
- Place of Presentation
  岐阜、岐阜長良川温泉　ホテルパーク
- Year and Date
  2014-07-09
- Data Source
  KAKENHI-PROJECT-26293003
[Presentation] イミダートの最小単位のみで構成される酸触媒アリールメチル化剤の開発2013
- Author(s)
  山田耕平、藤田光、国嶋崇隆
- Organizer
  日本プロセス化学会２０１３サマーシンポジウム
- Place of Presentation
  つくば国際会議場（茨城県）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] カルボキシ基を標的とする生体分子の化学修飾2013
- Author(s)
  国嶋崇隆
- Organizer
  Endo-M研究会
- Place of Presentation
  金沢勤労者プラザ(石川県)
- Year and Date
  2013-05-17
- Invited
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] A new acid-catalyzed benzylating reagent with the smallest unit of imidate structure: TriBOT2013
- Author(s)
  Hikaru Fujita, Kohei Yamada, Munetaka Kunishima
- Organizer
  14th Tetrahedron Symposium
- Place of Presentation
  Hilton Vienna（Vienna, Austria）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] 古い化合物の新しい化学～1,3,5-トリアジンを基軸とする反応の開拓～2013
- Author(s)
  国嶋崇隆
- Organizer
  化学千一夜２０１３　「明日の化学への夢を語ろう」
- Place of Presentation
  参天製薬㈱能登工場（石川県）
- Invited
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] カルボキシ基を標的とする生体分子の化学修飾2013
- Author(s)
  国嶋崇隆
- Organizer
  Endo-M 研究会
- Place of Presentation
  金沢勤労者プラザ（石川県）
- Invited
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] ベンジルイミダートを経由するアミド結合切断反応の開発2013
- Author(s)
  軽尾友紀子，山田耕平，北村正典，国嶋崇隆
- Organizer
  第39回反応と合成の進歩シンポジウム
- Place of Presentation
  九州大学医学部百年講堂（福岡県）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] 酸触媒トリアジン型パラメトキシベンジル化剤 (TriBOT-PM) の開発2013
- Author(s)
  藤田光、山田耕平、北村正典、国嶋崇隆
- Organizer
  第43回複素環化学討論会
- Place of Presentation
  長良川国際会議場（岐阜県）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] 古い化合物の新しい化学〜1,3,5-トリアジンを基軸とする反応の開拓〜2013
- Author(s)
  国嶋崇隆
- Organizer
  化学千一夜2013「明日の化学への夢を語ろう」
- Place of Presentation
  参天製薬㈱能登工場(石川県)
- Year and Date
  2013-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] トリアジンの特性を利用した新反応剤の開発2012
- Author(s)
  国嶋崇隆
- Organizer
  日本プロセス化学会2012サマーシンポジウム
- Place of Presentation
  京都テルサ(京都府)
- Year and Date
  2012-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] 脱水縮合反応を利用したシクロオキシゲナーゼの特異的標識化反応2011
- Author(s)
  国嶋崇隆
- Organizer
  第37回反応と合成の進歩シンポジウム
- Place of Presentation
  あわぎんホール(徳島県)
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] 脱水縮合反応を利用したシクロオキシゲナーゼの特異的標識化反応2011
- Author(s)
  国嶋崇隆，鶴崎亮，中西修一，辻慎也，山田耕平
- Organizer
  第37回反応と合成の進歩シンポジウム
- Place of Presentation
  あわぎんホール（徳島）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] Specific Labeling of Avidin and Streptavidin by Modular Method for Affinity Labeling2011
- Author(s)
  S. Nakanishi, K. Yamada, M. Kunishima
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] カルボキシル基を標的とする生体分子の有機化学2011
- Author(s)
  国嶋崇隆
- Organizer
  日本薬学会九州支部主催特別講演会(招待講演)
- Place of Presentation
  長崎大学（長崎）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] Labeling Study of Cyclooxygenase-1 (COX-1) by Modular Method for Affinity Labeling (MoAL)2011
- Author(s)
  M. Kunishima, R. Tsurusaki, K. Yamada, S. Tsuji, S. Nakanishi
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] カルボキシル基を標的とする生体分子の有機化学2011
- Author(s)
  国嶋崇隆
- Organizer
  日本薬学会九州支部主催特別講演会
- Place of Presentation
  長崎大学(長崎県)
- Year and Date
  2011-06-06
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] An Efficient Dehydrocondensing Reaction Accelerated at a Micellar Interface2010
- Author(s)
  国嶋崇隆
- Organizer
  環太平洋化学会 (PacifiChem 2010)
- Place of Presentation
  ハワイコンベンションセンター(USA)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20390007
[Presentation] Convenient modular method for specific labeling of targeting proteins by catalytic amidation: MoAL Method2010
- Author(s)
  Munetaka Kunishima
- Organizer
  環太平洋化学会(PacifiChem2010)
- Place of Presentation
  ハワイコンベンションセンター(U.S.A.)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20390007
[Presentation] An Eflicient Dehydrocondensing Reaction Accelerated at a Micellar Interface2010
- Author(s)
  Munetaka Kunishima
- Organizer
  環太平洋化学会(PacifiChem2010)
- Place of Presentation
  ハワイコンベンションセンター(U.S.A.) 招待講演
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20390007
[Presentation] 触媒的脱水縮合反応を基盤とするモジュール式アフィニティーラベル化法(MoAL 法)の開発2009
- Author(s)
  国嶋崇隆
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸市産業振興センター(兵庫県)
- Year and Date
  2009-05-19
- Data Source
  KAKENHI-PROJECT-20390007
[Presentation] 触媒的脱水縮合反応を基盤とするモジュール式アフィニティーラベル化法(MoAL法)の開発2009
- Author(s)
  国嶋崇隆
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸市産業振興センター(兵庫)
- Year and Date
  2009-05-19
- Data Source
  KAKENHI-PROJECT-20390007
[Presentation] トリアジン型脱水縮合剤の開発と応用2009
- Author(s)
  国嶋崇隆
- Organizer
  平成21年度前期有機合成化学講習会
- Place of Presentation
  長井記念ホール(東京都)
- Year and Date
  2009-06-17
- Data Source
  KAKENHI-PROJECT-20390007
[Presentation] 生体分子を標的とする特異的アミド化反応2008
- Author(s)
  国嶋崇隆
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-18659006
[Presentation] 酸アミド結合の効率的な形成を目指した新技術の開拓 -トリアジン型縮合剤の開発と応川-2008
- Author(s)
  国嶋崇隆
- Organizer
  名城大学大学院総合学術研究科グリーンバイオビジネス創製プロジェクト平成20年度第4回プロジェクトセミナー
- Place of Presentation
  名城大学
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-20390007
[Presentation] 界面を反応場とする脱水縮合反応2007
- Author(s)
  国嶋崇隆
- Organizer
  平成19年度第1回粉体接合研究会
- Place of Presentation
  神戸
- Year and Date
  2007-06-27
- Data Source
  KAKENHI-PROJECT-18659006
[Presentation] トリアジンの特性を利用した新反応剤の開発
- Author(s)
  国嶋崇隆，鶴崎亮，中西修一，辻慎也，山田耕平
- Organizer
  日本プロセス化学会 2012 サマーシンポジウム
- Place of Presentation
  京都テルサ（京都府）
- Invited
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] プロトン性溶媒中でのエナンチオ選択的アミド化触媒の開発．
- Author(s)
  正木一将、北村正典、国嶋崇隆
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] Synthesis and Evaluation of Iodinated Cyclopropanecarboxylic Acid {3-[6-(Phenylamino)- pyrimidin-4-ylamino]-phenyl}-amides as EGFR-TK Imaging Agents.
- Author(s)
  Yoshimoto M., Kimura S., Yamada K., Hirata M., Ohmomo Y., Kunishima M., Kawai K., Fujii H.
- Organizer
  20th International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Jeju International Convention Center (Korea)
- Data Source
  KAKENHI-PROJECT-25293260
[Presentation] Preparation of Hydrogel Particles by a in situ Generated Condensing Agent
- Author(s)
  K. Iwahara, K. Hioki, M. Kitamura, K. Yamada, H. Ichikawa, M. Kunishima
- Organizer
  IKCOC12
- Place of Presentation
  リーガロイヤルホテル京都（京都府）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] 血清アルブミンに対する薬物の結合を簡便に検出するセンサーの開発
- Author(s)
  木野　徹平,　山田　耕平,　浅野　智哉,　国嶋　崇隆
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パフィシコ横浜(神奈川県）
- Data Source
  KAKENHI-PROJECT-23590004
[Presentation] 究極的に簡素化されたイミダート等価構造を持つ新規ベンジル化剤：TriBOT
- Author(s)
  藤田光、山田耕平、国嶋崇隆
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-23590004

1. YAMADA Kohei (40583232)

# of Collaborated Projects: 4 results

# of Collaborated Products: 61 results
2. TAMAI Ikumi (20155237)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KAWAI Keiichi (30204663)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. KITAMURA Masanori (80453835)

# of Collaborated Projects: 3 results

# of Collaborated Products: 41 results
5. MATSUNAGA Tsukasa (60192340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. INOBE Manabu (10312414)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. WAKASUGI Mitsuo (80345595)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ODA Akifumi (50433511)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KOBAYASHI Masato (30444235)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 石田康 (20212897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 間賀田泰寛 (20209399)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. HIOKI Kazuhito (70268522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. HOJO Keiko (20289028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TANAKA Hiroyuki (40378873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. MORISAKI Daiki (30462740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. NAKANISHI Takeo (30541742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. GOTO Kyoko (70634179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NISHINAGA Mari (10646681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ENDO Yoshio (30211783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. OKAZAWA Hidehiko (50360813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NISHII Ryuichi (60463212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. SHIKANO Naoto (80295435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. NISHI Kodai (10719496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 久下裕司 (70321958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 三代憲司 (60776079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. INNIS B Robert

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 水谷陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kunishima Munetaka 国嶋 崇隆

KUNISHIMA Munetaka 国嶋 崇隆

国嶋 宗隆 クニシマ ムネタカ

Research Projects

Research Products

Co-Researchers

創薬・生命科学への展開を指向した短寿命高活性カルボカチオン種の制御Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

個別化薬物療法最適化の基盤となる薬物代謝酵素活性を評価する核医学画像診断法の確立Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel reagents taking the advantage of the electron deficient nitrogen-containing heterocyclesPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of high accuracy multidrug resistance prediction method using SPECT imaging for individualized anticancer therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel pi-electron deficient nitrogen-containing heterocycles for dehydrocondensationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Asymmetric induction by using carbocations as a reactive speciesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of chemical biology to a mechanistic study of human nucleotide excision repair

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a molecular targeted radiolabeled diagnostic agent useful for personalized drug therapy of psychoneurotic diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of a novel small-molecule compound inducing the degradation of a cisplatin resistance-related factor ERCC1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Efficient Sensing Method for Targeting Proteins Based on Dehydrocondensing ReactionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of Sandwich-cultured hepatocytes for analysis of drug-drug interaction on bile canalicular transporters

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DEVELOPMENT OF REACTION FIEILDS FOR DEHYDROCONDENSATIONS TOWARD CREATION OF NEW TECHNOLOGIES ON THE BASIS OF TRIAZINE CHEMISTRYPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

二本鎖脂質分子の膜内での化学合成によって誘起される膜の形態変化に関する研究Principal Investigator

Principal Investigator

Kunishima Munetaka 国嶋崇隆

KUNISHIMA Munetaka 国嶋崇隆

国嶋宗隆クニシマムネタカ

[Book] e-EROS (Encyclopedia of Reagents for Organic Synthesis)　4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride.2013

[Book] 第5版実験化学講座 16 有機化合物の合成IV 酸アミド,ラクタム2005